LOCUS       NZ_CP082268            27847 bp    DNA     circular CON 17-OCT-2023
DEFINITION  Enterococcus lactis strain E843 plasmid pE843-27, complete sequence.
ACCESSION   NZ_CP082268
VERSION     NZ_CP082268.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN20834202
            Assembly: GCF_019880345.1
KEYWORDS    RefSeq.
SOURCE      Enterococcus lactis
  ORGANISM  Enterococcus lactis
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27847)
  AUTHORS   Du,X. and Shan,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-AUG-2021) College of Veterinary Medicine, Henan
            Agricultural University, LongZiHu RD, Zhengzhou, Henan 450046, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2016; CANU v. 1.6
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 432.0x
            Sequencing Technology             :: Illumina MiSeq; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 10/17/2023 02:55:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,870
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,661
            CDSs (with protein)               :: 2,661
            Genes (RNA)                       :: 92
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 52 of 117
            Pseudo Genes (incomplete)         :: 56 of 117
            Pseudo Genes (internal stop)      :: 22 of 117
            Pseudo Genes (multiple problems)  :: 12 of 117
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP082268.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..27847
                     /organism="Enterococcus lactis"
                     /mol_type="genomic DNA"
                     /strain="E843"
                     /isolation_source="swine"
                     /db_xref="taxon:357441"
                     /plasmid="pE843-27"
                     /geo_loc_name="China: Henan"
                     /collection_date="2018"
     ARG             3..655
                     /name="tet(L)"
                     /gene="tet(L)"
                     /gene_name="major facilitator superfamily (MFS) antibiotic
                     efflux pump"
                     /tool="rgi"
                     /drug_class="tetracycline antibiotic"
                     /identity="99.08"
                     /coverage="47.38"
     ARG             27127..27845
                     /name="tet(L)"
                     /gene="tet(L)"
                     /gene_name="major facilitator superfamily (MFS) antibiotic
                     efflux pump"
                     /tool="rgi"
                     /drug_class="tetracycline antibiotic"
                     /identity="97.5"
                     /coverage="52.4"
     gene            1219..2481
                     /gene="mobV"
                     /locus_tag="K4199_RS14125"
                     /old_locus_tag="K4199_14115"
                     /pseudo=""
     CDS             1219..2481
                     /gene="mobV"
                     /locus_tag="K4199_RS14125"
                     /old_locus_tag="K4199_14115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            2726..>3064
                     /locus_tag="K4199_RS14130"
                     /old_locus_tag="K4199_14120"
                     /pseudo=""
     CDS             2726..>3064
                     /locus_tag="K4199_RS14130"
                     /old_locus_tag="K4199_14120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001611915.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(3110..3772)
                     /locus_tag="K4199_RS14135"
                     /old_locus_tag="K4199_14125"
     CDS             complement(3110..3772)
                     /locus_tag="K4199_RS14135"
                     /old_locus_tag="K4199_14125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_167844254.1"
                     /translation="MLYLKLCNRTAVGYYLRYNLSYREVQEILYDRGINVSHTTIYRWV
                     QEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWLRKKRDT
                     QAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLNNLIEQD
                     HRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLLGIPA"
                     /name="IS6 family transposase"
     gene            complement(3797..4478)
                     /locus_tag="K4199_RS14140"
                     /old_locus_tag="K4199_14130"
     CDS             complement(join(3797..4162,4164..4478))
                     /locus_tag="K4199_RS14140"
                     /old_locus_tag="K4199_14130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /ribosomal_slippage=""
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_013646119.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASPTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            4520..5197
                     /locus_tag="K4199_RS14145"
                     /old_locus_tag="K4199_14135"
     CDS             4520..5197
                     /locus_tag="K4199_RS14145"
                     /old_locus_tag="K4199_14135"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_222897099.1"
                     /translation="MIVDLKLCNRTDNSKEYVVFNPKDIKIVNQKLTKPEQSKKFVSDV
                     DIKSLEEKAIKTIAKSELIVKANNPVEAMQKLYNNDLKSAIKASFILYDLPEDKIDSSK
                     KNVTWEDLVNIEKSYNVFSYYQNNLYGSELVEPDLNNPYQENTKILDNKATQKQPALSD
                     QYKALHDKLKEPGANKQQIQEQLNKVKIEISQKTQQQLKDFAKANPDLKQPRVKKEQQA
                     LQR"
                     /name="hypothetical protein"
     gene            complement(5527..6936)
                     /gene="fexB"
                     /locus_tag="K4199_RS14150"
                     /old_locus_tag="K4199_14140"
     ARG             complement(5531..6936)
                     /name="fexB"
                     /gene="fexB"
                     /gene_name="chloramphenicol/florfenicol efflux MFS
                     transporter FexB"
                     /tool="amrfinderplus"
                     /drug_class="PHENICOL"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(7340..>7693)
                     /locus_tag="K4199_RS14530"
                     /old_locus_tag="K4199_14145"
                     /pseudo=""
     CDS             complement(7340..>7693)
                     /locus_tag="K4199_RS14530"
                     /old_locus_tag="K4199_14145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019169163.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(8047..8304)
                     /locus_tag="K4199_RS14160"
                     /old_locus_tag="K4199_14155"
     CDS             complement(8047..8304)
                     /locus_tag="K4199_RS14160"
                     /old_locus_tag="K4199_14155"
                     /inference="COORDINATES: protein motif:HMM:NF013677.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="WP_013330744.1"
                     /translation="MTKYSESFKEMIVDLANNGTKAKDLSSEYGISEAAIYKWKKLYTK
                     DSKTGVNEKQMQTLRKEIKQLKLENEILRKAAAIFAQDPL"
