LOCUS       NZ_CP083672            20732 bp    DNA     circular CON 04-NOV-2023
DEFINITION  Staphylococcus aureus strain HL25870 plasmid pHL25870, complete
            sequence.
ACCESSION   NZ_CP083672
VERSION     NZ_CP083672.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN20667808
            Assembly: GCF_020097755.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 20732)
  AUTHORS   Kim,J.-M., Chung,S.H. and Kim,J.-S.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-SEP-2021) Laboratory Medicine, Hallym university
            college of medicine, 150 Seongan-ro, Gangdong-gu, Seoul 05355,
            Republic of Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 08-JUL-2021
            Assembly Method                   :: SPAdes v. 3.14.0
            Assembly Name                     :: HL25870
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 262.0x
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/04/2023 04:54:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,795
            CDSs (total)                      :: 2,713
            Genes (coding)                    :: 2,628
            CDSs (with protein)               :: 2,628
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 85
            CDSs (without protein)            :: 85
            Pseudo Genes (ambiguous residues) :: 0 of 85
            Pseudo Genes (frameshifted)       :: 45 of 85
            Pseudo Genes (incomplete)         :: 37 of 85
            Pseudo Genes (internal stop)      :: 25 of 85
            Pseudo Genes (multiple problems)  :: 18 of 85
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP083672.1.
            Bacteria and source DNA available from Department of clinical
            laboratory, Kangdong Sacred Hospital.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..20732
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="HL25870"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pHL25870"
                     /geo_loc_name="South Korea"
                     /lat_lon="37.53639137 N 127.13541226 E"
                     /collection_date="2020"
                     /collected_by="Kangdong Sacred Hospital"
     gene            1..846
                     /gene="blaZ"
                     /locus_tag="K3A99_RS13825"
                     /old_locus_tag="K3A99_002735"
     ARG             2..843
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            1215..1823
                     /locus_tag="K3A99_RS13830"
                     /old_locus_tag="K3A99_002736"
     CDS             1215..1823
                     /locus_tag="K3A99_RS13830"
                     /old_locus_tag="K3A99_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002436987.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001566953.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGKSIENRPV
                     LQEALNFLRMGDRFVVESIDCLGRNYDEVIHTVNYLKDKEVQLMITSLPMMNEVVGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGQSISKIAKEVNITRQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            2237..2530
                     /locus_tag="K3A99_RS13835"
                     /old_locus_tag="K3A99_002737"
     CDS             2237..2530
                     /locus_tag="K3A99_RS13835"
                     /old_locus_tag="K3A99_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WP_000726502.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            2605..4539
                     /locus_tag="K3A99_RS13840"
                     /old_locus_tag="K3A99_002738"
     CDS             2605..4539
                     /locus_tag="K3A99_RS13840"
                     /old_locus_tag="K3A99_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WP_000713729.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTAIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLILKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTLDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            4543..4854
                     /locus_tag="K3A99_RS13845"
                     /old_locus_tag="K3A99_002739"
     CDS             4543..4854
                     /locus_tag="K3A99_RS13845"
                     /old_locus_tag="K3A99_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WP_000831610.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            4866..5492
                     /locus_tag="K3A99_RS13850"
                     /old_locus_tag="K3A99_002740"
     CDS             4866..5492
                     /locus_tag="K3A99_RS13850"
                     /old_locus_tag="K3A99_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000593103.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            5730..6359
                     /gene="mobV"
                     /locus_tag="K3A99_RS13855"
                     /pseudo=""
     CDS             5730..6359
                     /gene="mobV"
                     /locus_tag="K3A99_RS13855"
