LOCUS       NZ_CP076865            16943 bp    DNA     linear   CON 10-JAN-2024
DEFINITION  Klebsiella pneumoniae strain V3 plasmid unnamed2.
ACCESSION   NZ_CP076865
VERSION     NZ_CP076865.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN19730657
            Assembly: GCF_019038575.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 16943)
  AUTHORS   Janssen,L., Almeida,F., Campos,T., Pappas,G., Martins,V. and
            Damasceno,T.
  TITLE     A novel multidrug resistant, non-Tn4401 genetic element
            (NTEKPC)-bearing, strain type of Klebsiella pneumoniae isolated from
            an urban lake with drinking and recreational water reuse
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 16943)
  AUTHORS   Janssen,L. and Almeida,F.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JUN-2021) Department of Cell Biology, University of
            Brasilia, Campus Universitario Darcy Ribeiro, Instituto de Ciencias
            Biologicas, Bloco K, 1 andar, Brasilia, DF 70910-900, Brazil
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye v. 2.7-b1585
            Assembly Name                     :: KpV3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 470.0x
            Sequencing Technology             :: Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/10/2024 02:23:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,343
            CDSs (total)                      :: 5,223
            Genes (coding)                    :: 5,007
            CDSs (with protein)               :: 5,007
            Genes (RNA)                       :: 120
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 216
            CDSs (without protein)            :: 216
            Pseudo Genes (ambiguous residues) :: 0 of 216
            Pseudo Genes (frameshifted)       :: 84 of 216
            Pseudo Genes (incomplete)         :: 57 of 216
            Pseudo Genes (internal stop)      :: 102 of 216
            Pseudo Genes (multiple problems)  :: 20 of 216
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP076865.1.
            Bacteria and source DNA available from Laboratorio de Analises
            Moleculares de Patogenos, Block I, Institute of Biological
            Sciences, University of Brasilia, Brasilia, Brazil.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..16943
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="V3"
                     /isolation_source="lake"
                     /db_xref="taxon:573"
                     /plasmid="unnamed2"
                     /geo_loc_name="Brazil: Paranoa Lake, Brasilia"
                     /lat_lon="15.740962 S 47.881235 W"
                     /collection_date="2019-02"
                     /collected_by="Luis Janssen"
     gene            129..2051
                     /locus_tag="KRP25_RS26190"
                     /old_locus_tag="KRP25_26190"
     CDS             129..2051
                     /locus_tag="KRP25_RS26190"
                     /old_locus_tag="KRP25_26190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015974470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protelomerase family protein"
                     /protein_id="WP_217049237.1"
                     /translation="MRKVKIGELINSLVNEVEAIDASDRPQGEKTKKIKAAAIKYKNAL
                     FNDKRKFRGKSLEKRISANTFNAYMSRARKRFDDKLHHNFEKNVIKLSEKYPLYNEELS
                     SWLSMPAASIRQNMSALQAKLKEIMPLAEDLSNIKIGAKNSDAKLAKLANKYPEWQFAI
                     SDLSSDDWKGKRDYLYKLFQQGSSLLEDLNNLKVNHEVLYHLQLSSAERTSIQQRWANI
                     LSEKKRNVVVIDYPRYMQAIYDIINKPISSFDLTTRRGMAPLAFALAALSGRRMIEIML
                     QGEFSVAGKYTVTFLGQAKKRSEDKGVSRKIYTLCDADLFVSLVNQLRSCPAAADFDEV
                     VKGYGENDTRSENGRINAILATAFNPWVKTFLGDDRRVYKDSRAIYARIAYEMFFRVDP
                     RWKNVDEDVFFMEILGHDDENTQLHYKQFKLANFSRTWRPHVGEENTRLAALQKLDSMM
