LOCUS       NZ_CP080558            19845 bp    DNA     circular CON 14-SEP-2023
DEFINITION  Staphylococcus aureus strain HL17078 plasmid pHL17078_2, complete
            sequence.
ACCESSION   NZ_CP080558
VERSION     NZ_CP080558.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN17301232
            Assembly: GCF_019551175.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 19845)
  AUTHORS   Kim,J.-M., Chung,S.H. and Kim,J.-S.
  TITLE     Whole genome sequence of MRSA HL17078
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 19845)
  AUTHORS   Kim,J.-M., Chung,S.H. and Kim,J.-S.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-JUL-2021) Laboratory Medicine, Hallym University
            College of Medicine, 150 Seongan-ro, Gangdong-gu, Seoul 05355, South
            Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 13-APR-2020
            Assembly Method                   :: SPAdes v. 3.14.0
            Assembly Name                     :: HL17078
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 515x
            Sequencing Technology :: Oxford Nanopore MinION; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 09/14/2023 05:34:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,034
            CDSs (total)                      :: 2,952
            Genes (coding)                    :: 2,866
            CDSs (with protein)               :: 2,866
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 47 of 86
            Pseudo Genes (incomplete)         :: 43 of 86
            Pseudo Genes (internal stop)      :: 14 of 86
            Pseudo Genes (multiple problems)  :: 17 of 86
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP080558.1.
            Annotation performed at Hallym University College of Medicine on
            July 30, 2021 using the NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP) version 2021-01-11.build5132.  Annotation modified by
            submitter.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..19845
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="HL17078"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pHL17078_2"
                     /geo_loc_name="South Korea:Seoul"
                     /lat_lon="37.5362 N 127.1356 E"
                     /collection_date="2015"
                     /collected_by="Kandong Sacred Hospital"
     gene            1..618
                     /gene="cadD"
                     /locus_tag="JMO10_RS15005"
                     /old_locus_tag="JMO10_003002"
     ARG             2..615
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            637..984
                     /locus_tag="JMO10_RS15010"
                     /old_locus_tag="JMO10_003003"
     CDS             637..984
                     /locus_tag="JMO10_RS15010"
                     /old_locus_tag="JMO10_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            1141..1233
                     /locus_tag="JMO10_RS15015"
                     /old_locus_tag="JMO10_003004"
     CDS             1141..1233
                     /locus_tag="JMO10_RS15015"
                     /old_locus_tag="JMO10_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(1405..2376)
                     /locus_tag="JMO10_RS15020"
                     /old_locus_tag="JMO10_003005"
     CDS             complement(1405..2376)
                     /locus_tag="JMO10_RS15020"
                     /old_locus_tag="JMO10_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_000481279.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            2500..2919
                     /locus_tag="JMO10_RS15025"
                     /old_locus_tag="JMO10_003006"
     CDS             2500..2919
                     /locus_tag="JMO10_RS15025"
                     /old_locus_tag="JMO10_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            complement(3445..4290)
                     /gene="blaZ"
                     /locus_tag="JMO10_RS15030"
                     /old_locus_tag="JMO10_003007"
     ARG             complement(3449..4290)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            4397..6154
                     /gene="blaR1"
                     /locus_tag="JMO10_RS15035"
                     /old_locus_tag="JMO10_003008"
     ARG             4398..6151
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            6144..6524
                     /gene="blaI"
                     /locus_tag="JMO10_RS15040"
                     /old_locus_tag="JMO10_003009"