                     /name="transposase"
     gene            complement(8441..8971)
                     /locus_tag="K4199_RS14165"
                     /old_locus_tag="K4199_14160"
     CDS             complement(8441..8971)
                     /locus_tag="K4199_RS14165"
                     /old_locus_tag="K4199_14160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002510381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_125276271.1"
                     /translation="MDTVRDFILYLKLCNRTVTRYILKQKTLGLFFLALTPVIDLILLI
                     TTGIDLMNGATAATPHAIAAVYISVSLVFGKSMINWADDRFGYYVMKQGPKPYKPVGLA
                     YSKNYAKSWLKHLLSYIIGTGILHLIIFLINDKSRTEAMDNVIHVWTIVIIIDLIICIS
                     YFVWPPKNTESKL"
                     /name="hypothetical protein"
     gene            complement(8975..9655)
                     /locus_tag="K4199_RS14170"
                     /old_locus_tag="K4199_14165"
     CDS             complement(8975..9655)
                     /locus_tag="K4199_RS14170"
                     /old_locus_tag="K4199_14165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_013646119.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASPTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(9709..11337)
                     /gene="poxtA"
                     /locus_tag="K4199_RS14175"
                     /old_locus_tag="K4199_14170"
     ARG             complement(9713..11337)
                     /name="poxtA"
                     /gene="poxtA"
                     /gene_name="ABC-F type ribosomal protection protein PoxtA"
                     /tool="amrfinderplus"
                     /drug_class="PHENICOL/OXAZOLIDINONE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(12296..12977)
                     /locus_tag="K4199_RS14180"
                     /old_locus_tag="K4199_14175"
     CDS             complement(join(12296..12661,12663..12977))
                     /locus_tag="K4199_RS14180"
                     /old_locus_tag="K4199_14175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /ribosomal_slippage=""
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_013646119.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASPTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(<13039..13107)
                     /locus_tag="K4199_RS14185"
                     /old_locus_tag="K4199_14180"
                     /pseudo=""
     CDS             complement(<13039..13107)
                     /locus_tag="K4199_RS14185"
                     /old_locus_tag="K4199_14180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /name="IS6 family transposase"
     gene            complement(13540..13752)
                     /locus_tag="K4199_RS14190"
                     /old_locus_tag="K4199_14185"
     CDS             complement(13540..13752)
                     /locus_tag="K4199_RS14190"
                     /old_locus_tag="K4199_14185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002324171.1"
                     /translation="MIPLYRIVLIVGMELKTLKKEQLFKVKERHNQLLCSKTGTMNIEY
                     RTEYLELTNQTDFLLIRKQQEQEKN"
                     /name="hypothetical protein"
     gene            complement(13773..14624)
                     /locus_tag="K4199_RS14195"
                     /old_locus_tag="K4199_14190"
     CDS             complement(13773..14624)
                     /locus_tag="K4199_RS14195"
                     /old_locus_tag="K4199_14190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002287227.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILDL
                     TVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAGKL
                     FKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILFFVG
                     YVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKGIRSI
                     LKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDLELPMK
                     DK"
                     /name="hypothetical protein"
     gene            complement(14725..15021)
                     /locus_tag="K4199_RS14200"
                     /old_locus_tag="K4199_14195"
     CDS             complement(14725..15021)
                     /locus_tag="K4199_RS14200"
                     /old_locus_tag="K4199_14195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication control protein PrgN"
                     /protein_id="WP_000053907.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTRE
                     KTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
                     /name="replication control protein PrgN"
     gene            complement(15156..16649)
                     /locus_tag="K4199_RS14205"
                     /old_locus_tag="K4199_14200"
     CDS             complement(15156..16649)
                     /locus_tag="K4199_RS14205"
                     /old_locus_tag="K4199_14200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="WP_000947691.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSKQ
                     LMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINTFV
                     VDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVIDVA
                     KKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSMKLES
                     DQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTLSLAYY
                     SSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELCQQWVSP
                     TLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLNLSKKELA
                     SQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLSKEKRLDYS
                     TRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
                     /name="primase C-terminal domain-containing protein"
     gene            17261..18214
                     /locus_tag="K4199_RS14210"
                     /old_locus_tag="K4199_14205"
     CDS             17261..18214
                     /locus_tag="K4199_RS14210"
                     /old_locus_tag="K4199_14205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_000429439.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLFE
                     KDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGSPG
                     SEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAADYII
                     AMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQKTID
                     KYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYYEQHGD
                     IEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
                     /name="ParA family protein"
     gene            18186..18461
                     /gene="prgO"
                     /locus_tag="K4199_RS14215"
                     /old_locus_tag="K4199_14210"
     CDS             18186..18461
                     /gene="prgO"
                     /locus_tag="K4199_RS14215"