                     PDFARGDAGVRIHETVKQLVEQDPSIKITNSTLRPFNFSTGLIPRYLEFAADALGQFVG
                     ENGQWQLKDEAPAIILPDEEVLEPMGDADLDDETQNDETLDDDEIEVDESEAVEPEEPD
                     EPEDDEEAEKAEKHPAKPNFKAPRDNGDGTFKVEFEFDGRHYAWSGAAGNRIEAMQFAR
                     HAYFE"
                     /name="protelomerase family protein"
     gene            complement(2106..2333)
                     /locus_tag="KRP25_RS26195"
                     /old_locus_tag="KRP25_26195"
     CDS             complement(2106..2333)
                     /locus_tag="KRP25_RS26195"
                     /old_locus_tag="KRP25_26195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015974472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_048993233.1"
                     /translation="MSQVQLNIQGLLESIEERLAQIEALVSSAHRTISSYEASLYMQEA
                     AELLQLARELVQEARNCSSSLSAQLAARES"
                     /name="hypothetical protein"
     gene            complement(2330..2494)
                     /locus_tag="KRP25_RS26200"
                     /old_locus_tag="KRP25_26200"
     CDS             complement(2330..2494)
                     /locus_tag="KRP25_RS26200"
                     /old_locus_tag="KRP25_26200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001542488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host cell division inhibitor Icd-like protein"
                     /protein_id="WP_048993234.1"
                     /translation="MFKFKFAAICRTDKKSHIHHLSTIASSEREARRQFASRFILVLSA
                     RIRVSEVIA"
                     /name="host cell division inhibitor Icd-like protein"
     gene            complement(2546..>2725)
                     /locus_tag="KRP25_RS26205"
                     /old_locus_tag="KRP25_26205"
                     /pseudo=""
     CDS             complement(2546..>2725)
                     /locus_tag="KRP25_RS26205"
                     /old_locus_tag="KRP25_26205"
                     /inference="COORDINATES: protein motif:HMM:NF022029.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ash family protein"
                     /name="ash family protein"
     gene            3027..4160
                     /locus_tag="KRP25_RS26210"
                     /old_locus_tag="KRP25_26210"
     CDS             3027..4160
                     /locus_tag="KRP25_RS26210"
                     /old_locus_tag="KRP25_26210"
                     /inference="COORDINATES: protein motif:HMM:NF013211.4"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140911 - pore-forming activity [Evidence
                     IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA];
                     GO:0050829 - defense response to Gram-negative bacterium
                     [Evidence IEA]; GO:0031640 - killing of cells of another
                     organism [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like pore-forming protein"
                     /protein_id="WP_217049238.1"
                     /translation="MPEETLTVVGGGNNSCNVSWGGGNGNNGGAGYSGKYGGTSYEGAT
                     SMLKLNDRVLIQLYLCNPLNPDYIGAPWGSDKDAESIIRANRDKPRKFKANIQNWKTSG
                     TGSLGSPVVGKSYSSGDVDTYSVSFGKEKYNVLYNRKKDSFTTAYVDGGANKPEHSMKD
                     QAIAVVKLYLLNESQASVIDTTSGIITDSGKTLSGKLGDKYNTLAREAADNIKNFQGKK
                     LRSFNDAMASINELANNPKMKLSQADKTVVSNALKQMDLSALADRFKGLEKAFTWGDRL
                     LKAEKIRDGVVTGVTTGDWQKLAFEVEAMYLSGVAGAVALGITTAMISTVAVALSLPSV
                     AVSALTVVAVIGISILTSYIDADKAKALNNAVLGLFK"
                     /name="colicin-like pore-forming protein"
     gene            complement(4840..5190)
                     /locus_tag="KRP25_RS26215"
                     /old_locus_tag="KRP25_26215"
     CDS             complement(4840..5190)
                     /locus_tag="KRP25_RS26215"
