LOCUS       NZ_CP080110            34721 bp    DNA     circular CON 04-SEP-2023
DEFINITION  Enterobacter asburiae strain WW-19C plasmid pWW19C-KPC2, complete
            sequence.
ACCESSION   NZ_CP080110
VERSION     NZ_CP080110.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN18388147
            Assembly: GCF_019428505.1
KEYWORDS    RefSeq.
SOURCE      Enterobacter asburiae
  ORGANISM  Enterobacter asburiae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Enterobacter; Enterobacter cloacae complex.
REFERENCE   1  (bases 1 to 34721)
  AUTHORS   Ghiglione,B., Haim,M.S. and Dropa,M.
  TITLE     Characterization of Emerging Pathogens Carrying KPC-2 Gene in IncP-6
            Plasmids Isolated from Urban Sewage in Argentina
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 34721)
  AUTHORS   Ghiglione,B., Haim,M.S. and Dropa,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUL-2021) Microbiology, University of Buenos Aires,
            Faculty of Farmacy & Biochemistry, Junin Street 956, Buenos Aires,
            Buenos Aires C1113 AAD, Argentina
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. v0.4.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 117X
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 09/04/2023 11:04:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,234
            CDSs (total)                      :: 5,114
            Genes (coding)                    :: 4,977
            CDSs (with protein)               :: 4,977
            Genes (RNA)                       :: 120
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 51 of 137
            Pseudo Genes (incomplete)         :: 91 of 137
            Pseudo Genes (internal stop)      :: 24 of 137
            Pseudo Genes (multiple problems)  :: 24 of 137
            Pseudo Genes (short protein)      :: 1 of 137
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP080110.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..34721
                     /organism="Enterobacter asburiae"
                     /mol_type="genomic DNA"
                     /strain="WW-19C"
                     /isolation_source="raw sewage"
                     /db_xref="taxon:61645"
                     /plasmid="pWW19C-KPC2"
                     /geo_loc_name="Argentina: Buenos Aires"
                     /lat_lon="34.715694 S 58.505958 W"
                     /collection_date="2018"
                     /collected_by="AySA"
     gene            1..1377
                     /locus_tag="KZX48_RS25815"
                     /old_locus_tag="KZX48_25805"
     CDS             1..1377
                     /locus_tag="KZX48_RS25815"
                     /old_locus_tag="KZX48_25805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020309008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="WP_033996214.1"
                     /translation="MGQAQLRLFSPADEAGCYHDTARQGFFSLLMATCEGSGKKQDSYR
                     LSQMPVVLSMLDHSRDTWLSQAEFIKPNRRVVNLARIGLLFADLDTYREPWAQGRSPEQ
                     LAAAVMFRCYDEGVPPPSILVFSGRGVQAKWLLDGTLPRQALPRWNACQRYLIDRLAGL
                     GADPAAKDASRVLRLVNTVNSKSGEVCRVIHVEQGPDGEPIRYNFEYLAEALLPVARWD
                     IEADRKARADRRQFKLLPGGQTGNLRTLNGRQLAWDRLEDLRTLAALRGGVAEGERMQH
                     LFWRLNFLLLSGATHTGQMYHEAAALARELDPRWNYRSAELMTLYAKAKAHEAGEKVEF
                     GGKQFAPLYTPKNDTLISLFHITDDEQRKLRTLISRDMAAERHSEREKARRRAAGAVDR
                     ASYLEAASAKQAQALALKAQGLSVRAIAAQMGISKTAAGRYIAEPGECPKSMRITGGEG
                     "
                     /name="replication protein"
     gene            1667..1831
                     /locus_tag="KZX48_RS25820"
                     /old_locus_tag="KZX48_25810"
     CDS             1667..1831
                     /locus_tag="KZX48_RS25820"
                     /old_locus_tag="KZX48_25810"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_153302083.1"
                     /translation="MSRARRSFPPALLDSLRAMTVQETLDRLGLYWKREPGFVPVKEGF
                     GEQWNQKPT"
                     /name="hypothetical protein"
     gene            complement(1835..>2542)
                     /locus_tag="KZX48_RS26355"
                     /old_locus_tag="KZX48_25815"
                     /pseudo=""
     CDS             complement(1835..>2542)
                     /locus_tag="KZX48_RS26355"
                     /old_locus_tag="KZX48_25815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003150544.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /name="recombinase family protein"
     gene            complement(2576..5563)
                     /locus_tag="KZX48_RS25830"
                     /old_locus_tag="KZX48_25820"
     CDS             complement(2576..5563)
                     /locus_tag="KZX48_RS25830"
                     /old_locus_tag="KZX48_25820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003935408.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="WP_000124024.1"
                     /translation="MARRQILSLSERESLLALPDDELTLTRMAYFSEQDLAFINAHRKP
                     ASRFGFAVLLCYLKNIGFAPDKKSSPPAELLRVIGNRLKLSAELWQEYISGRDTTRREH
                     LGELYRYLELKAFNGALQKECIQHLLPLSTRTDRGILIAEELLKRLHQQRIIIPGIDVV
                     ERTCAEAMTLGDKAVYTTLNAHLSITHKSALDALLVTTEKQISRLTWLLQPPGKINGKN
                     VLQHIDRLNAIEALALPEGVDKTVHQNRLLKLAREGRKMSSRDLADFSPARRYATMVCV
                     LTEARATIIDEIIELHERILGSMFSRAKRQQAERLQKTGKLIQQKLRQYVSVGQAILDA
                     RNAGEDPLSAVEQILPWEDFAASLEETRLLARKDNFEPLHLITEKFSTLRKYSSRLLSA
                     LQLRATPAALSLNDALDTIREMYRKQLRKVPSSASLDFIPESWKKMVITPSGIDRQYYE
                     ICAMNELKGALRAGDIWIRGSRRYKNFDDYLMPGDNFEKLLNNNQLNIPVETDCEAYLK
                     ARLTLLASRLEEVNAMAVTGDLPDVDISDKGLKITPLDNSVPSTISPLADLIYNMLPHP
                     KITEILDEVERWTAFSRHFTHLKNPLTRPQDNRLLLTTILADGINLGLTKMAESCPGTT
                     RASLENMQAWYIRDETYSAALAELVNAQKSRPLAALWGDGSTSSSDGQNFRVGSHGRYA
                     GQVNLKYGQEPGVQFYTHISDQYSPFYTKVISRVRDSTHVLDGLLYHESDLEITEHYTD
                     TAGFTEHVFALMHLLGFAFAPRIRDLHDKRLFIQGKADKYPALQSIISTTQLNIKEIET
                     HWNEILRLATSIKQGTVTASLMLKKLASYPKQNGLAKALREIGRIERTLFMLDWFRDPS
                     LRRRVQAGLNKGEARNALARAVFMHRLGEIRDRGLENQSYRASGLTLITAAITLWNTVY
                     IENAVNLLKRKGLHLNEQLLSHLSPLGWEHINLTGDYIWRNNKKLAEGKYRPLRPVDIS
                     QYKKQP"
                     /name="Tn3 family transposase"
     gene            5731..6372
                     /locus_tag="KZX48_RS25835"
                     /old_locus_tag="KZX48_25825"
     CDS             5731..6372
                     /locus_tag="KZX48_RS25835"
                     /old_locus_tag="KZX48_25825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009651826.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_058671571.1"
                     /translation="MFIRAYLRASTEDQFADRAKEMLEQFVQERGHKIASYYRENISGT
                     KLDRPELGRLLMDSHRNDILLVEQIDRLTRLSNSDWMTLKKQIEQHELRIVSLDVPTSW
                     QALSEKDPSQADPITRAVITAINNMLIDLMAAMSHKDWLSRRQRQQQGIKRAHSLGKYR
                     GKQADQERHQKVLYYRQVKKLSIRETAEATGYSSSQVCRIQALNKITGTD"
                     /name="recombinase family protein"
     gene            6487..7299
                     /locus_tag="KZX48_RS25840"
                     /old_locus_tag="KZX48_25830"
     CDS             6487..7299
                     /locus_tag="KZX48_RS25840"
                     /old_locus_tag="KZX48_25830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000100193.1"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="WP_000100193.1"
                     /translation="MSSVSKRNGKGFFSGAVIGALGGLIGLGGAEFRLPVLIGSFKIPT
                     LEAVIFNKAMSLAVVAIALIFRTKSIAPDQLVEHLDIVMNLLAGSLIGAWWAAGRAIKM
                     SRIWLDRIILILLVLLSFVMFSEAWLPLHSISGGLFQPGIATIIAGVISGFFIGIVAAL
                     LGVAGGELLIPTIVILFGVDIKLAGSLSLMISLPTMIVGFSRYTNADAFQILKKERPLF
                     VWMVIGSVIGAAIGGLLVGLFPVKVLMTLLGVILLISAIKTFKHTRQK"
                     /name="sulfite exporter TauE/SafE family protein"
     gene            7319..7690
                     /locus_tag="KZX48_RS25845"
                     /old_locus_tag="KZX48_25835"
     CDS             7319..7690
                     /locus_tag="KZX48_RS25845"
                     /old_locus_tag="KZX48_25835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009651828.1"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_001034147.1"
                     /translation="MNKKALISDFILVRPRIYINDNISLGPGKIDLLRAIDGFHSLSAA
                     AKDLGIPYKRAWLLIDTLNKGIGKPVVITSTGGSKGGGSVLTPLGQNLLSWYDKAEANL
                     NEQSQQDLQDLEKIIFGEK"
                     /name="LysR family transcriptional regulator"
     gene            complement(<7776..8003)
                     /locus_tag="KZX48_RS25850"
                     /old_locus_tag="KZX48_25840"
                     /pseudo=""
     CDS             complement(<7776..8003)
                     /locus_tag="KZX48_RS25850"
                     /old_locus_tag="KZX48_25840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003150544.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /name="recombinase family protein"
     gene            8205..8444
                     /locus_tag="KZX48_RS25855"
                     /old_locus_tag="KZX48_25845"
     CDS             8205..8444
                     /locus_tag="KZX48_RS25855"
                     /old_locus_tag="KZX48_25845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix domain-containing protein"
                     /protein_id="WP_003089107.1"
                     /translation="MNTIRWNVAVSADTDQSLRMFLASQGGGRKGDLSRFIEEAVRAHI
                     LELSAEQAKAANAHLSEAELTNAVDEALDWARKR"
                     /name="ribbon-helix-helix domain-containing protein"
     gene            8444..8854
                     /locus_tag="KZX48_RS25860"
