LOCUS       NZ_CP080354             5596 bp    DNA     linear   CON 04-JUN-2024
DEFINITION  Klebsiella pneumoniae strain K191663 plasmid unnamed1, complete
            sequence.
ACCESSION   NZ_CP080354
VERSION     NZ_CP080354.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN20422817
            Assembly: GCF_019443545.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 5596)
  AUTHORS   Zhang,B. and Zhou,Y.
  TITLE     ST16 K. pneumoniae in China
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5596)
  AUTHORS   Zhang,B. and Zhou,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-JUL-2021) foundation medicine, Southwest medical
            university, Longmatan District, Luzhou, Sichuan 646607, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: SOAPdenovo v. 2.04; unicycler v. 0.4.7
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019443545.1-RS_2024_06_04
            Annotation Date                   :: 06/04/2024 06:14:40
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,768
            CDSs (total)                      :: 5,635
            Genes (coding)                    :: 5,506
            CDSs (with protein)               :: 5,506
            Genes (RNA)                       :: 133
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 93
            ncRNAs                            :: 15
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 69 of 129
            Pseudo Genes (internal stop)      :: 12 of 129
            Pseudo Genes (multiple problems)  :: 11 of 129
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP080354.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..5596
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="K191663"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="unnamed1"
                     /geo_loc_name="China:wuxi"
                     /collection_date="2019-11-07"
     gene            <1..227
                     /locus_tag="K0P45_RS26425"
                     /old_locus_tag="K0P45_26410"
     CDS             <1..227
                     /locus_tag="K0P45_RS26425"
                     /old_locus_tag="K0P45_26410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="WP_200493705.1"
                     /translation="TRPARSLRLPSIDPVLLRQLAGMGNNLNQIARKINGGQWSGADRV
                     QVVAALMAIDAELERLRHAVLEKGADDDR"
                     /name="MobC family plasmid mobilization relaxosome protein"
     gene            436..>870
                     /locus_tag="K0P45_RS29000"
                     /pseudo=""
     CDS             436..>870
                     /locus_tag="K0P45_RS29000"
                     /inference="COORDINATES: protein motif:HMM:NF015397.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            905..1414
                     /locus_tag="K0P45_RS26435"
                     /old_locus_tag="K0P45_26420"
     CDS             905..1414
                     /locus_tag="K0P45_RS26435"
                     /old_locus_tag="K0P45_26420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020325392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeB family mobilization protein"
                     /protein_id="WP_032433972.1"
                     /translation="MNSLLTLAKDLEQKSKAQQQSTGEMLKAAFSEHEKSVRAELSESG
                     KRISAAIRAHEQGMSAAMQSNRLSVMRMVGRTWLTITMVSGLLFASLSGVLWYQGSLIA
                     SNLAEIDRQNAALSKLNAKTWGVTYLEDSNGRFLVLPKGTAVDRTQSWTVGNGRSKQNA
                     LRLVKE"
                     /name="MbeB family mobilization protein"
     gene            1421..1633
                     /locus_tag="K0P45_RS26440"
                     /old_locus_tag="K0P45_26425"
     CDS             1421..1633
                     /locus_tag="K0P45_RS26440"
                     /old_locus_tag="K0P45_26425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeD family mobilization/exclusion protein"
                     /protein_id="WP_021527181.1"
                     /translation="MTELEKQLLSALEQLQQDYSKRLDEWESAFGEWRKMSGLMQRENA
                     ALSERVTRLSQQVERLSGQLQRLSR"
                     /name="MbeD family mobilization/exclusion protein"
