LOCUS       NZ_CP080002            20653 bp    DNA     circular CON 03-SEP-2023
DEFINITION  Staphylococcus aureus strain A202 plasmid pA202, complete sequence.
ACCESSION   NZ_CP080002
VERSION     NZ_CP080002.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN20294505
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 20653)
  AUTHORS   He,T. and Liu,Y.
  TITLE     Staphylococcus aureus Genome of the plasmid
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 20653)
  AUTHORS   He,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-JUL-2021) College of Animal Medicine, Xinjiang
            Agricultural University, No. 311 East Nongda Road, Bayi Street,
            Urumqi, Xinjiang 843000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: other plasmidid v. 1.6.5
            Genome Representation             :: Partial
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 09/02/2023 04:14:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 25
            CDSs (total)                      :: 25
            Genes (coding)                    :: 21
            CDSs (with protein)               :: 21
            Genes (RNA)                       :: 0
            tRNAs                             :: 0
            ncRNAs                            :: 0
            Pseudo Genes (total)              :: 4
            CDSs (without protein)            :: 4
            Pseudo Genes (ambiguous residues) :: 0 of 4
            Pseudo Genes (frameshifted)       :: 3 of 4
            Pseudo Genes (incomplete)         :: 1 of 4
            Pseudo Genes (internal stop)      :: 2 of 4
            Pseudo Genes (multiple problems)  :: 1 of 4
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP080002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..20653
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="A202"
                     /host="cattle or sheep"
                     /db_xref="taxon:1280"
                     /plasmid="pA202"
                     /geo_loc_name="China:Kurle"
                     /collection_date="2018-09"
     gene            join(19703..20653,1..24)
                     /locus_tag="KZO19_RS00005"
                     /old_locus_tag="KZO19_00005"
     CDS             join(19703..20653,1..24)
                     /locus_tag="KZO19_RS00005"
                     /old_locus_tag="KZO19_00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="WP_000072390.1"
                     /translation="MSNTKIKYQIFISSTYLDLIEERQAVVEAVLNSNNIPAGMELFNS
                     SSKSQWEIITQWINESDAVILLLGSSYGTIDSEENISYTEMEYNFAKSLGKPIYVFEMN
                     KASTESAEKSKKLDEFKTKVKENRLISPNINDISELKSKVSQTLMQSVPSEIKENSGWI
                     RVQDCGKNVKKLKKLDAIQRDLDTYDFLKEELYKIFMYVKTFYFQHTPFDDSYIEDIEN
                     YLLNYENNPHKSFMKIKVYDYKNFLKHLKNILILIKQGKKPLAQAGHFKLSFYEEDLKL
                     LQKNYKATLVDIKGLNKHFYKECDRCLKAYNIFIEGINKHLYE"
                     /name="DUF4062 domain-containing protein"
     gene            complement(144..959)
                     /locus_tag="KZO19_RS00010"
                     /old_locus_tag="KZO19_00010"
     CDS             complement(144..959)
                     /locus_tag="KZO19_RS00010"
                     /old_locus_tag="KZO19_00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000164958.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYNAPAEKQTKLRNDLYSITAIIDL
                     GQKLHVVNKYGHEHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            complement(952..2395)
                     /locus_tag="KZO19_RS00015"
                     /old_locus_tag="KZO19_00015"
                     /pseudo=""
     CDS             complement(952..2395)
                     /locus_tag="KZO19_RS00015"
                     /old_locus_tag="KZO19_00015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /name="DDE-type integrase/transposase/recombinase"
     gene            complement(2367..2960)
                     /locus_tag="KZO19_RS00020"
                     /old_locus_tag="KZO19_00020"
     CDS             complement(2367..2960)
                     /locus_tag="KZO19_RS00020"
                     /old_locus_tag="KZO19_00020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690638.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            complement(3224..3604)
                     /gene="blaI"
                     /locus_tag="KZO19_RS00025"
                     /old_locus_tag="KZO19_00025"
     ARG             complement(3228..3604)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            complement(3594..5351)
                     /gene="blaR1"
                     /locus_tag="KZO19_RS00030"
                     /old_locus_tag="KZO19_00030"
     ARG             complement(3598..5351)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.56"
                     /coverage="100.0"
     gene            5458..6303
                     /gene="blaZ"
                     /locus_tag="KZO19_RS00035"
                     /old_locus_tag="KZO19_00035"