                     /old_locus_tag="KZX48_25850"
     CDS             8444..8854
                     /locus_tag="KZX48_RS25860"
                     /old_locus_tag="KZX48_25850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003150546.1"
                     /GO_function="GO:0005515 - protein binding [Evidence IEA];
                     GO:0004521 - RNA endonuclease activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative toxin-antitoxin system toxin component,
                     PIN family"
                     /protein_id="WP_003150546.1"
                     /translation="MRVVLDTNILFSALISPHGAPDAIYRAWRAARFEVVTSRMQLDEI
                     RRASRYPKLQAILQPAKVGAMINNLQRAVVLERLTIEVEADDPDDSFLLAMALAGDADY
                     LVTGDRRAGLLQRGHIERTRIVTPAVFCVEVL"
                     /name="putative toxin-antitoxin system toxin component, PIN
                     family"
     gene            8858..11851
                     /locus_tag="KZX48_RS25865"
                     /old_locus_tag="KZX48_25855"
     CDS             8858..11851
                     /locus_tag="KZX48_RS25865"
                     /old_locus_tag="KZX48_25855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003089110.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="WP_033995769.1"
                     /translation="MPVGFLTQEQRDGFGRYVDSPSREELERYFHLSDEDREAIQVLRG
                     NHNRLGYAVLLTTVRFVGVLPDKPAAVPVEVLQVLCRQLAIPDPDCLQRYSDHRRWIHA
                     TDIQNRFGYRHFTDPGIGFRLSRWLYALCWTGTDRPGVLFERATSWLFTQKVLLPGVSQ
                     LERFIAQLRSRVEERLWFTLGRSVTEEQRLQLQDLLTVAEGNRSSRLDQLRSGPVMVSG
                     PALIRALRRLDDVRGIGITLPAAAHIPPSRIAALARFANTAKVTAINRLPASRRMATLV
                     AFALCLEATAHDDALEVLEALLRDLFSNAEKADKKARMRSLKDLDRSAATLAAACKVVL
                     DSSISDDNVRARLFNDLPRTTLEKALEEVNALIRPVDDVYFLALEARYRSVRRFLPDLL
                     KHIRFGFSPAGKGVAASLEWLQLNLPRRKPEDDAPQEIVAKAWQKHITREDGSLDMGAY
                     VFCTLDALRTALRRHDVFVSPSWRYADPRLGLLDGAEWLAARPIICRSLGLTIDAKTTL
                     DALSVELDATWLAVAARLPDNPAIQLSENTEGKTELSLGALDKLDEPCSLLQLRAAVSD
                     LMPRVDLPEILLEIAARTGFSEAFTHVSERNARADNLVTSLCAVLLGGACNTGLEPLIR
                     TDNPALRRDRLSWVSQNYIRDDTLSAANAILVGAQSQLELAQVWGGGEVASADGMRFVV
                     PVRTVHAGPNPKYFGTGRGVTWYNLISDQFSGLNAITVPGTLRDSLVLLAVVLEQQTEL
                     QPTQIMTDTGAYSDVVFGLFRLLGYHFSPRLADVGGTRFWRTRPDADYGKLNGLARQSV
                     KLDLIAEHWDDLLRLAGSLKLGRVPATGIMRTLQTGDRPTRLAQALAEFGRIEKTLHTL
                     TYIDDESKRRATLTQLNRGEGRHSLARAVFHGKRGELRQRYREGQEDQLGALGLVVNII
                     VLWNTLYMTAAVERLKQHGYPVLEEDLARLSPLIYEHINMLGRYSFAVPEEVARGELRP
                     LRNPDDDL"
                     /name="Tn3 family transposase"
     gene            complement(11864..12076)
                     /locus_tag="KZX48_RS26285"
     CDS             complement(11864..12076)
                     /locus_tag="KZX48_RS26285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003089113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDCCVxC domain-containing (seleno)protein"
                     /protein_id="WP_003089113.1"
                     /translation="MSAIVLESVLTCPRCGFAKPETMPTDACQFYYECSNCKALLRPNP
                     GDCCVFCSFGSVKCPPIQQQLGCCS"
                     /name="GDCCVxC domain-containing (seleno)protein"
     gene            complement(12084..12359)
                     /gene="merP"
                     /locus_tag="KZX48_RS25870"
                     /old_locus_tag="KZX48_25860"
     CDS             complement(12084..12359)
                     /gene="merP"
                     /locus_tag="KZX48_RS25870"
                     /old_locus_tag="KZX48_25860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003150552.1"
                     /GO_function="GO:0045340 - mercury ion binding [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mercury resistance system periplasmic binding
                     protein MerP"
                     /protein_id="WP_003150552.1"
                     /translation="MRKLLIAVLFALPFVALAAPPKTVTLDVQNMTCGLCPITVKKSLE
                     KVSGVSDVQVNFDQKTATVTYDPDKAQPEALTEATANAGYPSTVQK"
                     /name="merP"
     gene            complement(12372..>12587)
                     /locus_tag="KZX48_RS25875"
                     /old_locus_tag="KZX48_25865"
                     /pseudo=""
     CDS             complement(12372..>12587)
                     /locus_tag="KZX48_RS25875"
                     /old_locus_tag="KZX48_25865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009682418.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="mercuric transporter MerT family protein"
                     /name="mercuric transporter MerT family protein"
     gene            complement(12865..13869)
                     /locus_tag="KZX48_RS25880"
                     /old_locus_tag="KZX48_25870"
     CDS             complement(12865..13869)
                     /locus_tag="KZX48_RS25880"
                     /old_locus_tag="KZX48_25870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110-like element IS4321 family transposase"
                     /protein_id="WP_000427620.1"
                     /translation="MENIALIGIDLGKNSFHIHCQDRRGKAVYRKKFTRPKLIEFLATC
                     PATTIAMEACGGSHFMARKLEELGHFPKLISPQFVRPFVKSNKNDFVDAEAICEAASRP
                     SMRFVQPRTESQQAMRALHRVRESLVQDKVKTTNQMHAFLLEFGISVPRGAAVISRLST
                     LLEDNSLPLYLSQLLLKLQQHYHYLVEQIKDLESQLKRKLDEDEIGQRLLSIPCVGTLT
                     ASTISTEIGDGKQYASSRDFAAATGLVPRQYSTGGRTTLLGISKRGNKKIRTLLVQCAR
                     VFIQKLEHQSGKLADWVRDLLCRKSNFVVTCALANKLARIAWALTARQQTYVA"
                     /name="IS110-like element IS4321 family transposase"
     gene            complement(14176..14352)
                     /locus_tag="KZX48_RS25885"
                     /old_locus_tag="KZX48_25875"
     CDS             complement(14176..14352)
                     /locus_tag="KZX48_RS25885"
                     /old_locus_tag="KZX48_25875"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_219773556.1"
                     /translation="MHEQKDKKRRLGFMIGKSNATLPADEQTEAELDQEVLKLFYPNQC
                     TKDTIGVASEFGN"
                     /name="hypothetical protein"
     gene            14647..15498
                     /locus_tag="KZX48_RS25890"
                     /old_locus_tag="KZX48_25880"
     CDS             14647..15498
                     /locus_tag="KZX48_RS25890"
                     /old_locus_tag="KZX48_25880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_064167154.1"
                     /translation="MFNIENNREILKSQIPLKPYATNDLEFGLTIQNKNKALDMLYLQV
                     NHPLYLHTMIFDLDKENCFYEFENAHLPIPSFITKSPDSGRCHYGYMLNAPISSTEKSR
                     QKPVKFARALYYNMATRLGADLGYAGLITKNPLHSHWSPFWSGADLYELNDLADCFDDL
                     EDPKKRENTGLAFGRNVEMFDTIRQWAYKNVLKYQSESSFNDFHNELLLKCQMHNAYLN
                     ADDLLPYNEIKATAKSIAKFCWKEFSEEKLNKIQSKKQSYRGKKNKGIVKSKTRKFLEA
                     IK"
                     /name="replication initiation protein"
     gene            15495..15767
                     /locus_tag="KZX48_RS25895"
                     /old_locus_tag="KZX48_25885"
     CDS             15495..15767
                     /locus_tag="KZX48_RS25895"
                     /old_locus_tag="KZX48_25885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_023312618.1"
                     /translation="MKVKNRKRELTAKEYAEQYEISVRTVKRYFSQDREDYEKEAKQRR
                     LKAFVLRESGMKWAEVGIALGTTKHGAIALYKRYQQIDAPTTKEA"
                     /name="hypothetical protein"
     gene            complement(15776..17260)
                     /locus_tag="KZX48_RS25900"
                     /old_locus_tag="KZX48_25890"
     CDS             complement(15776..17260)
                     /locus_tag="KZX48_RS25900"
                     /old_locus_tag="KZX48_25890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="WP_074192909.1"
                     /translation="MKGNVAKTGRSFKNRVEYILKDDHDFICSNMASDYNNVSDLTDEF
                     KTVSSFRQDIKKPVFHAFLSLPKNEHLTDEQWQEIAKDYLKEMNINIEKHQYICVRHND
                     TDQDHIHIVANRVGLDGSVWLGQHSAFNTIAACERLEIKHGLTITDGLKGQKSDVSAPT
                     KAEIEQALRTGEKPARLVLQNALQAALVGKPDLSTFVERLQAVGIEPRFNVASTGNVAG
                     VSFSVGDVAFKGSQLGKKYSWNTIKNKVIYDKNRDDELVRRFAARKTDDENSIRRSPTE
                     PDFNDSRAVDRIDDDTIGVSQHGIKPDTTDTYEGEQLIRSNNNSFKLSEKYNRPASHKV
                     RRTTQKAAQILNRVKKQYNKEPIKTYNKNGLNSWRDKSDSGSIGRILDHAETANAATYS
                     FRLKSGSRFNSRATKIEEIRDKLGIKKPVIQPKNKEKIVKEEIKKKPLGLSMNENRFKS
                     KLKETLKKEKPRNETTPTQLQQEDDQHLKPRGFKPR"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(17257..17628)
                     /gene="mobC"
                     /locus_tag="KZX48_RS25905"
                     /old_locus_tag="KZX48_25895"
     CDS             complement(17257..17628)
                     /gene="mobC"
                     /locus_tag="KZX48_RS25905"
                     /old_locus_tag="KZX48_25895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="WP_064167157.1"
                     /translation="MDTDRKRGRKGLNHEVRRDISIQFRVNKAEFDYLKELVEASGLER
                     GHYIRKEILNSEPIVKRKMPDFEQSLFKEIQHQGNNINQIAKKLNTNEDFKQSLAAEAN
                     FAIKQLMKRILKACEVYTV"
                     /name="mobC"
     gene            complement(17615..17875)
                     /locus_tag="KZX48_RS25910"
                     /old_locus_tag="KZX48_25900"
     CDS             complement(17615..17875)
                     /locus_tag="KZX48_RS25910"
                     /old_locus_tag="KZX48_25900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_074192910.1"
                     /translation="MNENDIDQSLLELLARYFYYIDPNEENTAFLEANKDEQDLCYFVA
