LOCUS       NZ_CP077910            20670 bp    DNA     circular CON 15-NOV-2023
DEFINITION  Staphylococcus aureus strain 322 plasmid unnamed1, complete
            sequence.
ACCESSION   NZ_CP077910
VERSION     NZ_CP077910.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN19550037
            Assembly: GCF_020388885.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 20670)
  AUTHORS   Wang,Z.
  TITLE     Comparative genomics reveals host-specific evolution and functional
            diversification of Staphylococcus aureus on human skin
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 20670)
  AUTHORS   Wang,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-JUN-2021) Comparative Microbiome Analysis Unit,
            Helmholtz Center Munich, Ingolstaedter Landstr. 1, Munich, Bavaria
            85764, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 01-JUL-2020
            Assembly Method                   :: HGAP v. 4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200X
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/15/2023 06:33:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,838
            CDSs (total)                      :: 2,756
            Genes (coding)                    :: 2,663
            CDSs (with protein)               :: 2,663
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 93
            CDSs (without protein)            :: 93
            Pseudo Genes (ambiguous residues) :: 0 of 93
            Pseudo Genes (frameshifted)       :: 63 of 93
            Pseudo Genes (incomplete)         :: 30 of 93
            Pseudo Genes (internal stop)      :: 18 of 93
            Pseudo Genes (multiple problems)  :: 16 of 93
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP077910.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..20670
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="322"
                     /isolation_source="Skin swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed1"
                     /geo_loc_name="Germany: Augsburg"
                     /lat_lon="48.22 N 10.54 E"
                     /collection_date="2019-02-06"
     gene            join(20625..20670,1..801)
                     /gene="blaZ"
                     /locus_tag="KU527_RS14040"
                     /old_locus_tag="KU527_14000"
                     /pseudo=""
     CDS             join(20625..20670,1..801)
                     /gene="blaZ"
                     /locus_tag="KU527_RS14040"
                     /old_locus_tag="KU527_14000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733274.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /name="blaZ"
     gene            1171..1704
                     /locus_tag="KU527_RS14045"
                     /old_locus_tag="KU527_14005"
     CDS             1171..1704
                     /locus_tag="KU527_RS14045"
                     /old_locus_tag="KU527_14005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823239.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001823239.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGKSIENRPV
                     LQEALNFLRMGDRFVVESIDCLGRNYDEVVGNPLLDKFMKDLIIQILAMVSEQERNESK
                     RRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRIIYHRVVEMLEEGQSISKIAKEVNIT
                     RQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            2119..2412
                     /locus_tag="KU527_RS14050"
                     /old_locus_tag="KU527_14010"
     CDS             2119..2412
                     /locus_tag="KU527_RS14050"
                     /old_locus_tag="KU527_14010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WP_000726502.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            2487..3620
                     /locus_tag="KU527_RS14055"
     CDS             2487..3620
                     /locus_tag="KU527_RS14055"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_225841127.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTAIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLILKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKKQLHS"
                     /name="hypothetical protein"
     gene            3691..4422
                     /locus_tag="KU527_RS14060"
     CDS             3691..4422
                     /locus_tag="KU527_RS14060"
                     /inference="COORDINATES: protein motif:HMM:NF018897.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="WP_151506432.1"
                     /translation="MIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQ
                     VLSKNVSVFSFDRTTNLKFGYLDSPIVMLLTLDDLTGDFYLAAVSQGGYLFKDLDTLKQ
                     LLKDNHLEEEISGITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFS
                     WNKKQLLLRKIHGYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQH
                     LLQIAYIKYLEKYFKDLMREI"
                     /name="DUF1430 domain-containing protein"
     gene            4426..4737
                     /locus_tag="KU527_RS14065"
                     /old_locus_tag="KU527_14020"
     CDS             4426..4737