                     /old_locus_tag="KRP25_26215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015979712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_040108074.1"
                     /translation="MIYRKGWVPVLFRHELERKLKEQGFENWKEICNFLCGEGDDYAES
                     AKMPEQYDYQVVDNTKWMASRDATFWQRLNRLWFVPLYSLTIPFQWLIRGRVGFATTSK
                     TAALFSRITGLK"
                     /name="hypothetical protein"
     gene            complement(5187..5483)
                     /locus_tag="KRP25_RS26220"
                     /old_locus_tag="KRP25_26220"
     CDS             complement(5187..5483)
                     /locus_tag="KRP25_RS26220"
                     /old_locus_tag="KRP25_26220"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_217049240.1"
                     /translation="MAKDIDALLEQQADQMTSVLKSHAAHIESMLAQHRFQVAQLALHN
                     SPEPFVHEVFNHLRDRSVQVTINEAGLADAEDARYLLRILDRMELSALEGKPL"
                     /name="hypothetical protein"
     gene            complement(5476..9480)
                     /locus_tag="KRP25_RS26225"
                     /old_locus_tag="KRP25_26225"
     CDS             complement(5476..9480)
                     /locus_tag="KRP25_RS26225"
                     /old_locus_tag="KRP25_26225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001683860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid replication protein, CyRepA1 family"
                     /protein_id="WP_217049241.1"
                     /translation="MTLQEFYAARFGSDPYSLLEAARDELSELATMAGINWAACADNIQ
                     LNPRGGEERYSKYNGGAPEALEKSLKGRVEIYSRKEQHKSGISYPFVNFVQKGHDEGSW
                     SGFSFLFAEYRREQQRNHATVVAQPAEELARIERRAEARKRRAEQQRINELKNNQLEQE
                     RLLGWLAFHSAWEHAPAEDGSWPYAVKKGIRDVFSACDIRRVTSHDNAKWSRGPTTYMA
                     IPLAHLDGRKDGQIVGWQRIDQRGGKFQTSAITSGDFVGACFVIGNLNGAQNIAVVEGF
                     ATGASVWLATRKDPKKSFDAVVVAVVANNMIHVVEQLVNMYPAAKITCAPDNDRKSSAE
                     GKGNTGLRTGFDILAKFSGIKCVYPTFEDDPQLECSDFNDLHRLRGLRETCRQLFAKGN
                     RLSNSTDLLSLTLNKLKTAKRDNRRTFAKELLNAVDIGMLTCPVPNSPADLFNMFCIVL
                     RDMGLESVYRATVKDHIARRLNRKCRTARAPRSFSERITDPNKRPQHITYKRFETSVMT
                     DEILQYVQQLQGIVIVRAGMGSGKSTGLLRPLMHNADRGVSVAHRVSLIGGLWEMMTEQ
                     KGTKADILHYRDPGYQEMAPYANKLTICINSIVKGCWQPLMRQHDYFGFDEATQGLRAI
                     LSGRAMENPVAVFNTLIDALARTELHPIMVDADANDLLVDSAELAMKRREEMGLPAWLQ
                     IHVIELPVDVRNRETGEPIRVFYTEKDRIMTEVIKAVELGEKIMLATDSSTFAEDVTAT
                     LRQRYPEKKFLCVNQKSKPEPEVEEFTNKPKKMVKKYDGLIYSPSISSGVSIEQKHFDR
                     HFGMFCGEVVPSDAIQMLRRDRTAKEFIIGFDKVRARRETDPQKIERAFVQALLATAGM
                     NGELTDVVFDGDRISMGVANTDFTRMKIKAAAIEASARNDYASNMICIMHSDGYKVAPL
                     ASDELANCVGKELRKEAREIVWEQTLDLHLNIETPNESEREAILKKRALTLEEQAKLVR
                     WDIEHELKLPVNEDNLKFYFDGARDKVRRYETMLLDEITARRFDREESAINFTYAFRQA
                     GQWQYFTATAMTREQADEAFRAKHPGITEYKVKSTPAVEVGMRGFYGLKSTVLRQYFID
                     CGIDPETMTGEATQARLAYAEDKLMTAERRDLLNNVLRIGGFMTPKGKPKVPEALFKTI
                     CESLGLKTDKRRARDGDKRPTIRFVDQQSAAFMMEILENRKDDGLSLQLRKAEKATTEV
                     DHGLDLNIYMDHKTRSTNGQDLDAPHSVITEALAELPVPVPEAWAMTALSDDELATMTS
                     WSPASIAMTFASLYLTEFMDRLSSNELRRLREYITGTVTGGYDAQEAFYG"
                     /name="plasmid replication protein, CyRepA1 family"
     gene            complement(9731..10339)
                     /locus_tag="KRP25_RS26230"
                     /old_locus_tag="KRP25_26230"
     CDS             complement(9731..10339)
                     /locus_tag="KRP25_RS26230"
                     /old_locus_tag="KRP25_26230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015974480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_217049242.1"
