LOCUS       NZ_CP081355            27068 bp    DNA     circular CON 29-SEP-2023
DEFINITION  Staphylococcus aureus strain SQL1 plasmid pla1MRSASQL1, complete
            sequence.
ACCESSION   NZ_CP081355
VERSION     NZ_CP081355.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN20550080
            Assembly: GCF_019738975.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 27068)
  AUTHORS   Medrano,E.G. and Haydel,S.E.
  TITLE     Complete genome sequence of the methicillin-resistant Staphylococcus
            aureus SQL1 strain used for testing the antimicrobial properties of
            clay phyllosilicate minerals
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 27068)
  AUTHORS   Medrano,E.G. and Haydel,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-AUG-2021) Insect Control and Cotton Disease Research,
            USDA-ARS, 2765 F&B Road, College Station, Texas 77845, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: FALCON-Unzip v. jan 2021
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 1823.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 09/29/2023 07:02:42
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,927
            CDSs (total)                      :: 2,845
            Genes (coding)                    :: 2,762
            CDSs (with protein)               :: 2,762
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 42 of 83
            Pseudo Genes (incomplete)         :: 43 of 83
            Pseudo Genes (internal stop)      :: 17 of 83
            Pseudo Genes (multiple problems)  :: 18 of 83
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP081355.1.
            Bacteria and source DNA available from Shelley Haydel; Arizona
            State University Biodesign Institute  Center for Bioelectronics and
            Biosensors Tempe, AZ 85287-7501.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..27068
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="SQL1"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pla1MRSASQL1"
                     /geo_loc_name="USA"
                     /lat_lon="33.42 N 111.93 W"
                     /collection_date="2021-01-01"
     gene            complement(join(27021..27068,1..627))
                     /locus_tag="K1X69_RS14425"
                     /old_locus_tag="K1X69_14420"
     CDS             complement(join(27021..27068,1..627))
                     /locus_tag="K1X69_RS14425"
                     /old_locus_tag="K1X69_14420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            1101..2567
                     /gene="msr(A)"
                     /locus_tag="K1X69_RS14430"
                     /old_locus_tag="K1X69_14425"
     ARG             1102..2564
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            2666..3565
                     /locus_tag="K1X69_RS14435"
                     /old_locus_tag="K1X69_14430"
     CDS             2666..3565
                     /locus_tag="K1X69_RS14435"
                     /old_locus_tag="K1X69_14430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000196697.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            4051..4659
                     /locus_tag="K1X69_RS14440"
                     /old_locus_tag="K1X69_14435"
     CDS             4051..4659
                     /locus_tag="K1X69_RS14440"
                     /old_locus_tag="K1X69_14435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583528.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            4905..5243
                     /locus_tag="K1X69_RS14445"
                     /old_locus_tag="K1X69_14440"
     CDS             4905..5243
                     /locus_tag="K1X69_RS14445"
                     /old_locus_tag="K1X69_14440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001049146.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            5248..5433
                     /locus_tag="K1X69_RS14450"
                     /old_locus_tag="K1X69_14445"
     CDS             5248..5433
                     /locus_tag="K1X69_RS14450"
                     /old_locus_tag="K1X69_14445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000797248.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(5660..6403)
                     /locus_tag="K1X69_RS14455"
                     /old_locus_tag="K1X69_14450"
     CDS             complement(5660..6403)
                     /locus_tag="K1X69_RS14455"
                     /old_locus_tag="K1X69_14450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            6829..7812
                     /locus_tag="K1X69_RS14460"
                     /old_locus_tag="K1X69_14455"
     CDS             6829..7812
                     /locus_tag="K1X69_RS14460"
                     /old_locus_tag="K1X69_14455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001181107.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            <7832..8121
                     /locus_tag="K1X69_RS14465"
                     /old_locus_tag="K1X69_14460"
                     /pseudo=""
     CDS             <7832..8121
                     /locus_tag="K1X69_RS14465"
                     /old_locus_tag="K1X69_14460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            8668..8817
                     /locus_tag="K1X69_RS14470"
                     /old_locus_tag="K1X69_14465"
     CDS             8668..8817
                     /locus_tag="K1X69_RS14470"
                     /old_locus_tag="K1X69_14465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000695366.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(8985..9677)
                     /locus_tag="K1X69_RS14475"
                     /old_locus_tag="K1X69_14470"
     CDS             complement(8985..9677)
                     /locus_tag="K1X69_RS14475"
                     /old_locus_tag="K1X69_14470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            9787..9981
                     /locus_tag="K1X69_RS14480"
                     /old_locus_tag="K1X69_14475"
     CDS             9787..9981
                     /locus_tag="K1X69_RS14480"
                     /old_locus_tag="K1X69_14475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            11097..11714