     ARG             5459..6300
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            6672..7205
                     /locus_tag="KZO19_RS00040"
                     /old_locus_tag="KZO19_00040"
     CDS             6672..7205
                     /locus_tag="KZO19_RS00040"
                     /old_locus_tag="KZO19_00040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823239.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001823239.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGKSIENRPV
                     LQEALNFLRMGDRFVVESIDCLGRNYDEVVGNPLLDKFMKDLIIQILAMVSEQERNESK
                     RRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRIIYHRVVEMLEEGQSISKIAKEVNIT
                     RQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            7619..7912
                     /locus_tag="KZO19_RS00045"
                     /old_locus_tag="KZO19_00045"
     CDS             7619..7912
                     /locus_tag="KZO19_RS00045"
                     /old_locus_tag="KZO19_00045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WP_000726502.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            7987..9921
                     /locus_tag="KZO19_RS00050"
                     /old_locus_tag="KZO19_00050"
     CDS             7987..9921
                     /locus_tag="KZO19_RS00050"
                     /old_locus_tag="KZO19_00050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WP_000713729.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTAIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLILKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTLDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            9925..10236
                     /locus_tag="KZO19_RS00055"
                     /old_locus_tag="KZO19_00055"
     CDS             9925..10236
                     /locus_tag="KZO19_RS00055"
                     /old_locus_tag="KZO19_00055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WP_000831610.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            10248..10874
                     /locus_tag="KZO19_RS00060"
                     /old_locus_tag="KZO19_00060"
     CDS             10248..10874
                     /locus_tag="KZO19_RS00060"
                     /old_locus_tag="KZO19_00060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000593103.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            11112..11741
                     /gene="mobV"
                     /locus_tag="KZO19_RS00130"
                     /pseudo=""
     CDS             11112..11741
                     /gene="mobV"
                     /locus_tag="KZO19_RS00130"
                     /inference="COORDINATES: protein motif:HMM:NF013258.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            11835..12380
                     /locus_tag="KZO19_RS00075"
                     /old_locus_tag="KZO19_00075"
     CDS             11835..12380
                     /locus_tag="KZO19_RS00075"
                     /old_locus_tag="KZO19_00075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001805533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000273005.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTDFEKYTKQIKAAQMILD
                     DYECIKSGKSLKKAEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQEREIIFKEDREDGYTL"
                     /name="hypothetical protein"
     gene            complement(12422..12706)
                     /locus_tag="KZO19_RS00080"
                     /old_locus_tag="KZO19_00080"
     CDS             complement(12422..12706)
                     /locus_tag="KZO19_RS00080"
                     /old_locus_tag="KZO19_00080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001793642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001793642.1"
                     /translation="MKTFIHNKLLYYQCQTIKGVQLFKTLLLCGKNTPFMWQKHSFYVA
                     KTLLLCGKNTPLGIEIPCCSRAEQAPKKVFKKIYKNILKSSRGATYFSS"
                     /name="hypothetical protein"
     gene            12764..13624
                     /locus_tag="KZO19_RS00085"
                     /old_locus_tag="KZO19_00085"
     CDS             12764..13624
                     /locus_tag="KZO19_RS00085"
                     /old_locus_tag="KZO19_00085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000145511.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            13711..14052
                     /locus_tag="KZO19_RS00090"
                     /old_locus_tag="KZO19_00090"
     CDS             13711..14052
                     /locus_tag="KZO19_RS00090"
                     /old_locus_tag="KZO19_00090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000761341.1"
                     /translation="MKLAEAIKEQRELKGWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRVPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(14291..14362)
                     /locus_tag="KZO19_RS00095"
                     /old_locus_tag="KZO19_00095"