     ARG             6145..6521
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            6788..7366
                     /locus_tag="JMO10_RS15045"
                     /old_locus_tag="JMO10_003010"
     CDS             6788..7366
                     /locus_tag="JMO10_RS15045"
                     /old_locus_tag="JMO10_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690637.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(7589..7774)
                     /locus_tag="JMO10_RS15050"
                     /old_locus_tag="JMO10_003011"
     CDS             complement(7589..7774)
                     /locus_tag="JMO10_RS15050"
                     /old_locus_tag="JMO10_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001037130.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            8036..8710
                     /locus_tag="JMO10_RS15055"
                     /old_locus_tag="JMO10_003012"
     CDS             8036..8710
                     /locus_tag="JMO10_RS15055"
                     /old_locus_tag="JMO10_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105991.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(8752..9378)
                     /locus_tag="JMO10_RS15060"
                     /old_locus_tag="JMO10_003013"
     CDS             complement(8752..9378)
                     /locus_tag="JMO10_RS15060"
                     /old_locus_tag="JMO10_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_220375437.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNGSVAK"
                     /name="IS6 family transposase"
     gene            9852..11318
                     /gene="msr(A)"
                     /locus_tag="JMO10_RS15065"
                     /old_locus_tag="JMO10_003014"
     ARG             9853..11315
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            11417..12316
                     /locus_tag="JMO10_RS15070"
                     /old_locus_tag="JMO10_003015"
     CDS             11417..12316
                     /locus_tag="JMO10_RS15070"
                     /old_locus_tag="JMO10_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000196697.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            12802..13410
                     /locus_tag="JMO10_RS15075"
                     /old_locus_tag="JMO10_003016"
     CDS             12802..13410
                     /locus_tag="JMO10_RS15075"
                     /old_locus_tag="JMO10_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583528.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            13656..13994
                     /locus_tag="JMO10_RS15080"
                     /old_locus_tag="JMO10_003017"
     CDS             13656..13994
                     /locus_tag="JMO10_RS15080"
                     /old_locus_tag="JMO10_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001049146.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            13999..14184
                     /locus_tag="JMO10_RS15085"
                     /old_locus_tag="JMO10_003018"
     CDS             13999..14184
                     /locus_tag="JMO10_RS15085"
                     /old_locus_tag="JMO10_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000797248.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(14411..15154)
                     /locus_tag="JMO10_RS15090"
                     /old_locus_tag="JMO10_003019"
     CDS             complement(14411..15154)
                     /locus_tag="JMO10_RS15090"
                     /old_locus_tag="JMO10_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            15580..16563
                     /locus_tag="JMO10_RS15095"
                     /old_locus_tag="JMO10_003020"
     CDS             15580..16563
                     /locus_tag="JMO10_RS15095"
                     /old_locus_tag="JMO10_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001181107.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            <16583..16873
                     /locus_tag="JMO10_RS15100"
                     /old_locus_tag="JMO10_003021"
                     /pseudo=""
     CDS             <16583..16873
                     /locus_tag="JMO10_RS15100"
                     /old_locus_tag="JMO10_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            17417..17566
                     /locus_tag="JMO10_RS15105"
                     /old_locus_tag="JMO10_003022"
     CDS             17417..17566