                     /old_locus_tag="K4199_14210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA segregation protein PrgO"
                     /protein_id="WP_001196543.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVDP
                     PVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
                     /name="prgO"
     gene            18689..19370
                     /locus_tag="K4199_RS14220"
                     /old_locus_tag="K4199_14215"
     CDS             join(18689..19003,19005..19370)
                     /locus_tag="K4199_RS14220"
                     /old_locus_tag="K4199_14215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /ribosomal_slippage=""
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            19498..20457
                     /locus_tag="K4199_RS14225"
                     /old_locus_tag="K4199_14220"
     CDS             19498..20457
                     /locus_tag="K4199_RS14225"
                     /old_locus_tag="K4199_14220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558064.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS1252 family transposase"
                     /protein_id="WP_000222577.1"
                     /translation="MTYTHLTTDELVMIESYYHQNIKIVKIAEYLKRSRTPIYNVINFL
                     KEGHTALEYYQQYKENKKRCGRRNIVLPKKQQSYIKEKIAQGWTPDVIIGRKEKPISCS
                     VRTLYRQFKEKVFDESTLPMKGKRKPNGHQERRGKQAFKRNIVERETDYPTFKEEFGHI
                     EGDTIVGIHHKSAVITLVERLSKIIITLKPEGRKAIDIENTLNHWFGSIPRHLFKSITF
                     DCGKEFSNWKALSNQHDIAIYFADPGTPSQRALNENSNGLLRKDGLPKNMDFNQVDQAF
                     ISSVANKRNNIPRKSLDYQTPLEVFMSYMNEDILSSLI"
                     /name="IS30-like element IS1252 family transposase"
     gene            complement(20890..21462)
                     /locus_tag="K4199_RS14230"
                     /old_locus_tag="K4199_14225"
     CDS             complement(20890..21462)
                     /locus_tag="K4199_RS14230"
                     /old_locus_tag="K4199_14225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000170424.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRDR
                     PKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTSMG
                     RMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELLTSG
                     KSYKEVEAITGFSRSTLFRIKKKIEES"
                     /name="recombinase family protein"
     gene            complement(21478..22083)
                     /locus_tag="K4199_RS14235"
                     /old_locus_tag="K4199_14230"
     CDS             complement(21478..22083)
                     /locus_tag="K4199_RS14235"
                     /old_locus_tag="K4199_14230"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="WP_000599739.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTFK
                     GLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEIIKK
                     YVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDLEIR
                     YLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
                     /name="protein adenylyltransferase Fic"
     gene            complement(22281..22962)
                     /locus_tag="K4199_RS14240"
                     /old_locus_tag="K4199_14235"
     CDS             complement(join(22281..22646,22648..22962))
                     /locus_tag="K4199_RS14240"
                     /old_locus_tag="K4199_14235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /ribosomal_slippage=""
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            <22994..23707
                     /locus_tag="K4199_RS14245"
                     /old_locus_tag="K4199_14240"
                     /pseudo=""
     CDS             <22994..23707
                     /locus_tag="K4199_RS14245"
                     /old_locus_tag="K4199_14240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /name="C40 family peptidase"
     gene            23704..24636
                     /locus_tag="K4199_RS14250"
                     /old_locus_tag="K4199_14245"
     CDS             23704..24636
                     /locus_tag="K4199_RS14250"
                     /old_locus_tag="K4199_14245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="WP_001224319.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYKVNPHKKVVIALWVLL
                     GLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKSIDN
                     RMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQLITE
                     GENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSITTNEI
                     NEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVTVSLTVE
                     YIDQQTKATQVSQFDLVLEKNGSNWKIVK"
                     /name="conjugal transfer protein"
     gene            24881..24997
                     /locus_tag="K4199_RS14255"
                     /old_locus_tag="K4199_14250"
     CDS             24881..24997
                     /locus_tag="K4199_RS14255"
                     /old_locus_tag="K4199_14250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="WP_001791010.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
                     /name="tetracycline resistance determinant leader peptide"
     gene            25013..26932
                     /gene="tet(M)"
                     /locus_tag="K4199_RS14260"
                     /old_locus_tag="K4199_14255"
     ARG             25014..26929
                     /name="tet(M)"
                     /gene="tet(M)"
                     /gene_name="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /tool="amrfinderplus"
                     /drug_class="TETRACYCLINE"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          complement(15157..16649)
                     /name="rep_cluster_185"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          1220..2478
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="95.952"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gaaagtaaca gatccttttg ttgatcccgg attagggaaa aatatacctt ttatgattgg
       61 agttctttgt gggggaatta tatttggaac agtagcaggg tttgtctcta tggttcctta
      121 tatgatgaaa gatgtttacc agctaagtac tgccgaaatc ggaagtgtaa ttattttccc
      181 tggaacaatg agtgtcatta ttttcggcta cattggtggg atacttgttg atagaagagg
      241 tcctttatac gtgttaaaca tcggagttac atttctttct gttagctttt taactgcttc
      301 ctttctttta gaaacaacat catggttcat gacaattata atcgtatttg ttttaggtgg
      361 gctttcgttc accaaaacag ttatatcaac aattgtttca agtagcttga aacagcagga
      421 agctggtgct ggaatgagtt tgcttaactt taccagcttt ttatcagagg gaacaggtat
      481 tgcaattgta ggtggtttat tatccatacc cttacttgat caaaggttgt tacctatgga
      541 agttgatcag tcaacttatc tgtatagtaa tttgttatta cttttttcag gaatcattgt
      601 cattagttgg ctggttacct tgaatgtata taaacattct caaagggatt tctaaatcgt
      661 taagggatca actttgggag agagttcaaa attgatcctt tttttataac aggaattcaa