                     /gene="cadD"
                     /locus_tag="K1X69_RS14485"
                     /old_locus_tag="K1X69_14480"
     ARG             11098..11711
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            11733..12080
                     /locus_tag="K1X69_RS14490"
                     /old_locus_tag="K1X69_14485"
     CDS             11733..12080
                     /locus_tag="K1X69_RS14490"
                     /old_locus_tag="K1X69_14485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            12237..12329
                     /locus_tag="K1X69_RS14495"
                     /old_locus_tag="K1X69_14490"
     CDS             12237..12329
                     /locus_tag="K1X69_RS14495"
                     /old_locus_tag="K1X69_14490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(12501..13472)
                     /locus_tag="K1X69_RS14500"
                     /old_locus_tag="K1X69_14495"
     CDS             complement(12501..13472)
                     /locus_tag="K1X69_RS14500"
                     /old_locus_tag="K1X69_14495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_000481279.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            13596..14015
                     /locus_tag="K1X69_RS14505"
                     /old_locus_tag="K1X69_14500"
     CDS             13596..14015
                     /locus_tag="K1X69_RS14505"
                     /old_locus_tag="K1X69_14500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            complement(14541..15386)
                     /gene="blaZ"
                     /locus_tag="K1X69_RS14510"
                     /old_locus_tag="K1X69_14505"
     ARG             complement(14545..15386)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            15493..17250
                     /gene="blaR1"
                     /locus_tag="K1X69_RS14515"
                     /old_locus_tag="K1X69_14510"
     ARG             15494..17247
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            17240..17620
                     /gene="blaI"
                     /locus_tag="K1X69_RS14520"
                     /old_locus_tag="K1X69_14515"
     ARG             17241..17617
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            17884..18462
                     /locus_tag="K1X69_RS14525"
                     /old_locus_tag="K1X69_14520"
     CDS             17884..18462
                     /locus_tag="K1X69_RS14525"
                     /old_locus_tag="K1X69_14520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690637.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(18685..18870)
                     /locus_tag="K1X69_RS14530"
                     /old_locus_tag="K1X69_14525"
     CDS             complement(18685..18870)
                     /locus_tag="K1X69_RS14530"
                     /old_locus_tag="K1X69_14525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001037130.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            19132..19806
                     /locus_tag="K1X69_RS14535"
                     /old_locus_tag="K1X69_14530"
     CDS             19132..19806
                     /locus_tag="K1X69_RS14535"
                     /old_locus_tag="K1X69_14530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105991.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(19975..20546)
                     /locus_tag="K1X69_RS14540"
                     /old_locus_tag="K1X69_14535"
                     /pseudo=""
     CDS             complement(19975..20546)
                     /locus_tag="K1X69_RS14540"
                     /old_locus_tag="K1X69_14535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /name="HTH domain-containing protein"
     gene            complement(20822..21616)
                     /gene="aph(3')-IIIa"
                     /locus_tag="K1X69_RS14545"
                     /old_locus_tag="K1X69_14540"
     ARG             complement(20826..21616)
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(21709..22239)
                     /gene="sat4"
                     /locus_tag="K1X69_RS14550"
                     /old_locus_tag="K1X69_14545"
     ARG             complement(21713..22239)
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="97.78"
                     /coverage="100.0"
     gene            complement(22236..>22871)
                     /locus_tag="K1X69_RS14555"
                     /old_locus_tag="K1X69_14550"
                     /pseudo=""
     CDS             complement(22236..>22871)
                     /locus_tag="K1X69_RS14555"
                     /old_locus_tag="K1X69_14550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251744.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="aminoglycoside 6-adenylyltransferase"
     gene            complement(23012..23686)
                     /locus_tag="K1X69_RS14560"
                     /old_locus_tag="K1X69_14555"
     CDS             complement(23012..23686)
                     /locus_tag="K1X69_RS14560"
                     /old_locus_tag="K1X69_14555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105956.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(<23743..23919)
                     /locus_tag="K1X69_RS14565"
                     /old_locus_tag="K1X69_14560"
                     /pseudo=""
     CDS             complement(<23743..23919)
                     /locus_tag="K1X69_RS14565"
                     /old_locus_tag="K1X69_14560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499250.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016311 - dephosphorylation [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /name="undecaprenyl-diphosphate phosphatase"
     gene            complement(23933..24670)
                     /locus_tag="K1X69_RS14570"
                     /old_locus_tag="K1X69_14565"
     CDS             complement(23933..24670)
                     /locus_tag="K1X69_RS14570"
                     /old_locus_tag="K1X69_14565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="WP_000369394.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            complement(24663..25592)