                     /inference="COORDINATES: protein motif:HMM:NF013258.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            6453..6998
                     /locus_tag="K3A99_RS13860"
                     /old_locus_tag="K3A99_002743"
     CDS             6453..6998
                     /locus_tag="K3A99_RS13860"
                     /old_locus_tag="K3A99_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001805533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000273005.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTDFEKYTKQIKAAQMILD
                     DYECIKSGKSLKKAEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQEREIIFKEDREDGYTL"
                     /name="hypothetical protein"
     gene            7382..8242
                     /locus_tag="K3A99_RS13865"
                     /old_locus_tag="K3A99_002744"
     CDS             7382..8242
                     /locus_tag="K3A99_RS13865"
                     /old_locus_tag="K3A99_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000145511.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            8329..8670
                     /locus_tag="K3A99_RS13870"
                     /old_locus_tag="K3A99_002745"
     CDS             8329..8670
                     /locus_tag="K3A99_RS13870"
                     /old_locus_tag="K3A99_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000761341.1"
                     /translation="MKLAEAIKEQRELKGWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRVPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(8909..8980)
                     /locus_tag="K3A99_RS13875"
                     /old_locus_tag="K3A99_002746"
     CDS             complement(8909..8980)
                     /locus_tag="K3A99_RS13875"
                     /old_locus_tag="K3A99_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_106873653.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGY"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            9129..9314
                     /locus_tag="K3A99_RS13880"
                     /old_locus_tag="K3A99_002747"
     CDS             9129..9314
                     /locus_tag="K3A99_RS13880"
                     /old_locus_tag="K3A99_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466619.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSVWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            complement(9533..10276)
                     /locus_tag="K3A99_RS13885"
                     /old_locus_tag="K3A99_002748"
     CDS             complement(9533..10276)
                     /locus_tag="K3A99_RS13885"
                     /old_locus_tag="K3A99_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843758.1"
                     /translation="MKSVKRLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESATEDKQKKESDNINFESKSDAQIVEILKNQINTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNAR
                     QNVDAQEKTYTTSPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAQREDVSANPND
                     NDSDIEEKSEETEPKKGFWSRLFGN"
                     /name="DUF536 domain-containing protein"
     gene            10687..11363
                     /locus_tag="K3A99_RS13890"
                     /old_locus_tag="K3A99_002749"
                     /pseudo=""
     CDS             10687..11363
                     /locus_tag="K3A99_RS13890"
                     /old_locus_tag="K3A99_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            <11374..11656
                     /locus_tag="K3A99_RS13895"
                     /pseudo=""
     CDS             <11374..11656
                     /locus_tag="K3A99_RS13895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            12868..13485
                     /gene="cadD"
                     /locus_tag="K3A99_RS13900"
                     /old_locus_tag="K3A99_002750"
     ARG             12869..13482
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="99.51"
                     /coverage="100.0"
     gene            13504..13851
                     /locus_tag="K3A99_RS13905"
                     /old_locus_tag="K3A99_002751"
     CDS             13504..13851
                     /locus_tag="K3A99_RS13905"
                     /old_locus_tag="K3A99_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119691.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNQEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            14020..14112
                     /locus_tag="K3A99_RS13910"
                     /old_locus_tag="K3A99_002752"
     CDS             14020..14112
                     /locus_tag="K3A99_RS13910"
                     /old_locus_tag="K3A99_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            14324..14890
                     /locus_tag="K3A99_RS13915"
                     /old_locus_tag="K3A99_002753"
     CDS             14324..14890
                     /locus_tag="K3A99_RS13915"
                     /old_locus_tag="K3A99_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="WP_049882581.1"
