LOCUS       NZ_CP083501            20638 bp    DNA     circular CON 08-JAN-2024
DEFINITION  Escherichia coli strain elppa6 plasmid unnamed4, complete sequence.
ACCESSION   NZ_CP083501
VERSION     NZ_CP083501.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN21169129
            Assembly: GCF_020827615.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 20638)
  AUTHORS   Huang,Y.T.
  TITLE     Genome sequencing and analysis
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 20638)
  AUTHORS   Huang,Y.T.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-SEP-2021) Department of Computer Science and
            Information Engineering, National Chung Cheng University, No.168,
            Sec. 1, University Rd., Min-Hsiung Town, Chiayi City 621, Taiwan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: flye v. 2.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 108x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/08/2024 05:13:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,016
            CDSs (total)                      :: 4,896
            Genes (coding)                    :: 4,682
            CDSs (with protein)               :: 4,682
            Genes (RNA)                       :: 120
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 88
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 214
            CDSs (without protein)            :: 214
            Pseudo Genes (ambiguous residues) :: 0 of 214
            Pseudo Genes (frameshifted)       :: 91 of 214
            Pseudo Genes (incomplete)         :: 129 of 214
            Pseudo Genes (internal stop)      :: 45 of 214
            Pseudo Genes (multiple problems)  :: 49 of 214
            Pseudo Genes (short protein)      :: 2 of 214
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP083501.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..20638
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="elppa6"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="unnamed4"
                     /geo_loc_name="Taiwan"
                     /lat_lon="24 N 120 E"
                     /collection_date="2019-01"
                     /collected_by="National Chung Cheng University"
     gene            join(<19912..20638,1..>5)
                     /locus_tag="K9U09_RS24230"
                     /old_locus_tag="K9U09_24250"
                     /pseudo=""
     CDS             join(<19912..20638,1..>5)
                     /locus_tag="K9U09_RS24230"
                     /old_locus_tag="K9U09_24250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138014.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /name="Tn3 family transposase"
     gene            complement(456..650)
                     /locus_tag="K9U09_RS24235"
                     /old_locus_tag="K9U09_24255"
     CDS             complement(456..650)
                     /locus_tag="K9U09_RS24235"
                     /old_locus_tag="K9U09_24255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_001041633.1"
                     /translation="MNKQQQTALNMARFIKSQSLTLLEKLDALDADEQAAMCERLHELA
                     EELQNSIQVRFETESETGT"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            1568..2434
                     /locus_tag="K9U09_RS24240"
                     /old_locus_tag="K9U09_24260"
     CDS             1568..2434
                     /locus_tag="K9U09_RS24240"
                     /old_locus_tag="K9U09_24260"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_228596892.1"
                     /translation="MLRDFLKEKEIGGIQYVFVYPNIPKNKVDNFSKYFSNGFLSQEKV
                     CLFLDDTVFGSGKEGVLFTENYLCRKRIFEPSLSLLISDIIRMECKGRSLYVNGDCFYK
                     FSTVSGKDLQHIVNVMNEWIGEEKAQKLPGSINNVSDIEMNCAPRKEDSDERQPIVADM
                     LIKFLSSNNSFIVEWISKNFKERILDYIDSDDALNKLTFVIYGKMPSALMPFVKPEDVR
                     NFIAKNKVDFLNAIGLCGETENRANVIAGQTAAIDVCKCDDNYSEENVENKKTKEIKKG
                     GSRKIMS"
                     /name="hypothetical protein"
     gene            2443..3078
                     /locus_tag="K9U09_RS24245"
                     /old_locus_tag="K9U09_24265"
     CDS             2443..3078
                     /locus_tag="K9U09_RS24245"
                     /old_locus_tag="K9U09_24265"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_228596888.1"
                     /translation="MLRDDDSSVNNVLRFITKISLRHMWDVFNSSPFPPVYRVKYKLAY
                     DFYNAISQMLCSIDIDETDEAFELQMAASLAIFPVMVFASVVHIKDNYPITNDVLDLFI
                     ENVEVTLNACCCFYNNDSNREFFRQMSVSFVENALSRGNVLINEFIDAGVKGISITRED
                     LDLLCSEAIYATDEWIDAISKIELSENKGYIYGWRELLCTSPLDAFIG"
                     /name="hypothetical protein"
     gene            3271..4533
                     /locus_tag="K9U09_RS24250"
                     /old_locus_tag="K9U09_24270"
     CDS             3271..4533
                     /locus_tag="K9U09_RS24250"
                     /old_locus_tag="K9U09_24270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_031587700.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISEcp1 family transposase"
                     /protein_id="WP_000608644.1"
                     /translation="MINKIDFKAKNLTSNAGLFLLLENAKSNGIFDFIENDLVFDNDST
                     NKIKMNHIKTMLCGHFIGIDKLERLKLLQNDPLVNEFDISVKEPETVSRFLGNFNFKTT
                     QMFRDINFKVFKKLLTKSKLTSITIDIDSSVINVEGHQEGASKGYNPKKLGNRCYNIQF
                     AFCDELKAYVTGFVRSGNTYTANGAAEMIKEIVANIKSDDLEILFRMDSGYFDEKIIET
                     IESLGCKYLIKAKSYSTLTSQATNSSIVFVKGEEGRETTELYTKLVKWEKDRRFVVSRV
                     LKPEKERAQLSLLEGSEYDYFFFVTNTTLLSEKVVIYYEKRGNAENYIKEAKYDMAVGH
                     LLLKSFWANEAVFQMMMLSYNLFLLFKFDSLDSSEYRQQIKTFRLKYVFLAAKIIKTAR