                     /locus_tag="K1X69_RS14575"
                     /old_locus_tag="K1X69_14570"
     CDS             complement(24663..25592)
                     /locus_tag="K1X69_RS14575"
                     /old_locus_tag="K1X69_14570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000793446.1"
                     /translation="MKNLNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAG
                     KTTTIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTIN
                     AKILGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPT
                     NGLDPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYED
                     LKKKNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLN
                     NIDVFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     gene            complement(25708..26589)
                     /locus_tag="K1X69_RS14580"
                     /old_locus_tag="K1X69_14575"
                     /pseudo=""
     CDS             complement(25708..26589)
                     /locus_tag="K1X69_RS14580"
                     /old_locus_tag="K1X69_14575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581923.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0000155 - phosphorelay sensor kinase activity [Evidence
                     IEA]; GO:0004673 - protein histidine kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="sensor histidine kinase"
     gene            complement(26586..>26963)
                     /locus_tag="K1X69_RS14585"
                     /old_locus_tag="K1X69_14580"
                     /pseudo=""
     CDS             complement(26586..>26963)
                     /locus_tag="K1X69_RS14585"
                     /old_locus_tag="K1X69_14580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834602.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /name="response regulator transcription factor"
     ARG             2667..3562
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             1102..2567
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             2667..3565
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             complement(21710..22227)
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="97.16"
                     /coverage="95.56"
     ARG             complement(22534..22835)
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     ARG             complement(14542..15386)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     Typing          8178..8325
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(5661..6403)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          6830..7812
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          7944..8113
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.605"
                     /coverage="91.0"
                     /evalue="1.04e-65"
ORIGIN
        1 gatctgaaga gacctacggt tctttttata tagagcgtaa atacattcaa taccttttaa
       61 agtattcttt gccgtattga tactttgata tcttgtcttt cttactttaa tatgacggtg
      121 atcttgctca atgaggttat tcagatattt cgatgtacaa tgacagtcag gtttaagttt
      181 aaaagcttta attattttag ccattgctgc cttcgttgaa ggtgcctgat ctgtaactac
      241 cttttgaggc ttaccaaatt gtttaatgag acgtttgata aacgcatatg ctgaatgatt
      301 atctcgttgc ttacgcaacc aaatatctaa tgtatgtccc tctgtatcaa tggcacgata
      361 taaatagctc cattttcctt ttattttgat atacgtctca tcaatacgcc atttgtaata
      421 agctttttta tgctttttct tccaaatttg atataaaatt ggggcatatt cttgaaccca
      481 acggtagatc gttgaatgat gaacgtttac accacgttct cttaatattt cagatatatc
      541 acgatagctc aatgcatatc ttagatagta gccaacggct acagtgataa catccttgtt
      601 aaattgttta tatctgaaat agttcataca gaagactcct ttttgttaaa attatattat
      661 aaattcaact ttgcaacaga accgtatttt atgagtacac tctaaattaa ggagatgtat
      721 aatcaatcta aaattgtatt tttatacttt tgttatataa tctttctact tagagatata
      781 ttgtaaaaaa accaacaaaa tgttatatta acattactat tttatcgatg aaggaggatt
      841 aaaatgacag cttctatgag actcaaataa acctttttga atacaaaact aaattaattc
      901 aaaaaggctt gtccgcaata cacactcata ggatgactta tgtcattttt tatccttcga
      961 taggaataat aaacgctttc aaatactaaa acatcataat aaatttttaa gtgtttgaaa
     1021 gtgtaatgtg aatgagacgg gagtagcctg tctcattttt ttgcgtacac gtcctttaaa
     1081 tatacaagga gtgtataaat atggaacaat atacaattaa atttaaccaa atcaatcata
     1141 aattgacaga tttacgatca cttaacatcg gtcatcttta cgcttaccaa tttgaaaaaa
     1201 tagcacttat tgggggtaat ggtactggca aaaccacatt actaaatatg attgctcaaa
     1261 aaacaaaacc agaatctgga acagttgaaa cggttggcga aattcaatat tttgaacagc
     1321 ttaacatgga tgtggaaaat gattttaaca cgttagacgg tagtttaatg agtgaactcc
     1381 atatacctat gcatacaacc gacagtatga gtggtggtga aaaagcaaaa tataaattag
     1441 ctaatgtcat atcaaattat agtccgatat tacttttaga tgaacctaca aatcacttgg
     1501 ataaaattgg taaagattat ctgaaaaata ttttaaaata ttactatggt actttaatta
     1561 tagtaagtca tgatagagca cttatagacc aaattgctga cacaatttgg gatatacaag
     1621 aagatggcac aataagagtg tttaaaggta attacacaca gtatcaaaat caatatgaac
     1681 aagaacagtt agaacaacaa cgtcaatatg aacagtatat aagtgaaaaa caaagattgt
     1741 cccaagccag taaagctaaa cgaaatcaag cgcaacaaat ggcacaagca tcatcaaaac
     1801 aaaaaaacaa aagtatagca ccagatcgtt taagtgcatc aaaacaaaaa ggcacggttg
     1861 agaaggctgc tcaaaaacaa gctaagcata ttgaaaaaag aatggaacat ttggaagaag
     1921 ttgaaaaacc acaaagttat catgaattca atttcccaca aaataaaatt tatgatatcc
     1981 ataataatta tccaatcatt gcacaaaatc taacattggt taaaggaagt caaaaactgc
     2041 taacacaagt acgattccaa ataccatatg gcaaaaatat agcgctcgta ggtgcaaatg
     2101 gtgtaggtaa gacaacttta cttgaagcta tttaccacca aatagaggga attgattgtt
     2161 ctcctaaagt gcaaatggca tactatcgtc aacttgctta tgaagacatg cgtgacgttt
     2221 cattattgca atatttaatg gatgaaacgg attcatcaga atcattcagt agagctattt
     2281 taaataactt gggtttaaat gaagcacttg atcgttcttg taatgttttg agtggtgggg
     2341 aaagaacgaa attatcgtta gcagtattat tttcaacgaa agcgaatatg ttaattttgg
     2401 atgaaccaac taatttttta gatattaaaa cattagaagc attagaaatg tttatgaata
     2461 aatatcctgg aatcattttg tttacatcac atgatacaag gtttgttaaa catgtatcag
     2521 ataaaaaatg ggaattaaca ggacaatctc ttcatgatat aacttaaaaa ctatacacta
     2581 atttatattg aatattaggt tcatttatat caatataaaa aatacgttca caagaaaaat