                     /translation="MSNTKIKYQIFISSTYLDLIEERQAVVEAVLNSNNIPAGMELFNS
                     SSKSQWEIITQWINESDAVILLLGSSYGTIDSEENISYTEMEYNFAKSLGKPIYVFEMN
                     KASTESAEKSKKLDEFKTKVKENRLISPNINDISELKSKVSQTLMQSVPSEIKENSGWI
                     RVQDCGKNVKKIKKIGCYTKRFRYI"
                     /name="DUF4062 domain-containing protein"
     gene            14895..15299
                     /locus_tag="K3A99_RS13920"
                     /old_locus_tag="K3A99_002754"
     CDS             14895..15299
                     /locus_tag="K3A99_RS13920"
                     /old_locus_tag="K3A99_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_106669568.1"
                     /translation="MKEELYKIFMYVKTFYFQHTPFDDSYIEDIENYLLNYENNPHKSF
                     MKIKVYDYKNFLKHLKNILILIKQGKKPLAQAGHFKLSFYEEDLKLLQKNYKTTLVDIK
                     GLNKHFYKECDRCLKAYNIFIEGINKHLYE"
                     /name="hypothetical protein"
     gene            complement(15419..16234)
                     /locus_tag="K3A99_RS13925"
                     /old_locus_tag="K3A99_002755"
     CDS             complement(15419..16234)
                     /locus_tag="K3A99_RS13925"
                     /old_locus_tag="K3A99_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000164958.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYNAPAEKQTKLRNDLYSITAIIDL
                     GQKLHVVNKYGHEHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            complement(16227..17670)
                     /locus_tag="K3A99_RS13930"
                     /old_locus_tag="K3A99_002756"
                     /pseudo=""
     CDS             complement(16227..17670)
                     /locus_tag="K3A99_RS13930"
                     /old_locus_tag="K3A99_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /name="DDE-type integrase/transposase/recombinase"
     gene            complement(17642..18235)
                     /locus_tag="K3A99_RS13935"
                     /old_locus_tag="K3A99_002757"
     CDS             complement(17642..18235)
                     /locus_tag="K3A99_RS13935"
                     /old_locus_tag="K3A99_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690638.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            complement(18499..18879)
                     /gene="blaI"
                     /locus_tag="K3A99_RS13940"
                     /old_locus_tag="K3A99_002758"
     ARG             complement(18503..18879)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            complement(18869..20626)
                     /gene="blaR1"
                     /locus_tag="K3A99_RS13945"
                     /old_locus_tag="K3A99_002759"
     ARG             complement(18873..20626)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.56"
                     /coverage="100.0"
     ARG             2..846
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.44"
                     /coverage="100.0"
     BGC             1..7530
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          11714..11861
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.333"
                     /coverage="100.0"
                     /evalue="2.96e-25"
     Typing          7383..8242
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(9534..10276)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          5731..6005
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="94.565"
                     /coverage="100.0"
                     /evalue="4.71e-46"
ORIGIN
        1 ttgaaaaagt taatattttt aattgtaatg gctttagttt taagtgcatg taattcaaac
       61 agttcacatg ccaaagagtt aaatgattta gaaaaaaaat ataatgctca tattggtgtt
      121 tatgctttag atactaaaag tggtaaggaa gtaaaattta attcagataa gagatttgcc
      181 tatgcttcga cttcaaaagc gataaatagt gctattttgt tagaacaagt accttataat
      241 aagttaaata aaaaagtaca tattaacaaa gatgatatag ttgcttattc tcctatttta
      301 gaaaaatatg taggaaaaga catcacttta aaagaactta ttgaggcttc aatgacatat
      361 agtgataata cagcaaacaa taaaattata aaagaaatcg gtggaatcaa aaaagttaaa
      421 caacgtctaa aagaactagg agataaagta acaaatccag ttagatatga gatagaatta
      481 aattactatt cgccaaagag caaaaaagat acttcaacgc ctgctgcttt cggcaagact
      541 ttaaataaac ttatcgcaaa tggaaaatta agcaaaaaaa ataaaaattt cttacttgat
      601 ttaatgttta ataataaaaa cggagacact ttaattaaag atggtgttcc aaaagactat
      661 aaggttgctg ataaaagtgg tcaagcaata acatatgctt ctagaaatga tgttgctttt
      721 gtttatccta agggccaatc tgaacctatt gttttagtca tttttacgaa taaagacaat
      781 aaaagtgata agccaaatga taagttgata agtgaaaccg ccaagagtgt aatgaaggaa
      841 ttttaatatt ctaaatgcat aataaatact gataacatct tatagtttgt attatatttt
      901 ctattatcgt tgacatgtat aattttgata tcaaaacctg attttccctt tattattttc
      961 gagatttatt ttcttaattc tctttaacaa actagaaata ttgtatatac aaaaaatcat
     1021 aaataataga tgaatagttt aattataggt gttcatcaat cgaaaaagca acgtatctta
     1081 tttaaagtgc gttgcttttt tctcatttat aaggttaaat aattctcata tatcaagcaa