                     YVIMKLSENYPYKGVYEKCLV"
                     /name="IS1380-like element ISEcp1 family transposase"
     gene            4789..5663
                     /gene="blaCTX-M"
                     /locus_tag="K9U09_RS24255"
                     /old_locus_tag="K9U09_24275"
                     /pseudo=""
     CDS             4789..5663
                     /gene="blaCTX-M"
                     /locus_tag="K9U09_RS24255"
                     /old_locus_tag="K9U09_24275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011091028.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="CTX-M family extended-spectrum class A
                     beta-lactamase"
                     /name="blaCTX-M"
     gene            complement(5710..>6054)
                     /locus_tag="K9U09_RS24260"
                     /old_locus_tag="K9U09_24280"
                     /pseudo=""
     CDS             complement(5710..>6054)
                     /locus_tag="K9U09_RS24260"
                     /old_locus_tag="K9U09_24280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016943399.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="WbuC family cupin fold metalloprotein"
                     /name="WbuC family cupin fold metalloprotein"
     gene            complement(6220..7300)
                     /locus_tag="K9U09_RS24265"
                     /old_locus_tag="K9U09_24285"
                     /pseudo=""
     CDS             complement(6220..7300)
                     /locus_tag="K9U09_RS24265"
                     /old_locus_tag="K9U09_24285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000100290.1"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /name="permease"
     gene            7405..7728
                     /locus_tag="K9U09_RS24270"
                     /old_locus_tag="K9U09_24290"
     CDS             7405..7728
                     /locus_tag="K9U09_RS24270"
                     /old_locus_tag="K9U09_24290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001175593.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_001175594.1"
                     /translation="MQLEEVAKALKELGHPTRLFIFKHLVKAGEQGLPVGELQKQLGIP
                     SSTLSHHISALVSVGLVTQNRESRTLMCVSQYEILEAIIEFLREECCVNSKTDVAEPAG
                     KNG"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            7889..>8209
                     /locus_tag="K9U09_RS24275"
                     /old_locus_tag="K9U09_24295"
                     /pseudo=""
     CDS             7889..>8209
                     /locus_tag="K9U09_RS24275"
                     /old_locus_tag="K9U09_24295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008783811.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /name="NAD(P)H-dependent oxidoreductase"
     gene            complement(8262..8966)
                     /locus_tag="K9U09_RS24280"
                     /old_locus_tag="K9U09_24300"
     CDS             complement(8262..8966)
                     /locus_tag="K9U09_RS24280"
                     /old_locus_tag="K9U09_24300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067834.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YISSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            <9032..>10199
                     /locus_tag="K9U09_RS24285"
                     /old_locus_tag="K9U09_24305"
                     /pseudo=""
     CDS             <9032..>10199
                     /locus_tag="K9U09_RS24285"
                     /old_locus_tag="K9U09_24305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138014.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /name="Tn3 family transposase"
     gene            complement(10518..10676)
                     /locus_tag="K9U09_RS25165"
     CDS             complement(10518..10676)
                     /locus_tag="K9U09_RS25165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_205849009.1"
                     /translation="MHEPPVQPDRCALSGNYRLESNPERHDLSPLAAAIGNWTRWIEIL
                     RVLEVVA"
                     /name="replication initiation protein"
     gene            complement(<11341..11532)
                     /locus_tag="K9U09_RS24290"
                     /old_locus_tag="K9U09_24310"
                     /pseudo=""
     CDS             complement(<11341..11532)
                     /locus_tag="K9U09_RS24290"
                     /old_locus_tag="K9U09_24310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041627.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            12449..13315
                     /locus_tag="K9U09_RS24295"
                     /old_locus_tag="K9U09_24315"
     CDS             12449..13315
                     /locus_tag="K9U09_RS24295"
                     /old_locus_tag="K9U09_24315"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_228596886.1"
                     /translation="MLRDFLKEKEIGGIQYVFVYPNIPKNKVDNFSKYFSNGFLSQEKV
                     CLFLDDTVFGSGKEGVLFTENYLCRKRIFEPSLSLLISDIIRMECKGRSLYVNGDCFYK
                     FSTVSGKDLQHIVNVMNEWIGEEKAQKLPGSINNVSDIEMNCAPRKEDSDERQPIVADM
                     LIKFLSSNNSFIVEWISKNFKERILDYIDSDDALNKLTFVIYGKMPSALMPFVKPEDVR
                     NFIAKNKVDFLNAIGLCGETENRANVIAGQTAAIDVCKCDDNYSEENVENKKTKEIKRG
                     GSRKIMS"
                     /name="hypothetical protein"
     gene            13324..13959
                     /locus_tag="K9U09_RS24300"
                     /old_locus_tag="K9U09_24320"
     CDS             13324..13959
                     /locus_tag="K9U09_RS24300"
                     /old_locus_tag="K9U09_24320"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_228596888.1"