                     /locus_tag="JMO10_RS15105"
                     /old_locus_tag="JMO10_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000695366.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(17734..18426)
                     /locus_tag="JMO10_RS15110"
                     /old_locus_tag="JMO10_003023"
     CDS             complement(17734..18426)
                     /locus_tag="JMO10_RS15110"
                     /old_locus_tag="JMO10_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            18536..18730
                     /locus_tag="JMO10_RS15115"
                     /old_locus_tag="JMO10_003024"
     CDS             18536..18730
                     /locus_tag="JMO10_RS15115"
                     /old_locus_tag="JMO10_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     ARG             11418..12313
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             9853..11318
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             11418..12316
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             complement(3446..4290)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     Typing          16932..17076
                     /name="MOB_unknown"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="96.575"
                     /coverage="88.0"
                     /evalue="6.92e-62"
     Typing          complement(14412..15154)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          15581..16563
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          16695..16865
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="94.186"
                     /coverage="91.0"
                     /evalue="6.2e-68"
ORIGIN
        1 atgattcaaa cggttgttgc tgctgctgtt ctttatattg ctacagcagt tgatttatta
       61 gtaattttat taatattttt tgctagagca aagactagaa aagaatatag agatatttat
      121 gttggtcaat atttagggtc tattatttta atattagtta gtttgttttt agcttttgta
      181 ttaaattatg ttccagaaaa gtggatatta ggtttattgg gtttaatacc aatttatctt
      241 ggaattaaag tggctattta tgatgattgt gaaggagaaa agagagctaa aaaagaattg
      301 aatgaaaaag gattgtctaa attagttggt acggttgcaa ttgttacgat agcaagttgt
      361 ggcgccgata atattggttt atttgttccg tattttgtga cattaagtgt tactaattta
      421 ttacttactc tgtttgtctt tttaatttta attttcttct tggtgtttac tgcacaaaaa
      481 ttagctaata ttccaggaat tggagaaatt gttgagaaat ttagtcgttg gattatggct
      541 attatttata tagctttagg tttatttatt attattgaaa atgacactat tcaaacaatt
      601 ttaggattta tattttaatt tagggtgtga ttttatatga gttatgaaaa tacttgtgat
      661 gtgatctgtg tacatgagga taaagttaac aatgctttaa gttttttaga agatgataaa
      721 tctaagaaat tacttaacat tttagaaaaa atttgtgatg agaagaaatt gaaaatcata
      781 ttatctttga ttaaagaaga tgagttgtgt gtttgtgata tttctttgat attgaaaatg
      841 agtgttgctt caacttcaca tcatttaagg cttttatata aaaatgaggt acttgatttt
      901 tataaagatg gaaagatggc atattatttt attaaagacg atgaaataag agagtttttc
      961 tctaaaaatc atgagggttt ttgaaacgag tttcttcttg tcttgatact ataaaaaaca
     1021 aagttatata acataagacg acttatcgga agtagatatg cttgtatatt cacagatggt
     1081 ataataatag agtcgcctat ctctcaggcg tcaattgacg aagagaggag gtgcattact
     1141 ttgctaatca ttttcgttca catcatagca ccagtcatca gtggctgtgc tgttgcgtat
     1201 tatacttatt ggcttagtaa acgcaacaaa taattaatag gcgactttat aagccagcat
     1261 cgaaaaaatc cccacactac tgcaatagtg tggggattgg tgcattaatt gttaatcatt
     1321 ttcgttatat aaattataac actggttagt agagaaatgc aaaatgattg aattaatagt
     1381 aaatgtatta atgaatactc acacttatac ttttaaaata gttcttccta aatgttgtcc
     1441 ttttaaaagc tgatctatcg ttttatagaa ttcttcaaat ccaatttcat tgtatagaag
     1501 tgaatttcct atattccatt catttgctaa cttactccat atatcttcac ggatattatg
     1561 atcaacatat acagaatcaa tgccaattaa tttaatacct ctaagaataa acggtaatat
     1621 attagcgtta agtgaatttc ctgctacatt tccacataca gtagcaacac cttgataatt
     1681 tagacgtttt aaaccgtata atgttacatt actccccact gtatctaaga aataatcaaa
     1741 aatacctttt ttaagcggtt tattatcatc ttcaattatt attacttgtt ttgcacctaa
     1801 tttttttgcg atttctattt gcttttcttt tcttacgata gcagtgatat tttcatatcc
     1861 aattttatgt aaaatttgta tagcaacact gcccacacca cctgtagccc cagacactaa
     1921 aatttcaggt tgtgatttga tattcattcc atatttttct agttcaaaaa ttgataatgc
     1981 tgccgtaaaa ccggctgtgc catataccat agactcttta atagacattt cttggggaat
     2041 aggaacaatc cactctccag gcacttgtgc atattctgaa aatccacctg tatgtgtcac
     2101 gccaacatca taaccagtaa ctaatacatt atcgccttct ttaaacttat cattcgaact
