LOCUS       NZ_CP080554            23058 bp    DNA     circular CON 14-SEP-2023
DEFINITION  Staphylococcus aureus strain HL18380 plasmid pHL18380_1, complete
            sequence.
ACCESSION   NZ_CP080554
VERSION     NZ_CP080554.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN17301233
            Assembly: GCF_019551235.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 23058)
  AUTHORS   Kim,J.-M., Chung,S.H. and Kim,J.-S.
  TITLE     Whole genome sequence of MRSA HL18380
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 23058)
  AUTHORS   Kim,J.-M., Chung,S.H. and Kim,J.-S.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-JUL-2021) Laboratory Medicine, Hallym University
            College of Medicine, 150 Seongan-ro, Gangdong-gu, Seoul 05355, South
            Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 22-APR-2020
            Assembly Method                   :: SPAdes v. 3.14.0
            Assembly Name                     :: HL18380
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 607x
            Sequencing Technology :: Oxford Nanopore MinION; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 09/14/2023 05:31:40
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,988
            CDSs (total)                      :: 2,906
            Genes (coding)                    :: 2,822
            CDSs (with protein)               :: 2,822
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 47 of 84
            Pseudo Genes (incomplete)         :: 40 of 84
            Pseudo Genes (internal stop)      :: 15 of 84
            Pseudo Genes (multiple problems)  :: 17 of 84
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP080554.1.
            Annotation performed at Hallym University College of Medicine on
            July 30, 2021 using the NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP) version 2021-01-11.build5132.  Annotation modified by
            submitter.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..23058
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="HL18380"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pHL18380_1"
                     /geo_loc_name="South Korea:Seoul"
                     /lat_lon="37.5362 N 127.1357 E"
                     /collection_date="2016"
                     /collected_by="Kandong Sacred Hospital"
     gene            join(22853..23058,1..366)
                     /locus_tag="JMO11_RS14745"
                     /old_locus_tag="JMO11_002944"
                     /pseudo=""
     CDS             join(22853..23058,1..366)
                     /locus_tag="JMO11_RS14745"
                     /old_locus_tag="JMO11_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /name="HTH domain-containing protein"
     gene            complement(535..1209)
                     /locus_tag="JMO11_RS14750"
                     /old_locus_tag="JMO11_002945"
     CDS             complement(535..1209)
                     /locus_tag="JMO11_RS14750"
                     /old_locus_tag="JMO11_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105991.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            1471..1656
                     /locus_tag="JMO11_RS14755"
                     /old_locus_tag="JMO11_002946"
     CDS             1471..1656
                     /locus_tag="JMO11_RS14755"
                     /old_locus_tag="JMO11_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001037130.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            complement(1879..2457)
                     /locus_tag="JMO11_RS14760"
                     /old_locus_tag="JMO11_002947"
     CDS             complement(1879..2457)
                     /locus_tag="JMO11_RS14760"
                     /old_locus_tag="JMO11_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690637.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(2721..3101)
                     /gene="blaI"
                     /locus_tag="JMO11_RS14765"
                     /old_locus_tag="JMO11_002948"
     ARG             complement(2725..3101)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            complement(3091..4848)
                     /gene="blaR1"
                     /locus_tag="JMO11_RS14770"
                     /old_locus_tag="JMO11_002949"
     ARG             complement(3095..4848)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            4955..5800
                     /gene="blaZ"
                     /locus_tag="JMO11_RS14775"
                     /old_locus_tag="JMO11_002950"
     ARG             4956..5797
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(6326..6745)
                     /locus_tag="JMO11_RS14780"
                     /old_locus_tag="JMO11_002951"
     CDS             complement(6326..6745)
                     /locus_tag="JMO11_RS14780"
                     /old_locus_tag="JMO11_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            6869..7840
                     /locus_tag="JMO11_RS14785"
                     /old_locus_tag="JMO11_002952"
     CDS             6869..7840
                     /locus_tag="JMO11_RS14785"
                     /old_locus_tag="JMO11_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_000481279.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            complement(8012..8104)
