LOCUS       NZ_CP082932             7462 bp    DNA     circular CON 01-NOV-2023
DEFINITION  Salmonella enterica subsp. enterica serovar London isolate N18-04674
            plasmid unnamed2, complete sequence.
ACCESSION   NZ_CP082932
VERSION     NZ_CP082932.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN20990803
            Assembly: GCF_025643195.1
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica subsp. enterica serovar London
  ORGANISM  Salmonella enterica subsp. enterica serovar London
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 7462)
  AUTHORS   Bharat,A.
  TITLE     Importation of an OXA-48-Harbouring Salmonella enterica Serovar
            London into Canada
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7462)
  AUTHORS   Bharat,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-SEP-2021) Wastewater and Antimicrobial Resistance
            Division, Public Health Agency of Canada, 1015 Arlington St,
            Winnipeg, MB R3E3R2, Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 18-JAN-2020
            Assembly Method                   :: Unicycler v. 2020-01-18
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 79.0x
            Sequencing Technology :: Illumina NextSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/01/2023 03:17:10
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,799
            CDSs (total)                      :: 4,683
            Genes (coding)                    :: 4,524
            CDSs (with protein)               :: 4,524
            Genes (RNA)                       :: 116
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 83
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 70 of 159
            Pseudo Genes (incomplete)         :: 118 of 159
            Pseudo Genes (internal stop)      :: 30 of 159
            Pseudo Genes (multiple problems)  :: 49 of 159
            Pseudo Genes (short protein)      :: 1 of 159
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP082932.1.
            Bacteria and source DNA available from Salmonella London submitted
            to Public Health Agency of Canada.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..7462
                     /organism="Salmonella enterica subsp. enterica serovar
                     London"
                     /mol_type="genomic DNA"
                     /serovar="London"
                     /isolate="N18-04674"
                     /isolation_source="stool"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:149390"
                     /plasmid="unnamed2"
                     /geo_loc_name="Canada"
                     /lat_lon="49.89 N 97.13 W"
                     /collection_date="2018"
                     /collected_by="Public Health Agency of Canada"
                     /genotype="OXA-48"
     gene            complement(102..1037)
                     /locus_tag="K6991_RS23840"
                     /old_locus_tag="K6991_23715"
     CDS             complement(102..1037)
                     /locus_tag="K6991_RS23840"
                     /old_locus_tag="K6991_23715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011666805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_001673223.1"
                     /translation="MSAALQYFDENLPHRPYHTDDLAFGLRISGKGRALLARYIQQNQP
                     HAQFWLVFDVDRVGAAIDWSDRNSPAPNVTVKNPVNGHAHLLYALNIAVRTAPDSSVKA
                     LKYAAAIERSLCEKLDADANYSGLICKNPFHLEWQVKEWREEPYSLDELADYLDLSASA
                     RRSIDKHYGMGRNCHLFEMTRKWAYRAIRQGWPAFSQWLDAVIQRVEMYNASLPVPLSP
                     PECRAIGKSIAKYTHRNFTPETFAQYVADTHTPEIQAKRGRKGGIAKGEAYDDKRFMAL