                     /locus_tag="KU527_RS14065"
                     /old_locus_tag="KU527_14020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WP_000831610.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            4749..5375
                     /locus_tag="KU527_RS14070"
                     /old_locus_tag="KU527_14025"
     CDS             4749..5375
                     /locus_tag="KU527_RS14070"
                     /old_locus_tag="KU527_14025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000593103.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            5620..6250
                     /gene="mobV"
                     /locus_tag="KU527_RS14075"
                     /pseudo=""
     CDS             5620..6250
                     /gene="mobV"
                     /locus_tag="KU527_RS14075"
                     /inference="COORDINATES: protein motif:HMM:NF013258.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002446124.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            6344..6889
                     /locus_tag="KU527_RS14080"
                     /old_locus_tag="KU527_14040"
     CDS             6344..6889
                     /locus_tag="KU527_RS14080"
                     /old_locus_tag="KU527_14040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001805533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000273005.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTDFEKYTKQIKAAQMILD
                     DYECIKSGKSLKKAEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQEREIIFKEDREDGYTL"
                     /name="hypothetical protein"
     gene            7273..8133
                     /locus_tag="KU527_RS14085"
                     /old_locus_tag="KU527_14045"
     CDS             7273..8133
                     /locus_tag="KU527_RS14085"
                     /old_locus_tag="KU527_14045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000145511.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            8220..8561
                     /locus_tag="KU527_RS14090"
                     /old_locus_tag="KU527_14050"
     CDS             8220..8561
                     /locus_tag="KU527_RS14090"
                     /old_locus_tag="KU527_14050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000761341.1"
                     /translation="MKLAEAIKEQRELKGWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRVPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(8800..8871)
                     /locus_tag="KU527_RS14095"
                     /old_locus_tag="KU527_14055"
     CDS             complement(8800..8871)
                     /locus_tag="KU527_RS14095"
                     /old_locus_tag="KU527_14055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_106873653.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGY"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            9020..9205
                     /locus_tag="KU527_RS14100"
                     /old_locus_tag="KU527_14060"
     CDS             9020..9205
                     /locus_tag="KU527_RS14100"
                     /old_locus_tag="KU527_14060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466619.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSVWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            complement(9424..10167)
                     /locus_tag="KU527_RS14105"
                     /old_locus_tag="KU527_14065"
     CDS             complement(9424..10167)
                     /locus_tag="KU527_RS14105"
                     /old_locus_tag="KU527_14065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_225841119.1"
                     /translation="MKSVKRLSEELEVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESATEDKQKKESDNINFESKSDAQIVEILKNQINTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNAR
                     QNVDAQEKTYTTSPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAQREDVSANPND
                     NDSDIEEKSEETEAKKGFWSRLFGN"
                     /name="DUF536 domain-containing protein"
     gene            10578..11254
                     /locus_tag="KU527_RS14110"
                     /old_locus_tag="KU527_14070"
                     /pseudo=""
     CDS             10578..11254
                     /locus_tag="KU527_RS14110"
                     /old_locus_tag="KU527_14070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            <11265..11548
                     /locus_tag="KU527_RS14115"
                     /old_locus_tag="KU527_14075"
                     /pseudo=""
     CDS             <11265..11548
                     /locus_tag="KU527_RS14115"
                     /old_locus_tag="KU527_14075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            12757..13377
                     /gene="cadD"
                     /locus_tag="KU527_RS14120"
                     /old_locus_tag="KU527_14080"
                     /pseudo=""
     CDS             12757..13377
                     /gene="cadD"
                     /locus_tag="KU527_RS14120"