     1141 agtgacataa ttgttgaatt tatagtaact gaaacgtatg attagggtgt atattaatta
     1201 tgagatggaa atcaatgatt gttggctatg cgagagtatc atcgaacgat caaaatttag
     1261 aaagacaact tgaaaattta aagacgtttt gtgctgaaaa aatatttaca gaaaaacagt
     1321 ctgggaaatc tattgaaaat agaccagtac ttcaagaagc acttaacttt ttgaggatgg
     1381 gagatcggtt tgtagtagaa tccattgatt gtttaggtcg taattatgat gaagtgattc
     1441 ataccgttaa ttatttaaaa gacaaagaag tacaattaat gattactagc ttacctatga
     1501 tgaatgaagt ggttggcaat ccattactgg ataagtttat gaaagattta attattcaaa
     1561 tattagcaat ggtttcagaa caagagagaa atgaaagtaa acgtcgacaa gcgcaaggaa
     1621 ttcaagttgc gaaggaaaaa ggcgtatata aagggcgccc cttactttat tcaccaaatg
     1681 ctaaagatcc acagaaacgt attatttatc atcgcgttgt agaaatgtta gaagaaggcc
     1741 aatcaattag taaaattgcg aaagaagtaa atataacaag gcagacgatt tacagaatta
     1801 aaaacgataa tgatttgatt taataaactt tgtttcaatg caactgagag cttctcacag
     1861 cgtctcaaaa cagatgatta taatctatta tgagttttta ataataagac aagaaaagag
     1921 agcgtaaata tgctctctct ttttctcatt aacgaatgtt tataacgcaa tcatgatgag
     1981 agtattaata cagttaatta tttgaaatac tttagtttat ataatgttga attataggta
     2041 gtgaaattgt atttattata cattgtcata tcgttgttta atgatagtta atttaaggat
     2101 aatagaatta atattatata tagatgaaca aaacaagcaa cagagcagaa aaaacacttt
     2161 tagattattt ttactcattc tctattttat ttatttttgc tataataaat aaagaatatt
     2221 aaatggaggt gtttttatga aaaagaaatt tgtttctagt tgtattgcta gtacaatctt
     2281 attcggcact ttattaggtg taacttataa agctgaagct gcaacagtac atgtagctgg
     2341 tggtgtttgg agccatggta ttggaaaaca ttacgtatgg tcttattata gtcacaataa
     2401 aagaaatcat ggttcaacag cagtagggaa atattcatct tttagtggtg ttgctcgacc
     2461 tggtgttcaa tctaaggcat ctgctccaaa ggcttggggt ggaaacaaaa cattttatag
     2521 tcttcactaa ttacatatat taattaagga gaatagacag aattaagtaa acttaattct
     2581 gtctattctc ttgaaagagg caatatgaaa aaattcaaat tatttttaga ttttagtact
     2641 ttattattaa tttcagggct attattttta tttttcttca aagaaaatga agaaattata
     2701 cctgaaagtt ccaatatttt aacaatctct aattgggata aatctaacag taaatcaaaa
     2761 gtgttagatg tcattgaatc aggcgccaaa aatcaaaata tacaaataat taaatccgtt
     2821 aaagattttg ataataaaaa agaatttttt gttttcaact caaaacgaaa taattctgac
     2881 tttatacgta ataaaacatc acttttaact ccatcagatt tattaaacag agagataaaa
     2941 ggaaagtatt atattattgg tgaacatttc aatgtagaag agcttacgag tgaattaaaa
     3001 aaagctggtt taacatctga agttgaatac ataaatagaa acatattatt ttttgaatta
     3061 gtcatagata atgatttatt agtgcctttc atattcttag gcgtattata tcttttgtac
     3121 ttcttatatg acagaggata taatttgaaa ttttatgcta ttcaaaagct acatggcttt
     3181 tcaactacac gcattatttt tcataatatt catataaaaa tcatttattg gctagtactt
     3241 accgctattt tctttattgc taatatatta atcattcata tagccaattt agaattggat
     3301 ttcttaatgt ttattcgtag atttatcgtg ttgctttttg tttttgcttg tattactaca
     3361 ttgctgtggc tgatttcgta tagtcttctt ttgaagttaa gtattccatt aatcttaaaa
     3421 gggaaaaaag gatataagtt ttcaatattt atgggtacct tcaccaaatg tatcatggtg
     3481 ctaatactat cttttttact ggcacaaaat ttaaatgctt atacgaagtt aaagaatata
     3541 tatgactctg aaaaaatctg gcaaaagtta gataattact atacattaga gatttctcct
     3601 aatattagaa attcagaaga aaaacaaatt ttagaaacta atatatacaa tttaattaag
     3661 aaaagcgaac aacttggtgg attgctttta aagaataata atatagccaa tcccgataaa
     3721 aacaattaca ttcctgaaaa tggcaatgtc ttttttatca ataacaattt tctgaatttc
     3781 tataaaaata taaatcatga ttttaaaatg attgacaatc attcggataa aataaacgtg
     3841 tttattcctc caaggttaca atatcaaaaa tctgaaattc aaaaaaatca ccaaggatgg
     3901 attgactttc aaaagcaaca aaacaaaaaa gtagatgtgc aagtactgtc aaaaaacgta
     3961 tctgtttttt cttttgatcg cacaactaat ttgaaatttg ggtatctaga ttctccaata
     4021 gtaatgttgt tgacacttga cgatttaaca ggagattttt atttagctgc tgtttctcaa
     4081 ggtggatatc tatttaaaga tttagataca cttaaacagt tgcttaaaga taatcaccta
     4141 gaagaagaaa ttagcggtat aactaattac aaggattctg tgttaaatga attaaatgaa
     4201 acgaaaacaa aaatgataat aacaatagtt actattatta ttaacgtttt cattcttttg
     4261 atagctactg tatttgaaac aattcaatat tttagctgga ataaaaagca actattatta
     4321 agaaaaattc atggttattc attattcagc agtaatgtac gttatttaac aatttctatc
     4381 ttactttcta ttatgttagc ttacactacg catattttat ttggttcaaa gatattacta
     4441 ttcataataa tgtctattgc tattattcaa catttacttc aaattgctta tattaaatat
     4501 cttgaaaaat actttaaaga tttaatgagg gagatttaaa caatgaaaag aactttaatt
     4561 attgtaacaa ttgtactatt aatcatcata cttagtctgt tattggttag aaatgagcat
     4621 ttagatcgtt ttaacccact gttaaaagaa aaagtatctt atgccaaagt tccaaaagat
     4681 acccaggact atagaaatat aactgtatac tctaaaaatg gagaaaaaaa gagttataaa
     4741 ttggattttt taggttatga tcctacaaaa gaatatgtga aagtaaatca taaagggaaa
     4801 tatgtgcgtt cgatagaata cattacaaaa gatattccta gctttttaaa atgaggtgac
     4861 cgatagtgat aaaacttgaa aatgtttttg taaaaaaagg taataaaaac attttagacg
     4921 gatgtaactt taattttgaa aaaggaaaat catatgcttt agttggagaa agtggcgctg
     4981 gaaaatctac tttacttaac ataatcgctg ggttcgaaga tgtatcacaa ggaagcatat