                     CMLENGYSQKAIAAMLEVSTRTIRNWKSGK"
                     /name="replication initiation protein"
     gene            complement(2350..4008)
                     /locus_tag="K6991_RS23845"
                     /old_locus_tag="K6991_23720"
     CDS             complement(2350..4008)
                     /locus_tag="K6991_RS23845"
                     /old_locus_tag="K6991_23720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007372656.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_001529697.1"
                     /translation="MKIVIVGGVAGGASAAARARRLSEDVSIVVFERGSDVSFANCGLP
                     YHIGGKIPLRQSLILKTPEDFKSRFNIDVRIRHEVMSVDPVNKMVTVKNLTSGEVYTEE
                     WDRLLLSTGAAPVVPPLPGLQEAGVFTLRNLTDMDAIQAWIEQHNIAHTTLVGGGFIGL
                     EVMEALSERGISVTLLEMGEQVMAPVDPEMASALHQEIRSHGVDLRLRTALTEVLRTET
                     GFRVALSDGGFLQTDMVILAIGVKPESSLATGAGLAVGKRGGISVNACMQTSIPDIYAV
                     GDAVETPDLVFQEPANVPLAGPANRQGRIAADNMLDRHSLYHGSQGTSICKVFSLSIGS
                     VGANEKQLKAHGTRYEKVYVHAADHASYYPGATMISLKLLFSPDTGKILGAQASGKKGV
                     DKRIDVLAVVQRAGLTVNDLEHLELTYAPPFNSARDVVNQAGMVAANVIKGDTVICHVR
                     DVLQREPGSYCLLDIRSPAELKQFGEYPDALSIPLDSLRENLDKLPEDKEIIIGCQSGL
                     RGHVAYRMLQSHGFRTYNLSGGFITWQAVTESMSQ"
                     /name="FAD-dependent oxidoreductase"
     gene            4169..4516
                     /locus_tag="K6991_RS23850"
                     /old_locus_tag="K6991_23725"
     CDS             4169..4516
                     /locus_tag="K6991_RS23850"
                     /old_locus_tag="K6991_23725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001329508.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_023144239.1"
                     /translation="MPMNEDTKRQTDMKNAALGAADVLRGLANSDRLLLMCQLSQGEAN
                     VTELEAAVGITQPTLSQQLGVMRRLKLVETRRAGKMVYYRIGDNRIMTLLNTLYDLYCP
                     QADPDKVKKQP"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            5058..5279
                     /locus_tag="K6991_RS23855"
                     /old_locus_tag="K6991_23730"
     CDS             5058..5279
                     /locus_tag="K6991_RS23855"
                     /old_locus_tag="K6991_23730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019842149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001329509.1"
                     /translation="MTKLGENIPHIIDAAVDFMASSQAFREYLKKLPPDNTIPPDLTDE
                     HVPLYIRRLEYYRLLYRPKQTESYWKKR"
                     /name="hypothetical protein"
     gene            complement(5333..5866)
                     /locus_tag="K6991_RS23860"
                     /old_locus_tag="K6991_23735"
     CDS             complement(5333..5866)
                     /locus_tag="K6991_RS23860"
                     /old_locus_tag="K6991_23735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000168767.1"
                     /translation="MASTEEKLLTLLLSVEHLQHTAMEQQKAVADSLAVARETLRGYRD
                     ISDGVAKQVRDEVRNEVQKLDVAGLIGERISHDFQRLEESVANMKVNADALNRDIATIH
                     SNIVQEYNTLKGYSWKWLGGVSVAFLVMFCVLGWGMKTILDRNYNATAAVYQKVVTLED
                     KLAEKPVTGKSRKN"
                     /name="hypothetical protein"
     gene            complement(5869..6795)
                     /locus_tag="K6991_RS23865"
                     /old_locus_tag="K6991_23740"
     CDS             complement(5869..6795)
                     /locus_tag="K6991_RS23865"
                     /old_locus_tag="K6991_23740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="WP_163497258.1"