                     /old_locus_tag="KU527_14080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465246.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium resistance transporter CadD"
                     /name="cadD"
     gene            13396..13742
                     /locus_tag="KU527_RS14125"
                     /pseudo=""
     CDS             13396..13742
                     /locus_tag="KU527_RS14125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            13911..14003
                     /locus_tag="KU527_RS14130"
                     /old_locus_tag="KU527_14090"
     CDS             13911..14003
                     /locus_tag="KU527_RS14130"
                     /old_locus_tag="KU527_14090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            14215..15084
                     /locus_tag="KU527_RS14135"
                     /old_locus_tag="KU527_14095"
     CDS             14215..15084
                     /locus_tag="KU527_RS14135"
                     /old_locus_tag="KU527_14095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="WP_225841126.1"
                     /translation="MSNTKIKYQIFISSTYLDLIEERQAVVEAVLNSNNIPAGMELFNS
                     SSKSQWEIITQWINESDAVILLLGSSYGTIDSEENISYTEMEYNFAKSLGKPIYVFEMN
                     KASTESAEKSKKLDEFKTKVKENRLISPNINDISELKSKVSQTLMQSVPSEIKENSGWI
                     RVQDCGKNVKKLKKLDAIQRDLDTYDFLKEELYKIFMYVKTFYFQHTPFDDSYIEDIEN
                     YLLNYENNPHKSFMKIKVYDYKNFLKHLKNILILIKQGKKPLAQAGHFKLSFYEEDLKL
                     LQKIIRLR"
                     /name="DUF4062 domain-containing protein"
     gene            complement(15308..16123)
                     /locus_tag="KU527_RS14140"
                     /old_locus_tag="KU527_14100"
     CDS             complement(15308..16123)
                     /locus_tag="KU527_RS14140"
                     /old_locus_tag="KU527_14100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_225841123.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYNAPAEKQTKLRNDLYSITAIIDL
                     GQKLHVVNKYGHEHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKNETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            complement(16116..17559)
                     /locus_tag="KU527_RS14145"
                     /old_locus_tag="KU527_14105"
                     /pseudo=""
     CDS             complement(16116..17559)
                     /locus_tag="KU527_RS14145"
                     /old_locus_tag="KU527_14105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /name="DDE-type integrase/transposase/recombinase"
     gene            complement(17531..18124)
                     /locus_tag="KU527_RS14150"
                     /old_locus_tag="KU527_14110"
     CDS             complement(17531..18124)
                     /locus_tag="KU527_RS14150"
                     /old_locus_tag="KU527_14110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690638.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            complement(18390..18770)
                     /gene="blaI"
                     /locus_tag="KU527_RS14155"
                     /old_locus_tag="KU527_14115"
     ARG             complement(18394..18770)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            complement(18760..20518)
                     /gene="blaR1"
                     /locus_tag="KU527_RS14160"
                     /old_locus_tag="KU527_14120"
                     /pseudo=""
     CDS             complement(18760..20518)
                     /gene="blaR1"
                     /locus_tag="KU527_RS14160"
                     /old_locus_tag="KU527_14120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096376.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactam sensor/signal transducer BlaR1"
                     /name="blaR1"
     ARG             3..763
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.25"
                     /coverage="90.04"
     BGC             1..7412
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          11606..11753
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.333"
                     /coverage="100.0"
                     /evalue="2.96e-25"
     Typing          7274..8133
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(9425..10167)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          5621..5895
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="94.565"
                     /coverage="100.0"
                     /evalue="4.71e-46"
ORIGIN
        1 tgcatgtaat tcaaacagtt cacatgccaa agagttaaat gatttagaaa aaaaatataa
       61 tgctcatatt ggtgtttatg ctttagatac taaaagtggt aaggaagtaa aatttaattc
      121 agataagaga tttgcctatg cttcgacttc aaaagcgata aatagtgcta ttttgttaga
      181 acaagtacct tataataagt taaataaaaa agtacatatt aacaaagatg atatagttgc
      241 ttattctcct attttagaaa aatatgtagg aaaagacatc actttaaaag aacttattga
      301 ggcttcaatg acatatagtg ataatacagc aaacaataaa attataaaag aaatcggtgg
      361 aatcaaaaaa gttaaacaac gtctaaaaga actaggagat aaagtaacaa atccagttag
      421 atatgagata gaattaaatt actattcgcc aaagagcaaa aaagatactt caacgcctgc
      481 tgctttcggc aagactttaa ataaacttat cgcaaatgga aaattaagca aaaaaaataa