     5041 atattgaaga taagttacta aaaaagaaag tcgattttta tagatatacg ttagggtatt
     5101 tgtttcaaaa ttttgcttta cttgaaaatc aaacaatcag tcaaaattta gatttagccc
     5161 taaagttcaa aaagaataaa aaagataata tgaacttaaa gaaagaagta ttaaaaaagg
     5221 tcggcctaga tttagatatc aagagaattg ttagttctct aagcggtggt gaacaacaaa
     5281 gagtagcatt ggcaagatta atattaaaag atccgaaaat cattttagct gatgaaccta
     5341 ctgggtcact agatacgaaa aatggaaaaa tagttattga tttattattg aagctacttg
     5401 atgaaaataa aactatgatt gtcgtaacgc atgatttaga gcttgcgaaa cgatttgatg
     5461 tcatagtcaa tatttctgag cttagaagtt aagaaatatt gataggtata gccatacata
     5521 gagaaaaaac aatatgaaat atgattagtc attacttttg agttttttaa tttaaggact
     5581 ggattttcca gtcctttttt atgatgacaa aaaacaagcc tcgcagagca cacgttttta
     5641 atgacttatt tggtttttaa taagtctagt atgttaaaac ttttctgtgt ttaggtgtta
     5701 taatcatatg cagtggaagt tgatttatta tgtcttattc aattattcga gttgttaaag
     5761 tgaaatcaaa aacaaataca agaggtattc aaagacatat tcaaagagaa aataaaaatt
     5821 atgaaaatat agatattgat ttaagtaagt catatttaaa ctatgattta gtcaatgata
     5881 ctaagtttga ttttaataaa aaaattgatg agaaaatcga aaaaaattat aaagggaaac
     5941 gcaaaattag aacagatgcc attaaacata ttgatggatt aattacatca gataatgtgt
     6001 tttttaatca attatctgaa gaagagacaa aatagttttt taagcatgct aaagcgttct
     6061 tggaagaaga atacggtaaa gaaaatcttt tatatgcgac agtacatatg gatgagataa
     6121 caccacatat gcattatggc gtagttccta ttactaaaga tggacgttta agtgcgaaag
     6181 aagttgtagg taataaaaaa gcattaaccg aattccaaga tagattcaat acgtatatta
     6241 ataagcaagg ctatgattta aaacgaggaa tttctagaca acttacaaaa gaaaaacatg
     6301 atcaagttag ccgttataaa caaaaaacag aatatcataa acaaatgcat atgcgctaga
     6361 agcaaataga ggattattta aagcaagaaa atgataaatt gatacaaaac taccaaaaat
     6421 cattagatac gcttaaaaag cttctgagtg tcatgtatga aattaaaact aaaaatgtag
     6481 gtggatggtt tcataaagag aagcaagaaa caggcaatat tgtaattact aaaactgatt
     6541 ttgaaaaata cactaaacaa attaaagcag cacagatgat attagatgat tatgaatgta
     6601 ttaaaagtgg gaagtcatta aaaaaagcag agaaacaaaa tgaaagttta gttaatgaat
     6661 tgactagtgt ccatatggaa aatgaaaagc tggttgaaga atttaatgat ttagcacaac
     6721 gttataatta tttgttgtca gagaatgaaa agaaagataa agaactaaat tatacgctta
     6781 agttattcaa tcaagttttt aaaatcatta aaagtatgat gaaagaagag cgttatcata
     6841 cactaataaa tcatattgat aatcatttag acaattctaa aatacgtgaa gtaatgacga
     6901 tagataacaa tgatgaacag ttctttaaga agaaatatca agcacaagaa cgagaaatca
     6961 tttttaaaga agatagagaa gatggttata cattataaaa atagatattt aaatgcattt
     7021 gtttgaggtt aattattttt taggatgaaa aataggtagc ccccctcgaa ctttttaata
     7081 tatttttata aatcttttta aaaacctttt taggggcttg ttcagcccta gagcaacaag
     7141 ggatttcaat gcctaaagga gtgtttttgc cacataaaag gagtgttttt gccacataaa
     7201 aggagtgttt ttgccacata aaaggagtgt ttttgccaca taaaaggagt gttttaaaaa
     7261 gttgtactcc ttttatggtt tgacattgat aataaagtag tttattgtga ataaaagttt
     7321 tcaaatggga gtgtatattc aaacgatact cctttaggtt cgtaataaag ggggctgtat
     7381 catgacagga gagacagttg tatataaaaa tgaaatgaat ttagttccat taaggcgatt
     7441 tacagctact gaaattaatt tattttttgc gatgtgtaat aaattaaaag agcaagatac
     7501 taatacatta cgtttgtctt ttgatgaatt aaaaaaatta agtaattata gtccagaaac
     7561 acgtaatatt aatagatttg ctaatgattt agataatgtg tataaaaaga tgttgaattt
     7621 aaccattaga tatgaagatg atgatgtaat agaaagattc gttttattca atcattatag
     7681 aatccataag cgagaacaat atctagaaat atcaacttct tcaaatttaa aacacatatt
     7741 gaattcaatt actaataatt ttacaaaatt tgaattaaaa gaaatgacta ggcttaaatc
     7801 tacatattct aaaaatatgt ttagattact taaacaatac aaacatacag gctatttaaa
     7861 aattcacatc gatgatttta aaaatcgttt agatatacct aaatcttatc gtatgactga
     7921 tattaacaaa aatgttttta aacctattat tattgaatta ggttctatat ttaataatct
     7981 tactatcaat aaaatcaaag cgaaaaaagg gcgtaaaatt gaatggatag agttcacatt
     8041 tgacgctgag aaacgcattc ataacaaacg acaacctcaa atgtccaaga tagataaatc
     8101 aagacaatat gtgaggcgtg aaaagacgcc taaatggtta gaagaacggt catatgaaaa
     8161 gcaacctcaa aaagattacg acccacaatt agagaaagaa cgagaggatt ttttaaaaca
     8221 acttgaactg aattgggaat aacgcaactt ttcgttgcga gttggttaac taaaagtatc
     8281 gtgacttttc aattatttta attatagttt gagttaagga gtgattttat gaaattagct
     8341 gaagctataa aagaacagag agaattaaaa ggatggtctc aagaggaatt agccaatata
     8401 ttaaaggttt ccagacaaag tgtttctaaa tgggaaagtg ccaaaaacta tccttcctta
     8461 gatattttga ttgctatgag cgatttattc ggaatctctt tagagcattt aattaaagga
     8521 gatgcacgtt ttaaaaaagt tattttagag ggaaattata gagagagtaa cagggtacct
     8581 tccatagttg attttcttta tgatttttgg tggcttttct ttcctgttgc cggattttta
     8641 gtttgggcca ttcattcgtt catgggttga ttttaaaatc aaaatttaat gcacatcagg
     8701 caatatgaaa aaggaaagta tttttacgac accttgaaat gtattgataa gaatagaaga
     8761 gtttacaaaa ggcaatatga aatatatact aaaagtaaca agaatttcgt ttgtaaacgc
     8821 acaaaacccc gaactattcg ccgtagttcg gggttttgtg gtgaattggc tttaatcgtc
     8881 tatattattt tttatcacgt ttatggagct aataaccaaa taacgtaacg agacaaccac