     CDS             complement(14291..14362)
                     /locus_tag="KZO19_RS00095"
                     /old_locus_tag="KZO19_00095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_106873653.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGY"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            14511..14696
                     /locus_tag="KZO19_RS00100"
                     /old_locus_tag="KZO19_00100"
     CDS             14511..14696
                     /locus_tag="KZO19_RS00100"
                     /old_locus_tag="KZO19_00100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466619.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSVWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            complement(14915..15658)
                     /locus_tag="KZO19_RS00105"
                     /old_locus_tag="KZO19_00105"
     CDS             complement(14915..15658)
                     /locus_tag="KZO19_RS00105"
                     /old_locus_tag="KZO19_00105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843757.1"
                     /translation="MKSVKRLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESATEDKQKKESDNINFESKSDAQIVEILKNQINTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNAR
                     QNVDAQEKTYTTSPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAQREDVSANPND
                     NDSDIEEKSEETEAKKGFWSRLFGN"
                     /name="DUF536 domain-containing protein"
     gene            16069..16745
                     /locus_tag="KZO19_RS00110"
                     /old_locus_tag="KZO19_00110"
                     /pseudo=""
     CDS             16069..16745
                     /locus_tag="KZO19_RS00110"
                     /old_locus_tag="KZO19_00110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            <16756..17038
                     /locus_tag="KZO19_RS00135"
                     /pseudo=""
     CDS             <16756..17038
                     /locus_tag="KZO19_RS00135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            18247..18864
                     /gene="cadD"
                     /locus_tag="KZO19_RS00115"
                     /old_locus_tag="KZO19_00115"
     ARG             18248..18861
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="99.51"
                     /coverage="100.0"
     gene            18883..19230
                     /locus_tag="KZO19_RS00120"
                     /old_locus_tag="KZO19_00120"
     CDS             18883..19230
                     /locus_tag="KZO19_RS00120"
                     /old_locus_tag="KZO19_00120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119691.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNQEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            19399..19491
                     /locus_tag="KZO19_RS00125"
                     /old_locus_tag="KZO19_00125"
     CDS             19399..19491
                     /locus_tag="KZO19_RS00125"
                     /old_locus_tag="KZO19_00125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     ARG             5459..6303
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     BGC             2619..12912
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          17096..17243
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.333"
                     /coverage="100.0"
                     /evalue="2.96e-25"
     Typing          12765..13624
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(14916..15658)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          11113..11387
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="94.565"
                     /coverage="100.0"
                     /evalue="4.71e-46"
ORIGIN
        1 ataaataaac atttatatga atgatataag tacaccctaa tcatacatat ataattgttg
       61 tcactttact cgatatatga gaatgacttt acctaataaa tgagaaaagc aacgcactat
      121 attaaaatgc gttgcttttt ctattatcga atacctataa ctaaactatc tctagctgtt
      181 tctacaactt ctgtacttat tttatctaaa ccatttatat ccataattct gtctatctgc
      241 gcaaataaac gatgaatcag cctaaaattc ccttttgtaa ttttaataat cgtcgttatt
      301 gcctcataat cagtaaagtc ttcgagtttt aaatcaaatc ctaagtcttg ccacttatat
      361 tctaatatat gatgcgtctc atctttactt agattatcaa attcatgcgc aaaacctata
      421 cgcgaatata gttgaggata acgagatagt tttttctcta tacccggcat accaataaat
      481 atcattgcta aattatgttc atcataaata gctcttaatt gctctaaatg ttgcacttta
      541 aggcgatcaa tctcatctac tataattaaa tcaatatatt taaacatatc actataatgt
      601 ttactatgtt catgtccata cttatttaca acatgtaatt tttgacccaa atcaatgatt
      661 gcagtaatac tatataaatc attccttaat ttagtttgtt tttctgctgg tgcattataa
      721 aatattttat ccaccgatag tatgtcatcg gtcgttttac tagctaaatc ttcccaacct
      781 ctatggttaa cttgtttttc aatagtatcc caatttgtgt aatacctaga cgataaagtt
      841 tttccgacac caggttgacc ataacatata ccaatatact gatatttaat acaagcatca
      901 caaaattcag caaagcgttt atactctttc gtttcaatga aattttgatt tttagtcatt