                     /translation="MIDRMKTRGERLKARRLELKMTLKQVAQSVGISLPGVQNLERGDV
                     MPSLEIGLAPAKCLRKPVQWILFGTESDPDRVPVIGTTESGPDSDWQPGEPANTERFLP
                     FVSQRETVYALTVGNQVQHSYQPGDVVLVDSALTPVPGEDVLVCDKDGKISIQRLARFD
                     DERYYLDGVNSQRVIHEKSDLQFVHQIVGTIKSFMIEGR"
                     /name="helix-turn-helix domain-containing protein"
     gene            10420..10629
                     /locus_tag="KRP25_RS26235"
                     /old_locus_tag="KRP25_26235"
     CDS             10420..10629
                     /locus_tag="KRP25_RS26235"
                     /old_locus_tag="KRP25_26235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015974481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/CI family transcriptional regulator"
                     /protein_id="WP_032408972.1"
                     /translation="MKPEELIRHFGDVEKAAAGVGVTPGAVYQWLAAGEIPPLRQSDIE
                     VRTAYKLKSDFTVKRVSKDGSDGT"
                     /name="Cro/CI family transcriptional regulator"
     gene            10619..11356
                     /locus_tag="KRP25_RS26240"
                     /old_locus_tag="KRP25_26240"
     CDS             10619..11356
                     /locus_tag="KRP25_RS26240"
                     /old_locus_tag="KRP25_26240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015974482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage antitermination protein Q"
                     /protein_id="WP_217049244.1"
                     /translation="MELERIRACVVTALSDLHYLQRGILEVQLEQLRLANSGRFTDKPT
                     RVIQMGENNKYEISVAAEQVRYHVGKTFKQSSMLLTELDFQTASWRRAIEQLNREEIAR
                     LHYCYGCKPNFENDEVICQWLWLDFLVAHSKPDFKKMKEATKKKMRNLTYYAIQQVKAS
                     ILRGEDVDPLREDEHISLLLNITVDSWRKDYKKRWLLMKSRCLHLNSIALFNAAEKRSE
                     IINRHCTGSANVPVPADYAQEAR"
                     /name="bacteriophage antitermination protein Q"
     gene            11768..12376
                     /locus_tag="KRP25_RS26245"
                     /old_locus_tag="KRP25_26245"
     CDS             11768..12376
                     /locus_tag="KRP25_RS26245"
                     /old_locus_tag="KRP25_26245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015974483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="WP_217049246.1"
                     /translation="MLTYHQSIFKMIMANWLNSDHVIIDTETTGLMASDEIIEITIINM
                     RGEILLNTTVKPSRPIPPEVTKINNITNEMVADAPAWREVFPAALKIIRKHKWLAWNSS
                     FDARLMVQTCLQTGFFDDLKPHLITSIIMAIETRHIDAKAVYDQWYGEFDEKRKNFKRQ
                     SLATAAARHGISTAGAHRALADCLMILGVLKQVCQPEVA"
                     /name="3'-5' exonuclease"
     gene            12373..12507
                     /locus_tag="KRP25_RS26910"
     CDS             12373..12507
                     /locus_tag="KRP25_RS26910"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_023339399.1"
                     /translation="MNSELFNYSLKTLQVLNVVADLVLSVALFGFGYGLLNLLEWWLA"
                     /name="hypothetical protein"
     gene            12504..12980
                     /locus_tag="KRP25_RS26250"
                     /old_locus_tag="KRP25_26250"
     CDS             12504..12980
                     /locus_tag="KRP25_RS26250"
                     /old_locus_tag="KRP25_26250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019725492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_217049247.1"
                     /translation="MTDITRLINSIKRRTSSARELGYDVLFVALDDLDVSADSLETALR
                     ANAAQAAHIEQLQDTFNKLAAENVALKRVPETDSVAMLMALDSFRSESLPDVGLQKAFE
                     SLMYHRKTPTTVRIVAGIKADGVEEWVSSRGGRWNGTTEEALKFAKQLREGGKV"
                     /name="hypothetical protein"
     gene            12977..13222
                     /locus_tag="KRP25_RS26255"
