LOCUS       NZ_CP080005            20708 bp    DNA     circular CON 03-SEP-2023
DEFINITION  Staphylococcus aureus strain D94 plasmid pD94, complete sequence.
ACCESSION   NZ_CP080005
VERSION     NZ_CP080005.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN20294502
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 20708)
  AUTHORS   He,T. and Liu,Y.
  TITLE     Staphylococcus aureus Genome of the plasmid
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 20708)
  AUTHORS   He,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-JUL-2021) College of Animal Medicine, Xinjiang
            Agricultural University, No. 311 East Nongda Road, Bayi Street,
            Urumqi, Xinjiang 843000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: other plasmidid v. 1.6.5
            Genome Representation             :: Partial
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 09/02/2023 04:18:05
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 25
            CDSs (total)                      :: 25
            Genes (coding)                    :: 21
            CDSs (with protein)               :: 21
            Genes (RNA)                       :: 0
            tRNAs                             :: 0
            ncRNAs                            :: 0
            Pseudo Genes (total)              :: 4
            CDSs (without protein)            :: 4
            Pseudo Genes (ambiguous residues) :: 0 of 4
            Pseudo Genes (frameshifted)       :: 3 of 4
            Pseudo Genes (incomplete)         :: 1 of 4
            Pseudo Genes (internal stop)      :: 2 of 4
            Pseudo Genes (multiple problems)  :: 1 of 4
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP080005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..20708
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="D94"
                     /host="cattle or sheep"
                     /db_xref="taxon:1280"
                     /plasmid="pD94"
                     /geo_loc_name="China:Kurle"
                     /collection_date="2018-10"
     gene            complement(11..619)
                     /locus_tag="KZO21_RS00005"
                     /old_locus_tag="KZO21_00005"
     CDS             complement(11..619)
                     /locus_tag="KZO21_RS00005"
                     /old_locus_tag="KZO21_00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002436987.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_044033836.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGKSIENRPV
                     LQEALNFLRMGDRFVVESIDCLGRNYDEVIHTVNYLKDKEVQLMITSLPMMNEVVGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGIYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGQSISKIAKEVNITRQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            complement(988..1833)
                     /gene="blaZ"
                     /locus_tag="KZO21_RS00010"
                     /old_locus_tag="KZO21_00010"
     ARG             complement(992..1833)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            1940..3697
                     /gene="blaR1"
                     /locus_tag="KZO21_RS00015"
                     /old_locus_tag="KZO21_00015"
     ARG             1941..3694
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.56"
                     /coverage="100.0"
     gene            3687..4067
                     /gene="blaI"
                     /locus_tag="KZO21_RS00020"
                     /old_locus_tag="KZO21_00020"
     ARG             3688..4064
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            4331..4924
                     /locus_tag="KZO21_RS00025"
                     /old_locus_tag="KZO21_00025"
     CDS             4331..4924
                     /locus_tag="KZO21_RS00025"
                     /old_locus_tag="KZO21_00025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690638.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            4896..6339
                     /locus_tag="KZO21_RS00030"
                     /old_locus_tag="KZO21_00030"
                     /pseudo=""
     CDS             4896..6339
                     /locus_tag="KZO21_RS00030"
                     /old_locus_tag="KZO21_00030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /name="DDE-type integrase/transposase/recombinase"
     gene            6332..7147
                     /locus_tag="KZO21_RS00035"
                     /old_locus_tag="KZO21_00035"
     CDS             6332..7147
                     /locus_tag="KZO21_RS00035"
                     /old_locus_tag="KZO21_00035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000164958.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYNAPAEKQTKLRNDLYSITAIIDL
                     GQKLHVVNKYGHEHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            complement(7267..8241)
                     /locus_tag="KZO21_RS00040"
                     /old_locus_tag="KZO21_00040"
     CDS             complement(7267..8241)