                     YRYIKENKTQDLIDALKNQKDEDYIKAMKDYVYGGGKYGYR"
                     /name="hypothetical protein"
     gene            <18955..19572
                     /locus_tag="KZX48_RS25915"
                     /old_locus_tag="KZX48_25905"
                     /pseudo=""
     CDS             <18955..19572
                     /locus_tag="KZX48_RS25915"
                     /old_locus_tag="KZX48_25905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017413030.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /name="replication protein"
     gene            20106..20384
                     /locus_tag="KZX48_RS25920"
                     /old_locus_tag="KZX48_25910"
     CDS             20106..20384
                     /locus_tag="KZX48_RS25920"
                     /old_locus_tag="KZX48_25910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_013213990.1"
                     /translation="MIHTANRTFHQLYREWIRERREHMHNVLTWERDRYGARLVGLFYR
                     YCKVANPFPRCTLNTRINYRAHAVNLPDWPARSLELNKMWLSWREKK"
                     /name="hypothetical protein"
     gene            20495..20920
                     /locus_tag="KZX48_RS25925"
                     /old_locus_tag="KZX48_25915"
     CDS             20495..20920
                     /locus_tag="KZX48_RS25925"
                     /old_locus_tag="KZX48_25915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="WP_013213989.1"
                     /translation="MMQTELNPLICSLVATPRRMAAMPRYVGRFYVVFESMLYQQMKGL
                     CREYRGAYWLMWELSNGGFYMAPGRRDEMLNIEAMNYFSGQMSADAAGITACLYLYSHL
                     SFHTEGADQERFSRLYHSLRDWACEHDEKEAILAAID"
                     /name="antirestriction protein"
     gene            21048..21203
                     /locus_tag="KZX48_RS25930"
                     /old_locus_tag="KZX48_25920"
     CDS             21048..21203
                     /locus_tag="KZX48_RS25930"
                     /old_locus_tag="KZX48_25920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_013213988.1"
                     /translation="MNTDIVSLAKHIGDALTARRPVHMPRMKMRELGLLLIELKAYREA
                     AATVTH"
                     /name="hypothetical protein"
     gene            21249..21545
                     /locus_tag="KZX48_RS25935"
                     /old_locus_tag="KZX48_25925"
     CDS             21249..21545
                     /locus_tag="KZX48_RS25935"
                     /old_locus_tag="KZX48_25925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="WP_013213987.1"
                     /translation="MIRPETLRPFAEDWQAPTADEIKEVLELIRQRKGLSKPLSGVDVA
                     DLVGLPGERGSGKGTRTFRRWVSKTNPSPIAYGAWSILAHLAGFGAIWDADRD"
                     /name="transcriptional regulator"
     gene            <21649..22530
                     /locus_tag="KZX48_RS25940"
                     /old_locus_tag="KZX48_25930"
                     /pseudo=""
     CDS             <21649..22530
                     /locus_tag="KZX48_RS25940"
                     /old_locus_tag="KZX48_25930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152397.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element ISKpn6 family transposase"
                     /name="IS1182-like element ISKpn6 family transposase"
     gene            complement(22780..23661)
                     /locus_tag="KZX48_RS25945"
                     /old_locus_tag="KZX48_25935"
     CDS             complement(22780..23661)
                     /locus_tag="KZX48_RS25945"
                     /old_locus_tag="KZX48_25935"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015256839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbapenem-hydrolyzing class A beta-lactamase
                     KPC-2"
                     /protein_id="WP_004199234.1"
                     /translation="MSLYRRLVLLSCLSWPLAGFSATALTNLVAEPFAKLEQDFGGSIG
                     VYAMDTGSGATVSYRAEERFPLCSSFKGFLAAAVLARSQQQAGLLDTPIRYGKNALVPW
                     SPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGPAGLTAFMRSIGDTTFRLDR
                     WELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQQFVDWLKGNTTGNHRIRA
                     AVPADWAVGDKTGTCGVYGTANDYAVVWPTGRAPIVLAVYTRAPNKDDKHSEAVIAAAA
                     RLALEGLGVNGQ"
                     /name="carbapenem-hydrolyzing class A beta-lactamase KPC-2"
     gene            complement(23883..24485)
                     /gene="bla"
                     /locus_tag="KZX48_RS25950"
                     /old_locus_tag="KZX48_25940"
     CDS             complement(23883..24485)
                     /gene="bla"
                     /locus_tag="KZX48_RS25950"
                     /old_locus_tag="KZX48_25940"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015873518.1"
                     /GO_function="GO:0008800 - beta-lactamase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]; GO:0046677 - response to antibiotic
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase"
                     /protein_id="WP_078207265.1"
                     /translation="MTLINASIILKNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNT
                     AANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRK
                     LLTGELLTLASRQQLIDWMEADKVTGPLLRSALPAGWFIADKSGAGERGSRGIIAALGP
                     DGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW"
                     /name="bla"
     gene            complement(24608..25588)
                     /locus_tag="KZX48_RS25955"
                     /old_locus_tag="KZX48_25945"
     CDS             complement(24608..25588)
                     /locus_tag="KZX48_RS25955"
                     /old_locus_tag="KZX48_25945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013213985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS481-like element ISKpn27 family transposase"
                     /protein_id="WP_013213985.1"
                     /translation="MTQALHSQARTTHLIREEIRNSTLPQAELARMYNVTRQTIRKWQN
                     RESPEDKSHAPNKMYTTLTPEQELIVVELRKTLLLPTDDLLAVTREFINPAVSRAGLGR
                     CLRRHGVSDLRNLVEQEGTAPATKKTFKDYEPGFVHIDIKYLPQMPDETARRYLFVAID
                     RATRWVFIELYADQTDGSSGDFLNKVQQACPVKIVKLLTDNGSQFTDRFTAGGKKKEPS
                     GTHVFDRLCKQLGIEHRLIPPRHPQTNGMVERFNGRISDIVNQTRFGSAAELESTLRNY
                     VKIYNHSIPQRALQHKTPVQALKEWHEKRPELFRKRVYNQPGLDI"
                     /name="IS481-like element ISKpn27 family transposase"
     gene            complement(25711..26268)
                     /locus_tag="KZX48_RS25960"
                     /old_locus_tag="KZX48_25950"
     CDS             complement(25711..26268)
                     /locus_tag="KZX48_RS25960"
                     /old_locus_tag="KZX48_25950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221001.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001217881.1"
                     /translation="MRIFGYARVSTSQQSLDIQIRALKDAGVKANRIFTDKASGSSTDR
                     EGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMG
                     QMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTGATE
                     IAHQLSIARSTVYKILEDERAS"
                     /name="recombinase family protein"
     gene            26431..>26808
                     /locus_tag="KZX48_RS25965"
                     /old_locus_tag="KZX48_25955"
                     /pseudo=""
     CDS             26431..>26808
                     /locus_tag="KZX48_RS25965"
                     /old_locus_tag="KZX48_25955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495017.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4158 domain-containing protein"
                     /name="DUF4158 domain-containing protein"
     gene            complement(26822..28096)
                     /locus_tag="KZX48_RS25970"
                     /old_locus_tag="KZX48_25960"
     CDS             complement(26822..28096)
                     /locus_tag="KZX48_RS25970"
                     /old_locus_tag="KZX48_25960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011222061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4-like element ISApu2 family transposase"
                     /protein_id="WP_045892401.1"
                     /translation="MTIINATQYLKQLLSSSELNRIGKFTGFCQRLRDIQPARLLPALL
                     SGLGCDKVDGIAGLHRHFNALQLHDTDQIAYKPFHNQLRKQGFPLFMRALVERAIALRL
                     KECLPDAHGLAGFEQVLLQDGSSFALHPQLAEHFPGRFNKHSPAAVECHMTMSLLDQSP
                     ISMSITADTESERKHLPAENSLNNKLLLADAGYISREYFADVTKAKGSYLVRGSQNLNP
                     KVQAAYRQDGREMPKLLGKKLKDIDRRSCRAEVLDLDVSSGKYKYRLIRRWFAEEKRFC
                     IWMTNLPRERWPAEKVMALYRCRWQIELLFKELKSHNRLKAFATRQKAIAEGLIWASLL
                     ALLVKRRLALTLIGSAELSMLKIAKNSALWLMPILASIIHGAWQEITEKLEWAMVYLSK
                     NGKKSRQRKSKQNNTLDGIINSLAA"
                     /name="IS4-like element ISApu2 family transposase"
     gene            28253..28624
                     /locus_tag="KZX48_RS25975"
                     /old_locus_tag="KZX48_25965"
     CDS             28253..28624
                     /locus_tag="KZX48_RS25975"
                     /old_locus_tag="KZX48_25965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019838990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004099020.1"
                     /translation="MTQERIQTRYPLGGPFATQAELEQAITQAITTHRQDFFPLLERLV
                     DVGDTRVNLSQENPLRVLSIELADGREGVAHINYESNFAESCLIINEYDQHQTSLAFRL
                     DGDALIFDVELPIAWNFNN"
                     /name="hypothetical protein"
     gene            28942..30210
                     /locus_tag="KZX48_RS25980"
                     /old_locus_tag="KZX48_25970"
     CDS             28942..30210
                     /locus_tag="KZX48_RS25980"