      541 aaatttctta cttgatttaa tgtttaataa taaaaacgga gacactttaa ttaaagatgg
      601 tgttccaaaa gactataagg ttgctgataa aagtggtcaa gcaataacat atgcttctag
      661 aaatgatgtt gcttttgttt atcctaaggg ccaatctgaa cctattgttt tagtcatttt
      721 acgaataaag acaataaaag tgataagcca aatgataagt tgataagtga aaccgccaag
      781 agtgtaatga aggaatttta atattctaaa tgcataataa atactgataa catcttatag
      841 ttttgtatta tattttctat tatcgttgac atgtataatt ttgatatcaa aacctgattt
      901 tccctttatt attttcgaga tttattttct taattctctt taacaaacta gaaatattgt
      961 atatacaaaa aatcataaat aatagatgaa tagtttaatt ataggtgttc atcaatcgaa
     1021 aaagcaacgt atcttattta aagtgcgttg cttttttctc atttataagg ttaaataatt
     1081 ctcatatatc aagcaaagtg acataattgt tgaatttata gtaactgaaa cgtatgatta
     1141 gggtgtatat taattatgag atggaaatca atgattgttg gctatgcgag agtatcatcg
     1201 aacgatcaaa atttagaaag acaacttgaa aatttaaaga cgttttgtgc tgaaaaaata
     1261 tttacagaaa aacagtctgg gaaatctatt gaaaatagac cagtacttca agaagcactt
     1321 aactttttga ggatgggaga tcggtttgta gtagaatcca ttgattgttt aggtcgtaat
     1381 tatgatgaag tggttggcaa tccattactg gataagttta tgaaagattt aattattcaa
     1441 atattagcaa tggtttcaga acaagagaga aatgaaagta aacgtcgaca agcgcaagga
     1501 attcaagttg cgaaggaaaa aggcgtatat aaagggcgcc ccttacttta ttcaccaaat
     1561 gctaaagatc cacagaaacg tattatttat catcgcgttg tagaaatgtt agaagaaggc
     1621 caatcaatta gtaaaattgc gaaagaagta aatataacaa ggcagacgat ttacagaatt
     1681 aaaaacgata atgatttgat ttaataaact ttgtttcaat gcaactgaga gcttctcaca
     1741 gcgtctcaaa acagatgatt ataatctatt atgagttttt aataataaga caagaaaaga
     1801 gagcgtaaat atgctctctc tttttctcat taacgaacgt ttataacgca atcatgatga
     1861 gagtattaat acagttaatt atttgaaata ctttagttta tataatgttg aattataggt
     1921 agtgaaattg tatttattat acattgtcat atcgttgttt aatgatagtt aatttaagga
     1981 taatagaatt aatattatat atagatgaac aaaacaagca acagagcaga aaaaaacact
     2041 tttagatcat ttttactcat tctctatttt atttattttt gctataataa ataaagaata
     2101 ttaaatggag gtgtttttat gaaaaagaaa tttgtttcta gttgtattgc tagtacaatc
     2161 ttattcggca ctttattagg tgtaacttat aaagctgaag ctgcaacagt acatgtagct
     2221 ggtggtgttt ggagccatgg tattggaaaa cattacgtat ggtcttatta tagtcacaat
     2281 aaaagaaatc atggttcaac agcagtaggg aaatattcat cttttagtgg tgttgctcga
     2341 cctggtgttc aatctaaggc atctgctcca aaggcttggg gtggaaacaa aacattttat
     2401 agtcttcact aattacatat attaattaag gagaatagac agaattaagt aaacttaatt
     2461 ctgtctattc tcttgaaaga ggcaatatga aaaaattcaa attattttta gattttagta
     2521 ctttattatt aatttcaggg ctattatttt tatttttctt caaagaaaat gaagaaatta
     2581 tacctgaaag ttccaatatt ttaacaatct ctaattggga taaatctaac agtaaatcaa
     2641 aagtgttaga tgtcattgaa tcaggcgcca aaaatcaaaa tatacaaata attaaatccg
     2701 ttaaagattt tgataataaa aaagaatttt ttgttttcaa ctcaaaacga aataattctg
     2761 actttatacg taataaaaca tcacttttaa ctccatcaga tttattaaac agagagataa
     2821 aaggaaagta ttatattatt ggtgaacatt tcaatgtaga agagcttacg agtgaattaa
     2881 aaaaagctgg tttaacatct gaagttgaat acataaatag aaacatatta ttttttgaat
     2941 tagtcataga taatgattta ttagtgcctt tcatattctt aggcgtatta tatcttttgt
     3001 acttcttata tgacagagga tataatttga aattttatgc tattcaaaag ctacatggct
     3061 tttcaactac acgcattatt tttcataata ttcatataaa aatcatttat tggctagtac
     3121 ttaccgctat tttctttatt gctaatatat taatcattca tatagccaat ttagaattgg
     3181 atttcttaat gtttattcgt agatttatcg tgttgctttt tgtttttgct tgtattacta
     3241 cattgctgtg gctgatttcg tatagtcttc ttttgaagtt aagtattcca ttaatcttaa
     3301 aagggaaaaa aggatataag ttttcaatat ttatgggtac cttcaccaaa tgtatcatgg
     3361 tgctaatact atctttttta ctggcacaaa atttaaatgc ttatacgaag ttaaagaata
     3421 tatatgactc tgaaaaaatc tggcaaaagt tagataatta ctatacatta gagatttctc
     3481 ctaatattag aaattcagaa gaaaaacaaa ttttagaaac taatatatac aatttaatta
     3541 agaaaagcga acaacttggt ggattgcttt taaagaataa taatatagcc aatcccgata
     3601 aaaaacaatt acattcctga aaatggcaat gtctttttta tcaataacaa ttttctgaat
     3661 ttctataaaa atataaatca tgattttaaa atgattgaca atcattcgga taaaataaac
     3721 gtgtttattc ctccaaggtt acaatatcaa aaatctgaaa ttcaaaaaaa tcaccaagga
     3781 tggattgact ttcaaaagca acaaaacaaa aaagtagatg tgcaagtact gtcaaaaaac
     3841 gtatctgttt tttcttttga tcgcacaact aatttgaaat ttgggtatct agattctcca
     3901 atagtaatgt tgttgacact tgacgattta acaggagatt tttatttagc tgctgtttct
     3961 caaggtggat atctatttaa agatttagat acacttaaac agttgcttaa agataatcac
     4021 ctagaagaag aaattagcgg tataactaat tacaaggatt ctgtgttaaa tgaattaaat
     4081 gaaacgaaaa caaaaatgat aataacaata gttactatta ttattaacgt tttcattctt
     4141 ttgatagcta ctgtatttga aacaattcaa tattttagct ggaataaaaa gcaactatta
     4201 ttaagaaaaa ttcatggtta ttcattattc agcagtaatg tacgttattt aacaatttct
     4261 atcttacttt ctattatgtt agcttacact acgcatattt tatttggttc aaagatatta
     4321 ctattcataa taatgtctat tgctattatt caacatttac ttcaaattgc ttatattaaa
     4381 tatcttgaaa aatactttaa agatttaatg agggagattt aaacaatgaa aagaacttta
     4441 attattgtaa caattgtact attaatcatc atacttagtc tgttattggt tagaaatgag
     4501 catttagatc gttttaaccc actgttaaaa gaaaaagtat cttatgccaa agttccaaaa