     2641 ataatagaaa taaggatcca ataaaatgac tcgacataat gaaattatta aatgtgcaga
     2701 aaaatatcaa ttacacatcc aacctcaaac aatctcattg aatgaatcgg gacttgattt
     2761 tcaagttgca tttggaaaag ataaacatgg agtagaatgg gttttgagac taccaagaag
     2821 acctgacgtt tataaacgaa caaaacccga aaaacaaacg gtagacttct tacagaagaa
     2881 tgtttcattt gaaataccga agtggaaagt acatgcaaaa gaccttattg cttacccaaa
     2941 acttacaggt aaacccgcag ccacaataga tccagaaata caaaattatg tatgggaaat
     3001 tgaacacaaa ccattaccag aaaactttat taacacatta gctgaaacac tcgtagattt
     3061 acacaacata ccagaagaaa acattaacgt tcagcatata aatatcaaaa ccatacaaga
     3121 aataaaaaat gactttcaaa gaagaatgaa taaagttaaa gaaacttatg gcgtatcaga
     3181 tgaattatgg aacagatgga aacaatggtt agaaaacgac gaactatggc ctcgacatgc
     3241 gaccatgata catggggact tacatccagg acatataatg gtagataacc aagcaaacgt
     3301 cacaggtctc atagactgga ctgaagcaac ccactccgac ccatcaatgg actttatagg
     3361 acaccatcgt gtattcgacg acgaaggatt agagcaactt ataacagcat acggtaaagc
     3421 tggaggtgaa atatggccac gaatgaaaga gcatataata gaactcaatg cagtattccc
     3481 aatgtttatc gctgagtttg ctatggaatc aggagaatcg gcgtatgaaa cgatggcatt
     3541 gaaagagtta ggtatgaaag agtagaactt atattaaaag aggcccattt taaagacgaa
     3601 ggcaatcctg atgaaatttt aaaactgcgt ttaattagtg atggtctttg gttttctata
     3661 atgtattaaa tatctggaca tggaacaaat gcaacaaatg gaaagaatcg ttttcgaaat
     3721 ttctaactcc ttaaatcagg aggataaata aacggtcatt ttcattgaaa gcacttatat
     3781 aaatttcatc aattttaata cctaccgtaa atacatttca taagtattaa acagatgatt
     3841 aaaattttta gttaatttaa atatttatga tagagatgac cttcaaatga acggttctgt
     3901 tacaaagaaa aaatctatat ttatttttag taagttttaa ttatagatat gtacactttg
     3961 agtacaccct aaccatacaa aaagaattgt tgaaattata acaattaaaa cgtatgatta
     4021 gggtgtatat ttattatgga gtgaagatga atgattatag gttatgcgag agtatcatcg
     4081 atagatcaaa atttagaaag acaattggat aatttaaaga cgtttggtgt ggagaaaatc
     4141 tttacagaga aacagtcggg aaagtcagtg gaaaatagac ctgtatttca agaagcactc
     4201 aattttgtca gaatgggaga tcgattcgtt gtggaatcta ttgatcgttt aggacgtaac
     4261 tatgatgaaa ttattgaaac tgtgaattat ttaaaagaaa aagacgttca gttaatgatt
     4321 accagcttac ctatgatgaa tgaagtaatt ggcaatccat tactggataa gtttatgaaa
     4381 gatttaatca ttcaaatatt agcaatggtt tcagaacaag agagaaatga aagtaaacgt
     4441 cgacaagcgc aagggattca agttgcgaag gaaaaaggcg tatataaagg gcgcccttta
     4501 ctttattcac caaatgctaa agacccacag aaacgtgtta tttatcatcg cgtggtggaa
     4561 atgttagaag aaggcaaagc gattagtaag attgcgaaag aagttaatat cacaagacaa
     4621 acagtttata gaattaaaca tgataaggga ttatcttgat aaattgattg tcaatgcaaa
     4681 tgagcgtctc tcacagtgtc tcaaattcca taacatatta ttgaattgag attttaataa
     4741 ttatacaaga aaaaagagta cgagttcgca gctttctata tagtaattgt tttactaata
     4801 aggtgtttta aaatatatta taatgtaaaa agtatttgac atttgtatca aaaatattta
     4861 cactcataaa tgtcaaatac tttttacatt tatgaggtgt tataatgaat ttaattcctt
     4921 ttattattat tttaattttt tcttgtttat ggacggctat aactaacaaa tatttacctt
     4981 cagaaacatt agataaaaaa ggacaacaag atcgatacga tgaaagacaa cgtaaaatgt
     5041 ttattgaaat actggctaaa agttttattt ggattgtata ttgtatgtta tttacactag
     5101 tgcttaaatt tacaggtttg tcaccaagta ttgaaggatc ttggttttct caatatccag
     5161 aaattttctt tataattgta gcactatttc ttatgctgtt taattactat actacaaata
     5221 aaaaatatac atctaaaggt taaattaatg aaaaatagaa ttagagaata tagaaaacaa
     5281 aaaggaattt ctcaagaaac tttaagtaaa gaattaaaag tgtctaggca aactattaat
     5341 gcaatagaaa acaataaata tgatcctaca ttgacattag catttaagtt ggcaagattg
     5401 tttgatacaa ctgtggatga attattttct taaccattca tttatcacaa aaagagagtg
     5461 cgaattcgca ctctcttttt gtgtagtagt actattaaat tttgtctcaa taacgaacgt
     5521 ttataacgca atcatgatga aagtattaat acagttaatt atttgaaata ctttagttta
     5581 cataatcgat gattaccaga agttctcact atataaaaga cactaaaatt ttataacttt
     5641 tagtgcctaa tcaattattt tagctaccaa acaaacgact ccaaaacccc tttttaggtt
     5701 ccgtttcttc actcttttct tctatatcac tatcattgtc atttagatta gctggaacgt
     5761 cttctttttt tgcttcttca ccttgtgtac tttcgtcgct ttgacttcca gatatatcct
     5821 tatattgaat ctctgtttct ttagtttctt cctgatctct gttaatattt acaggattag
     5881 tagtatatgt tttttcttgt gcatcaacgt tttgtctagt gttagtagat gtatcaaagg
     5941 gataattaag gtgtttttct ttttctaatt gattttctaa tttttgaatc tttttattac
     6001 tctctaatgc cagaacttgc tgattttcaa gcaattttga tctttcttgc aactcttttc
     6061 tgtaaaattc aattgttgtt tcatgacgac tttcttgttt ttcaatttga ttatttaaag
     6121 tatcaatctg atttttaagg atttctacta tttgagcatc gcttttcgat tcaaaattaa
     6181 tattatccga cccttttttt tgtttgtctt cagtagtact ttcaaaacca tatttctttt
     6241 tattttcatt tactctttga atgatttttt ctatatcggt atcttcttta ataaacgaag
     6301 tgttttcctg ttttattgtc tctatattca atcgcttaat attattaaaa atcgtttgct
     6361 tactaacccc taattcttca ctcaactttt tcacactttt catatcatca accctttata
     6421 aaatgtttat aaacccttga taaaatatta taagcttata atgcttaata ataaagtgat
     6481 taataaataa aaataaacat ccatcaacct ttttatcaag ggtttatgaa aggtttatga
     6541 tatttatcaa gggtttataa acccttgata aagctatatt ttccctttta taagtttatt
     6601 taaagtgcta taataaactt aatataacaa aaaccccaac tactggtaat agtcggggtt
     6661 tggtaataaa acgtttagaa actgtttatt tatataattt tcgatacttg tattatataa
     6721 tgaataatat cttagtgcaa gcacctaaat cattaaataa atgtaaagct aaataaaaac
     6781 gttttattac ctcttaccaa actaaaatat ggaaagaggt tttttgtcat gcaaaatcaa
     6841 tattttacag tgcaagaaaa ttacaaagaa agattttatc aaatccctaa agtattcttt
     6901 accagtgaaa attataaaaa tctaactaat gatatgaaaa tagcctatgc tatcttacgt
     6961 gatcgcttaa atttatctat taaaaatagc tgggttgatg aagatggtaa catttacttt
     7021 gtttattcaa atgaaaagct aatggaaatc ttaaattgta aaaaagaaaa gttaacaaaa
     7081 ataaaaaaag ggttagaaaa cgatggtcta ctcattcaaa aacgacgtgg tttaaataaa
     7141 ccaaatattc tatatttaat gaaacctatt gtcacagaac gtgatattta caaaatagaa
     7201 aaagaagaaa acgatgttga accttacggc gagaaggaag ttcgaaaatc gaacgtccag
     7261 aagttcgaaa atcgaacgtc cagaagttcg aaaatcgaac gtccagaagt tcgaaaatcg
     7321 aacactaatg atactgactt taatgacatt gactttaatg atactgagaa taatgatatg
     7381 aatgacttga atgatataaa gtacaaaaat gaaattagta atcattcaaa tcattcaaat
     7441 caatttacac ataattttga tgataaagaa atgctattgc aagaattccc agaacaacta