      961 acgatatctc tttaattttt tgacgttttt agtcgtttct tgaggtgaat aaccacaatt
     1021 tttttcttcc ttaattaatt ccgtggtact tggactagca atattttgtt ttaagtgttt
     1081 tcttctctga ctacgagcgt gctgtatgtc ttttatatct atggagtaat cagctatttc
     1141 tggacatata gcagtacaaa gaaattcatc tctataaaac acacgtattt cagccatatc
     1201 atttgggtta taacgaatca gtacatattc acctacataa gcttctagat tagtattact
     1261 gtatcgaaaa ccttgaaaat gaatgccatc tgaatgaact tttctagatt taggtatttc
     1321 caacaataat aaatcaagtt gttctaagct acttggcata ttagggaaaa agtgattact
     1381 attccaatga ctgataggcg tggtatgaat agtactatgt tctttttgat tataatcttc
     1441 aattaaaaag taacgtaatt tttcttcaaa attgtgaaaa tttattagat tactaggagt
     1501 atcattattg tttatatatc caggcagttg ttctaagaaa gtttgattaa ctgtctgaaa
     1561 gaatcgttct atttttccac gaccacgagg aacaccaact ttcgaaaaca tcaagttaat
     1621 tttcaaatca atagcgactt gttccatatg atgtgaagta aagtcacttc catgatctgt
     1681 gtagaatttt tcgggtatac cacacactgg ccaattggta tcatttttat tccatattgc
     1741 ttggtgtagt gttaatgctg tgttttgagc attggggggc atcaaaactt aagaaatagc
     1801 ctgcaattgc acgactatag tcatccataa taatagttag ccatggtcta ttgatattac
     1861 ctttttggtc taatataaag atatctagca aagtatggtc tgcttgccat atttcattgg
     1921 gtctcgagga ttctctaatt tgtattaaat cgtacttatt ttgatagtat ttttcaccct
     1981 gatgagagaa atcaataaca gacttaggca tcgctttaat aacactataa atttgtttat
     2041 aacttggtat atcaaaatta ttttctttac agtaattagt gattttccta tgaattgtgg
     2101 ctatactatt tcttttattc ataagcgcaa ggcgttcaat ttcatcaatt atctttggtt
     2161 ctattttacg tgttccttta tcagctcttg tcgcatagat tagtccttta agtccttgtt
     2221 ctttatatga cttattccac ctataaaggg tgcttaacgc aatcccttta cttttagaaa
     2281 tacttgataa agattgttcg cctaggataa aaggttttat aatattgtac ttttgagtag
     2341 cttttttacg tttggcttca gaaaaattag ttagatactt ctccttgttt ttcatcttcc
     2401 ttgtcctcca atttattgag gtaacgataa attgttgtac gtgaaacatg ccactgttct
     2461 gcaattgtct taattggcgt gccattatca taaagggtct taagtaagtt taaatctttt
     2521 tgatttaatt tttctggtct gcctccatat cggcctctag cacgtgctgc aattcggcca
     2581 gctgaagaac gctctaaaat taaattacgt tcaaattctg caaatgctgc gaataaatga
     2641 aataataatt gtccagttga acttgattta tccattgtta tattttcttc taaactatgg
     2701 aaacttacac ctcgttcgtt aagctcatta actaatgtga ttaaatcctc catattacgt
     2761 cccaatctat ctaatctcca aacaacaatc gtatctcctg acctcgcaaa ttcaattgct
     2821 ttatctaaac caggtctttt actttttgaa ccactcatat ggtcattaaa tatcttttca
     2881 caaccatatg tatttaatcg atcctcctgt aaatttaaat tttgtaatcc agttgaaact
     2941 cttgcataac ctattttcaa aatacaaacc tcctatatac atcttcagtg taccataact
     3001 taattacaag gtcttttatg aacatagatt ttttgttggg tttttgaaca cataatccta
     3061 tgtaattctt acttatttag acataaaaga agagtgtaca gaaaatggtt attttctgta
     3121 cactctcatc tttaataata tattttaaat gtcattaaca aaactaattt aataagagtc
     3181 aagcatagtt tacatatgta ttatgtttga aacatacctc taattacttt ttactaatat
     3241 catttaaaat atctcgcaat tcttcaattt ctttgttatt taattcttca tttttcgcaa
     3301 aattcaacac taaacttttc atatcccctc catacagttt attaagaaag gttttagcag
     3361 ttttcatttt aatatcgtct tctttaatat ttgatgagta aaaataaata ttttctgatt
     3421 tgtatcgttt tataatctct tttttatata gtcttgtgat taatgttcta atcgttttat
     3481 cactaacttc tttatatttt tgaatttcaa ctacaatttc attagctgat actgattttt
     3541 tatcccatat tatattcata acatcccatt cagccataga tatttcaact tgcttattgg
     3601 ccatttaaaa cacccattcc ttttaatatt ttttcactta ttaattcagc atttttccca
     3661 gacgggtttc catctgataa atgtgtagca aaataatact tatcatgatt tgtaattacg
     3721 taacctacaa accacccatt attatacttc ccgtttacta tacctgtacc tgttttccca
     3781 tacagttcat acttttcatt tttcttaatc aataatgaag aagataattg attctttgct
     3841 tttttactaa aatggttatt ttgttccatc atatttttaa aaactattac ttgttcaaga
     3901 ttagatattt tcaaactatc ttccatccaa tagcttttat aacttcccaa attttcatta
     3961 ccataattta attgcttgag ttgagccgca gtatagttct ttggtatttg attactaata
     4021 cgttcgaagt accaattaac tgaattttgc attgctgtat ttaaatcttg ttccttattc
     4081 caagactcga aaagataatg tttatgattc catgacatac gtgaattttt atcacttata
     4141 atatgacggt caagtccaaa cagtgctaaa taaattttgt aagttgaatc aggagaatat
     4201 ctttttctac tttctttttc attataaata tagtatttgt ctttcttcat gctgtacata
     4261 acgaaagatc cactatttga accaaaattt ttactttcat ctaaaatttg gtaatcgctt
     4321 tgtaagggct ttttataatt ataatcagtt aaggattgcc ccattaaaaa ctggctttga
     4381 attatcatga taaaaaaagt aaaaatacaa ataaaaatta gaattaattt tgactgcttt
     4441 ttcagatcgg cttcttttat attaattaat ctatttttga gtaatgattt tttaccatta
     4501 aatgaatggc ttaatatatt tttgttgaaa aatgaggttt ttaatacgga gtccataata
     4561 gattccgcat aagttttaaa ttcatttttg ttaatattat taaggacaaa tctatcggct
     4621 tctacttcat tgtcatgaat tatctttctt tttacaatat gtactaatgg attgtaactc
     4681 ataataatag agaagatatt aaagataatt aaatgtaaag tatctctatt tttagcatga
     4741 gcatattcat gcagtattat atattttagt cttttatcaa ttacactttt aaaatatgaa
     4801 ctaggaatca aaataatata tttcccatac caaaaagtta ttggagattg aatagcctct
     4861 gcttttcgaa tcacaatatt ttttttatat tgatggttga aaagtatcgt atctatttta