                     /translation="MLRDDDSSVNNVLRFITKISLRHMWDVFNSSPFPPVYRVKYKLAY
                     DFYNAISQMLCSIDIDETDEAFELQMAASLAIFPVMVFASVVHIKDNYPITNDVLDLFI
                     ENVEVTLNACCCFYNNDSNREFFRQMSVSFVENALSRGNVLINEFIDAGVKGISITRED
                     LDLLCSEAIYATDEWIDAISKIELSENKGYIYGWRELLCTSPLDAFIG"
                     /name="hypothetical protein"
     gene            14152..15414
                     /locus_tag="K9U09_RS24305"
                     /old_locus_tag="K9U09_24325"
     CDS             14152..15414
                     /locus_tag="K9U09_RS24305"
                     /old_locus_tag="K9U09_24325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_031587700.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISEcp1 family transposase"
                     /protein_id="WP_228596890.1"
                     /translation="MINKIDFKAKNLTSNAGLFLLLENAKSNGIFDFIENDLVFDNDST
                     NKIKMNHIKTMLCGHFIGIDKLERLKLLQNDPLVNEFDISVKEPETVSRFLGNFNFKTT
                     QMFRDINFKVFKKLLTKSKLTSITIDIDSSVINVEGHQEGASKGYNPKKLGNRCYNIQF
                     AFCDELKAYVTGFVRSGNTYTANGAAEMIKEIVANIKSDDLEILFRMDSGYFDEKIIET
                     IESLGCKYLIKAKSYSTLTSQATNSSIVFVKGEEGRETTELYTKLVKWEKDRRFVVSRV
                     LKPEKERAQLSLLEGSEYDFFFFVTNTTLLSEKVVIYYEKRGNAENYIKEAKYDMAVGH
                     LLLKSFWANEAVFQMMMLSYNLFLLFKFDSLDSSEYRQQIKTFRLKYVFLAAKIIKTAR
                     YVIMKLSENYPYKGVYEKCLV"
                     /name="IS1380-like element ISEcp1 family transposase"
     gene            15670..16544
                     /gene="blaCTX-M"
                     /locus_tag="K9U09_RS24310"
                     /old_locus_tag="K9U09_24330"
                     /pseudo=""
     CDS             15670..16544
                     /gene="blaCTX-M"
                     /locus_tag="K9U09_RS24310"
                     /old_locus_tag="K9U09_24330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011091028.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="CTX-M family extended-spectrum class A
                     beta-lactamase"
                     /name="blaCTX-M"
     gene            complement(16591..>16935)
                     /locus_tag="K9U09_RS24315"
                     /old_locus_tag="K9U09_24335"
                     /pseudo=""
     CDS             complement(16591..>16935)
                     /locus_tag="K9U09_RS24315"
                     /old_locus_tag="K9U09_24335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016943399.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="WbuC family cupin fold metalloprotein"
                     /name="WbuC family cupin fold metalloprotein"
     gene            complement(17101..18180)
                     /locus_tag="K9U09_RS24320"
                     /old_locus_tag="K9U09_24340"
     CDS             complement(17101..18180)
                     /locus_tag="K9U09_RS24320"
                     /old_locus_tag="K9U09_24340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000100290.1"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="WP_001089727.1"
                     /translation="MNSWIPMLQDAAEMFVFLAVELSLLFIVISAGVSLIRQKVPDHKI
                     QQMMGARKGKGYLLASLLGAVTPFCSCSTIPMLRGLLSAKAGFGPTLTFLFVSPLLNPI
                     IVGLMWVTFGWKVTLLYAIIAAGVSVLSSIILDYLGFERHIVEYKNSVSGSCATKCGDS
                     EASVKTNCCTSSAKTIINLKTVKKEQNISACCPSILSEKSSESCCSSESQGNRNLTMNA
                     TSGLIKLAMKDALQQFKDVLPYLLLAILIGSFIYGFIPSEWIAAHAGADNPLAIPLSAV
                     VGIPLYIRAEAVIPLASVLMTKGMGLGALMALIIGSAGASLTEVILLKSMFRMPMIIAF
                     LTVILGMAILMGYLTQFLF"
                     /name="permease"
     gene            18285..18608
                     /locus_tag="K9U09_RS24325"
                     /old_locus_tag="K9U09_24345"
     CDS             18285..18608
                     /locus_tag="K9U09_RS24325"
                     /old_locus_tag="K9U09_24345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001175593.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_001175594.1"
                     /translation="MQLEEVAKALKELGHPTRLFIFKHLVKAGEQGLPVGELQKQLGIP
                     SSTLSHHISALVSVGLVTQNRESRTLMCVSQYEILEAIIEFLREECCVNSKTDVAEPAG
                     KNG"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            18769..>19089
                     /locus_tag="K9U09_RS24330"
                     /old_locus_tag="K9U09_24350"
                     /pseudo=""
     CDS             18769..>19089
                     /locus_tag="K9U09_RS24330"
                     /old_locus_tag="K9U09_24350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008783811.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /name="NAD(P)H-dependent oxidoreductase"
     gene            complement(19142..19846)
                     /locus_tag="K9U09_RS24335"
                     /old_locus_tag="K9U09_24355"
     CDS             complement(19142..19846)
                     /locus_tag="K9U09_RS24335"
                     /old_locus_tag="K9U09_24355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067834.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YISSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     ARG             15671..16185
                     /name="CTX-M-23"
                     /gene="CTX-M-23"
                     /gene_name="CTX-M beta-lactamase"
                     /tool="rgi"
                     /drug_class="cephalosporin"
                     /identity="100.0"
                     /coverage="58.76"
     ARG             4790..5304
                     /name="CTX-M-23"
                     /gene="CTX-M-23"
                     /gene_name="CTX-M beta-lactamase"
                     /tool="rgi"