     7501 actaattatt tattaaaata tgattataga gatttagaaa tcataaaggc tgttattctt
     7561 aaagcaaaaa aatcatttaa ttcaaggcat gaagatatgc attacatgtt agaggacatt
     7621 gaggatgaaa tattaacttc tttaaaaaga cttaaaaaag ctatacatga taggggagtt
     7681 aaaggccaaa aggaaacaat caagtcaatg caagcttatt taatgcaaac aattctaact
     7741 gaacttgaag aaacacatgc cctttatatg cgccgtaaaa acatgaaaca atataatatc
     7801 tttaatcaat aattcaaatg attttataac actcgaagag acatcaaaat attccgttaa
     7861 atcatctgac tttttaactg atgacgacga aaaaaatcaa gaaattgtaa gtgatttaga
     7921 aaaaggtttg tatcgaaaac gtatgttaag ttatggtgga ttgcttaaac aaaagcataa
     7981 aattttaaac ttagacgatg ccgaagatgg taatttgatt aatacaagtg atgaagataa
     8041 aacgacagac gaagaaaaaa agcacattca attaccgcaa tttggaattt cgaaaagcaa
     8101 aattattatt taagacatta gtgataactg atgtcttttt ttattgtttt tctgtaaaaa
     8161 agtgctgtct tatttttgtg acaaatgctg tatgtagtgt cacaaaagtg tgacactaca
     8221 gctttgtatg atatcacttt aaaataactt aaaacccttg gaatgtctgg ccttgccaga
     8281 tctatcattt ttgaatgata gcaaatttcc cttatgctct tacggagatt ttagagttaa
     8341 attaaaattt ctaagttttt gataagaaaa gccctgcagg aatttagaaa aacatgggga
     8401 agttttaaag tattttatgc taatttttaa atttgcatgt aaatgggcag tatctaaaaa
     8461 attagtcact gattttgctg aaatttttgt ttgtgaaatt agcatatatt tatttggctc
     8521 atatttgcgt tttaagagac tgtatagatt tttaagtaca aaacctatat gatttgcctc
     8581 taagtcttca aaatgcctct taaaatccaa aataaaagtg tttaatattg taataaggat
     8641 tgctattttt ataaaaggag agatatcatg aagattaaaa ctttcgctac ttttactcat
     8701 cgtcaattag ataaacaagt taataggttt ttaaagaatg atattcatgt attagaaatt
     8761 caaacacaca gtaattggtt atatatttca gctattgttt tttatgagga taaataagga
     8821 acatcgtatt tatgccgaaa aaatttattg atgttgagaa gaacccttaa ctaaacttgc
     8881 agacgaatgt cggcatagcg tgagctatta agccgaccat tcgacaagtt ttgggattgt
     8941 taagggttcc gaggctcaac gtcaataaaa caattggaat aaaatcaacc tacagagcat
     9001 ccagctgcaa atgcagttcc gcaaactgct tcacatacac cgccggctat tggatttacg
     9061 attgcccata ctccacagta gtgagcacat gcataaagtc cagccatact acaagcgaat
     9121 gctttgccgt tccatttgaa tcctgcatat gttaccggtc tgtttttatc aactttttca
     9181 gccttatatt caacgtaatt tttgttaata agtatttttc cctctttgtt ttcagtcata
     9241 cttctttttt cggcaatgaa ttttgtgatt tttttgttgt agttatcata tattgtttca
     9301 gaaactacaa tttcttttgt tttttcattt ttataagcgt tattagctat gtagccatat
     9361 gcatttttat catttgcttc tgtagctaga tattttaatt tagaattttt gtcttctagc
     9421 tttatttttt taaatccttc ttttttcatt tgcttttcga atttttgcat atcttcattt
     9481 ttattttgca attgttctag aaaacttatt tctttcttgg tcatttgtga tacttcgatg
     9541 tttttgcttt tcaatttttc tttttgattt tctagtaaag aacttttttg ttcttcattt
     9601 gcgtaagcat tagaaaaatt cgcgctaaat accagtagga acaaggaaat tattgaaaat
     9661 aattttataa ttttcatttg atacctccaa gataataaga tattttaatt gtataagtaa
     9721 gcgctttata aaatcaatat ttattttaat atatttataa acatattttt gaaaggagtc
     9781 tattttatga atgaaaattt agaaaaatat ataaaaagtt tgccactttt aggtttgtta
     9841 attagtattt tgttaattgt tttattcttt tttattttag atgttgatga agatttattc
     9901 gtggtttttt tatactgttt attgcctttg atagttaatt tgtctattta tggtttttat
     9961 gtttttgtta aaagaaagta agattatgaa taattttgtt tttaatttgt atgctttgag
    10021 ggggttggaa aacggtaggt gtatagatta gatttcttgt ttttttgaaa cgagtgtgaa
    10081 cgagtttctt cttgtcttga tttttgataa aaacgcccta caggaattta gaaaaacgtg
    10141 gggaagtttt aaagaatttt atgctaattt ttaatttgca tgtaaatggg cagtgtctaa
    10201 aaatagttat tgtttttgct caaatttttg tttttgaaaa tagcatatat ttatttggct
    10261 catatttgcg ttttaaaagc atatataagt tttagatata aaactatatg aatcacccct
    10321 aaatctttaa aatgccctct taaaattcaa aataagggca taaaaaataa aagctacccc
    10381 agataaagtg aggtagcttt ttctttcata cggtctattt atttttcttt cgacgccgta
    10441 tcgtcgatgt aattcaaaaa agttatgggc tataaatcta catcactttt tcaagaatgt
    10501 agtagcaata ttcaacgcaa attaattttt ataactgctc ggaatatctc aagccgtttc
    10561 tttaattttg aaataaaaaa atcgacgaag gtcgattacg tttttgcaca tgtcgattta
    10621 tccgacgtat aagtgcgccc ttacgggatt taactagatt ataacgacga attttagacc
    10681 tgtaaagcaa taacaattag gtctaccagg tagataaagt gtacaaagta gaaccgaaaa
    10741 agttatttat tttgaagatt tttcgtagat ataatttgct aataaacttc ctaaaactga
    10801 ataaagaaaa atagttaaac tcatgtaatc actccataat tctgaagtgt ctccatgtct
    10861 acgcatagac acgcatttat gccgaaaaaa tttattgatg ttgagaagaa cccttaacta
    10921 aacttgcaga cgaatgtcgg catagcgtga gctattaagc cgaccattcg acaagttttg
    10981 ggattgttaa gggttccgag gctcaacgtc aataaagcaa ttggaataaa gcacctatga
    11041 ttatttaaaa atataagtta taatacattc aaaaatattt ttgaatgagg tgtattatga
    11101 ttcaaacggt tgttgctgct gctgttcttt atattgctac agcagttgat ttattagtaa
    11161 ttttattaat attttttgct agagcaaaga ctagaaaaga atatagagat atttatgttg
    11221 gtcaatattt agggtctatt attttaatat tagttagttt gtttttagct tttgtattaa
    11281 attatgttcc agaaaagtgg atattaggtt tattgggttt aataccaatt tatcttggaa
    11341 ttaaagtggc tatttatgat gattgtgaag gagaaaagag agctaaaaaa gaattgaatg
    11401 aaaaaggatt gtctaaatta gttggtacgg ttgcaattgt tacgatagca agttgtggcg
    11461 ccgataatat tggtttattt gttccgtatt ttgtgacatt aagtgttact aatttattac
    11521 ttactctgtt tgtcttttta attttaattt tcttcttggt gtttactgca caaaaattag
    11581 ctaatattcc aggaattgga gaaattgttg agaaatttag tcgttggatt atggctatta
    11641 tttatatagc tttaggttta tttattatta ttgaaaatga cactattcaa acaattttag
    11701 gatttatatt ttaatttagg gtgtgatttt atatgagtta tgaaaatact tgtgatgtga
    11761 tctgtgtaca tgaggataaa gttaacaatg ctttaagttt tttagaagat gataaatcta
    11821 agaaattact taacatttta gaaaaaattt gtgatgagaa gaaattgaaa atcatattat
    11881 ctttgattaa agaagatgag ttgtgtgttt gtgatatttc tttgatattg aaaatgagtg
    11941 ttgcttcaac ttcacatcat ttaaggcttt tatataaaaa tgaggtactt gatttttata
    12001 aagatggaaa gatggcatat tattttatta aagacgatga aataagagag tttttctcta
    12061 aaaatcatga gggtttttga aacgagtttc ttcttgtctt gatactataa aaaacaaagt
    12121 tatataacat aagacgactt atcggaagta gatatgcttg tatattcaca gatggtataa
    12181 taatagagtc gcctatctct caggcgtcaa ttgacgaaga gaggaggtgc attactttgc
    12241 taatcatttt cgttcacatc atagcaccag tcatcagtgg ctgtgctgtt gcgtattata
    12301 cttattggct tagtaaacgc aacaaataat taataggcga ctttataagc cagcatcgaa
    12361 aaaatcccca cactactgca atagtgtggg gattggtgca ttaattgtta atcattttcg