     2161 tgattcaaca atacctgcaa aatctatacc aggaatcata ggataatctc taattacacc
     2221 gcctttatat tgtaaagcta gcatatcctt ataatttatt gaagagtata ccacttttac
     2281 taatacatca cccttcgata aatgagattc atcaactttt tctactttat aactaacatt
     2341 tgatgcactt tttctcacta ctaccgcatt gaacatttat tagccttctt tcacaattgt
     2401 tttgtagaag tatgtttttg ttgcaaaact attttcctac aaaacttatc atgatatgat
     2461 aagcgagtca atactaatga tttaagagag gttttagttg tggaattaga taattgtata
     2521 aattatttgt tgagtacttc tcagaataga gtttttaaac attttaaaag tttattaagt
     2581 ccctataata ttactccagc agaatatggt gttttgaatt gcttgattaa tagtaatttg
     2641 aatacaccta aagcgattgg taatacttta aatttagaac cttcaacaat atctggaata
     2701 ttagataaga tgtccaaaaa ggatctaata acacgtcaaa ctgataatga aaatagaaga
     2761 actgtgctaa taaacagtac aaataaagca aaagacttat ggccaacatt agaaaagaaa
     2821 gcctatcaac ttaataatca ttacttcgct aatttaacta atgaagaaac tgtagtgttt
     2881 aaaaagatat tactaaagat aaataaaact acgttttaat ttttacgtta taaaaaagtt
     2941 gaagtgcgaa ttataatcga gtaaatataa atgatagctt agcttaatta tatattaaag
     3001 ccaactatac ttttattccc gaaaaaccta ctatccaaat ttctaagata ctttagcctc
     3061 tataataaac atattgtaat ataatttatg tattatttag gtttacccta atcgaacaat
     3121 aaaaaatact tgtaaaatgc tattgtcact ttgcttgata tatgagaatt atttaacctt
     3181 ataaatgaga aaaaagcaac gcactttaaa taagatacgt tgctttttcg attgatgaac
     3241 acctataatt aaactattca tctattattt atgatttttt gtatatacaa tatttctagt
     3301 ttgttaaaga gaattaagaa aataaatctc gaaaataata aagggaaaat cagtttttga
     3361 tatcaaaatt atacatgtca acgataatac aaaatataat acaaactata agatgttatc
     3421 agtatttatt atgcatttag aatattaaaa ttccttcatt acactcttgg cggtttcact
     3481 tatcaactta tcatttggct tatcactttt attgtcttta ttcgtaaaaa tgactaaaac
     3541 aataggttca gattggccct taggataaac aaaagcaaca tcatttctag aagcatatgt
     3601 tattgcttga ccacttttat cagcaacctt atagtctttt ggaacaccat ctttaattaa
     3661 agtgtctccg tttttattat taaacattaa atcaagtaag aaatttttat tttttttgct
     3721 taattttcca tttgcgataa gtttatttaa agtcttgccg aaagcagcag gcgttgaagt
     3781 atcttttttg ctctttggtg aatagtaatt taattctatc tcatatctaa ctggatttgt
     3841 tactttatct cctagttctt ttagacgttg tttaactttt ttgattccac cgatttcttt
     3901 tataatttta ttgtttgctg tattatcact atatgtcatt gaagcctcaa taagttcttt
     3961 taaagtgata tcttttccta catatttttc taaaatagga gaataagcaa ctatatcatc
     4021 tttgttaata tgtacttttt tatttaactt attataaggt acttgttcta acaaaatagc
     4081 actatttatc gcttttgaag tcgaagcata ggcaaatctc ttatctgaat taaattttac
     4141 ttccttacca cttttagtat ttaaagcata aacaccaata tgagcattat attttttttc
     4201 taaatcattt aactctttgg catgtgaact gtttgaatta catgcactta aaactaaagc
     4261 aattacaatt aaaaatatta actttttcaa aataaaccct ccgatattac agttgtaatt
     4321 tttataaatc aataatatta caattgtaat attgatgtca attgtttatt ataaatattt
     4381 gaaagaaggt gtcaaaatgg ctaaattact aataatgagc gtagtaagct tttgttttat
     4441 atttctattg ttagtatttt ttaggtacat attaaaacgc tattttaatt atagtttaaa
     4501 ttataaagtt tggtatctaa ctatgcttgc tggattaatt ccttttatcc caattaaatt
     4561 ctcttttata aaatttaata atgtgaataa tcaagcgccc acagttgaaa gtaagtcaca
     4621 cgatttgaac cataacataa ataccaccaa acctattcaa gagttcacaa cagatatcca
     4681 taagtttaat tgggattcaa ttgataatat ctgcacagtt atttggatag ttttagttat
     4741 tattttaagt tttaaatttt tgaaagcctt attatatctt aaatatttaa agaaacagtc
     4801 actttatcta aacgaaaatg aaaaaaataa aatagatacg atacttttca accatcaata
     4861 taaaaaaaat attgtgattc gaaaagcaga ggctattcaa tctccaataa ctttttggta
     4921 tgggaaatat attattttga ttcctagttc atattttaaa agtgtaattg ataaaagact
     4981 aaaatatata atactgcatg aatatgctca tgctaaaaat agagatactt tacatttaat
     5041 tatctttaat atcttctcta ttattatgag ttacaatcca ttagtacata ttgtaaaaag
     5101 aaagataatt catgacaatg aagtagaagc cgatagattt gtccttaata atattaacaa
     5161 aaatgaattt aaaacttatg cggaatctat tatggactcc gtattaaaaa ccccattttc
     5221 caacaaaaat atattaagcc attcatttaa tggtaaaaaa tcattactca aaagtagatt
     5281 aattaatata aaagaagccg atctgaaaaa gcagtcaaaa ttaattctaa tttttatttg
     5341 tatttttact ttttttatca tgataattca aagccagttt ttaatggggc aatccttaac
     5401 tgattataat tataaaaagc ccttacaaag cgattaccaa attttagatg aaagtaaaaa
     5461 ttttggttca aatagtggat ctttcgttat gtacagcatg aagaaagaca aatactatat
     5521 ttataatgaa aaagaaagta gaaaaagata ttctcctgat tcaacttaca aaatttattt
     5581 agcactgttt ggacttgacc gtcatattat aagtgataaa aattcacgta tgtcatggaa
     5641 tcataaacat tatcttttcg agtcttggaa taaggaacaa gatttaaata cagcaatgca