                     /locus_tag="KZO21_RS00040"
                     /old_locus_tag="KZO21_00040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="WP_000072391.1"
                     /translation="MSNTKIKYQIFISSTYLDLIEERQAVVEAVLNSNNIPAGMELFNS
                     SSKSQWEIITQWINESDAVILLLGSSYGTIDSEENISYTEMEYNFAKSLGKPIYVFEMN
                     KASTESAEKSKKLDEFKTKVKENRLISPNINDISELKSKVSQTLMQSVPSEIKENSGWI
                     RVQDCGKNVKKLKKLDAIQRDLDTYDFLKEELYKIFMYVKTFYFQHTPFDDSYIEDIEN
                     YLLNYENNPHKSFMKIKVYDYKNFLKHLKNILILIKQGKKPLAQAGHFKLSFYEEDLKL
                     LQKNYKTTLVDIKGLNKHFYKECDRCLKAYNIFIEGINKHLYE"
                     /name="DUF4062 domain-containing protein"
     gene            complement(8453..8545)
                     /locus_tag="KZO21_RS00045"
                     /old_locus_tag="KZO21_00045"
     CDS             complement(8453..8545)
                     /locus_tag="KZO21_RS00045"
                     /old_locus_tag="KZO21_00045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(8714..9061)
                     /locus_tag="KZO21_RS00050"
                     /old_locus_tag="KZO21_00050"
     CDS             complement(8714..9061)
                     /locus_tag="KZO21_RS00050"
                     /old_locus_tag="KZO21_00050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119691.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNQEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            complement(9080..9697)
                     /gene="cadD"
                     /locus_tag="KZO21_RS00055"
                     /old_locus_tag="KZO21_00055"
     ARG             complement(9084..9697)
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="99.51"
                     /coverage="100.0"
     gene            complement(10908..>11190)
                     /locus_tag="KZO21_RS00120"
                     /pseudo=""
     CDS             complement(10908..>11190)
                     /locus_tag="KZO21_RS00120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(11201..11877)
                     /locus_tag="KZO21_RS00060"
                     /old_locus_tag="KZO21_00060"
                     /pseudo=""
     CDS             complement(11201..11877)
                     /locus_tag="KZO21_RS00060"
                     /old_locus_tag="KZO21_00060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            12288..13031
                     /locus_tag="KZO21_RS00065"
                     /old_locus_tag="KZO21_00065"
     CDS             12288..13031
                     /locus_tag="KZO21_RS00065"
                     /old_locus_tag="KZO21_00065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843758.1"
                     /translation="MKSVKRLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESATEDKQKKESDNINFESKSDAQIVEILKNQINTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNAR
                     QNVDAQEKTYTTSPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAQREDVSANPND
                     NDSDIEEKSEETEPKKGFWSRLFGN"
                     /name="DUF536 domain-containing protein"
     gene            complement(13250..13435)
                     /locus_tag="KZO21_RS00070"
                     /old_locus_tag="KZO21_00070"
     CDS             complement(13250..13435)
                     /locus_tag="KZO21_RS00070"
                     /old_locus_tag="KZO21_00070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466619.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSVWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            13584..13655
                     /locus_tag="KZO21_RS00075"
                     /old_locus_tag="KZO21_00075"
     CDS             13584..13655
                     /locus_tag="KZO21_RS00075"
                     /old_locus_tag="KZO21_00075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_106873653.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGY"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(13894..14235)
                     /locus_tag="KZO21_RS00080"
                     /old_locus_tag="KZO21_00080"
     CDS             complement(13894..14235)
                     /locus_tag="KZO21_RS00080"
                     /old_locus_tag="KZO21_00080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000761341.1"
                     /translation="MKLAEAIKEQRELKGWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRVPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(14322..15182)
                     /locus_tag="KZO21_RS00085"
                     /old_locus_tag="KZO21_00085"
     CDS             complement(14322..15182)
                     /locus_tag="KZO21_RS00085"
                     /old_locus_tag="KZO21_00085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000145511.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            15323..15502
                     /locus_tag="KZO21_RS00090"
                     /old_locus_tag="KZO21_00090"
     CDS             15323..15502