                     /translation="MATYHLSVKFGGKGQAANHADYIERKEKYRDRQDLEYSAHGNMPE
                     WARDNPSHFWQAADQFERANGSTYRELEIALPRELTPEQRLELVQDFVRQEAGERHAWS
                     FAIHNPKASIDGGEQPHAHIMMSQRVNDGIERTPEQYFRRYNARYPDRGGAKKDSGNLT
                     PTQQKEQLRELRKRWEVKHNEHMRKHGFERGFIDCRTLKEQGIERRPEVHLGFEAAGRL
                     DDAQRHDIMQKRSEPDYSRHLEQARTVGHDIREWLDTPVKQHELVRRLQHDVAREHGFD
                     MRDRVSRQDRTAPERVKSPSRGFSMGF"
                     /name="MobA/MobL family protein"
     gene            6972..7370
                     /locus_tag="K6991_RS23870"
                     /old_locus_tag="K6991_23745"
     CDS             6972..7370
                     /locus_tag="K6991_RS23870"
                     /old_locus_tag="K6991_23745"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_112324687.1"
                     /translation="MRISNIEWLKKRLGFIRKLGEQTARQRQIIDLLDNEAGLTEQERK
                     LLHVLATAEKNDVQAQENERKQTIQKRIEGKKQRRERNHRLFLAAGLLIEAGLVDTKTG
                     ELCYKKDRILQALKEIKYDLETSPNPDA"
                     /name="hypothetical protein"
     Typing          complement(103..1037)
                     /name="Col156"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="94.023"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(5873..6795)
                     /name="MOBQ"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.351"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atcatgcgga aaacagcacc attgcagggc tgaacgggga aaaacggcaa aaaacctact
       61 gctcaaaaaa acgacagaaa ggcgctgtta tctgatatag gctattttcc gcttttccag
      121 tttcgaatgg ttcgagtaga aacctccaac atcgccgcaa tagctttctg agaatatcca
      181 ttctccagca tacatagcgc catgaaacgc ttgtcatcgt aggcttcgcc tttagcgatg
      241 ccacctttcc tgcctctctt ggcctgtatt tctggcgtgt gcgtatcagc cacatactgt
      301 gcgaaagttt ccggcgtgaa gttcctgtgc gtgtatttcg caatactctt gccaatagcc
      361 cgacattcag gcggtgaaag cggaacggga agcgatgcgt tgtacatttc aacacgctga
      421 atcacggcat caagccactg tgagaatgct ggccagccct gccgaatcgc cctgtaagcc
      481 catttgcgcg tcatttcgaa cagatggcag tttctcccca ttccgtaatg tttatcgatg
      541 ctacggcgcg ctgaggcgct caaatcgaga taatcagcca gttcatcgag ggagtagggt
      601 tcctcgcgcc actccttcac ctgccattcc aggtggaacg gatttttgca aatcagcccg
      661 ctgtagttcg cgtctgcgtc aagtttctca cacaacgagc gttcaattgc ggcagcgtat
      721 ttcagtgcct taaccgaact gtccggtgcg gttctcacgg cgatattgag tgcgtaaagc
      781 aggtgggcgt gcccgttcac aggattttta acggtgacgt tcggtgcggg tgagttccgg
      841 tcgctccagt cgatcgctgc ccccacgcgg tcaacgtcaa aaaccagcca gaactgcgca
      901 tgaggctggt tctgctggat gtaccgagca agaagcgcac gccctttgcc ggagatgcga
      961 agaccaaaag cgagatcatc cgtgtgatag ggacggtggg gtaaattttc gtcgaagtat
     1021 tgaagcgcgg cgctcatgtg ttacgattct ctccgggtta tgcgacctac acgccctctg
     1081 tatttcatgt tgaatcttgc cggatctgga catgatttca ggggcgtttg tttttcagtc
     1141 gcttacacta cacccaacgg caaatcctgt cgaaccttcc cgaaaacccg atccatttac
     1201 cataactccc gttgtacgta ccccttaaaa cgccctcagt cgctttctgg cgcaaaaaac
     1261 gcaaaaagac aagaaaacac caggccaaac cagaaaaacg cgccagaatc gtttttagag
     1321 ggctgcataa ctatgcacga aagcgatgcg cgatcgattt cgactgttcc gaagggcgaa
     1381 caggtcaaaa tgacaagttt tctcgccctg ggtggaaagt tctgcacggg gattttctgt
     1441 ttcagagctt cacgtttcgc caggacaaaa aaaaccgacc tggggtcggg gcaagaatca
     1501 gagtctgtga gaaatttttt ttagttgtgg aatgcgtcaa tgttcgcaac cgccccaaaa
     1561 taccctgagg ctgataaaaa acaactggca ctatcccgtt ccggataaaa aaaccacaaa
     1621 agtggggaat ccaagagaaa cgataggtgt caaattgagt cagaatattg acaatgaaat
     1681 agttacgcaa ataaatttag ctgcatcact tattctgatt caatactcaa taaaaaatgc