    12421 ttatataaat tataacactg gttagtagag aaatgcaaaa tgattgaatt aatagtaaat
    12481 gtattaatga atactcacac ttatactttt aaaatagttc ttcctaaatg ttgtcctttt
    12541 aaaagctgat ctatcgtttt atagaattct tcaaatccaa tttcattgta tagaagtgaa
    12601 tttcctatat tccattcatt tgctaactta ctccatatat cttcacggat attatgatca
    12661 acatatacag aatcaatgcc aattaattta atacctctaa gaataaacgg taatatatta
    12721 gcgttaagtg aatttcctgc tacatttcca catacagtag caacaccttg ataatttaga
    12781 cgttttaaac cgtataatgt tacattactc cccactgtat ctaagaaata atcaaaaata
    12841 ccttttttaa gcggtttatt atcatcttca attattatta cttgttttgc acctaatttt
    12901 tttgcgattt ctatttgctt ttcttttctt acgatagcag tgatattttc atatccaatt
    12961 ttatgtaaaa tttgtatagc aacactgccc acaccacctg tagccccaga cactaaaatt
    13021 tcaggttgtg atttgatatt cattccatat ttttctagtt caaaaattga taatgctgcc
    13081 gtaaaaccgg ctgtgccata taccatagac tctttaatag acatttcttg gggaatagga
    13141 acaatccact ctccaggcac ttgtgcatat tctgaaaatc cacctgtatg tgtcacgcca
    13201 acatcataac cagtaactaa tacattatcg ccttctttaa acttatcatt cgaacttgat
    13261 tcaacaatac ctgcaaaatc tataccagga atcataggat aatctctaat tacaccgcct
    13321 ttatattgta aagctagcat atccttataa tttattgaag agtataccac ttttactaat
    13381 acatcaccct tcgataaatg agattcatca actttttcta ctttataact aacatttgat
    13441 gcactttttc tcactactac cgcattgaac atttattagc cttctttcac aattgttttg
    13501 tagaagtatg tttttgttgc aaaactattt tcctacaaaa cttatcatga tatgataagc
    13561 gagtcaatac taatgattta agagaggttt tagttgtgga attagataat tgtataaatt
    13621 atttgttgag tacttctcag aatagagttt ttaaacattt taaaagttta ttaagtccct
    13681 ataatattac tccagcagaa tatggtgttt tgaattgctt gattaatagt aatttgaata
    13741 cacctaaagc gattggtaat actttaaatt tagaaccttc aacaatatct ggaatattag
    13801 ataagatgtc caaaaaggat ctaataacac gtcaaactga taatgaaaat agaagaactg
    13861 tgctaataaa cagtacaaat aaagcaaaag acttatggcc aacattagaa aagaaagcct
    13921 atcaacttaa taatcattac ttcgctaatt taactaatga agaaactgta gtgtttaaaa
    13981 agatattact aaagataaat aaaactacgt tttaattttt acgttataaa aaagttgaag
    14041 tgcgaattat aatcgagtaa atataaatga tagcttagct taattatata ttaaagccaa
    14101 ctatactttt attcccgaaa aacctactat ccaaatttct aagatacttt agcctctata
    14161 ataaacatat tgtaatataa tttatgtatt atttaggttt accctaatcg aacaataaaa
    14221 aatacttgta aaatgctatt gtcactttgc ttgatatatg agaattattt aaccttataa
    14281 atgagaaaaa agcaacgcac tttaaataag atacgttgct ttttcgattg atgaacacct
    14341 ataattaaac tattcatcta ttatttatga ttttttgtat atacaatatt tctagtttgt
    14401 taaagagaat taagaaaata aatctcgaaa ataataaagg gaaaatcagt ttttgatatc
    14461 aaaattatac atgtcaacga taatacaaaa tataatacaa actataagat gttatcagta
    14521 tttattatgc atttagaata ttaaaattcc ttcattacac tcttggcggt ttcacttatc
    14581 aacttatcat ttggcttatc acttttattg tctttattcg taaaaatgac taaaacaata
    14641 ggttcagatt ggcccttagg ataaacaaaa gcaacatcat ttctagaagc atatgttatt
    14701 gcttgaccac ttttatcagc aaccttatag tcttttggaa caccatcttt aattaaagtg
    14761 tctccgtttt tattattaaa cattaaatca agtaagaaat ttttattttt tttgcttaat
    14821 tttccatttg cgataagttt atttaaagtc ttgccgaaag cagcaggcgt tgaagtatct
    14881 tttttgctct ttggtgaata gtaatttaat tctatctcat atctaactgg atttgttact
    14941 ttatctccta gttcttttag acgttgttta acttttttga ttccaccgat ttcttttata
    15001 attttattgt ttgctgtatt atcactatat gtcattgaag cctcaataag ttcttttaaa
    15061 gtgatatctt ttcctacata tttttctaaa ataggagaat aagcaactat atcatctttg
    15121 ttaatatgta cttttttatt taacttatta taaggtactt gttctaacaa aatagcacta
    15181 tttatcgctt ttgaagtcga agcataggca aatctcttat ctgaattaaa ttttacttcc
    15241 ttaccacttt tagtatttaa agcataaaca ccaatatgag cattatattt tttttctaaa
    15301 tcatttaact ctttggcatg tgaactgttt gaattacatg cacttaaaac taaagcaatt
    15361 acaattaaaa atattaactt tttcaaaata aaccctccga tattacagtt gtaattttta
    15421 taaatcaata atattacaat tgtaatattg atgtcaattg tttattataa atatttgaaa
    15481 gaaggtgtca aaatggctaa attactaata atgagcgtag taagcttttg ttttatattt
    15541 ctattgttag tattttttag gtacatatta aaacgctatt ttaattatag tttaaattat
    15601 aaagtttggt atctaactat gcttgctgga ttaattcctt ttatcccaat taaattctct
    15661 tttataaaat ttaataatgt gaataatcaa gcgcccacag ttgaaagtaa gtcacacgat
    15721 ttgaaccata acataaatac caccaaacct attcaagagt tcacaacaga tatccataag
    15781 tttaattggg attcaattga taatatctgc acagttattt ggatagtttt agttattatt
    15841 ttaagtttta aatttttgaa agccttatta tatcttaaat atttaaagaa acagtcactt
    15901 tatctaaacg aaaatgaaaa aaataaaata gatacgatac ttttcaacca tcaatataaa
    15961 aaaaatattg tgattcgaaa agcagaggct attcaatctc caataacttt ttggtatggg
    16021 aaatatatta ttttgattcc tagttcatat tttaaaagtg taattgataa aagactaaaa
    16081 tatataatac tgcatgaata tgctcatgct aaaaatagag atactttaca tttaattatc
    16141 tttaatatct tctctattat tatgagttac aatccattag tacatattgt aaaaagaaag
    16201 ataattcatg acaatgaagt agaagccgat agatttgtcc ttaataatat taacaaaaat
    16261 gaatttaaaa cttatgcgga atctattatg gactccgtat taaaaacccc attttccaac
    16321 aaaaatatat taagccattc atttaatggt aaaaaatcat tactcaaaag tagattaatt
    16381 aatataaaag aagccgatct gaaaaagcag tcaaaattaa ttctaatttt tatttgtatt
    16441 tttacttttt ttatcatgat aattcaaagc cagtttttaa tggggcaatc cttaactgat
    16501 tataattata aaaagccctt acaaagcgat taccaaattt tagatgaaag taaaaatttt
    16561 ggttcaaata gtggatcttt cgttatgtac agcatgaaga aagacaaata ctatatttat
    16621 aatgaaaaag aaagtagaaa aagatattct cctgattcaa cttacaaaat ttatttagca
    16681 ctgtttggac ttgaccgtca tattataagt gataaaaatt cacgtatgtc atggaatcat
    16741 aaacattatc ttttcgagtc ttggaataag gaacaagatt taaatacagc aatgcaaaat
    16801 tcagttaatt ggtacttcga acgtattagt aatcaaatac caaagaacta tactgcggct
    16861 caactcaagc aattaaatta tggtaatgaa aatttgggaa gttataaaag ctattggatg
    16921 gaagatagtt tgaaaatatc taatcttgaa caagtaatag tttttaaaaa tatgatggaa
    16981 caaaataacc attttagtaa aaaagcaaag aatcaattat cttcttcatt attgattaag
    17041 aaaaatgaaa agtatgaact gtatgggaaa acaggtacag gtatagtaaa cgggaagtat
    17101 aataatgggt ggtttgtagg ttacgtaatt acaaatcatg ataagtatta ttttgctaca
    17161 catttatcag atggaaaccc gtctgggaaa aatgctgaat taataagtga aaaaatatta
    17221 aaaggaatgg gtgttttaaa tgaccaataa gcaagttgaa atatctatgg ctgaatggga