     8941 tgattgccgt tgtcatgatg tgaacaagaa tttcattcat aaatcgcacc tcctctctac
     9001 gccgaattga catctgagag atagacgacc ttcacattat aacaaatctc tccttccatg
     9061 aaataacatg aatattaata aatgttgtta tatattaaag ataaataaat ataagggtgg
     9121 gattgataat gtttggcgat caaagacaag aagctacaaa atatgtcatt aaagaaggtt
     9181 atcaagatat ttatttcctc aacaaaaacg gggaatggta ttatttcgaa gtaagaagtg
     9241 tctggcgtgg caaacatatt attagagtta aagatggttt gttaggttgg agaaaagaaa
     9301 tagtaactga ataaagatac aaaatacttg ccaatgcaaa agaatgaaaa cgcgtcaaat
     9361 caacgatgta taaaagatgc ataaaagata atgaaagtaa aaagccataa atgccgtcat
     9421 ataggcattt atggcttttt gtttggttaa cataatcgat gattatcaga agttcaattc
     9481 acataaaaaa gcacggctaa tttatgaact tgtcgtacct ttttaattaa aattagttac
     9541 caaatagacg actccaaaac ccctttttag gttccgtttc ttcactcttt tcttctatat
     9601 cactatcatt gtcatttgga ttagctgaaa cgtcttctct ttgtgcttct tcaccttgtg
     9661 tactttcgtc gctttgactt ccagatatat ccttatattg aatctctgtt tctttagttt
     9721 cttcctgatc tcggttaata tttacaggac tagtagtata tgttttttct tgtgcatcaa
     9781 cgttttgtct agcgttagta gatgtatcaa agggataatt aaggtgtttt tctttttcta
     9841 attgattttc taatttttga atctttttat tactctctaa tgccagaact tgctgattct
     9901 caagcaattt tgatctttct tgcaactctt ttctgtaaaa ttcaattgtt gtttcatgac
     9961 gactttcttg tttttcaatt tgattattta aagtattaat ctgattttta agtatttcta
    10021 ctatttgagc atcgctttta gattcaaaat taatattatc cgactctttt ttttgtttgt
    10081 cttcagtagc actttcaaaa ccatatttct ttttattttc atttactctt tgaatgattt
    10141 tttctatatc ggtatcttct ttaataaacg aagtgttttc ctgttttatt gtctctatat
    10201 tcaatctctt aatattatta aaaatcgttt gcttactaac ccctaattct tcactcaacc
    10261 tttttacact tttcatatca tcaacccttt ataaaatgtt tataaaccct tagtaaaata
    10321 ttataagctt ataacgatta ataataaagt aatcgacaaa taaaaatata aattcgccaa
    10381 cctttttatc aagggtttgt aaagggttta tggtgtttat caaaggttta taaacctata
    10441 ttttcccttt tttaagttta ttcaaagtgc tataataacc ttaatataac aaaaacccca
    10501 actactggta atagtcgggg tttggtaata aaacgtttag aaactgttta tttatataat
    10561 tttcgatact tagattatat aatgaataat atcttagtgc aagcacctag attattaaat
    10621 aaacacaaaa aatgtaagcg ttttattacc tcttaccaaa ctaaaattcg gaaagaggtt
    10681 tttattatgt caattaaact ttacaacata aatgaggaat acagagaaaa gttttatcaa
    10741 ataccgaaag tattttttac aaatcctaaa tatatcaagt tatccaatga tgcaaaaatg
    10801 gcatggggta ttcttagaga tcgtttagat ttatcaatta aaaatggttg ggttgattct
    10861 aaaacaggta atatttattt ttattacaaa aatgaaaacc cacaaaatat attaaattgt
    10921 aaaaaagata aagtaattaa aataaagaaa gaacttaatt gaagccgaat tactactaca
    10981 agaaagacaa ggtttaaata agacaaataa actttattta gttaaaccag aagtaacaga
    11041 agatgatatt tataaaattc aaaagcaaga aaacactgtt gagagcagca atggcaagga
    11101 agtcggaaaa accgacttca agaagtcgat aaaacagaat ctaatgatac tgaacttagc
    11161 tatactgaat ctaacaatac tgaaataaat gatatgaatg acttgaatga tatagagtcc
    11221 gaaaatgaaa ttagtaatca ttcaagtcaa tgcaaggtta tttaatgcaa acaattttaa
    11281 ctgaatttga agaaacacat gcactttata tgcgccgtaa aaacatgaaa caatataata
    11341 tctttaatca atcattcaaa tgattttata acaatcaaag atacatcaaa atatttcgtt
    11401 aaatcatctg actttttaac tgatagcgat gaaaaaatca agaaattgtc agtgatctag
    11461 aaaaagattt gtatcgaaaa cgtatgttaa gttatggtgg attgcttaaa taaaaacata
    11521 aaattttaaa cttagacgat gctgaagatg gcaatttaat taatacaagt gatgaagata
    11581 aaatagcaaa tgaagaagaa aaggcacatt cgattacggc aattttgaaa agcaaaatta
    11641 ttatttaagg cattagtgat aactgatgtc tttttttatt acttttttgt aaaaaaagtg
    11701 ctgtcttatt tttgtgacaa atgctgtatg tagtgtcaca aaagtgtgac acttgagctt
    11761 tttatgaccc cacacaaaaa cattttcgaa gccttgaaat atctggcttt gccagatccc
    11821 ccattcattg atggggacaa atttccctta tgctcttacg gagattttag agttaaatta
    11881 aaatttctaa gtttttgata agaaaagccc tgcaggaatt tagaagaacg tggggaagtt
    11941 ttaaagaatt ttatgctaat ttttaatttg catgtaaatg ggcagtgtct aaaaaatagt
    12001 tattgttttt gctcaaattt ttgtttttga aaatagcata tatttatttg gctcatattt
    12061 gcgttttaaa agcgtatata agttttagat ataaaactat atgaatcacc cctaaatctt
    12121 taaaatgccc tcttaaaatt caaaataagg gcataaaaaa taaaagcccc ccccagataa
    12181 agtgaggtag ctttttcttt cgacgccgta tcgtcgatgt aattcaaaaa agttatgggc
    12241 tataaatcta catcactttt tcaagaatgt agtagcaata ttcaacgcaa attaattttt
    12301 ataactgctc ggaatatctc aagccgtttc tttaattttg aaataaaaaa atcgacgaag
    12361 gtcgattacg tttttgcaca tgtcgattta tccgacgtat aagtgcgccc ttacgggatt
    12421 taactagatt ataacgacga attttagacc tgtaaagcaa taacaattag gtctaccagg
    12481 tagataaagt gtacaaagta gaaccgaaaa agttatttat tttgaagatt tttcgtagat
    12541 ataatttgct aataaacttc ctaaaactga ataaagaaaa atagttaaac tcatgtaatc
    12601 actccataat tctgaagtgt ctccatgtct acgcatagac acgcatttat gccgagaaaa
    12661 tttattgtgc gttgagaaga acccttaact aaacttgcag acgaatgtcg gcatagcgtg
    12721 agctattaag ccgaccattc gacaagtttt gggattgtta agggttccga ggctcaacgt
    12781 caataaagca attggaataa agcacctatg attatttaaa aatataagtt ataatacatt
    12841 caaaaatatt tttgaatgag gtgtattatg attcaaacgg ttgttgctgc tgctgttctt
