LOCUS       NZ_CP081012            24185 bp    DNA     circular CON 22-SEP-2023
DEFINITION  Escherichia coli strain 25POL plasmid p25POL-B, complete sequence.
ACCESSION   NZ_CP081012
VERSION     NZ_CP081012.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN20701137
            Assembly: GCF_019645975.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24185)
  AUTHORS   Cao,G. and Zhong,C.
  TITLE     Complete genome of 25POL
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 24185)
  AUTHORS   Cao,G. and Zhong,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2021) College of Biomedical Sciences, Shandong
            First Medical University, 6699 Qingdao Road, Jinan 250117, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. 1.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 893.0x
            Sequencing Technology             :: Oxford Nanopore; BGISEQ
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 09/22/2023 05:38:20
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,068
            CDSs (total)                      :: 4,953
            Genes (coding)                    :: 4,722
            CDSs (with protein)               :: 4,722
            Genes (RNA)                       :: 115
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 6
            Pseudo Genes (total)              :: 231
            CDSs (without protein)            :: 231
            Pseudo Genes (ambiguous residues) :: 0 of 231
            Pseudo Genes (frameshifted)       :: 100 of 231
            Pseudo Genes (incomplete)         :: 138 of 231
            Pseudo Genes (internal stop)      :: 54 of 231
            Pseudo Genes (multiple problems)  :: 53 of 231
            Pseudo Genes (short protein)      :: 4 of 231
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP081012.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..24185
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="25POL"
                     /isolation_source="LAB"
                     /db_xref="taxon:562"
                     /plasmid="p25POL-B"
                     /geo_loc_name="China:Jinan"
                     /collection_date="2018-05"
     gene            458..553
                     /gene="dqlB"
                     /locus_tag="K3072_RS25630"
     CDS             458..553
                     /gene="dqlB"
                     /locus_tag="K3072_RS25630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinQ-like type I toxin DqlB"
                     /protein_id="WP_000609147.1"
                     /translation="MINLLIIVLRAVVAVANALIAILELIRQFID"
                     /name="dqlB"
     gene            620..799
                     /locus_tag="K3072_RS24950"
                     /old_locus_tag="K3072_24950"
     CDS             620..799
                     /locus_tag="K3072_RS24950"
                     /old_locus_tag="K3072_24950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000347020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000347020.1"
                     /translation="MDFMSILGRCLLLPFPVAMFVGCLFLGIDDRFTGMFMSFIVGCLS
                     WYITKPKPQKAEVA"
                     /name="hypothetical protein"
     gene            complement(1204..3105)
                     /locus_tag="K3072_RS24955"
                     /old_locus_tag="K3072_24955"
     CDS             complement(1204..3105)
                     /locus_tag="K3072_RS24955"
                     /old_locus_tag="K3072_24955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000407093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000407093.1"
                     /translation="MEIVSFKVSQYRSISGEISSDNFNGLTIVGQNNSGKTNLLKAMRV
                     FFEGKFNPDLYDYEKDKPHGVKQGQTSFAVRFTFSESELDDVSEDLSQDDDDDDDDSII
                     ELGVLGGQEEPSNSISFDDGSSKQQESKPTQSRGRKLSLRDRYLQLFNMIDDSRLSSPQ
                     NEVTVHLTISNKNNYFYTVFKGYKRKPEVTSSMYTSVERRFIEKILSSFECVYIPSSKS
                     IDDIYHNLLVPYVRSEVASAMKTSVQVIHDKLLEVSEKITNEMILSGIDDCSFMIKAPP
                     SLDELFGRFEVSIKDTIENVISSKGMGLQCLSLFSSFKSISERKLTLGKKTIWMVEEPE
                     SFLHPSLGRSCNHIFKSLMDVAYVLITTHSLSFVSDEPSKIIELYKDDAGVTKDKKHEK
                     RFNAVASIRENLGVRFSDFFNISSSAVFVEGITDKQYIESILKLTSEHDEFKNRWPFLR
                     SAKVDEFGGVSQLGGFLKGCYEFISKDVPVISVFDGDEAGVKERTRLQSYFGKKQIRFE
                     SNKDYISVRSGFAIEGLFPDDFISDAMETHPSWFIGGKSVDADDVIEPFKVQDNKKTNL
                     LNFFLERCRVQPICGWISRWEKVFNVIDSALRDKSESITNKKRTEDTSGNTSDHQAA"
                     /name="AAA family ATPase"
     gene            complement(3211..3720)
                     /locus_tag="K3072_RS24960"
                     /old_locus_tag="K3072_24960"
     CDS             complement(3211..3720)
                     /locus_tag="K3072_RS24960"
                     /old_locus_tag="K3072_24960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000190058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000190051.1"
                     /translation="MATEWVDVADNAVKIGLGALITIVGGWITLKLTHCHEIRKDAIAQ
                     RLRDIDKKTDRYIDFLSSSQTLMQKYLYESCNPGSEDYTNYMRLHNIVSLTSSPELRIY
                     AFDTQSKVSQFILLRKPNEPEVIDSCRNAARNAVSVLQGAVSAELLQDKAALQDKQHAW
                     WAFWRK"
                     /name="hypothetical protein"
     gene            complement(3812..4423)
                     /locus_tag="K3072_RS24965"
                     /old_locus_tag="K3072_24965"
     CDS             complement(3812..4423)
                     /locus_tag="K3072_RS24965"
                     /old_locus_tag="K3072_24965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000016733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000016733.1"
                     /translation="MSGRITTLCTAFGVVIAAVGLYLPYKNELNAALYQREFLTGKWST
                     DAEYIINSGDLGLDKPQSIMTIQLFVDKDGSIDGEFISEGLCDAMPLTWNITFNSDSPS
                     LINFIFARKFQIRQLVNGAMDKSPVVATLKLVDEDHKHNPIVFDVVNDSTGTLPKQITL
                     AKNLPKFEENYKYLQSYCANSTEKMYEKMMPEIRNLNKGL"
                     /name="hypothetical protein"
     gene            complement(4761..5243)
                     /locus_tag="K3072_RS24970"
                     /old_locus_tag="K3072_24970"
     CDS             complement(4761..5243)
                     /locus_tag="K3072_RS24970"
                     /old_locus_tag="K3072_24970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001546353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001546353.1"
                     /translation="MRDKTREAMRMFLGGRCYTAENLERDFLSELTRYSDERWEAPQRG
                     ARLAAAVKRYKTSEMLRFIFATIAYDPDPDLTPLAVKRLCNALFGRTGSQWLIVELFGD
                     KERQHRSNDSTLEAVEKMAARYRHAARQHWAATLDEIERVKRLYQEGIKASRIKES"
                     /name="hypothetical protein"
     gene            complement(6065..6709)
                     /locus_tag="K3072_RS24975"
                     /old_locus_tag="K3072_24975"
     CDS             complement(6065..6709)
                     /locus_tag="K3072_RS24975"