     5701 aaattcagtt aattggtact tcgaacgtat tagtaatcaa ataccaaaga actatactgc
     5761 ggctcaactc aagcaattaa attatggtaa tgaaaatttg ggaagttata aaagctattg
     5821 gatggaagat agtttgaaaa tatctaatct tgaacaagta atagttttta aaaatatgat
     5881 ggaacaaaat aaccatttta gtaaaaaagc aaagaatcaa ttatcttctt cattattgat
     5941 taagaaaaat gaaaagtatg aactgtatgg gaaaacaggt acaggtatag taaacgggaa
     6001 gtataataat gggtggtttg taggttacgt aattacaaat catgataagt attattttgc
     6061 tacacattta tcagatggaa acccgtctgg gaaaaatgct gaattaataa gtgaaaaaat
     6121 attaaaagga atgggtgttt taaatgacca ataagcaagt tgaaatatct atggctgaat
     6181 gggatgttat gaatataata tgggataaaa aatcagtatc agctaatgaa attgtagttg
     6241 aaattcaaaa atataaagaa gttagtgata aaacgattag aacattaatc acaagactat
     6301 ataaaaaaga gattataaaa cgatacaaat cagaaaatat ttatttttac tcatcaaata
     6361 ttaaagaaga cgatattaaa atgaaaactg ctaaaacctt tcttaataaa ctgtatggag
     6421 gggatatgaa aagtttagtg ctgaattttg cgaaaaatga agaattaaat aacaaagaaa
     6481 ttgaagaatt gcgagacatt ttaaatgata ttagtaaaaa gtaattagag gtatgtttca
     6541 aacataatac atatgtaaac catacttgac tcttattaaa ttagttttgt taatgacatt
     6601 taaaatatat tattaaagat gagagtgtcc agaaaataac cattttctgt acactcttgt
     6661 tttttgtcta aataagtaag tattacatag aattatgtgt tcaaaaaccc aacaaaaaat
     6721 ctatgttcac aaaagacctc gtaatcaagt tatggtacac taaaggtgta tataggaggt
     6781 ctgtattttg aaaataggtt atgcaagagt ttcaactgga ttacaaaatt tgaatttaca
     6841 ggaggatcga ttaaatacat atggttgtga aaagatattt aatgaccata tgagtggttc
     6901 aaaaagtaag cgacctggtt tagataaagc aattgaattt gcgaggtcag gagatacgat
     6961 tgttgtttgg agattagata gactaggacg gaacatggag gatttaatca cgttagttaa
     7021 tgaacttaac gaacgaggtg tgagttttca tagtttagaa gaaaatataa cgatggataa
     7081 atcaagttct acaggacaat tattatttca tttattcgca gcatttgcag agtttgaacg
     7141 taatttaatt ttagagcgat catcagccgg tcgaattgca gcacgtgcta gaggccgata
     7201 tggaggtaga cctgaaaaat taaataaaca agatttaaac ttacttaaga cactttatga
     7261 taatggtacg ccaattaaaa caattgcaga gcagtggcaa gtttcacgta caactattta
     7321 tcgttatctc aataaattag aggcaaaaga gaataaaaac aagtagagca actaatctag
     7381 cttactataa tgaatctact aaataatttt atatatcatt aacatacaaa gactttgatt
     7441 caatgtcact cgatgtaaaa gagacgttct gacagcgtct aaaatctcat aatattttcc
     7501 tgttatgaga ttttaataat aacacaagaa aaaagcgtac aaattcgtac gcttttttaa
     7561 tataatacct gtttcactaa tgaacgtttt aagtatcttc atcattaact gaaactacag
     7621 taataatact cgtcaacaat attagtatag ttaaaataga aagacttagg actggcataa
     7681 ccgaactaaa attatatttg aaatataaaa gtgctaatga agagagaaat gtaaaaataa
     7741 taaataccaa agaccatttt tctaatttat tcattggctt cacctctttg aacttttata
     7801 taatcatagg agatattttt actacgattt ataaaaaata agaagataat cattattaaa
     7861 gaaacgatta atataatgtt gaatcctata gtatcaccta attcgtttac acctttgcct
     7921 aatatcggag atacaaagct ttgtattaat aatgaaagag atgcccatat agtaaatgag
     7981 gttctgttgc aaagttgaat ttatagtata attttaacaa aaaggagtct tctgtatgaa
     8041 ctatttcaga tataaacaat ttaacaagga tgttatcact gtagctgttg gctactatct
     8101 aagatatgca ttgagttatc gtgatatatc tgaaatatta agggaacgtg gtgtaaacgt
     8161 tcatcattca acggtctacc gttgggttca agaatatgcc ccaattttat atcaaatttg
     8221 gaagaaaaag cataaaaaag cttattacaa atggcgtatt gatgagacgt acatcaaaat
     8281 aaaaggaaaa tggagctatt tatatcgtgc cattgatgca gagggacata cattagatat
     8341 ttggttgcgt aagcaacgag ataatcattc agcatatgcg tttatcaaac gtctcattaa
     8401 acaatttggt aaacctcaaa aggtaattac agatcaggca ccttcaacga aggtagcaat
     8461 ggttaaagta attaaagctt ttaaacttaa acctgactgc cattgtacat cgaaatatct
     8521 gaataacctc attgagcaag atcaccgtca tattaaagta agaaagacaa ggtatcaaag
     8581 tatcaataca gcaaagaata ctttaaaagg tattgagtgt atttacgctc tatataaaaa
     8641 gaaccgcagg tctcttcaga tctacggatt ttcgccatgc cacgaaatta gcatcatgct
     8701 agcaagttaa gcgaacactg acatgataaa ttagtggtta gctatatttt tttactttgc
     8761 aacagaaccg ttctttttat atagagcgta aatacactca atacctttta aagtattctt
     8821 tgccgtattg atactttgat atcttgtctt tcttacttta atatgacggt gatcttgctc
     8881 aatgaggtta ttcagatatt tcgatgtaca atgacagtca ggtttaagtt taaaagcttt
     8941 aattatttta gccattgctg ccttcgttga aggtgcctga tctgtaacta ccttttgagg
     9001 cttaccaaat tgtttaatga gacgtttgat aaacgcatat gctgaatgat tatctcgttg
     9061 cttacgcaac caaatatcta atgtatgtcc ctctgtatca atggcacgat ataaatagct
     9121 ccattttcct tttattttga tatacgtctc atcaatacgc catttgtaat aagctttttt
     9181 atgctttttc ttccaaattt gatataaaat tggggcatat tcttgaaccc aacggtagat