                     /old_locus_tag="KRP25_26255"
     CDS             12977..13222
                     /locus_tag="KRP25_RS26255"
                     /old_locus_tag="KRP25_26255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010835575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_217049248.1"
                     /translation="MRLQMRTPDGSVIVESNPVSQFYPDYESGGELTTIETVSSDGEAS
                     FVKVKHSFHQVTHALATAWSVDEKEAMHTQREECRG"
                     /name="hypothetical protein"
     gene            13215..13541
                     /locus_tag="KRP25_RS26260"
                     /old_locus_tag="KRP25_26260"
     CDS             13215..13541
                     /locus_tag="KRP25_RS26260"
                     /old_locus_tag="KRP25_26260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015974489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_048292306.1"
                     /translation="MAKTPAERQRQRRERLKQSGTTRRDWVLEPEELRMLGEICIQRRP
                     GRTPYSENEVIGLLIRKNYKELQKSLANTCQRCGQALPVSECIFDGENSCLLTTARLKL
                     AIKA"
                     /name="hypothetical protein"
     gene            13562..13789
                     /locus_tag="KRP25_RS26265"
                     /old_locus_tag="KRP25_26265"
     CDS             13562..13789
                     /locus_tag="KRP25_RS26265"
                     /old_locus_tag="KRP25_26265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015974490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_217049250.1"
                     /translation="MDKSALLLEKLRQRTQSSSASGGDGFVFASMLVFDVGLNARTIRQ
                     MLDVAVRNGTLEKRERGIGRAHKYRTNLQI"
                     /name="hypothetical protein"
     gene            complement(14141..14428)
                     /locus_tag="KRP25_RS26270"
                     /old_locus_tag="KRP25_26270"
     CDS             complement(14141..14428)
                     /locus_tag="KRP25_RS26270"
                     /old_locus_tag="KRP25_26270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865085.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_217049252.1"
                     /translation="MKVKGIPFNQVKESLLNTPEAIRGYQEADKELALVEMLYEMREKA
                     GLSKSASAERMGITPSAISRLEGNPLGASMKTLSKYAQACGAEINIQAVY"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(14428..14736)
                     /locus_tag="KRP25_RS26275"
                     /old_locus_tag="KRP25_26275"
     CDS             complement(14428..14736)
                     /locus_tag="KRP25_RS26275"
                     /old_locus_tag="KRP25_26275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_023339392.1"
                     /translation="MFNVITHPAALEELQELPDELRGRMTRLIERLESEGKLKMPHSRV
                     IGAGLFELRVGDKNIARTLYAYAVGHEIYLLHAFVKKTQKTPAGAIEIARKRLKEMS"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            14907..15128
                     /locus_tag="KRP25_RS26280"
                     /old_locus_tag="KRP25_26280"
     CDS             14907..15128
                     /locus_tag="KRP25_RS26280"
                     /old_locus_tag="KRP25_26280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001543371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_023339391.1"
                     /translation="MNYQGNEKMRQDAAEISNELYELWQKVKRFQREYSFNSENITDRL
                     AGRLIGTMEPKLADLNSFMADVDYQFED"
                     /name="hypothetical protein"
     gene            15137..15367
                     /locus_tag="KRP25_RS26285"
                     /old_locus_tag="KRP25_26285"
     CDS             15137..15367
                     /locus_tag="KRP25_RS26285"
                     /old_locus_tag="KRP25_26285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015974495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_227509749.1"