    17281 tgttatgaat ataatatggg ataaaaaatc agtatcagct aatgaaattg tagttgaaat
    17341 tcaaaaatat aaagaagtta gtgataaaac gattagaaca ttaatcacaa gactatataa
    17401 aaaagagatt ataaaacgat acaaatcaga aaatatttat ttttactcat caaatattaa
    17461 agaagacgat attaaaatga aaactgctaa aacctttctt aataaactgt atggagggga
    17521 tatgaaaagt ttagtgctga attttgcgaa aaatgaagaa ttaaataaca aagaaattga
    17581 agaattgcga gacattttaa atgatattag taaaaagtaa ttagaggtat gtttcaaaca
    17641 taatacatat gtaaaccata cttgactctt attaaattag ttttgttaat gacatttaaa
    17701 atatattatt aaagatgaga gtgtccagaa aataaccatt ttctgtacac tcttgttttt
    17761 tgtctaaata agtaagtatt acatagaatt atgtgttcaa aaacccaaca aaaaatctat
    17821 gttcacaaaa gacctcgtaa tcaagttatg gtacactaaa ggtgtatata ggaggtctgt
    17881 attttgaaaa taggttatgc aagagtttca actggattac aaaatttgaa tttacaggag
    17941 gatcgattaa atacatatgg ttgtgaaaag atatttaatg accatatgag tggttcaaaa
    18001 agtaagcgac ctggtttaga taaagcaatt gaatttgcga ggtcaggaga tacgattgtt
    18061 gtttggagat tagatagact aggacggaac atggaggatt taatcacgtt agttaatgaa
    18121 cttaacgaac gaggtgtgag ttttcatagt ttagaagaaa atataacgat ggataaatca
    18181 agttctacag gacaattatt atttcattta ttcgcagcat ttgcagagtt tgaacgtaat
    18241 ttaattttag agcgatcatc agccggtcga attgcagcac gtgctagagg ccgatatgga
    18301 ggtagacctg aaaaattaaa taaacaagat ttaaacttac ttaagacact ttatgataat
    18361 ggtacgccaa ttaaaacaat tgcagagcag tggcaagttt cacgtacaac tatttatcgt
    18421 tatctcaata aattagaggc aaaagagaat aaaaacaagt agagcaacta atctagctta
    18481 ctataatgaa tctactaaat aattttatat atcattaaca tacaaagact ttgattcaat
    18541 gtcactcgat gtaaaagaga cgttctgaca gcgtctaaaa tctcataata ttttcctgtt
    18601 atgagatttt aataataaca caagaaaaaa gcgtacaaat tcgtacgctt ttttaatata
    18661 atacctgttt cactaatgaa cgttttaagt atcttcatca ttaactgaaa ctacagtaat
    18721 aatactcgtc aacaatatta gtatagttaa aatagaaaga cttaggactg gcataaccga
    18781 actaaaatta tatttgaaat ataaaagtgc taatgaagag agaaatgtaa aaataataaa
    18841 taccaaagac catttttcta atttattcat tggcttcacc tctttgaact tttatataat
    18901 cataggagat atttttacta cgatttataa aaaataagaa gataatcatt attaaagaaa
    18961 cgattaatat aatgttgaat cctatagtat cacctaattc gtttacacct ttgcctaata
    19021 tcggagatac aaagctttgt attaataatg aaagagatgc ccatatagta aatgaggttc
    19081 tgttgcaaag ttgaatttat agtataattt taacaaaaag gagtcttctg tatgaactat
    19141 ttcagatata aacaatttaa caaggatgtt atcactgtag ctgttggcta ctatctaaga
    19201 tatgcattga gttatcgtga tatatctgaa atattaaggg aacgtggtgt aaacgttcat
    19261 cattcaacgg tctaccgttg ggttcaagaa tatgccccaa ttttatatca aatttggaag
    19321 aaaaagcata aaaaagctta ttacaaatgg cgtattgatg agacgtacat caaaataaaa
    19381 ggaaaatgga gctatttata tcgtgccatt gatgcagagg gacatacatt agatatttgg
    19441 ttgcgtaagc aacgagataa tcattcagca tatgcgttta tcaaacgtct cattaaacaa
    19501 tttggtaaac ctcaaaaggt aattacagat caggcacctt caacgaaggt agcaatggtt
    19561 aaagtaatta aagcttttaa acttaaacct gactgccatt gtacatcgaa atatctgaat
    19621 aacctcattg agcaagatca ccgtcatatt aaagtaagaa agacaaggta tcaaagtatc
    19681 aatacagcaa agaatacttt aaaaggtatt gagtgtattt acgctctata taaaaagaac
    19741 cgcaggtctc ttcagatcta cggattttcg ccatgccacg aaattagcat catgctagca
    19801 agttaagcga acactgacat gataaattag tggttagcta tattttttta ctttgcaaca
    19861 gaaccagcat ttgttttaat atttgttcca aagagccatc atggctttga cagagctctt
    19921 cttctatgca aatgctttta atccgatcca cacgaaaatt cctatattca tttcttagcc
    19981 tgcaaaaccg attaagtacc agttctgttc ataaaacccc agtgatatag gctctatcat
    20041 tctgctttcc ggttcttgcc ctcctgatgc aggatattga attgatatta cccttttatt
    20101 gcagattgca gtctgaattg ctgcaataac gttatccgcc aatgtatttt tctgtccaga
    20161 tgtgctgtac acgttaatac tgttctccaa ctcctgtgca tagttttttt caccatgctt
    20221 caaaatagat ttgattttat acatagctga atcaaaatcc tttataaatg attcatctcc
    20281 atggcaattt aaaaatttcc ctgctgtaat caatgcaccc acttccgccg ctgtaaacat
    20341 taccggcaga agtaggaagc cctctacaag aaaatatcct tttccggcct cagatccaat
    20401 tggtattccg gcttcttcaa gtgtccggat atctctgtaa actgtcctta agcttatatt
    20461 aaatcgctgt gcaatttctt tggcaggaat tatttttttg attgcagctg aataagaata
    20521 gaggttactc tgttaatcct gttcaaattt tattcctcct ctgtgacttc cataaaaagt
    20581 atatcctatg cgttcttaag ctagctgctg ttagtgcttc tcattgcacc ctggttataa
    20641 aagccatact cacaaacctc ttcaccaaaa ctctttacat ctctaatata gaactctatc
    20701 tagcgaactt ttagaaaaga tataaaacat cagagtatgg acagttgcgg atgtacttca
    20761 gaaaagatta gatgtctaaa aagcttgtag ttaaagcttt ttagacatct aaatctaggt
    20821 actaaaacaa ttcatccagt aaaatataat attttatttt ctcccaatca ggcttgatcc
    20881 ccagtaagtc aaaaaatagc tcgacatact gttcttcccc gatatcctcc ctgatcgacc
    20941 ggacgcagaa ggcaatgtca taccacttgt ccgccctgcc gcttctccca agatcaataa
    21001 agccacttac tttgccatct ttcacaaaga tgttgctgtc tcccaggtcg ccgtgggaaa
    21061 agacaagttc ctcttcgggc ttttccgtct ttaaaaaatc atacagctcg cgcggatctt
    21121 taaatggagt gtcttcttcc cagttttcgc aatccacatc ggccagatcg ttattcagta
    21181 agtaatccaa ttcggctaag cggctgtcta agctattcgt atagggacaa tccgatatgt
    21241 cgatggagtg aaagagcctg atgcactccg catacagctc gataatcttt tcagggcttt
    21301 gttcatcttc atactcttcc gagcaaagga cgccatcggc ctcactcatg agcagattgc
    21361 tccagccatc atgccgttca aagtgcagga cctttggaac aggcagcttt ccttccagcc
    21421 atagcatcat gtccttttcc cgttccacat cataggtggt ccctttatac cggctgtccg
    21481 tcatttttaa atataggttt tcattttctc ccaccagctt atatacctta gcaggagaca
    21541 ttccttccgt atcttttacg cagcggtatt tttcgatcag ttttttcaat tccggtgata
    21601 ttctcatttt agccatttat tatttccttc ctcttttcta cagtatttaa agatacccca
    21661 agaagctaat tataacaaga cgaactccaa ttcactgttc cttgcattct aaaaccttaa
    21721 ataccagaaa acagcttttt caaagttggc gtataacata gtatcgacgg agccgatttt
    21781 gaaaccacaa ttatgataga atttacaagc tataaggtta ttgtcctggg tttcaagcat
    21841 tagtccatgc aagtttttat gctttgccca ttctatagat atattgataa gcgcgctgcc
    21901 tatgccttgc cccctgaaat ccttacatac ggcgatatct tctatataag cgtaccggtt
    21961 ccaatttttt cgcagtttaa cttttccgac gcatttatcg tcttggtagt aaagatatat
    22021 tatcttatca gtattgtcaa tatattcaag gcaatctgcc tcctcatcct cttcatcctc
    22081 ttcgtcttgg tagcttttta aatatggcgc ttcatagagt aattctgtaa aggtccaatt
    22141 ctcgttttca tacctcggta taatcttacc tatcacctca aatggttcgc tgggtttatc