     gene            complement(2009..2137)
                     /locus_tag="K0P45_RS29070"
     CDS             complement(2009..2137)
                     /locus_tag="K0P45_RS29070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000523570.1"
                     /translation="MGLKPGPKRIADSTGEPDKRQRDNKKTPGNTDKLKPSKSSKK"
                     /name="hypothetical protein"
     gene            2300..2524
                     /locus_tag="K0P45_RS26445"
                     /old_locus_tag="K0P45_26430"
     CDS             2300..2524
                     /locus_tag="K0P45_RS26445"
                     /old_locus_tag="K0P45_26430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6290 family protein"
                     /protein_id="WP_000879771.1"
                     /translation="MLAIRLSDEIESRLDSLAKQTGRTKTFYAREAILAHLEDLEDYYL
                     SAETAARVRRGDEAVHSSEDVRKSLGLDD"
                     /name="DUF6290 family protein"
     gene            2508..2774
                     /locus_tag="K0P45_RS26450"
                     /old_locus_tag="K0P45_26435"
     CDS             2508..2774
                     /locus_tag="K0P45_RS26450"
                     /old_locus_tag="K0P45_26435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262326.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_004197762.1"
                     /translation="MVWTINYSDRALKSLRKMDKQNARRIVDFMSLRIAVAADPRQSGK
                     PLKGELGEFWRYRVGDYRVLCEIRDDELVILAATIGHRREVYD"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(2844..3194)
                     /locus_tag="K0P45_RS26455"
                     /old_locus_tag="K0P45_26440"
     CDS             complement(2844..3194)
                     /locus_tag="K0P45_RS26455"
                     /old_locus_tag="K0P45_26440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004197756.1"
                     /translation="MYWLIAFLAFIFPGRSFADGYTAYYRCNGTQEASLTVKDNKLSMV
                     VGLSKFNRQLDTYRFKEKGIEVVMQRAASDDNSEAIMSFIMPDVNNMTLLVKNNGYIIV
                     KTTCWLTKTDKQ"
                     /name="hypothetical protein"
     gene            complement(3260..3805)
                     /locus_tag="K0P45_RS26460"
                     /old_locus_tag="K0P45_26445"
     CDS             complement(3260..3805)
                     /locus_tag="K0P45_RS26460"
                     /old_locus_tag="K0P45_26445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_023317533.1"
                     /translation="MFFKRYLTEKEIYKAALPIVRLQGRVNTSLRFLSKYSDVNKNGLI
                     ALHLNLLHFISYNIHGVESLKITQAGINKAVQQSPHADEIKNIAQAIGRKGPEYIEGLI
                     RNPWGKKNDNPLIFIMSIEESIKETLNSGYMLYRVAPITEGEAAAFMDVLKQLLLFEDN
                     FRLFGRDLVYKIEKLKIR"
                     /name="hypothetical protein"
     gene            complement(3831..4157)
                     /locus_tag="K0P45_RS26465"
                     /old_locus_tag="K0P45_26450"
     CDS             complement(3831..4157)
                     /locus_tag="K0P45_RS26465"
                     /old_locus_tag="K0P45_26450"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_050516389.1"
                     /translation="MRERTNIMLDIGLKQSLQRLSNKTKMSLSDLINQRLSGSLSVEER
                     IGEKPEWMRNLDPYLANHFSNIELPLPSPLKEYQEKMDEIDSIINDMMVLKEYFRAKFY
                     DEIK"
                     /name="hypothetical protein"
     gene            complement(4515..4673)
                     /locus_tag="K0P45_RS29145"
     CDS             complement(4515..4673)
                     /locus_tag="K0P45_RS29145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_071596352.1"
                     /translation="MHEPPVQPDCCALSGNYHLESNPDGHAKTPLAAAIGNWIYTREIL
                     RGLEVGA"
                     /name="replication initiation protein"
     gene            5313..5489
                     /locus_tag="K0P45_RS26470"
                     /old_locus_tag="K0P45_26455"
     CDS             5313..5489
                     /locus_tag="K0P45_RS26470"
                     /old_locus_tag="K0P45_26455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004197757.1"