                     /old_locus_tag="K3072_24975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001503708.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000203201.1"
                     /translation="MTSNAPTNFVRAYLRASTAEQDASRALETIEAFARERGLIICSYY
                     IENESGSRLDRPELFRLLRDCQQNDILLIEDVDRLSRLSGEDWNTLKKMIRQKDIRVMA
                     VNVPTTWINSGMSEFDSRLFAAINDMLLDMLAAVARRDYEQRRERQKQGIEKARKDGKY
                     KGRKPNQARHDAIIRLIESGSSWTQVQKVLGCSRGTISSALKRKTGQKSSK"
                     /name="recombinase family protein"
     gene            7090..7752
                     /locus_tag="K3072_RS24980"
                     /old_locus_tag="K3072_24980"
     CDS             7090..7752
                     /locus_tag="K3072_RS24980"
                     /old_locus_tag="K3072_24980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division plane positioning ATPase MipZ"
                     /protein_id="WP_000516402.1"
                     /translation="MGKILLVVSDKGGVGKSTYVANTGSMLVNKGKSVIILKTDKNHDL
                     LSWNEKRTDNGLLTIPVHAAYGNVSNEIKRLSKLCEVLIVDCPGHDSQEFRSALTVSDI
                     VVTLVKPSSDFESETLTSVTEKIRTAQKANAALEPWVLFTRINSAKPRHRKAAIDLDKL
                     LRSDNIWIQPLKTRISELDVYESACNEGAGVHDVSRASSLSTAKAQIELVAQEIGIL"
                     /name="division plane positioning ATPase MipZ"
     gene            7850..8131
                     /locus_tag="K3072_RS24985"
                     /old_locus_tag="K3072_24985"
     CDS             7850..8131
                     /locus_tag="K3072_RS24985"
                     /old_locus_tag="K3072_24985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001185482.1"
                     /translation="MALKLNRPNIDESQQPATNAETARFISGATRAPVVGKPKLMNFRL
                     SAHFEDILEAEAIRTGQSKTTVLKAALAMYNSQDENIKNHWLLESAKF"
                     /name="hypothetical protein"
     gene            8156..9133
                     /locus_tag="K3072_RS24990"
                     /old_locus_tag="K3072_24990"
     CDS             8156..9133
                     /locus_tag="K3072_RS24990"
                     /old_locus_tag="K3072_24990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6685 family protein"
                     /protein_id="WP_001269914.1"
                     /translation="MRYLTELICQLYRLTDHHKLTAATFKNLADIKLVEPTADADTILQ
                     LENIFSEYSLRYIDRDLAEILSNIITTDKNHSLDFDFNKIQSLTASKSFGCGWNKVING
                     SWFKNLYSWGEGMYPAKNLKAENISDWEDNIWHIEHEGFNPRDPINVKYYSWLDRYVAL
                     NSGGSHHAAMVVYQSVRDKLEYKREAVIEQLSINSNTVEILGQNYYSFIFQIKHPSNKT
                     ENYTSEYEFTDALKDFGQNRHTTLKPVNYVSNIKLAFIPKDALKTNSETFRNWFYSAIS
                     YGKIISLPDYLKNPAHYHTYHYSHELDSITLGNPSRKYKLRGDS"
                     /name="DUF6685 family protein"
     gene            complement(9130..9555)
                     /gene="ddp1"
                     /locus_tag="K3072_RS24995"
                     /old_locus_tag="K3072_24995"
     CDS             complement(9130..9555)
                     /gene="ddp1"
                     /locus_tag="K3072_RS24995"
                     /old_locus_tag="K3072_24995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA distortion polypeptide 3"
                     /protein_id="WP_000202958.1"
                     /translation="MTSLTPFRNVCPVTYSRFLSENFMKYQVREFITDKYAKAVNILKD
                     NLKENYHVFYGVRLSEILFPASEYGTDAFFKEFELINSVILPLVIFDLTQRKPMMIISF
                     DKIPDASLLEGTNIVVLECTTLADLLTNDNIGFLYKS"
                     /name="ddp1"
     gene            complement(9626..10069)
                     /locus_tag="K3072_RS25000"
                     /old_locus_tag="K3072_25000"
     CDS             complement(9626..10069)
                     /locus_tag="K3072_RS25000"
                     /old_locus_tag="K3072_25000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001074379.1"
                     /translation="MAKIYQFPQGDERGKFREEIARERKKRFAVKTGSTFVKWLGWTWF
                     YLRLLVASVLHFISVFVLAILGAFKWAVFWLGGILCVITWYHLDHQLWTPQNLTIPVIT
                     ATWIFGLLAEPLMELLNKTMPWHKLLVPEPAGESTENSSETSQ"
                     /name="hypothetical protein"
     gene            complement(10073..10915)
                     /locus_tag="K3072_RS25005"
                     /old_locus_tag="K3072_25005"
     CDS             complement(10073..10915)
                     /locus_tag="K3072_RS25005"
                     /old_locus_tag="K3072_25005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435061.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000435063.1"
                     /translation="MEQIKLHKQGGAAVIIIPASMIENTGWEDGTLLDVLEINEALHIR
                     RKTGSGALATKSCPSLFSSTMRHVNYDKIIRYNSGLNLLVNELSFSARRVFFICLYYYF
                     ENKLESDKSLLIRADKYAEFVGVDRSVAYKQMKDAADFFSRNKKLITHCDYISNEGLLR
                     VMFSSKTINYITAIDARKYQVTELPLKSALSLQGRYSWPLYQLIKFSHLKSFTIGVDEL
                     KKEIGYIQNQKFSFFKRDGINIAIDEITERTDVKNIKCVNAERQGRRVSKVRFEIEMR"
                     /name="replication initiation protein"
     gene            complement(10936..11775)
                     /locus_tag="K3072_RS25010"
                     /old_locus_tag="K3072_25010"
     CDS             complement(10936..11775)
                     /locus_tag="K3072_RS25010"
                     /old_locus_tag="K3072_25010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001722379.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_001546350.1"
                     /translation="MNLLSVTKKTKIRHRNEINSTFSSLPLSARRILFMAMAQIDSREE
                     LSEGATFRITAREYAFIADIDVTGAYRQLKEGAEELQASVIRIPRNQLLTAQGNQSSGH
                     TKKRGKLPSDAVRLMNLTAFCDYVESEGYIDIAFSHVIEPYITMLKDSYTTQVLISSVR
                     LADQNSNMLYQFIRKQYSSGKKTFFDIEVDVLKDELELFRIDNGEKVYLYQNFKDFNKV
                     FLQKNIEKINQYTEINHLEVKIIERVARRASKLRFSYKIDKESEGLDTRIPYGFRGA"
                     /name="replication initiation protein"
     gene            12997..13248
                     /locus_tag="K3072_RS25015"
                     /old_locus_tag="K3072_25015"
     CDS             12997..13248
                     /locus_tag="K3072_RS25015"
                     /old_locus_tag="K3072_25015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000121741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="WP_000121743.1"
                     /translation="MSYQILTTTAASITDLKKNPMGTVAEGEGDAVAILNRNEPAFYCV
                     PPKLYAYYRELAEDAELNAVADERMKNPEIVKVNLDDL"
                     /name="plasmid stabilization protein"
     gene            13238..13519
                     /locus_tag="K3072_RS25020"
                     /old_locus_tag="K3072_25020"
     CDS             13238..13519
                     /locus_tag="K3072_RS25020"
                     /old_locus_tag="K3072_25020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001694627.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_000220560.1"
                     /translation="MTYELAFDRRALKEWQKLGHTIREQFKKKLAERLENPRVPAARLH
                     GHADRYKIKLRASGYRLVYQVIDEKVVLLVIAVGRRESSEVYQIADLR"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            13665..13988