                     /locus_tag="JMO11_RS14790"
                     /old_locus_tag="JMO11_002953"
     CDS             complement(8012..8104)
                     /locus_tag="JMO11_RS14790"
                     /old_locus_tag="JMO11_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(8261..8608)
                     /locus_tag="JMO11_RS14795"
                     /old_locus_tag="JMO11_002954"
     CDS             complement(8261..8608)
                     /locus_tag="JMO11_RS14795"
                     /old_locus_tag="JMO11_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            complement(8627..9244)
                     /gene="cadD"
                     /locus_tag="JMO11_RS14800"
                     /old_locus_tag="JMO11_002955"
     ARG             complement(8631..9244)
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(10360..10554)
                     /locus_tag="JMO11_RS14805"
                     /old_locus_tag="JMO11_002956"
     CDS             complement(10360..10554)
                     /locus_tag="JMO11_RS14805"
                     /old_locus_tag="JMO11_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_220338224.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIALFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            10664..11356
                     /locus_tag="JMO11_RS14810"
                     /old_locus_tag="JMO11_002957"
     CDS             10664..11356
                     /locus_tag="JMO11_RS14810"
                     /old_locus_tag="JMO11_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            complement(11524..11673)
                     /locus_tag="JMO11_RS14815"
                     /old_locus_tag="JMO11_002958"
     CDS             complement(11524..11673)
                     /locus_tag="JMO11_RS14815"
                     /old_locus_tag="JMO11_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000695366.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(12218..>12508)
                     /locus_tag="JMO11_RS14820"
                     /old_locus_tag="JMO11_002959"
                     /pseudo=""
     CDS             complement(12218..>12508)
                     /locus_tag="JMO11_RS14820"
                     /old_locus_tag="JMO11_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(12528..13511)
                     /locus_tag="JMO11_RS14825"
                     /old_locus_tag="JMO11_002960"
     CDS             complement(12528..13511)
                     /locus_tag="JMO11_RS14825"
                     /old_locus_tag="JMO11_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001181107.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            13937..14680
                     /locus_tag="JMO11_RS14830"
                     /old_locus_tag="JMO11_002961"
     CDS             13937..14680
                     /locus_tag="JMO11_RS14830"
                     /old_locus_tag="JMO11_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            complement(14907..15092)
                     /locus_tag="JMO11_RS14835"
                     /old_locus_tag="JMO11_002962"
     CDS             complement(14907..15092)
                     /locus_tag="JMO11_RS14835"
                     /old_locus_tag="JMO11_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000797248.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(15097..15435)
                     /locus_tag="JMO11_RS14840"
                     /old_locus_tag="JMO11_002963"
     CDS             complement(15097..15435)
                     /locus_tag="JMO11_RS14840"
                     /old_locus_tag="JMO11_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001049146.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            complement(15681..16289)
                     /locus_tag="JMO11_RS14845"
                     /old_locus_tag="JMO11_002964"
     CDS             complement(15681..16289)
                     /locus_tag="JMO11_RS14845"
                     /old_locus_tag="JMO11_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583528.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            complement(16775..17674)
                     /locus_tag="JMO11_RS14850"
                     /old_locus_tag="JMO11_002965"
     CDS             complement(16775..17674)
                     /locus_tag="JMO11_RS14850"
                     /old_locus_tag="JMO11_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000196697.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            complement(17773..19239)
                     /gene="msr(A)"
                     /locus_tag="JMO11_RS14855"
                     /old_locus_tag="JMO11_002966"
     ARG             complement(17777..19239)
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="99.8"
                     /coverage="100.0"
     gene            19713..20387
                     /locus_tag="JMO11_RS14860"
                     /old_locus_tag="JMO11_002967"
     CDS             19713..20387
                     /locus_tag="JMO11_RS14860"