                     /old_locus_tag="KZX48_25970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011191342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4-like element ISApu1 family transposase"
                     /protein_id="WP_011191342.1"
                     /translation="MTIINANYYLEQLLAPAALERIARLCKFCLRQRAITPAMLVPALL
                     RAMGGDQVNDIAGLHRHFNALQLVNTHQVSYKPFHNQLRKESFALFMKALVERAIALRI
                     DHQLKAASLGAFKQVLLHDGTSFAVHRRLAADFPGRFKTISPAAIECHMTMSLSEQSPL
                     CMSVSADTAGERQFLPEAHTLTNCLLLADAGYIDRAWFEQVNDAGGFYLVRGTKSLNPK
                     IIQAWRGDGREVPKLAGLSLREAGRRRCRAEVLDMVVKSGQVEYRLIRRWFAEEKRFCL
                     WMTNLPRAAWSAEQVMSLYRCRWQVELLFKEWKSHNRLKGFVTGEKAIAEGLVWTSLLS
                     LVMKRRVAQSVMSGALSMLKASKNSATWWLPLLEAVAHRALTEIRERLEWAADYLAKNA
                     CRTKQRKSIQNRTLEGVLNGLAA"
                     /name="IS4-like element ISApu1 family transposase"
     gene            <30225..>32828
                     /locus_tag="KZX48_RS25985"
                     /old_locus_tag="KZX48_25975"
                     /pseudo=""
     CDS             <30225..>32828
                     /locus_tag="KZX48_RS25985"
                     /old_locus_tag="KZX48_25975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611787.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn3 family transposase"
                     /name="Tn3-like element Tn3 family transposase"
     gene            32930..33109
                     /locus_tag="KZX48_RS25990"
                     /old_locus_tag="KZX48_25980"
     CDS             32930..33109
                     /locus_tag="KZX48_RS25990"
                     /old_locus_tag="KZX48_25980"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_232038188.1"
                     /translation="MASLLEVSDWERIARQELERRATSIVQALDDATLEAIAAGTLDML
                     AMCRQVADEIHQAA"
                     /name="hypothetical protein"
     gene            33264..33902
                     /gene="parA"
                     /locus_tag="KZX48_RS25995"
                     /old_locus_tag="KZX48_25985"
     CDS             33264..33902
                     /gene="parA"
                     /locus_tag="KZX48_RS25995"
                     /old_locus_tag="KZX48_25985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008166580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family partition ATPase"
                     /protein_id="WP_033996216.1"
                     /translation="MQVIAVLNQKGGAGKTTIATHLARALQLDGADVLLVDSDPQGSAR
                     DWAAVREDQPVPVVGIDRPTIERDLKSVARKDFVVIDGAPQAHDLAVSAMKSADCVLIP
                     VQPSPYDIWATSDLVDLVKQRIELTDGKLKAAFVVSRAIKGTKIGAEVSEALAGYGLPI
                     LQTRITQRVIYPSSAASGTTAIDQEPTSEAAEEIRALAEEVRRFLNCTI"
                     /name="parA"
     gene            33945..34145
                     /locus_tag="KZX48_RS26000"
                     /old_locus_tag="KZX48_25990"
     CDS             33945..34145
                     /locus_tag="KZX48_RS26000"
                     /old_locus_tag="KZX48_25990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017154717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid partition protein ParG"
                     /protein_id="WP_008166578.1"
                     /translation="MKAGRPSAAKAGPTLSDLADKAATVRVNFDLDRAEHTKLKIYAAK
                     TGRSITDILRELVRSLDEKSD"
                     /name="plasmid partition protein ParG"
     gene            34179..34565
                     /gene="parC"
                     /locus_tag="KZX48_RS26005"
                     /old_locus_tag="KZX48_25995"
     CDS             34179..34565
                     /gene="parC"
                     /locus_tag="KZX48_RS26005"
                     /old_locus_tag="KZX48_25995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020750543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParC family partition-associated protein"
                     /protein_id="WP_011270177.1"
                     /translation="MDYSPYIFDLAKFNNVDEIRRVGYKVMVEMEPLSLEVLPPSHFKA
                     FAKNAPHEIKGAVIENTERGLVIVLHVGNERRILGQYRGGIRFFRSFDGAAAVLRQHGV
                     LHWTANAKGWIPRTLEAKERSSDG"
                     /name="parC"
     ARG             complement(22784..23661)
                     /name="blaKPC-2"
                     /gene="blaKPC-2"
                     /gene_name="carbapenem-hydrolyzing class A beta-lactamase
                     KPC-2"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(23884..24365)
                     /name="TEM-196"
                     /gene="TEM-196"
                     /gene_name="TEM beta-lactamase"
                     /tool="rgi"
                     /drug_class="monobactam; cephalosporin; penam; penem"
                     /identity="99.38"
                     /coverage="55.94"
     Typing          2..1377
                     /name="IncP"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          19013..19572
                     /name="IncU"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atgggacagg cacagctacg acttttcagc ccagccgatg aggcgggttg ctatcacgac
       61 acagcccggc agggcttttt ctcgttgctc atggcgacgt gcgagggcag cggcaagaag
      121 caggacagtt accggctgtc acagatgccc gtggtgctct ccatgctcga ccacagccgg
      181 gatacctggc tgtctcaggc tgagttcatc aagcccaatc gccgcgtggt caacttggcc
      241 cgcatcggct tgctgttcgc cgatctggac acctaccgcg agccgtgggc gcaggggcgc
      301 agccccgagc aactggccgc cgctgtcatg ttccgctgct acgacgaagg cgtgccgccg
      361 ccgtcgatcc tcgttttctc tggccgtggc gtgcaagcaa agtggctgct ggatggcacc
      421 ttgccgcgtc aggcgctgcc acgctggaat gcctgccagc gttacctgat cgaccgtctg
      481 gccgggctgg gcgctgatcc agcggccaag gatgcaagcc gcgtgctgcg gctggtcaat
      541 acggtgaaca gcaagagcgg cgaggtttgc cgcgtcatcc acgttgagca aggcccggac
      601 ggcgagccga tccggtacaa cttcgagtat ctggccgagg cgctactgcc ggtggcccgc
      661 tgggacatcg aggccgaccg caaggcccgc gccgaccgtc gccagttcaa gctgctgccg
      721 ggcggccaaa ccggcaacct gcgcacgctc aacgggcggc aactggcgtg ggatcgtctg
      781 gaggacttgc gcacgctggc cgcgctgcgc ggcggcgtgg ccgagggcga gcggatgcag
      841 cacctgtttt ggcggctgaa tttcctgctg ctgtcaggtg cgacgcacac cggccagatg
      901 taccacgagg ccgccgcgct ggcccgtgag cttgacccac ggtggaacta ccgcagcgcc
      961 gagcttatga cgctgtacgc caaggccaag gcccacgaag ccggggaaaa ggtggagttc
     1021 ggcggcaagc agtttgcgcc gctctacacg cccaagaacg acacgcttat cagcctgttt
     1081 cacatcaccg acgacgagca gcgcaagctg cgcacgctca tcagccggga catggccgca
     1141 gagcgccaca gcgagcgcga gaaagcccgc agacgtgccg ctggggctgt cgatcgtgct
     1201 tcctatctgg aagcagccag cgccaagcag gcgcaggctt tggccctcaa ggcgcagggt
     1261 ctgagcgtgc gggccattgc tgcacagatg ggcattagca agaccgctgc cgggcgctac
     1321 atcgcagagc cgggagagtg tcccaagtcc atgcgtatta caggcgggga gggctgatcg
     1381 tgaggtgttc aaagtccgtc cgtattacta atggcggagc cttccgggcg ggtgtcccaa
     1441 gtccatgcgt attactaatg gcgaagccta cgcccggcgc gtagcgcctg cctttgagta
     1501 gcgcctgcct ttgagtagcg cctgcctttg agtagcgcct gcctttgagt agcgcctgcc
     1561 tttgagtagc gcctgccttt gagtagcgcc tgcctttgag tagcgcctgc ctttgagtag
     1621 cgcctgaacg gcgcggcccc ctcgtccagt tcatcgggtg gctgtcatga gtcgcgcccg
     1681 tcgatccttt ccgcccgcgc tgctggattc gttgcgggca atgacggtgc aggaaacgct
     1741 agaccggctg ggcctgtact ggaaacgtga acctggcttt gtgccggtga aggaggggtt
     1801 tggggagcaa tggaaccaaa aaccaacgta agccctacca acgcttttcg gtgtcttctt
     1861 cccaggcgcc catctcgaca aaacagttgc gcatgtcggc ctcctggctg atctcggtca
     1921 gcaggtcatg cacgctcttg tccagctcat cgtcgctccg atacggaatg gtcaactcat
     1981 agtggccggc atccagccgc ttcatgccat agggctccag gcagtagcgc tcaatgttct
     2041 ccgtggcccg cttccggccg cgcacgaact tgctgttatt caccaccgcg aggcgcaggg
     2101 tgacggtggc cacccgctcg gcggcgggcg gctctgccgg cgacgcggcc gaaggctgct
     2161 ggtcgcgtga cctggcgctc ttctggtacg cgccgatctc gacaccacgg tggcgcaggt
     2221 agctgtacag cgtgctcttg gagatgtgca gcttctcgcc gatcgcgctg acgctcaggc
     2281 gaccttcgcg gtagagggtt tcggccgcca tggcggtggc ctcagccttg gctggcaggc
     2341 ccttgggacg gccaccgatc cggccacgcg cccgtgcggc cgacagaccc gcctgagtcc
     2401 gctcgcggat cagctcgcgc tcgaactccg ccagcgaggc gaacaggttg aacaccaggc
     2461 ggccttgggc gtgggtggtg tcgatggggt cattcaggct ctgtaagccg accttgcgct
     2521 ctgccagctc gccgaccaac tcgggctccg tttgggaaac ggcaaatatt gtacgttaag
     2581 gttgtttttt gtactggctg atatcaaccg gccgcaaagg tcgatacttc ccttctgcca
     2641 gttttttatt gtttctccag atataatctc ccgtcagatt aatgtgctcc cagcccaacg
     2701 gagacaagtg tgacagcaat tgctcattga gatgtagccc cttcctcttc agcaggttaa
     2761 cggcgttctc tatatatacg gtattccaca atgtgatcgc ggcggtgatc agcgtcagtc
     2821 cactggcccg gtaactctgg ttttccagac ctcgatccct tatttcgccc agacgatgca
     2881 tgaaaacggc tctggcaagg gcattccggg cttccccttt gttcagacct gcctgaactc
     2941 tgcgacgcag tgaaggatcg cgaaaccagt ccagcataaa cagtgttcgc tcaatgcggc
     3001 cgatttccct cagtgccttg gcaagcccat tctgtttcgg ataactggcc agctttttca
     3061 gcatcagaga agcggtcaca gttccctgct ttattgaggt cgccagcctc agaatttcat
     3121 tccagtgggt ttctatctct ttgatattca gttgagttgt ggaaataatt gactgtagag
     3181 ccggatattt atcagccttc ccctgaataa acaaccgctt gtcatgaaga tcccggatcc
     3241 tgggtgcaaa agcgaacccc agcagatgca tcagcgcaaa aacatgctcc gtgaaacctg
     3301 ccgtatcggt gtaatgttcc gtgatttcaa gatcactttc gtgatacagc aggccatcaa
     3361 gtacgtgggt ggaatcacga acacggctga tcactttggt gtaaaacgga ctgtattggt
     3421 cagaaatgtg cgtataaaac tgcacccccg gctcctgacc gtacttcagg ttgacctgac
     3481 cggcatagcg gccatggctg ccaacccgaa aattctgacc gtcagaagat gaggttgaac
     3541 cgtctcccca taatgccgcc agcggacgtg acttctgggc attaaccagt tcagccagtg
     3601 cagcagagta cgtttcatcg cggatatacc atgcctgcat gttttccagc gaagcccgcg
     3661 tggttcccgg acaggactct gccattttgg tcagccccag attgatgccg tccgccagga
     3721 tggtggtaag cagcaaacgg ttatcctgcg ggcgggtaag cgggttcttc agatgggtaa