                     /locus_tag="KZO21_RS00090"
                     /old_locus_tag="KZO21_00090"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_064138749.1"
                     /translation="MWQKHSFYVAKTLLLCGKNTPLGIEIPCCSRAEQAPKKVFKKIYK
                     NILKSSRGATYFSS"
                     /name="hypothetical protein"
     gene            complement(15544..16089)
                     /locus_tag="KZO21_RS00125"
     CDS             complement(15544..16089)
                     /locus_tag="KZO21_RS00125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001805533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001802578.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTDFEKYTKQIKAAQMILD
                     DYECIKSGKSLKKAEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSENEKKYKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQEREIIFKEDREDGYTL"
                     /name="hypothetical protein"
     gene            complement(16183..16812)
                     /gene="mobV"
                     /locus_tag="KZO21_RS00130"
                     /pseudo=""
     CDS             complement(16183..16812)
                     /gene="mobV"
                     /locus_tag="KZO21_RS00130"
                     /inference="COORDINATES: protein motif:HMM:NF013258.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            complement(17050..17676)
                     /locus_tag="KZO21_RS00100"
                     /old_locus_tag="KZO21_00100"
     CDS             complement(17050..17676)
                     /locus_tag="KZO21_RS00100"
                     /old_locus_tag="KZO21_00100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000593103.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            complement(17688..17999)
                     /locus_tag="KZO21_RS00105"
                     /old_locus_tag="KZO21_00105"
     CDS             complement(17688..17999)
                     /locus_tag="KZO21_RS00105"
                     /old_locus_tag="KZO21_00105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WP_000831610.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            complement(18003..19937)
                     /locus_tag="KZO21_RS00110"
                     /old_locus_tag="KZO21_00110"
     CDS             complement(18003..19937)
                     /locus_tag="KZO21_RS00110"
                     /old_locus_tag="KZO21_00110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WP_000713729.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTAIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLILKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTLDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            complement(20012..20305)
                     /locus_tag="KZO21_RS00115"
                     /old_locus_tag="KZO21_00115"
     CDS             complement(20012..20305)
                     /locus_tag="KZO21_RS00115"
                     /old_locus_tag="KZO21_00115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WP_000726502.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     ARG             complement(989..1833)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     BGC             15012..20708
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          complement(10704..10851)
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.333"
                     /coverage="100.0"
                     /evalue="2.96e-25"
     Typing          12289..13031
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(14323..15182)
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(16538..16812)
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="94.565"
                     /coverage="100.0"
                     /evalue="4.71e-46"
ORIGIN
        1 acaaagttta ttaaatcaaa tcattatcgt ttttaattct gtaaatcgtc tgccttgtta
       61 tatttacttc tttcgcaatt ttactaattg attggccttc ttctaacatt tctacaacgc
      121 gatgataaat aatacgtttc tgtggatctt tagcatttgg tgaataaagt aaggggcgcc
      181 ctttatatat gcctttttcc ttcgcaactt gaattccttg cgcttgtcga cgtttacttt
      241 catttctctc ttgttctgaa accattgcta atatttgaat aattaaatct ttcataaact
      301 tatccagtaa tggattgcca accacttcat tcatcatagg taagctagta atcattaatt
      361 gtacttcttt gtcttttaaa taattaacgg tatgaatcac ttcatcataa ttacgaccta
      421 aacaatcaat ggattctact acaaaccgat ctcccatcct caaaaagtta agtgcttctt
      481 gaagtactgg tctattttca atagatttcc cagactgttt ttctgtaaat attttttcag
      541 cacaaaacgt ctttaaattt tcaagttgtc tttctaaatt ttgatcgttc gatgatactc
      601 tcgcatagcc aacaatcatt gatttccatc tcataattaa tatacaccct aatcatacgt
      661 ttcagttact ataaattcaa caattatgtc actttgcttg atatatgaga attatttaac
      721 cttataaatg agaaaaaagc aacgcacttt aaataagata cgttgctttt tcgattgatg
      781 aacacctata attaaactat tcatctgtta tttatgattt tttgtatata caatatttct
      841 agtttgttaa agagaattaa gaaaataaat ctcgaaaata ataaagggaa aatcaggttt
      901 tgatatcaaa attatacatg tcaacgataa tagaaaatat aatacaaact ataagatgtt