                     /old_locus_tag="JMO11_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_220338223.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKDFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            <20528..21163
                     /locus_tag="JMO11_RS14865"
                     /old_locus_tag="JMO11_002968"
                     /pseudo=""
     CDS             <20528..21163
                     /locus_tag="JMO11_RS14865"
                     /old_locus_tag="JMO11_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251744.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="aminoglycoside 6-adenylyltransferase"
     gene            21160..21690
                     /gene="sat4"
                     /locus_tag="JMO11_RS14870"
                     /old_locus_tag="JMO11_002969"
     ARG             21161..21687
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="97.78"
                     /coverage="100.0"
     gene            21783..22577
                     /gene="aph(3')-IIIa"
                     /locus_tag="JMO11_RS14875"
                     /old_locus_tag="JMO11_002970"
     ARG             21784..22574
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(16779..17674)
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(17774..19239)
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.16"
                     /coverage="100.0"
     ARG             complement(16776..17674)
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             21173..21690
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="97.16"
                     /coverage="95.56"
     ARG             20565..20866
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     ARG             4956..5800
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     Typing          complement(12016..12160)
                     /name="MOB_unknown"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="96.575"
                     /coverage="88.0"
                     /evalue="6.92e-62"
     Typing          complement(12221..12397)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.258"
                     /coverage="94.0"
                     /evalue="6.2e-68"
     Typing          complement(12529..13511)
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          13938..14680
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atgtttacag cggcggaagt gggtgcattg attacagcag ggaaattttt aaattgccat
       61 ggagatgaat catttataaa ggattttgat tcagctatgt ataaaatcaa atctattttg
      121 aagcatggtg aaaaaaacta tgcacaggag ttggagaaca gtattaacgt gtacagcaca
      181 tctggacaga aaaatacatt ggcggataac gttattgcag caattcagac tgcaatctgc
      241 aataaaaggg taatatcaat tcaatatcct gcatcaggag ggcaagaacc ggaaagcaga
      301 atgatagagc ctatatcact ggggttttat gaacagaact ggtacttaat cggttttgca
      361 ggctaagaaa tgaatatagg aattttcgtg tggatcggat taaaagcatt tgcatagaag
      421 aagagctctg tcaaagccat gatggctctt tggaacaaat attaaaacaa atgctggttc
      481 tgttgcaaag taaaaaaata tagctaacca ctaatttatc atgtcagtgt tcgcttaact
      541 tgctagcatg atgctaattt cgtggcatgg cgaaaatccg tagatctgaa gagacctgcg
      601 gttcttttta tatagagcgt aaatacactc aatacctttt aaagtattct ttgctgtatt
      661 gatactttga taccttgtct ttcttacttt aatatgacgg tgatcttgct caatgaggtt
      721 attcagatat ttcgatgtac aatggcagtc aggtttaagt ttaaaagctt taattacttt
      781 aaccattgct accttcgttg aaggtgcctg atctgtaatt accttttgag gtttaccaaa
      841 ttgtttaatg agacgtttga taaacgcata tgctgaatga ttatctcgtt gcttacgcaa
      901 ccaaatatct aatgtatgtc cctctgcatc aatggcacga tataaatagc tccattttcc
      961 ttttattttg atgtacgtct catcaatacg ccatttgtaa taagcttttt tatgcttttt
     1021 cttccaaatt tgatataaaa ttggggcata ttcttgaacc caacggtaga ccgttgaatg
     1081 atgaacgttt acaccacgtt cccttaatat ttcagatata tcacgataac tcaatgcata
     1141 tcttagatag tagccaacag ctacagtgat aacatccttg ttaaattgtt tatatctgaa
     1201 atagttcata cagaagactc ctttttgtta aaattatact ataaattcaa ctttgcaaca
     1261 gaacctcatt tactatatgg gcatctcttt cattattaat acaaagcttt gtatctccga
     1321 tattaggcaa aggtgtaaac gaattaggtg atactatagg attcaacatt atattaatcg
     1381 tttctttaat aatgattatc ttcttatttt ttataaatcg tagtaaaaat atctcctatg
     1441 attatataaa agttcaaaga ggtgaagcca atgaataaat tagaaaaatg gtctttggta
     1501 tttattattt ttacatttct ctcttcatta gcacttttat atttcaaata taattttagt
     1561 tcggttatgc cagtcctaag tctttctatt ttaactatac taatattgtt gacgagtatt
     1621 attactgtag tttcagttaa tgatgaagat acttaaaacg ttcattagtg aaacaggtat
     1681 tatattaaaa aagcgtacga atttgtacgc ttttttcttg tgttattatt aaaatctcat
     1741 aacaggaaaa tattatgaga ttttagacgc tgtcagaacg tctcttttac atcgagtgac
     1801 attgaatcaa agtctttgta tgttaatgat atataaaatt atttagtaga ttcattatag
     1861 taagctagat tagttgctct acttgttttt attctctttt gcctctaatt tattgagata
     1921 acgataaata gttgtacgtg aaacttgcca ctgctctgca attgttttaa ttggcgtacc
     1981 attatcataa agtgtcttaa gtaagtttaa atcttgttta tttaattttt caggtctacc
     2041 tccatatcgg cctctagcac gtgctgcaat tcgaccggct gatgatcgct ctaaaattaa
     2101 attacgttca aactctgcaa atgctgcgaa taaatgaaat aataattgtc ctgtagaact
     2161 tgatttatcc atcgttatat tttcttctaa actatgaaaa ctcacacctc gttcgttaag
     2221 ttcattaact aacgtgatta aatcctccat gttccgtcct agtctatcta atctccaaac
     2281 aacaatcgta tctcctgacc tcgcaaattc aattgcttta tctaaaccag gtcgcttact