     9241 cgttgaatga tgaacgttta caccacgttc tcttaatatt tcagatatat cacgatagct
     9301 caatgcatat cttagatagt agccaacggc tacagtgata acatccttgt taaattgttt
     9361 atatctgaaa tagttcatac agaagactcc tttttgttaa aattatatta taaattcaac
     9421 tttgcaacag aaccgtattt tatgagtaca ctctaaatta aggagatgta taatcaatct
     9481 aaaattgtat ttttatactt tcgttatata atctttctac ttagagatat attgtaaaaa
     9541 aaccaacaaa atgttatatt aacattacta ttttatcgat gaaggaggat taaaatgaca
     9601 gcttctatga gactcaaata aacctttttg aatacaaaac taaattaatt caaaaaggct
     9661 tgtccgcaat acacactcat aggatgactt atgtcatttt ttatccttcg ataggaataa
     9721 taaacgcttt caaatactaa aacatcataa taaattttta agtgtttgaa agtgtaatgt
     9781 gaatgagacg ggagtagcct gtctcatttt tttgcgtaca cgtcctttaa atatacaagg
     9841 agtgtataaa tatggaacaa tatacaatta aatttaacca aatcaatcat aaattgacag
     9901 atttacgatc acttaacatc ggtcatcttt acgcttacca atttgaaaaa atagcactta
     9961 ttgggggtaa tggtactggc aaaaccacat tactaaatat gattgctcaa aaaacaaaac
    10021 cagaatctgg aacagttgaa acggttggcg aaattcaata ttttgaacag cttaacatgg
    10081 atgtggaaaa tgattttaac acgttagacg gtagtttaat gagtgaactc catataccta
    10141 tgcatacaac cgacagtatg agtggtggtg aaaaagcaaa atataaatta gctaatgtca
    10201 tatcaaatta tagtccgata ttacttttag atgaacctac aaatcacttg gataaaattg
    10261 gtaaagatta tctgaaaaat attttaaaat attactatgg tactttaatt atagtaagtc
    10321 atgatagagc acttatagac caaattgctg acacaatttg ggatatacaa gaagatggca
    10381 caataagagt gtttaaaggt aattacacac agtatcaaaa tcaatatgaa caagaacagt
    10441 tagaacaaca acgtcaatat gaacagtata taagtgaaaa acaaagattg tcccaagcca
    10501 gtaaagctaa acgaaatcaa gcgcaacaaa tggcacaagc atcatcaaaa caaaaaaaca
    10561 aaagtatagc accagatcgt ttaagtgcat caaaacaaaa aggcacggtt gagaaggctg
    10621 ctcaaaaaca agctaagcat attgaaaaaa gaatggaaca tttggaagaa gttgaaaaac
    10681 cacaaagtta tcatgaattc aatttcccac aaaataaaat ttatgatatc cataataatt
    10741 atccaatcat tgcacaaaat ctaacattgg ttaaaggaag tcaaaaactg ctaacacaag
    10801 tacgattcca aataccatat ggcaaaaata tagcgctcgt aggtgcaaat ggtgtaggta
    10861 agacaacttt acttgaagct atttaccacc aaatagaggg aattgattgt tctcctaaag
    10921 tgcaaatggc atactatcgt caacttgctt atgaagacat gcgtgacgtt tcattattgc
    10981 aatatttaat ggatgaaacg gattcatcag aatcattcag tagagctatt ttaaataact
    11041 tgggtttaaa tgaagcactt gatcgttctt gtaatgtttt gagtggtggg gaaagaacga
    11101 aattatcgtt agcagtatta ttttcaacga aagcgaatat gttaattttg gatgaaccaa
    11161 ctaatttttt agatattaaa acattagaag cattagaaat gtttatgaat aaatatcctg
    11221 gaatcatttt gtttacatca catgatacaa ggtttgttaa acatgtatca gataaaaaat
    11281 gggaattaac aggacaatct cttcatgata taacttaaaa actatacact aatttatatt
    11341 gaatattagg ttcatttata tcaatataaa aaatacgttc acaagaaaaa tataatagaa
    11401 ataaggatcc aataaaatga ctcgacataa tgaaattatt aaatgtgcag aaaaatatca
    11461 attacacatc caacctcaaa caatctcatt gaatgaatcg ggacttgatt ttcaagttgc
    11521 atttggaaaa gataaacatg gagtagaatg ggttttgaga ctaccaagaa gacctgacgt
    11581 ttataaacga acaaaacccg aaaaacaaac ggtagacttc ttacagaaga atgtttcatt
    11641 tgaaataccg aagtggaaag tacatgcaaa agaccttatt gcttacccaa aacttacagg
    11701 taaacccgca gccacaatag atccagaaat acaaaattat gtatgggaaa ttgaacacaa
    11761 accattacca gaaaacttta ttaacacatt agctgaaaca ctcgtagatt tacacaacat
    11821 accagaagaa aacattaacg ttcagcatat aaatatcaaa accatacaag aaataaaaaa
    11881 tgactttcaa agaagaatga ataaagttaa agaaacttat ggcgtatcag atgaattatg
    11941 gaacagatgg aaacaatggt tagaaaacga cgaactatgg cctcgacatg cgaccatgat
    12001 acatggggac ttacatccag gacatataat ggtagataac caagcaaacg tcacaggtct
    12061 catagactgg actgaagcaa cccactccga cccatcaatg gactttatag gacaccatcg
    12121 tgtattcgac gacgaaggat tagagcaact tataacagca tacggtaaag ctggaggtga
    12181 aatatggcca cgaatgaaag agcatataat agaactcaat gcagtattcc caatgtttat
    12241 cgctgagttt gctatggaat caggagaatc ggcgtatgaa acgatggcat tgaaagagtt
    12301 aggtatgaaa gagtagaact tatattaaaa gaggcccatt ttaaagacga aggcaatcct
    12361 gatgaaattt taaaactgcg tttaattagt gatggtcttt ggttttctat aatgtattaa
    12421 atatctggac atggaacaaa tgcaacaaat ggaaagaatc gttttcgaaa tttctaactc
    12481 cttaaatcag gaggataaat aaacggtcat tttcattgaa agcacttata taaatttcat
    12541 caattttaat acctaccgta aatacatttc ataagtatta aacagatgat taaaattttt
    12601 agttaattta aatatttatg atagagatga ccttcaaatg aacggttctg ttacaaagaa
    12661 aaaatctata tttattttta gtaagtttta attatagata tgtacacttt gagtacaccc
    12721 taaccataca aaaagaattg ttgaaattat aacaattaaa acgtatgatt agggtgtata