      961 atcagtattt attatgcatt tagaatatta aaattccttc attacactct tggcggtttc
     1021 acttatcaac ttatcatttg gcttatcact tttattgtct ttattcgtaa aaatgactaa
     1081 aacaataggt tcagattggc ccttaggata aacaaaagca acatcatttc tagaagcata
     1141 tgttattgct tgaccacttt tatcagcaac cttatagtct tttggaacac catctttaat
     1201 taaagtgtct ccgtttttat tattaaacat taaatcaagt aagaaatttt tatttttttt
     1261 gcttaatttt ccatttgcga taagtttatt taaagtcttg ccgaaagcag caggcgttga
     1321 agtatctttt ttgctctttg gcgaatagta atttaattct atctcatatc taactggatt
     1381 tgttacttta tctcctagtt cttttagacg ttgtttaact tttttgattc caccgatttc
     1441 ttttataatt ttattgtttg ctgtattatc actatatgtc attgaagcct caataagttc
     1501 ttttaaagtg atgtcttttc ctacatattt ttctaaaata ggagaataag caactatatc
     1561 atctttgtta atatgtactt ttttatttaa cttattataa ggtacttgtt ctaacaaaat
     1621 agcactattt atcgcttttg aagtcgaagc ataggcaaat ctcttatctg aattaaattt
     1681 tacttcctta ccacttttag tatctaaagc ataaacacca atatgagcat tatatttttt
     1741 ttctaaatca tttaactctt tggcatgtga actgtttgaa ttacatgcac ttaaaactaa
     1801 agccattaca attaaaaata ttaacttttt caaaataaac cctccgatat tacagttgta
     1861 atttttacaa aacaataata ttacaattgt aatattgatg tcaattgttt attataaata
     1921 tttgaaagaa ggtgtcaaaa tggctaaatt actaataatg agtgtagtaa gcttttgttt
     1981 tatatttcta ttgttagtat tttttaggta catattaaaa cgctatttta attatagttt
     2041 aaattataaa gtttggtatc taactgtgct tgctggatta attcctttta tcccaattaa
     2101 attctctttt ataaaattta ataatgtgaa taatcaagcg cccacagttg aaagtaagtc
     2161 acacgacttg aaccataaca taattaccac caaacctgtt caagagttcg caacagatat
     2221 ccataagttt aattgggatt caattgataa tatctgcaca gttatttgga tagttttagt
     2281 tattatttta agttttaaat ttttgaaagc cttattatat cttaaatatt taaagaaaca
     2341 gtcactttat ctaaacgaaa atgaaaaaaa taaaatagat acgatacttt tcaaccatca
     2401 atataaaaaa aatattgtga ttcgaaaagc agaggctatt caatctccaa taactttttg
     2461 gtatgggaaa tatattattt tgattcctag ttcatatttt aaaagtgtaa ttgataaaag
     2521 actaaaatat ataatactgc atgaatatgc tcatgctaaa aatagagata ctttacattt
     2581 aattatcttt aatatcttct ctattattat gagttacaat ccattagtac atattgtaaa
     2641 aagaaagata attcatgaca atgaagtaga agccgataga tttgtcctta ataatattaa
     2701 caaaaatgaa tttaaaactt atgcggaatc tattatggac tccgtattaa aaacctcatt
     2761 tttcaacaaa aatatattaa gccattcatt taatggtaaa aaatcattac tcaaaaatag
     2821 attaattaat ataaaagaag ccgatctgaa aaagcagtca aaattaattc taatttttat
     2881 ttgtattttt acttttttta tcatgataat tcaaagccag tttttaatgg ggcaatcctt
     2941 aactgattat aattataaaa agcccttaca aagcgattac caaattttag atgaaagtaa
     3001 aaattttggt tcaaatagtg gatctttcgt tatgtacagc atgaagaaag acaaatacta
     3061 tatttataat gaaaaagaaa gtagaaaaag atattctcct gattcaactt acaaaattta
     3121 tttagcactg tttggacttg accgtcatat tataagtgat aaaaattcac gtatgtcatg
     3181 gaatcataaa cattatcttt tcgagtcttg gaataaggaa caagatttaa atacagcaat
     3241 gcaaaattca gttaattggt acttcgaacg tattagtaat caaataccaa agaactatac
     3301 tgcggctcaa ctcaagcaat taaattatgg taatgaaaat ttgggaagtt ataaaagcta
     3361 ttggatggaa gatagtttga aaatatctaa tcttgaacaa gtaatagttt ttaaaaatat
     3421 gatggaacaa aataaccatt ttagtaaaaa agcaaagaat caattatctt cttcattatt
     3481 gattaagaaa aatgaaaagt atgaactgta tgggaaaaca ggtacaggta tagtaaacgg
     3541 gaagtataat aatgggtggt ttgtaggtta cgtaattaca aatcatgata agtattattt
     3601 tgctacacat ttatcagatg gaaacccgtc tgggaaaaat gctgaattaa taagtgaaaa
     3661 aatattaaaa ggaatgggtg ttttaaatgg ccaataagca agttgaaata tctatggctg
     3721 aatgggatgt tatgaatata atatgggata aaaaatcagt atcagctaat gaaattgtag
     3781 ttgaaattca aaaatataaa gaagttagtg ataaaacgat tagaacatta atcacaagac
     3841 tatataaaaa agagattata aaacgataca aatcagaaaa tatttatttt tactcatcaa
     3901 atattaaaga agacgatatt aaaatgaaaa ctgctaaaac ctttcttaat aaactgtatg
     3961 gaggggatat gaaaagttta gtgttgaatt ttgcgaaaaa tgaagaatta aataacaaag
     4021 aaattgaaga attgcgagat attttaaatg atattagtaa aaagtaatta gaggtatgtt
     4081 tcaaacataa tacatatgta aactatgctt gactcttatt aaattagttt tgttaatgac
     4141 atttaaaata tattattaaa gatgagagtg tacagaaaat aaccattttc tgtacactct
     4201 tcttttatgt ctaaataagt aagaattaca taggattatg tgttcaaaaa cccaacaaaa
     4261 aatctatgtt cataaaagac cttgtaatta agttatggta cactgaagat gtatatagga
     4321 ggtttgtatt ttgaaaatag gttatgcaag agtttcaact ggattacaaa atttaaattt
     4381 acaggaggat cgattaaata catatggttg tgaaaagata tttaatgacc atatgagtgg
     4441 ttcaaaaagt aaaagacctg gtttagataa agcaattgaa tttgcgaggt caggagatac
     4501 gattgttgtt tggagattag atagattggg acgtaatatg gaggatttaa tcacattagt
     4561 taatgagctt aacgaacgag gtgtaagttt ccatagttta gaagaaaata taacaatgga
     4621 taaatcaagt tcaactggac aattattatt tcatttattc gcagcatttg cagaatttga
     4681 acgtaattta attttagagc gttcttcagc tggccgaatt gcagcacgtg ctagaggccg
     4741 atatggaggc agaccagaaa aattaaatca aaaagattta aacttactta agacccttta
     4801 tgataatggc acgccaatta agacaattgc agaacagtgg catgtttcac gtacaacaat
     4861 ttatcgttac ctcaataaat tggaggacaa ggaagatgaa aaacaaggag aagtatctaa