                     /translation="MQKPKKKPLVVKKRSWHPAVMANLMRQAQEEDYRREQMAELERSA
                     RSHFADIGGEDGG"
                     /name="hypothetical protein"
     gene            5479..>5596
                     /locus_tag="K0P45_RS29150"
                     /pseudo=""
     CDS             5479..>5596
                     /locus_tag="K0P45_RS29150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197764.1"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /name="plasmid mobilization relaxosome protein MobC"
     Typing          5148..5227
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="90.361"
                     /coverage="97.0"
                     /evalue="1.1100000000000001e-21"
     Typing          complement(4565..4962)
                     /name="rep_cluster_2370"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="89.526"
                     /coverage="91.0"
                     /evalue="3.03e-139"
     Typing          218..1749
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.804"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atacgcgccc ggcgcggtcg ttgcggctgc cgtccatcga tccggttttg ctgcgccagc
       61 ttgccgggat ggggaacaac ctcaaccaga tcgcccggaa aattaacggc ggccagtggt
      121 caggcgctga ccgggttcag gtggtggccg cgctgatggc cattgatgcc gaactcgagc
      181 ggctgcggca tgccgtgctg gaaaaggggg cagacgatga tcgttaagtt tcatccgcga
      241 gggcgaggcg gcggtgccgg gccggtggat tatctgctgg ggaaagaccg ccagcgcgac
      301 ggggccatcg tcctgcaggg aaagccggag gaggtccggg agcttatcga cgcctcgccc
      361 tacgccaaaa agtacacctc cggcgtcctg tcttttgctg aacaggattt accgcccggc
      421 cagcgtgaaa agctgatggc gagcttcgag cgggttctga tgcccggact cgataaagac
      481 cagtacagcg tgctgtgggt tgaacaccgg gacaaggggc ggctggaact gaattttctg
      541 gtaccgaaca cggaactgct gaccggcagg cgtctccagc cgtactacga ccgggcagac
      601 cgtccgcgca tcgatgcgtg gcagaccgtg gtgaacgggc gactggggct gcacgacccg
      661 aacgcaccgg agaaccggcg cgcgctggtg acgccatctt cgttacccaa aacgaagcag
      721 gaagccgcag aggctattac gcggggctta ctggccctcg cctcgtcagg ggagcttaaa
      781 acgcgtcagg acgtcactga ggcgctggaa agcgcaggtt ttgaggtcgt gcgcaccaca
      841 aagagcagca tcagcattgc cgacccggac ggagggcgaa acatccgact taagggagcc
      901 atctatgaac agtcttttaa cgctggcgaa ggacttagag cagaaatcga aagcgcagca
      961 gcagagtacc ggcgaaatgc tgaaagccgc attcagcgag cacgagaagt ctgtcagagc
     1021 ggaactgagc gaaagcggga agagaatcag cgccgccatc cgcgcccacg agcagggtat
     1081 gagcgcggcc atgcagtcga accgcctgag cgtgatgcgt atggtcgggc ggacatggct
     1141 gaccatcacg atggtgtcag gactgctgtt cgccagcctg agcggggtgt tgtggtatca
     1201 ggggagcttg atagcgtcaa atctggccga aatcgaccgg cagaacgcag cgctgtcgaa
     1261 gctgaacgcg aagacctggg gcgtgacgta cctggaagac agcaacggac gttttctggt
     1321 gctgccgaag gggacggccg tagacaggac gcagagctgg acggtcggga acgggcggtc
     1381 gaagcagaac gcgctgagac tggtgaagga gtaagtgccg atgaccgagc tggaaaaaca
     1441 gttgctgagc gcattagagc agctacagca ggactactcg aaaaggctgg acgagtggga
     1501 gagcgccttc ggggaatggc ggaaaatgtc agggcttatg caacgggaga acgcggcgct
     1561 gagcgagcgc gtgacgcgct tgagtcagca ggtggaacgc ttgagcgggc aactgcagcg
     1621 tttgagccgg tagtgcagcg tcatgagatg gccgtggccg cagaacgggc gcacgagcaa
     1681 cggcagcacg aaaaggaact gacggaagcg cgttcccggc agcgaagcta tgacggtccg
     1741 tcgctgggct gaaatgcagg aaaacagggt tctcatcggg catttacgct gaaaccggat
     1801 gtcattcacc tggctgcatg gctatgcagc caggtaaaat ttatctgtcg cgaacggggc
     1861 ggtttatcgg gtggtttgtt gccggtttta cctgactgcc accccgttcg cggcgaaccc
     1921 gtccggggcg gtgcgggcaa cgggtgttat gtttaatcag cgtgaacggc agatacaaaa
     1981 aagccccgga gggcttttaa ctactgactt atttttttga agatttgctg ggtttcaatt
     2041 tgtcagtatt tcccggcgtt tttttattgt cacgctggcg tttatcaggt tcccctgttg
     2101 aatcggcaat tcgtttcgga cccggcttaa gacccataat cgttatcctt tcaatagtta
     2161 agaggaaagc cctcaagcta gatatattga ccgcgttacg gattatcaag aggggctaac
     2221 aagattattt tttgttcttt taggttgatt gtggtactgt tgatatacat gtatagcaaa
     2281 tggtgttcgg gaggtttata tgcttgctat ccggttatct gatgagattg agtcccgtct