     3781 aatgtcgcga gaaggctgtc catctctcaa cttcatccag tatttctgta atttttgggt
     3841 gtggcaacat gttgtaaatc aggtcggcca gtggtgatat tgtggaagga acgctgttat
     3901 ccagcggggt gatctttaga cctttatctg aaatatccac atcgggaaga tccccggtaa
     3961 cggccattgc gttaacttcc tccaggcggg aggccagcag cgtcagcctt gccttaaggt
     4021 aagcttcgca atctgtttcg acaggtatat ttaactgatt attatttaat aacttttcga
     4081 aattatctcc tggcataaga tagtcatcga agtttttgta gcgccgggaa ccccggatcc
     4141 agatatcacc ggcccgcagc gcccccttca gctcgttcat tgcgcaaatt tcatagtatt
     4201 gccggtcaat acctgagggg gtgatcacca tctttttcca gctctcaggg atgaaatcca
     4261 gtgacgctga tgagggaacc tttcttagct gcttacgata catttcacgg atagtatcga
     4321 gggcatcatt aagagataag gcggccggag tggccctcag ttgcagggcc gataacaacc
     4381 gggacgaata tttgcgcagc gtgctgaatt tttcggtaat aagatgaagc ggttcgaaat
     4441 tatccttacg tgcaaggagc cgggtttcct ccaagctggc ggcaaaatct tcccacggta
     4501 atatctgttc aacagcagac agaggatctt cgcctgcgtt gcgtgcatcc aagatagcct
     4561 gtccaacgga aacatactgc cgtaatttct gctgtatcag cttgcccgtt ttctgaaggc
     4621 gttcggcctg ctgacgtttt gcccggctga acatactgcc cagtatgcgt tcatgcagtt
     4681 ctataatttc atcaatgatt gtggctctgg cctcagtcag tacacagacc atcgttgcgt
     4741 atcgacgagc aggggaaaaa tcagctaaat cccggctgct cattttgcgg ccttcccgcg
     4801 ccagtttcag cagccggttc tgatgaactg ttttatccac gccttccggt agcgccagtg
     4861 cttcaatggc gttaaggcgg tcgatatgtt gcaggacatt ctttccattg atctttcccg
     4921 gaggctgaag caaccacgtc aaacgggaga tttgtttttc agttgtcacc agtagcgcat
     4981 caagcgctga tttatgcgtg atactaagat gcgcattcaa cgtggtgtaa accgctttat
     5041 cacccagtgt cattgcttca gcacaggtac gttccacaac atcaatacca ggaataataa
     5101 ttcgctgttg atgcagacgc ttcagtaatt cctcggcgat aagtatgccc cgatcggtcc
     5161 tggtagacag agggagcaga tgctggatgc attctttctg aagtgcccca ttaaaggctt
     5221 tcagttccag ataccgatac agttccccca ggtgctcgcg ccgggtggta tcacggccgg
     5281 aaatatattc ctgccagagt tctgctgaaa gtttaaggcg gttgccgatg actctgagca
     5341 attctgccgg tggagacgat tttttatccg gagcaaaccc gatatttttc agatagcaaa
     5401 gaaggacggc gaaaccaaac cggctggccg gtttacgatg agcattaata aatgccagat
     5461 cctgctcact gaaataggcc attcgggtca gcgttaactc atcgtccggt aatgccagta
     5521 atgattctct ttccgacaga gaaagaatct gcctccttgc catatagttt tcctcgtaaa
     5581 ttattcagta cggtattttt aacaaaacca gatatcgcat aagggtacac cccgacgcca
     5641 tactcaaaac gtgacggcac acgatgaatg acataaccta tatgcgatag aattaatgca
     5701 ataacctaaa tgcgataacg tggtgaaaaa atgttcatca gagcttattt aagggcatcg
     5761 acggaagatc agttcgccga tcgggcaaaa gagatgctgg agcagttcgt ccaggagcgg
     5821 gggcataaaa tcgccagcta ctatcgggag aacatcagcg gtacaaaact tgaccgtccg
     5881 gagctgggcc gcttactgat ggacagtcac cgtaatgata ttttgctggt cgagcagata
     5941 gaccgcctga cccgtctcag caacagtgac tggatgacgc tgaaaaagca gatagaacaa
     6001 cacgagttgc ggattgtcag tctggatgtt cccacctcat ggcaggcgct gtcagagaaa
     6061 gatccttcac aggctgaccc gataacccgc gctgtcatta ctgccatcaa caatatgttg
     6121 attgatctga tggctgcaat gtcgcacaag gactggctga gtcgtcgcca gcgacagcag
     6181 cagggaatta agcgtgctca ttctctgggg aaataccggg gcaaacaggc agaccaggaa
     6241 cgacaccaga aggtgttgta ctaccgacag gttaagaaac tcagtatacg ggagacagca
     6301 gaagcaaccg gctacagttc ttctcaggtt tgtcggatac aggcgcttaa taaaatcacc
     6361 ggtactgatt gaatcagctt taacctggat caattcccgc ctatacaacg tactatcaaa
     6421 cttatcatct gaaatgctat gctcgtcgtt atgtcaaaaa tggcataacg aatcagagag
     6481 gaatgcatgt catcagtttc aaaaaggaat ggaaaaggtt ttttctcagg cgcggtaatt
     6541 ggggctttag gagggctgat tgggctcggt ggggctgagt ttcgccttcc cgtcctgatc
     6601 ggtagtttca aaatacccac cctggaagcc gtcatcttta acaaagcaat gagcctcgct
     6661 gttgtcgcta tcgctctaat tttccgcaca aaatcgatag cccccgatca gttggtagag
     6721 catcttgata ttgtcatgaa tttactggcg ggaagtctta ttggggcatg gtgggccgca
     6781 ggccgcgcca ttaagatgtc cagaatctgg ctggacagaa tcattctgat cctccttgtt
     6841 ttactgtcgt tcgtcatgtt ctcagaagca tggctaccac tacacagtat ttccggcggg
     6901 ttatttcaac ccggtattgc caccattatt gcaggtgtga tttcagggtt ctttatcggg
     6961 atagttgcag cattgctcgg tgtggctggc ggtgagcttc tgatccccac aatcgttatc
     7021 ctgttcgggg ttgacatcaa actggccgga agcctgtcat tgatgattag cctgcccaca
     7081 atgattgttg gtttttcccg ttatacaaat gcagatgctt tccagattct gaagaaagaa
     7141 aggccactgt ttgtatggat ggtcatcgga tctgtgattg gtgcggcaat tggcggactt
     7201 ctggtcggcc tgttcccggt taaggtactt atgactttac ttggggtgat ccttcttatc
     7261 tccgccatca aaacgttcaa acacacccgg caaaaataat ttcgagaaag gtatcaggat
     7321 gaataaaaaa gcgcttatat ctgattttat tttggtcaga ccccgaattt acattaatga
     7381 caacatctcg ctggggccgg gtaaaattga tctattgcgc gctatagatg ggtttcactc
     7441 cctgtcagcc gccgcaaaag atctgggtat accctacaaa agggcttggc tcctgattga
     7501 tacgttaaac aaagggatag gtaagcccgt ggtcatcacg tcaacaggcg gcagcaaagg
     7561 tggaggctcg gttttgacac cacttggtca gaatctactt agctggtacg acaaagcaga
     7621 agccaacctt aacgaacaat cacagcagga cttgcaggat ctcgaaaaaa ttatcttcgg
     7681 tgagaaataa cccattcggc tcggtctttg atcgggccat gaccgtacaa aaaatcatct
     7741 taacgtacaa tattgtccgt ttcccaaacg gagcccaact cgaccaggtg cttgagggaa
     7801 cgcccaaggc gatccagctt ccagatcacc acggcatcac ccggccgcac gttggccagc
     7861 agtttgtcca actccggccg ggcgcttttc gcgccgctgg cgatgtcttg gtagatgcgt
     7921 tcgcacccgg cctgtttcag ggcatcgact tgtaggtcgg ctttctgatc ccgagtgctc
     7981 actcgcgcat aaccgatctt catcaaaagt actgtttact cgactacgtt agtaatagtt
     8041 gaactttgat taagcgtacc agttatttga accgtagcgc ggggagctta acgaaccgag
     8101 ccattcctcg atagagttcg gcaaaacctt cgttttgtcg aaccattgca tcgccctttg
     8161 tgattggcgt ataaacacac aaacacctat tagcggagaa cgctatgaat accattcgct
     8221 ggaatgtcgc cgtctcggcc gacaccgacc agtcgcttcg gatgtttctg gccagccagg
     8281 gcggcggccg taagggcgac ctgtcgcgct tcatcgaaga agcggtacgg gcacacatcc
     8341 tggagctgag cgctgagcag gccaaggccg ctaacgccca tctgagtgag gcagaattga
     8401 ccaacgcggt tgacgaagcg ctcgactggg cacgtaagcg ctgatgcggg tcgtgttgga
     8461 taccaacatc ctgttcagcg ccctgatctc gccacatggc gcgcccgatg cgatctaccg
     8521 tgcctggcgg gcggcgcgtt tcgaggtggt gacctcgcgg atgcaactcg atgaaattcg
     8581 tcgagccagc cgctatccca agcttcaggc catcctacag cccgccaagg tgggcgccat
     8641 gatcaataac ctgcaacggg ctgtggtact ggagcgcctg accatcgagg tcgaagccga
     8701 tgatccggat gactcgtttt tgctggccat ggccttggcg ggcgatgcgg actacctggt
     8761 aaccggtgat cgccgcgccg gcctgctgca acgcgggcac atcgaacgca cgcggatcgt
     8821 cacgcccgcc gtgttctgcg tcgaggtgct gtgatcaatg ccggtcggtt ttctgactca
     8881 agagcaacgc gacggttttg gccgctatgt tgattcgccc agccgtgaag agctggaacg
     8941 ttacttccac ctgagcgatg aagaccgtga agccatccag gtgctgcggg gtaaccataa
     9001 ccgtctgggt tatgccgttc tgctgaccac cgtccgcttc gttggcgttc tgccggacaa
     9061 gcccgccgcc gtgccggtgg aagtcctgca ggtgctttgc cgacaactgg cgattccaga
     9121 ccccgactgc ctccagcgct atagcgatca tcgccgctgg atacatgcca ccgatattca
     9181 gaaccgcttt ggctatcgtc atttcaccga tccgggcatc ggctttcgct tgagccgctg
     9241 gctgtatgcc ctctgctgga cgggcaccga ccggccggga gtgctgtttg agcgagccac
     9301 ctcgtggctg ttcacacaga aagtcctcct gcctggtgtg tctcaactag agcgctttat
     9361 cgcccagttg cgcagtcggg tcgaagaacg cctctggttt acgctgggcc gcagcgtgac
     9421 tgaggaacag cgattgcaac tgcaagactt gctgacggtg gccgaaggca accgcagctc
     9481 ccggctggat caattgcgct ccggcccggt catggtcagt ggccccgcgt tgattcgggc
     9541 actgcgccgg ctcgatgacg tgcgcggcat cggcatcacc ttgccggcgg cggcgcacat
     9601 ccctcccagc cgtatcgccg ccctggcccg cttcgccaac acggccaagg tcaccgcgat
     9661 taatcggctg ccggcgtcgc ggcggatggc gacactggtg gccttcgcac tctgcctgga
     9721 ggcgactgcg cacgacgacg cactggaagt cctggaggcc ttgctgcgcg acctgttcag
     9781 caacgcggag aaggccgaca agaaagcccg catgcgcagc ctgaaagacc tggatcggtc
     9841 ggccgcgacg ctcgccgccg cgtgcaaggt cgtgctggac agctcgatca gcgatgacaa
     9901 cgtgcgcgcc cggctgttca acgacctgcc gaggaccacc ctggaaaagg ccctggaaga
     9961 ggtcaacgcg ctgatccgcc cggtagatga cgtctatttt cttgcattgg aagcgcgcta
    10021 ccgcagcgtg cgccgcttcc tgcccgacct gctcaagcac atccgcttcg gcttcagccc
    10081 ggccggcaag ggcgtggcgg ctagtctgga gtggctgcaa ctgaacctgc cgcgccggaa
    10141 gccagaggat gacgcgccgc aggagatcgt ggccaaggct tggcagaagc acatcacccg
    10201 cgaagatggc tccctcgaca tgggtgccta tgtgttctgc acgctcgatg cgctgcgcac
    10261 ggccctgcgc cgccacgatg tcttcgtctc gcccagttgg cgctatgccg acccgcgtct
    10321 tggcctgctc gacggtgccg aatggctggc ggcgcgaccg atcatctgcc ggtcactggg
    10381 cctgaccatc gacgccaaaa ccaccctgga cgccttgtcc gtcgagctgg atgcaacctg
    10441 gctggcagta gccgcgcgcc tgcccgacaa cccggcgatt caactgagcg agaacaccga
    10501 gggcaagacc gaactgtcgc tcggggcgct ggacaagctg gacgagccct gctcgttgct
    10561 gcaactgcgg gcggccgtgt ctgacctgat gccgcgtgtc gatctgccgg aaatcctctt
    10621 ggaaatcgcc gcccgcactg gcttttccga ggccttcacc catgtctccg aacgcaatgc
    10681 acgcgccgac aacctggtca ccagcctctg cgcggtgctg ttgggcgggg cctgcaacac
    10741 cggcctggag cccttgatcc gcaccgacaa cccggcgctg cgccgtgacc ggctgtcctg
    10801 ggtcagccag aattatatcc gcgacgacac cctgtcagcg gctaacgcca tcctggtcgg
    10861 agcgcaaagc caactggaac tggcccaagt ctggggtggc ggcgaggtcg cctccgccga
    10921 tggcatgcgc ttcgtcgtac cggtgcgcac cgtgcatgcc ggccccaatc cgaagtattt
    10981 cggcaccggc cggggtgtca cctggtacaa cctgatttcc gaccaattct ccggcctcaa
    11041 cgccatcacc gtgcccggca cgctgcgcga cagcctggtg ttgctggcgg tcgtgctgga
    11101 acagcagacc gagttgcagc cgacgcaaat catgaccgac accggggcct acagcgatgt
    11161 ggtgttcggg ctcttccgcc tacttggcta ccacttcagt ccgcggctgg ccgatgtcgg
    11221 cggtacccgc ttctggcgca cgcgcccgga cgcggactac ggcaagctca acgggctggc
    11281 ccgccagtcg gtcaaactcg acctgatcgc cgagcactgg gacgacctgc tgcgcctggc
    11341 cggctcgctc aaactcggcc gggtgccggc gactggcatc atgcgcacgc tgcaaacggg
    11401 agatagaccc acccggctgg cccaggcgct ggccgaattc gggcggatcg aaaagactct
    11461 gcacacgttg acctatatcg acgacgagtc caagcgccgc gccaccctga cccagttgaa