     4921 ctaatttttc tgaagccaaa cgtaaaaaag ctactcaaaa gtacaatatt ataaaacctt
     4981 ttatcctagg cgaacaatct ttatcaagta tttctaaaag taaagggatt gcgttaagca
     5041 ccctttatag gtggaataag tcatataaag aacaaggact taaaggacta atctatgcga
     5101 caagagctga taaaggaaca cgtaaaatag aaccaaagat aattgatgaa attgaacgcc
     5161 ttgcgcttat gaataaaaga aatagtatag ccacaattca taggaaaatc actaattact
     5221 gtaaagaaaa taattttgat ataccaagtt ataaacaaat ttatagtgtt attaaagcga
     5281 tgcctaagtc tgttattgat ttctctcatc agggtgaaaa atactatcaa aataagtacg
     5341 atttaataca aattagagaa tcctcgagac ccaatgaaat atggcaagca gaccatactt
     5401 tgctagatat ctttatatta gaccaaaaag gtaatatcaa tagaccatgg ctaactatta
     5461 ttatggatga ctatagtcgt gcaattgcag gctatttctt aagttttgat gccccccaat
     5521 gctcaaaaca cagcattaac actacaccaa gcaatatgga ataaaaatga taccaattgg
     5581 ccagtgtgtg gtatacccga aaaattctac acagatcatg gaagtgactt tacttcacat
     5641 catatggaac aagtcgctat tgatttgaaa attaacttga tgttttcgaa agttggtgtt
     5701 cctcgtggtc gtggaaaaat agaacgattc tttcagacag ttaatcaaac tttcttagaa
     5761 caactgcctg gatatataaa caataatgat actcctagta atctaataaa ttttcacaat
     5821 tttgaagaaa aattacgtta ctttttaatt gaagattata atcaaaaaga acatagtact
     5881 attcatacca cgcctatcag tcattggaat agtaatcact ttttccctaa tatgccaagt
     5941 agcttagaac aacttgattt attattgttg gaaataccta aatctagaaa agttcattca
     6001 gatggcattc attttcaagg ttttcgatac agtaatacta atctagaagc ttatgtaggt
     6061 gaatatgtac tgattcgtta taacccaaat gatatggctg aaatacgtgt gttttataga
     6121 gatgaatttc tttgtactgc tatatgtcca gaaatagctg attactccat agatataaaa
     6181 gacatacagc acgctcgtag tcagagaaga aaacacttaa aacaaaatat tgctagtcca
     6241 agtaccacgg aattaattaa ggaagaaaaa aattgtggtt attcacctca agaaacgact
     6301 aaaaacgtca aaaaattaaa gagatatcgt aatgactaaa aatcaaaatt tcattgaaac
     6361 gaaagagtat aaacgctttg ctgaattttg tgatgcttgt attaaatatc agtatattgg
     6421 tatatgttat ggtcaacctg gtgtcggaaa aactttatcg tctaggtatt acacaaattg
     6481 ggatactatt gaaaaacaag ttaaccatag aggttgggaa gatttagcta gtaaaacgac
     6541 cgatgacata ctatcggtgg ataaaatatt ttataatgca ccagcagaaa aacaaactaa
     6601 attaaggaat gatttatata gtattactgc aatcattgat ttgggtcaaa aattacatgt
     6661 tgtaaataag tatggacatg aacatagtaa acattatagt gatatgttta aatatattga
     6721 tttaattata gtagatgaga ttgatcgcct taaagtgcaa catttagagc aattaagagc
     6781 tatttatgat gaacataatt tagcaatgat atttattggt atgccgggta tagagaaaaa
     6841 actatctcgt tatcctcaac tatattcgcg tataggtttt gcgcatgaat ttgataatct
     6901 aagtaaagat gagacgcatc atatattaga atataagtgg caagacttag gatttgattt
     6961 aaaactcgaa gactttactg attatgaggc aataacgacg attattaaaa ttacaaaagg
     7021 gaattttagg ctgattcatc gtttatttgc gcagatagac agaattatgg atataaatgg
     7081 tttagataaa ataagtacag aagttgtaga aacagctaga gatagtttag ttataggtat
     7141 tcgataatag aaaaagcaac gcattttaat atagtgcgtt gcttttctca tttattaggt
     7201 aaagtcattc tcatatatcg agtaaagtga caacaattat atatgtatga ttagggtgta
     7261 cttatatcat tcatataaat gtttatttat accctcaata aaaatattat atgcttttaa
     7321 gcacctatca cattccttat aaaaatgttt attcaatcct ttaatatcga ctagcgtagt
     7381 cttataattt ttttgtaaca attttaaatc ctcttcgtaa aagcttaatt taaaatgacc
     7441 ggcttgagct aatggctttt ttccttgttt aattaaaatc aatatgtttt ttaaatgttt
     7501 taaaaagttt ttataatcat aaacttttat tttcatgaat gatttatgtg gattattttc
     7561 ataatttagc aggtagtttt ctatatcttc aatataacta tcatcaaatg gtgtgtgctg
     7621 gaaataaaaa gtttttacat acatgaatat tttataaagt tcttctttca aaaaatcata
     7681 tgtatctaaa tctctttgta tagcatccaa tttttttaat ttttttacat ttttaccaca
     7741 atcctgtact cttatccatc cactattttc tttaatttca ctaggtacac tttgcattaa
     7801 agtctgagat actttacttt ttaattccga aatatcatta atatttggac taattagtct
     7861 attttcttta acttttgtct taaactcatc taatttttta gacttttccg cggattcggt
     7921 agatgcttta ttcatctcaa aaacatatat aggtttacct aaagatttag caaaattgta
     7981 ctccatttct gtatagctaa tattttcttc actatcaatt gttccataac tagaacctaa
     8041 caataatatc actgcatctg attcattgat ccattgtgtt attatttccc attggctttt
     8101 actacttgag ttaaaaagtt ccatacctgc tggaatatta ttactgttta aaactgcttc
     8161 tactactgct tgacgctctt ctattaaatc taaataagtt gatgaaataa aaatttgata
     8221 tttaatttta gtattactca tatatgctcc tttaataaaa aatcaattta cataaatata
     8281 tcatatgata atatccaaaa agactactta aaatattatc tttttgcatt cctctactaa
     8341 ccagtgttat aatctagata acgaaaatga ttaacaatta atgcaccaat ccccacacta
     8401 ctgcaatagt gtggggattt tttcgatgct ggcttataaa gtcgcctatt aattatttgt
     8461 tgcgtttact aagccaataa gtataatacg caacagcaca gccactgatg actggtgcta
     8521 tgatgtgaac gaaaatgatt agcaaagtaa tgcacctcct ctctgcgtct gaattgacgc
     8581 ctgagagata ggcgacctgt atattatatc atctccgaat atacgatgat agataacttc
     8641 cgataagtcg tcttatgtta tataactttg ttttttatag tatcaagaca agaagaaact
     8701 cgtttcactc gtttcaaaaa ccctcctgat ttttagagaa aaactctctt atttcatcgt
     8761 ctttaataaa ataatatgcc atctttccat ctttataaaa atcaagtacc tcatttttat
     8821 ataaaagcct taaatgatgt gaagttgaag caacactcat tttcaatatc aaagaaatat