                     /drug_class="cephalosporin"
                     /identity="100.0"
                     /coverage="58.76"
     ARG             16234..16544
                     /name="CTX-M-226"
                     /gene="CTX-M-226"
                     /gene_name="CTX-M beta-lactamase"
                     /tool="rgi"
                     /drug_class="cephalosporin"
                     /identity="100.0"
                     /coverage="35.4"
     ARG             5353..5663
                     /name="CTX-M-226"
                     /gene="CTX-M-226"
                     /gene_name="CTX-M beta-lactamase"
                     /tool="rgi"
                     /drug_class="cephalosporin"
                     /identity="100.0"
                     /coverage="35.4"
     Typing          299..383
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="96.512"
                     /coverage="100.0"
                     /evalue="3.06e-32"
     Typing          687..785
                     /name="MOB_unknown"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="6.22e-45"
     Typing          910..1165
                     /name="MOBF"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="95.367"
                     /coverage="89.0"
                     /evalue="1.22e-111"
     Typing          11180..11264
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="96.512"
                     /coverage="100.0"
                     /evalue="3.06e-32"
     Typing          11569..11667
                     /name="MOB_unknown"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="6.22e-45"
     Typing          11792..12046
                     /name="MOBF"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="94.595"
                     /coverage="89.0"
                     /evalue="2.65e-108"
     Typing          complement(2..288)
                     /name="rep_cluster_2350"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.069"
                     /coverage="100.0"
                     /evalue="1.15e-109"
     Typing          complement(10605..11169)
                     /name="rep_cluster_2350"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.662"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gacttgagcg tcgatttttg tgatgcttgt caggggggcg gagcctatgg aaaaacgcca
       61 gcggcgcggc cttttgtcct ggctttgcct ttttgctcat atgttctttc cggccttatc
      121 ccctgattct gtggataact gtgttaccgt ttttgtgtga gtcagtaccg ctcgccgcag
      181 ccgaacgacc gagcgtagcg agtcagtgag cgaggaagcg gaaaagcgcc tggacgtgca
      241 ttttctcctt acgcatctgt gcggcatttc acacccggca tggggcactt ttcatacaat
      301 ctgcactgat gccgcatggt taagccagta tacactccgc tgtcgctacg cgactgggtc
      361 agggcttcgc cccgacaccc gctgacgcgc cctggcgggc ttgtctgctg ccgaaaacgc
      421 tcgcggacaa gccgtgagcg cctccgtcag cttcgttatg ttcctgtttc actttcagtc
      481 tcaaagcgaa cctggatgct gttctggagt tcttccgcga gttcgtgcag tcgttcgcac
      541 atggccgcct gttcgtcggc atccagagca tccagttttt caagcagtgt caggctctgg
      601 cttttgataa atcgcgccat attcagcgca gtttgttgct gtttgttcac cttccgttgt
      661 tctccgtcag taccggatgt cgggtggacc ctgaccaggt ggtaattgta agacgttgcg
      721 ggcgacggta ttacaattgc acatcctgtc ctgttttttt aggacgtatc atggcacagc
      781 atatcaactg ataaataatc cctgtgcagt gcagccgctg ttgcataaaa tttcgctctg
      841 cgtcgagtgt ttcttaatca ataattccgc tgatactccg gaaaaacgcg agtctgttct
      901 catgcctgaa atgcccacac cccacgcaaa aacaattttt tgctgatttt tctttataaa
      961 tagagagtta tgacaaatta gttcttcttg ctctctttgt gatattttaa aaaagcggtg
     1021 tcggcgcggt gttgtcgctg cgccaacacc gctttttagg ggtggtactg actattttca
     1081 taaaaaacat cattttatat taggggtgct gctagcggcg cggtgtgttt tttacaggac
     1141 gcccctgggg gcgctgctag gggtgtctgt tcagatatgt agcaatgagt cagggattca
     1201 cgaactgaaa atgtccgaaa atgtgtctca tgggcaccgt atgcgcccaa accgatcgcc
     1261 attcactttc atgcatagct atgcagtgag ctgaaagcga tcctgacgca tttttccggt
     1321 tttcgcttgg taaaacatct ctttttgcgg tgttcgcggc agaatcgcgt tcagcgcgtt
     1381 ttagcggtgc gcgtaatgcg acgttatggt aaatatccaa gttttgccgt atcgcatgga
     1441 agtgcatgct attgcaatga cacaatattg ttcgttgcta aaactggctt ttggaagatg
     1501 atttgggtga tgctttatgt ctttatgcaa tagtcattta tccacagtag attaagaagg
     1561 tgataggatg ttaagagatt ttttaaaaga aaaagagatt ggtggtattc agtatgtgtt
     1621 tgtataccca aacattccaa aaaataaagt agataatttt tcaaaatatt tttctaatgg
     1681 ttttctatcg caagaaaaag tctgtctctt tcttgatgac actgtatttg gtagtgggaa
     1741 agaaggggtt ttatttacag agaactactt atgtcgaaaa agaatattcg aaccaagctt
     1801 gtcgctgtta atttcagata taataagaat ggaatgcaaa ggacgttctt tatatgttaa
     1861 tggggattgt ttttataagt ttagtactgt tagcggaaaa gacttgcagc acattgttaa
     1921 tgtgatgaat gaatggattg gcgaagaaaa agcgcaaaaa ttacccggat ctattaacaa
     1981 tgtaagtgac attgagatga attgcgcacc cagaaaagaa gatagcgatg aacgccaacc
     2041 tattgtagct gatatgttga taaaattctt atcatcaaat aatagtttta ttgttgagtg
     2101 gataagcaag aattttaaag aaagaatttt agattatatt gatagtgatg atgcgctaaa
     2161 taaattaact tttgttattt atggtaagat gccatctgct ttgatgcctt ttgttaagcc
     2221 agaagatgtt agaaacttta ttgcaaagaa caaagttgat tttttaaatg ccattggttt
     2281 atgcggggag actgaaaatc gagcaaatgt tatagctggt caaactgcag caattgatgt
     2341 ctgtaagtgc gatgataatt actcagaaga gaatgtagaa aacaaaaaaa caaaagaaat
     2401 aaaaaagggg gggagccgga aaattatgag ttagcatttt ctttgttgcg tgatgatgac
     2461 tcctctgtta ataacgtatt acgttttatt acaaaaatat ctctaagaca tatgtgggat
     2521 gtttttaact cctctccatt ccctcctgtg tatagggtaa aatataagtt agcatatgac
     2581 ttctataacg caatatcaca aatgttgtgt tcgatagaca ttgatgaaac tgatgaagcc
     2641 tttgaattgc aaatggctgc tagtttggct attttcccag taatggtgtt cgcttctgtt