    12781 tttattatgg agtgaagatg aatgattata ggttatgcga gagtatcatc gatagatcaa
    12841 aatttagaaa gacaattgga taatttaaag acgtttggtg tggagaaaat ctttacagag
    12901 aaacagtcgg gaaagtcagt ggaaaataga cctgtatttc aagaagcact caattttgtc
    12961 agaatgggag atcgattcgt tgtggaatct attgatcgtt taggacgtaa ctatgatgaa
    13021 attattgaaa ctgtgaatta tttaaaagaa aaagacgttc agttaatgat taccagctta
    13081 cctatgatga atgaagtaat tggcaatcca ttactggata agtttatgaa agatttaatc
    13141 attcaaatat tagcaatggt ttcagaacaa gagagaaatg aaagtaaacg tcgacaagcg
    13201 caagggattc aagttgcgaa ggaaaaaggc gtatataaag ggcgcccttt actttattca
    13261 ccaaatgcta aagacccaca gaaacgtgtt atttatcatc gcgtggtgga aatgttagaa
    13321 gaaggcaaag cgattagtaa gattgcgaaa gaagttaata tcacaagaca aacagtttat
    13381 agaattaaac atgataaggg attatcttga taaattgatt gtcaatgcaa atgagcgtct
    13441 ctcacagtgt ctcaaattcc ataacatatt attgaattga gattttaata attatacaag
    13501 aaaaaagagt acgagttcgc agctttctat atagtaattg ttttactaat aaggtgtttt
    13561 aaaatatatt ataatgtaaa aagtatttga catttgtatc aaaaatattt acactcataa
    13621 atgtcaaata ctttttacat ttatgaggtg ttataatgaa tttaattcct tttattatta
    13681 ttttaatttt ttcttgttta tggacggcta taactaacaa atatttacct tcagaaacat
    13741 tagataaaaa aggacaacaa gatcgatacg atgaaagaca acgtaaaatg tttattgaaa
    13801 tactggctaa aagttttatt tggattgtat attgtatgtt atttacacta gtgcttaaat
    13861 ttacaggttt gtcaccaagt attgaaggat cttggttttc tcaatatcca gaaattttct
    13921 ttataattgt agcactattt cttatgctgt ttaattacta tactacaaat aaaaaatata
    13981 catctaaagg ttaaattaat gaaaaataga attagagaat atagaaaaca aaaaggaatt
    14041 tctcaagaaa ctttaagtaa agaattaaaa gtgtctaggc aaactattaa tgcaatagaa
    14101 aacaataaat atgatcctac attgacatta gcatttaagt tggcaagatt gtttgataca
    14161 actgtggatg aattattttc ttaaccattc atttatcaca aaaagagagt gcgaattcgc
    14221 actctctttt tgtgtagtag tactattaaa ttttgtctca ataacgaacg tttataacgc
    14281 aatcatgatg agagtattaa tacagttaat tatttgaaat actttagttt acataatcga
    14341 tgattaccag aagttctcac tatataaaag acactaaaat tttataactt ttagtgccta
    14401 atcaattatt ttagctacca aacaaacgac tccaaaaccc ctttttaggt tccgtttctt
    14461 cactcttttc ttctatatca ctatcattgt catttagatt agctggaacg tcttcttttt
    14521 ttgcttcttc accttgtgta ctttcgtcgc tttgacttcc agatatatcc ttatattgaa
    14581 tctctgtttc tttagtttct tcctgatctc tgttaatatt tacaggatta gtagtatatg
    14641 ttttttcttg tgcatcaacg ttttgtctag tgttagtaga tgtatcaaag ggataattaa
    14701 ggtgtttttc tttttctaat tgattttcta atttttgaat ctttttatta ctctctaatg
    14761 ccagaacttg ctgattttca agcaattttg atctttcttg caactctttt ctgtaaaatt
    14821 caattgttgt ttcatgacga ctttcttgtt tttcaatttg attatttaaa gtatcaatct
    14881 gatttttaag gatttctact atttgagcat cgcttttcga ttcaaaatta atattatccg
    14941 accctttttt ttgtttgtct tcagtagtac tttcaaaacc atatttcttt ttattttcat
    15001 ttactctttg aatgattttt tctatatcgg tatcttcttt aataaacgaa gtgttttcct
    15061 gttttattgt ctctatattc aatcgcttaa tattattaaa aatcgtttgc ttactaaccc
    15121 ctaattcttc actcaacttt ttcacacttt tcatatcatc aaccctttat aaaatgttta
    15181 taaacccttg ataaaatatt ataagcttat aatgcttaat aataaagtga ttaataaata
    15241 aaaataaaca tccatcaacc tttttatcaa gggtttatga aaggtttatg atatttatca
    15301 agggtttata aacccttgat aaagctatat tttccctttt ataagtttat ttaaagtgct
    15361 ataataaact taatataaca aaaaccccaa ctactggtaa tagtcggggt ttggtaataa
    15421 aacgtttaga aactgtttat ttatataatt ttcgatactt gtattatata atgaataata
    15481 tcttagtgca agcacctaaa tcattaaata aatgtaaagc taaataaaaa cgttttatta
    15541 cctcttacca aactaaaata tggaaagagg ttttttgtca tgcaaaatca atattttaca
    15601 gtgcaagaaa attacaaaga aagattttat caaatcccta aagtattctt taccagtgaa
    15661 aattataaaa atctaactaa tgatatgaaa atagcctatg ctatcttacg tgatcgctta
    15721 aatttatcta ttaaaaatag ctgggttgat gaagatggta acatttactt tgtttattca
    15781 aatgaaaagc taatggaaat cttaaattgt aaaaaagaaa agttaacaaa aataaaaaaa
    15841 gggttagaaa acgatggtct actcattcaa aaacgacgtg gtttaaataa accaaatatt
    15901 ctatatttaa tgaaacctat tgtcacagaa cgtgatattt acaaaataga aaaagaagaa
    15961 aacgatgttg aaccttacgg cgagaaggaa gttcgaaaat cgaacgtcca gaagttcgaa
    16021 aatcgaacgt ccagaagttc gaaaatcgaa cgtccagaag ttcgaaaatc gaacactaat
    16081 gatactgact ttaatgacat tgactttaat gatactgaga ataatgatat gaatgacttg
    16141 aatgatataa agtacaaaaa tgaaattagt aatcattcaa atcattcaaa tcaatttaca
    16201 cataattttg atgataaaga aatgctattg caagaattcc cagaacaact aactaattat
    16261 ttattaaaat atgattatag agatttagaa atcataaagg ctgttattct taaagcaaaa