     8881 cacaaacaca caactcatct tctttaatca aagataatat gattttcaat ttcttctcat
     8941 cacaaatttt ttctaaaatg ttaagtaatt tcttagattt atcatcttct aaaaaactta
     9001 aagcattgtt aactttatcc tcatgtacac agatcacatc acaagtattt tcataactca
     9061 tataaaatca caccctaaat taaaatataa atcctaaaat tgtttgaata gtgtcatttt
     9121 caataataat aaataaacct aaagctatat aaatgatagc cataatccaa cgactaaatt
     9181 tctcaacaat ttctccaatt cctgggatat tagctaattt ttgtgcagta aacaccaaga
     9241 agaaaattaa aattaaaaag acaaacagag taagtaataa attagtaaca cttaatgtca
     9301 caaaatacgg aacaaataaa ccaatattat cggcgccaca acttgctatc gtaacaattg
     9361 caaccgtacc aactaattta gacaatcctt tttcattcaa ttctttttta gctctctttt
     9421 ctccttcaca atcatcataa atagccactt taattccaag ataaattggt attaaaccca
     9481 ataaacctaa tatccacttt tctggaacat aatttaatac aaaagctaaa aacaaactaa
     9541 ctaatattaa aataatagac cctaaatatt gaccaacata aatatttcta tattcttttc
     9601 tagtctttgc tctagcaaaa aatattaata aaattactaa taaatcaact gctgtagcaa
     9661 tataaagaac agcagcagca acaaccgttt gaatcataat acacctcatt caaaaatatt
     9721 tttgaatgta ttataactta tatttttaaa taatcatagg tgctttattc caattgcttt
     9781 attgacgttg agcctcggaa cccttaacaa tcccaaaact tgtcgaatgg tcggcttaat
     9841 agctcacgct atgccgacat tcgtctgcaa gtttagttaa gggttcttct caacgcacaa
     9901 taaattttct cggcataaat gcgtgtctat gcgtagacat ggagacactt cagaattatg
     9961 gagtgattac atgagtttaa ctatttttct ttattcagtt ttaggaagtt tattagcaaa
    10021 ttatatctac gaaaaatctt caaaataaat aactttttcg gttctacttt gtacacttta
    10081 tctacctggt agacctaatt gttattgctt tacaggtcta aaattcgtcg ttataatcta
    10141 gttaaatccc gtaagggcgc acttatacgt cggataaatc gacatgtgca aaaacgtaat
    10201 cgaccttcgt cgattttttt atttcaaaat taaagaaacg gcttgagata ttccgagcag
    10261 ttataaaaat taatttgcgt tgaatattgc tactacattc ttgaaaaagt gatgtagatt
    10321 tatagcccat aacttttttg aattacatcg acgatacggc gtcgaaagaa aaagctacct
    10381 cactttatct gggggggctt ttatttttta tgcccttatt ttgaatttta agagggcatt
    10441 ttaaagattt aggggtgatt catatagttt tatatctaaa acttatatac gcttttaaaa
    10501 cgcaaatatg agccaaataa atatatgcta ttttcaaaaa caaaaatttg agcaaaaaca
    10561 ataactattt tttagacact gcccatttac atgcaaatta aaaattagca taaaattctt
    10621 taaaacttcc ccacgttctt ctaaattcct gcagggcttt tcttatcaaa aacttagaaa
    10681 ttttaattta actctaaaat ctccgtaaga gcataaggga aatttgtccc catcaatgaa
    10741 tgggggatct ggcaaagcca gatatttcaa ggcttcgaaa atgtttttgt gtggggtcat
    10801 aaaaagctca agtgtcacac ttttgtgaca ctacatacag catttgtcac aaaaataaga
    10861 cagcactttt tttacaaaaa agtaataaaa aaagacatca gttatcacta atgccttaaa
    10921 taataatttt gcttttcaaa attgccgtaa tcgaatgtgc cttttcttct tcatttgcta
    10981 ttttatcttc atcacttgta ttaattaaat tgccatcttc agcatcgtct aagtttaaaa
    11041 ttttatgttt ttatttaagc aatccaccat aacttaacat acgttttcga tacaaatctt
    11101 tttctagatc actgacaatt tcttgatttt ttcatcgcta tcagttaaaa agtcagatga
    11161 tttaacgaaa tattttgatg tatctttgat tgttataaaa tcatttgaat gattgattaa
    11221 agatattata ttgtttcatg tttttacggc gcatataaag tgcatgtgtt tcttcaaatt
    11281 cagttaaaat tgtttgcatt aaataacctt gcattgactt gaatgattac taatttcatt
    11341 ttcggactct atatcattca agtcattcat atcatttatt tcagtattgt tagattcagt
    11401 atagctaagt tcagtatcat tagattctgt tttatcgact tcttgaagtc ggtttttccg
    11461 acttccttgc cattgctgct ctcaacagtg ttttcttgct tttgaatttt ataaatatca
    11521 tcttctgtta cttctggttt aactaaataa agtttatttg tcttatttaa accttgtctt
    11581 tcttgtagta gtaattcggc ttcaattaag ttctttcttt attttaatta ctttatcttt
    11641 tttacaattt aatatatttt gtgggttttc atttttgtaa taaaaataaa tattacctgt
    11701 tttagaatca acccaaccat ttttaattga taaatctaaa cgatctctaa gaatacccca
    11761 tgccattttt gcatcattgg ataacttgat atatttagga tttgtaaaaa atactttcgg
    11821 tatttgataa aacttttctc tgtattcctc atttatgttg taaagtttaa ttgacataat
    11881 aaaaacctct ttccgaattt tagtttggta agaggtaata aaacgcttac attttttgtg
    11941 tttatttaat aatctaggtg cttgcactaa gatattattc attatataat ctaagtatcg
    12001 aaaattatat aaataaacag tttctaaacg ttttattacc aaaccccgac tattaccagt
    12061 agttggggtt tttgttatat taaggttatt atagcacttt gaataaactt aaaaaaggga
    12121 aaatataggt ttataaacct ttgataaaca ccataaaccc tttacaaacc cttgataaaa
    12181 aggttggcga atttatattt ttatttgtcg attactttat tattaatcgt tataagctta
    12241 taatatttta ctaagggttt ataaacattt tataaagggt tgatgatatg aaaagtgtaa
    12301 aaaggttgag tgaagaatta ggggttagta agcaaacgat ttttaataat attaagagat
    12361 tgaatataga gacaataaaa caggaaaaca cttcgtttat taaagaagat accgatatag
    12421 aaaaaatcat tcaaagagta aatgaaaata aaaagaaata tggttttgaa agtgctactg
    12481 aagacaaaca aaaaaaagag tcggataata ttaattttga atctaaaagc gatgctcaaa
    12541 tagtagaaat acttaaaaat cagattaata ctttaaataa tcaaattgaa aaacaagaaa
    12601 gtcgtcatga aacaacaatt gaattttaca gaaaagagtt gcaagaaaga tcaaaattgc
    12661 ttgagaatca gcaagttctg gcattagaga gtaataaaaa gattcaaaaa ttagaaaatc
    12721 aattagaaaa agaaaaacac cttaattatc cctttgatac atctactaac gctagacaaa
    12781 acgttgatgc acaagaaaaa acatatacta ctagtcctgt aaatattaac cgagatcagg