     2341 ggactcgctg gcgaagcaaa ccggcagaac aaagacgttt tatgcgcggg aagcaatact
     2401 ggcgcatctg gaagacctgg aggattatta tctttcagca gaaactgctg cacgcgttcg
     2461 ccgtggtgat gaagcagtgc attcgtctga agacgtgagg aagtcacttg gtctggacga
     2521 ttaactattc cgatcgggcg ctcaaatcgt tacgcaagat ggacaaacag aacgcacgac
     2581 ggattgtgga ttttatgagt ttacgcattg cagttgctgc cgatcctcgc cagtcaggga
     2641 agccgctcaa aggtgagctg ggcgagttct ggcgctatcg ggtgggagat tatcgcgttc
     2701 tgtgtgagat ccgagatgac gagcttgtta tccttgccgc cacgattgga catcgccgcg
     2761 aagtttacga ctgaagcccg ctatgcgggc ttttttgatg ccgacaacag gtattatggt
     2821 aaatactcga ctaactacgt gttctactgt ttgtcggttt tagttaacca gcaggttgtc
     2881 ttaacgataa tgtagccgtt atttttaact aataaggtca tattgttaac gtcaggcata
     2941 ataaaagaca ttatggcctc agagttatca tcagaagcag ctctctgcat tactacttcg
     3001 attccctttt ctttgaatct ataagtatcc agttgcctat taaacttaga aagacctaca
     3061 accatactta gtttgttatc tttaacagta agagatgctt cctgagtacc attacatcgg
     3121 tagtaagcgg tgtaaccgtc agcaaaagat cgaccgggga atataaatgc taggaacgca
     3181 attaaccaat acatagttga gaatcttggt attacacatt tcactatcct ctctttcatt
     3241 tttcgttcac catactttgt tatctgattt ttaatttttc tattttataa accaagtctc
     3301 taccaaaaag gcgaaaatta tcctcaaata ataataattg tttaagaaca tccatgaaag
     3361 cagctgcttc accctcagtt atgggagcta ctctatataa catataacct gagttaaggg
     3421 tttcttttat actttcttca atgctcatta taaatattag tggattatca tttttcttcc
     3481 cccatgggtt tctaattaat ccttcgatgt actcaggtcc tttgcgtcct attgcctgcg
     3541 caatattttt tatttcatct gcgtgagggc tttgttgtac agctttgttt atgcctgctt
     3601 gagtgatttt cagagactct acaccgtgta tgttgtatga gataaaatgt aataaattaa
     3661 gatgcaatgc aattaatcca tttttgttta catctgagta tttggataaa aaacgtaatg
     3721 aagtgttaac tctcccttga agcctaacaa ttgggagtgc tgccttgtat atttccttct
     3781 ccgttaaata ccgtttaaaa aacataattc tccgcctccg tatagcgtgc ctattttatt
     3841 tcgtcgtaaa acttagctct gaaatattcc tttagaacca tcatgtcatt aataattgaa
     3901 tctatctcat ccattttttc ttggtattct tttaatggtg aagggagcgg taactcaata
     3961 tttgaaaagt gattggcgag atagggatca aggtttctca tccattcagg cttttcgcca
     4021 atgcgttctt caactgaaag tgaacctgat aatctctggt taataagatc acttagactc
     4081 attttggttt tattcgaaag ccgttgtaag gattgcttta atcctatatc tagcatgata
     4141 tttgttcttt ctctcattac ccccccttgc tattgcgttt tttgttgcgc acaaagctac
     4201 cattgcgcat taagaaacgc aataaaaaag gagggaggga gtggtttgta catgatgtgc
     4261 agtgcgctga gggcatcagt ggcgggtgtt tttccgtggg atggatggag ctccggggat
     4321 aacagaactg acgatcattt aaaggatctt cttgagatcc tttttttctg cgcgtaatct
     4381 cttgcactgt aaacgaaaaa accgcctggg gaggcggttt gatcgaaggt taagtcagtt
     4441 ggggaactgc ttaaccgggt aactgggtat acgagaccgc agataccaaa actgttcttt
     4501 cagtgtagcc gcagttaggc acccacttca agacctctca atatctctct cgtatatatc
     4561 cagttaccaa tggctgctgc cagtggcgtt tttgcgtgtc cgtccgggtt ggactcaaga
     4621 tgatagttac cggaaagggc gcagcagtcg ggctgaacgg ggggttcgtg catacagccc
     4681 agcttggagc gaacgaccta aaccgagccg agataccagc agcgtgagct atgagaaagc
     4741 gccacgcttc ccgaaaggga aaaaggcgga acaggtatcc ggtaaacggc agggtcggaa
     4801 caggagagcg cacgagggag ccgccggaga gaaatcaccg gcatctttaa gtcctgtcgg
     4861 gtttcgtcct cctctgactt gagcgtccat ttctgtgatg ctcgtcaggg gaggcggagc
     4921 ctatggaaaa acggcaacgc cgcatccttt tctccggccc tttctgattt gagcgccttt
     4981 gctttatccc gttatccgtg agtcggtcac gcccgccgca gccgaacggc aggagcgcag
     5041 ctaccgagtg agcgaggagg cgtcatttca tctgtccgtg catggtattg cggacgctcc
     5101 tgagccacat atcacacctg ccacatgagg cactttcatg aatcgtgctc tcatgccaac
     5161 atagtaagcc agtatacaca gcgtaaacgc tgtgactggt tcagggctgc gccccgaaac
     5221 ccgctaacac cactgacgcg ctggcgcttg tccaacgccg gagcgacccg gaaaactttt
     5281 ccgtgccgtc cggcgtttgc gaaggaggga taatgcagaa gccgaagaag aagccgctcg
     5341 tcgtaaaaaa aagatcctgg catccggcag tgatggcaaa tctgatgcgt caggcacagg
     5401 aggaagatta ccgccgggag cagatggcag agcttgagcg ttcagcccgg tcacattttg
     5461 cggatatcgg aggagaggat ggcggttaag cgtacccgtt ttttaggtat ccgggtgacc
     5521 gatggggagt accagcagct gctggagcgc tgcaatggaa ggcaactggc ggtgtggatg
     5581 cgggaaacct gtctcg
//