     4561 gatacccagg actatagaaa tataactgta tactctaaaa atggagaaaa aaagagttat
     4621 aaattggatt ttttaggtta tgatcctaca aaagaatatg tgaaagtaaa tcataaaggg
     4681 aaatatgtgc gttcgataga atacattaca aaagatattc ctagcttttt aaaatgaggt
     4741 gaccgatagt gataaaactt gaaaatgttt ttgtaaaaaa aggtaataaa aacattttag
     4801 acggatgtaa ctttaatttt gaaaaaggaa aatcatatgc tttagttgga gaaagtggcg
     4861 ctggaaaatc tactttactt aacataatcg ctgggttcga agatgtatca caaggaagca
     4921 tatatattga agataagtta ctaaaaaaga aagtcgattt ttatagatat acgttagggt
     4981 atttgtttca aaattttgct ttacttgaaa atcaaacaat cagtcaaaat ttagatttag
     5041 ccctaaagtt caaaaagaat aaaaaagata atatgaactt aaagaaagaa gtattaaaaa
     5101 aggtcggcct agatttagat atcaagagaa ttgttagttc tctaagcggt ggtgaacaac
     5161 aaagagtagc attggcaaga ttaatattaa aagatccgaa aatcatttta gctgatgaac
     5221 ctactgggtc actagatacg aaaaatggaa aaatagttat tgatttatta ttgaagctac
     5281 ttgatgaaaa taaaactatg attgtcgtaa cgcatgattt agagcttgcg aaacgatttg
     5341 atgtcatagt caatatttct gagcttagaa gttaagaaat attgataggt atagccatac
     5401 atagagaaaa aacaatatga aatatgatta gtcattactt ttgagttttt tgtcatcata
     5461 aaaaaggact ggattttcca gtcctttttt atgatgacaa aaaacaagcc tcgcagagca
     5521 cacgttttta atgacttatt tggtttttaa taagtctagt atgttaaaac ttttctgtgt
     5581 ttaggtgtta taatcatatg cagtggaagt tgatttatta tgtcttattc aattattcga
     5641 gttgttaaag tgaaatcaaa aacaaataca agaggtattc aaagacatat tcaaagagaa
     5701 aataaaaatt atgaaaatat agatattgat ttaagtaagt catatttaaa ctatgattta
     5761 gtcaatgata ctaagtttga ttttaataaa aaaattgatg agaaaatcga aaaaaattat
     5821 aaagggaaac gcaaaattag aacagatgcc attaaacata ttgatggatt aattacatca
     5881 gataatgtgt tttttaatca attatctgaa gaagagacaa aatagttttt taagcatgct
     5941 aaagcgttct tggaagaaga atacggtaaa gaaaatcttt tatatgcgac agtacatatg
     6001 gatgagataa caccacatat gcattatggc gtagttccta ttactaaaga tggacgttta
     6061 agtgcgaaag aagttgtagg taataaaaaa gcattaaccg aattccaaga tagattcaat
     6121 acgtatatta ataagcaagg ctatgattta aaacgaggaa tttctagaca acttacaaaa
     6181 gaaaaaacat gatcaagtta gccgttataa acaaaaaaca gaatatcata aacaaatgca
     6241 tatgcgctag aagcaaatag aggattattt aaagcaagaa aatgataaat tgatacaaaa
     6301 ctaccaaaaa tcattagata cgcttaaaaa gcttctgagt gtcatgtatg aaattaaaac
     6361 taaaaatgta ggtggatggt ttcataaaga gaagcaagaa acaggcaata ttgtaattac
     6421 taaaactgat tttgaaaaat acactaaaca aattaaagca gcacagatga tattagatga
     6481 ttatgaatgt attaaaagtg ggaagtcatt aaaaaaagca gagaaacaaa atgaaagttt
     6541 agttaatgaa ttgactagtg tccatatgga aaatgaaaag ctggttgaag aatttaatga
     6601 tttagcacaa cgttataatt atttgttgtc agagaatgaa aagaaagata aagaactaaa
     6661 ttatacgctt aagttattca atcaagtttt taaaatcatt aaaagtatga tgaaagaaga
     6721 gcgttatcat acactaataa atcatattga taatcattta gacaattcta aaatacgtga
     6781 agtaatgacg atagataaca atgatgaaca gttctttaag aagaaatatc aagcacaaga
     6841 acgagaaatc atttttaaag aagatagaga agatggttat acattataaa aatagatatt
     6901 taaatgcatt tgtttgaggt taattatttt ttaggatgaa aaataggtag cccccctcga
     6961 actttttaat atatttttat aaatcttttt aaaaaccttt ttaggggctt gttcagccct
     7021 agagcaacaa gggatttcaa tgcctaaagg agtgtttttg ccacataaaa ggagtgtttt
     7081 tgccacataa aaggagtgtt tttgccacat aaaaggagtg tttttgccac ataaaaggag
     7141 tgttttaaaa agttgtactc cttttatggt ttgacattga taataaagta gtttattgtg
     7201 aataaaagtt ttcaaatggg agtgtatatt caaacgatac tcctttaggt tcgtaataaa
     7261 gggggctgta tcatgacagg agagacagtt gtatataaaa atgaaatgaa tttagttcca
     7321 ttaaggcgat ttacagctac tgaaattaat ttattttttg cgatgtgtaa taaattaaaa
     7381 gagcaagata ctaatacatt acgtttgtct tttgatgaat taaaaaaatt aagtaattat
     7441 agtccagaaa cacgtaatat taatagattt gctaatgatt tagataatgt gtataaaaag
     7501 atgttgaatt taaccattag atatgaagat gatgatgtaa tagaaagatt cgttttattc
     7561 aatcattata gaatccataa gcgagaacaa tatctagaaa tatcaacttc ttcaaattta
     7621 aaacacatat tgaattcaat tactaataat tttacaaaat ttgaattaaa agaaatgact
     7681 aggcttaaat ctacatattc taaaaatatg tttagattac ttaaacaata caaacataca
     7741 ggctatttaa aaattcacat cgatgatttt aaaaatcgtt tagatatacc taaatcttat
     7801 cgtatgactg atattaacaa aaatgttttt aaacctatta ttattgaatt aggttctata
     7861 tttaataatc ttactatcaa taaaatcaaa gcgaaaaaag ggcgtaaaat tgaatggata
     7921 gagttcacat ttgacgctga gaaacgcatt cataacaaac gacaacctca aatgtccaag
     7981 atagataaat caagacaata tgtgaggcgt gaaaagacgc ctaaatggtt agaagaacgg
     8041 tcatatgaaa agcaacctca aaaagattac gacccacaat tagagaaaga acgagaggat
     8101 tttttaaaac aacttgaact gaattgggaa taacgcaact tttcgttgcg agttggttaa
     8161 ctaaaagtat cgtgactttt caattatttt aattatagtt tgagttaagg agtgatttta
     8221 tgaaattagc tgaagctata aaagaacaga gagaattaaa aggatggtct caagaggaat
     8281 tagccaatat attaaaggtt tccagacaaa gtgtttctaa atgggaaagt gccaaaaact
     8341 atccttcctt agatattttg attgctatga gcgatttatt cggaatctct ttagagcatt
     8401 taattaaagg agatgcacgt tttaaaaaag ttattttaga gggaaattat agagagagta
     8461 acagggtacc ttccatagtt gattttcttt atgatttttg gtggcttttc tttcctgttg
     8521 ccggattttt agtttgggcc attcattcgt tcatgggttg attttaaaat caaaatttaa