                     /locus_tag="K3072_RS25025"
                     /old_locus_tag="K3072_25025"
     CDS             13665..13988
                     /locus_tag="K3072_RS25025"
                     /old_locus_tag="K3072_25025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001181903.1"
                     /translation="MQNYAKSVATEILRQLGGNRFIVMTGAKSFSYFDENGECGLTFRL
                     PSNFAMKGINLVKIKLDFTDTYQVKFSRVRGAEVKDISRFDNIYCDQLARLFTQETGLH
                     TVL"
                     /name="hypothetical protein"
     gene            14033..14278
                     /locus_tag="K3072_RS25030"
                     /old_locus_tag="K3072_25030"
     CDS             14033..14278
                     /locus_tag="K3072_RS25030"
                     /old_locus_tag="K3072_25030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001550454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000356548.1"
                     /translation="MDKDKIIKKNRGNYSYVIRTMDEDGDTVFHVLKYVKTIDKTKSRK
                     TVRKLIMDEKLNLASLMLLDNWVLCDCLTKGDENAE"
                     /name="hypothetical protein"
     gene            14268..14483
                     /locus_tag="K3072_RS25035"
                     /old_locus_tag="K3072_25035"
     CDS             14268..14483
                     /locus_tag="K3072_RS25035"
                     /old_locus_tag="K3072_25035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001180116.1"
                     /translation="MQNKPTPEEVKNARVAAGLTLKEAADIFGYQLNSWQMKESAGKAS
                     RSLSIGEYQYLLLLANMHPSYRLVKK"
                     /name="hypothetical protein"
     gene            14576..14905
                     /locus_tag="K3072_RS25040"
                     /old_locus_tag="K3072_25040"
     CDS             14576..14905
                     /locus_tag="K3072_RS25040"
                     /old_locus_tag="K3072_25040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000866648.1"
                     /translation="MKVLTFKNDTVSVGDIFVSSWGYEQTNVTFYQVLSVHGKKTVTVR
                     EIRANSEYTDSMVGFKTPVLNDFTGECFKRQIKDFGDELAIKIEDFETAYKTLPEEKHR
                     FSSYY"
                     /name="hypothetical protein"
     gene            14948..15127
                     /locus_tag="K3072_RS25045"
                     /old_locus_tag="K3072_25045"
     CDS             14948..15127
                     /locus_tag="K3072_RS25045"
                     /old_locus_tag="K3072_25045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_071526261.1"
                     /translation="MEREFSAKASLNRNIKFWFEQCGLSKERVIHCIDNWYDLAYPPSE
                     QEKVRTGESKKRSN"
                     /name="hypothetical protein"
     gene            15213..15362
                     /locus_tag="K3072_RS25050"
                     /old_locus_tag="K3072_25050"
     CDS             15213..15362
                     /locus_tag="K3072_RS25050"
                     /old_locus_tag="K3072_25050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000003880.1"
                     /translation="MSERILSAINDVEKGGRPVFPLMPFHVFPEYMALLRKALEKKTQK
                     RTDK"
                     /name="hypothetical protein"
     gene            15375..15647
                     /locus_tag="K3072_RS25055"
                     /old_locus_tag="K3072_25055"
     CDS             15375..15647
                     /locus_tag="K3072_RS25055"
                     /old_locus_tag="K3072_25055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001547192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000160399.1"
                     /translation="MTKHDFVSFVSGELRQGAVRFSLAFNSKGEIVLHWTNKAGIRVWR
                     ILSGNRGKKPSKANLERMSNFRRWLFDARQGMEGYTQQPEQSNLS"
                     /name="hypothetical protein"
     gene            <15878..16231
                     /locus_tag="K3072_RS25060"
                     /old_locus_tag="K3072_25060"
                     /pseudo=""
     CDS             <15878..16231
                     /locus_tag="K3072_RS25060"
                     /old_locus_tag="K3072_25060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015059103.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0030527 - structural constituent of chromatin [Evidence
                     IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS family nucleoid-associated regulatory
                     protein"
                     /name="H-NS family nucleoid-associated regulatory protein"
     gene            16286..16693
                     /locus_tag="K3072_RS25065"
                     /old_locus_tag="K3072_25065"
     CDS             16286..16693
                     /locus_tag="K3072_RS25065"
                     /old_locus_tag="K3072_25065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001546356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001546356.1"
                     /translation="MSLTLPLMYFQTGADLSKITHHEVHYQDGFVQQAWLQPEIQLFVV
                     CIARKKGSRREIKGGMAVLTSIPASNGAELAKALDNVMRQSDELRPLAGKDENVFIPAR
                     IGISGEEPPTEQELLSVFYQQCLKHGSWGSA"
                     /name="hypothetical protein"
     gene            16950..17414
                     /locus_tag="K3072_RS25070"
                     /old_locus_tag="K3072_25070"
     CDS             16950..17414
                     /locus_tag="K3072_RS25070"
                     /old_locus_tag="K3072_25070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001443073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001443073.1"
                     /translation="MNMTARNAGLSFRSPDDDDSHRTRYSELQQAFDFYNQRLFDGELP
                     ECLITFQRVTQDLFQGKFALSWFDRFSVQVEQQKEMAAVIEQWRETIAQAHQNAEPGLI
                     LKRCCQCHRRTGAMITICLLRLLRTSQKGTKSNISVGVWCCCLGEVRTEY"
                     /name="hypothetical protein"
     gene            17895..19022
                     /locus_tag="K3072_RS25075"
                     /old_locus_tag="K3072_25075"
     CDS             17895..19022
                     /locus_tag="K3072_RS25075"
                     /old_locus_tag="K3072_25075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="WP_000417394.1"
                     /translation="MEKYKCPLNATLYRVAYKSYLRGLFMDYILGRYVKIARYGSGGLV
                     GGGGKEQYVENLALWENIIKTAYCFITPSSYTAALETANIPEKDFSNCFRFLKENFFII
                     PGEYNNSTENNRYSRNFLHYQSYGANPVLVQDKLKNAKVVILGCGGIGNHVSVILATSG
                     IGEIILIDNDQIENTNLTRQVLFSEDDVGKNKTEVIKRELLKRNSEISVSEIALNINDY
                     TDLHKVPEADIWVVSADHPFNLINWVNKYCVRANQPYINAGYVNDIAVFGPLYVPGKTG
                     CYECQKVVADLYGSEKENIDHKIKLINSRFKPATFAPVNNVAAALCAADVIKFIGKYSE
                     PLSLNKRIGIWSDEIKIHSQNMGRSPVCSVCGNRM"
                     /name="ThiF family adenylyltransferase"
     gene            19019..20233
                     /locus_tag="K3072_RS25080"
                     /old_locus_tag="K3072_25080"
     CDS             19019..20233
                     /locus_tag="K3072_RS25080"