      721 atctttttgt tccattaaag ggcgcgattg ctgaataaaa gatacgagag acctctcttg
      781 tatctttttt attttgagtg gttttgtccg ttacactaga aaaccgaaag acaataaaaa
      841 ttttattctt gctgagtctg gctttcggta agctagacaa aacggacaaa ataaaaattg
      901 gcaagggttt aaaggtggag attttttgag tgatcttctc aaaaaatact acctgtccct
      961 tgctgatttt taaacgagca cgagagcaaa accccccttt gctgaggtgg cagagggcag
     1021 gtttttttgt ttcttttttc tcgtaaaaaa aagaaaggtc ttaaaggttt tatggttttg
     1081 gtcggcactg ccgacagcct cgcagagcac acactttatg aatataaagt atagtgtgtt
     1141 atactttact tggaagtggt tgccggaaag agcgaaaatg cctcacattt gtgccaccta
     1201 aaaaggagcg atttacatat gagttatgca gtttgtagaa tgcaaaaagt gaaatcagct
     1261 ggactaaaag gcatgcaatt tcataatcaa agagagcgaa aaagtagaac gaatgatgat
     1321 attgaccatg agcgaacacg tgaaaattat gatttgaaaa atgataaaaa tattgattac
     1381 aacgaacgtg tcaaagaaat tattgaatca caaaaaacag gtacaagaaa aacgaggaaa
     1441 gatgctgttc ttgtaaatga gttgctagta acatctgacc gagatttttt tgagcaactg
     1501 gatccaggag aataaaaacg attttttgag gaaagttata aattattttc cgaacgatat
     1561 ggcaagcaaa atattgctta tgcaacagtt cataatgatg agcaaacccc tcacatgcat
     1621 ttaggtgttg tgcctatgcg tgatggaaaa ctgcaaggaa aaaatgtgtt taatcgtcaa
     1681 gaactgttat ggctacaaga taaattcccc gagcatatga aaaaacaggg ttttgagttg
     1741 aagcgtggtg aacgtggctc tgaccgtaaa catattgaga cagctaaatt taaaaaacaa
     1801 actttggaaa aagagattga ttttctagaa aaaaatttag cagttaaaaa agatgaatgg
     1861 actgcttata gcgataaagt taaatcagat ttagaagtac cagcgaaacg acacatgaaa
     1921 agtgttgaag tgccaacggg tgaaaagtcc atgtttggtt tgggaaaaga aataatgaaa
     1981 acagaaaaga aaccaaccaa aaatgttgtt atatcggagc gtgattataa aaacttagtg
     2041 actgctgcga gagataacga taggttaaaa cagcatgtta gaaatctcat gagtactgat
     2101 atggcgagag aatataaaaa attaagtaaa gaacatgggc aagttaaaga aaaatatagt
     2161 ggtcttgtag agcgatttaa tgaaaatgta aatgattata atgagttgct tgaagaaaac
     2221 aagtctttaa agtctaaaat aagcgattta aagcgtgatg tgagtttaat ctatgaaagc
     2281 actaaggaat tccttaagga acgtacagac ggcttaaaag cctttaaaaa cgtttttaag
     2341 gggtttgtag acaaggtaaa ggataaaaca gcacaattcc aagaaaaaca cgatttagaa
     2401 cctaaaaaga acgaatttga actaactcat aaccgagagg taaaaaaaga acgaagtcga
     2461 gatcagggaa tgagtttata aaataaaaaa agcacctgaa aaggtgtctt tttttgatgg
     2521 ttttgaactt gttctttctt atcttgatac atatagaaat aacgtcattt ttattttagt
     2581 tgctgaaagg tgcgttgaag tgttggtatg tatgtgtttt aaagtattga aaacccttaa
     2641 aattggttgc acagaaaaac cccatctgtt aaagttataa gtgaccaaac aaataactaa
     2701 atagatgggg gtttctttta atattatgtg tcctaatagt agcatttatt cagatgaaaa
     2761 atcaagggtt ttagtggaca agacaaaaag tggaaaagtg agaccatgga gagaaaagaa
     2821 aatcgctaat gttgattact ttgaacttct gcatattctt gaatttaaaa aggctgaaag
     2881 agtaaaagat tgtgctgaaa tattagagta taaacaaaat cgtgaaacag gcgaaagaaa
     2941 gttgtatcga gtgtggtttt gtaaatccag gctttgtcca atgtgcaact ggaggagagc
     3001 aatgaaacat ggcattcagt cacaaaaggt tgttgctgaa gttattaaac aaaagggttc
     3061 tgttgcaaag ttttaaataa agaataaaat cccttacggt atctatgatt taagctggga
     3121 ttcccaataa taccttgatt tcagtacaga ccgaaaaccc gaagagagtg ccttcttttc
     3181 gggttttctt atataatcct cgaatggctt ccatgccttt aatcgtggta gaggcagtgc
     3241 gtaaacttcg atagaattta ttgcgtctct ttactggacg atggtcttgt tcaatcaaat
     3301 tattcaggta tttaatggta cgatgttctg tcccttgata aaagccgtat tcttttagtt
     3361 tcttaaaggc acttgtaata gagggggctt tatctgtgac tacaaccttc ggttcatcaa
     3421 actgcttcac taaccgctta agaaaagcat aggctgcttg tgtgtcccgt tttttacgta
     3481 accaaatatc caaggttaaa ccatctgcat cgatggctcg atacaaataa tgccattttc
     3541 ctttaatttt gatgtacgtt tcatccattt tccatgaata aaaggatttt ttatttttct
     3601 ttttccaaat ttgatagagt agtttgccat attcttgcac ccaacgataa atcgtcgtat
     3661 gagaaacgtt aatgccacga tcatataaga tttcttgaac ttcacgatag ctaaggttat
     3721 aacgaagata gtagcccacg gcggttctgt tgcaaagttt taaataaaga ataaaatccc
     3781 ttacggtatc tatgatttaa gctgggattc ccaataatac cttgatttca gtacagaccg
     3841 aaaacccgaa gagagtgcct tcttttcggg ttttcttata taatcctcgg atggcttcca
     3901 tgcctttaat cgtgggtgag gcagtgcgta aacttcgata gaatttattg cgtctcttta
     3961 ctggacgatg gtcttgttca atcaaattat tcaggtattt aatggtacga tgttctgtcc
     4021 cttgataaaa gccgtattct tttagtttct taaaggcact tgtaatagag ggggctttat
     4081 ctgtgactac aaccttcggt tcatcaaact gcttcactaa ccgcttaaga aaagcatagg
     4141 ctgcttgtgt gtcccgtttt tttacgtaac caaatatcca aggttaaacc atctgcatcg
     4201 atggctcgat acaaataatg ccattttcct ttaattttga tgtacgtttc atccattttc
     4261 catgaataaa aggatttttt atttttcttt ttccaaattt gatagagtag tttgccatat
     4321 tcttgcaccc aacgataaat cgtcgtatga gaaacgttaa tgccacgatc atataagatt
     4381 tcttgaactt cacgatagct aaggttataa cgaagatagt agcccacggc tacaataatc
     4441 acatcctgct gaaattgctt tcctttaaaa tgattcatcg tcattcctcc tgctatcttt
     4501 ttctattatt ctaccttatt tgatagtaga tttaaaactt tgcaacagaa ccgataattc
     4561 caaagaatac gttgtattta atccaaagga tattaaaatc gttaatcaga aactaacaaa
     4621 accagaacaa agtaaaaagt ttgttagtga tgttgatata aaatccttgg aagaaaaagc
     4681 tataaaaaca atcgcaaaat ctgaactaat tgttaaagca aacaacccag ttgaagctat
     4741 gcaaaagctt tataacaatg atttaaaaag cgctataaaa gccagcttta tattatatga
     4801 tttaccagaa gataaaatcg acagcagtaa aaagaatgtt acatgggaag atttagtcaa
     4861 catagaaaaa tcatataatg tgtttagtta ttatcaaaac aacttatacg gtagtgaact
     4921 tgtagaacct gatttgaaca atccatatca ggaaaacact aagattcttg ataataaagc
     4981 cacacaaaaa caaccagcct tatcagatca atacaaagca ttgcatgata agttaaaaga
     5041 gccaggtgca aataaacaac aaatacagga acaactaaac aaagttaaaa tcgaaattag
     5101 tcaaaagacc cagcaacaat taaaagactt tgcaaaagct aacccagatt tgaagcaacc
     5161 aagagtaaaa aaagaacagc aagctttgca acgataatca taaaaagcgc ctatttatag
     5221 gcgctttttt gtattttgac gtttgagagg cgcattctaa gaccgttgtg actttacttg
     5281 ctaaattaga atgattttac ttaataaatg agaaaatgaa acgtatggaa tgctatacaa
     5341 tattatgaat tgaaaaaagt gatagttaga tagtgtacag aaactggtta ttttcttggc
     5401 taaaatgcaa aacagggctt gttaataagc cctgtttttt aaaattattt agttgttctt
     5461 gctattaaca atttagtttc tgaataatat ttaaaaacag atgtatatct gtgtaataaa
     5521 aaggttttat tgctttaaat ccctactact tatatttaaa gtaacaatta aagcaactaa
     5581 cacgatgcac gtaatggtta aaaatatatc agaatagtgc ggggcagtta aagtataaaa
     5641 aggattaaaa gatgctttaa ccccatgtct cattgacaat aaagccccta ttagtgaggc
     5701 acctgttcct gccccaagat acattgcacc ttgaaacaac cccgtaccta caccaacttg
     5761 ttctttaggt aaagcaagta ctgcaacatt attcactgga gagttaataa atgcaaaagc
     5821 gatacctatc cctaaactcc cgatagataa taatacaggt gatgcgcctg ctacgaagct
     5881 catatataaa gaagataagc ccataataat tagtccaact aataatagta ttttaggatg
     5941 cactttgtca gataatcttc ccactattgg tgaaaggatt gcaacagcga caccaccaga
     6001 aagtaatatt aagcctgcct gtccagtact taacccatta acctcaacaa ctaataatgg
     6061 aataaaaaca agcatagaga cataagcaaa cattgaaaga aatacaatga aaattgagct