     2701 gttcatataa aagataacta tccaataact aatgatgttt tagacttatt tatagagaac
     2761 gtagaggtta cacttaatgc atgctgctgc ttttataata atgatagcaa tagagagttt
     2821 tttagacaaa tgtcagtgtc ttttgttgag aatgctttat cgcgtggaaa tgttttgatt
     2881 aacgagttta ttgatgctgg ggtcaaggga atatccatta cgagagaaga tctggattta
     2941 ttatgttcag aggcaatata tgcaactgat gagtggattg atgctatatc taaaatagaa
     3001 ttatcagaaa ataaaggtta tatctacgga tggagagaat tgctgtgcac atcgccatta
     3061 gatgcattta ttggataatt tatacctaga ttctacgtca gtacttcaaa aagcataatc
     3121 aaagccttga taaatatgca ttccttcgaa attcagcttt cacccattgg gtgaaagaaa
     3181 agtgctcaaa aatatgttaa attatcagct tttatgactc gatatatggt aaaataatag
     3241 taagaaaagt agtaaaaagg ggttctaatt atgattaata aaattgattt caaagctaag
     3301 aatctaacat caaatgcagg tctttttctg ctccttgaga atgcaaaaag caatgggatt
     3361 tttgatttta ttgaaaatga cctcgtattt gataatgact caacaaataa aatcaagatg
     3421 aatcatataa agaccatgct ctgcggtcac ttcattggca ttgataagtt agaacgtcta
     3481 aagctacttc aaaatgatcc cctcgtcaac gagtttgata tttccgtaaa agaacctgaa
     3541 acagtgtcac ggtttctagg aaacttcaac ttcaagacaa cccaaatgtt tagagacatt
     3601 aattttaaag tctttaaaaa actgctcact aaaagtaaat tgacatccat tacgattgat
     3661 attgatagta gtgtaattaa cgtagaaggt catcaagaag gtgcgtcaaa aggatataat
     3721 cctaagaaac tgggaaaccg atgctacaat atccaatttg cattttgcga cgaattaaaa
     3781 gcatatgtta ccggatttgt aagaagtggc aatacttaca ctgcaaacgg tgctgcggaa
     3841 atgatcaaag aaattgttgc taacatcaaa tcagacgatt tagaaatttt atttcgaatg
     3901 gatagtggct actttgatga aaaaattatc gaaacgatag aatctcttgg atgcaaatat
     3961 ttaattaaag ccaaaagtta ttctacactc acctcacaag caacgaattc atcaattgta
     4021 ttcgttaaag gagaagaagg tagagaaact acagaactgt atacaaaatt agttaaatgg
     4081 gaaaaagaca gaagatttgt cgtatctcgc gtactgaaac cagaaaaaga aagagcacaa
     4141 ttatcacttt tagaaggttc cgaatacgac tactttttct ttgtaacaaa tactaccttg
     4201 ctttctgaaa aagtagttat atactatgaa aagcgtggta atgctgaaaa ctatatcaaa
     4261 gaagccaaat acgacatggc ggtgggtcat ctcttgctaa agtcattttg ggcgaatgaa
     4321 gccgtgtttc aaatgatgat gctttcatat aacctatttt tgttgttcaa gtttgattcc
     4381 ttggactctt cagaatacag acagcaaata aagacctttc gtttgaagta tgtatttctt
     4441 gcagcaaaaa taatcaaaac cgcaagatat gtaatcatga agttgtcgga aaactatccg
     4501 tacaagggag tgtatgaaaa atgtctggta taataagaat atcatcaata aaattgagtg
     4561 ttgctctgtg gataacttgc agagtttatt aagtatcatt gcagcaaaga tgaaatcaat
     4621 gatttatcaa aaatgattga aaggtggttg taaataatgt tacaatgtgt gagaagcagt
     4681 ctaaattctt cgtgaaatag tgatttttga agctaataaa aaacacacgt ggaatttagg
     4741 gactattcat gttgttgtta tttcgtatct tccagaataa ggaatcccat ggttaaaaaa
     4801 tcactgcgcc agttcacgct gatggcgacg gcaaccgtca cgctgttgtt aggaagtgtg
     4861 ccgctgtatg cgcaaacggc ggacgtacag caaaaacttg ccgaattaga gcggcagtcg
     4921 ggaggcagac tgggtgtggc attgattaac acagcagata attcgcaaat actttatcgt
     4981 gctgatgagc gctttgcgat gtgcagcacc agtaaagtga tggccgtggc cgcggtgctg
     5041 aagaaaagtg aaagcgaacc gaatctgtta aatcagcgag ttgagatcaa aaaatctgac
     5101 cttgttaact ataatccgat tgcggaaaag cacgtcaatg ggacgatgtc actggctgag
     5161 cttagcgcgg ccgcgctaca gtacagcgat aacgtggcga tgaataagct gattgctcac
     5221 gttggcggcc cggctagcgt caccgcgttc gcccgacagc gggagacgaa acgttccgtc
     5281 tcgaccgtac cgagccgacg ttaaacaccg ccattccggg cgatccgcgt gataccactt
     5341 cacctcgggc aatggcgcaa actctgcgga atctgacgct gggtaaagca ttgggcgaca
     5401 gccaacgggc gcagctggtg acatggatga aaggcaatac caccggtgca gcgagcattc
     5461 aggctggact gcctgcttcc tgggttgtgg gggataaaac cggcagcggt ggctatggca
     5521 ccaccaacga tatcgcggtg atctggccaa aagatcgtgc gccgctgatt ctggtcactt
     5581 acttcaccca gcctcaacct aaggcagaaa gccgtcgcga tgtattagcg tcggcggcta
     5641 aaatcgtcac cgacggtttg taatagcgga aacgggatgg ggaaactcat tccgtttttg
     5701 tttatcgcct tagacggcaa aagtgctgtc gcccacctgc gcttgcgcat accaggccat
     5761 aagctccgtg gttcctggtt ctccttccgc tggagcccag tgcgcatagt catcggcagc
     5821 cacgggttga tagccaccgt gttttacttc aaaaattatg ccaccggtat ccagcgacag
     5881 cacggcatgc caggttcctg cggccatctc cagcaccgta caggtttccc ccaatatcgc
     5941 ccgatgggtg acggtacccc gatcgtcaaa attcagcacc acgaaacgac cccttaatgg
     6001 caacagtagc tcgaaggtgt gagggtgtcg gtgcgggcgc acgtaggtcc caggtcatat
     6061 tccttccggc gtccggcatt ttaccgccag acagctcggg attcgtgata tcaccgttct
     6121 tgcagaatac ggttaacaat aaaagggcta caccgttaga accgcgccgt aagactgaag
     6181 ggattttcat attgacgcaa aaatcccttc tcataaggat taaaacaaaa attgcgttaa
     6241 atatcccata aggattgcca tacctaagat aaccgtcaga aatgcgatta tcatgggcat
     6301 tctgaacatt gatttaagca atattacttc tgtcagactc gctccagcac taccgattat
     6361 caaggccatt aaagctccga ggcccatacc tttagtcatc agaactgatg caagtggtat
     6421 tacggcctca gcacgaatat acagcggaat accaacaaca gcactgagcg gtatggctaa
     6481 tggattatct gcaccggcat gagctgcaat ccactctgaa gggataaaac cataaataaa
     6541 tgaacctatt aatatagcta acaaaagata aggcagaaca tccttaaact gttgtaaggc
     6601 atctttcatt gctaatttta ttagaccaga ggtggcattc attgtgagat ttctgttgcc
     6661 ctgactctcg ctgctgcaac aactttcaga agatttttct gatagaattg agggacaaca
     6721 cgccgatata ttttgctctt tctttactgt ctttaagtta attatggttt ttgctgatga
     6781 agtacagcaa ttcgttttta ccgaagcttc agaatcaccg cacttggtgg cgcaactacc
     6841 tgatactgaa tttttgtatt caacaatatg acgttcaaac cctaaataat ccagtataat
     6901 actggaaaga actgaaacac cggcagcgat gatcgcatac agcaaagtta ctttccagcc
     6961 aaaggtaacc cacattagtc ccacgataat gggattaagc aacggtgaaa caaaaaaaaa
     7021 agtgagtgtc ggaccaaacc ccgctttcgc agacaacaat cctcgcaaca ttggaattgt
     7081 tgagcaacta cagaaagggg taacggctcc cagcaacgag gccaacagat acccccttac
     7141 cttttctcgc ccccatcatc tgctgaattt tatgatccgg gactttttgc cttatcaggc