     4921 tttttttcat tttcgtttag ataaagtgac tgtttcttta aatatttaag atataataag
     4981 gctttcaaaa atttaaaact taaaataata actaaaacta tccaaataac tgtgcagata
     5041 ttatcaattg aatcccaatt aaacttatgg atatctgttg cgaactcttg aacaggtttg
     5101 gtggtaatta tgttatggtt caagtcgtgt gacttacttt caactgtggg cgcttgatta
     5161 ttcacattat taaattttat aaaagagaat ttaattggga taaaaggaat taatccagca
     5221 agcacagtta gataccaaac tttataattt aaactataat taaaatagcg ttttaatatg
     5281 tacctaaaaa atactaacaa tagaaatata aaacaaaagc ttactacact cattattagt
     5341 aatttagcca ttttgacacc ttctttcaaa tatttataat aaacaattga catcaatatt
     5401 acaattgtaa tattattgtt ttgtaaaaat tacaactgta atatcggagg gtttattttg
     5461 aaaaagttaa tatttttaat tgtaatggct ttagttttaa gtgcatgtaa ttcaaacagt
     5521 tcacatgcca aagagttaaa tgatttagaa aaaaaatata atgctcatat tggtgtttat
     5581 gctttagata ctaaaagtgg taaggaagta aaatttaatt cagataagag atttgcctat
     5641 gcttcgactt caaaagcgat aaatagtgct attttgttag aacaagtacc ttataataag
     5701 ttaaataaaa aagtacatat taacaaagat gatatagttg cttattctcc tattttagaa
     5761 aaatatgtag gaaaagacat cactttaaaa gaacttattg aggcttcaat gacatatagt
     5821 gataatacag caaacaataa aattataaaa gaaatcggtg gaatcaaaaa agttaaacaa
     5881 cgtctaaaag aactaggaga taaagtaaca aatccagtta gatatgagat agaattaaat
     5941 tactattcgc caaagagcaa aaaagatact tcaacgcctg ctgctttcgg caagacttta
     6001 aataaactta tcgcaaatgg aaaattaagc aaaaaaaata aaaatttctt acttgattta
     6061 atgtttaata ataaaaacgg agacacttta attaaagatg gtgttccaaa agactataag
     6121 gttgctgata aaagtggtca agcaataaca tatgcttcta gaaatgatgt tgcttttgtt
     6181 tatcctaagg gccaatctga acctattgtt ttagtcattt ttacgaataa agacaataaa
     6241 agtgataagc caaatgataa gttgataagt gaaaccgcca agagtgtaat gaaggaattt
     6301 taatattcta aatgcataat aaatactgat aacatcttat agtttgtatt atattttcta
     6361 ttatcgttga catgtataat tttgatatca aaacctgatt ttccctttat tattttcgag
     6421 atttattttc ttaattctct ttaacaaact agaaatattg tatatacaaa aaatcataaa
     6481 taatagatga atagtttaat tataggtgtt catcaatcga aaaagcaacg tatcttattt
     6541 aaagtgcgtt gcttttttct catttataag gttaaataat tctcatatat caagcaaagt
     6601 gacataattg ttgaatttat agtaactgaa acgtatgatt agggtgtata ttaattatga
     6661 gatggaaatc aatgattgtt ggctatgcga gagtatcatc gaacgatcaa aatttagaaa
     6721 gacaacttga aaatttaaag acgttttgtg ctgaaaaaat atttacagaa aaacagtctg
     6781 ggaaatctat tgaaaataga ccagtacttc aagaagcact taactttttg aggatgggag
     6841 atcggtttgt agtagaatcc attgattgtt taggtcgtaa ttatgatgaa gtggttggca
     6901 atccattact ggataagttt atgaaagatt taattattca aatattagca atggtttcag
     6961 aacaagagag aaatgaaagt aaacgtcgac aagcgcaagg aattcaagtt gcgaaggaaa
     7021 aaggcgtata taaagggcgc cccttacttt attcaccaaa tgctaaagat ccacagaaac
     7081 gtattattta tcatcgcgtt gtagaaatgt tagaagaagg ccaatcaatt agtaaaattg
     7141 cgaaagaagt aaatataaca aggcagacga tttacagaat taaaaacgat aatgatttga
     7201 tttaataaac tttgtttcaa tgcaactgag agcttctcac agcgtctcaa aacagatgat
     7261 tataatctat tatgagtttt taataataag acaagaaaag agagcgtaaa tatgctctct
     7321 ctttttctca ttaacgaacg tttataacgc aatcatgatg agagtattaa tacagttaat
     7381 tatttgaaat actttagttt atataatgtt gaattatagg tagtgaaatt gtatttatta
     7441 tacattgtca tatcgttgtt taatgatagt taatttaagg ataatagaat taatattata
     7501 tatagatgaa caaaacaagc aacagagcag aaaaaacact tttagattat ttttactcat
     7561 tctctatttt atttattttc gctataataa ataaagaata ttaaatggag gtgtttttat
     7621 gaaaaagaaa tttgtttcta gttgtattgc tagtacaatc ttattcggca ctttattagg
     7681 tgtaacttat aaagctgaag ctgcaacagt acatgtagct ggtggtgttt ggagccatgg
     7741 tattggaaaa cattacgtat ggtcttatta tagtcacaat aaaagaaatc atggttcaac
     7801 agcagtaggg aaatattcat cttttagtgg tgttgctcga cctggtgttc aatctaaggc
     7861 atctgctcca aaggcttggg gtggaaacaa aacattttat agtcttcact aattacatat
     7921 attaattaag gagaatagac agaattaagt aaacttaatt ctgtctattc tcttgaaaga
     7981 ggcaatatga aaaaattcaa attattttta gattttagta ctttattatt aatttcaggg
     8041 ctattatttt tatttttctt caaagaaaat gaagaaatta tacctgaaag ttccaatatt
     8101 ttaacaatct ctaattggga taaatctaac agtaaatcaa aagtgttaga tgtcattgaa
     8161 tcaggcgcca aaaatcaaaa tatacaaata attaaatccg ttaaagattt tgataataaa
     8221 aaagaatttt ttgttttcaa ctcaaaacga aataattctg actttatacg taataaaaca
     8281 tcacttttaa ctccatcaga tttattaaac agagagataa aaggaaagta ttatattatt
     8341 ggtgaacatt tcaatgtaga agagcttacg agtgaattaa aaaaagctgg tttaacatct
     8401 gaagttgaat acataaatag aaacatatta ttttttgaat tagtcataga taatgattta
     8461 ttagtgcctt tcatattctt aggcgtatta tatcttttgt acttcttata tgacagagga
     8521 tataatttga aattttatgc tattcaaaag ctacatggct tttcaactac acgcattatt
     8581 tttcataata ttcatataaa aatcatttat tggctagtac ttaccgctat tttctttatt
     8641 gctaatatat taatcattca tatagccaat ttagaattgg atttcttaat gtttattcgt
     8701 agatttatcg tgttgctttt tgtttttgct tgtattacta cattgctgtg gctgatttcg
     8761 tatagtcttc ttttgaagtt aagtattcca ttaatcttaa aagggaaaaa aggatataag