     6121 tacatataaa cggttcttca atataactgg agggataaaa ggatttttaa cattaatcac
     6181 gcgatatatt aacactatta aagctatcat agatatagaa aaacttgtgg ttgtttgtat
     6241 agaaatcaaa ccatacattt ctgaaagcgt aataccaagt aaaaaaccac ctacggttaa
     6301 tcctaataat agtccaccta aaacatcaaa attttgatga ctgttattat ctggtgattc
     6361 tattttaggc attgatattt gaacacctag aactataatt aaacccagaa caaaagtgac
     6421 ccaaaataat gattgccaac ctaataattg tcctacaacg ccgccaaata ttgggcctcc
     6481 tgcagtgcca acgccaatac aaccagcaat aatacctaaa attcttcctc tctgtccagg
     6541 cggataaatt ttagatatta taacaataga tagcacaggt atggctgcca tgccagctcc
     6601 ttgaaacatt ctacccaata ctaaaataat taaattgggc gcgaatatac atattaaact
     6661 tcctatagtt aatattagaa atccgttagt aaagagtttt ttaatattta aaaaatcaga
     6721 taaacgtcca taaaagggaa ttgctataga tagaactaag gcaacaccac ttacgaccca
     6781 actaacttgc gcctcagacc cacctaattc ttttccaatc acaccgagaa caggattaac
     6841 catatctgca gtaactgaac ccactaaaac agacaagcct aagatactaa ttaacaacac
     6901 atttgatgct atattttttt cattttgatg attcatttta cagcctccta aaatttaaat
     6961 gctcatttta gaaggctaaa tcgactgctt taaccatcaa tttcacctct caattatcca
     7021 aataaaaaac ctaatcttaa gatcagactt ttgttacata aatcaatatt ttactttttt
     7081 acgtaaggat tatagtaaaa agtctggatt ttggtattct gtttaaaaaa gtacatactt
     7141 gtccctcaac tttgagatag tctgaaactt taattgtttt ataaagggta aacaccattt
     7201 ccatcatttt tatcctcctc ttatattaat ctataccaaa ataacacaaa agagtaaatt
     7261 tgtcagtttt atctctattt tgagcaaaat agagtagtaa attttaaaat tatgagttta
     7321 tttgattatt tttaatactc tatatagttt gtctagtaac atctacttcc gtaactatat
     7381 tgctaattga aaaacatttg tctaacattt ctataactca gtaataaact aaacgttttt
     7441 gagaatcttt tgcatttggt gaataaagta caggtcgtcc tttgtatact cctttttctt
     7501 tcgctacttt aatcccttgc gtttgccgac gtttactctc atttctttct tgttctgaaa
     7561 tcatctaaga caacagttag ccaaggtctt tcaagtttgt ttttttcgtt taaaacctct
     7621 atatctaaca tagtatgatc tgcttgccaa atttcattag gatggttgca ttctttaaga
     7681 tagatagcat catacttttc agcatatttt taaagacacc tttaactttg gaattagtat
     7741 agtgtttgaa ttttttaatg gtaacagaag taatgccaag taaccgcatg attttttgaa
     7801 catacttaac agaaacatta tagccttttt gtgtcaaaaa agcgtggatt ttaggcgcac
     7861 catagatgcc attatattga tggtataagg ctttgattaa aactttaaaa cgaaggagtc
     7921 tctcatttct aacagaatat ttctctttaa tacagtaata atataagctt cttggaacat
     7981 ttaatatgcg gcatagatgg ctggcattaa agatttttga atagcgttta atccaacgga
     8041 ctttagttaa agtggatctt gagcgaatat ggcggctgcc tttcttagta tttcattttc
     8101 gagtttaagt tgttttattt cttttctaag ggtttgcatt tgtttttcat taacaccggt
     8161 tttagagtct ttcgtgtata attttttcca tttataaatg gctgcttctg aaatgccata
     8221 ctcgctactt aaatccttcg cttttgtccc attattagct aaatcaacaa tcatttcttt
     8281 aaaagattca ctgtactttg tcattttaga caccttcctt agtctcatta tatttgattc
     8341 aagactctac gaaaaggcgt cctaattttc atactagcac caactcccac taattgaggt
     8401 cagttcaaaa cgtcagtatt ttcttttttt aaaattgtaa tcataattta ctttccgtat
     8461 tttttggtgg ccacacaaaa tatgaaatac aaatgattaa gtcaataata atgacaattg
     8521 tccaaacatg aataacatta tccatagctt ctgtacgact tttatcatta attaaaaaaa
     8581 taatcaaatg caaaatacct gttcctataa tgtaagaaag taaatgtttc aaccaacttt
     8641 tagcatagtt tttagagtaa gctaatccta caggtttgta aggtttgggt ccttgtttca
     8701 tcacataata tccaaatcta tcatctgccc aatttatcat gcttttccca aagacaagag
     8761 atactgaaat atagaccgca gctatagcat gaggggttgc agctgttgct ccattcatga
     8821 ggtctatacc tgttgttata agtaatatta aatctataac tggtgtaagt gctaggaaaa
     8881 atagacctag tgttttttgt tttaagatat atcttgttac ggttctgttg caaagtttta
     8941 aataaagaat aaaatccctt acggtatcta taatttaagc tgggattccc aataatacct
     9001 tgatttcagt acagaccgaa aacccgaaga gagtgccttc ttttcgggtt ttcttatata
     9061 atcctcggat ggcttccatg cctttaatcg tgggtgaggc agtgcgtaaa cttcgataga
     9121 atttattgcg tctctttact ggacgatggt cttgttcaat caaattattc aggtatttaa
     9181 tggtacgatg ttctgtccct tgataaaagc cgtattcttt tagtttctta aaggcacttg
     9241 taatagaggg ggctttatct gtgactacaa ccttcggttc atcaaactgc ttcactaacc
     9301 gcttaagaaa agcataggct gcttgtgtgt cccgtttttt acgtaaccaa atatccaagg
     9361 ttaaaccatc tgcatcgatg gctcgataca aataatgcca ttttccttta attttgatgt
     9421 acgtttcatc cattttccat gaataaaagg attttttatt tttctttttc caaatttgat
     9481 agagtagttt gccatattct tgcacccaac gataaatcgt cgtatgagaa acgttaatgc
     9541 cacgatcata taagatttct tgaacttcac gatagctaag gttataacga agatagtagc
     9601 ccacggctac aataatcaca tcctgctgaa attgctttcc tttaaaatga ttcatcgtca
     9661 ttcctcctgc tatctttttc tattattcta ccttatttga tagtagattt aaaactttgc
     9721 aacagaaccg ttgatttcat aataatactc aagcagctca cgggaatagg gttcaattcg
     9781 accgctgggc aaaataagca tacggctaat tccgatttgt tccacaaagg atgggttatg
     9841 gctaacggca ataatggttc cctcaaacaa attgaagttg ccgccaatga ttttctgcgt
     9901 ttctgggtca aggtggttgg tcggctcgtc cagtatcaaa agattggctt tctgtaatag
     9961 gattttgcaa agggcaaccc ttgctttttc tccaggggac agcacagata ctttcttgtt
    10021 tacatcgtca tcataaaaca ggaagttgct cagtacggct ctgatttgcc acggtgtata
    10081 tccttcagac tccacattgt caatgaccgt tttgttttca tcaagctgtt cgagttcctg
    10141 tgcataatat gcaatatcag ttttctggtt aaagcgaatg catccttcat ctggactgag
    10201 aatacccatc atcaatttca ataaggtgga tttaccgaca ccgttttcac ccaccacaag
    10261 aaatcgttct cttccgttaa tctgaaagga aaggttctga taaagggtgg gataccccga
    10321 atagtggaag gtgatatttt ccacctctaa gggaacttgt gccccttcac gcttggggcg
    10381 aatatccatc ttcacacgct tgtacagtcg atttctcttt tgcagctctc cacgcttttt
    10441 atcaagccgc aaggctcgct cttgacccat tcgtttgagg tgatgattgg tctgactggc
    10501 ttgttttgct ttttgtacaa aatcggaaag ctcctttatt tctttttcct gctgtacaat
    10561 cgccatttca cgaatccgct gttcctctgc atactttttc ttgtagatgt agtagtctcc
    10621 atcataaaca gatattttat gggtagcttt gttgatgtac ataattttgt tgataatccg
    10681 atttagaaaa tcaatatcat ggctgataat cagtaccgaa cccctataat tctttaagta
    10741 ttttataaca aaatcctttg tgctgacatc taaatggttg gtaggctcat ccaacaatag
    10801 aatttccggt tttgaatata gtagtctggc aaatgccatt ttggattttt gtccgcctga
    10861 aagctctctc atcggacgat gatataattc tgcatcaatg ctcattttat ctgcaaactc
    10921 caacagaatt gtttctgcct catagaagtc gaaatactcc aagcgttctt gcaatgttcc
    10981 cattcgggca agcagtgctt cctgctctgc attgactgcg gtttcaagct ttttatagat
    11041 ttcttccaat tcctgctcat actttttaat cggacgtccc tcaaaaagga aatcccaaac
    11101 ggtaatatcc tcatcttcca agacaatttc ctgtgggaga taaccaatac gggcatttcc
    11161 actggtcagt gaaccattat caagttcaag ttctcccaac agcaggcgga acaaggtggt
    11221 ctttccggct ccgttcacgc cgacaatacc gaccttatcc aaatctccga tttgaaactc
    11281 agcatcctca taaatttctt ccaacccaaa ggctaaattc atatttttac ctttcatctt
    11341 gtatcattcc tccatcgtca tacatactgc aagccatcat tttatggctt acagttttcc
    11401 ttgcttgatt atctcctgtg cggggatata ttttcttctc tgatatcatc atttaaaaaa
    11461 taaaagcaga ggtagcaata cgtcccatag acgtagccct ctgctttttc agacactatg
    11521 ccaataacat agatgaaata tagacagcaa aaggccgtag acaaaacatt gtctacggcc