                     /old_locus_tag="K3072_25080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001090465.1"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="WP_001090465.1"
                     /translation="MNTANILSVNYGAYNAIRMLIGVYHAAFLISTGVTISQLAVLQIV
                     FSVTVLILDFPLSVIADRFYRKQVVVSGVFFTILFYPLCIQSPDMLALVFSEIFYAIGI
                     CCISGAIEGWVLSALDGRNEKFTLCAHLCERVSSFGSVITGAVGILVVYFYDSYKSGYI
                     VSFFLMFVVFIVFLCVKTNGSGGEKEARDSIIKQAKESIGLITGSYNGTYFLSITCMFT
                     IGIQVIYHFWQPIMLSGESIGSLSKRELITLLMCHIGAFSMQYIANYLMPKIDVRCKLY
                     ILVCTLCSFLSSIACILLFMLITDNKVVLGVAIFSIIHGMISTIPVGAQNIFISRLNGN
                     YKNIISGALGLVSLSCRVASISVLGVISVLPGNMPVTTYIFISAIACVLCGCLFLMWSF
                     KKEMV"
                     /name="MFS transporter"
     gene            20230..21033
                     /locus_tag="K3072_RS25085"
                     /old_locus_tag="K3072_25085"
     CDS             20230..21033
                     /locus_tag="K3072_RS25085"
                     /old_locus_tag="K3072_25085"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152798.1"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]; GO:1904047 - S-adenosyl-L-methionine
                     binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_000152799.1"
                     /translation="MTIKHAEELTEEVILNMNYPDFVALMQQDNTPPGAEYTIDYWIKH
                     GCINKKSHLLDLACSTGFSSRECFKKEGASAEGIDISESAVMVANEKAKKLKANNLLKY
                     YVADACDLPFEDNSFTHVLGGCNFAFIQNRLIALNETHRCLNHMGSMCISNFYYRRKIS
                     DKLINDVYNAINFRPNPLWTLEYWHQFFSERFTLVSEENHEMESQSEDELKADIYDYIF
                     NRNEFTKGLNGSLQNVFFERFLKIRRPLNIQRDYQGVTLQIWRKK"
                     /name="class I SAM-dependent methyltransferase"
     gene            21018..22787
                     /locus_tag="K3072_RS25090"
                     /old_locus_tag="K3072_25090"
     CDS             21018..22787
                     /locus_tag="K3072_RS25090"
                     /old_locus_tag="K3072_25090"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231998.1"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]; GO:0008080 - N-acetyltransferase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_000057520.1"
                     /translation="MAQKITPSKIVKHARELIIKGIESGENSFVIFDVDGALERLDHYR
                     CQLKSFFPNSSIAYSYKSNNLAQWCQIISGKGLYAEVCSVDEMNLAKRDGFKRIVFDGP
                     LKKTSELLKAIEIGALIEVDNIDECKRLNELCKLHKLTCRIHLRLSHYYDDNLSRFGLS
                     ESEAINLLEMLISKSEYLILDGFHLHVGSNLPNAEKICKAIIQYHELILRYMPDDGTLN
                     LGSGIPADSFSASSDNPTPCPEVFFSSIYDTIKNCFGTVCDKWNYIFEPGRHLVEDFGY
                     FIGKVISTKNRYGVKVAQTNIGINWIPSIRNWDHSFTLFHNHNHISDDKSDEYIIAGFN
                     CFECDCLFPSVILPSNLSDYLFSVRGCGAYDMQTGNQWTRNLYAVYTITNDVVNISRIH
                     RRELDFRKYDVSLTPSGIKVNDEITLLYPALKYAEELYLLINQNKINFIKSMAWPAFVN
                     NISDSVSFIEQSMIDNQNEKALILFIKYKTKIAGVVSFNIIDHANKTAYIGYWLGANFQ
                     GKGIVTNAINKLIQEYGDSGVIKRFVIKCIVDNKKSNATALRCGFTLEGVLQKAEILNG
                     VSYDQNIYSKVIG"
                     /name="GNAT family N-acetyltransferase"
     gene            complement(22844..23878)
                     /locus_tag="K3072_RS25095"
                     /old_locus_tag="K3072_25095"
     CDS             complement(22844..23878)
                     /locus_tag="K3072_RS25095"
                     /old_locus_tag="K3072_25095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="WP_000973426.1"
                     /translation="MMIQSHPLLAAPLAVGDTIGFFSSSAPATVTAKNRFFRGVEFLQR
                     KGFKLVSGKLTGKTDFYRSGTIKERAQEFNELVYNPDITCIMSTIGGDNSNSLLPFLDY
                     DAIIANPKIIIGYSDTTALLAGIYAKTGLITFYGPALIPSFGEHPPLVDITYESFIKIL
                     TRKQSGIYTYTLPEKWSDESINWNENKILRPKKLYKNNCAFYGSGKVEGRVIGGNLNTL
                     TGIWGSEWMPEILNGDILFIEDSRKSIATIERLFSMLKLNRVFDKVSAIILGKHELFDC
                     AGSKRRPYEVLTEVLDGKQIPVLDGFDCSHTHPMLTLPLGVKLAIDFDNKNISITEQYL
                     STEK"
                     /name="S66 peptidase family protein"
     BGC             7970..24185
                     /name="RRE-containing"
                     /gene="RRE-containing"
                     /tool="antismash"
     Typing          complement(9624..10069)
                     /name="IncX1"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="94.855"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gaaagaaaaa tccctcaaat gaaggggaaa aaacggaagt acagctgaac gacaggcaca
       61 aaaaaacccg actggtaatc gggctttttt gtgttttcca gccctgagtt ggtggctctg
      121 actggagaag gttactctac acctaacgtt tacattttat tcactatggt gctgtaaagc
      181 aactaaatgt ggttaaggaa ccacatttag tggtgtaacg ggtgttttgt gtagcgtata
      241 atcagtcagt tagtcatgta gttgacttgc aatcctgctc ttcccgtatc tgcgggtatg
      301 aacgatttta aagtcctggc tggataaaca ggtggtgctg tattcggtgc tctggcagga
      361 ggaggtcact ctacacctaa caatgcgaga gagccgttgt gacaggcagt gtatgagtaa
      421 gcaacggtga tttcctccag ttttactgga gaaacggatg attaatttgt taatcatcgt
      481 tctcagggct gtggtcgccg ttgcaaacgc gctgattgca attctggaac tgattcgcca
      541 gttcatcgac tgatgacagc ggaaacgtaa ctaagggcag gaagtgaacc gcttcctgcc
      601 ctttaacaaa ggaggattta tggattttat gagcattttg gggcgctgtt tacttcttcc
      661 tttccctgtt gcgatgtttg tcggttgcct gtttctaggc attgatgatc gttttactgg
      721 aatgttcatg agttttattg tcggttgtct atcgtggtat atcaccaagc caaaaccgca
      781 aaaggctgag gtcgcgtaag cggccttttt tacgcccctc gtttaattcc tcgcccgact
      841 tggatataca ctcattctgt ccagaaatag tattgcggct aatcaagcca attcctacgt
      901 cttttcgctg ttgcacgatc taaaagaaaa tatgggaaaa tttcatgaaa gtatggtact
      961 aaagggtctt taattccttt atcttgttcc ttcaactgca cagtatctcg taaaaaccaa
     1021 caagccggtt gtttaaaaaa cgctcttagc gtaggatgtt ttccattttc caagtgaaac
     1081 ccaagtacga tgcccgcgaa aaagacagcc ctcttatgaa gagggctgtt atctgatata
     1141 ggcttgttat ggtctcactc ttgattaatc aggtgtatgt acaaccttgg tgtacacaat
     1201 cgattatgca gcttgatgat ctgaagtgtt accggaagta tcttcggttc gttttttgtt
     1261 tgtgatggat tcacttttat ctcgcaaggc tgagtctatg acgttaaaca ccttttccca
     1321 ccgagaaatc caaccgcata taggttgaac acgacatctt tccaggaaga aatttaataa
     1381 gttagttttt ttattatctt gcactttgaa tggttcaatt acatcatcgg catcaacaga
     1441 ttttcctccg ataaaccacg acggatgggt ttccattgcg tcagaaatga aatcgtcagg
     1501 gaagaggcct tcaatagcaa aaccacttct tacagaaata tagtctttat ttgactcaaa
     1561 tctaatttgt tttttaccaa agtagctttg taatctggtt ctttctttga ccccagcttc
     1621 atcaccgtca aaaacagata ttacggggac atctttagaa ataaactcgt agcacccttt
     1681 caagaatcct ccaagttgac tgactccacc aaactcatca actttagcac tcctcagaaa
     1741 aggccatctg ttcttaaact catcatgttc agatgtcaat ttcaatattg attctatata
     1801 ttgtttgtcg gtgatacctt caacgaaaac tgcactactt gatatgttaa agaaatcaga
     1861 aaatctgacc ccaagatttt ctcttatgct tgcaactgca ttaaatcttt tttcatgctt
     1921 tttatctttt gtaacaccgg cgtcatcttt atataactca atgatcttac ttggctcatc
     1981 actgacaaat gataaggaat gagttgtaat aagaacataa gcaacatcca tcagtgattt