    11521 ccgaggcgaa ggccggcaca gcctggcccg cgccgtgttc cacggcaaac gcggcgagct
    11581 ccgccagcgc taccgcgaag gccaggaaga ccagctcggt gctctgggcc tggtggtgaa
    11641 catcatcgtg ctgtggaaca ccctctacat gacggcggcc gtggaacggc tcaagcagca
    11701 cggctatcca gtgctggaag aggatttggc ccggctatcg ccgctgatct acgagcacat
    11761 caacatgctc gggcggtatt cctttgcggt accggaagaa gttgcgcgcg gcgagctgcg
    11821 gccactgcgt aatccagacg acgacctgtg atccccctaa acgctatgag caacacccaa
    11881 gctgctgctg gatcggcggg cacttcaccg agccgaacga acagaaaacg cagcaatccc
    11941 ctgggttggg gcgcagcagc gccttgcagt tgctgcactc gtaatagaac tggcaggcgt
    12001 ccgtgggcat ggtttccggc ttggcgaagc cgcagcgcgg gcaagtcagc acggactcaa
    12061 ggacaatggc gctcatcgtg acctcacttc tgcactgtgg aggggtatcc cgcgttcgcg
    12121 gtcgcctcag tcagtgcctc gggctgggcc ttatcgggat cgtaggtgac ggtcgccgtc
    12181 ttctggtcga aattgacctg gacgtcactc acgccggaca ccttctccag cgacttcttg
    12241 accgtgatcg gacagagtcc gcacgtcatg ttctgcacgt cgagcgtgac ggttttcggg
    12301 ggagccgcca gcgccacgaa gggcaaggcg aaaagcacgg cgatcagcag tttgcgcatg
    12361 gttaatctcc ttcagtagaa cagcggggcg agccacggca cggccaatag gccgagcagc
    12421 agcacgctga cgatccagaa cacgagtcgc tgtcgcacga gcgtgcgcgg atcggcgcag
    12481 ggtgtacctg gcgtacaaac ctgtggcacc aggtagagct tgcggaatgc caatcccagg
    12541 aacagtagag tcaacccgat gaagaggggg cgtagtggct ccatcatggg gtcacctcag
    12601 aaaacggaat ctatggtcac tcccgttttt gcaacaccga ttttgacgat aaattggctt
    12661 gcttgaatct atccggcgtc tgaatgggat tttattcccg cgcctcgatg agttccgcgc
    12721 ctgatgaacc tccagaaaat atacggcttc aatgagcctt tccgttttac aggttcctca
    12781 acaggccggt gggccgttag tatcatcaat atcagtattc gcaaaaccag atcagtgatt
    12841 ctttaaaccg gtgtatttct gccgttatgc tacataagtt tgctgtcgtg ccgttagggc
    12901 ccaggctatt ctggccagct tgtttgccag agcacaagtg acgacaaagt tgcttttcct
    12961 acacagtaga tccctgaccc aatcggccaa tttgccagac tggtgttcca gtttttgtat
    13021 gaataccctg gcacattgaa ccaacaaagt tcggatcttt ttgttacctc gcttactaat
    13081 tcccagcaat gtcgtccgac ctcccgtgct gtactgtcga ggcactagcc ctgttgccgc
    13141 cgcaaagtca cgactgctgg cgtactgctt cccgtcgcca atctcagttg aaatagtact
    13201 cgctgtcagt gttccgacgc agggaatgct cagcaagcgc tgtccaatct catcttcgtc
    13261 caactttcgt ttcaactggg attccaaatc tttaatctgc tcaacaagat agtgataatg
    13321 ctgttgtaat ttcagcaata actggctgag gtatagaggc aaactattgt cctcaagaag
    13381 ggtactcagt cggctaataa cggcagctcc tcgtggaacg ctgatgccaa attccagcag
    13441 aaaagcatgc atctgattgg ttgtttttac cttatcctga accaaggatt cacggacacg
    13501 atgcagcgca cgcattgcct gctgagattc agttctgggc tgtacaaaac gcatagacgg
    13561 acgcgatgca gcttcacaaa tagcttcggc gtcgacaaag tcgtttttgt tacttttaac
    13621 gaatggacgg acaaattgtg gtgatatcag cttaggaaaa tgccccaact cttccaactt
    13681 gcgtgccata aagtgagagc caccacaggc ttccattgcg atggttgtag cggggcatgt
    13741 cgccaaaaat tcgattaact ttggccgtgt aaatttttta cggtaaacag ccttgccgcg
    13801 acgatcttgg caatgaatat ggaaagagtt tttacccaga tcgataccaa tgagcgcaat
    13861 gttttccatg atagttctcc gaatgaaagc ctatcctcag catagtaccg ggaaggaggg
    13921 agtgaccatc tcattaaaaa tcgtacggta agccgctggc atggtctagc ttctcgcaaa
    13981 cgatcgtttt tgagaggctt caatgagaat cagatccgcg ctagtgctgg tatggcatgt
    14041 tgctttctcg aaaaccactc tcatattgca cggctgaaac agccgagttt cgagaaccac
    14101 gaaaatgctg tttctagggg ttggcagctt gcgcaaagcc gcgcagttgc tgggtatcgg
    14161 atctcttaac gtgctttaat ttccgaattc tgaagcgacc cctatggtgt ctttggtgca
    14221 ttggttagga taaaacagct tcaagacttc ctgatcaagc tctgcttctg tttgttcgtc
    14281 tgctggcaat gttgcattgc tcttaccaat cataaaacct aaccgccgtt tcttgtcctt
    14341 ctgttcgtgc atgatgtacc tccccagcac agccagatcc tgcatagagt ttagtatacg
    14401 ttacagtgtg acttactctg cagtagcctt cggcctgtgc ttcgctgtgg tgtagtatcc
    14461 ccaaaactcc gtctaatacc tgatattggt taatggcaca cataacaact ttttttggta
    14521 gatctattga caagtttttt tggtatagta aaactgtaag agattataaa taaaagaaaa
    14581 gcccgcgttc tctgattagt ttggcgacag tgagagaacg gggcattaca gaaaggatac
    14641 tgctaaatgt tcaatataga aaataacaga gagatattaa aaagtcaaat acctttaaag
    14701 ccatatgcta caaatgattt agagtttgga ttgactattc aaaataagaa taaagcttta
    14761 gatatgcttt atttacaagt aaatcacccg ttgtatcttc atacaatgat atttgattta
    14821 gacaaagaaa actgctttta tgagtttgaa aatgctcatt tgcccatccc gtcttttata
    14881 acaaaatcac cagactctgg tagatgtcat tacggttata tgcttaatgc tccgatctca
    14941 tcaacagaga aaagcagaca gaagcctgtc aagtttgcca gagcattata ttacaatatg
    15001 gctactcgtc ttggtgctga tcttggctat gcgggactga ttactaaaaa cccactgcat
    15061 agccattggt cgccgttctg gtctggtgct gatttatacg aacttaatga tttagctgat
    15121 tgttttgatg atttagaaga ccccaaaaaa cgagaaaata cggggcttgc ttttggtcgt
    15181 aatgttgaaa tgttcgacac aataaggcag tgggcttata aaaatgtgct aaaatatcag
    15241 agtgaaagct catttaatga tttccacaat gaactattgc taaagtgtca aatgcataat
    15301 gcatatttaa atgctgatga tttattgcca tataatgaga taaaagccac agcaaaaagc
    15361 attgcaaagt tttgttggaa agaattcagc gaagaaaaac tcaacaagat acagagtaaa
    15421 aaacagtctt accgtggaaa gaaaaacaaa ggaatagtaa aaagtaaaac tcgtaagttt
    15481 ttggaggcca taaaatgaaa gttaaaaata gaaaaagaga acttactgca aaagagtatg
    15541 ctgaacagta tgagattagc gttagaacag taaaaagata tttctctcaa gatcgtgaag
    15601 actatgagaa agaagcaaaa caaagacgat taaaagcctt tgtattacgt gaaagcggga
    15661 tgaaatgggc agaggttggt attgctcttg gaactacaaa acatggtgct atagctcttt
    15721 ataaacgtta tcaacaaata gacgcaccaa caacaaaaga ggcttaaagc ctcttttatc
    15781 gcggtttaaa acctcttggt tttaaatgct gatcgtcttc ctgctgtagt tgtgttggtg
    15841 ttgtttcatt tcttggtttt tcttttttaa gggtttcttt taacttcgat ttaaatctat
    15901 tttcattcat actcaaacct aaaggttttt tctttatttc ttctttaact attttttctt
    15961 tattctttgg ctgaataaca ggttttttta ttccaagttt atctcttatc tcttcgatct
    16021 tagttgctcg actattgaaa cggctaccgc tcttgagtct aaatgaatag gtggctgcgt
    16081 ttgctgtttc tgcatgatca agtatcctac caatagaacc gctatcagat ttatcacgcc
    16141 aactattgag gccattttta ttataagttt tgattggttc tttattgtat tgttttttaa
    16201 ctctgttgag tatttgtgca gctttttgtg ttgttcttct aactttatgg cttgctggtc
    16261 tattatattt ttcgctgagt ttaaagctgt tgttgttgct tctaatgagt tgttcaccct
    16321 cgtaagtgtc tgttgtgtct ggtttaatgc cgtgctgact gactccgata gtatcatcat
    16381 cgattctgtc aacggctcta ctgtcattga aatctggttc agtaggtgat cgtctaatac
    16441 tattttcgtc atctgttttt cttgctgcga atcttctaac gagttcatca tctctatttt
    16501 tgtcatatat caccttgttt tttatagtgt tccaactgta ttttttacct aactgcgaac
    16561 ctttgaaggc cacatctccc acactgaatg aaacccccgc cacgttgcca gtgctggcaa
    16621 cattgaacct tggttcaatg cctacggcct gcagacgttc tacgaacgta gacaaatcag
    16681 gcttaccgac taaagctgct tgtagtgcgt tctgtagcac taaacgggct ggtttctcac
    16741 ctgtcctcaa ggcttgctcg atctctgctt tggttggtgc tgatacgtct gatttttggc
    16801 cttttaagcc atccgtgatg gttaagccgt gctttatctc caaacgttca caagctgcta
    16861 ttgtgttaaa tgctgagtgc tgcccaagcc atactgaacc gtctaaaccg actctatttg
    16921 ctactatatg gatatggtct tgatctgtat cgttatgacg cacacaaata tattgatgtt
    16981 tttctatatt aatattcatt tctttcaaat agtcttttgc tatctcttgc cattgttcat
    17041 ctgttaaatg ttcattcttg ggaagagata aaaaagcgtg aaaaactggt ttttttatat
    17101 cttgtctaaa gctgcttaca gttttaaact catcagttaa atcactaaca ttattataat
    17161 cacttgccat gttgctacat atgaaatcgt gatcatcttt taatatatac tcaactctat
    17221 ttttaaatga tctacctgtt ttagctacgt ttcctttcat actgtataaa cctcgcaagc
    17281 ttttaatatt cttttcataa gttgctttat ggcaaagtta gcttctgctg ctaaagattg
    17341 tttaaagtct tcgttggtat ttagtttttt agcaatctga tttatattat taccttgatg
    17401 ctgtatttcc ttaaacaagg attgttcaaa atccggcatt tttcttttaa caataggttc
    17461 agagtttaaa atctcttttc taatgtaatg gcctctctca aggccggagg cttccacaag
    17521 ttcttttaaa tagtcaaact ctgctttgtt tactctaaac tgtatagata tatctctacg
    17581 tacttcgtga tttaaaccct tgcggcctct ttttctatct gtatccatat ttaccacctc
    17641 cataaacata atctttcatt gctttgatat aatcttcatc tttttgattt ttcaaagcat
    17701 caataagatc ttgagtttta ttttctttaa tatagcgata agctacaaaa taacataaat
    17761 cttgttcatc tttatttgct tcaagaaatg ctgtattttc ttcatttggg tctatataat
    17821 aaaaatatct tgctaatagt tctagcaagg actgatctat atcattctca ttcattttaa
    17881 acactcctat atatatttat aacattcaat gtaaaactgt atggtttacc gcttcccctt
    17941 gataggggaa taagcggaag ggtagatctt tttcaacctt gcgagtgaaa cgagacaagg
    18001 caatccgata ggattgggta aaatagcgga tacgctatta caccttgcct cagtttccga
    18061 aagctaaaaa ataaaagctg aactcaactt atatttaaat aaataaccga tctaaaaaac
    18121 tagtcaatag cggctacata aataaataca ctgcaagaca aataaaatgc aaataaaaaa
    18181 tagggtaaat aatatattgt cttgatgggt agctgtgcgt aataggtagc tttgcgtaaa
    18241 aaatgctgct gctacgtgaa atctggaaaa gttcgtgacc atcagatcac cagattttaa
    18301 ggaatggggt ttgatcggcg gcgacagaaa cgagtaaaac ttgcttttgc tcgtttgctg
    18361 gcgtctatgg gtttaaaatg ctcataaaat caacagacta tagtatatat tagtatatac
    18421 tgcatcgagg gttggccttc tctcaccgtt ccgggtcggt ttgttctcaa gtggtgaaga
    18481 tggccagctc tcccctaccc tctacagctt caattttttg aacaggtcat cagaaccgga
    18541 ggccgtgaaa acgtctgtac cagcttctga gcgttctatg gtggggacgg tagagaaaac
    18601 ggacaaaatc gtacgctaag catgcggcct gtcaggttga ggccatagag tttgacgttt
    18661 aggcgtcaga taatgcagaa agcggcccta gtctgacgcg atgccagtga gccgactgac
    18721 gcccagttga ggtatagcct agattgacat gcgcgatgca acccttaact tgcttgcacc
    18781 tatcgtttcc atgctagctt tatcgtaacg ctaaggaagc tctgaaaaag cccatgtttc
    18841 gcgaaatcac cgctctgtaa cccgcatggt tgctgggatg catttctcga gcgggggctt
    18901 tttcagacct tccttagctt agcgtacgat tttttccgaa ttctgcggtt ccccctggaa
    18961 gacctacgca agttgggcca gctcagaggt ggaatcaacg aaggcgagcg aatgaggcat
    19021 cttttctggc gtcttaactt tctccttctc tccggggcaa caaacagcgc ccagatgtac
    19081 catgaggccg ccgctctttc ctccgagctg gatactcgtt ggtcttaccg ctccaaagag
    19141 cttatgacgc tctacagcaa ggcgaaatcc tatgaggctg gggaacgtgt cgagttcggc
    19201 ggaaagtcgt ttgcaccgct atacacgccc aaaaacgaca cgctgatcaa cctattccag