     1741 ccgcataata aaccacattt acaaagatat atatcaaacg aaacaaccaa gttcacagct
     1801 caggataaga atttttctct atgtaataga taaaacacag tttttttata aactgtaata
     1861 tatgagctgt aatattcatg tattaattgt ttttttgaaa agcatcacaa atttattttt
     1921 tacgcatact gccctattgc aaccagcaat ggttttcact tattttcaac atctcattta
     1981 atacgagtta tacttcaacc cgtttaaagt gcaacactaa ctgagtatca tttgttttcc
     2041 ttacctaccc ctggattccc aggttttttt tataactaca aaccagcaca acaaaaaaac
     2101 aaaacacaat aaaaacaatg aattatataa aactcaacga tatctttgta cggagattta
     2161 cattcaggaa cattggggtc agtttggata tagagaatta ttgtacggta agcctgtttt
     2221 ttgaacagtc cacattatcg caatagggta ccatccaggg cgttaattat ttttgtagat
     2281 ttctattcca tataatacgt tttcaatgaa tctggaagat gaggtgccat gtgtatggca
     2341 cctcatctct tattgactca ttgattccgt aaccgcctgc caagttataa agccaccact
     2401 cagattatat gtccggaagc cgtgagactg aagcatacgg tatgccacat gcccccgcag
     2461 accactctga cacccgataa taatctcttt atcttcaggc aacttatcaa gattctcccg
     2521 cagggaatca agagggatgg atagcgcgtc aggatattca ccaaattgtt tcagttccgc
     2581 aggagaacga atatcaagta aacaataact gcccggttcc cgttgtaaca catcgcggac
     2641 atgacagatg accgtatcgc ccttgataac atttgccgcc accattccag cctggttaac
     2701 gacgtccctt gcactgttga aaggcggagc ataggtcagc tccagatgct cgagatcgtt
     2761 aacggtaagc cccgcgcgct gtacgacagc caggacatcg atgcgtttat caaccccttt
     2821 tttccctgac gcctgggccc cgagaatttt accggtatcg gggctgaaca gcagtttcag
     2881 gctgatcatt gttgcccccg ggtagtaact ggcatgatca gcggcatgga cgtaaacctt
     2941 ctcgtatcgg gtaccatggg ctttcagctg cttttcattc gccccgacac tgccaatact
     3001 cagcgaaaat accttacaaa tggatgtccc ctgactgcca tggtaaaggc tgtgacgatc
     3061 gagcatatta tcagcagcaa tgcgtccctg gcggttggct ggccctgcca gaggaacatt
     3121 agcgggttcc tgaaagacaa ggtcaggtgt ttcaactgca tcccccacgg catagatgtc
     3181 agggatactt gtctgcatac aggcattgac acttatgcct ccccgtttac ccacggcgag
     3241 cccggctcct gtggcaaggc tgctctcagg ttttaccccg atggcgagaa taaccatgtc
     3301 ggtctgcaga aacccaccgt cagacagtgc aacgcggaat cccgtctctg tccgcagtac
     3361 ctcggtgagc gccgttctga gacgcagatc cacgccatga ctcctgattt cctgatgcag
     3421 ggccgatgcc atttcaggat caaccggagc cataacctgt tcccccatct ccagcagggt
     3481 cacactgatc cccctttcgc tcagtgcctc catcacttcg agcccgataa atcccccccc
     3541 gacaagcgtg gtgtgagcga tattatgttg ctcaatccac gcctggatag catccatgtc
     3601 agtaagattt cgcagtgtaa agacacccgc ttcctgtagt ccgggcaagg ggggaacaac
     3661 cggagcggca ccggtactga ggagcagacg atcccattct tcggtataga cctccccgga
     3721 ggtcagattt ttaaccgtca ccatcttatt aaccgggtct actgacatca cttcatgacg
     3781 gatacggacg tctatgttaa aacgggattt aaaatcctcc ggggttttca gaatcagcga
     3841 ctgccgtaac ggaatttttc cgcctatatg ataaggcaat ccacagttgg cgaaagagac
     3901 atcgcttccc cgctcaaaca caacaatact gacatcctct gataaccgac gagccctggc
     3961 tgcagcggat gctcccccgg caacaccacc aacaatcact attttcatta catcctctct
     4021 gttcactcgg ggcaaaatat ctgccatata taattagtta cccggtccag ctggacgctg
     4081 cagacctgaa gatcacggtg gcaaaattac gccactatca ttatactgaa caatattata
     4141 taaaaataca taatataaga aaccagcaat gcccatgaat gaagacacaa aacgtcagac
     4201 tgatatgaaa aatgcagccc tgggggcagc agatgtccta cggggactgg ccaacagcga
     4261 ccggctattg ttgatgtgtc agttaagcca gggggaagcg aatgtgaccg agctggaagc
     4321 ggcggtcggt atcactcagc cgaccctgtc tcagcagttg ggtgtcatgc gtcgcctgaa
     4381 gctggtcgag acccgacggg caggtaaaat ggtatattac cgtatcgggg ataaccgcat
     4441 catgacgttg ttgaatacct tatatgatct ctactgcccg caggcggacc ccgacaaggt
     4501 caaaaaacaa ccttaacgta caataatttt cgatatccaa actgccccca acattcacca
     4561 gcacagttag acattagcaa tgcaaaatca atgcgattcc ggtgccgtat gtcagggaga