     2041 gaaaatgtga ttacatgacc ggcctaatga gggatgcaag aaagactcag gctcctcaac
     2101 catccaaatc gttttcttac ctagagtaag ttttctctct gaaatagatt taaatgaaga
     2161 aaataaagat aagcattgta gccccatacc tttactcgat atcacattct caatagtatc
     2221 ttttattgaa acctcaaagc gaccaaataa ctcatcaaga gatggcggag ctttaatcat
     2281 aaagctacag tcatctatac cgcttagaat catttcattt gttatctttt cagacacttc
     2341 caacagttta tcatgaatca cttgaaccga tgttttcatg gctgaagcta cttcactcct
     2401 aacatatgga actaatagat tatgatatat atcatcaata ctttttgacg atggtatata
     2461 cacacactca aaactagaaa gtattttttc tatgaacctt ctttcaacag atgtatacat
     2521 ggaggaagtt acttcaggtt tcctcttgta acctttaaag acagtgtaga agtaattgtt
     2581 tttattagat attgtcagat gtacggtcac ttcgttttga ggtgaactta acctggagtc
     2641 atcaatcatg ttaaatagct gcaaatatct atctctcaaa cttagctttc tgcctcttga
     2701 ttgagttggt tttgattctt gttgtttaga gctgccatca tcaaatgaaa tagaattact
     2761 aggttcttct tgccccccta aaacaccaag ttcaataatc gagtcatcat cgtcatcatc
     2821 atcgtcttgg ctcaaatcct cagagacatc atctagctca ctttcagaaa aagtaaatct
     2881 tacagcaaaa ctagtttgtc cttgcttaac accatgtggc ttatcttttt catagtcata
     2941 taagtcagga ttaaattttc cttcaaaaaa aaccctcata gcttttaata ggtttgtttt
     3001 accactgttg ttttgcccaa caatggttaa tccattaaag ttatcagagg atatctcccc
     3061 tgaaatagac ctatactgag aaactttaaa tgatactatt tccatttttc ttcctacgat
     3121 agaatgttgc tcggattatc gacatttttt cccaaggctt taactgtcct tcgctacttg
     3181 gagaaatggc tcttcctcca ctgttctgct ttattttcgc cagaaagccc accatgcatg
     3241 ttgtttgtcc tgaagtgctg ctttatcctg aagcaattca gcactcactg ccccctgaag
     3301 cacagaaacg gcgtttctcg cggcattgcg acaggaatca ataacctctg gttcgttggg
     3361 ctttctgagc aggataaatt gcgatacttt ggactgagta tcaaaagcat agattcgcaa
     3421 ttcaggggag gatgtcaggc ttacaatatt atgtaaccgc atataattgg tgtagtcctc
     3481 gctacctgga ttacatgatt cataaagata tttctgcatt agcgtttgcg atgaagaaag
     3541 aaaatctata tagcggtcag tttttttatc tatatcccgc agtcgctgag ctattgcatc
     3601 ttttcttatt tcgtggcagt gtgttaattt cagtgtaatc cagccaccaa caatggtgat
     3661 taatgcaccc agcccaattt taacggcatt atcagccaca tctacccact cagttgccat
     3721 ctgttacacg ttcttcctgt gatgatcatg gtcgctagta taattctccg gctgactgga
     3781 catacagcat tttctgtcta gcaccgaaac gttataaacc tttgttcaaa ttcctgatct
     3841 ctggcatcat cttttcgtac atcttttcag ttgagttagc gcaataactc tgtaggtatt
     3901 tatagttttc ttcgaatttc ggaaggtttt tagctaaagt gatctgttta ggtaaggttc
     3961 cggtagaatc gttgaccaca tcaaacacta tcggattatg tttatgatct tcatcaacta
     4021 attttaatgt agctacaaca gggcttttat ccattgcccc gttaactagt tgtctaattt
     4081 ggaattttct cgcaaaaata aaattaatta gagatggact gtcactatta aaagttatat
     4141 tccacgtcaa aggcattgca tcacataatc cttctgagat aaattcacca tcaatagaac
     4201 catctttatc aacaaataat tgtatagtca taattgattg cggtttatct agtccaagat
     4261 ccccactatt aataatatat tcagcatctg ttgaccattt tccggtaagg aattctcttt
     4321 gataaagagc agcattcaat tcatttttat atggtaggta aagtcccact gctgcgataa
     4381 ccaccccaaa tgcagtgcat aaggttgtga ttcgtccact catttttttc ccttatcttc
     4441 atatgtaaaa tttataacca attgtacatt aatagcctcc tttagtaatc ccccgcccat
     4501 attggacatt ttgttttttt gtttagactc aattagttac aacattcata tgtttagttc
     4561 ctttatcctg tgccctgttc cggcatatgt gcccatatcc taggttattc aggataatcg
     4621 cttccttttc gtcctgcccg gcgttcactg gtgtttacgg cagggaactt aaccaccgga
     4681 cgggtggaaa catgtggatt tgtgtgtggc tggaggttta atgctaatgt acgcgtacac
     4741 tagcattaat ggggagggag ttaactctct tttattctgg atgccttgat tccctcctga
     4801 tacagacgct ttacccgttc aatttcgtcc agcgttgccg cccagtgctg tcttgccgca
     4861 tgacgatatc tggcagccat tttttccacg gcctccaggg tgctgtcgtt gctgcggtgc
     4921 tgccgctcct tatccccgaa taattccaca atcagccact ggctccccgt tctgccaaac
     4981 aacgcattgc acaaccgttt aacggccagc ggtgttaaat ccgggtcagg gtcatatgct
     5041 atggtggcaa aaataaaccg cagcatttcc gaggttttgt aacgcttcac cgctgccgcc
     5101 agacgtgcgc cacgttgcgg ggcttcccag cgttcatcgc tgtatctggt cagttctgaa
     5161 aggaaatccc tttcaagatt ttcagcggtg taacatctgc caccgagaaa catacgcata
     5221 gcttctctgg ttttgtctct catgtattat tctctggatt aatgctaatg tatgcgtaca
     5281 ttagctttaa gccgtatcaa tagaaacaaa tatcatggtt cgtagaacct ccatacagcg
     5341 aacttttgca gaaactgagc gggggtatca gggattcccc cccctgagcg cgtcgtttat
     5401 acacggaatt tattacgtgc atacatcgct gtcgtgccct gtatttcaga aacactcttc
     5461 gggacagaca caaacgtgtc tttccgtgtg ccattgtgtg tgaagggctg attcagtccg
     5521 ctgcctcttg cgcgactttc cctgccctgt cgttcattca tcatggacaa aaatgcatta
     5581 tcggaaaaaa tgtccaaaat ttttttgtga tcagaatttt tgttgtcgga cacacctttg
     5641 ctccaagtca taattgctga cacatcccca aaaaacagga gcggagattt aaaaattgag
     5701 tcacttaccc cgccaacatt ttccagattt cacgtagcgc accaccgcta ctgcatccat
     5761 caacaaaaaa tgacgttttt ttaattactt tgtatgctgc aacttactga aaaaacggga
     5821 ttcatgataa tgtcggtaac ggcatcgttc tgggggcgct aatctcgctt cttgaactga
     5881 ttcgctacct tctccagttg atgggctgat ggcggagacg taactaaggc cgggggctaa
     5941 ccaccaccgg cctttaataa aatcatattt tagttacaac attcaaatgc attaactaaa
     6001 caccacacac ccaacctcct gagttaatat cctgcctttc agatatatta gccccccacc
     6061 ccctctactt actggatttt tgcccggttt tacgttttag cgcactgctt attgtgccac
     6121 ggctgcaccc tagcactttc tgtacctgtg tccaggagct accgctttct atcaacctga
     6181 taattgcatc atgtctggct tgattaggtt tacgcccttt atatttaccg tctttccttg
     6241 ctttctctat cccttgtttc tggcgttccc gacgttgttc atagtccctt ctggcaactg
     6301 cggccagcat atccagcagc atatcgttaa tggctgcaaa caaccggctg tcaaactcac
     6361 tcataccaga attaatccat gtcgtcggca cattcaccgc cataacccga atgtctttct
     6421 gccggatcat tttcttcaac gtattccagt cttcccctga cagtcgggaa agtctgtcca
     6481 catcctcgat aagcaaaatg tcattttgct ggcaatctct cagaagacgg aagagttccg
     6541 ggcggtcaag acgggagccg gattcattct caatataata gctgcaaatg atcaggcctc
     6601 tttccctggc aaaagcctcg atagtttcca gggcacgcga agcatcctgt tctgctgttg
     6661 aagctctcag ataagcgcgg acaaagtttg ttggtgcatt tgaagtcata ttagagaacc
     6721 agttcgcata aggtcacaca actataccca aaatgaacca gaaagtggat cgacaggaaa
     6781 ggcacactct aaaagaacca gaaaacagac ctctggtcat aaagtgacaa tgtcacatgg
     6841 aaatttacaa cataaagatg atgtaaagac aagtgctgat ttatcatata aagacactgt
     6901 aaagacacac taatctttac aatataaaga caacataaat acataattgt ctttatttgt
     6961 gctttacatg gtaaatccta tgtaatataa agacactgta aagacaaaat catctttacg
     7021 gaaaacacac aatgtaaaga caagacgatc tttacataat ctttacatcg taaagagagg
     7081 aattctcaaa tgggtaaaat cttgcttgtc gtatcagata agggtggtgt aggaaaaagt
     7141 acctacgtgg ctaacacagg ctcaatgctg gtcaataaag gtaagtcggt aattatcctc
     7201 aagacagata aaaaccacga tctgttgagc tggaacgaaa agcggacaga taacggctta
     7261 ctcactatcc cggttcacgc agcttacgga aacgtcagca atgaaattaa gcgacttagt
     7321 aagctgtgtg aagtcctcat tgtcgattgc cccggccacg acagccagga gttccgtagc
     7381 gccctgacag tatcagatat cgtggtaaca ctggttaagc cgtcctctga tttcgaaagc
     7441 gaaacactga ccagtgttac agagaaaatc cgcaccgctc agaaagctaa cgcagccctg
     7501 gaaccgtggg tgctgttcac cagaatcaac tcagcaaaac cccgccacag aaaagcggcc