    19261 atctcacagc aagaacaaga gcaactgaag acgattatca gcactgacga ggctcagaag
    19321 cgccgcagag agcgcgatag actgcgtgat gaagaacgtc gccgcgccgc tggccagctt
    19381 gagcgtgaag cctatgaagc caactcattg agcaggcaaa agccctggga agctatgggc
    19441 atgagccggg ctaaatggta tcgcctgggc aagccttcac ctcaacaaaa cagtgagaca
    19501 agtccctccc ctattactaa tggcgaagcc tcagcggttg cccttcaggc ggccaggtgt
    19561 aaagccgttt agatggctat ttcaaagtga gtgagatttc gtaacggatg gcagccctag
    19621 aggctgcttt cttttgaggg gttagcaggc gtatagccat gctggatctc agtctatcac
    19681 tacctgctta atattccacc tttagatccg gcagcagttc gaccaggtgg ccaacttacc
    19741 aggcaccggc agcagctcga ccgggtggcc aagttcagat ctggacgcca gaaggaaatc
    19801 aaccaggtgg ccaacttacc aggcaccggc agcagctcga ccaggtggcc aagttcagat
    19861 ctggacgcca gaaggaaatc aaccaggtgg ccaactcacc aggcatcggc agcagctcga
    19921 ccaggtggcc catttcgtac gtacgaaatc aggcgacgct atgcgaaatc ttggcggcaa
    19981 tcccccgcga ctacgtgatt tttttaacgt agagcgcgct ttttcttgcc atagtaggcc
    20041 attttggcct ataatcttaa ttaagaagac cgggcacccg ccacggtcaa taccggagaa
    20101 ctccgatgat ccacacagct aaccgcacct ttcaccaact ctatcgagaa tggatacgcg
    20161 aacgccgcga gcatatgcac aacgttttga cctgggagcg tgatcgttac ggtgctcgcc
    20221 tcgtcggtct gttttatcgt tactgcaagg tggccaaccc ctttccccgt tgcactctga
    20281 atactcggat caactaccgc gcccatgcgg tgaatctgcc agattggcca gcccgcagcc
    20341 tggagctgaa taaaatgtgg ctcagttgga gagaaaaaaa gtaggccgat ttggcctatt
    20401 ttttattgta cccgcttgac acaataggcc aaaatggcct attatatatc tcagaaggcc
    20461 gggcacccgc cacggtcaat accggagaac tccgatgatg caaacagaac ttaatcccct
    20521 gatctgctcc ctggtcgcca cccctcgccg tatggctgca atgccccgct atgtaggccg
    20581 tttctatgtg gttttcgagt cgatgcttta ccagcaaatg aaagggctct gccgcgagta
    20641 tcgcggggct tattggctta tgtgggagct gtcgaacggc ggcttttata tggctcctgg
    20701 gcgtcgtgat gaaatgctga acatcgaggc catgaactac tttagtggcc aaatgagcgc
    20761 cgatgctgcc gggattaccg cttgcctcta cctctatagc catctgtcat ttcacacaga
    20821 aggcgctgac caggagcggt tttcaaggct gtatcacagc ttgcgggatt gggcttgtga
    20881 gcatgacgaa aaagaggcca tcttggccgc aatagactag caacagaaag ccccggtgat
    20941 ggccggggct cttaaaggag gtgcataggt agaaaaagaa atggtgcccc tggtatggct
    21001 gcaaccaatc acaggggctt tcaccggtca atttgaggat aaacgcgatg aatacggata
    21061 ttgtatcact tgcaaaacac attggcgacg ctctgacggc ccgccgcccc gttcatatgc
    21121 cgcgcatgaa gatgcgggag cttggcttgc tcttgattga actgaaggcg tatcgggagg
    21181 ccgccgcgac cgttacccat tgataaaaaa gccccggcat tgaccggggc tatttgagga
    21241 tttatcgcat gattagacct gaaacgctta ggccgttcgc tgaagattgg caggctccaa
    21301 ccgccgatga aatcaaagag gtgttggagc tgattaggca acgaaaaggg cttagtaagc
    21361 ctctcagtgg cgttgatgtc gctgatctcg ttggtttgcc tggtgagaga ggcagcggaa
    21421 agggaacccg aaccttcagg cgttgggtga gcaaaaccaa ccctagccct attgcttatg
    21481 gtgcctggtc tatcttggcc cacctggcag gtttcggggc tatatgggac gctgaccggg
    21541 attgaaacca tgaccgaaca taaggccgaa cgtgctccct ggggagactt cccggcagta
    21601 gtgaggaacg gcgatctaaa ggatctctct aaagaacctg aatacgaagc cgccaaacat
    21661 ggcgaccaca aggcgatgag ctataagcgc atgaagccgg ccgaggacga attgcattgc
    21721 gagatcaagg cgctgcttga tcgcgccaag gctaccgacg accaggagcg taacgagccg
    21781 gagctggaca ttcctgccga gatttctcgc cgcgagaagc gcctggaggc gatccaggcg
    21841 gcaaaggcgc gcctggaagc gcgccagcgt gaagcggacc aggcccgggg gcgcagcgaa
    21901 gacgatggcc gccggcctcg ccatccggat ggctcggaca agggcggtgg ctcgtacaaa
    21961 cgcgagtttg gtgtgccgga tgaccgtgat caggaaagct tcaccgatcc ggacagccgg
    22021 atcatgaaac acgccggtgg tggctccgag cagagctaca acgggtacac agcggtcgat
    22081 gccgagcacc agatcatcgt ggcggcggag ttgaccaact gcgccgcgga cagtcaggcg
    22141 ctgctgggca tgctggcagc agttcaggcc aacaccggag aaatgccggc ccagacgctg
    22201 gcggatgcgg gattccgtag tgaggctgtt ctggcaaagg tcgccgatca ccacggcgat
    22261 gtcatcgttg ccctcggccg cgagggacgt gaagatgcca aggtcaatgc caagacccat
    22321 ccgcatacgg cggcgattgc ggcgaaattg aaaacggagc aaggcgatgc agcttaccgc
    22381 cggcgcaagt cgatcgtgga ggctccgaat ggttggatca aggcggtgat gggattgcgt
    22441 cagttcagca tgaggggcct ggacaaggtg caagccgagt ggaagctcgt ctgcatggcg
    22501 ctaaatctga ggcgaatggc gtatctgtga gggcgaaggt taaatggggc ggctcaaatg
    22561 caccccagtc gtcataacac gccgcgcgcc gcaagattgg tatccttggc gccgacgcct
    22621 tgccaattgc agagagcgcc gccgccatcg tcagtgctct acagaaaacc ggtcacacgg
    22681 ctctgccgcg cagactccta gcctaaatgt gacagtggtt ggtaatccat gccgcccgca
    22741 agggcggcgg tggtgggcca atagatgatt ttcagagcct tactgcccgt tgacgcccaa
    22801 tccctcgagc gcgagtctag ccgcagcggc gatgacggcc tcgctgtgct tgtcatcctt
    22861 gttaggcgcc cgggtgtaga cggccaacac aataggtgcg cgcccagtgg gccagacgac
    22921 ggcatagtca tttgccgtgc catacactcc gcaggttccg gttttgtctc cgactgccca
    22981 gtctgccggc accgccgcgc ggatgcggtg gttgccggtc gtgtttccct ttagccaatc
    23041 aacaaactgc tgccgctgcg gcgcagccag tgcagagccc agtgtcagtt tttgtaagct
    23101 ttccgtcacg gcgcgcggcg atgaggtatc gcgcgcatcg cctgggatgg cggagttcag
    23161 ctccagctcc cagcggtcca gacggaacgt ggtatcgccg atagagcgca tgaaggccgt
    23221 cagcccggcc gggccgccca actccttcag caacaaattg gcggcggcgt tatcactgta
    23281 ttgcacggcg gccgcggaca gctccgccac cgtcatgcct gttgtcagat atttttccga
    23341 gatgggtgac cacggaacca gcgcattttt gccgtaacgg atgggtgtgt ccagcaagcc
    23401 ggcctgctgc tggctgcgag ccagcacagc ggcagcaaga aagcccttga atgagctgca
    23461 cagtgggaag cgctcctcag cgcggtaact tacagttgcg cctgagccgg tatccatcgc
    23521 gtacacaccg atggagccgc caaagtcctg ttcgagttta gcgaatggtt ccgcgacgag
    23581 gttggtcagc gcggtggcag aaaagccagc cagcggccat gagagacaag acagcagaac
    23641 tagacggcga tacagtgaca tcaacgatat tccttgtttg aaggtggagc taggtgtagc
    23701 ggccggatgt aatcaggccg ctacagctgg gattaggggt ctgacgctca gtggaacgaa
    23761 aactcacgtt aagggatttt ggtcatgaga ttatcaaaaa ggatcttcac ctagatcctt
    23821 ttaaattaaa aatgaagttt taaatcaatc taaagtatat atgagtaaac ttggtctgac
    23881 agttaccaat gcttaatcag tgaggcacct atctcagcga tctgtctatt tcgttcatcc
    23941 atagttgcct gactccccgt cgtgtagata actacgatac gggagggctt accatctggc
    24001 cccagtgctg caatgatacc gcgagaccca cgctcaccgg ctccagattt atcagcaata
    24061 aaccagccag ccggaagggc cgagcgcaga agtggtcctg taactttatc cgcctccatc
    24121 cagtctatta attgttgccg ggaagctaga gtaagtagtt cgccagttaa tagtttgcgc
    24181 aacgttgttg ccattgctgc aggcatcgtg gtgtcacgct cgtcgtttgg tatggcttca
    24241 ttcagctccg gttcccaacg atcaaggcga gttacatgat cccccatgtt gtgcaaaaaa
    24301 gcggttagct ccttcggtcc tccgatcgtt gtcagaagta agttggccgc agtgttatca
    24361 ctcatggtta tggcagcact gcataattct cttactgtca tgccatccgt aagatgcttt
    24421 tctgtgactg gtgagtactc aaccaagtca tttttcaata ttattgaagc atttatcagg
    24481 gttattgtct catgagcgga tacatatttg aatgtattta gaaaaataaa caaatagggg
    24541 ttccgcgcac atttccccga aaagtgccac ctgacgtcta agaaaccatt attatcatga
    24601 cattaaccta tatgtcaaga cccggctggt tatacacgcg tttcctgaac aattcagggc
    24661 gtttttcatg ccattccttg agcgcctgaa cgggtgtttt gtgttggagc gcgcgttgcg
    24721 gaatgctgtg gttgtagatc ttgacgtaat tgcgcagcgt cgattccagt tcggcagctg
    24781 aaccaaaacg ggtctggttg acgatgtcgc tgatacgacc gttgaagcgc tccaccatgc
    24841 cgttggtctg cggatgacga ggcgggatga gccggtgctc gatgccgagc tgcttgcaca
    24901 ggcggtcgaa cacgtgtgtg ccgctgggtt ccttcttctt gccgccagcc gtgaagcggt
    24961 cggtgaactg gctgccgttg tcggtcagaa gcttgacgat cttgacggga caggcttgct
    25021 ggactttgtt gaggaagtcg ccactgctgc catcggtctg gtcggcatag agctcgatga
    25081 agacccagcg cgtagcacgg tcgatggcaa cgaagagata gcgccttgcc gtctcgtcgg
    25141 gcatctgcgg caggtacttg atgtcgatgt gcacaaagcc cggctcgtag tccttgaagg
    25201 tctttttcgt ggcgggcgca gtgccttcct gctcgaccag gttacgtaga tccgagacac
    25261 cgtggcggcg caggcaacgt cccaggccgg cacgcgagac ggctggattg atgaactcgc
    25321 gcgtgaccgc cagcaggtcg tccgtgggca gcagcaacgt cttgcgcagc tccaccacga
    25381 tgagctcctg ctcgggcgtg agcgtcgtgt acatcttgtt cggcgcatgc gacttgtctt
    25441 caggagactc gcggttttgc cactttcgga tggtttggcg ggtgacgttg tacatcctgg
    25501 ccagttcggc ctgcgggagc gtcgagttcc tgatttcctc acggatcagg tgggtagtac
    25561 gggcttggct gtgcagtgcc tgggtcatcg agttgccagt gaagagtcgg attggaacag
    25621 tgtacgcaaa acgtgtctgg ccttgaagag cggccagcta cgcatgggta catgatccca
    25681 cgagtccaga cacctataaa aataggcgta tcacgaggcc ctttcgtctt caagaatttt
    25741 ataaaccgtg gagcgggcaa tactgagctg atgagcaatt tccgttgcac cagtgccctt
    25801 ctgatgaagc gtcagcacga cgttcctgtc cacggtacgc ctgcggccaa atttgattcc
    25861 tttcagcttt gcttcctgtc ggccctcatt cgtgcgctct aggatcctcc ggcgttcagc
    25921 ttgtgccaca gccgacagga tggtgaccac catttgcccc atatcaccgt cggtactgat
    25981 cccgtcgtca ataaaccgaa ccgcgacacc ctgagcatca aactctttta tcagttggat
    26041 catgtcggcg gtgtcgcggc caagacggtc gagcttcttc accagaatga catcaccttc
    26101 ctccaccttc atcctcagca aatccagccc ttcccgatct gttgaactgc cggatgcctt
    26161 gtcggtaaag atgcggttag cttttacccc tgcatctttg agcgctctga tctgaatatc
    26221 gagggactgc tggctggttg agacccgcgc ataaccaaaa attcgcataa aatgtacctt
    26281 aaatcgaata tcagacacga tgtgtctatt atgccaaaat gacgatttaa tggacactca
    26341 aacgaagccg ttttactatg tctgataatt tataacattt cggacggttg caaaaatgtt
    26401 actaaatgcc cgtcaggcag ggaggccgat atgcccgttg actttctgac cactgagcag
    26461 actgaaagct atggcagatt caccggtgaa ccggatgagc ttcagctggc acgatatttt
    26521 catcttgatg aagcagacaa ggaatttatc ggaaaaagca gaggtgatca caaccgtctg
    26581 ggcattgccc tgcaaattgg atgtgtccgt tttctgggca ccttcctcac cgatatgaat
    26641 catattcctt ccggcgtccg gcattttacc gccagacagc tcgggattcg tgatatcacc
    26701 gttcttgcag aatacggtca gagggaaaat acccgccgtg agcatgcagc gctgatacgt
    26761 cagcactatc agtatcgtga atttgcctgg ccctggacat ttcgccttca tgtacagaac
    26821 cttaagcggc aagcgaatta ataataccgt ctaacgtgtt gttttgcttg gattttctct
    26881 gcctactctt tttgccgttt ttggataaat acaccattgc ccactccaac ttctctgtta
    26941 tttcctgcca cgcaccatgg atgatgctcg ccaatatcgg cattaaccaa agcgcgctgt