    22201 gatatctttc aggtgccctg ctttcatttc tgtaatcact gttcccgcct ctcttctata
    22261 tcagcggcat atgtgctatc caggcagccg gttttaccag tgtatttttt atacatgtcc
    22321 ctggtatatt ttgttatatt cctatcatac tccggatagg cataatgaag cctttccgcc
    22381 acctcaccgg ataccgccct gaacaattga tggcatagaa ataatgcttc ccatatgttt
    22441 tcataggaat ccatccggta ggtggacaaa agtttctccc acaaatcctc ggatatatac
    22501 ctttcaataa acttatagtt cttgcctaca cttcatttaa agcctgtttc gatgccgacc
    22561 ttccatgata tcattctcag cagctcatgg cgaacaatct gattaaaatg atcaatagca
    22621 aataaaattt ccttacggca caatccttta ataacataag gtgttacatt ccaaaattca
    22681 ttgcagcaat catcatactc ccttgcgctt ggctttctta catgataatc tatatcagtc
    22741 ggaactatgt cccttttaat tctacaatct ttatcaatta gaacctttat taatttatcg
    22801 ccctttaggt aattatctaa ctcttccaag ggcaataagg taagatcaat tttattgtaa
    22861 tcatcaaata gctataatag atttagaggt aaagaaatta aatacattga agagcagaaa
    22921 gattttacaa aagagtattt taataaaaat gatggttctg ttgcaaagta aaaaatatag
    22981 ctaatcacta atatatcatg tcagtgttcg tttaacttgc tagcatgatg ctaatttcgt
    23041 ggcatggcga aaatccgtag atctgaagag acctgcggtt ctttttatat agagcgtaaa
    23101 tacactcaat accttttaaa gtattctttg ctgtattgat actttgatac cttgtctttc
    23161 ttactttaat atgacggtga tcttgctcaa tgaggttatt cagatatttc gatgtacaat
    23221 ggcagtcagg tttaagttta aaagctttaa ttactttaac cattgctacc ttcgttgaag
    23281 gtgcctgatc tgtaattacc ttttgaggtt taccaaattg tttaatgaga cgtttgataa
    23341 acgcatatgc tgaatgatta tctcgttgct tacgcaacca aatatctaat gtatgtccct
    23401 ctgtatcaat ggcacgatat aaatagctcc attttccttt tattttgata tacgtctcat
    23461 caatacgcca tttgtaataa gcttttttat gctttttctt ccaaatttga tataaaattg
    23521 gggcatattc ttgaacccaa cggtagatcg ttgaatgatg aacgtttaca ccacgttctc
    23581 ttaatatttc agatatatca cgatagctca atgcatatct tagatagtag ccaacggcta
    23641 cagtgataac atccttgtta aattgtttat atctgaaata gttcatacag aagactcctt
    23701 tttgttaaaa ttatattata aattcaactt tgcaacagaa cctcctaact gtattaccac
    23761 cttaaaagta gttgcagacg cacttcctaa atcgtcagca gtgtttaacc acatatcatc
    23821 aacaataatc atatgacctg ttgatgatac tggagcaaat tctgtcaacc cttcaactac
    23881 acctaaaata aatgctttaa tctgctctat aaaacccatt tttctcctcc ttttaactta
    23941 tatcagtttt tttaaagtat gagaataata taattacact gaatatagat gtaacaatta
    24001 tgataattaa agataataga aatggataag tattaggtaa tgttcctcta gatatgtctc
    24061 caactgcagc ccaaggaaat aatcctctat gttcagaatt agcagtcatt aaatttatca
    24121 aagtaattat tatggttaaa acaattgtgg gaacataatt tttaaaatat atcgacaaaa
    24181 taattattgg tggagataat atccataata acactccgcc aataacaaat gtaaagaatg
    24241 aatcaattat taaactctgg cttaaccctt gaaaatgcaa tagcatacct agcattaaag
    24301 ttagcaacca tgcaataaca gatagtgttt gaatccacaa gaataataat attattttac
    24361 ttactaaaaa actttctcta gatataggta taattaataa gttttttaaa gtatcttcta
    24421 tatattctct tccaaacaaa taggctatta taaccccata tagaggaggt ccaataatta
    24481 gcatatgata taaactgact tcttcaaata actgtttaaa tacaatatta ggagtcggta
    24541 ctttcgtccg catactaata aaagaagcta caaccaccat aaaaggtgct acgcatgtac
    24601 ctaaaatact tattagaaac atatatgatc tttttaactt aataaattct gtacggagta
    24661 gattatccaa ttgtgccacc tcctactaag tcttcgaaat aagtttctag attatcttct
    24721 atcactctca tctggaaaac atcaatattg tttaatacta ataatctatt aatttcttgt
    24781 tgtctatcaa tatgtgaata aattttaaat tcgccatttt ctttaatttt atagtcataa
    24841 attccgaagt tagtttccaa caaacatgca actttttctt catctgatac tgatatactt
    24901 ataaattgtc tgttcttttt ttttaaatct tcatacataa tttcttctaa caaaactccg
    24961 ttatgaataa tacccacctt gtctactaac tgctctattt ctgacaatat atgacttgaa
    25021 attaaaatgg ttatatttct agattgagcc agatccttaa tcaactttct aatttctttt
    25081 atgccaatag gatctaatcc attcgtcggc tcatcaagta tcaataattc gggattgtgc
    25141 aataaagctc tcgcaatccc taaacgttgc ttcataccta aagaataatt tttaaacaat
    25201 tttacttttt cagaagctag tcctactatt tctaacactt cttcaattgc attttctttt
    25261 tgtataccta atattttagc atttatagtt aagttctctt tagctgtcaa attactataa
    25321 aaacctggcg tttcaaccat agcaccaata ttttttaaaa tttcagtttt attactttcg
    25381 aactcttttt caaatatttt aatattacct ttcgtaggtt taattaagcc taaaagcatt
    25441 cttatagtag ttgttttgcc tgcaccattt cttcctaaaa aaccataaat ttgtccactt
    25501 tcaacagtta tactcaaatt attaactgct atctgacttc catattgctt tgttaagtta
    25561 tttatttcaa ttatattatt caaatttttc acctctggca cctttcttag tttgttgtta
    25621 cctttatctt acgcgcgatt agaaaaggct gcctttatct attcttacaa aaacagccgc
    25681 taatcttaca aaaatgaaag attggagtta tttaaattga atggtgaata ttgaaccatc
    25741 gtttaatgta gatgtagcac ttactttatg gcctaagcgc tttgagattg tgctgacaat
    25801 atataaacca ataccgcttg atttctcact tattctaccg ttatagcccg agaaaccttt
    25861 atcaaagatt ttcggtaaat cactcgcatt aatgccgata ccgttatctc ggattgataa
    25921 tttctttgta ttttcgtcaa acgtaatcca cacatctttg ccacgtgcat attttaatgc
    25981 attgtttaat atttgctcaa tcataattga tgcccatttg gcatctgtta atataaccgc
    26041 ttcacttttc tcataatgca actttgtttg atgatgaata aactgtatcg cataacgttt
    26101 aatcagtggt cgaattaatt catctacact cacttccata aagaccatgt atgtcttttg
    26161 gttcatgagt ttcaaatagt tcagtgcaag attcgtgtaa ttatcaattt gtaagacttc
    26221 attacgcacg ttagaaatca cgtgttcatc aggatcttca agcagtaact ttgatgctgt
    26281 aatcggtgtc ttgatttgat gcacccacat taaaaaatat gactctaact cgctttggta
    26341 gttaataaag tcattacgaa gtttatggtt ttcgattctt aaatcttcgt tctgttcctg
    26401 tagtgtttat tcttttttaa agttcatgta atggataccc cagtaaatca ttgaaacaaa
    26461 caatacaata cctagaccaa tcatatatgc ttgcatcggc acattataca tgaataatat
    26521 aaagtagaat aaagcacaag taaggatgac aatataaatt tcacgttgga ttgatttcaa
    26581 gaaattcata cgtcacctac acgatatccg acatttttct tcgtttcgat aaaatctgta
    26641 agtcctagtt tttgtagctt tttgcgtaaa cgtgtaatgt tgacagcaag cgtattgtca
    26701 tcaatgaagt gttctgattc ccagcatttt tcgattaacg cattacgact gacgaatttg
    26761 cccttgttct ggaataagct atgcatgatt tgcaattcag tgtgtgtcag gtctatggtt
    26821 tcttcattaa atttaagctt tgctgcatca agtagtaact cgcaatcatc tactgttaaa
    26881 ttattaactt gagtggtgaa atcatacgtg cggcgtaata gtgcttgaat cttagtaatt
    26941 gtaacagtca tattaaatgg ctggttctgt tgcaaagtaa aaaatatagc taatcactaa
    27001 tatatcatgt cagtgttcgt ttaacttgct agcatgatgc taatttcgtg gcatggggaa
    27061 aatccgta
//