    11581 acatatccaa tcattgagtt tgcttattga aaggcaacac aaataaggct cttaaatcac
    11641 aaatttctga tttaaatagc cctgcctctc aaataaacat tttatctgat tgggctccac
    11701 acaatgctct gtcttatatt gttgtgtaga gccaaaatca atgcaaaact tcccgaataa
    11761 cactgtgctc accctctctt attttatatt ttaattatag agagcttgag tgcatatgtc
    11821 aatagctcat ctaagctgct cactttacag tttgtttata gaccaagtat tgtacaactg
    11881 taaactgaat atgtaacgca aaagaggaaa cagaggggta aaatcctctg tttttctttt
    11941 gccctttttt aatatgcagg caagccataa ccatagacaa cgctactgcc gataggatag
    12001 ctatactcgt ttaataggat agtaagaaat gctcattttt ttatccccaa tactaaaaag
    12061 cgaactacag gaatcctttt aaacagctca taaattaacg gtgtcagtat cagttcaagc
    12121 cctaaagcaa gaatatagat aaatatcatc ggtaagttga ggtaactgta aagcaagtag
    12181 catacccaca caacaacagg ataatgaata atgtaaattc caaagcttgc atttgtcatg
    12241 tggttctgtt gcaaagtttt aaataaagaa taaaatccct tacggtatct atgatttaag
    12301 ctgggattcc caataatacc ttgatttcag tacagaccga aaacccgaag agagtgcctt
    12361 cttttcgggt tttcttatat aatcctcgga tggcttccat gcctttaatc gtgggtgagg
    12421 cagtgcgtaa acttcgatag aatttattgc gtctctttac tggacgatgg tcttgttcaa
    12481 tcaaattatt caggtattta atggtacgat gttctgtccc ttgataaaag ccgtattctt
    12541 ttagtttctt aaaggcactt gtaatagagg gggctttatc tgtgactaca accttcggtt
    12601 catcaaactg cttcactaac cgcttaagaa aagcataggc tgcttgtgtg tcccgttttt
    12661 ttacgtaacc aaatatccaa ggttaaacca tctgcatcga tggctcgata caaataatgc
    12721 cattttcctt taattttgat gtacgtttca tccattttcc atgaataaaa ggatttttta
    12781 tttttctttt tccaaatttg atagagtagt ttgccatatt cttgcaccca acgataaatc
    12841 gtcgtatgag aaacgttaat gccacgatca tataagattt cttgaacttc acgatagcta
    12901 aggttataac gaagatagta gcccacggct acaataatca catcctgctg aaattgcttt
    12961 cctttaaaat gattcatcgt cattcctcct gctatctttt tctattattc taccttattt
    13021 gatagtagat ttaaaacttt gcaacagaac ccccacggct acaataatca catcctgctg
    13081 aaattgcttt cctttaaaat gattcatcgt cattcctcct gctatctttt tctattattc
    13141 taccttattt gatagtagat ttaaaacttt gcaacagaac cgttcgtcac atcttcgatc
    13201 aatttctctt acgattttct catccacatt tcttattctt acttccatat taattcctcc
    13261 aatttaaaaa ggatagcgaa aaggagccta tcctttttgc tatcctacta ccctcctttt
    13321 actatccttc actatccttt cactatccta tttttaaata ttttgttccc acatttattt
    13381 ttgagaaacg taataggcac agcctattgg aacacttttt ttaaaaagtg ttcccacgtt
    13441 tccttatgct ctttacaaat aaaggctttt agagacgttc tggaatttta gattccttga
    13501 attgttccca ttcatcaatc aattggctat aagtagccat taattttttt cttgctcttg
    13561 ttgctttcga atcaacaaaa aatcagtttg attcgttaat tctaaatatt ctgttcggta
    13621 ttcaatgttc atcgtacccg ttttactaca tagtaactga ttatgacgtt ctttcacttt
    13681 gaataactgc tccttcttta aggtttttaa ctccatgcca actataagca caatcctgta
    13741 tagaggaatc attttcaaac gattctccat aattatttat ctttcattgg aagttctaaa
    13801 tcactactgt tccaaaaaat gtatggtttg ttttgacgaa tattacttcc atctaaccac
    13861 aattttccga tgccatatcg taggcttgct tcgacttcat aaaaattgta gatctctttt
    13921 cttcgatcta ttgctttcat ttcctggcca ttttttaaaa tagatctgat gcccttaaca
    13981 gtagattcat ggatactcgt gtgaacgata tccgtattga tcaattcgtc atatcttcca
    14041 aaatcaacat tgtactcata accaagaagt gtcggaatca ggtcaatttc aatttctttt
    14101 tcaattgaac gtttaataag tttcgtggat acatacccga caaaaaagag aataataccc
    14161 acttcaaaca aatacatgtg tccatttaca aagtgaataa acgtcaataa aaaatccttc
    14221 actccttttg ttgttcttcc agattgttca atttgtttta ttaaagtcgc tagaattgca
    14281 tttacaacaa ttaaatcgaa taggcttttg aaaagttttc ctgctgttaa tttttgcctg
    14341 gtaaattgca tgactaattg agtaaaaata gacaatagca tgacaaaaat caacgtcatt
    14401 agcactgtaa aaatgtctga tgctgcaatc ctattgggat catttatcaa gtaataagcc
    14461 gttccaaata ctccaatcga gtaaacggtt aaatcaagaa taagtcgtgc cccgtaacta
    14521 caaagttttc ctaatggcca taattgcaat acccaaaatt tctttcgttt gctatttctt
    14581 ttcagaggaa gccaggtgtg ttcaatccag tcgtccgatt tcatttcgat ttcttcccta
    14641 aattctttcc tttaacgttt tcctttgcta ctttagcagc gataggttgc tcaatgaacc
    14701 aattttttaa gtaaataaaa actactactg gatatacttc ttcctttttc ttaactcgtt
    14761 agctatttta tactcaatat actcctgctc taacacacac aaacaatcat atacctgatc
    14821 catagtctcc ccagaagcta aggacaaccc atgaagaaac tcaatcggca aagaagcaac
    14881 tgttttttcc ctggtaaccc aagaagacaa agtcccctgc ttaaaaccat aaagctcaca
    14941 gaacacttcc acagataatc ccaaacgacc aatgataaac acattaacag gatgtgaata
    15001 gacataattt tttaacgaca tacaacttcc tccatgatac ataagactgc atacgcagtt
    15061 ataagtatac cacctacacg tagctaggca aagggagcaa cacctacaga agtatcatag
    15121 atatattgta tagggcaatt tgcacctttt atttttcaac ctgtatctac ttcaaaaaga
    15181 ttcacttctt taagagggtt caagggggtt gataattgtc taaatgtctc ttctactaag
    15241 ctctcgttga gtccaaatac ctctgtgatc cttgttgaat aatctagtct cttttcttta
    15301 cttagttgaa taaccctcgc gaacaacgtt ttgactgaag caatgatcat tccgccattt
    15361 cttcctcgtg ttaccttgta gaagacttta ttctcctctc gtaactcatt taagatctta
    15421 tcaagtgttc gcttgggcat cgttagttgt gaagccaatt ctttttttga caggttcaaa
    15481 taaggctcac tagcaagact tttttcgctt agataagcca atagatcttc tttccattca
    15541 tttttatgac tatattttct ttgatctcgt ggctttttaa atttccacca gccacgtcgt
    15601 tgaatgaaca gatcattatt ttttaaggtt ggtgaaaccc attgctggca caattcaata
    15661 atgaattctc tgcttgctgc ttgataatta ccagaataag cactacgtac aatctttact
    15721 aattctgctt cagatagcgg ttcctgtaac cgttcgttga atgtgaacat attgtattcg
    15781 caagtatcca atgcataacc tgaagagtaa taagctaaag aaagcgtgaa aatcacatta
    15841 tttcgaccaa gacgtccttc tccgccgacg atgtttgctt tatgaagtaa catatcgaac
    15901 cacggttcat ctacttgacg aatttctttt ttctcaggaa agacaattag ttttcgttct
    15961 cgatcttctt ttgttttttg atctgattca agcttcatcg accattgaat ccagtcagca
    16021 aaagaatact gatagttcat ttctttaaaa acaatattat tttcttgtgg gaatcgagca
    16081 attccgaagt ggttacatcc tagatccact ccggacaatt tttcagccaa ctgtagacga
    16141 attgtttttg aaattttttt tgctacatcg atcaccttga aattgctttt ctttgtgaca
    16201 tagcctggtg tctttagtac aaaataaact tgataaccat gatctgattc taaaattagc
    16261 gttggcatgt agcccacttg atctaaacag gctaaaataa tttcgccttg atggttctct
    16321 tttgaatcga tatcaactac aaatgtgttg atttgactta agtttttctc agaatgacct
    16381 ttaaccactg ttcgataatc atccgcataa gtaccaaagc gataggtatt aggtgtccaa
    16441 tgcgttagtt tcttttcgtt ctctaaaata gcttcttccg aagtaatgac cataccacgc
    16501 ccaacattca ttaattgctt gctacggtac gcaaagatag caccactcct actggaatca
    16561 atatgacctg caggtttcat ggtgctgttt cgatatttgt atgtacgtaa gccgttttta
    16621 agaatagctg aataaatttc gctcaacatc gattgtaacg tcctttctca aacaaaaaga
    16681 gaacacagtt tagctttaat ctcagccata gtatgtgttc tctcttcagt gtttaagaat
    16741 atttaattta agtacactaa ataaactttc ttctgttgag ttgctcgcct ttttttggta
    16801 gaataaaggc aatcggaaaa ggtatccgat caacttttaa tataagtagt tggtagctac
    16861 ttacatattc ttgagacgag cgtgaacaca tgtcctaacc atgtgattca gaaataattg
    16921 attctgctaa aatcaattat ttccgtctct tttttttatg taatttttct gtttaaagag