     7201 tcacaccggc actaatgaca ataaacagca atgaaagctc aacagccaga aaaacaaaca
     7261 tctctgcggc atcttgcaac ataggaatcc aactattcat actaaacctc ttgacagaat
     7321 ctattattct agaataatcg aaatataatt atagtcaaga tatttctggt attatcgaaa
     7381 tatcatcagg cagagggttg tcacatgcaa ctggaagaag tagctaaagc tctaaaagaa
     7441 ctgggtcacc cgacccgttt gttcatattc aaacatcttg taaaagctgg agaacaaggt
     7501 ttacctgtag gtgaattgca aaagcagctt ggcattcctt catcaacgtt aagtcatcat
     7561 atttcagccc tggtatcagt aggactcgtc acacaaaacc gggagagtcg aacgctcatg
     7621 tgcgtctctc aatatgaaat actggaagct atcatcgaat tcttacgtga agagtgctgt
     7681 gtaaacagta aaacagatgt tgcggaaccc gctggcaaaa atgggtaagt aaccggaaaa
     7741 ctcataactg tcatgattga cgaatgctgt atctacccgt gcgaagcaca cctaattaag
     7801 ccaagaatat atagagaaaa tcataaaaat taataggtta aataatatag ttcctgattt
     7861 atctgatact gcaataactg agcaaaaaat ggggataccg gcaatatctc acccacctcg
     7921 tattctaatg ctttatggct cagttcgtga gcgctcatac agtcgactgg cgacagagga
     7981 agcaggccgt ttgttaactg caatgggcgc agacgtccgt atttttaatc catctggcct
     8041 tccacttcct gatgatgcac cggaatcaca tccaaaagtt atggagttgc gtgaactggt
     8101 tcgctggtct gaaggaatgg tgtggtgctc tccggaacga catggagcga tgactggtat
     8161 tatgaaggca caaattgact ggataccatt atctgaaggt gctgttcgtg gcactgttgc
     8221 aaagttagcg atgaggcagc cttttgtctt attcaaaggc cttacatttc aaaaactctg
     8281 cttaccaggc gcatttcgcc caggggatca ccataataaa atgctgaggc ctggcctttg
     8341 cgtagtgcac gcatcacctc aatacctttg atggtggcgt aagccgtctt catggattta
     8401 aatcccagcg tggcgccgat tatccgtttc agtttgccat gatcgcattc aatcacgttg
     8461 ttccggtact taatctgtcg gtgttcaacg tcagacgggc accggccttc gcgtttgagc
     8521 agagcaagcg cgcgaccata ggcgggcgct ttatccgtgt tgatgaatcg cgggatctgc
     8581 cacttcttca cgttgttgag gattttaccc agaaaccggt atgcagcttt gctgttacga
     8641 cgggaggaga tataaaaatc gacagtgcgg ccccggctgt cgacggcccg gtacagatac
     8701 gcccagcggc cattgacctt cacgtaggtt tcatccatgt gccacgggca aagatcggaa
     8761 gggttacgcc agtaccagcg cagccgtttt tccatttcag gcgcataacg ctgaacccag
     8821 cggtaaatcg tggagtgatc gacattcact ccgcgttcag ccagcatctc ctgcagctca
     8881 cggtaactga tgccgtattt gcagtaccag cgtacggccc acagaatgat gtcacgctga
     8941 aaatgccggc ctttgaatgg gttcatgtgc agctccatca gcaaaagggg atgataagtt
     9001 tatcaccacc gactatttgc aacagtgcca cttcgacgac tacctgctgc cggccgagaa
     9061 gttcgccgca ctcaagcgcg agcaggccct gcccctggcg atcaacccga acagcgacca
     9121 gtacctggaa gagcgtttgc agctgctgga cgagcagttg gccaccgtca cccgcctggc
     9181 caaggacaac gagctgcccg atgccatcct caccgagtca gggctgaaaa tcaccccgct
     9241 ggatgcggcg gtgccggatc gggcgcaggc gctgatcgac caaaccagcc agttactgcc
     9301 gcgcatcaag atcaccgaac tgctgatgga cgtggacgac tggacgggct tcagccgcca
     9361 cttcacccac ttgaaggacg gggccgaggc caaagacagg acgttgctgc tgtccgcaat
     9421 cctcggtgat gcgatcaacc tcgggctgac caagatggcc gagtcgagcc ccggcctgac
     9481 ctacgccaag ctgtcctggc tgcaagcctg gcacatccgc gacgaaacct attcggcggc
     9541 cttggccgag ctggtcaacc accagtatcg ccacgccttt gccgcccact ggggcgacgg
     9601 cacgacctca tcctccgatg gccagcgctt ccgcgcgggt ggccggggcg agagcaccgg
     9661 gcacgtcaac ccgaagtacg gtagcgagcc gggacggctg ttctataccc atatctccga
     9721 ccagtacgcg ccgttcagca cccgcgtggt gaatgtcggc gtccgcgatt ccacctatgt
     9781 gctcgacggc ctgctgtacc acgagtccga cctgcggatc gaggagcact acaccgacac
     9841 ggccggcttc accgatcacg tctttgccct gatgcacctg ctaggcttcc gctcgcttcg
     9901 cgccgcgcat ccgcgacctc ggcgaaacca agctgtacgt gccgcagggc gtgcaagcct
     9961 acccgacgtt gcgcccgctg atcggcggca ccctgaacat caagcacgtg cgtgcccact
    10021 gggacgacat cctgcgcctg gccagctcga tcaagcaggg caccgtcacc gcctcgctga
    10081 tgctgcgcaa gctcggcagc tacccgcgcc agaacggact ggccgtggcc ctgcgcgagc
    10141 tgggccggat cgagcgcacg ctgttcatcc tggactggct gcaaagtgtt gaactgcgct
    10201 tatactaaat aataagcttg agaagctttt cttttgctgt tatctcttct ttttaagaaa
    10261 aaccgctaga gtcggcggtt tttctggttt tgttgacaat cgttgtgtga cttaatcgtg
    10321 agcgctcttt tagccaaaaa ctactaaagg atctcttgag atcctttttt tctaagcgta
    10381 atctgctgcc tgtaaacgaa aaaaccaccc tggcaggtgg tttttcgaag gttagctaat
    10441 cctggcagat tacctaaccg ggtaactggc ttggtggagc acagatacca aatgctgtcc
    10501 ttctagtgta gcctcagtta ggccaccact tcaagaactc ttaatatctc aatccacctt
    10561 gtccagttac caatggctgc tgccagtggc gataagtcgt gtctttccgg gttggactca
    10621 agacgatagt taccggataa ggcgcagcgg tcgggctgaa cggggggttc gtgcacacag
    10681 cccagcttgg agcgaacgac ctacaccgaa ctgagatacc aacagcgtga gctatgagaa
    10741 agcgccacgc ttcccgaagg gagaaaggcg gacaggtatc cggtaagcgg cagggtcgga
    10801 acaggagagc gcacgaggga gcttccaggg ggaaacgcct ggtatcttta tagtcctgtc
    10861 gggtttcgcc acctctacct tgactcgagc gtcgattttt gtgatgcttg tcaggggggc
    10921 ggagcctatg gaaaaacgcc agcggcgcgg ccttttgtcc tggctttgcc tttttgctca
    10981 tatgttcttt ccggccttat cccctgattc tgtggataac tgtgttaccg tttttgtgtg
    11041 agtcagtacc gctcgccgca gccgaacgac cgagcgtagc gagtcagtga gcgaggaagc
    11101 ggaaaagcgc ctggacgtgc attttctcct tacgcatctg tgcggcattt cacacccggc
    11161 atggggcact tttcatacaa tctgcactga tgccgcatgg ttaagccagt atacactccg
    11221 ctgtcgctac gcgactgggt cagggcttcg ccccgacacc cgctgacgcg ccctggcggg
    11281 cttgtctgct gccgaaaacg ctcgcggaca agccgtgagc gcctccgtca gcttcgtttt
    11341 tgttcctgtt tcactttcag tctcaaagcg aacctggatg ctgttctgga gttcttccgc
    11401 gagttcgtgc agtcgttcgc acatggccgc ctgttcgtcg gcatccagag catccagttt
    11461 ttcaagcagt gtcaggctct ggcttttgat aaatcgcgcc atattcagcg cagtttgttg
    11521 ctgtttgttc accttccgtt gttctccgtc agtaccggat gtcgggtgga ccctgaccag
    11581 gtggtaattg taagacgttg cgggcgacgg tattacaatt gcacatcctg tcctgttttt
    11641 ttaggacgta tcatggcaca gcatatcaac tgataaataa tccctgtgca gtgcagccgc