     2341 ttttgaacca ctcatatggt cattaaatat cttttcacaa ccatatgtat ttaatcgatc
     2401 ctcctgtaaa ttcaaatttt gtaatccagt tgaaactctt gcataaccta ttttcaaaat
     2461 acagacctcc tatatacacc tttagtgtac cataacttga ttacgaggtc ttttgtgaac
     2521 atagattttt tgttgggttt ttgaacacat aattctatgt aatacttact tatttagaca
     2581 aaaaacaaga gtgtacagaa aatggttatt ttctggacac tctcatcttt aataatatat
     2641 tttaaatgtc attaacaaaa ctaatttaat aagagtcaag tatggtttac atatgtatta
     2701 tgtttgaaac atacctctaa ttacttttta ctaatatcat ttaaaatgtc tcgcaattct
     2761 tcaatttctt tgttatttaa ttcttcattt ttcgcaaaat tcagcactaa acttttcata
     2821 tcccctccat acagtttatt aagaaaggtt ttagcagttt tcattttaat atcgtcttct
     2881 ttaatatttg atgagtaaaa ataaatattt tctgatttgt atcgttttat aatctctttt
     2941 ttatatagtc ttgtgattaa tgttctaatc gttttatcac taacttcttt atatttttga
     3001 atttcaacta caatttcatt agctgatact gattttttat cccatattat attcataaca
     3061 tcccattcag ccatagatat ttcaacttgc ttattggtca tttaaaacac ccattccttt
     3121 taatattttt tcacttatta attcagcatt tttcccagac gggtttccat ctgataaatg
     3181 tgtagcaaaa taatacttat catgatttgt aattacgtaa cctacaaacc acccattatt
     3241 atacttcccg tttactatac ctgtacctgt tttcccatac agttcatact tttcattttt
     3301 cttaatcaat aatgaagaag ataattgatt ctttgctttt ttactaaaat ggttattttg
     3361 ttccatcata tttttaaaaa ctattacttg ttcaagatta gatattttca aactatcttc
     3421 catccaatag cttttataac ttcccaaatt ttcattacca taatttaatt gcttgagttg
     3481 agccgcagta tagttctttg gtatttgatt actaatacgt tcgaagtacc aattaactga
     3541 attttgcatt gctgtattta aatcttgttc cttattccaa gactcgaaaa gataatgttt
     3601 atgattccat gacatacgtg aatttttatc acttataata tgacggtcaa gtccaaacag
     3661 tgctaaataa attttgtaag ttgaatcagg agaatatctt tttctacttt ctttttcatt
     3721 ataaatatag tatttgtctt tcttcatgct gtacataacg aaagatccac tatttgaacc
     3781 aaaattttta ctttcatcta aaatttggta atcgctttgt aagggctttt tataattata
     3841 atcagttaag gattgcccca ttaaaaactg gctttgaatt atcatgataa aaaaagtaaa
     3901 aatacaaata aaaattagaa ttaattttga ctgctttttc agatcggctt cttttatatt
     3961 aattaatcta cttttgagta atgatttttt accattaaat gaatggctta atatattttt
     4021 gttggaaaat ggggttttta atacggagtc cataatagat tccgcataag ttttaaattc
     4081 atttttgtta atattattaa ggacaaatct atcggcttct acttcattgt catgaattat
     4141 ctttcttttt acaatatgta ctaatggatt gtaactcata ataatagaga agatattaaa
     4201 gataattaaa tgtaaagtat ctctattttt agcatgagca tattcatgca gtattatata
     4261 ttttagtctt ttatcaatta cacttttaaa atatgaacta ggaatcaaaa taatatattt
     4321 cccataccaa aaagttattg gagattgaat agcctctgct tttcgaatca caatattttt
     4381 tttatattga tggttgaaaa gtatcgtatc tattttattt ttttcatttt cgtttagata
     4441 aagtgactgt ttctttaaat atttaagata taataaggct ttcaaaaatt taaaacttaa
     4501 aataataact aaaactatcc aaataactgt gcagatatta tcaattgaat cccaattaaa
     4561 cttatggata tctgttgtga actcttgaat aggtttggtg gtatttatgt tatggttcaa
     4621 atcgtgtgac ttactttcaa ctgtgggcgc ttgattattc acattattaa attttataaa
     4681 agagaattta attgggataa aaggaattaa tccagcaagc atagttagat accaaacttt
     4741 ataatttaaa ctataattaa aatagcgttt taatatgtac ctaaaaaata ctaacaatag
     4801 aaatataaaa caaaagctta ctacgctcat tattagtaat ttagccattt tgacaccttc
     4861 tttcaaatat ttataataaa caattgacat caatattaca attgtaatat tattgattta
     4921 taaaaattac aactgtaata tcggagggtt tattttgaaa aagttaatat ttttaattgt
     4981 aattgcttta gttttaagtg catgtaattc aaacagttca catgccaaag agttaaatga
     5041 tttagaaaaa aaatataatg ctcatattgg tgtttatgct ttaaatacta aaagtggtaa
     5101 ggaagtaaaa tttaattcag ataagagatt tgcctatgct tcgacttcaa aagcgataaa
     5161 tagtgctatt ttgttagaac aagtacctta taataagtta aataaaaaag tacatattaa
     5221 caaagatgat atagttgctt attctcctat tttagaaaaa tatgtaggaa aagatatcac
     5281 tttaaaagaa cttattgagg cttcaatgac atatagtgat aatacagcaa acaataaaat
     5341 tataaaagaa atcggtggaa tcaaaaaagt taaacaacgt ctaaaagaac taggagataa
     5401 agtaacaaat ccagttagat atgagataga attaaattac tattcaccaa agagcaaaaa
     5461 agatacttca acgcctgctg ctttcggcaa gactttaaat aaacttatcg caaatggaaa
     5521 attaagcaaa aaaaataaaa atttcttact tgatttaatg tttaataata aaaacggaga
     5581 cactttaatt aaagatggtg ttccaaaaga ctataaggtt gctgataaaa gtggtcaagc
     5641 aataacatat gcttctagaa atgatgttgc ttttgtttat cctaagggcc aatctgaacc
     5701 tattgtttta gtcattttta cgaataaaga caataaaagt gataagccaa atgataagtt
     5761 gataagtgaa accgccaaga gtgtaatgaa ggaattttaa tattctaaat gcataataaa
     5821 tactgataac atcttatagt ttgtattata ttttgtatta tcgttgacat gtataatttt
     5881 gatatcaaaa actgattttc cctttattat tttcgagatt tattttctta attctcttta
     5941 acaaactaga aatattgtat atacaaaaaa tcataaataa tagatgaata gtttaattat
     6001 aggtgttcat caatcgaaaa agcaacgtat cttatttaaa gtgcgttgct tttttctcat
     6061 ttataaggtt aaataattct catatatcaa gcaaagtgac aatagcattt tacaagtatt
     6121 ttttattgtt cgattagggt aaacctaaat aatacataaa ttatattaca atatgtttat
     6181 tatagaggct aaagtatctt agaaatttgg atagtaggtt tttcgggaat aaaagtatag
     6241 ttggctttaa tatataatta agctaagcta tcatttatat ttactcgatt ataattcgca
     6301 cttcaacttt tttataacgt aaaaattaaa acgtagtttt atttatcttt agtaatatct
     6361 ttttaaacac tacagtttct tcattagtta aattagcgaa gtaatgatta ttaagttgat
     6421 aggctttctt ttctaatgtt ggccataagt cttttgcttt atttgtactg tttattagca