     8821 ttttcaatat ttatgggtac cttcaccaaa tgtatcatgg tgctaatact atctttttta
     8881 ctggcacaaa atttaaatgc ttatacgaag ttaaagaata tatatgactc tgaaaaaatc
     8941 tggcaaaagt tagataatta ctatacatta gagatttctc ctaatattag aaattcagaa
     9001 gaaaaacaaa ttttagaaac taatatatac aatttaatta agaaaagcga acaacttggt
     9061 ggattgcttt taaagaataa taatatagcc aatcccgata aaaacaatta cattcctgaa
     9121 aatggcaatg tcttttttat caataacaat tttctgaatt tctataaaaa tataaatcat
     9181 gattttaaaa tgattgacaa tcattcggat aaaataaacg tgtttattcc tccaaggtta
     9241 caatatcaaa aatctgaaat tcaaaaaaat caccaaggat ggattgactt tcaaaagcaa
     9301 caaaacaaaa aagtagatgt gcaagtactg tcaaaaaacg tatctgtttt ttcttttgat
     9361 cgcacaacta atttgaaatt tgggtatcta gattctccaa tagtaatgtt gttgacactt
     9421 gacgatttaa caggagattt ttatttagct gctgtttctc aaggtggata tctatttaaa
     9481 gatttagata cacttaaaca gttgcttaaa gataatcacc tagaagaaga aattagcggt
     9541 ataactaatt acaaggattc tgtgttaaat gaattaaatg aaacgaaaac aaaaatgata
     9601 ataacaatag ttactattat tattaacgtt ttcattcttt tgatagctac tgtatttgaa
     9661 acaattcaat attttagctg gaataaaaag caactattat taagaaaaat tcatggttat
     9721 tcattattca gcagtaatgt acgttattta acaatttcta tcttactttc tattatgtta
     9781 gcttacacta cgcatatttt atttggttca aagatattac tattcataat aatgtctatt
     9841 gctattattc aacatttact tcaaattgct tatattaaat atcttgaaaa atactttaaa
     9901 gatttaatga gggagattta aacaatgaaa agaactttaa ttattgtaac aattgtacta
     9961 ttaatcatca tacttagtct gttattggtt agaaatgagc atttagatcg ttttaaccca
    10021 ctgttaaaag aaaaagtatc ttatgccaaa gttccaaaag atacccagga ctatagaaat
    10081 ataactgtat actctaaaaa tggagaaaaa aagagttata aattggattt tttaggttat
    10141 gatcctacaa aagaatatgt gaaagtaaat cataaaggga aatatgtgcg ttcgatagaa
    10201 tacattacaa aagatattcc tagcttttta aaatgaggtg accgatagtg ataaaacttg
    10261 aaaatgtttt tgtaaaaaaa ggtaataaaa acattttaga cggatgtaac tttaattttg
    10321 aaaaaggaaa atcatatgct ttagttggag aaagtggcgc tggaaaatct actttactta
    10381 acataatcgc tgggttcgaa gatgtatcac aaggaagcat atatattgaa gataagttac
    10441 taaaaaagaa agtcgatttt tatagatata cgttagggta tttgtttcaa aattttgctt
    10501 tacttgaaaa tcaaacaatc agtcaaaatt tagatttagc cctaaagttc aaaaagaata
    10561 aaaaagataa tatgaactta aagaaagaag tattaaaaaa ggtcggccta gatttagata
    10621 tcaagagaat tgttagttct ctaagcggtg gtgaacaaca aagagtagca ttggcaagat
    10681 taatattaaa agatccgaaa atcattttag ctgatgaacc tactgggtca ctagatacga
    10741 aaaatggaaa aatagttatt gatttattat tgaagctact tgatgaaaat aaaactatga
    10801 ttgtcgtaac gcatgattta gagcttgcga aacgatttga tgtcatagtc aatatttctg
    10861 agcttagaag ttaagaaata ttgataggta tagccataca tagagaaaaa acaatatgaa
    10921 atatgattag tcattacttt tgagtttttt aatttaagga ctggattttc cagtcctttt
    10981 ttatgatgac aaaaaacaag cctcgcagag cacacgtttt taatgactta tttggttttt
    11041 aataagtcta gtatgttaaa acttttctgt gtttaggtgt tataatcata tgcagtggaa
    11101 gttgatttat tatgtcttat tcaattattc gagttgttaa agtgaaatca aaaacaaata
    11161 caagaggtat tcaaagacat attcaaagag aaaataaaaa ttatgaaaat atagatattg
    11221 atttaagtaa gtcatattta aactatgatt tagtcaatga tactaagttt gattttaata
    11281 aaaaaattga tgagaaaatc gaaaaaaatt ataaagggaa acgcaaaatt agaacagatg
    11341 ccattaaaca tattgatgga ttaattacat cagataatgt gttttttaat caattatctg
    11401 aagaagagac aaaatagttt tttaagcatg ctaaagcgtt cttggaagaa gaatacggta
    11461 aagaaaatct tttatatgcg acagtacata tggatgagat aacaccacat atgcattatg
    11521 gcgtagttcc tattactaaa gatggacgtt taagtgcgaa agaagttgta ggtaataaaa
    11581 aagcattaac cgaattccaa gatagattca atacgtatat taataagcaa ggctatgatt
    11641 taaaacgagg aatttctaga caacttacaa aagaaaaaca tgatcaagtt agccgttata
    11701 aacaaaaaac agaatatcat aaacaaatgc atatgcgcta gaagcaaata gaggattatt
    11761 taaagcaaga aaatgataaa ttgatacaaa actaccaaaa atcattagat acgcttaaaa
    11821 agcttctgag tgtcatgtat gaaattaaaa ctaaaaatgt aggtggatgg tttcataaag
    11881 agaagcaaga aacaggcaat attgtaatta ctaaaactga ttttgaaaaa tacactaaac
    11941 aaattaaagc agcacagatg atattagatg attatgaatg tattaaaagt gggaagtcat
    12001 taaaaaaagc agagaaacaa aatgaaagtt tagttaatga attgactagt gtccatatgg
    12061 aaaatgaaaa gctggttgaa gaatttaatg atttagcaca acgttataat tatttgttgt
    12121 cagagaatga aaagaaagat aaagaactaa attatacgct taagttattc aatcaagttt
    12181 ttaaaatcat taaaagtatg atgaaagaag agcgttatca tacactaata aatcatattg
    12241 ataatcattt agacaattct aaaatacgtg aagtaatgac gatagataac aatgatgaac
    12301 agttctttaa gaagaaatat caagcacaag aacgagaaat catttttaaa gaagatagag
    12361 aagatggtta tacattataa aaatagatat ttaaatgcat ttgtttgagg ttaattattt
    12421 tttaggatga aaaataggta gcccccctcg aactttttaa tatattttta taaatctttt
    12481 taaaaacctt tttaggggct tgttcagccc tagagcaaca agggatttca atgcctaaag
    12541 gagtgttttt gccacataaa aggagtgttt ttgccacata aaaggagtgt ttttgccaca
    12601 taaaaggagt gtttttgcca cataaaagga gtgttttaaa aagttgtact ccttttatgg
    12661 tttgacattg ataataaagt agtttattgt gaataaaagt tttcaaatgg gagtgtatat
    12721 tcaaacgata ctcctttagg ttcgtaataa agggggctgt atcatgacag gagagacagt