    11701 tgttgcataa aatttcgctc tgcgtcgagt gtttcttaat caataattcc gctgatactc
    11761 cggaaaaacg cgagtctgtt ctcatgcctg aaatgcccac accccacgca aaaacaattt
    11821 tttgctgatt tttctttata aatagagagt tatgacaaat tagttcttct tgctctcttt
    11881 gtgatattta aaaaagcggt gtcggcgcgg tgttgcatgc gccaacaccg ctttttaggg
    11941 gtggtactga ctattttcat aaaaaacatc attttatatt aggggtgctg ctagcggcgc
    12001 ggtgtttttt tttacaggac gcccctgggg ggcgctgcta ggggtgtctg ttcagatatg
    12061 tagcaatgag tcagggattc acgaactgaa aatgtccgaa aatgtgtctc atgggcaccg
    12121 tatgcgccca aaccgatcgc cattcacttt catgcatagc tatgcagtga gctgaaagcg
    12181 atcctgacgc atttttccgg ttttcgcttg gtaaaacatc tctttttgcg gtgttcgcgg
    12241 cagaatcgcg ttcagcgcgt tttagcggtg cgcgtaatgc gacgttatgg taaatatcca
    12301 agttttgccg tatcgcatgg aagtgcatgc tattgcaatg acacaatatt gttcgttgct
    12361 aaaactggct tttggaagat gatttgggtg atgctttatg tctttatgca atagtcattt
    12421 atccacagta gattaagaag gtgataggat gttaagagat tttttaaaag aaaaagagat
    12481 tggtggtatt cagtatgtgt ttgtataccc aaacattcca aaaaataaag tagataattt
    12541 ttcaaaatat ttttctaatg gttttctatc gcaagaaaaa gtctgtctct ttcttgatga
    12601 cactgtattt ggtagtggga aagaaggggt tttatttaca gagaactact tatgtcgaaa
    12661 aagaatattc gaaccaagct tgtcgctgtt aatttcagat ataataagaa tggaatgcaa
    12721 aggacgttct ttatatgtta atggggattg tttttataag tttagtactg ttagcggaaa
    12781 agacttgcag cacattgtta atgtgatgaa tgaatggatt ggcgaagaaa aagcgcaaaa
    12841 attacccgga tctattaaca atgtaagtga cattgagatg aattgcgcac ccagaaaaga
    12901 agatagcgat gaacgccaac ctattgtagc tgatatgttg ataaaattct tatcatcaaa
    12961 taatagtttt attgttgagt ggataagcaa gaattttaaa gaaagaattt tagattatat
    13021 tgatagtgat gatgcgctaa ataaattaac ttttgttatt tatggtaaga tgccatctgc
    13081 tttgatgcct tttgttaagc cagaagatgt tagaaacttt attgcaaaga acaaagttga
    13141 ttttttaaat gccattggtt tatgcgggga gactgaaaat cgagcaaatg ttatagctgg
    13201 tcaaactgca gcaattgatg tctgtaagtg cgatgataat tactcagaag agaatgtaga
    13261 aaacaaaaaa acaaaagaaa taaaaagggg ggggagccgg aaaattatga gttagcattt
    13321 tctttgttgc gtgatgatga ctcctctgtt aataacgtat tacgttttat tacaaaaata
    13381 tctctaagac atatgtggga tgtttttaac tcctctccat tccctcctgt gtatagggta
    13441 aaatataagt tagcatatga cttctataac gcaatatcac aaatgttgtg ttcgatagac
    13501 attgatgaaa ctgatgaagc ctttgaattg caaatggctg ctagtttggc tattttccca
    13561 gtaatggtgt tcgcttctgt tgttcatata aaagataact atccaataac taatgatgtt
    13621 ttagacttat ttatagagaa cgtagaggtt acacttaatg catgctgctg cttttataat
    13681 aatgatagca atagagagtt ttttagacaa atgtcagtgt cttttgttga gaatgcttta
    13741 tcgcgtggaa atgttttgat taacgagttt attgatgctg gggtcaaggg aatatccatt
    13801 acgagagaag atctggattt attatgttca gaggcaatat atgcaactga tgagtggatt
    13861 gatgctatat ctaaaataga attatcagaa aataaaggtt atatctacgg atggagagaa
    13921 ttgctgtgca catcgccatt agatgcattt attggataat ttatacctag attctacgtc
    13981 agtacttcaa aaagcataat caaagccttg ataaatatgc attccttcga aattcagctt
    14041 tcacccattg ggtgaaagaa aagtgctcaa aaatatgtta aattatcagc ttttatgact
    14101 cgatatatgg taaaataata gtaagaaaag tagtaaaaag gggttctaat tatgattaat
    14161 aaaattgatt tcaaagctaa gaatctaaca tcaaatgcag gtctttttct gctccttgag
    14221 aatgcaaaaa gcaatgggat ttttgatttt attgaaaatg acctcgtatt tgataatgac
    14281 tcaacaaata aaatcaagat gaatcatata aagaccatgc tctgcggtca cttcattggc
    14341 attgataagt tagaacgtct aaagctactt caaaatgatc ccctcgtcaa cgagtttgat
    14401 atttccgtaa aagaacctga aacagtgtca cggtttctag gaaacttcaa cttcaagaca
    14461 acccaaatgt ttagagacat taattttaaa gtctttaaaa aactgctcac taaaagtaaa
    14521 ttgacatcca ttacgattga tattgatagt agtgtaatta acgtagaagg tcatcaagaa
    14581 ggtgcgtcaa aaggatataa tcctaagaaa ctgggaaacc gatgctacaa tatccaattt
    14641 gcattttgcg acgaattaaa agcatatgtt accggatttg taagaagtgg caatacttac
    14701 actgcaaacg gtgctgcgga aatgatcaaa gaaattgttg ctaacatcaa atcagacgat
    14761 ttagaaattt tatttcgaat ggatagtggc tactttgatg aaaaaattat cgaaacgata
    14821 gaatctcttg gatgcaaata tttaattaaa gccaaaagtt attctacact cacctcacaa
    14881 gcaacgaatt catcaattgt attcgttaaa ggagaagaag gtagagaaac tacagaactg
    14941 tatacaaaat tagttaaatg ggaaaaagac agaagatttg tcgtatctcg cgtactgaaa
    15001 ccagaaaaag aaagagcaca attatcactt ttagaaggtt ccgaatacga cttctttttc
    15061 tttgtaacaa atactacctt gctttctgaa aaagtagtta tatactatga aaagcgtggt
    15121 aatgctgaaa actatatcaa agaagccaaa tacgacatgg cggtgggtca tctcttgcta
    15181 aagtcatttt gggcgaatga agccgtgttt caaatgatga tgctttcata taacctattt
    15241 ttgttgttca agtttgattc cttggactct tcagaataca gacagcaaat aaagaccttt
    15301 cgtttgaagt atgtatttct tgcagcaaaa ataatcaaaa ccgcaagata tgtaatcatg
    15361 aagttgtcgg aaaactatcc gtacaaggga gtgtatgaaa aatgtctggt ataataagaa
    15421 tatcatcaat aaaattgagt gttgctctgt ggataacttg cagagtttat taagtatcat
    15481 tgcagcaaag atgaaatcaa tgatttatca aaaatgattg aaaggtggtt gtaaataatg
    15541 ttacaatgtg tgagaagcag tctaaattct tcgtgaaata gtgatttttg aagctaataa
    15601 aaaacacacg tggaatttag ggactattca tgttgttgtt atttcgtatc ttccagaata
    15661 aggaatccca tggttaaaaa atcactgcgc cagttcacgc tgatggcgac ggcaaccgtc
    15721 acgctgttgt taggaagtgt gccgctgtat gcgcaaacgg cggacgtaca gcaaaaactt
    15781 gccgaattag agcggcagtc gggaggcaga ctgggtgtgg cattgattaa cacagcagat
    15841 aattcgcaaa tactttatcg tgctgatgag cgctttgcga tgtgcagcac cagtaaagtg
    15901 atggccgtgg ccgcggtgct gaagaaaagt gaaagcgaac cgaatctgtt aaatcagcga
    15961 gttgagatca aaaaatctga ccttgttaac tataatccga ttgcggaaaa gcacgtcaat
    16021 gggacgatgt cactggctga gcttagcgcg gccgcgctac agtacagcga taacgtggcg
    16081 atgaataagc tgattgctca cgttggcggc ccggctagcg tcaccgcgtt cgcccgacag