    12901 tatattgcta cagcagttga tttattagta attttattaa tattttttgc tagagcaaag
    12961 actagaaaag aatatagaaa tatttatgtt ggtcaatatt tagggtctat tattttaata
    13021 ttagttagtt tgtttttagc ttttgtatta aattatgttc cagaaaagtg gatattaggt
    13081 ttattgggtt taataccaat ttatcttgga attaaagtgg ctatttatga tgattgtgaa
    13141 ggagaaaaga gagctaaaaa agaattgaat gaaaaaggat tgtctaaatt agttggtacg
    13201 gttgcaattg ttacgatagc aagttgtggc gccgataata ttggtttatt tgttccgtat
    13261 tttgtgacat taagtgttac taatttatta cttactctgt ttgtcttttt aattttaatt
    13321 ttcttcttgg tgtttactgc acaaaaatta gctaatatcc caggaattgg agaaattgtt
    13381 gagaaattta gtcgttggat tatggctatc atttatatag ctttaggttt atttattatt
    13441 attgaaaatg acactattca aacaatttta ggatttatat tttaatttag ggtgtgattt
    13501 tatatgagtt atgaaaatac ttgtgatgtg atctgtgtac atgaggataa agttaacaat
    13561 gctttaagtt ttttagaaga tgataaatct aagaaattac ttaacatttt agaaaaaatt
    13621 tgtgatgaga agaaattgaa aatcatatta tctttgatta aagaagatga gttgtgtgtt
    13681 tgtgatattt ctttgatatt gaaaatgagt gttgcttcaa cttcacatca tttaaggctt
    13741 ttatataaaa atgaggtact tgatttttat aaagatggaa agatggcata ttattttatt
    13801 aaagacgatg aaataagaga gtttttctct aaaaatcagg agggtttttg aaacgagtga
    13861 aacgagtttc ttcttgtctt gatactataa aaaacaaagt tatataacat aagacgactt
    13921 atcggaagtt atctatcatc gtatattcgg agatgatata atatacaggt cgcctatctc
    13981 tcaggcgtca attcagacgc agagaggagg tgcattactt tgctaatcat tttcgttcac
    14041 atcatagcac cagtcatcag tggctgtgct gttgcgtatt atacttattg gcttagtaaa
    14101 cgcaacaaat aattaatagg cgactttata agccagcatc gaaaaaatcc ccacactatt
    14161 gcagtagtgt ggggattggt gcattaattg ttaatcattt tcgttatcta gattataaca
    14221 ctggttagta gaggaatgca aaaagataat attttaagta gtctttttgg atattatcat
    14281 atgatatatt tatgtaaatt gattttttat taaaggagca tatatgagta atactaaaat
    14341 taaatatcaa atttttattt catcaactta tttagattta atagaagagc gtcaagcagt
    14401 agtagaagca gttttaaaca gtaataatat tccagcaggt atggaacttt ttaactcaag
    14461 tagtaaaagc caatgggaaa taataacaca atggatcaat gaatcagatg cagtgatatt
    14521 attgttaggt tctagttatg gaacaattga tagtgaagaa aatattagct atacagaaat
    14581 ggagtacaat tttgctaaat ctttaggtaa acctatatat gtttttgaga tgaataaagc
    14641 atctaccgaa tccgcggaaa agtctaaaaa attagatgag tttaagacaa aagttaaaga
    14701 aaatagacta attagtccaa atattaatga tatttcggaa ttaaaaagta aagtatctca
    14761 gactttaatg caaagtgtac ctagtgaaat taaagaaaat agtggatgga taagagtaca
    14821 ggattgtggt aaaaatgtaa aaaaaattaa aaaaattgga tgctatacaa agagatttag
    14881 atacatatga ttttttgaaa gaagaacttt ataaaatatt catgtatgta aaaacttttt
    14941 atttccagca cacaccattt gatgatagtt atattgaaga tatagaaaac tacctgctaa
    15001 attatgaaaa taatccacat aaatcattca tgaaaataaa agtttatgat tataaaaact
    15061 ttttaaaaca tttaaaaaac atattgattt taattaaaca aggaaaaaag ccattagctc
    15121 aagccggtca ttttaaatta agcttttacg aagaggattt aaaattgtta caaaaaaatt
    15181 ataagactac gctagtcgat attaaaggat tgaataaaca tttttataag gaatgtgata
    15241 ggtgcttaaa agcatataat atttttattg agggtataaa taaacattta tatgaatgat
    15301 ataagtacac cctaatcata catatataat tgttgtcact ttactcgata tatgagaatg
    15361 actttaccta ataaatgaga aaagcaacgc actatattaa aatgcgttgc tttttctatt
    15421 atcgaatacc tataactaaa ctatctctag ctgtttctac aacttctgta cttattttat
    15481 ctaaaccatt tatatccata attctgtcta tctgcgcaaa taaacgatga atcagcctaa
    15541 aattcccttt tgtaatttta ataatcgtcg ttattgcctc ataatcagta aagtcttcga
    15601 gttttaaatc aaatcctaag tcttgccact tatattctaa tatatgatgc gtctcatctt
    15661 tacttagatt atcaaattca tgcgcaaaac ctatacgcga atatagttga ggataacgag
    15721 atagtttttt ctctataccc ggcataccaa taaatatcat tgctaaatta tgttcatcat
    15781 aaatagctct taattgctct aaatgttgca ctttaaggcg atcaatctca tctactataa
    15841 ttaaatcaat atatttaaac atatcactat aatgtttact atgttcatgt ccatacttat
    15901 ttacaacatg taatttttga cccaaatcaa tgattgcagt aatactatat aaatcattcc
    15961 ttaatttagt ttgtttttct gctggtgcat tataaaatat tttatccacc gatagtatgt
    16021 catcggtcgt tttactagct aaatcttccc aacctctatg gttaacttgt ttttcaatag
    16081 tatcccaatt tgtgtaatac ctagacgata aagtttttcc gacaccaggt tgaccataac
    16141 atataccaat atactgatat ttaatacaag catcacaaaa ttcagcaaag cgtttatact
    16201 ctttcgtttc aatgaaattt tgatttttag tcattacgat atctctttaa ttttttgacg
    16261 tttttagtcg tttcttgagg tgaataacca caattttttt cttccttaat taattccgtg
    16321 gtacttggac tagcaatatt ttgttttaag tgttttcttc tctgactacg agcgtgctgt
    16381 atgtctttta tatctatgga gtaatcagct atttctggac atatagcagt acaaagaaat
    16441 tcatctctat aaaacacacg tatttcagcc atatcatttg ggttataacg aatcagtaca
    16501 tattcaccta cataagcttc tagattagta ttactgtatc gaaaaccttg aaaatgaatg
    16561 ccatctgaat gaacttttct agatttaggt atttccaaca ataataaatc aagttgttct
    16621 aagctacttg gcatattagg gaaaaagtga ttactattcc aatgactgat aggcgtggta
    16681 tgaatagtac tatgttcttt ttgattataa tcttcaatta aaaagtaacg taatttttct
    16741 tcaaaattgt gaaaatttat tagattacta ggagtatcat tattgtttat atatccaggc