     6481 cagttcttct attttcatta tcagtttgac gtgttattag atcctttttg gacatcttat
     6541 ctaatattcc agatattgtt gaaggttcta aatttaaagt attaccaatc gctttaggtg
     6601 tattcaaatt actattaatc aagcaattca aaacaccata ttctgctgga gtaatattat
     6661 agggacttaa taaactttta aaatgtttaa aaactctatt ctgagaagta ctcaacaaat
     6721 aatttataca attatctaat tccacaacta aaacctctct taaatcatta gtattgactc
     6781 gcttatcata tcatgataag ttttgtagga aaatagtttt gcaacaaaaa catacttcta
     6841 caaaacaatt gtgaaagaag gctaataaat gttcaatgcg gtagtagtga gaaaaagtgc
     6901 atcaaatgtt agttataaag tagaaaaagt tgatgaatct catttatcga agggtgatgt
     6961 attagtaaaa gtggtatact cttcaataaa ttataaggat atgctagctt tacaatataa
     7021 aggcggtgta attagagatt atcctatgat tcctggtata gattttgcag gtattgttga
     7081 atcaagttcg aatgataagt ttaaagaagg cgataatgta ttagttactg gttatgatgt
     7141 tggcgtgaca catacaggtg gattttcaga atatgcacaa gtgcctggag agtggattgt
     7201 tcctattccc caagaaatgt ctattaaaga gtctatggta tatggcacag ccggttttac
     7261 ggcagcatta tcaatttttg aactagaaaa atatggaatg aatatcaaat cacaacctga
     7321 aattttagtg tctggggcta caggtggtgt gggcagtgtt gctatacaaa ttttacataa
     7381 aattggatat gaaaatatca ctgctatcgt aagaaaagaa aagcaaatag aaatcgcaaa
     7441 aaaattaggt gcaaaacaag taataataat tgaagatgat aataaaccgc ttaaaaaagg
     7501 tatttttgat tatttcttag atacagtggg gagtaatgta acattatacg gtttaaaacg
     7561 tctaaattat caaggtgttg ctactgtatg tggaaatgta gcaggaaatt cacttaacgc
     7621 taatatatta ccgtttattc ttagaggtat taaattaatt ggcattgatt ctgtatatgt
     7681 tgatcataat atccgtgaag atatatggag taagttagca aatgaatgga atataggaaa
     7741 ttcacttcta tacaatgaaa ttggatttga agaattctat aaaacgatag atcagctttt
     7801 aaaaggacaa catttaggaa gaactatttt aaaagtataa gtgtgagtat tcattaatac
     7861 atttactatt aattcaatca ttttgcattt ctctactaac cagtgttata atttatataa
     7921 cgaaaatgat taacaattaa tgcaccaatc cccacactat tgcagtagtg tggggatttt
     7981 ttcgatgctg gcttataaag tcgcctatta attatttgtt gcgtttacta agccaataag
     8041 tataatacgc aacagcacag ccactgatga ctggtgctat gatgtgaacg aaaatgatta
     8101 gcaaagtaat gcacctcctc tcttcgtcaa ttgacgcctg agagataggc gactctatta
     8161 ttataccatc tgtgaatata caagcatatc tacttccgat aagtcgtctt atgttatata
     8221 actttgtttt ttatagtatc aagacaagaa gaaactcgtt tcaaaaaccc tcatgatttt
     8281 tagagaaaaa ctctcttatt tcatcgtctt taataaaata atatgccatc tttccatctt
     8341 tataaaaatc aagtacctca tttttatata aaagccttaa atgatgtgaa gttgaagcaa
     8401 cactcatttt caatatcaaa gaaatatcac aaacacacaa ctcatcttct ttaatcaaag
     8461 ataatatgat tttcaatttc ttctcatcac aaattttttc taaaatgtta agtaatttct
     8521 tagatttatc atcttctaaa aaacttaaag cattgttaac tttatcctca tgtacacaga
     8581 tcacatcaca agtattttca taactcatat aaaatcacac cctaaattaa aatataaatc
     8641 ctaaaattgt ttgaatagtg tcattttcaa taataataaa taaacctaaa gctatataaa
     8701 taatagccat aatccaacga ctaaatttct caacaatttc tccaattcct ggaatattag
     8761 ctaatttttg tgcagtaaac accaagaaga aaattaaaat taaaaagaca aacagagtaa
     8821 gtaataaatt agtaacactt aatgtcacaa aatacggaac aaataaacca atattatcgg
     8881 cgccacaact tgctatcgta acaattgcaa ccgtaccaac taatttagac aatccttttt
     8941 cattcaattc ttttttagct ctcttttctc cttcacaatc atcataaata gccactttaa
     9001 ttccaagata aattggtatt aaacccaata aacctaatat ccacttttct ggaacataat
     9061 ttaatacaaa agctaaaaac aaactaacta atattaaaat aatagaccct aaatattgac
     9121 caacataaat atctctatat tcttttctag tctttgctct agcaaaaaat attaataaaa
     9181 ttactaataa atcaactgct gtagcaatat aaagaacagc agcagcaaca accgtttgaa
     9241 tcataataca cctcattcaa aaatattttt gaatgtatta taacttatat ttttaaataa
     9301 tcataggtgc tttattccaa ttgctttatt gacgttgagc ctcggaaccc ttaacaatcc
     9361 caaaacttgt cgaatggtcg gcttaatagc tcacgctatg ccgacattcg tctgcaagtt
     9421 tagttaaggg ttcttctcaa catcaataaa ttttttcggc ataaatgcgt gtctatgcgt
     9481 agacatggag acacttcaga attatggagt gattacatga gtttaactat ttttctttat
     9541 tcagttttag gaagtttatt agcaaattat atctacgaaa aatcttcaaa ataaataact
     9601 ttttcggttc tactttgtac actttatcta cctggtagac ctaattgtta ttgctttaca
     9661 ggtctaaaat tcgtcgttat aatctagtta aatcccgtaa gggcgcactt atacgtcgga
     9721 taaatcgaca tgtgcaaaaa cgtaatcgac cttcgtcgat ttttttattt caaaattaaa
     9781 gaaacggctt gagatattcc gagcagttat aaaaattaat ttgcgttgaa tattgctact
     9841 acattcttga aaaagtgatg tagatttata gcccataact tttttgaatt acatcgacga
     9901 tacggcgtcg aaagaaaaat aaatagaccg tatgaaagaa aaagctacct cactttatct
     9961 ggggtagctt ttatttttta tgcccttatt ttgaatttta agagggcatt ttaaagattt
    10021 aggggtgatt catatagttt tatatctaaa acttatatat gcttttaaaa cgcaaatatg
    10081 agccaaataa atatatgcta ttttcaaaaa caaaaatttg agcaaaaaca ataactattt
    10141 ttagacactg cccatttaca tgcaaattaa aaattagcat aaaattcttt aaaacttccc
    10201 cacgtttttc taaattcctg tagggcgttt ttatcaaaaa tcaagacaag aagaaactcg
    10261 ttcacactcg tttcaaaaaa acaagaaatc taatctatac acctaccgtt ttccaacccc
    10321 ctcaaagcat acaaattaaa aacaaaatta ttcataatct tactttcttt taacaaaaac
    10381 ataaaaacca taaatagaca aattaactat caaaggcaat aaacagtata aaaaaaccac
    10441 gaataaatct tcatcaacat ctaaaataaa aaagaataaa gcaattaaca aaatactaat
    10501 taacaaacct aaaagtggca aactttttat atatttttct aaattttcat tcataaaata
    10561 gactcctttc aaaaatatgt ttataaatat attaaaataa atattgattt tataaagcgc