    12841 aagaaactaa agaaacagag attcaatata aggatatatc tggaagtcaa agcgacgaaa
    12901 gtacacaagg tgaagaagca caaagagaag acgtttcagc taatccaaat gacaatgata
    12961 gtgatataga agaaaagagt gaagaaacgg aacctaaaaa ggggttttgg agtcgtctat
    13021 ttggtaacta attttaatta aaaaggtacg acaagttcat aaattagccg tgctttttta
    13081 tgtgaattga acttctgata atcatcgatt atgttaacca aacaaaaagc cataaatgcc
    13141 tatatgacgg catttatggc tttttacttt cattatcttt tatgcatctt ttatacatcg
    13201 ttgatttgac gcgttttcat tcttttgcat tggcaagtat tttgtatctt tattcagtta
    13261 ctatttcttt tctccaacct aacaaaccat ctttaactct aataatatgt ttgccacgcc
    13321 agacacttct tacttcgaaa taataccatt ccccgttttt gttgaggaaa taaatatctt
    13381 gataaccttc tttaatgaca tattttgtag cttcttgtct ttgatcgcca aacattatca
    13441 atcccaccct tatatttatt tatctttaat atataacaac atttattaat attcatgtta
    13501 tttcatggaa ggagagattt gttataatgt gaaggtcgtc tatctctcag atgtcaattc
    13561 ggcgtagaga ggaggtgcga tttatgaatg aaattcttgt tcacatcatg acaacggcaa
    13621 tcagtggttg tctcgttacg ttatttggtt attagctcca taaacgtgat aaaaaataat
    13681 atagacgatt aaagccaatt caccaaaaaa ccccgaacta cggcgaatag ttcggggttt
    13741 tgtgcgttta caaacgaaat tcttgttact tttagtatat atttcatatt gccttttgta
    13801 aactcttcta ttcttatcaa tacatttcaa ggtgtcgtaa aaatactttc ctttttcata
    13861 ttgcctgatg tgcattaaat tttgatttta aaatcaaccc atgaacgaat gaatggccca
    13921 aactaaaaat ccggcaacag gaaagaaaag ccaccaaaaa tcataaagaa aatcaactat
    13981 ggaaggtacc ctgttactct ctctataatt tccctctaaa ataacttttt taaaacgtgc
    14041 atctccttta attaaatgct ctaaagagat tccgaataaa tcgctcatag caatcaaaat
    14101 atctaaggaa ggatagtttt tggcactttc ccatttagaa acactttgtc tggaaacctt
    14161 taatatattg gctaattcct cttgagacca tccttttaat tctctctgtt cttttatagc
    14221 ttcagctaat ttcataaaat cactccttaa ctcaaactat aattaaaata attgaaaagt
    14281 cacgatactt ttagttaacc aactcgcaac gaaaagttgc gttattccca attcagttca
    14341 agttgtttta aaaaatcctc tcgttctttc tctaattgtg ggtcgtaatc tttttgaggt
    14401 tgcttttcat atgaccgttc ttctaaccat ttaggcgtct tttcacgcct cacatattgt
    14461 cttgatttat ctatcttgga catttgaggt tgtcgtttgt tatgaatgcg tttctcagcg
    14521 tcaaatgtga actctatcca ttcaatttta cgcccttttt tcgctttgat tttattgata
    14581 gtaagattat taaatataga acctaattca ataataatag gtttaaaaac atttttgtta
    14641 atatcagtca tacgataaga tttaggtata tctaaacgat ttttaaaatc atcgatgtga
    14701 atttttaaat agcctgtatg tttgtattgt ttaagtaatc taaacatatt tttagaatat
    14761 gtagatttaa gcctagtcat ttcttttaat tcaaattttg taaaattatt agtaattgaa
    14821 ttcaatatgt gttttaaatt tgaagaagtt gatatttcta gatattgttc tcgcttatgg
    14881 attctataat gattgaataa aacgaatctt tctattacat catcatcttc atatctaatg
    14941 gttaaattca acatcttttt atacacatta tctaaatcat tagcaaatct attaatatta
    15001 cgtgtttctg gactataatt acttaatttt tttaattcat caaaagacaa acgtaatgta
    15061 ttagtatctt gctcttttaa tttattacac atcgcaaaaa ataaattaat ttcagtagct
    15121 gtaaatcgcc ttaatggaac taaattcatt tcatttttat atacaactgt ctctcctgtc
    15181 atgatacagc cccctttatt acgaacctaa aggagtatcg tttgaatata cactcccatt
    15241 tgaaaacttt tattcacaat aaactacttt attatcaatg tcaaaccata aaaggagtac
    15301 aactttttaa aacactcctt ttatgtggca aaaacactcc ttttatgtgg caaaaacact
    15361 ccttttatgt ggcaaaaaca ctcctttagg cattgaaatc ccttgttgct ctagggctga
    15421 acaagcccct aaaaaggttt ttaaaaagat ttataaaaat atattaaaaa gttcgagggg
    15481 ggctacctat ttttcatcct aaaaaataat taacctcaaa caaatgcatt taaatatcta
    15541 tttttataat gtataaccat cttctctatc ttctttaaaa atgatttctc gttcttgtgc
    15601 ttgatatttc ttcttaaaga actgttcatc attgttatct atcgtcatta cttcacgtat
    15661 tttagaattg tctaaatgat tatcaatatg atttattagt gtatgataac gctcttcttt
    15721 catcatactt ttaatgattt taaaaacttg attgaataac ttaagcgtat aatttagttc
    15781 tttatatttc ttttcattct ctgacaacaa ataattataa cgttgtgcta aatcattaaa
    15841 ttcttcaacc agcttttcat tttccatatg gacactagtc aattcattaa ctaaactttc
    15901 attttgtttc tctgcttttt ttaatgactt cccactttta atacattcat aatcatctaa
    15961 tatcatctgt gctgctttaa tttgtttagt gtatttttca aaatcagttt tagtaattac
    16021 aatattgcct gtttcttgct tctctttatg aaaccatcca cctacatttt tagttttaat
    16081 ttcatacatg acactcagaa gctttttaag cgtatctaat gatttttggt agttttgtat
    16141 caatttatca ttttcttgct ttaaataatc ctctatttgc ttctagcgca tatgcatttg
    16201 tttatgatat tctgtttttt gtttataacg gctaacttga tcatgttttt cttttgtaag
    16261 ttgtctagaa attcctcgtt ttaaatcata gccttgctta ttaatatacg tattgaatct
    16321 atcttggaat tcggttaatg cttttttatt acctacaact tctttcgcac ttaaacgtcc
    16381 atctttagta ataggaacta cgccataatg catatgtggt gttatctcat ccatatgtac
    16441 tgtcgcatat aaaagatttt ctttaccgta ttcttcttcc aagaacgctt tagcatgctt
    16501 aaaaaactat tttgtctctt cttcagataa ttgattaaaa aacacattat ctgatgtaat
    16561 taatccatca atatgtttaa tggcatctgt tctaattttg cgtttccctt tataattttt
    16621 ttcgattttc tcatcaattt ttttattaaa atcaaactta gtatcattga ctaaatcata
    16681 gtttaaatat gacttactta aatcaatatc tatattttca taatttttat tttctctttg
    16741 aatatgtctt tgaatacctc ttgtatttgt ttttgatttc actttaacaa ctcgaataat