    16321 aaatcattta attcaaggca tgaagatatg cattacatgt tagaggacat tgaggatgaa
    16381 atattaactt ctttaaaaag acttaaaaaa gctatacatg ataggggagt taaaggccaa
    16441 aaggaaacaa tcaagtcaat gcaagcttat ttaatgcaaa caattctaac tgaacttgaa
    16501 gaaacacatg ccctttatat gcgccgtaaa aacatgaaac aatataatat ctttaatcaa
    16561 taattcaaat gattttataa cactcgaaga gacctcaaaa tattcggtta aatcatctga
    16621 ttttttaact gatgatgatg aaaaaaatca agaaattgta agtgatttag aaaaaggttt
    16681 gtatcgaaaa cgtatgttaa gttatggtgg attgcttaaa caaaaacata aaattttaaa
    16741 cttagacgat gtcgaagatg gtaatttgat taatgcaagt gatgaagata aaacaacaga
    16801 cgaagaagaa aaagcacatt caattaccgc aatttggaat ttcgaaaagc aaaattatta
    16861 tttaagacat tagtgttgac taatgtcttt tttgttgatt ttttataaaa aagtactgtc
    16921 ttatttttgt gacaaatgct gtatgtagtg tcacaaaaat aagacagtac agctttgtat
    16981 gatatcactt taaaatacct taaaacccct ggaatttctg gctttgccag acctatcatt
    17041 tttgaatgat agcaaattct ccttatgctc ttacggagtt tttagagaaa aattaaaaat
    17101 tctcgatttt tgataaaaaa cgccctgcag gaatttagaa aaacatgtgg aagttttaaa
    17161 ggattttatg ctaattttta atttgcatgt aaatgggcag tgttaaaaaa ttagtcactg
    17221 gttttgctga aatttttgtt tgtgaaatta ccatatattt atttggctca tatttgcgtt
    17281 ttaagagctt gtatatattt ttaagttaaa aacctatatg atttgcctct aagtcttcaa
    17341 aatgcctctt aaaatccaaa ataaaagtgt ttaatattgt aataaggatt gctattttta
    17401 taaaaggaga gatatcatga agattaaaac tttcgctact tttactcatc gtcaattaga
    17461 taaacaagtt aataggtttt taaagaatga tattcatgta ttagaaattc aaacacacag
    17521 taattggtta tatatttcag ctattgtttt ttatgaggat aaataaggaa catcgtattt
    17581 atgccgaaaa aatttattga tgttgagaag aacccttaac taaacttgca gacgaatgtc
    17641 ggcatagcgt gagctattaa gccgaccatt cgacaagttt tgggattgtt aagggttccg
    17701 aggctcaacg tcaataaaac aattggaata aaatcaacct acagagcatc cagctgcaaa
    17761 tgcagttccg caaactgctt cacatacacc gccggctatt ggatttacga ttgcccatac
    17821 tccacagtag tgagcacatg cataaagtcc agccatacta caagcgaatg ctttgccgtt
    17881 ccatttgaat cctgcatatg ttaccggtct gtttttatca actttttcag ccttatattc
    17941 aacgtaattt ttgttaataa gtatttttcc ctctttgttt tcagtcatac ttcttttttc
    18001 ggcaatgaat tttgtgattt ttttgttgta gttatcatat attgtttcag aaactacaat
    18061 ttcttttgtt ttttcatttt tataagcgtt attagctatg tagccatatg catttttatc
    18121 atttgcttct gtagctagat attttaattt agaatttttg tcttctagct ttattttttt
    18181 aaatccttct tttttcattt gcttttcgaa tttttgcata tcttcatttt tattttgcaa
    18241 ttgttctaga aaacttattt ctttcttggt catttgtgat acttcgatgt ttttgctttt
    18301 caatttttct ttttgatttt ctagtaaaga acttttttgt tcttcatttg cgtaagcatt
    18361 agaaaaattc gcgctaaata ccagtaggaa caaggaaatt attgaaaata attttataat
    18421 tttcatttga tacctccaag ataataagat attttaattg tataagtaag cgctttataa
    18481 aatcaatatt tattttaata tatttataaa catatttttg aaaggagtct attttatgaa
    18541 tgaaaattta gaaaaatata taaaaagttt gccactttta ggtttgttaa ttagtatttt
    18601 gttaattgtt ttattctttt ttattttaga tgttgatgaa gatttattcg tggttttttt
    18661 atactgttta ttgcctttga tagttaattt gtctatttat ggtttttatg tttttgttaa
    18721 aagaaagtaa gattatgaat aattttgttt ttaatttgta tgctttgagg gggttggaaa
    18781 acggtaggtg tatagattag atttcttgtt tttttgaaac gagtgtgaac gagtttcttc
    18841 ttgtcttgat ttttgataaa aacgccctac aggaatttag aaaaacgtgg ggaagtttta
    18901 aagaatttta tgctaatttt taatttgcat gtaaatgggc agtgtctaaa aatagttatt
    18961 gtttttgctc aaatttttgt ttttgaaaat agcatatatt tatttggctc atatttgcgt
    19021 tttaaaagca tatataagtt ttagatataa aactatatga atcaccccta aatctttaaa
    19081 atgccctctt aaaattcaaa ataagggcat aaaaaataaa agctacccca gataaagtga
    19141 ggtagctttt tctttcatac ggtctattta tttttctttc gacgccgtat cgtcgatgta
    19201 attcaaaaaa gttatgggct ataaatctac atcacttttt caagaatgta gtagcaatat
    19261 tcaacgcaaa ttaattttta taactgctcg gaatatctca agccgtttct ttaattttga
    19321 aataaaaaaa tcgacgaagg tcgattacgt ttttgcacat gtcgatttat ccgacgtata
    19381 agtgcgccct tacgggattt aactagatta taacgacgaa ttttagacct gtaaagcaat
    19441 aacaattagg tctaccaggt agataaagtg tacaaagtag aaccgaaaaa gttatttatt
    19501 ttgaagattt ttcgtagata taatttgcta ataaacttcc taaaactgaa taaagaaaaa
    19561 tagttaaact catgtaatca ctccataatt ctgaagtgtc tccatgtcta cgcatagaca
    19621 cgcatttatg ccgaaaaaat ttattgatgt tgagaagaac ccttaactaa acttgcagac
    19681 gaatgtcggc atagcgtgag ctattaagcc gaccattcga caagttttgg gattgttaag
    19741 ggttccgagg ctcaacgtca ataaagcaat tggaataaag cacctatgat tatttaaaaa
    19801 tataagttat aatacattca aaaatatttt tgaatgaggt gtatt
//