    10621 ttacttatac aattaaaata tcttattatc ttggaggtat caaatgaaaa ttataaaatt
    10681 attttcaata atttccttgt tcctactggt atttagcgcg aatttttcta atgcttacgc
    10741 aaatgaagaa caaaaaagtt ctttactaga aaatcaaaaa gaaaaattga aaagcaaaaa
    10801 catcgaagta tcacaaatga ccaagaaaga aataagtttt ctagaacaat tgcaaaataa
    10861 aaatgaagat atgcaaaaat tcgaaaagca aatgaaaaaa gaaggattta aaaaaataaa
    10921 gctagaagac aaaaattcta aattaaaata tctagctaca gaagcaaatg ataaaaatgc
    10981 atatggctac atagctaata acgcttataa aaatgaaaaa acaaaagaaa ttgtagtttc
    11041 tgaaacaata tatgataact acaacaaaaa aatcacaaaa ttcattgccg aaaaaagaag
    11101 tatgactgaa aacaaagagg gaaaaatact tattaacaaa aattacgttg aatataaggc
    11161 tgaaaaagtt gataaaaaca gaccggtaac atatgcagga ttcaaatgga acggcaaagc
    11221 attcgcttgt agtatggctg gactttatgc atgtgctcac tactgtggag tatgggcaat
    11281 cgtaaatcca atagccggcg gtgtatgtga agcagtttgc ggaactgcat ttgcagctgg
    11341 atgctctgta ggttgatttt attccaattg ttttattgac gttgagcctc ggaaccctta
    11401 acaatcccaa aacttgtcga atggtcggct taatagctca cgctatgccg acattcgtct
    11461 gcaagtttag ttaagggttc ttctcaacat caataaattt tttcggcata aatacgatgt
    11521 tccttattta tcctcataaa aaacaatagc tgaaatatat aaccaattac tgtgtgtttg
    11581 aatttctaat acatgaatat cattctttaa aaacctatta acttgtttat ctaattgacg
    11641 atgagtaaaa gtagcgaaag ttttaatctt catgatatct ctccttttat aaaaatagca
    11701 atccttatta caatattaaa cacttttatt ttggatttta agaggctatt ttgaaggctt
    11761 agaggcaaat catataggtt tttaacttaa aaatatatac aagctcttaa aacgcaaata
    11821 tgagccaaat aaatatatgg taatttcaca aacaaaaatt tcagcaaaac cagtgactaa
    11881 ttttttaaca ctgcccattt acatgcaaat taaaaattag cataaaatcc tttaaaactt
    11941 ccacatgttt ttctaaattc ctgcagggcg ttttttatca aaaatcgaga atttttaatt
    12001 tttctctaaa aactccgtaa gagcataagg agaatttgct atcattcaaa aatgataggt
    12061 ctggcaaagc cagaaattcc aggggtttta aggtatttta aagtgatatc atacaaagct
    12121 gtactgtctt atttttgtga cactacatac agcatttgtc acaaaaataa gacagtactt
    12181 ttttataaaa aatcaacaaa aaagacatta gtcaacacta atgtcttaaa taataatttt
    12241 gcttttcgaa attccaaatt gcggtaattg aatgtgcttt ttcttcttcg tctgttgttt
    12301 tatcttcatc acttgcatta atcaaattac catcttcgac atcgtctaag tttaaaattt
    12361 tatgtttttg tttaagcaat ccaccataac ttaacatacg ttttcgatac aaaccttttt
    12421 ctaaatcact tacaatttct tgattttttt catcatcatc agttaaaaaa tcagatgatt
    12481 taaccgaata ttttgaggtc tcttcgagtg ttataaaatc atttgaatta ttgattaaag
    12541 atattatatt gtttcatgtt tttacggcgc atataaaggg catgtgtttc ttcaagttca
    12601 gttagaattg tttgcattaa ataagcttgc attgacttga ttgtttcctt ttggccttta
    12661 actcccctat catgtatagc ttttttaagt ctttttaaag aagttaatat ttcatcctca
    12721 atgtcctcta acatgtaatg catatcttca tgccttgaat taaatgattt ttttgcttta
    12781 agaataacag cctttatgat ttctaaatct ctataatcat attttaataa ataattagtt
    12841 agttgttctg ggaattcttg caatagcatt tctttatcat caaaattatg tgtaaattga
    12901 tttgaatgat ttgaatgatt actaatttca tttttgtact ttatatcatt caagtcattc
    12961 atatcattat tctcagtatc attaaagtca atgtcattaa agtcagtatc attagtgttc
    13021 gattttcgaa cttctggacg ttcgattttc gaacttctgg acgttcgatt ttcgaacttc
    13081 tggacgttcg attttcgaac ttccttctcg ccgtaaggtt caacatcgtt ttcttctttt
    13141 tctattttgt aaatatcacg ttctgtgaca ataggtttca ttaaatatag aatatttggt
    13201 ttatttaaac cacgtcgttt ttgaatgagt agaccatcgt tttctaaccc tttttttatt
    13261 tttgttaact tttctttttt acaatttaag atttccatta gcttttcatt tgaataaaca
    13321 aagtaaatgt taccatcttc atcaacccag ctatttttaa tagataaatt taagcgatca
    13381 cgtaagatag cataggctat tttcatatca ttagttagat ttttataatt ttcactggta
    13441 aagaatactt tagggatttg ataaaatctt tctttgtaat tttcttgcac tgtaaaatat
    13501 tgattttgca tgacaaaaaa cctctttcca tattttagtt tggtaagagg taataaaacg
    13561 tttttattta gctttacatt tatttaatga tttaggtgct tgcactaaga tattattcat
    13621 tatataatac aagtatcgaa aattatataa ataaacagtt tctaaacgtt ttattaccaa
    13681 accccgacta ttaccagtag ttggggtttt tgttatatta agtttattat agcactttaa
    13741 ataaacttat aaaagggaaa atatagcttt atcaagggtt tataaaccct tgataaatat
    13801 cataaacctt tcataaaccc ttgataaaaa ggttgatgga tgtttatttt tatttattaa
    13861 tcactttatt attaagcatt ataagcttat aatattttat caagggttta taaacatttt
    13921 ataaagggtt gatgatatga aaagtgtgaa aaagttgagt gaagaattag gggttagtaa
    13981 gcaaacgatt tttaataata ttaagcgatt gaatatagag acaataaaac aggaaaacac
    14041 ttcgtttatt aaagaagata ccgatataga aaaaatcatt caaagagtaa atgaaaataa
    14101 aaagaaatat ggttttgaaa gtactactga agacaaacaa aaaaaagggt cggataatat
    14161 taattttgaa tcgaaaagcg atgctcaaat agtagaaatc cttaaaaatc agattgatac
    14221 tttaaataat caaattgaaa aacaagaaag tcgtcatgaa acaacaattg aattttacag
    14281 aaaagagttg caagaaagat caaaattgct tgaaaatcag caagttctgg cattagagag
    14341 taataaaaag attcaaaaat tagaaaatca attagaaaaa gaaaaacacc ttaattatcc
    14401 ctttgataca tctactaaca ctagacaaaa cgttgatgca caagaaaaaa catatactac
    14461 taatcctgta aatattaaca gagatcagga agaaactaaa gaaacagaga ttcaatataa
    14521 ggatatatct ggaagtcaaa gcgacgaaag tacacaaggt gaagaagcaa aaaaagaaga
    14581 cgttccagct aatctaaatg acaatgatag tgatatagaa gaaaagagtg aagaaacgga
    14641 acctaaaaag gggttttgga gtcgtttgtt tggtagctaa aataattgat taggcactaa
    14701 aagttataaa attttagtgt cttttatata gtgagaactt ctggtaatca tcgattatgt