    12781 tgtatataaa aatgaaatga atttagttcc attaaggcga tttacagcta ctgaaattaa
    12841 tttatttttt gcgatgtgta ataaattaaa agagcaagat actaatacat tacgtttgtc
    12901 ttttgatgaa ttaaaaaaat taagtaatta tagtccagaa acacgtaata ttaatagatt
    12961 tgctaatgat ttagataatg tgtataaaaa gatgttgaat ttaaccatta gatatgaaga
    13021 tgatgatgta atagaaagat tcgttttatt caatcattat agaatccata agcgagaaca
    13081 atatctagaa atatcaactt cttcaaattt aaaacacata ttgaattcaa ttactaataa
    13141 ttttacaaaa tttgaattaa aagaaatgac taggcttaaa tctacatatt ctaaaaatat
    13201 gtttagatta cttaaacaat acaaacatac aggctattta aaaattcaca tcgatgattt
    13261 taaaaatcgt ttagatatac ctaaatctta tcgtatgact gatattaaca aaaatgtttt
    13321 taaacctatt attattgaat taggttctat atttaataat cttactatca ataaaatcaa
    13381 agcgaaaaaa gggcgtaaaa ttgaatggat agagttcaca tttgacgctg agaaacgcat
    13441 tcataacaaa cgacaacctc aaatgtccaa gatagataaa tcaagacaat atgtgaggcg
    13501 tgaaaagacg cctaaatggt tagaagaacg gtcatatgaa aagcaacctc aaaaagatta
    13561 cgacccacaa ttagagaaag aacgagagga ttttttaaaa caacttgaac tgaattggga
    13621 ataacgcaac ttttcgttgc gagttggtta actaaaagta tcgtgacttt tcaattattt
    13681 taattatagt ttgagttaag gagtgatttt atgaaattag ctgaagctat aaaagaacag
    13741 agagaattaa aaggatggtc tcaagaggaa ttagccaata tattaaaggt ttccagacaa
    13801 agtgtttcta aatgggaaag tgccaaaaac tatccttcct tagatatttt gattgctatg
    13861 agcgatttat tcggaatctc tttagagcat ttaattaaag gagatgcacg ttttaaaaaa
    13921 gttattttag agggaaatta tagagagagt aacagggtac cttccatagt tgattttctt
    13981 tatgattttt ggtggctttt ctttcctgtt gccggatttt tagtttgggc cattcattcg
    14041 ttcatgggtt gattttaaaa tcaaaattta atgcacatca ggcaatatga aaaaggaaag
    14101 tatttttacg acaccttgaa atgtattgat aagaatagaa gagtttacaa aaggcaatat
    14161 gaaatatata ctaaaagtaa caagaatttc gtttgtaaac gcaccaaacc ccgaactatt
    14221 cgccgtagtt cggggttttt tggtgaattg gctttaatcg tctatattat tttttatcac
    14281 gtttatggag ctaataacca aataacgtaa cgagacaacc actgattgcc gttgtcatga
    14341 tgtgaacaag aatttcattc ataaatcgca cctcctctct acgccgaatt gacatctgag
    14401 agatagacga ccttcacatt ataacaaatc tctccttcca tgaaataaca tgaatattaa
    14461 taaatgttgt tatatattaa agataaataa atataagggt gggattgata atgtttggcg
    14521 atcaaagaca agaagctaca aaatatgtca ttaaagaagg ttatcaagat atttatttcc
    14581 tcaacaaaaa cggggaatgg tattatttcg aagtaagaag tgtctggcgt ggcaaacata
    14641 ttattagagt taaagatggt ttgttaggtt ggagaaaaga aatagtaact gaataaagat
    14701 acaaaatact tgccaatgca aaagaatgaa aacgcgtcaa atcaacgatg tataaaagat
    14761 gcataaaaga taatgaaagt aaaaagccat aaatgccgtc atataggcat ttatggcttt
    14821 ttgtttggtt aatataatcg atgattatca gaagttcaat tcacataaaa aagcacggct
    14881 aatttatgaa cttgtcgtac ctttttaatt aaaattagtt accaaataga cgactccaaa
    14941 accccttttt agcttccgtt tcttcactct tttcttctat atcactatca ttgtcatttg
    15001 gattagctga aacgtcttct ctttgtgctt cttcaccttg tgtactttcg tcgctttgac
    15061 ttccagatat atccttatat tgaatctctg tttctttagt ttcttcctga tctcggttaa
    15121 tatttacagg actagtagta tatgtttttt cttgtgcatc aacgttttgt ctagcgttag
    15181 tagatgtatc aaagggataa ttaaggtgtt tttctttttc taattgattt tctaattttt
    15241 gaatcttttt attactctct aatgccagaa cttgctgatt ctcaagcaat tttgatcttt
    15301 cttgcaactc ttttctgtaa aattcaattg ttgtttcatg acgactttct tgtttttcaa
    15361 tttgattatt taaagtatta atctgatttt taagtatttc tactatttga gcatcgcttt
    15421 tagattcaaa attaatatta tccgactctt ttttttgttt gtcttcagta gcactttcaa
    15481 aaccatattt ctttttattt tcatttactc tttgaatgat tttttctata tcggtatctt
    15541 ctttaataaa cgaagtgttt tcctgtttta ttgtctctat attcaatctc ttaatattat
    15601 taaaaatcgt ttgcttacta acccctaatt cttcactcaa cctttttaca cttttcatat
    15661 catcaaccct ttataaaatg tttataaacc cttagtaaaa tattataagc ttataacgat
    15721 taataataaa gtaatcgaca aataaaaata taaattcgcc aaccttttta tcaagggttt
    15781 gtaaagggtt tatggtgttt atcaaaggtt tataaaccta tattttccct tttttaagtt
    15841 tattcaaagt gctataataa ccttaatata acaaaaaccc caactactgg taatagtcgg
    15901 ggtttggtaa taaaacgttt agaaactgtt tatttatata attttcgata cttagattat
    15961 ataatgaata atatcttagt gcaagcacct agattattaa ataaacacaa aaaatgtaag
    16021 cgttttatta cctcttacca aactaaaatt cggaaagagg tttttattat gtcaattaaa
    16081 ctttacaaca taaatgagga atacagagaa aagttttatc aaataccgaa agtatttttt
    16141 acaaatccta aatatatcaa gttatccaat gatgcaaaaa tggcatgggg tattcttaga
    16201 gatcgtttag atttatcaat taaaaatggt tgggttgatt ctaaaacagg taatatttat
    16261 ttttattaca aaaatgaaaa cccacaaaat atattaaatt gtaaaaaaga taaagtaatt
    16321 aaaataaaga aagaacttaa ttgaagccga attactacta caagaaagac aaggtttaaa
    16381 taagacaaat aaactttatt tagttaaacc agaagtaaca gaagatgata tttataaaat
    16441 tcaaaagcaa gaaaacactg ttgagagcag caatggcaag gaagtcggaa aaaccgactt
    16501 caagaagtcg ataaaacaga atctaatgat actgaactta gctatactga atctaacaat
    16561 actgaaataa atgatatgaa tgacttgaat gatatagagt ccgaaaatga aattagtaat
    16621 cattcaagtc aatgcaaggt tatttaatgc aaacaatttt aactgaattt gaagaaacac
    16681 atgcacttta tatgcgccgt aaaaacatga aacaatataa tatctttaat caatcattca