     4621 attatgtaaa cgggggggcc ggaatcgcat tccagctcat atcattaaat acagaaaaaa
     4681 acctctgaga gcacagaggg gataaggaat atgaatactc cggtcaggat attatcctgg
     4741 cttttatata caacatgctc acaaggacaa caactagcta gttaatagat attaaaaatt
     4801 ttagagctga aaccttaaag cttgcttcca ttccatgttt tattataaac cttatcttga
     4861 aaactgaaag gaagtacggc agattaatta agttgcgtgc attcttttca cgttgtaata
     4921 caaacaagaa cacctgcgaa gttatttctc cttacatatc cccctatgcc aacgggggat
     4981 tttttctggt tcactaacgc ataaataata gtgacatact ataattcacg aaccgtgata
     5041 atatcagatc aatcatcatg acaaaattag gtgaaaatat cccacatatt atcgatgcag
     5101 ctgtagattt tatggcatca agccaggcat ttcgtgagta tctgaaaaaa cttccccctg
     5161 ataacacaat accgccagat cttactgatg agcacgtacc gttatatata cgaaggctgg
     5221 aatactatcg actgctttat cgaccaaagc agacagaatc atattggaaa aaacggtgaa
     5281 cggttcgcga aatcctttcg cgctccgtga ggcgttggac aaacgaagcg cgtcagtttt
     5341 tccggctctt acccgtgaca ggtttctccg ccagtttatc ttccagtgtc acaactttct
     5401 gatacaccgc cgctgtggcg ttgtagttcc tgtcgagtat tgttttcatt ccccatccga
     5461 gcacacagaa cataaccaga aaagccactg acaccccacc cagccatttc cagctatacc
     5521 ctttaagggt gttgtattcc tgcacgatat tgctgtgaat tgtcgcaata tccctgttca
     5581 gggcatccgc gtttaccttc atgtttgcga ctgactcttc caaccgctga aaatcatggc
     5641 tgatgcgctc acctatcagt cctgccacgt ccagcttctg cacctcattt ctgacttcat
     5701 ccctgacctg ttttgccaca ccgtcagaaa tatcccgata tccgcgaaga gtttcccttg
     5761 ccacagccag agaatcagca acagctttct gttgctccat tgcggtatgt tgcagatgct
     5821 ccaccgataa caggagcgtg agtaattttt cttctgtgct ggccatgttc agaatcccat
     5881 agaaaatcca cgtgacggtg atttaacccg ttcaggtgca gttcggtcct gtctgctcac
     5941 tctgtctctc atgtcaaagc catgctcccg cgcaacatca tgttgaagcc ttctgaccag
     6001 ttcatgttgc ttaaccggag tgtccagcca ttccctgatg tcatgcccga ccgttcgcgc
     6061 ctgttcaaga tggcgggaat agtccggttc agaccgtttt tgcatgatgt catgacgctg
     6121 ggcatcatca agccgtccag cagcttcaaa acccagatgc acttcgggac gtcgttcaat
     6181 gccctgttct ttcagcgtcc ggcagtcaat gaagcccctt tcaaagccat gctttctcat
     6241 atgttcgttg tgcttcacct cccagcgttt tcgcaattcc cgcaactgct ctttttgctg
     6301 agtgggggtc aggtttccgg aatccttttt cgcacctccc cggtcgggat acctggcgtt
     6361 atagcgccgg aaatactgtt ccggtgtacg ttcaatgcca tcattcacac gctgactcat
     6421 catgatatgc gcatgaggct gttcgccgcc gtcaatgctc gctttcggat tgtgaatggc
     6481 aaaactccag gcgtgccgtt cgccagcttc ctgacgtaca aaatcctgca ccagttcaag
     6541 gcgctgttcc ggtgtcagtt cacggggtaa tgcaatttca agttccctat aggtcgaacc
     6601 gttcgcacgt tcaaactggt cagccgcctg ccagaaatgg gaaggattat ccctggccca
     6661 ttccggcatg tttccgtgtg cggaatattc caaatcctga cggtcgcggt atttctcttt
     6721 gcgctcgatg taatcggcgt ggtttgcagc ctgccccttg ccaccaaatt taacgctgag
     6781 gtgataggtt gccacggttt cagccctctg caggagcgca ctgtttctcg acgaaggaga
     6841 gaaacatata agtgcgcttc cttctaattt tacgaattag cacggaagat accccctgca
     6901 cccgccgacc gcaagcgata tactgctcga ccacaacaca ccgcaaaaaa acaccaggga
     6961 gcaccacgaa catgcgcatc agcaacatcg aatggctgaa gaaacggctc ggattcatca
     7021 ggaagctcgg agaacagacc gcgcgacaga gacagattat tgacctgctc gacaacgaag
     7081 ccggactcac agaacaggaa cgcaaacttc tccacgtgct ggcaacagcg gaaaaaaacg
     7141 acgtacaggc acaggagaac gagcgaaaac agacgatcca gaaacgaatc gagggaaaaa
     7201 aacaacgacg ggaacgcaat caccggctct ttctcgcggc tgggctactg atcgaagcag
     7261 gactggtaga cacaaaaaca ggcgagctat gctataaaaa agacaggata ttacaggcac
     7321 ttaaggaaat taagtacgat ctggagacat ccccaaaccc agacgcgtaa gtgcctccat
     7381 ccgtgttccg gttccctggt gcttcctcgc tcattcgctc gctacgctcg gtcatgagac
     7441 tgcggcgagc actaccagca ca
//