    16801 tgaataagac ataataaatc aacttccact gcatatgatt ataacaccta aacacagaaa
    16861 agttttaaca tactagactt attaaaaacc aaataagtca ttaaaaacgt gtgctctgcg
    16921 aggcttgttt tttgtcatca taaaaaagga ctggaaaatc cagtccttaa attaaaaaac
    16981 tcaaaagtaa tgactaatca tatttcatat tgttttttct ctatgtatgg ctatacctat
    17041 caatatttct taacttctaa gctcagaaat attgactatg acatcaaatc gtttcgcaag
    17101 ctctaaatca tgcgttacga caatcatagt tttattttca tcaagtagct tcaataataa
    17161 atcaataact atttttccat ttttcgtatc tagtgaccca gtaggttcat cagctaaaat
    17221 gattttcgga tcttttaata ttaatcttgc caatgctact ctttgttgtt caccaccgct
    17281 tagagaacta acaattctct tgatatctaa atctaggccg acctttttta atacttcttt
    17341 ctttaagttc atattatctt ttttattctt tttgaacttt agggctaaat ctaaattttg
    17401 actgattgtt tgattttcaa gtaaagcaaa attttgaaac aaatacccta acgtatatct
    17461 ataaaaatcg actttctttt ttagtaactt atcttcaata tatatgcttc cttgtgatac
    17521 atcttcgaac ccagcgatta tgttaagtaa agtagatttt ccagcgccac tttctccaac
    17581 taaagcatat gattttcctt tttcaaaatt aaagttacat ccgtctaaaa tgtttttatt
    17641 accttttttt acaaaaacat tttcaagttt tatcactatc ggtcacctca ttttaaaaag
    17701 ctaggaatat cttttgtaat gtattctatc gaacgcacat atttcccttt atgatttact
    17761 ttcacatatt cttttgtagg atcataacct aaaaaatcca atttataact ctttttttct
    17821 ccatttttag agtatacagt tatatttcta tagtcctggg tatcttttgg aactttggca
    17881 taagatactt tttcttttaa cagtgggtta aaacgatcta aatgctcatt tctaaccaat
    17941 aacagactaa gtatgatgat taatagtaca attgttacaa taattaaagt tcttttcatt
    18001 gtttaaatct ccctcattaa atctttaaag tatttttcaa gatatttaat ataagcaatt
    18061 tgaagtaaat gttgaataat agcaatagac attattatga atagtaatat ctttgaacca
    18121 aataaaatat gcgtagtgta agctaacata atagaaagta agatagaaat tgttaaataa
    18181 cgtacattac tgctgaataa tgaataacca tgaatttttc ttaataatag ttgcttttta
    18241 ttccagctaa aatattgaat tgtttcaaat acagtagcta tcaaaagaat gaaaacgtta
    18301 ataataatag taactattgt tattatcatt tttgttttcg tttcatttaa ttcatttaac
    18361 acagaatcct tgtaattagt tataccgcta atttcttctt ctaggtgatt atctttaagc
    18421 aactgtttaa gtgtatctaa atctttaaat agatatccac cttgagaaac agcagctaaa
    18481 taaaaatctc ctgttaaatc gtcaagtgtc aacaacatta ctattggaga atctagatac
    18541 ccaaatttca aattagttgt gcgatcaaaa gaaaaaacag atacgttttt tgacagtact
    18601 tgcacatcta cttttttgtt ttgttgcttt tgaaagtcaa tccatccttg gtgatttttt
    18661 tgaatttcag atttttgata ttgtaacctt ggaggaataa atacgtttat tttatccgaa
    18721 tgattgtcaa tcattttaaa atcatgattt atatttttat agaaattcag aaaattgtta
    18781 ttgataaaaa agacattgcc attttcagga atgtaattgt ttttatcggg attggctata
    18841 ttattattct ttaaaagcaa tccaccaagt tgttcgcttt tcttaattaa attgtatata
    18901 ttagtttcta aaatttgttt ttcttctgaa tttctaatat taggagaaat ctctaatgta
    18961 tagtaattat ctaacttttg ccagattttt tcagagtcat atatattctt taacttcgta
    19021 taagcattta aattttgtgc cagtaaaaaa gatagtatta gcaccatgat acatttggtg
    19081 aaggtaccca taaatattga aaacttatat ccttttttcc cttttaagat taatggaata
    19141 cttaacttca aaagaagact atacgaaatc agccacagca atgtagtaat acaagcaaaa
    19201 acaaaaagca acacgataaa tctacgaata aacattaaga aatccaattc taaattggct
    19261 atatgaatga ttaatatatt agcaataaag aaaatagcgg taagtactag ccaataaatg
    19321 atttttatat gaatattatg aaaaataatg cgtgtagttg aaaagccatg tagcttttga
    19381 atagcataaa atttcaaatt atatcctctg tcatataaga agtacaaaag atataatacg
    19441 cctaagaata tgaaaggcac taataaatca ttatctatga ctaattcaaa aaataatatg
    19501 tttctattta tgtattcaac ttcagatgtt aaaccagctt tttttaattc actcgtaagc
    19561 tcttctacat tgaaatgttc accaataata taatactttc cttttatctc tctgtttaat
    19621 aaatctgatg gagttaaaag tgatgtttta ttacgtataa agtcagaatt atttcgtttt
    19681 gagttgaaaa caaaaaattc ttttttatta tcaaaatctt taacggattt aattatttgt
    19741 atattttgat ttttggcgcc tgattcaatg acatctaaca cttttgattt actgttagat
    19801 ttatcccaat tagagattgt taaaatattg gaactttcag gtataatttc ttcattttct
    19861 ttgaagaaaa ataaaaataa tagccctgaa attaataata aagtactaaa atctaaaaat
    19921 aatttgaatt ttttcatatt gcctctttca agagaataga cagaattaag tttacttaat
    19981 tctgtctatt ctccttaatt aatatatgta attagtgaag actataaaat gttttgtttc
    20041 caccccaagc ctttggagca gatgccttag attgaacacc aggtcgagca acaccactaa
    20101 aagatgaata tttccctact gctgttgaac catgatttct tttattgtga ctataataag
    20161 accatacgta atgttttcca ataccatggc tccaaacacc accagctaca tgtactgttg
    20221 cagcttcagc tttataagtt acacctaata aagtgccgaa taagattgta ctagcaatac
    20281 aactagaaac aaatttcttt ttcataaaaa cacctccatt taatattctt tatttattat
    20341 agcaaaaata aataaaatag agaatgagta aaaataatct aaaagtgttt tttctgctct
    20401 gttgcttgtt ttgttcatct atatataata ttaattctat tatccttaaa ttaactatca
    20461 ttaaacaacg atatgacaat gtataataaa tacaatttca ctacctataa ttcaacatta
    20521 tataaactaa agtatttcaa ataattaact gtattaatac tctcatcatg attgcgttat
    20581 aaacgttcgt taatgagaaa aagagagagc atatttacgc tctcttttct tgtcttatta
    20641 ttaaaaactc ataatagatt ataatcatct gttttgagac gctgtgagaa gctctcagtt
    20701 gcattgaa
//