    27001 ttttggcaat cttcagcatc gataactccg cgctgccaat cagcgtcagc gccagccgac
    27061 gtttgaccag caaggccagc aaactagccc agatcaagcc ttccgctatc gctttttgtc
    27121 gtgtcgcgaa cgccttcaac cggttatgtg atttcagctc tttgaacaac agttcgatct
    27181 gccaacggca acgatacaat gccatcacct tctcggctgg ccatcgctca cgcggaagat
    27241 tggtcatcca tatacagaac cgtttttcct ctgcaaacca acgtcttatg agtcgatatt
    27301 tatactttcc cgaactcaca tccagatcca gaacctcggc tctgcagctt ctccgatcga
    27361 tatccttgag cttttttccg agtaacttgg gcatttccct gccgtcctgt cggtaagctg
    27421 cctgtacttt gggattgaga ttttgactcc ctctgaccag atagcttcct ttggctttgg
    27481 tcacatcagc aaagtactcg cggctgatgt aaccggcatc cgccaataac agtttgttat
    27541 ttaacgaatt ttcggccgga agatgcttgc gctccgattc ggtatccgcc gtgatactca
    27601 tcgatatcgg cgactggtcc agcaaggaca tggtcatatg acactctacc gcagcggggc
    27661 tgtgcttatt gaatcggccc gggaaatgtt ctgccaattg cggatgtaac gcgaatgacg
    27721 acccgtcctg cagcagtacc tgctcaaagc ctgccagtcc gtgggcgtcc ggtagacact
    27781 ccttgaggcg taaggcgatg gctcgttcaa ccagtgcgcg catgaacaag ggaaaaccct
    27841 gcttgcgtaa ctggttgtga aagggtttat acgctatttg gtcagtatca tggagctgca
    27901 acgcattgaa atggcgatgc aaaccagcaa taccatccac cttgtcgcaa ccaagccctg
    27961 agagcagagc cgggagtagt ctcgcaggct ggatatcccg gagtcgctga caaaaaccgg
    28021 taaatttacc gatccggttg agttcagaag agctaagaag ttgcttgagg tactgggttg
    28081 cattgataat agtcatggct tcgggcgtgt cggttttttt ttgcgattaa atcagatcac
    28141 aaacgaagcc ttttttctat ctatttcaat tggttgtagc taaagatcct gtacatgaca
    28201 ggtcactgca gcggccaaac tgttgccaca tctcagttca ggaggaaacg caatgactca
    28261 ggaaaggatc cagacccgct acccactcgg cggccccttc gccacccagg ctgagctgga
    28321 gcaggccatc acccaggcca taacgaccca cagacaagat ttcttccctc tgctggaacg
    28381 gctggtggac gtgggggaca cccgggtcaa cctcagtcag gagaacccgc tgcgggtgct
    28441 cagcatcgaa ctcgctgacg gccgtgaagg agtggcccat atcaactacg agtccaactt
    28501 cgccgagagc tgcctgatta tcaacgaata cgaccagcac cagaccagcc tggcctttcg
    28561 cctcgacggg gatgcactta tcttcgacgt cgaactgccg atcgcgtgga atttcaataa
    28621 ctgaagattc agcggtgtaa tgccgcctgg ttgctacacc cggtcagcca gctcccctca
    28681 ccctaaccct ctcccaaagg gagaggggat cagcccgtgc caacctccag ccgtggtagt
    28741 cactccatac tctgctgtta tttcaggcgc ctgtaatctt ccccatatgg ctgtcatctg
    28801 aatagcaata tccagcatat agccaccata accctcactc atgtacagga tctttagcgg
    28861 caaccaattg aaatagatat aaaaaaggct tcgtttgtga tctgatttta tcgccaaaca
    28921 aaatcaacac gcgcgaagcc tatgactatt atcaacgcta attactatct ggagcaactc
    28981 ttggctcccg ccgcactcga gcgcattgct cggctctgca agttttgtct gcgtcagcgt
    29041 gccattaccc cagccatgct cgtacctgca ctgctgcggg ccatgggagg cgaccaggtc
    29101 aatgacattg ccggtttaca ccgccatttc aatgccttgc aactggtaaa cacccatcag
    29161 gtttcttaca aaccgtttca caatcagctg cgcaaagaga gctttgccct gtttatgaaa
    29221 gccctggtcg agcgggccat cgccttgcgt atcgaccatc aactcaaagc agcctccctc
    29281 ggcgcgttca agcaggtgtt actgcacgat ggcacctcct ttgcggtgca tcggcgcctt
    29341 gctgctgatt ttcccggccg gttcaagacc atcagtccgg cagctatcga gtgccatatg
    29401 accatgtcac tgtcggagca gagcccgttg tgcatgagtg tgtctgccga taccgcaggg
    29461 gaacggcaat ttctgcctga agcccacacg ctgaccaact gcctgctgct ggctgacgca
    29521 ggttacattg acagggcttg gtttgagcag gtgaacgacg ctggcggatt ttatctggtg
    29581 cgcggcacga aaagcctgaa ccccaagata atccaagcct ggcgcggtga tggacgggaa
    29641 gtacccaagc tggcgggact atctctgaga gaggccggac ggcgacgctg tcgggccgag
    29701 gtactggata tggtggtgaa gtccggccag gtcgagtacc ggttgatccg gcgctggttt
    29761 gctgaggaaa agcggttctg tctgtggatg acgaacctac cgcgagcagc atggtcagca
    29821 gagcaggtga tgagcctgta tcgctgccgt tggcaggtgg agttgttatt taaagagtgg
    29881 aaatcgcaca accggctcaa ggggtttgtg acgggcgaga aagcgattgc cgaggggttg
    29941 gtgtggacga gcctgctgtc gctggtgatg aagagacggg tcgcgcagag tgtgatgagt
    30001 ggggcgctat cgatgctgaa agcgtcgaag aacagtgcga cgtggtggct accgctattg
    30061 gaagcagtgg cccatagggc gctgacagaa ataagggaaa gattggaatg ggctgccgat
    30121 tatttggcca agaacgcctg ccgaaccaag cagagaaagt cgatacagaa caggaccttg
    30181 gaaggcgttt taaatggact cgccgcttaa ggtcctgtac atgatttcgc cttacccgtc
    30241 ttttatatac ccggagctgg ataagcaacg aacgtcctgg cctgcttttc gatctggcga
    30301 cagggtggct tatgcaacat cgtattattc tccccggagc cactacgctg acccggttga
    30361 tttcagaggt aagggaaaag gcgacgttgc gcctgtggaa caaactggca ctgataccgt
    30421 cagccgaaca acgttcacag ctggagatgc tgctggggcc aactgattgc agccgcctgt
    30481 ctttactgga atcactgaaa aaaggccctg tgaccatcag tggtccggcg tttaatgaag
    30541 caattgaacg ctggaaaact ctgaacgatt ttggcttgca tgctgacaac ctgagtacac
    30601 tcccggctgt gcgcctgaaa aatctcgcac gttatgctgg tatgacttcg gtgttcaata
    30661 ttgccaggat gtcaccgcag aaaaggatgg cggttctggt tgcctttgtc cttgcatggg
    30721 aaacgctggc gttggatgat gcactggacg ttctggacgc catgctggcc gttatcatcc
    30781 gtgacgccag aaagattggg cagaaaaaac ggctccgctc gctgaaggat ctggataaat
    30841 ctgcattggc gctcgccagc gcatgttcgt acctgctgaa agaagaaaca ccggacgaat
    30901 cgattcgtgc tgaggtgttc agctacatcc ccaggcaaaa gctggctgaa atcatcacgc
    30961 ttgtccgtga aatttcccgg ccctcagacg ataattttca tgaagaaatg gtggagcagt
    31021 acgggcgcgt tcgtcgtttc ctgccccatc tgctgaatac cgttaaattt tcatccgcac
    31081 ctgccggggt taccactctg aatgcctgtg actacctcag ccgggagttc agctcacggc
    31141 ggcagttttt tgacgacgca ccaacggaaa ttatcagtcg gtcatggaaa cggctggtga
    31201 ttaacaagga aaaacatatc acccgcaggg gatacacgct ctgctttctc agtaaactgc
    31261 aggatagtct gaggcggagg gatgtctacg ttaccggcag taaccggtgg ggagatcccc
    31321 gagcaagatt actacagggt gctgactggc aggcaaaccg gattaaggtt tatcgttctc
    31381 tgggacaccc gacagacccg caggaagcaa taaaatctct gggtcatcag cttgatagtc
    31441 gttacagaca ggttgctgca cgtcttggcg aaaatgaggc tgtcgaactc gatgtttctg
    31501 gcccgaagcc ccggttgaca atttctcccc tcgccagtct tgatgagccg gacagtctga
    31561 aacgactgag caaaatgatc agtgatctgc tccctccggt ggatttaaca gagttgctgc
    31621 tcgaaattaa cgcccatacc ggatttgctg atgagttttt ccatgctagt gaagccagtg
    31681 ccagagttga tgatctgccc gtcagcatca gcgccgtgct gatggctgaa gcctgcaata
    31741 tcggtctgga accactgatc agatcaaatg ttcctgcact gacccgacac cggctgaact
    31801 ggacaaaagc gaactatctg cgggctgaaa ctatcaccag cgctaatgcc agactggttg
    31861 attttcaggc aacgctgcca ctggcacaga tatggggtgg cggagaagtg gcatctgcag
    31921 atggaatgcg ctttgttacg ccagtcagaa caatcaatgc cggaccgaac cgcaaatact
    31981 ttggtaataa cagagggatc acctggtaca actttgtgtc cgatcagtat tccggctttc
    32041 atggcatcgt tataccgggg acgctgaggg actctatctt tgtgctggaa ggccttctgg
    32101 aacaggagac cgggctgaat ccaaccgaaa ttatgaccga tacagcaggt accagcgaac
    32161 ttgtctttgg ccttttctgg ctgctgggat accagttttc tccacgcctg gctgatgccg
    32221 gtgcttcggt tttctggcga atgggccatg atgccaacta tggcgtgctg aatgatattg
    32281 ccagagggca atcagatccc cgaaaaatag tccttcagtg ggacgaaatg atccggaccg
    32341 ctggctccct gaaactgggc aaagtacagg cttcagtgct ggtccgttca ttgctgaaaa
    32401 gtgaacgtcc ttccggactg actcaggcaa tcattgaagt ggggcgcatc aacaaaacgc
    32461 tgtatctgct taattatatt gatgatgaag attaccgccg gcgcattctg acccagctta
    32521 atcggggaga aagccgccat gccgttgcca gagccatctg tcacggtcaa aaaggtgaga
    32581 taagaaaacg atataccgac ggtcaggaag atcaactggg cgcactgggg ctggtcacta
    32641 acgccgtcgt gttatggaac actatgtata tgcaggcagc cctggatcat ctccgggcgc
    32701 aaggtgaaac actgaatgat gaagatatcg cacgcctctc cccgctttgc cacggacata
    32761 tcaatatgct cggccattat tccttcacgc tggcagaact ggtgaccaaa ggacatctga
    32821 gaccattaaa agaggcgtca gaggtagaaa acgttgctta acgtgagttt tcgttccact
    32881 gagcgtcaga ccccttttac gcgggtatgg acgcgccgat gaaactgcat tggcatcact
    32941 gctggaggtc agcgactggg agcgcatcgc ccggcaggag cttgagcgcc gggctaccag
    33001 catcgtgcag gcgctggatg atgcgaccct tgaggccatc gcagcgggca cgctcgacat
    33061 gctggccatg tgccgacagg tggccgacga gatccaccag gccgcctaag ccctcccctg
    33121 ccctgccacc gaaccccgcc gcgtgcgggg ttttttatga cttcaaatcc tcaaaaggtg
    33181 catttactca aatcctcaat atgctatact gcgcttgagt aattcctttt ttcctcaaac
    33241 gctcaatagc tcaaggagcg catatgcaag tcattgctgt actgaaccag aagggcgggg
    33301 cgggtaaaac caccatcgcc acccaccttg cccgcgccct gcaactcgac ggcgcagacg
    33361 tgttgctggt tgattctgac ccgcagggca gcgcccgcga ttgggccgcc gtccgcgagg
    33421 atcaacccgt gcccgtggtt ggcatcgacc ggcccaccat cgagcgcgat ctaaagagcg
    33481 tggcccggaa agactttgtt gtgatcgacg gagcgccgca ggctcatgac ttggccgtgt
    33541 cggcaatgaa gtccgccgat tgcgtgctga tcccggtgca gccgtcgccc tacgacattt
    33601 gggcaacctc tgacctcgtg gatttggtca agcagcgcat cgagctgacc gacggcaagc
    33661 taaaagcggc tttcgtggtg tcccgtgcga tcaagggcac caagattggt gcggaagtct
    33721 ccgaggcgct ggccgggtac ggcctgccga tcctgcaaac gcgcatcacg cagcgcgtca
    33781 tctacccgag cagcgcggcc agcggcacca cggccattga ccaagagccg acgagcgagg
    33841 ccgccgagga aatccgggcg ctggctgagg aagtgcgccg tttcctcaat tgcaccattt
    33901 gagtaattaa ggagtaggtg aaaatgagta gcgggaaact tggcatgaaa gcaggccgcc
    33961 cgagcgccgc gaaggctggc cctaccttgt ccgaccttgc cgacaaggcc gccaccgtcc
    34021 gggtgaattt cgacctcgac cgggccgagc acacgaagct gaagatttac gccgccaaga
    34081 ccgggcgcag catcacggac attctgcgcg aactggtgcg ctcacttgat gaaaagagtg
    34141 attgagtaat cacttaaccg gctggacggg tcaaaagcat ggactatagt ccatacattt
    34201 ttgatttggc gaaatttaat aatgttgatg aaatacggcg cgtggggtat aaagtgatgg
    34261 ttgaaatgga accgttgagt ctggaggtac tgccgccctc tcatttcaag gcgtttgcga
    34321 agaacgcacc gcatgagatc aagggcgctg tcatcgagaa cacagagcgc gggctggtga
    34381 tcgtgctgca cgttggcaac gagcggcgca ttctcggcca gtaccgggga ggcatccggt
    34441 tttttcgctc tttcgatggc gcggcggcag tgctgcggca gcatggcgtg ctgcactgga
    34501 cggcgaatgc aaaaggctgg attccgcgaa ctttggaagc gaaggagcgg agttcagatg
    34561 gatgaaaaag caaagccccg cgtggcagcg gggcttggca gggggcggga ctagtcaggt
    34621 ggcactggct agaacccaaa ggcgcaacct atacaggcaa cacccagaca tggtttgcat
    34681 tgtagcgccc cacctcttgc cgcacaagcg gaaagaaggt t
//