     7561 attgatctgg ataaattact gcggtcggac aacatctgga ttcaacctct taaaacccgg
     7621 atatccgagc tggatgtgta tgaaagcgcc tgtaatgaag gggcaggggt acatgacgtt
     7681 agccgggcat caagcctttc aacagcgaaa gcacagattg aactagtagc gcaggaaatt
     7741 ggaattttat agtaatatca ataccatcta taaatcttta cattgtaaag acaatataaa
     7801 gacagtatga tatttactat taatgcatac cgtacaaggg gaaattgtca tggctttaaa
     7861 actaaaccgt ccgaacatcg atgaatctca gcaaccagca acaaacgcag aaaccgcgcg
     7921 ttttatctcc ggcgctacca gagcgcctgt agtgggtaaa ccaaagttga tgaacttcag
     7981 actttcagcc cattttgagg acatactgga agctgaagct atcagaacag ggcagagcaa
     8041 aacaaccgtt ctcaaagcag cgctggcgat gtacaacagc caggatgaaa acataaagaa
     8101 tcactggtta ctggaatcgg caaaattcta accatagaag tatggatgat tatctatgag
     8161 atatttaacc gaattaatct gtcaactcta caggttgaca gatcaccata aactgaccgc
     8221 tgcaacgttt aaaaatcttg ctgatattaa gttagttgaa cctacagcgg atgcagacac
     8281 catattgcag cttgaaaata tatttagcga atactcacta agatatattg acagggatct
     8341 ggctgaaatt ctgagtaaca taataactac agataaaaac cactctctgg attttgattt
     8401 taacaagata cagtctctga ctgcctcgaa aagtttcggt tgtggatgga acaaagtaat
     8461 aaatggtagt tggttcaaaa acctttattc atggggggaa gggatgtatc ccgccaaaaa
     8521 cctgaaagct gaaaacattt cagactggga ggataatata tggcacattg agcatgaagg
     8581 tttcaaccct cgcgatccta ttaatgttaa atattactct tggcttgacc gatatgtagc
     8641 tttaaacagt ggtggttcac atcatgcagc aatggttgta tatcaatctg tcagagacaa
     8701 attagagtat aaaagagaag cggttattga acaactgagc ataaattcaa acaccgttga
     8761 aatacttggc cagaactact attcattcat attccagata aaacacccta gtaataagac
     8821 agaaaattat acatcagaat atgaatttac agatgcttta aaagactttg gacaaaatag
     8881 gcataccaca cttaaacctg ttaattacgt ttctaacata aaattagcat ttattcccaa
     8941 agatgcttta aaaacaaaca gcgagacatt ccgcaactgg ttttattctg caattagcta
     9001 cgggaaaata atatcactcc ctgattatct gaaaaatcca gcacattatc atacatatca
     9061 ttactcacat gaactagact cgataacact tggcaaccca agcagaaaat ataaactgag
     9121 aggagattct tagcttttat ataaaaaacc aatgttatca tttgtcagaa gatcggcgag
     9181 ggtagtacat tcaagaacca caatatttgt tccttccaac aaactggcat caggtatctt
     9241 atcgaagctg ataatcatca ttggcttgcg ttgtgttaaa tcaaagatta ctaatggaag
     9301 tattacactg ttaattaatt caaactcttt aaagaaagca tcagtgccat actcactggc
     9361 tggaaaaaga atctcactta atctcacacc ataaaaaaca tggtagtttt ctttaaggtt
     9421 atcctttaaa atattaacag ccttcgcata tttatcagta ataaattctc tcacctgata
     9481 tttcataaaa ttctccgaca agaaccgact gtaggtcacc gggcaaacgt tgcggaatgg
     9541 cgtcagagac gtcattttgc ggtgtttgcc ctatcctgca tcgcagtgaa aaggcagggg
     9601 ctggcataac gactaagtag cgtcattact ggctcgtctc gctgctgttc tctgtgcttt
     9661 cgcccgcagg ttcgggaacc agtaacttgt gccagggcat ggttttgttg agcagctcca
     9721 tcagcggttc agccaacaga ccaaaaatcc aggttgccgt aatcaccggt atagtcagat
     9781 tttgtggcgt ccataactgg tgatcgagat gataccaggt tatgacacac agaatgccac
     9841 ccagccagaa cacagcccat ttaaacgcgc caagaatggc taacacaaaa acagagataa
     9901 aatgtaaaac actggcgacc agaagacgaa gataaaacca ggtccatcca agccacttaa
     9961 caaaagtgct ccctgttttc accgcaaaac gtttcttacg ttctctggcg atttcttccc
    10021 tgaatttacc gcgttcgtcc ccttggggga attgatagat tttagccatg agttacctca
    10081 tttcgatctc aaaacggact ttgctgactc ttctaccctg cctttcagca ttaacacatt
    10141 taatgttttt aacatctgtc ctttctgtta tttcatcaat agctatattg attccatctc
    10201 ttttaaagaa agaaaacttt tgattttgaa tataacctat ttctttctta agttcatcta
    10261 cacctatagt gaaagattta agatggctaa attttatcag ttgatataaa ggccatgagt
    10321 atcttccttg aagagacaaa gcagatttta gaggaagctc ggtaacctga tatttacggg
    10381 cgtctatcgc tgtaatataa tttatcgtct tagacgaaaa cataacacga agcaatccct
    10441 cattcgaaat atagtcacaa tgtgtaatta attttttatt tcttgaaaag aaatctgctg
    10501 catccttcat ttgcttatat gcgacagaac gatcaacacc aacaaattct gcatacttat
    10561 cagcccggat caatagcgac ttatccgatt caagtttatt ttcaaagtaa taatataaac
    10621 aaataaaaaa gacccttctt gccgaaaatg acagttcatt aactaacaga tttaatccgc
    10681 tattatatct aatgatttta tcgtagttaa catgcctcat agtagatgaa aaaagagaag
    10741 gacaagattt agtagctaaa gctcctgatc ctgtctttct tcttatatga agagcctcat
    10801 ttatttctag tacatccaat aaggttccat cttcccatcc ggtattttct atcatactgg
    10861 caggaatgat aattactgcc gcaccacctt gtttatgtaa ttttatttgc tccatagtgt
    10921 atttaccttt atatattaag cacctctgaa accatacggt attctggtat caagtccttc
    10981 gctttcttta tctattttat acgaaaatct tagctttgat gctcttcttg cgactctctc
    11041 aataatttta acttcgagat gattaatctc tgtatattga tttatttttt caatgttttt
    11101 ttgcagaaaa accttattaa aatccttaaa attctgataa aggtaaactt tttcgccatt
    11161 atctattctg aataattcaa gttcatcctt taatacatct acttcaatgt cgaaaaatgt
    11221 ctttttacca ctgctgtatt gtttcctgat aaactgataa agcatatttg aattttgatc
    11281 agcgagtctt acagacgata tcaaaacctg agtagtgtaa gaatccttta acatcgtgat
    11341 atatggctca atgacatgtg aaaaagcaat atcaatatat ccttcacttt caacataatc
    11401 acaaaacgca gtcaggttca taagcctgac tgcatcagaa ggtaatttac ctctcttctt
    11461 cgtatgtcca gagctttgat tgccctgagc tgtgagaagt tgatttcgag gaatgcgaat
    11521 aacactagcc tgaagttctt ctgccccctc ttttaactgc cggtaagcac ctgttacatc
    11581 aatatcagcg ataaatgcat attcccgagc cgtaatacga aaggttgctc cctcagataa
    11641 ctcttcacgt gaatcaatct gcgccatagc cataaacaaa attcttctgg cagacaaagg
    11701 caacgatgag aatgtgctgt taatttcatt tctgtggcga atttttgttt tctttgtaac
    11761 gctcagtaag ttcatacatt acctgtgttt tttaagtcct gatggtgaaa tcataaccac
    11821 aaaagcggaa atgtgtaaag tggtttatcc accttataca tttccaccaa aacacagatc
    11881 acatgaaaga atttttatca tttatattca atatgataga aatgcgcagg tatccacctt
    11941 ttaactttta ccgttggatt ggaacgctat aaagaactaa agaaatgaag atgcaaagag
    12001 atgaatatct gaataaaaac agtaaaatgc gtacccatcc acctttcagt gcgtacccat
    12061 ccacctttca gtgcgcagcc atccaccttt catgaaaatt acagtgcgta cccatccacc
    12121 tttcagtgcg tacccatcca cctttcattt tgaggcgaca aaaaacaaca cctatcttaa
    12181 tgaaattatt gataaaaaag ctggcacaat gtttgcagaa taagttaaag taagttaaag
    12241 atcttaaagt agatctaccg atctacattt aagatcttaa aaacaagaag tttaataagc
    12301 aaaaaaacac aaaaaatctg tggataactc tgctcaaaac aaaaaattca cagtgcctgt
    12361 ggataacttt gcgtaaaccc agaggacaga tcactctgaa ccaggacaac cacacataaa
    12421 aacaatatgc tcgcttttta accactgtgc gtaattgcct gatgttatcc ctgtgctgtt
    12481 ccgcttcctc gctcactaac tcgctacgct cggtcgttcg gctgcggcga gcggtgtctc
    12541 ctttctcaaa accagaagag ttcagatcat acgatccgtt gattgatcct ttttggatct
    12601 tccactgaga agccctgaat cgctttctgc agcttcgttc agtacaacca taagaaaatc
    12661 catgtgaaat cgaaaaaatc gctcagaatg cgatacagcg cgttttagag ggtatttaca
    12721 aaacagtcgt tgccttgagg aaattttgat caagattgaa ctcctatccg gatcatagca
    12781 acaaggccgc taaaaagcgt tgagcggcgt taaaagccgt taaaccgtag ctgactacaa
    12841 cgaaacggga aaaaacgctc agaacgcgtt acagagcgtt ttaaggcgat gtcggaaaga
    12901 gccatatctc acctgttctg atgtttttct caacataagc acttttaaga gtgcttttaa
    12961 agatgctatt atgccaatga gacaagcgga gggcttatga gctatcaaat tctgacaacc
    13021 acagcggcca gtattactga cctgaaaaaa aatcctatgg gaaccgtagc tgaaggtgaa
    13081 ggggacgctg ttgcgatcct gaaccgaaac gaaccggcgt tctattgcgt tccaccaaaa