    16141 cgggagacga aacgttccgt ctcgaccgta ccgagccgac gttaaacacc gccattccgg
    16201 gcgatccgcg tgataccact tcacctcggg caatggcgca aactctgcgg aatctgacgc
    16261 tgggtaaagc attgggcgac agccaacggg cgcagctggt gacatggatg aaaggcaata
    16321 ccaccggtgc agcgagcatt caggctggac tgcctgcttc ctgggttgtg ggggataaaa
    16381 ccggcagcgg tggctatggc accaccaacg atatcgcggt gatctggcca aaagatcgtg
    16441 cgccgctgat tctggtcact tacttcaccc agcctcaacc taaggcagaa agccgtcgcg
    16501 atgtattagc gtcggcggct aaaatcgtca ccgacggttt gtaatagcgg aaacgggatg
    16561 gggaaactca ttccgttttt gtttatcgcc ttagacggca aaagtgctgt cgcccacctg
    16621 cgcttgcgca taccaggcca taagctccgt ggttcctggt tctccttccg ctggagccca
    16681 gtgcgcatag tcatcggcag ccacgggttg atagccaccg tgttttactt caaaaattat
    16741 gccaccggta tccagcgaca gcacggcatg ccaggttcct gcggccatct ccagcaccgt
    16801 acaggtttcc cccaatatcg cccgatgggt gacggtaccc cgatcgtcaa aattcagcac
    16861 cacgaaacga ccccttaatg gcaacagtag ctcgaaggtg tgagggtgtc ggtgcgggcg
    16921 cacgtaggtc ccaggtcata ttccttccgg cgtccggcat tttaccgcca gacagctcgg
    16981 gattcgtgat atcaccgttc ttgcagaata cggttaacaa taaaagggct acaccgttag
    17041 aaccgcgccg taagactgaa gggattttca tattgacgca aaaatccctt ctcataagga
    17101 ttaaaacaaa aattgcgtta aatatcccat aaggattgcc atacctaaga taaccgtcag
    17161 aaatgcgatt atcatgggca ttctgaacat tgatttaagc aatattactt ctgtcagact
    17221 cgctccagca ctaccgatta tcaaggccat taaagctccg aggcccatac ctttagtcat
    17281 cagaactgat gcaagtggta ttacggcctc agcacgaata tacagcggaa taccaacaac
    17341 agcactgagc ggtatggcta atggattatc tgcaccggca tgagctgcaa tccactctga
    17401 agggataaaa ccataaataa atgaacctat taatatagct aacaaaagat aaggcagaac
    17461 atccttaaac tgttgtaagg catctttcat tgctaatttt attagaccag aggtggcatt
    17521 cattgtgaga tttctgttgc cctgactctc gctgctgcaa caactttcag aagatttttc
    17581 tgatagaatt gagggacaac acgccgatat attttgctct ttctttactg tctttaagtt
    17641 aattatggtt tttgctgatg aagtacagca attcgttttt accgaagctt cagaatcacc
    17701 gcacttggtg gcgcaactac ctgatactga atttttgtat tcaacaatat gacgttcaaa
    17761 ccctaaataa tccagtataa tactggaaag aactgaaaca ccggcagcga tgatcgcata
    17821 cagcaaagtt actttccagc caaaggtaac ccacattagt cccacgataa tgggattaag
    17881 caacggtgaa acaaacaaaa aagtgagtgt cggaccaaac cccgctttcg cagacaacaa
    17941 tcctcgcaac attggaattg ttgagcaact acagaaaggg gtaacggctc ccagcaacga
    18001 ggccaacaga taccccttac cttttctcgc ccccatcatc tgctgaattt tatgatccgg
    18061 gactttttgc cttatcaggc tcacaccggc actaatgaca ataaacagca atgaaagctc
    18121 aacagccaga aaaacaaaca tctctgcggc atcttgcaac ataggaatcc aactattcat
    18181 actaaacctc ttgacagaat ctattattct agaataatcg aaatataatt atagtcaaga
    18241 tatttctggt attatcgaaa tatcatcagg cagagggttg tcacatgcaa ctggaagaag
    18301 tagctaaagc tctaaaagaa ctgggtcacc cgacccgttt gttcatattc aaacatcttg
    18361 taaaagctgg agaacaaggt ttacctgtag gtgaattgca aaagcagctt ggcattcctt
    18421 catcaacgtt aagtcatcat atttcagccc tggtatcagt aggactcgtc acacaaaacc
    18481 gggagagtcg aacgctcatg tgcgtctctc aatatgaaat actggaagct atcatcgaat
    18541 tcttacgtga agagtgctgt gtaaacagta aaacagatgt tgcggaaccc gctggcaaaa
    18601 atgggtaagt aaccggaaaa ctcataactg tcatgattga cgaatgctgt atctacccgt
    18661 gcgaagcaca cctaattaag ccaagaatat atagagaaaa tcataaaaat taataggtta
    18721 aataatatag ttcctgattt atctgatact gcaataactg agcaaaaaat ggggataccg
    18781 gcaatatctc acccacctcg tattctaatg ctttatggct cagttcgtga gcgctcatac
    18841 agtcgactgg cgacagagga agcaggccgt ttgttaactg caatgggcgc agacgtccgt
    18901 atttttaatc catctggcct tccacttcct gatgatgcac cggaatcaca tccaaaagtt
    18961 atggagttgc gtgaactggt tcgctggtct gaaggaatgg tgtggtgctc tccggaacga
    19021 catggagcga tgactggtat tatgaaggca caaattgact ggataccatt atctgaaggt
    19081 gctgttcgtg gcactgttgc aaagttagcg atgaggcagc cttttgtctt attcaaaggc
    19141 cttacatttc aaaaactctg cttaccaggc gcatttcgcc caggggatca ccataataaa
    19201 atgctgaggc ctggcctttg cgtagtgcac gcatcacctc aatacctttg atggtggcgt
    19261 aagccgtctt catggattta aatcccagcg tggcgccgat tatccgtttc agtttgccat
    19321 gatcgcattc aatcacgttg ttccggtact taatctgtcg gtgttcaacg tcagacgggc
    19381 accggccttc gcgtttgagc agagcaagcg cgcgaccata ggcgggcgct ttatccgtgt
    19441 tgatgaatcg cgggatctgc cacttcttca cgttgttgag gattttaccc agaaaccggt
    19501 atgcagcttt gctgttacga cgggaggaga tataaaaatc gacagtgcgg ccccggctgt
    19561 cgacggcccg gtacagatac gcccagcggc cattgacctt cacgtaggtt tcatccatgt
    19621 gccacgggca aagatcggaa gggttacgcc agtaccagcg cagccgtttt tccatttcag
    19681 gcgcataacg ctgaacccag cggtaaatcg tggagtgatc gacattcact ccgcgttcag
    19741 ccagcatctc ctgcagctca cggtaactga tgccgtattt gcagtaccag cgtacggccc
    19801 acagaatgat gtcacgctga aaatgccggc ctttgaatgg gttcatgtgc agctccatca
    19861 gcaaaagggg atgataagtt tatcaccacc gactatttgc aacagtgcca cttcgacgac
    19921 tacctgctgc cggccgagaa gttcgccgca ctcaagcgcg agcaggccct gcccctggcg
    19981 atcaacccga acagcgacca gtacctggaa gagcgtttgc agctgctgga cgagcagttg
    20041 gccaccgtca cccgcctggc caaggacaac gagctgcccg atgccatcct caccgagtca
    20101 gggctgaaaa tcaccccgct ggatgcggcg gtgccggatc gggcgcaggc gctgatcgac
    20161 caaaccagcc agttactgcc gcgcatcaag atcaccgaac tgctgatgga cgtggacgac
    20221 tggacgggct tcagccgcca cttcacccac ttgaaggacg gggccgaggc caaagacagg
    20281 acgttgctgc tgtccgcaat cctcggtgat gcgatcaacc tcgggctgac caagatggcc
    20341 gagtcgagcc ccggcctgac ctacgccaag ctgtcctggc tgcaagcctg gcacatccgc
    20401 gacgaaacct attcggcggc cttggccgag ctggtcaacc accagtatcg ccacgccttt
    20461 gccgcccact ggggcgacgg cacgacctca tcctccgatg gccagcgctt ccgcgcgggt
    20521 ggccggggcg agagcaccgg gcacgtcaac ccgaagtacg gtagcgagcc gggacggctg
    20581 ttctataccc atatctccga ccagtacgcg ccgttcagca cccgcgtggt gaatgtcg
//