    16981 taccactgct tttgctactt tgtaaatagt gaattatctg tggtttctat agaattaagt
    17041 ttacctcttt tcactctaaa ttgtcaacgc aaaacgcaca aatatatttt gatattttga
    17101 atatatctga tatactgaat atagcaaata tatttagtat atccactata ttccttataa
    17161 agtctgaatt cttatcaatt tggagtatat tagatatatc gaatatatta agtatatgaa
    17221 gtatactaaa tatatttagt ataggaaatt ggagggaact atggaaaact tacggactgc
    17281 atttaaaaca tcagataaac taggaaaagt tgtaatgctt acaggtagaa aaggcggcat
    17341 tggtaagact acagacaatg atttattagc gattgtttct agtcaacttt ttgaaaaaga
    17401 cgtgttgcta attgattatg accaacaaag aaatactact tccaacattg gatcaacgta
    17461 tcaaattact agctttgatc gatccatgtc tgcagcaatc aaaaaagggg actgggtttc
    17521 aggtattact caagtaagtc cacatttata tattatggct ggctctcctg gatctgaaga
    17581 acttaatgaa tacttgtccg aaaaatatcc tgatcgtcgt aagagatcat tggccttcat
    17641 taaaccttta gaagaattga gaaaaaattt cgattatatc tttatcgact gcccaccatc
    17701 aacagataat gtggttcgtg cattcttaac tgctgcagat tatattattg caatgcaaga
    17761 attaaaacgg tacgcaatgg aaggaacaga agattttatt aataaagttt tagttccgat
    17821 tgtcacgaat tttgaagagt ctcatcttca aatcattgga attttgcctg ttcttttctc
    17881 agtgcgacgt tcctctcaac acgcaaacta tcaaaaaaca attgataagt atggtgaatc
    17941 aaacattttt aaaagcattg ttaaaggctc ggatcggtta gaaatgtatg gtgagaatgg
    18001 tatccaatta aatgattatg tagatcgaag atggtgggct atttttgcag acatctttac
    18061 agaattagaa gaaagaattg aatactatga acaacatggt gatattgaag gatttgatta
    18121 tacacctaaa tatgctgact caatggccaa tcatatccta cctcttggaa aggagattaa
    18181 actaaatggc attattacca acgaacaaag ataagaagaa aattggtgct gaagatattt
    18241 caattaaaga tgatattaat gtcgagttag gggaacgaaa gtacactgcg aaagaaagaa
    18301 aaccagttca agtagatcct cccgtactaa aaaccattcg ggatcttagt tatgcaaaag
    18361 atattcctat gtatgaaata gtcaaacttg caatggacgc ctatgttgat actttaaacg
    18421 acgaggaacg gattatatat aatagacgat caaaagatta aaatatagta agtatactag
    18481 atatagtaaa tatatttagt atacttacta tatttttagc tttattaatc ctaatccttc
    18541 aaaatatgtg tattgtttgg gggtatacaa cattcacaaa ttttattgtt tctagttttt
    18601 actatactaa atatggttct gttgcaaagt tttaaatcta ctatcaaata aggtagaata
    18661 atagaaaaag atagcaggag gaatgacgat gaatcatttt aaaggaaagc aatttcagca
    18721 ggatgtgatt attgtagccg tgggctacta tcttcgttat aaccttagct atcgtgaagt
    18781 tcaagaaatc ttatatgatc gtggcattaa cgtttctcat acgacgattt atcgttgggt
    18841 gcaagaatat ggcaaactac tctatcaaat ttggaaaaag aaaaataaaa aatcctttta
    18901 ttcatggaaa atggatgaaa cgtacatcaa aattaaagga aaatggcatt atttgtatcg
    18961 agccatcgat gcagatggtt taaccttgga tatttggtta cgtaaaaaaa cgggacacac
    19021 aagcagccta tgcttttctt aagcggttag tgaagcagtt tgatgaaccg aaggttgtag
    19081 tcacagataa agccccctct attacaagtg cctttaagaa actaaaagaa tacggctttt
    19141 atcaagggac agaacatcgt accattaaat acctgaataa tttgattgaa caagaccatc
    19201 gtccagtaaa gagacgcaat aaattctatc gaagtttacg cactgcctct accacgatta
    19261 aaggcatgga agccattcga ggattatata agaaaacccg aaaagaaggc actctcttcg
    19321 ggttttcggt ctgtactgaa atcaaggtat tattgggaat cccagcttaa atcatagata
    19381 ccgtaaggga ttttattctt tacgccgatt gtaaaattaa gctagacaaa taaataagcc
    19441 attcgtgcta cactcaaaat gtaattccga ctaaagaaaa cataggagtg atcacgaatg
    19501 acctacaccc atcttaccac ggatgaactg gtgatgatag agtcttacta ccaccaaaac
    19561 atcaaaattg tgaaaattgc tgagtacctg aaacgatctc gaacaccgat ttataacgtc
    19621 attaatttct tgaaagaagg ccatacggcc ctcgaatact accaacagta taaagaaaat
    19681 aagaaacggt gtggcagacg aaacatcgtc ttgccaaaga aacaacagtc ctacattaaa
    19741 gaaaaaattg cccaaggctg gacgccagac gttatcattg ggcgtaaaga gaaaccaatc
    19801 agctgttccg taagaaccct ttatcgccag ttcaaggaaa aggtgttcga tgaatcgact
    19861 ttgcccatga agggtaagcg gaaaccaaat ggacatcaag aacgccgagg aaaacaggct
    19921 tttaaacgga atatcgttga aagagaaact gattacccga catttaaaga agagttcggc
    19981 catatcgaag gcgataccat tgtaggcatt catcataaga gtgctgtcat aactttggta
    20041 gaacgtctat cgaaaatcat catcaccttg aagcccgagg ggcgcaaggc gatcgatatt
    20101 gagaatactc tgaaccactg gtttggatcg attcccagac atttatttaa atccattacc
    20161 tttgattgtg ggaaagaatt ctctaattgg aaggctttaa gtaaccaaca tgacatcgct
    20221 atttatttcg ctgatccagg gactccttcg caacgagcac tgaatgaaaa ttccaatggc
    20281 ttgctgcgaa aagatggtct gccaaaaaac atggatttta atcaagtcga ccaagctttt
    20341 atctcttcag tggcgaataa gagaaacaat attccacgaa agtccttgga ttatcaaaca
    20401 cccctggaag tatttatgag ttacatgaat gaagatattt tgtctagctt aatttgacaa
    20461 atcaaattat ttaaaacttt gcaacagaac cttagcagca gtgctgattt ttatgatagt
    20521 tatttggttc ttaaatgaaa gatctaaaga caatcaacac cgtagggata tggagataaa
    20581 atcaatagag tcaatagatt atttatcgat aataacacta aaaaagccac gttcctaaac
    20641 gtgacttacg ctgaacgata tgtgttgttt ggtagacgaa caaatcgttc attataaata
    20701 tatgatggta tcctaatata gtaagcgtgg ctagcatacc tttaattact ttacctttta
    20761 cagttaccat acacattttt tgagcagaaa tcaagtaaat aaaaaaatat tatatttcac
    20821 aacatgctaa tagactcata tctagaacgc attaagtatt tacctgtctg gttcgctgag
    20881 acttcttttt taactttctt caattttctt ctttattcta aaaagcgtac tgcgactgaa
    20941 accggttata gcttcaactt ccttatacga tttacctgaa gtaagcagtt catatgcgtg
    21001 cctcttcttc ggtgtgattg ttgctttcgg acgtccttct ctgaaattag gattattctt
    21061 tcttgcaaac atttttcctt cttgggtacg ttccacaatc atatcacgtt ccatttctgc
    21121 tacactcaac aacgtccgtg tcaccattcg ccccatggac gtattttcaa tcgttcctag
    21181 attcaaaacc ttgatcgtta cgttatcatc gagtaaaggt tcaatgatct ctaatgcttc
    21241 tctcgtgtta cgagcaaatc gatcaagctt cgtaacaact atttcatctc caggcttcag
    21301 accagccaac agctgattga attttggccg atcccgtttt gtacccgtaa atttttctga
    21361 aaaaatattc ttcttctcta cgccgttctc aagcaactgt tgaatttgtt cttttgtact
    21421 ttgagaagcg gttgagacac gtgcatatcc atatttcgtc atttggtcca cctactttta
    21481 caaatcatct atcgtatact cagaataccc ttcatagaaa tagctgacat cgattccttt
    21541 catatataac tcgcgatcgt caattttatc agtcagagca ttggaaatta gatagcgtat
    21601 ttccaaatcg tttatgggac ttcgctccat tgcagaaaga tagtctgctt tatcgattaa
    21661 gttccaatct acaacttttt gcaattcttc ctttaaaatg agatccagcc aaattctagt
    21721 acttcggcca tttccttctc gaaatgggtg agcgatattc atctccacat atttcttgat
    21781 aatctcttca aaagaagttt gtggcatctg atcaatatgc tgtaacgaat gttctaaata
    21841 cataactggt gcaaatcgaa aatttccttt tgcaatattg accgatcgga tttttccggc
    21901 aaaatcgtaa atatccgaaa atagaaattc atgaatttca gataaacctt taaatgtacc
    21961 aacttcgatt tcatttattt ttccacaatc gtacaattct ttcgcttttt gtttactgag
    22021 tttttcttca accttagcca actcaacttg attggttaat cccaatttat tctctaaaat
    22081 catgcgaaat ctccttaact ttatgacata agtttatgaa acactctcaa ccccattata
    22141 tcgcgatttt gtttatgtgt caaaaactat taagtttctg acccccgata gatttttcaa
    22201 gtgtctctat tttgcacagt ctagttggtt ctgttgcaaa gttttaaata aagaataaaa
    22261 tcccttacgg tatctatgat ttaagctggg attcccaata ataccttgat ttcagtacag
    22321 accgaaaacc cgaagagagt gccttctttt cgggttttct tatataatcc tcgaatggct
    22381 tccatgcctt taatcgtggt agaggcagtg cgtaaacttc gatagaattt attgcgtctc