     8581 tgcacatcag gcaatatgaa aaaggaaagt atttttacga caccttgaaa tgtattgata
     8641 agaatagaag agtttacaaa aggcaatatg aaatatatac taaaagtaac aagaatttcg
     8701 tttgtaaacg caccaaaccc cgaactattc gccgtagttc ggggtttttt ggtgaattgg
     8761 ctttaatcgt ctatattatt ttttatcacg tttatggagc taataaccaa ataacgtaac
     8821 gagacaacca ctgattgccg ttgtcatgat gtgaacaaga atttcattca taaatcgcac
     8881 ctcctctcta cgccgaattg acatctgaga gatagacgac cttcacatta taacaaatct
     8941 ctccttccat gaaataacat gaatattaat aaatgttgtt atatattaaa gataaataaa
     9001 tataagggtg ggattgataa tgtttggcga tcaaagacaa gaagctacaa aatatgtcat
     9061 taaagaaggt tatcaagata tttatttcct caacaaaaac ggggaatggt attatttcga
     9121 agtaagaagt gtctggcgtg gcaaacatat tattagagtt aaagatggtt tgttaggttg
     9181 gagaaaagaa atagtaactg aataaagata caaaatactt gccaatgcaa aagaatgaaa
     9241 acgcgtcaaa tcaacgatgt ataaaagatg cataaaagat aatgaaagta aaaagccata
     9301 aatgccgtca tataggcatt tatggctttt tgtttggtta atataatcga tgattatcag
     9361 aagttcaatt cacataaaaa agcacggcta atttatgaac ttgtcgtacc tttttaatta
     9421 aaattagtta ccaaatagac gactccaaaa ccccttttta gcttccgttt cttcactctt
     9481 ttcttctata tcactatcat tgtcatttgg attagctgaa acgtcttctc tttgtgcttc
     9541 ttcaccttgt gtactttcgt cgctttgact tccagatata tccttatatt gaatctctgt
     9601 ttctttagtt tcttcctgat ctcggttaat atttacagga ctagtagtat atgttttttc
     9661 ttgtgcatca acgttttgtc tagcgttagt agatgtatca aagggataat taaggtgttt
     9721 ttctttttct aattgatttt ctaatttttg aatcttttta ttactctcta atgccagaac
     9781 ttgctgattc tcaagcaatt ttgatctttc ttgcaactct tttctgtaaa attcaattgt
     9841 tgtttcatga cgactttctt gtttttcaat ttgattattt aaagtattaa tctgattttt
     9901 aagtatttct actatttgag catcgctttt agattcaaaa ttaatattat ccgactcttt
     9961 tttttgtttg tcttcagtag cactttcaaa accatatttc tttttatttt catttactct
    10021 ttgaatgatt ttttctatat cggtatcttc tttaataaac gaagtgtttt cctgttttat
    10081 tgtctctata ttcaatctct taatattatt aaaaatcgtt tgcttactaa cctctaattc
    10141 ttcactcaac ctttttacac ttttcatatc atcaaccctt tataaaatgt ttataaaccc
    10201 ttagtaaaat attataagct tataacgatt aataataaag taatcgacaa ataaaaatat
    10261 aaattcgcca acctttttat caagggtttg taaagggttt atggtgttta tcaaaggttt
    10321 ataaacctat attttccctt ttttaagttt attcaaagtg ctataataac cttaatataa
    10381 caaaaacccc aactactggt aatagtcggg gtttggtaat aaaacgttta gaaactgttt
    10441 atttatataa ttttcgatac ttagattata taatgaataa tatcttagtg caagcaccta
    10501 gattattaaa taaacacaaa aaatgtaagc gttttattac ctcttaccaa actaaaattc
    10561 ggaaagaggt ttttattatg tcaattaaac tttacaacat aaatgaggaa tacagagaaa
    10621 agttttatca aataccgaaa gtatttttta caaatcctaa atatatcaag ttatccaatg
    10681 atgcaaaaat ggcatggggt attcttagag atcgtttaga tttatcaatt aaaaatggtt
    10741 gggttgattc taaaacaggt aatatttatt tttattacaa aaatgaaaac ccacaaaata
    10801 tattaaattg taaaaaagat aaagtaatta aaataaagaa agaacttaat tgaagccgaa
    10861 ttactactac aagaaagaca aggtttaaat aagacaaata aactttattt agttaaacca
    10921 gaagtaacag aagatgatat ttataaaatt caaaagcaag aaaacactgt tgagagcagc
    10981 aatggcaagg aagtcggaaa aaccgacttc aagaagtcga taaaacagaa tctaatgata
    11041 ctgaacttag ctatactgaa tctaacaata ctgaaataaa tgatatgaat gacttgaatg
    11101 atatagagtc cgaaaatgaa attagtaatc attcaagtca atgcaaggtt atttaatgca
    11161 aacaatttta actgaatttg aagaaacaca tgcactttat atgcgccgta aaaacatgaa
    11221 acaatataat atctttaatc aatcattcaa atgattttat aacaatcaaa gatacatcaa
    11281 aatatttcgt taaatcatct gactttttaa ctgatagcga tgaaaaaaat caagaaattg
    11341 tcagtgatct agaaaaagat ttgtatcgaa aacgtatgtt aagttatggt ggattgctta
    11401 aataaaaaca taaaatttta aacttagacg atgctgaaga tggcaattta attaatacaa
    11461 gtgatgaaga taaaatagca aatgaagaag aaaaggcaca ttcgattacg gcaattttga
    11521 aaagcaaaat tattatttaa ggcattagtg ataactgatg tcttttttta ttactttttt
    11581 gtaaaaaaag tgctgtctta tttttgtgac aaatgctgta tgtagtgtca caaaagtgtg
    11641 acacttgagc tttttatgac cccacacaaa aacattttcg aagccttgaa atatctggct
    11701 ttgccagatc ccccattcat tgatggggac aaatttccct tatgctctta cggagatttt
    11761 agagttaaat taaaatttct aagtttttga taagaaaagc cctgcaggaa tttagaagaa
    11821 cgtggggaag ttttaaagaa ttttatgcta atttttaatt tgcatgtaaa tgggcagtgt
    11881 ctaaaaaata gttattgttt ttgctcaaat ttttgttttt gaaaatagca tatatttatt
    11941 tggctcatat ttgcgtttta aaagcgtata taagttttag ataaaactat atgaatcacc
    12001 cctaaatctt taaaatgccc tcttaaaatt caaaataagg gcataaaaaa taaaagcccc
    12061 cccagataaa gtgaggtagc tttttctttc gacgccgtat cgtcgatgta attcaaaaaa
    12121 gttatgggct ataaatctac atcacttttt caagaatgta gtagcaatat tcaacgcaaa
    12181 ttaattttta taactgctcg gaatatctca agccgtttct ttaattttga aataaaaaaa
    12241 tcgacgaagg tcgattacgt ttttgcacat gtcgatttat ccgacgtata agtgcgccct
    12301 tacgggattt aactagatta taacgacgaa ttttagacct gtaaagcaat aacaattagg
    12361 tctaccaggt agataaagtg tacaaagtag aaccgaaaaa gttatttatt ttgaagattt
    12421 ttcgtagata taatttgcta ataaacttcc taaaactgaa taaagaaaaa tagttaaact
    12481 catgtaatca ctccataatt ctgaagtgtc tccatgtcta cgcatagaca cgcatttatg
    12541 ccgagaaaat ttattgtgcg ttgagaagaa cccttaacta aacttgcaga cgaatgtcgg