    13141 ctttacgcct actatcggga actcgctgaa gatgctgagt taaacgctgt tgctgatgag
    13201 cgcatgaaaa acccggaaat tgtgaaggtt aacctggatg acctatgaac tggcttttga
    13261 ccgtagagca ctgaaggaat ggcagaaact cggccacacc atccgtgaac aattcaaaaa
    13321 gaaactggca gaacggctgg aaaatccacg cgtacccgca gcccggttac atggtcatgc
    13381 tgatcgctat aaaattaaac ttcgtgcatc tggctacaga cttgtatatc aagtcattga
    13441 tgagaaagtc gttttactcg ttattgccgt tggaagaagg gaaagcagcg aagtctatca
    13501 gatcgcagat ttgcgctaag attaatcatc aaatgattga ctgtttacag tcagagcgag
    13561 agcattaaaa atttgcaata cctgcaaatg caggtataat aaaacacaag aaagggaaac
    13621 aggttctctt tcatccagag cccaaagtgg gcgggaggtt aaaaatgcaa aactacgcta
    13681 aatctgtagc cacagagatt ttacgtcaac ttggtggtaa tcgttttatt gttatgactg
    13741 gtgctaaaag tttttcttac tttgatgaaa acggtgagtg tgggttaact ttccgtttgc
    13801 cgtcaaattt tgcaatgaaa ggcatcaact tagtaaaaat taaactggat tttactgata
    13861 cgtaccaggt gaaattttct cgtgtacgtg gtgctgaagt taaagatatt tcaagattcg
    13921 ataatatcta ttgtgatcag ttagcgcgtt tatttacaca ggaaacaggg ttacataccg
    13981 tgttatagat aaaaaggggc attaagcccc ttttttagtt atgaggaata atatggataa
    14041 agataagata attaagaaaa acagaggtaa ttactcctat gtaatcagaa cgatggatga
    14101 agatggggat acggtttttc acgtcttaaa atatgttaag acgattgata aaactaaaag
    14161 caggaaaaca gtaagaaaat tgataatgga cgaaaaactc aacctggcat cattgatgct
    14221 tctggataat tgggttttgt gtgattgtct gacaaaaggg gatgaaaatg cagaataaac
    14281 ctacacctga agaagtaaag aatgcgcggg ttgcggcagg tcttactctt aaagaagctg
    14341 ctgatatttt tggttatcaa ctgaattcct ggcagatgaa agaaagtgca ggtaaggcca
    14401 gtcgttcttt atctattggt gaatatcagt atttattgtt attagcaaat atgcatccgt
    14461 cttacaggct ggtaaaaaaa taacttgcca tacctgcaaa tgcaggtata ataaaacaca
    14521 ggaaagggaa acaggttctc tttcatccag agcccaagct gggcgggagc taaaaatgaa
    14581 agtattaact tttaaaaatg atactgtctc tgttggtgat atctttgtat catcatgggg
    14641 ctatgagcaa accaatgtaa ccttctacca ggttctttct gttcacggta aaaaaaccgt
    14701 caccgttcgc gagattcgcg ccaattcaga atataccgat tcaatggtcg gctttaaaac
    14761 tcccgtttta aatgatttta ctggtgaatg ttttaagcgt cagataaaag attttggtga
    14821 tgagctggca atcaaaatcg aagattttga aactgcgtat aaaactctac cggaagaaaa
    14881 acatcgattt tcttcttact actaattaat caggggggat attccccctt ttagtaaagg
    14941 tctgaaaatg gaaagagagt ttagcgcaaa agcatcatta aaccgaaata taaaattttg
    15001 gtttgagcaa tgtggattat ctaaagaaag agttattcat tgtattgata actggtatga
    15061 ccttgcatac ccaccatcag aacaggagaa agttagaaca ggagaaagca aaaaaagaag
    15121 caattgagaa gttaataaag taaagataaa gatggtatca ggttgtgggg caacctgata
    15181 ccgtgacacc tgattctatt gcgaggaata aaatgtcgga acgcatatta tcagcaataa
    15241 atgacgttga aaagggtggg cgtccggttt tccctttgat gccattccat gtctttcctg
    15301 agtatatggc attactcaga aaagcactgg aaaaaaagac acaaaagaga acagataaat
    15361 aaaccggagg ctttatgaca aaacatgatt ttgtgtcctt tgtcagtgga gaattgcggc
    15421 aaggcgctgt acgcttttct cttgctttta acagcaaagg agaaattgtt ctgcactgga
    15481 ctaataaagc aggaatacga gtctggcgga tattaagtgg taatcgtggc aaaaaaccaa
    15541 gcaaagctaa ccttgaaaga atgagtaact tccggcgctg gctttttgat gcccgtcagg
    15601 gcatggaagg ctacactcag caacctgaac agagcaacct tagctgaata gccgaagccc
    15661 tcccgtattt cgggaggtgc tttctgatat attgcgcggg actgcgcttg cgcttcctgc
    15721 cagaccgttc gcgtagcgaa cctgacggca ctgtccttac cgcattgatc gggtttccgg
    15781 tcgcagacgt acgtatgttc agccatgaca acatcagcct ttttgcattt ttgttgatgc
    15841 tcaagcacta tttatgagcg gcgccagatt cacggcgatg caggaaaagc tcaacgttgt
    15901 tattgaagaa cgtcgtgaag atgctgaacg tgaagcggct gaacgagcag agcgtgaacg
    15961 gaaacgtcag gaactgcttc agttaatcgc cggagagggt ttctcaccgg aagaactgct
    16021 tggcattacc gaagatgcgc caaaaacacg taaaaaaacg ttaccaaaag cgccgcccaa
    16081 gtatcaattt gaagaaaatg gtgaaacgaa atactggtct ggtcgtgggc gtgcaccaaa
    16141 accgattgct gaagcactgg caggcggtcg ctctcttgat gagtttatca tcaaaaaaga
    16201 tgcttccagc tctgctggcg acgaacatta atataataag cctctggttt acgcaggaga
    16261 cttttttgat aaacaggagg atgttttgag tctgacatta ccattaatgt atttccagac
    16321 aggtgcagat ctcagcaaaa tcacacatca tgaagtgcac tatcaggacg gctttgttca
    16381 gcaggcatgg ttgcaacctg aaatacaact atttgttgtg tgtatcgcca ggaaaaaagg
    16441 ctcccgtcgc gagattaaag gtggaatggc cgttctgacc agtattccgg ccagcaatgg
    16501 agcggagttg gcaaaagcgt tggataacgt tatgcgccag tctgatgaat tgcggccact
    16561 ggcagggaaa gacgaaaacg tatttatccc agccagaatt ggaatttctg gcgaagaacc
    16621 gccaacagag caagagcttc taagtgtctt ttaccagcaa tgcctgaaac atggctcatg
    16681 gggcagtgct tgatttctgt tacataaagc agggataccc cctgcttacc tttcttgcca
    16741 gcaatattac gcgctcgatg ctctccctgg gcttgatatt gccaggggat ggcgtcagca
    16801 caacccgggg cacgctgatt cgggtgtgat tctgatttgg gacggagagg tgtattgctg
    16861 gaaaaatatt caccgcgccc ctcagcatga gcgccccaga gtgatagcgg tagatactga
    16921 agataacgtg tttattgcag aaagtggcaa tgaatatgac ggcgcgaaat gctgggttgt
    16981 ctttcaggag tcctgatgat gacgatagcc acagaacgcg ctacagcgag ctacaacagg
    17041 cgtttgattt ctataaccag cgcctttttg acggtgaact ccccgagtgt ctgattacgt
    17101 tccagcgcgt cacacaggat ctgtttcagg ggaaatttgc tttgagctgg tttgatcgct
    17161 tctctgtcca ggttgaacaa caaaaagaga tggccgccgt catcgaacaa tggcgggaaa
    17221 ctattgctca ggcacatcaa aatgctgaac cgggattgat attgaagcgg tgctgtcagt
    17281 gtcaccgtag aacgggagca atgataacga tctgtttgtt gcggcttttg agaacaagcc
    17341 aaaaaggaac aaagtcaaat atcagtgtcg gggtgtggtg ctgctgtctg ggagaagtcc
    17401 ggactgaata ttgaatgcgg cgattgcgag ctgcctttca tcgaaaatta atctctattt
    17461 tcattgtatt tcctgatgct ttctcataag ttctcgtgtc caatcccacc cgaaaaaact
    17521 cagatttcac gtagcgcacc accgctcatt gagcggcttc tcaacgtgac tggtaatcag
    17581 gattattggt ttccaatgta atgaacgatg gatgtatcaa attcttttat tgcataatag
    17641 catatttatt acaaaatgat ttaaacgcag atgattatat tctgtatggt tatttatgtc
    17701 taaatatata aattaataaa ttttagaata aaaatgtaga atcgcaaata atatgattgt
    17761 gctgttcttt ttttgtgaaa taaatctatg tttgtatatt tttataagga atattgtttt
    17821 ttatagtgat aaaaacactt gtgaattaat cacagtaata ggaggcgtaa aatgcgtact
    17881 ggtaatgcaa actaatggaa aaatataaat gtccattaaa tgccaccctg tacagggtgg
    17941 catacaaaag ttatctgcga ggtttattta tggattatat attgggtcgc tatgtcaaaa
    18001 ttgctcgata cgggagcggt ggattagttg gtggaggcgg aaaggagcaa tatgttgaga
    18061 atttagcgct ttgggaaaat attataaaaa ccgcatattg tttcataacc ccatcgagtt
    18121 atactgcagc gttggaaacg gccaatatac ctgaaaaaga tttctctaat tgctttaggt
    18181 tccttaagga aaatttcttt attatacctg gcgagtataa taactctact gagaataatc
    18241 gttactctcg taacttttta cattatcaaa gttatggtgc taatcctgtt cttgtgcaag
    18301 ataaactaaa aaatgctaag gtagtaattc ttggttgtgg gggtatagga aatcatgtgt
    18361 ctgttatact cgcaacgtct ggtattggcg aaattatact aattgataat gatcaaatag
    18421 aaaatacaaa tttgacaagg caggttttat tttcagagga tgatgtcggt aaaaataaaa
    18481 cagaagttat aaaacgcgag ttattaaaaa gaaactctga aatttcggtg tctgaaatcg
    18541 ctttgaatat aaacgattac actgatcttc ataaggtacc agaagctgat atatgggttg
    18601 tttctgcaga tcatccattt aatctgatta actgggttaa taaatattgc gttagagcaa