    22441 tttactggac gatggtcttg ttcaatcaaa ttattcaggt atttaatggt acgatgttct
    22501 gtcccttgat aaaagccgta ttcttttagt ttcttaaagg cacttgtaat agagggggct
    22561 ttatctgtga ctacaacctt cggttcatca aactgcttca ctaaccgctt aagaaaagca
    22621 taggctgctt gtgtgtcccg tttttttacg taaccaaata tccaaggtta aaccatctgc
    22681 atcgatggct cgatacaaat aatgccattt tcctttaatt ttgatgtacg tttcatccat
    22741 tttccatgaa taaaaggatt ttttattttt ctttttccaa atttgataga gtagtttgcc
    22801 atattcttgc acccaacgat aaatcgtcgt atgagaaacg ttaatgccac gatcatataa
    22861 gatttcttga acttcacgat agctaaggtt ataacgaaga tagtagccca cggctacaat
    22921 aatcacatcc tgctgaaatt gctttccttt aaaatgattc atcgtcattc ctcctgctat
    22981 ctttttctat tattctacct tatttgatag tagatttaaa actttgcaac agaaccgtgt
    23041 gaagtatttc agtgaattat tagccagtag cgaaaggctc agtgtagatt tagaatcggt
    23101 tatccagtcc tacaattatg gtggtggttt cttagggtat gtggctaatc gtggaaataa
    23161 atataccttt gaactggctc aaagtttctc aaaagagtat tcaggtggcg aaaaagtgtc
    23221 ttaccccaat cccatagcca tacctatcaa tgggggctgg cgatacaact atggcaatat
    23281 gttttatgtg caactggtaa cgcagtatct tgtcacaaca gagtttgatg atgatacggt
    23341 acaagccatc atggacgaag cactgaaata tgagggctgg cgatacgttt acggtggagc
    23401 ttccccgact acttcttttg attgtagcgg actgacacaa tggacgtatg gaaaagctgg
    23461 aattaactta ccacgaaccg cacaacagca atatgatgtg acccagcata tcccactatc
    23521 ggaagcacaa gctggcgatt tggttttctt tcattctacc tataacgctg gctcttatat
    23581 tactcatgtt gggatatacc ttggcaataa ccgtatgttt catgcaggcg acccaatcgg
    23641 ttatgccgac ttaacaagcc cctactggca acagcattta gtgggagcag gacgaatcaa
    23701 acaatgagaa aggaagattt aatgatgaaa tttagaaaaa atcagaataa agaaaaacag
    23761 ataccaaagg aaaagaaacc tcgtgtctat aaggtcaatc ctcataaaaa ggttgtgatt
    23821 gccttgtggg tacttttagg gcttagtttc agctttgcga tattcaagca ctttacagct
    23881 atagatactc atactattca cgaaacaact atcatagaaa aggaatacgt tgatactcat
    23941 catgtagaaa attttgtaga gaactttgcg aaagtctact attcatggga gcaatccgat
    24001 aagtccattg ataatcgaat ggaaagtcta aaaggctatc tgacagatga acttcaagct
    24061 ctcaatgttg atacagtacg caaagatatt cctgtatcgt cttctgtaag aggatttcag
    24121 atatggacgg tagagccaac tggcgacaat gagtttaatg taacctacag tgtagaccag
    24181 ctcattacag agggagaaaa tacaaagacc gtccactctg cttatatagt gagtgtctat
    24241 gtagatggtt ctggaaatat ggtactggtt aagaatccga ccattaccaa catacctaag
    24301 aaatcaagtt ataaaccaaa agccattgaa agtgagggga cggttgattc cattacaacc
    24361 aatgaaatca atgagttttt aacgacgttc ttcaagctct atcctacagc gacagccagt
    24421 gaactttcct actatgtgaa tgacgggata ttaaaaccaa tcggaaaaga gtacatcttt
    24481 caagaactgg taaatcctat tcacaatcgt aaggataatc aagtcacggt atcgctgaca
    24541 gtggagtata tcgaccagca gaccaaagca acgcaggtat ctcaatttga tttggtactt
    24601 gaaaagaacg ggagtaattg gaagattgta aaataacaaa tattggtaca tgattacaga
    24661 tactttgtaa tcatgtactc tttttgataa aaaattggag attcctttac aaatatgctc
    24721 ttacgtgcta ttatttaagt gactatttaa aaggagttaa taaatatgcg gcaaggtatt
    24781 cttaaataaa ctgtcaattt gatagcagga acaaataatt agatgtcctt ttttaggagg
    24841 gcttagtttt ttgtacccag tttaagaata cctttatcat gtgattctaa agtatccaga
    24901 gaatatctgt atgctttgta tacctatggt tatgcataaa aatcccagtg ataaaagtat
    24961 ttatcactgg gatttttatg cccttttggg tttttgaatg gaggaaaatc acatgaaaat
    25021 tattaatatt ggagttttag ctcatgttga tgcaggaaaa actaccttaa cagaaagctt
    25081 attatataac agtggagcga ttacagaatt aggaagcgtg gacaaaggta caacgaggac
    25141 ggataatacg cttttagaac gtcagagagg aattacaatt cagacaggaa taacctcttt
    25201 tcagtgggaa aatacgaagg tgaacatcat agacacgcca ggacatatgg atttcttagc
    25261 agaagtatat cgttcattat cagttttaga tggggcaatt ctactgattt ctgcaaaaga
    25321 tggcgtacaa gcacaaactc gtatattatt tcatgcactt aggaaaatgg ggattcccac
    25381 aatctttttt atcaataaga ttgaccaaaa tggaattgat ttatcaacgg tttatcagga
    25441 tattaaagag aaactttcta tggaaattat aatcaaacag aaagtagagc tgcaccctaa
    25501 tatgtgtgtg atgagctgta cggaacctga gcaatgggat gtggtaatag aaggaaatga
    25561 tgacctttta gagaaatata tgtccggtaa atcattagaa gcattagaac tcgaacaaga
    25621 ggaaatcaga agatttcaga attgctcctt gtaccctgtt tatcatggaa gcgcaaaaag
    25681 caacataggg attgagcagc ttatagaagt gataacgaat aaattttatt catcaacata
    25741 cagaaagaag tctgaacttt gcggaaatgt cttcaaaatt gaatattcgg aagaaagaca
    25801 acgtcttgca tatgtacgcc tttatggcgg aatcctgcat ttgcgggatt cggttagaat
    25861 atcggaaaag gaaaaaataa aaattacaga aatgtatact tcaataaatg gtgaattatg
    25921 taaaattgat aaggcttatt ccggggaaat tgttattttg caaaatgagt ttttgaagct
    25981 aaatagtgtt cttggagata caaagctatt gccacagaga gagagaattg aaaatccgct
    26041 ccctctgctg caaacaactg ttgaaccgag caaacctcaa caaagggaaa tgttacttga
    26101 tgcactttta gaaatctccg acagtgaccc gcttctacaa tattatgtgg attctacgac
    26161 acatgaaatt atactttctt tcttagggaa agtacaaatg gaagtgatta gtgcactgtt
    26221 gcaagaaaag tatcatgtgg agatagaact aaaagagcct acagtcattt atatggagag
    26281 accgttaaaa aatgcagaat ataccattca catcgaagtg ccgccaaatc ctttctgggc
    26341 ttccattggt ttatctgtat caccgcttcc gttgggaagt ggaatgcagt atgagagctc
    26401 ggtttctctt ggatacttaa atcaatcatt tcaaaatgca gttatggaag ggatacgcta
    26461 tggttgcgaa caaggattat atggttggaa tgtgacggat tgtaaaatct gttttaagta
    26521 tggcttatac tatagccctg ttagtacccc agcagatttt cggatgcttg ctcctattgt
    26581 attggaacaa gtcttaaaaa aagctggaac agaattgtta gagccatatc ttagttttaa
    26641 aatttatgcg ccacaggaat atctttcacg agcatacaac gatgctccta aatattgtgc
    26701 gaacatcgta gacactcaat tgaaaaataa tgaggtcatt cttagtggag aaatccctgc
    26761 tcggtgtatt caagaatatc gtagtgattt aactttcttt acaaatggac gtagtgtttg
    26821 tttaacagag ttaaaagggt accatgttac taccggtgaa cctgtttgcc agccccgtcg
    26881 tccaaatagt cggatagata aagtacgata tatgttcaat aaaataactt agtgtatttt
    26941 atgttgttat ataaatatgg tttcttgtta aataagatga aatatttttt aataaagatt
    27001 tgaattaaag tgtaaaggag gaattaatta tgaagtgtaa ttaatgtaac agggttcaat
    27061 taaaagaggg aagcgtatca ttaaccctat aaactacgtc tgccctcatt attggaggtt
    27121 gaaatgtgaa tacatccttt tcacaatcga atttacgaca caaccaaatt ttaatttggc
    27181 tttgcatttt atcttttttt agcgtattaa atgaaatggt tttgaacgtc tcattacctg
    27241 atattgcaaa ttattttaat aaaacacctg cgagtacaaa ctgggtgaac acagccttta
    27301 tgttaacctt ttccattgga acagctgtat atggaaagct atctgatcaa ttaggcatca
    27361 aaaggttact cctatttgga attataataa attgtttcgg gtcgttaatt gggtttgttg
    27421 gccattcttt cttttcctta cttattatgg ctcgttttat tcaaggggct ggtgcagctg
    27481 catttccagc actcgtaatg gttatagttg cgcgctatat tccaaaggaa aataggggta
    27541 aagcatttgg tcttattgga tcgatagtag ccatgggaga aggagtcggt ccagcgattg
    27601 gtggaatgat agcccattat attcattggt actatcttct actcattcct atgataacaa
    27661 ttatcactgt tccgtttctt atgaaattat taaagaaaga agtaaggata aaaggtcatt
    27721 ttgatatcaa aggaattata ctaatgtctg taggcattgt attttttatg ttgtttacaa
    27781 catcatatag catttctttt cttatcgtta gcgtgctgtc attcctgata tttgtaaaac
    27841 atatcag
//