    16801 agttgttcta agaaagtttg attaactgtc tgaaagaatc gttctatttt tccacgacca
    16861 cgaggaacac caactttcga aaacatcaag ttaattttca aatcaatagc gacttgttcc
    16921 atatgatgtg aagtaaagtc acttccatga tctgtgtaga atttttcggg tataccacac
    16981 actggccaat tggtatcatt tttattccat attgcttggt gtagtgttaa tgctgtgttt
    17041 tgagcattgg ggggcatcaa aacttaagaa atagcctgca attgcacgac tatagtcatc
    17101 cataataata gttagccatg gtctattgat attacctttt tggtctaata taaagatatc
    17161 tagcaaagta tggtctgctt gccatatttc attgggtctc gaggattctc taatttgtat
    17221 taaatcgtac ttattttgat agtatttttc accctgatga gagaaatcaa taacagactt
    17281 aggcatcgct ttaataacac tataaatttg tttataactt ggtatatcaa aattattttc
    17341 tttacagtaa ttagtgattt tcctatgaat tgtggctata ctatttcttt tattcataag
    17401 cgcaaggcgt tcaatttcat caattatctt tggttctatt ttacgtgttc ctttatcagc
    17461 tcttgtcgca tagattagtc ctttaagtcc ttgttcttta tatgacttat tccacctata
    17521 aagggtgctt aacgcaatcc ctttactttt agaaatactt gataaagatt gttcgcctag
    17581 gataaaaggt tttataatat tgtacttttg agtagctttt ttacgtttgg cttcagaaaa
    17641 attagttaga tacttctcct tgtttttcat cttccttgtc ctccaattta ttgaggtaac
    17701 gataaattgt tgtacgtgaa acatgccact gttctgcaat tgtcttaatt ggcgtgccat
    17761 tatcataaag ggtcttaagt aagtttaaat ctttttgatt taatttttct ggtctgcctc
    17821 catatcggcc tctagcacgt gctgcaattc ggccagctga agaacgctct aaaattaaat
    17881 tacgttcaaa ttctgcaaat gctgcgaata aatgaaataa taattgtcca gttgaacttg
    17941 atttatccat tgttatattt tcttctaaac tatggaaact tacacctcgt tcgttaagct
    18001 cattaactaa tgtgattaaa tcctccatat tacgtcccaa tctatctaat ctccaaacaa
    18061 caatcgtatc tcctgacctc gcaaattcaa ttgctttatc taaaccaggt cttttacttt
    18121 ttgaaccact catatggtca ttaaatatct tttcacaacc atatgtattt aatcgatcct
    18181 cctgtaaatt taaattttgt aatccagttg aaactcttgc ataacctatt ttcaaaatac
    18241 aaacctccta tatacatctt cagtgtacca taacttaatt acaaggtctt ttatgaacat
    18301 agattttttg ttgggttttt gaacacataa tcctatgtaa ttcttactta tttagacata
    18361 aaagaagagt gtacagaaaa tggttatttt ctgtacactc tcatctttaa taatatattt
    18421 taaatgtcat taacaaaact aatttaataa gagtcaagca tagtttacat atgtattatg
    18481 tttgaaacat acctctaatt actttttact aatatcattt aaaatatctc gcaattcttc
    18541 aatttctttg ttatttaatt cttcattttt cgcaaaattc aacactaaac ttttcatatc
    18601 ccctccatac agtttattaa gaaaggtttt agcagttttc attttaatat cgtcttcttt
    18661 aatatttgat gagtaaaaat aaatattttc tgatttgtat cgttttataa tctctttttt
    18721 atatagtctt gtgattaatg ttctaatcgt tttatcacta acttctttat atttttgaat
    18781 ttcaactaca atttcattag ctgatactga ttttttatcc catattatat tcataacatc
    18841 ccattcagcc atagatattt caacttgctt attggccatt taaaacaccc attcctttta
    18901 atattttttc acttattaat tcagcatttt tcccagacgg gtttccatct gataaatgtg
    18961 tagcaaaata atacttatca tgatttgtaa ttacgtaacc tacaaaccac ccattattat
    19021 acttcccgtt tactatacct gtacctgttt tcccatacag ttcatacttt tcatttttct
    19081 taatcaataa tgaagaagat aattgattct ttgctttttt actaaaatgg ttattttgtt
    19141 ccatcatatt tttaaaaact attacttgtt caagattaga tattttcaaa ctatcttcca
    19201 tccaatagct tttataactt cccaaatttt cattaccata atttaattgc ttgagttgag
    19261 ccgcagtata gttctttggt atttgattac taatacgttc gaagtaccaa ttaactgaat
    19321 tttgcattgc tgtatttaaa tcttgttcct tattccaaga ctcgaaaaga taatgtttat
    19381 gattccatga catacgtgaa tttttatcac ttataatatg acggtcaagt ccaaacagtg
    19441 ctaaataaat tttgtaagtt gaatcaggag aatatctttt tctactttct ttttcattat
    19501 aaatatagta tttgtctttc ttcatgctgt acataacgaa agatccacta tttgaaccaa
    19561 aatttttact ttcatctaaa atttggtaat cgctttgtaa gggcttttta taattataat
    19621 cagttaagga ttgccccatt aaaaactggc tttgaattat catgataaaa aaagtaaaaa
    19681 tacaaataaa aattagaatt aattttgact gctttttcag atcggcttct tttatattaa
    19741 ttaatctatt tttgagtaat gattttttac cattaaatga atggcttaat atatttttgt
    19801 tgaaaaatga ggtttttaat acggagtcca taatagattc cgcataagtt ttaaattcat
    19861 ttttgttaat attattaagg acaaatctat cggcttctac ttcattgtca tgaattatct
    19921 ttctttttac aatatgtact aatggattgt aactcataat aatagagaag atattaaaga
    19981 taattaaatg taaagtatct ctatttttag catgagcata ttcatgcagt attatatatt
    20041 ttagtctttt atcaattaca cttttaaaat atgaactagg aatcaaaata atatatttcc
    20101 cataccaaaa agttattgga gattgaatag cctctgcttt tcgaatcaca atattttttt
    20161 tatattgatg gttgaaaagt atcgtatcta ttttattttt ttcattttcg tttagataaa
    20221 gtgactgttt ctttaaatat ttaagatata ataaggcttt caaaaattta aaacttaaaa
    20281 taataactaa aactatccaa ataactgtgc agatattatc aattgaatcc caattaaact
    20341 tatggatatc tgttgcgaac tcttgaacag gtttggtggt aattatgtta tggttcaagt
    20401 cgtgtgactt actttcaact gtgggcgctt gattattcac attattaaat tttataaaag
    20461 agaatttaat tgggataaaa ggaattaatc cagcaagcac agttagatac caaactttat
    20521 aatttaaact ataattaaaa tagcgtttta atatgtacct aaaaaatact aacaatagaa
    20581 atataaaaca aaagcttact acactcatta ttagtaattt agccattttg acaccttctt
    20641 tcaaatattt ataataaaca attgacatca atattacaat tgtaatatta ttgttttgta
    20701 aaaattacaa ctgtaatatc ggagggttta tt
//