    12601 catagcgtga gctattaagc cgaccattcg acaagttttg ggattgttaa gggttccgag
    12661 gctcaacgtc aataaagcaa ttggaataaa gcacctatga ttatttaaaa atataagtta
    12721 taatacattc aaaaatattt ttgaatgagg tgtattatga ttcaaacggt tgttgctgct
    12781 gctgttcttt atattgctac agcagtttga tttattagta attttattaa tattttttgc
    12841 tagagcaaag actagaaaag aatatagaaa taattttatg ttggtcaata tttagggtct
    12901 attattttaa tattagttag tttgttttta gcttttgtat taaattatgt tccagaaaag
    12961 tggatattag gtttattggg tttaatacca atttagtctt gaattaaagt ggctatttat
    13021 gatgattgtg aaggagaaaa gagagctaaa aaagaattga atgaaaaagg attgtctaaa
    13081 ttagttggta cggttgcaat tgttacgata gcaagttgtg gcgccgataa tattggttta
    13141 tttgttcctt attttgtgac attaagtgtt actaatttat tacttactct gtttgtcttt
    13201 ttaattttaa ttttcttctt ggtgtttact gcacaaaaat tagctaatat cccaggaatt
    13261 ggagaaattg ttgagaaatt tagtcgttgg attatggcta tcatttatat agctttaggt
    13321 ttatttatta ttattgaaaa tgacactatt caaacaattt taggatttat attttaattt
    13381 agggtgtgat tttatatgag ttatgaaaat acttgtgatg tgatctgtgt acatgaggat
    13441 aaagttaaca atgctttaag tttttttaga agatgataaa tctaagaaat acttaacatt
    13501 ttagaaaaaa tttgtgatga gaagaaattg aaaatcatat tatctttgat taaagaagat
    13561 gagttgtgtg tttgtgatat ttctttgata ttgaaaatga gtgttgcttc aacttcacat
    13621 catttaaggc ttttatataa aaatgaggta cttgattttt ataaagatgg aaagatggca
    13681 tattatttat taaagacgat gaaataagag agtttttctc taaaaatcag gagggttttt
    13741 gaaacgagtg aaacgagttt cttcttgtct tgatactata aaaaacaaag ttatataaca
    13801 taagacgact tatcggaagt tatctatcat cgtatattcg gagatgatat aatatacagg
    13861 tcgcctatct ctcaggcgtc aattcagacg cagagaggag gtgcattact ttgctaatca
    13921 ttttcgttca catcatagca ccagtcatca gtggctgtgc tgttgcgtat tatacttatt
    13981 ggcttagtaa acgcaacaaa taattaatag gcgactttat aagccagcat cgaaaaaatc
    14041 cccacactat tgcagtagtg tggggattgg tgcattaatt gttaatcatt ttcgttatct
    14101 agattataac actggttagt agaggaatgc aaaaagataa tattttaagt agtctttttg
    14161 gatattatca tatgatatat ttatgtaaat tgatttttta ttaaaggagc atatatgagt
    14221 aatactaaaa ttaaatatca aatttttatt tcatcaactt atttagattt aatagaagag
    14281 cgtcaagcag tagtagaagc agttttaaac agtaataata ttccagcagg tatggaactt
    14341 tttaactcaa gtagtaaaag ccaatgggaa ataataacac aatggatcaa tgaatcagat
    14401 gcagtgatat tattgttagg ttctagttat ggaacaattg atagtgaaga aaatattagc
    14461 tatacagaaa tggagtacaa ttttgctaaa tctttaggta aacctatata tgtttttgag
    14521 atgaataaag catctaccga atccgcggaa aagtctaaaa aattagatga gtttaagaca
    14581 aaagttaaag aaaatagact aattagtcca aatattaatg atatttcgga attaaaaagt
    14641 aaagtatctc agactttaat gcaaagtgta cctagtgaaa ttaaagaaaa tagtggatgg
    14701 ataagagtac aggattgtgg taaaaatgta aaaaaattaa aaaaattgga tgctatacaa
    14761 agagatttag atacatatga ttttttgaaa gaagaacttt ataaaatatt catgtatgta
    14821 aaaacttttt atttccagca cacaccattt gatgatagtt atattgaaga tatagaaaac
    14881 tacctgctaa attatgaaaa taatccacat aaatcattca tgaaaataaa agtttatgat
    14941 tataaaaact ttttaaaaca tttaaaaaac atattgattt taattaaaca aggaaaaaag
    15001 ccattagctc aagccggtca ttttaaatta agcttttacg aagaggattt aaaattgtta
    15061 caaaaaatta taaggctacg ctagtcgata ttaaaggatt gaataaacat ttttataagg
    15121 aatgtgatag gtgcttaaaa gcatataata tttttattga gggtataaat aaacatttat
    15181 atgaatgata taagtacacc ctaatcatac atatataatt gttgtcactt tactcgatat
    15241 atgagaatga ctttacctaa taaatgagaa aagcaacgca ctatattaaa atgcgttgct
    15301 ttttctatta tcgaatacct ataactaaac tatctctagc tgtttctaca acttctgtac
    15361 ttattttatc taaaccattt atatccataa ttctgtctat ctgcgcaaat aaacgatgaa
    15421 tcagcctaaa attccctttt gtaattttaa taatcgtcgt tattgcctca taatcagtaa
    15481 agtcttcgag ttttaaatca aatcctaagt cttgccactt atattctaat atatgatgcg
    15541 tctcattttt acttagatta tcaaattcat gcgcaaaacc tatacgcgaa tatagttgag
    15601 gataacgaga tagttttttc tctatacccg gcataccaat aaatatcatt gctaaattat
    15661 gttcatcata aatagctctt aattgctcta aatgttgcac tttaaggcga tcaatctcat
    15721 ctactataat taaatcaata tatttaaaca tatcactata atgtttacta tgttcatgtc
    15781 catacttatt tacaacatgt aatttttgac ccaaatcaat gattgcagta atactatata
    15841 aatcattcct taatttagtt tgtttttctg ctggtgcatt ataaaatatt ttatccaccg
    15901 atagtatgtc atcggtcgtt ttactagcta aatcttccca acctctatgg ttaacttgtt
    15961 tttcaatagt atcccaattt gtgtaatacc tagacgataa agtttttccg acaccaggtt
    16021 gaccataaca tataccaata tactgatatt taatacaagc atcacaaaat tcagcaaagc
    16081 gtttatactc tttcgtttca atgaaatttt gatttttagt cattacgata tctctttaat
    16141 tttttgacgt ttttagtcgt ttcttgaggt gaataaccac aatttttttc ttccttaatt
    16201 aattccgtgg tacttggact agcaatattt tgttttaagt gttttcttct ctgactacga
    16261 gcgtgctgta tgtcttttat atctatggag taatcagcta tttctggaca tatagcagta
    16321 caaagaaatt catctctata aaacacacgt atttcagcca tatcatttgg gttataacga
    16381 atcagtacat attcacctac ataagcttct agattagtat tactgtatcg aaaaccttga
    16441 aaatgaatgc catctgaatg aacttttcta gatttaggta tttccaacaa taataaatca
    16501 agttgttcta agctacttgg catattaggg aaaaagtgat tactattcca atgactgata
    16561 ggcgtggtat gaatagtact atgttctttt tgattataat cttcaattaa aaagtaacgt