    16741 aatgatttta taacaatcaa agatacatca aaatatttcg ttaaatcatc tgacttttta
    16801 actgatagcg atgaaaaaat caagaaattg tcagtgatct agaaaaagat ttgtatcgaa
    16861 aacgtatgtt aagttatggt ggattgctta aataaaaaca taaaatttta aacttagacg
    16921 atgctgaaga tggcaattta attaatacaa gtgatgaaga taaaatagca aatgaagaag
    16981 aaaaggcaca ttcgattacg gcaattttga aaagcaaaat tattatttaa ggcattagtg
    17041 ataactgatg tcttttttta ttactttttt gtaaaaaaag tgctgtctta tttttgtgac
    17101 aaatgctgta tgtagtgtca caaaagtgtg acacttgagc tttttatgac cccacacaaa
    17161 aacattttcg aagccttgaa atatctggct ttgccagatc ccccattcat tgatggggac
    17221 aaatttccct tatgctctta cggagatttt agagttaaat taaaatttct aagtttttga
    17281 taagaaaagc cctgcaggaa tttagaagaa cgtggggaag ttttaaagaa ttttatgcta
    17341 atttttaatt tgcatgtaaa tgggcagtgt ctaaaaaata gttattgttt ttgctcaaat
    17401 ttttgttttt gaaaatagca tatatttatt tggctcatat ttgcgtttta aaagcgtata
    17461 taagttttag ataaaactat atgaatcacc cctaaatctt taaaatgccc tcttaaaatt
    17521 caaaataagg gcataaaaaa taaaagcccc cccagataaa gtgaggtagc tttttctttc
    17581 gacgccgtat cgtcgatgta attcaaaaaa gttatgggct ataaatctac atcacttttt
    17641 caagaatgta gtagcaatat tcaacgcaaa ttaattttta taactgctcg gaatatctca
    17701 agccgtttct ttaattttga aataaaaaaa tcgacgaagg tcgattacgt ttttgcacat
    17761 gtcgatttat ccgacgtata agtgcgccct tacgggattt aactagatta taacgacgaa
    17821 ttttagacct gtaaagcaat aacaattagg tctaccaggt agataaagtg tacaaagtag
    17881 aaccgaaaaa gttatttatt ttgaagattt ttcgtagata taatttgcta ataaacttcc
    17941 taaaactgaa taaagaaaaa tagttaaact catgtaatca ctccataatt ctgaagtgtc
    18001 tccatgtcta cgcatagaca cgcatttatg ccgagaaaat ttattgtgcg ttgagaagaa
    18061 cccttaacta aacttgcaga cgaatgtcgg catagcgtga gctattaagc cgaccattcg
    18121 acaagttttg ggattgttaa gggttccgag gctcaacgtc aataaagcaa ttggaataaa
    18181 gcacctatga ttatttaaaa atataagtta taatacattc aaaaatattt ttgaatgagg
    18241 tgtattatga ttcaaacggt tgttgctgct gctgttcttt atattgctac agcagttgat
    18301 ttattagtaa ttttattaat attttttgct agagcaaaga ctagaaaaga atatagaaat
    18361 atttatgttg gtcaatattt agggtctatt attttaatat tagttagttt gtttttagct
    18421 tttgtattaa attatgttcc agaaaagtgg atattaggtt tattgggttt aataccaatt
    18481 tatcttggaa ttaaagtggc tatttatgat gattgtgaag gagaaaagag agctaaaaaa
    18541 gaattgaatg aaaaaggatt gtctaaatta gttggtacgg ttgcaattgt tacgatagca
    18601 agttgtggcg ccgataatat tggtttattt gttccttatt ttgtgacatt aagtgttact
    18661 aatttattac ttactctgtt tgtcttttta attttaattt tcttcttggt gtttactgca
    18721 caaaaattag ctaatatccc aggaattgga gaaattgttg agaaatttag tcgttggatt
    18781 atggctatca tttatatagc tttaggttta tttattatta ttgaaaatga cactattcaa
    18841 acaattttag gatttatatt ttaatttagg gtgtgatttt atatgagtta tgaaaatact
    18901 tgtgatgtga tctgtgtaca tgaggataaa gttaacaatg ctttaagttt tttagaagat
    18961 gataaatcta agaaattact taacatttta gaaaaaattt gtgatgagaa gaaattgaaa
    19021 atcatattat ctttgattaa agaagatgag ttgtgtgttt gtgatatttc tttgatattg
    19081 aaaatgagtg ttgcttcaac ttcacatcat ttaaggcttt tatataaaaa tgaggtactt
    19141 gatttttata aagatggaaa gatggcatat tattttatta aagacgatga aataagagag
    19201 tttttctcta aaaatcagga gggtttttga aacgagtgaa acgagtttct tcttgtcttg
    19261 atactataaa aaacaaagtt atataacata agacgactta tcggaagtta tctatcatcg
    19321 tatattcgga gatgatataa tatacaggtc gcctatctct caggcgtcaa ttcagacgca
    19381 gagaggaggt gcattacttt gctaatcatt ttcgttcaca tcatagcacc agtcatcagt
    19441 ggctgtgctg ttgcgtatta tacttattgg cttagtaaac gcaacaaata attaataggc
    19501 gactttataa gccagcatcg aaaaaatccc cacactattg cagtagtgtg gggattggtg
    19561 cattaattgt taatcatttt cgttatctag attataacac tggttagtag aggaatgcaa
    19621 aaagataata ttttaagtag tctttttgga tattatcata tgatatattt atgtaaattg
    19681 attttttatt aaaggagcat atatgagtaa tactaaaatt aaatatcaaa tttttatttc
    19741 atcaacttat ttagatttaa tagaagagcg tcaagcagta gtagaagcag ttttaaacag
    19801 taataatatt ccagcaggta tggaactttt taactcaagt agtaaaagcc aatgggaaat
    19861 aataacacaa tggatcaatg aatcagatgc agtgatatta ttgttaggtt ctagttatgg
    19921 aacaattgat agtgaagaaa atattagcta tacagaaatg gagtacaatt ttgctaaatc
    19981 tttaggtaaa cctatatatg tttttgagat gaataaagca tctaccgaat ccgcggaaaa
    20041 gtctaaaaaa ttagatgagt ttaagacaaa agttaaagaa aatagactaa ttagtccaaa
    20101 tattaatgat atttcggaat taaaaagtaa agtatctcag actttaatgc aaagtgtacc
    20161 tagtgaaatt aaagaaaata gtggatggat aagagtacag gattgtggta aaaatgtaaa
    20221 aaaattaaaa aaattggatg ctatacaaag agatttagat acatatgatt ttttgaaaga
    20281 agaactttat aaaatattca tgtatgtaaa aactttttat ttccagcaca caccatttga
    20341 tgatagttat attgaagata tagaaaacta cctgctaaat tatgaaaata atccacataa
    20401 atcattcatg aaaataaaag tttatgatta taaaaacttt ttaaaacatt taaaaaacat
    20461 attgatttta attaaacaag gaaaaaagcc attagctcaa gccggtcatt ttaaattaag
    20521 cttttacgaa gaggatttaa aattgttaca aaaaaattat aaggctacgc tagtcgatat
    20581 taaaggattg aataaacatt tttataagga atgtgatagg tgcttaaaag catataatat
    20641 ttttattgag ggt
//