    18661 atcagcccta tataaatgct gggtatgtta atgatattgc agtctttggt ccattatatg
    18721 ttcctggtaa aacaggatgt tatgagtgcc aaaaagtcgt ggcagatcta tatggttcag
    18781 aaaaggaaaa cattgatcat aagattaagc taatcaatag cagatttaaa ccggcaacat
    18841 ttgcacctgt gaataatgtt gccgctgcat tatgtgcggc agacgtaatt aagttcattg
    18901 gaaaatactc cgagccatta tcacttaata aaagaatagg catctggtca gatgaaataa
    18961 aaatacattc ccaaaatatg ggccgttcgc ctgtttgctc tgtgtgtgga aatagaatgt
    19021 gaatactgca aatattttat ctgtgaacta tggagcttat aatgctatac gtatgttaat
    19081 tggtgtctac catgcagcat ttcttatatc tacaggtgtc actatatctc aacttgctgt
    19141 tttacagatc gttttttctg tgacagtgct gattcttgat tttcctttat ctgtcattgc
    19201 agacagattt tacaggaaac aggttgtagt tagtggcgta ttttttacta tattatttta
    19261 ccctctttgt attcagtctc ctgatatgct ggcattggtt ttttctgaaa tattttatgc
    19321 cattggtatt tgttgtatat ctggggctat agagggatgg gtgttaagtg ctctggatgg
    19381 tagaaatgaa aagtttacct tatgtgctca tttatgcgaa agggtatctt cctttgggag
    19441 tgtgataact ggtgctgttg gaatattagt tgtctacttc tatgattctt ataaatctgg
    19501 ctatatagta tcgttcttct tgatgtttgt tgtctttatc gtttttttat gtgtgaaaac
    19561 taatggcagt ggaggtgaaa aagaagcacg agatagtatt attaaacagg caaaagagag
    19621 tattggattg ataacaggaa gttataatgg gacatatttt ttatctataa catgtatgtt
    19681 tacaattggt atacaggtaa tttatcattt ttggcagcca attatgctat ctggggaaag
    19741 tattggctca ttatcaaaaa gagagcttat aactttactg atgtgtcata ttggtgcatt
    19801 ttcaatgcaa tatatagcaa actatcttat gccaaagata gatgtaaggt gtaaacttta
    19861 tatacttgtt tgtacattat gttcatttct tagttcaatc gcctgtattt tactatttat
    19921 gttaataaca gataataagg ttgttctcgg cgtagctatt ttctctataa tccatgggat
    19981 gatttcaaca atacctgttg gagcacagaa tatattcata agcagactta atggcaatta
    20041 taagaatatt atttcgggag ctcttggtct tgtttctctt tcatgtcgtg ttgcttccat
    20101 ttctgtgttg ggagttatat ctgtattacc aggtaatatg cctgtcacca cttatatatt
    20161 tatctctgca attgcatgtg tactgtgcgg ttgtttgttc ttaatgtggt cctttaaaaa
    20221 ggagatggta tgacgattaa acatgctgaa gaattgacgg aagaagttat tttaaatatg
    20281 aattaccctg attttgttgc tctgatgcaa caggataaca ctcctcctgg agcagagtac
    20341 accatagact actggatcaa gcatggatgt attaacaaaa agtctcacct attagattta
    20401 gcatgttcca cgggttttag ttcacgtgaa tgcttcaaaa aagaaggtgc atctgcagag
    20461 ggtattgata tatctgaatc agctgtaatg gtcgcaaatg aaaaggcaaa aaagcttaag
    20521 gctaataatt tattgaaata ttatgtagct gatgcttgtg atttaccatt tgaagataac
    20581 tcttttacac atgttctcgg tggatgtaat tttgcattta tacaaaatcg gttaatagct
    20641 ttgaatgaaa ctcatcgatg tttaaaccac atgggaagca tgtgcatttc aaatttttat
    20701 tacaggcgta aaatatcaga taaacttatc aatgatgtat ataatgcaat aaatttcaga
    20761 cccaatcctt tgtggacttt ggaatactgg catcagtttt tttctgaaag atttactctt
    20821 gtttcagaag aaaaccatga gatggaatct caaagtgaag atgagttaaa agccgatatt
    20881 tatgattaca ttttcaatag aaatgagttt acaaaaggtt tgaatggttc acttcagaat
    20941 gtattttttg aaagattttt aaaaatacgc agaccattaa atatccaaag agattatcag
    21001 ggagttacat tgcaaatatg gcgcaaaaaa taacaccatc taaaattgtt aaacatgccc
    21061 gggagttaat tattaagggg attgaatcgg gcgaaaactc atttgtcatt tttgatgtag
    21121 atggagctct ggagcgtctg gatcattaca ggtgtcaact taagagtttt ttccccaaca
    21181 gtagtatcgc atattcatat aagtcaaata atctggcaca atggtgccag attatctcag
    21241 gtaaaggttt gtatgcagag gtgtgctctg ttgatgaaat gaacctcgcc aaaagagacg
    21301 gttttaagcg gattgttttt gatggccctt taaaaaaaac gagtgaacta ttaaaggcaa
    21361 tagagattgg ggcattaatt gaagttgaca atattgatga atgtaaaaga cttaatgaac
    21421 tatgtaagtt gcataagctg acatgtagaa ttcatttgag attatcgcat tactatgatg
    21481 ataatttatc aagatttggc ttatctgaaa gtgaggctat taatttactg gagatgttga
    21541 tcagtaagtc agagtatctc attttagacg ggttccattt acatgttggc tctaatctac
    21601 ccaatgcgga aaaaatatgt aaagctatta tacagtatca tgagttgatt cttaggtata
    21661 tgccagatga tggcactctt aatcttggta gtgggatacc tgcagattct ttctcagcat
    21721 ccagtgataa cccaactcca tgtccggagg tatttttctc atcgatatat gatacaataa
    21781 aaaattgctt cggtactgta tgtgataaat ggaactatat ttttgaacca gggagacatc
    21841 tggtcgaaga ctttggctac tttataggga aagttattag tactaaaaac aggtatggtg
    21901 ttaaagttgc tcaaactaac attggtataa actggatacc ttcgatcaga aattgggacc
    21961 attcatttac attgtttcat aatcataacc atatttcaga tgataaatct gatgagtata
    22021 ttattgctgg attcaattgc tttgaatgtg attgcttgtt tccttcagtt attcttccca
    22081 gtaacttatc tgattattta ttttctgttc gagggtgtgg tgcttatgat atgcaaacag
    22141 gaaaccagtg gacgcgtaat ctttatgctg tatataccat aacaaatgat gttgttaata
    22201 tatcaaggat tcacagaaga gaacttgatt tccggaagta tgatgtatct cttacgccat
    22261 caggaataaa agtaaatgat gaaattacat tattgtatcc agcgttaaaa tacgctgaag
    22321 agttatattt gctcattaat caaaacaaaa taaatttcat taaaagcatg gcatggccag
    22381 cgtttgttaa taacatttct gattctgttt ctttcattga gcaatcaatg attgataacc
    22441 agaatgaaaa agcattaatc ctctttatta aatacaaaac taagatagct ggcgttgtat
    22501 cgtttaatat tattgaccat gccaataaaa cagcatatat tggctattgg ttaggtgcta
    22561 actttcaggg gaaggggatt gtaaccaatg ctataaataa actgatacag gagtatgggg
    22621 attcgggcgt tataaaaaga tttgttataa aatgtattgt tgataataaa aaaagtaatg
    22681 ccacggcatt gaggtgtggc ttcaccttag aaggtgttct gcaaaaagca gaaatactca
    22741 acggtgtatc atacgatcaa aatatttatt caaaagtaat tggttaatac tgtatggcgt
    22801 agtattctac gccattttgt ttatgtctgt gagatgataa tatttatttc tcggtagata
    22861 gatattgttc tgttatagat atatttttgt tgtcaaagtc aatagctaat tttacaccaa
    22921 gtggaagagt tagcattgga tgtgtatgtg aacaatcaaa tccatccagt acaggaatct
    22981 gtttcccatc taatacctct gttaatactt catatggtct gcgtttactt cctgcacaat
    23041 caaaaagctc atgtttcccg agtattattg cactaacttt atcaaacacg cgattaagct
    23101 ttagcataga gaataatcgt tcaattgttg caatgctttt ccgactgtcc tcaataaaca
    23161 atatatctcc attaagaatt tcaggcatcc attcactccc ccatatacct gtcaaagtat
    23221 ttagatttcc tccaattaca cgcccctcaa cttttccgga accataaaag gcacagttgt
    23281 ttttatatag cttcttaggc cttaatatct tgttttcatt ccagtttatg ctctcatcac
    23341 tccacttttc aggtaatgtg taggtatata ttcctgattg ttttcttgtt agtattttaa
    23401 taaatgattc atatgttata tccacaagag gtggatgttc accaaacgaa ggaataagag
    23461 ctggtccata gaatgttatt aaccctgttt ttgcatatat tcctgctaat aaagcagttg
    23521 tatctgagta acctatgata attttggggt ttgcaatgat agcatcatag tccagaaacg
    23581 gtagtagtga attactgtta tctccaccga tcgttgacat tatacaggta atatcaggat
    23641 tgtagactaa ctcattaaat tcttgagctc tttctttaat agtacctgaa cgataaaaat
    23701 ctgttttacc ggtaagcttc cctgatacca gcttaaatcc ctttctctga agaaactcaa
    23761 ctccccgaaa aaaacgattt tttgcagtaa ctgttgccgg agcagatgat gaaaagaaac
    23821 caattgtatc tcctactgcc aggggagcgg ccagtagtgg atgagattgt atcatcatga
    23881 ggatttttcc tttccattta gtgtcaaaat gaacccgttt tgagatatgt cagtagcact
    23941 ttcagtttat gggctttttt tgaaaatcgc agtgttctct cgtaaatttt ctcgtccaat
    24001 cccccccgaa aagcctcaga tttcacgtag cgcaccgcca ctactgtatc catcaaaaaa
    24061 actgatagct tttttaatca tctgttgtgc tgcaacttac tgaaaaaaat ggattcatga
    24121 aaacgccgat aacggtattg atctgttggc caacgcgatc agcagtattg gtcgcaacaa
    24181 aaaat
//