    14761 aaactaaagt atttcaaata attaactgta ttaatactct catcatgatt gcgttataaa
    14821 cgttcgttat tgagacaaaa tttaatagta ctactacaca aaaagagagt gcgaattcgc
    14881 actctctttt tgtgataaat gaatggttaa gaaaataatt catccacagt tgtatcaaac
    14941 aatcttgcca acttaaatgc taatgtcaat gtaggatcat atttattgtt ttctattgca
    15001 ttaatagttt gcctagacac ttttaattct ttacttaaag tttcttgaga aattcctttt
    15061 tgttttctat attctctaat tctatttttc attaatttaa cctttagatg tatatttttt
    15121 atttgtagta tagtaattaa acagcataag aaatagtgct acaattataa agaaaatttc
    15181 tggatattga gaaaaccaag atccttcaat acttggtgac aaacctgtaa atttaagcac
    15241 tagtgtaaat aacatacaat atacaatcca aataaaactt ttagccagta tttcaataaa
    15301 cattttacgt tgtctttcat cgtatcgatc ttgttgtcct tttttatcta atgtttctga
    15361 aggtaaatat ttgttagtta tagccgtcca taaacaagaa aaaattaaaa taataataaa
    15421 aggaattaaa ttcattataa cacctcataa atgtaaaaag tatttgacat ttatgagtgt
    15481 aaatattttt gatacaaatg tcaaatactt tttacattat aatatatttt aaaacacctt
    15541 attagtaaaa caattactat atagaaagct gcgaactcgt actctttttt cttgtataat
    15601 tattaaaatc tcaattcaat aatatgttat ggaatttgag acactgtgag agacgctcat
    15661 ttgcattgac aatcaattta tcaagataat cccttatcat gtttaattct ataaactgtt
    15721 tgtcttgtga tattaacttc tttcgcaatc ttactaatcg ctttgccttc ttctaacatt
    15781 tccaccacgc gatgataaat aacacgtttc tgtgggtctt tagcatttgg tgaataaagt
    15841 aaagggcgcc ctttatatac gcctttttcc ttcgcaactt gaatcccttg cgcttgtcga
    15901 cgtttacttt catttctctc ttgttctgaa accattgcta atatttgaat gattaaatct
    15961 ttcataaact tatccagtaa tggattgcca attacttcat tcatcatagg taagctggta
    16021 atcattaact gaacgtcttt ttcttttaaa taattcacag tttcaataat ttcatcatag
    16081 ttacgtccta aacgatcaat agattccaca acgaatcgat ctcccattct gacaaaattg
    16141 agtgcttctt gaaatacagg tctattttcc actgactttc ccgactgttt ctctgtaaag
    16201 attttctcca caccaaacgt ctttaaatta tccaattgtc tttctaaatt ttgatctatc
    16261 gatgatactc tcgcataacc tataatcatt catcttcact ccataataaa tatacaccct
    16321 aatcatacgt tttaattgtt ataatttcaa caattctttt tgtatggtta gggtgtactc
    16381 aaagtgtaca tatctataat taaaacttac taaaaataaa tatagatttt ttctttgtaa
    16441 cagaaccgtt catttgaagg tcatctctat cataaatatt taaattaact aaaaatttta
    16501 atcatctgtt taatacttat gaaatgtatt tacggtaggt attaaaattg atgaaattta
    16561 tataagtgct ttcaatgaaa atgaccgttt atttatcctc ctgatttaag gagttagaaa
    16621 tttcgaaaac gattctttcc atttgttgca tttgttccat gtccagatat ttaatacatt
    16681 atagaaaacc aaagaccatc actaattaaa cgcagtttta aaatttcatc aggattgcct
    16741 tcgtctttaa aatgggcctc ttttaatata agttctactc tttcatacct aactctttca
    16801 atgccatcgt ttcatacgcc gattctcctg attccatagc aaactcagcg ataaacattg
    16861 ggaatactgc attgagttct attatatgct ctttcattcg tggccatatt tcacctccag
    16921 ctttaccgta tgctgttata agttgctcta atccttcgtc gtcgaataca cgatggtgtc
    16981 ctataaagtc cattgatggg tcggagtggg ttgcttcagt ccagtctatg agacctgtga
    17041 cgtttgcttg gttatctacc attatatgtc ctggatgtaa gtccccatgt atcatggtcg
    17101 catgtcgagg ccatagttcg tcgttttcta accattgttt ccatctgttc cataattcat
    17161 ctgatacgcc ataagtttct ttaactttat tcattcttct ttgaaagtca ttttttattt
    17221 cttgtatggt tttgatattt atatgctgaa cgttaatgtt ttcttctggt atgttgtgta
    17281 aatctacgag tgtttcagct aatgtgttaa taaagttttc tggtaatggt ttgtgttcaa
    17341 tttcccatac ataattttgt atttctggat ctattgtggc tgcgggttta cctgtaagtt
    17401 ttgggtaagc aataaggtct tttgcatgta ctttccactt cggtatttca aatgaaacat
    17461 tcttctgtaa gaagtctacc gtttgttttt cgggttttgt tcgtttataa acgtcaggtc
    17521 ttcttggtag tctcaaaacc cattctactc catgtttatc ttttccaaat gcaacttgaa
    17581 aatcaagtcc cgattcattc aatgagattg tttgaggttg gatgtgtaat tgatattttt
    17641 ctgcacattt aataatttca ttatgtcgag tcattttatt ggatccttat ttctattata
    17701 tttttcttgt gaacgtattt tttatattga tataaatgaa cctaatattc aatataaatt
    17761 agtgtatagt ttttaagtta tatcatgaag agattgtcct gttaattccc attttttatc
    17821 tgatacatgt ttaacaaacc ttgtatcatg tgatgtaaac aaaatgattc caggatattt
    17881 attcataaac atttctaatg cttctaatgt tttaatatct aaaaaattag ttggttcatc
    17941 caaaattaac atattcgctt tcgttgaaaa taatactgct aacgataatt tcgttctttc
    18001 cccaccactc aaaacattac aagaacgatc aagtgattca tttaaaccca agttatttaa
    18061 aatagctcta ctgaatgatt ctgatgaatc cgtttcatcc attaaatatt gcaataatga
    18121 aacgtcacgc atgtcttcat aagcaagttg acgatagtat gccatttgca ctttaggaga
    18181 acaatcaatt ccctctattt ggtggtaaat agcttcaagt aaagttgtct tacctacacc
    18241 atttgcacct acgagcgcta tatttttgcc atatggtatt tggaatcgta cttgtgttag
    18301 cagtttttga cttcctttaa ccaatgttag attttgtgca atgattggat aattattatg
    18361 gatatcataa attttatttt gtgggaaatt gaattcatga taactttgtg gtttttcaac
    18421 ttcttccaaa tgttccattc ttttttcaat atgcttagct tgtttttgag cagccttctc
    18481 aaccgtgcct ttttgttttg atgcacttaa acgatctggt gctatacttt tgtttttttg
    18541 ttttgatgat gcttgtgcca tttgttgcgc ttgatttcgt ttagctttac tggcttggga
    18601 caatctttgt ttttcactta tatactgttc atattgacgt tgttgttcta actgttcttg
    18661 ttcatattga ttttgatact gtgtgtaatt acctttaaac actcttattg tgccatcttc
    18721 ttgtatatcc caaattgtgt cagcaatttg gtctataagt gctctatcat gacttactat
    18781 aattaaagta ccatagtaat attttaaaat atttttcaga taatctttac caattttatc
    18841 caagtgattt gtaggttcat ctaaaagtaa tatcggacta taatttgata tgacattagc