    16621 aatttttctt caaaattgtg aaaatttatt agattactag gagtatcatt attgtttata
    16681 tatccaggca gttgttctaa gaaagtttga ttaactgtct gaaagaatcg ttctattttt
    16741 ccacgaccac gaggaacacc aactttcgaa aacatcaagt taattttcaa atcaatagcg
    16801 acttgttcca tatgatgtga agtaaagtca cttccatgat ctgtgtagaa tttttcgggt
    16861 ataccacaca ctggccaatt ggtatcattt ttattccata ttgcttggtg tagtgttaat
    16921 gctgtgtttt gagcattggg gggcatcaaa acttaagaaa tagcctgcaa ttgcacgact
    16981 atagtcatcc ataataatag ttagccatgg tctattgata ttaccttttt ggtctaatat
    17041 aaagatatct agcaaagtat ggtctgcttg ccatatttca ttgggtctcg aggattctct
    17101 aatttgtatt aaatcgtact tattttgata gtatttttca ccctgatgag agaaatcaat
    17161 aacagactta ggcatcgctt taataacact ataaatttgt ttataacttg gtatatcaaa
    17221 attattttct ttacagtaat tagtgatttt cctatgaatt gtggctatac tatttctttt
    17281 attcataagc gcaaggcgtt caatttcatc aattatcttt ggttctattt tacgtgttcc
    17341 tttatcagct cttgtcgcat agattagtcc tttaagtcct tgttctttat atgacttatt
    17401 ccacctataa agggtgctta acgcaatccc tttactttta gaaatacttg ataaagattg
    17461 ttcgcctagg ataaaaggtt ttataatatt gtacttttga gtagcttttt tacgtttggc
    17521 ttcagaaaaa ttagttagat acttctcctt gtttttcatc ttccttgtcc tccaatttat
    17581 tgaggtaacg ataaattgtt gtacgtgaaa catgccactg ttctgcaatt gtcttaattg
    17641 gcgtgccatt atcataaagg gtcttaagta agtttaaatc tttttgattt aatttttctg
    17701 gtctgcctcc atatcggcct ctagcacgtg ctgcaattcg gccagctgaa gaacgctcta
    17761 aaattaaatt acgttcaaat tctgcaaatg ctgcgaataa atgaaataat aattgtccag
    17821 ttgaacttga tttatccatt gttatatttt cttctaaact atggaaactt acacctcgtt
    17881 cgttaagctc attaactaat gtgattaaat cctccatatt acgtcccaat ctatctaatc
    17941 tccaaacaac aatcgtatct cctgacctcg caaattcaat tgctttatct aaaccaggtc
    18001 ttttactttt tgaaccactc atatggtcat taaatatctt ttcacaacca tatgtattta
    18061 atcgatcctc ctgtaaattt aaattttgta atccagttga aactcttgca taacctattt
    18121 tcaaaataca aacctcctat atacatcttc agtgtaccat aacttaatta caaggtcttt
    18181 tatgaacata gattttttgt tgggtttttg aacacataat cctatgtaat tcttacttat
    18241 ttagacataa aagaagagtg tacagaaaat ggttattttc tgtacactct catctttaat
    18301 aatatatttt aaatgtcatt aacaaaacta atttaataag agtcaagcat agtttacata
    18361 tgtattatgt ttgaaacata cctctattat tactttttac taatatcatt taaaatatct
    18421 cgcaattctt caatttcttt gttatttaat tcttcatttt tcgcaaaatt caacactaaa
    18481 cttttcatat cccctccata cagtttatta agaaaggttt tagcagtttt cattttaata
    18541 tcgtcttctt taatatttga tgagtaaaaa taaatatttt ctgatttgta tcgttttata
    18601 atctcttttt tatatagtct tgtgattaat gttctaatcg ttttatcact aacttcttta
    18661 tatttttgaa tttcaactac aatttcatta gctgatactg attttttatc ccatattata
    18721 ttcataacat cccattcagc catagatatt tcaacttgct tattggccat ttaaaacacc
    18781 cattcctttt aatatttttt cacttattaa ttcagcattt ttcccagacg ggtttccatc
    18841 tgataaatgt gtagcaaaat aatacttatc atgatttgta attacgtaac ctacaaacca
    18901 cccattatta tacttcccgt ttactatacc tgtacctgtt ttcccataca gttcatactt
    18961 ttcatttttc ttaatcaata atgaagaaga taattgattc tttgcttttt tactaaaatg
    19021 gttattttgt tccatcatat ttttaaaaac tattacttgt tcaagattag atattttcaa
    19081 actatcttcc atccaatagc ttttataact tcccaaattt tcattaccat aatttaattg
    19141 cttgagttga gccgcagtat agttctttgg tatttgatta ctaatacgtt cgaagtacca
    19201 attaactgaa ttttgcattg ctgtatttaa atcttgttcc ttattccaag actcgaaaag
    19261 ataatgttta tgattccatg acatacgtga atttttatca cttataatat gacggtcaag
    19321 tccaaacagt gctaaataaa ttttgtaagt tgaatcagga gaatatcttt ttctactttc
    19381 tttttcatta taaatatagt atttgtcttt cttcatgctg tacataacga aagatccact
    19441 atttgaacca aaatttttac tttcatctaa aatttggtaa tcgctttgta agggcttttt
    19501 ataattataa tcagttaagg attgccccat taaaaactgg ctttgaatta tcatgataaa
    19561 aaaagtaaaa atacaaataa aaattagaat taattttgac tgctttttca gatcggcttc
    19621 ttttatatta attaatctat ttttgagtaa tgatttttta ccattaaatg aatggcttaa
    19681 tatatttttg ttgaaaaatg aggtttttaa tacggagtcc ataatagatt ccgcataagt
    19741 tttaaattca tttttgttaa tattattaag gacaaatcta tcggcttcta cttcattgtc
    19801 atgaattatc ttttcttttt acaatatgta ctaatggatt gtaactcata ataatagaga
    19861 agatattaaa gataattaaa tgtaaagtat ctctattttt agcatgagca tattcatgca
    19921 gtattatata ttttagtctt ttatcaatta cacttttaaa atatgaacta ggaatcaaaa
    19981 taatatattt cccataccaa aaagttattg gagattgaat agcctctgct tttcgaatca
    20041 caatattttt tttatattga tggttgaaaa gtatcgtatc tattttattt ttttcatttt
    20101 cgtttagata aagtgactgt ttctttaaat atttaagata taataaggct ttcaaaaatt
    20161 taaaacttaa aataataact aaaactatcc aaataactgt gcagatatta tcaattgaat
    20221 cccaattaaa cttatggata tctgttgcga actcttgaac aggtttggtg gtaattatgt
    20281 tatggttcaa gtcgtgtgac ttactttcaa ctgtgggcgc ttgattattc acattattaa
    20341 attttataaa agagaattta attgggataa aaggaattaa tccagcaagc acagttagat
    20401 accaaacttt ataatttaaa ctataattaa aatagcgttt taatatgtac ctaaaaaata
    20461 ctaacaatag aaatataaaa caaaagctta ctacactcat tattagtaat ttagccattt
    20521 tgacaccttc tttcaaatat ttataataaa caattgacat caatattaca attgtaatat
    20581 tattgttttg taaaaattac aactgtaata tcggagggtt tattttgaaa aagttaatat
    20641 ttttaattgt aatggcttta gttttttaag
//