    18901 taatttatat tttgcttttt caccaccact catactgtcg gttgtatgca taggtatatg
    18961 gagttcactc attaaactac cgtctaacgt gttaaaatca ttttccacat ccatgttaag
    19021 ctgttcaaaa tattgaattt cgccaaccgt ttcaactgtt ccagattctg gttttgtttt
    19081 ttgagcaatc atatttagta atgtggtttt gccagtacca ttacccccaa taagtgctat
    19141 tttttcaaat tggtaagcgt aaagatgacc gatgttaagt gatcgtaaat ctgtcaattt
    19201 atgattgatt tggttaaatt taattgtata ttgttccata tttatacact ccttgtatat
    19261 ttaaaggacg tgtacgcaaa aaaatgagac aggctactcc cgtctcattc acattacact
    19321 ttcaaacact taaaaattta ttatgatgtt ttagtatttg aaagcgttta ttattcctat
    19381 cgaaggataa aaaatgacat aagtcatcct atgagtgtgt attgcggaca agcctttttg
    19441 aattaattta gttttgtatt caaaaaggtt tatttgagtc tcatagaagc tgtcatttta
    19501 atcctccttc atcgataaaa tagtaatgtt aatataacat tttgttggtt tttttacaat
    19561 atatctctaa gtagaaagat tatataacaa aagtataaaa atacaatttt agattgatta
    19621 tacatctcct taatttagag tgtactcata aaatacggtt ctgttgcaaa gttgaattta
    19681 taatataatt ttaacaaaaa ggagtcttct gtatgaacta tttcagatat aaacaattta
    19741 acaaggatgt tatcactgta gccgttggct actatctaag atatgcattg agctatcgtg
    19801 atatatctga aatattaaga gaacgtggtg taaacgttca tcattcaacg atctaccgtt
    19861 gggttcaaga atatgcccca attttatatc aaatttggaa gaaaaagcat aaaaaagctt
    19921 attacaaatg gcgtattgat gagacgtata tcaaaataaa aggaaaatgg agctatttat
    19981 atcgtgccat tgatacagag ggacatacat tagatatttg gttgcgtaag caacgagata
    20041 atcattcagc atatgcgttt atcaaacgtc tcattaaaca atttggtaaa cctcaaaagg
    20101 taattacaga tcaggcacct tcaacgaagg tagcaatggt taaagtaatt aaagatttta
    20161 aacttaaacc tgactgccat tgtacatcga aatatctgaa taacctcatt gagcaagatc
    20221 accgtcatat taaagtaaga aagacaaggt atcaaagtat caatacagca aagaatactt
    20281 taaaaggtat tgagtgtatt tacgctctat ataaaaagaa ccgcaggtct cttcagatct
    20341 acggattttc gccatgccac gaaattagca tcatgctagc aagttaaacg aacactgaca
    20401 tgatatatta gtgattagct atatttttta ctttgcaaca gaaccatcat ttttattaaa
    20461 atactctttt gtaaaatctt tctgctcttc aatgtattta atttctttac ctctaaatct
    20521 attatagcta tttgatgatt acaataaaat tgatcttacc ttattgccct tggaagagtt
    20581 agataattac ctaaagggcg ataaattaat aaaggttcta attgataaag attgtagaat
    20641 taaaagggac atagttccga ctgatataga ttatcatgta agaaagccaa gcgcaaggga
    20701 gtatgatgat tgctgcaatg aattttggaa tgtaacacct tatgttatta aaggattgtg
    20761 ccgtaaggaa attttatttg ctattgatca ttttaatcag attgttcgcc atgagctgct
    20821 gagaatgata tcatggaagg tcggcatcga aacaggcttt aaatgaagtg taggcaagaa
    20881 ctataagttt attgaaaggt atatatccga ggatttgtgg gagaaacttt tgtccaccta
    20941 ccggatggat tcctatgaaa acatatggga agcattattt ctatgccatc aattgttcag
    21001 ggcggtatcc ggtgaggtgg cggaaaggct tcattatgcc tatccggagt atgataggaa
    21061 tataacaaaa tataccaggg acatgtataa aaaatacact ggtaaaaccg gctgcctgga
    21121 tagcacatat gccgctgata tagaagagag gcgggaacag tgattacaga aatgaaagca
    21181 gggcacctga aagatatcga taaacccagc gaaccatttg aggtgatagg taagattata
    21241 ccgaggtatg aaaacgagaa ttggaccttt acagaattac tctatgaagc gccatattta
    21301 aaaagctacc aagacgaaga ggatgaagag gatgaggagg cagattgcct tgaatatatt
    21361 gacaatactg ataagataat atatctttac taccaagacg ataaatgcgt cggaaaagtt
    21421 aaactgcgaa aaaattggaa ccggtacgct tatatagaag atatcgccgt atgtaaggat
    21481 ttcagggggc aaggcatagg cagcgcgctt atcaatatat ctatagaatg ggcaaagcat
    21541 aaaaacttgc atggactaat gcttgaaacc caggacaata accttatagc ttgtaaattc
    21601 tatcataatt gtggtttcaa aatcggctcc gtcgatacta tgttatacgc caactttgaa
    21661 aaagctgttt tctggtattt aaggttttag aatgcaagga acagtgaatt ggagttcgtc
    21721 ttgttataat tagcttcttg gggtatcttt aaatactgta gaaaagagga aggaaataat
    21781 aaatggctaa aatgagaata tcaccggaat tgaaaaaact gatcgaaaaa taccgctgcg
    21841 taaaagatac ggaaggaatg tctcctgcta aggtatataa gctggtggga gaaaatgaaa
    21901 acctatattt aaaaatgacg gacagccggt ataaagggac cacctatgat gtggaacggg
    21961 aaaaggacat gatgctatgg ctggaaggaa agctgcctgt tccaaaggtc ctgcactttg
    22021 aacggcatga tggctggagc aatctgctca tgagtgaggc cgatggcgtc ctttgctcgg
    22081 aagagtatga agatgaacaa agccctgaaa agattatcga gctgtatgcg gagtgcatca
    22141 ggctctttca ctccatcgac atatcggatt gtccctatac gaatagctta gacagccgct
    22201 tagccgaatt ggattactta ctgaataacg atctggccga tgtggattgc gaaaactggg
    22261 aagaagacac tccatttaaa gatccgcgcg agctgtatga ttttttaaag acggaaaagc
    22321 ccgaagagga acttgtcttt tcccacggcg acctgggaga cagcaacatc tttgtgaaag
    22381 atggcaaagt aagtggcttt attgatcttg ggagaagcgg cagggcggac aagtggtatg
    22441 acattgcctt ctgcgtccgg tcgatcaggg aggatatcgg ggaagaacag tatgtcgagc
    22501 tattttttga cttactgggg atcaagcctg attgggagaa aataaaatat tatattttac
    22561 tggatgaatt gttttagtac ctagatttag atgtctaaaa agctttaact acaagctttt
    22621 tagacatcta atcttttctg aagtacatcc gcaactgtcc atactctgat gttttatatc
    22681 ttttctaaaa gttcgctaga tagagttcta tattagagat gtaaagagtt ttggtgaaga
    22741 ggtttgtgag tatggctttt ataaccaggg tgcaatgaga agcactaaca gcagctagct
    22801 taagaacgca taggatatac tttttatgga agtcacagag gaggaataaa atttgaacag
    22861 gattaacaga gtaacctcta ttcttattca gctgcaatca aaaaaataat tcctgccaaa
    22921 gaaattgcac agcgatttaa tataagctta aggacagttt acagagatat ccggacactt
    22981 gaagaagccg gaataccaat tggatctgag gccggaaaag gatattttct tgtagagggc
    23041 ttcctacttc tgccggta
//