                     /translation="MMNVKQIRENMTETALSVESVMRGHPRITLQELSTACSISLPAVE
                     FIIEQMLCMRVAQRGAFGRYSLTPEYQNGSF"
                     /name="hypothetical protein"
     gene            15685..16746
                     /locus_tag="KRP25_RS26290"
                     /old_locus_tag="KRP25_26290"
     CDS             15685..16746
                     /locus_tag="KRP25_RS26290"
                     /old_locus_tag="KRP25_26290"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017375494.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0008170 - N-methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="WP_217049253.1"
                     /translation="MKNTVKINSAELVHADSLEYIKTLPDNSLDAIITDPPYYRVKANA
                     SDNQWPSVTDYLAWLDEFFAEFWRVLKPAGSLYVFCGPKLSSDTELLLRDRFNVLNHIV
                     WAKPSGRWNGARKEGFRSYFPASEHIFFAEHYGAEGFAKGQAGYATKCRELKGQVFEPL
                     IAYFRDARQRLGISAAEINAATGTKMCSHWFSASQWQLPNERQYLALQALFNRKAAEQG
                     ISGLSEPHAALQEEYGTLTALYSELVMQYSELRQQYENLRRPFHVTKDVPHTNVWTYPP
                     VPYYPGKHPCEKPLQMMLDIISACTRPGDVIADFFMGSGATIKAALQLGRGAIGVELEE
                     ERFLQTVAEIEKQ"
                     /name="site-specific DNA-methyltransferase"
     Typing          complement(7982..9480)
                     /name="rep_cluster_1"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.4"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atctaaatat tgttatgtta tatttatgcg attatgttat gataataatg ccgagagatt
       61 gcgctttgat tgtgtgatgt ttctcagttt gtgttatgat gattaagggc gagaacagga
      121 ggtaggccat gcgtaaggtg aagattggtg agctaatcaa ttcgcttgtg aacgaggttg
      181 aggcaatcga cgcctcagat cgcccacaag gcgaaaaaac aaagaaaatt aaagccgcag
      241 ctataaaata taagaatgca ttatttaatg ataaaagaaa gtttcgcgga aaaagcttag
      301 aaaaaaggat ttcggctaat actttcaatg cctatatgag ccgggcaagg aaaagatttg
      361 atgataaatt acatcataat tttgaaaaaa acgtaataaa attatccgag aagtatccct
      421 tatacaatga ggaattatcc tcatggcttt ctatgcctgc ggcatcaatt cgacaaaata
      481 tgtcagctct gcaagccaag ctaaaagaaa taatgccatt agcagaagat ttatcaaata
      541 taaaaatcgg tgcgaaaaac agcgatgcaa aattagccaa acttgccaat aaatatccag
      601 aatggcaatt tgctattagt gatttaagca gtgatgattg gaagggtaag cgagattatc
      661 tttataaact cttccagcaa ggctcttcgc ttctggaaga tttaaacaat ctgaaagtaa
      721 accatgaggt cctctatcac ttgcagctta gctctgcaga gcgaacctcc atccagcagc
      781 gctgggccaa catactcagc gagaaaaagc gcaacgtggt tgtgattgac tatccgcgct
      841 atatgcaggc tatctacgat ataatcaata aacctatatc ttcgtttgat ttaaccaccc
      901 gtcgtggtat ggcccctcta gcgttcgcgc ttgcggcgct atctggtcga cgaatgattg
      961 aaatcatgct tcagggtgaa ttttccgtcg caggtaaata tacagtaaca ttcttaggac
     1021 aagctaaaaa acgctcagaa gataaaggtg tatcaagaaa aatatatact ctttgcgacg
     1081 ctgatttatt tgtcagtctg gttaaccaac ttcgctcctg ccctgctgct gcggattttg
     1141 atgaagtggt taaagggtat ggggaaaatg atacccgctc tgaaaatggt cgtattaacg
     1201 ctattctagc gacagcgttt aatccgtggg taaaaacttt cttaggcgat gaccgccgcg
     1261 tttataaaga tagccgcgct atttacgccc gcattgccta tgaaatgttt ttccgcgttg
     1321 atccacggtg gaagaatgtc gatgaggacg ttttcttcat ggagatcctc ggtcatgacg
     1381 atgaaaacac ccagctgcac tataagcagt ttaaattggc aaacttctcc agaacctggc
     1441 gcccacatgt tggcgaggaa aatacccggc tggcagcgct acaaaagctg gatagcatga
     1501 tgccagattt cgccaggggc gacgcagggg ttcgtattca tgagaccgtg aagcagctgg
     1561 tggagcagga cccatcaata aaaattacca acagcaccct gcgaccgttt aatttcagta
     1621 ccgggctgat acctcgctat ctggaatttg ctgcggatgc cttgggtcag ttcgtcggag
     1681 aaaatggcca atggcagctg aaggatgagg ctccagcgat aatcctgcct gatgaggaag
     1741 ttcttgaacc aatgggtgac gccgatctcg atgacgaaac ccaaaacgat gaaacgctgg
     1801 acgacgatga gatcgaggta gatgaaagtg aagccgtaga gccggaggaa ccggatgaac
     1861 cggaagacga cgaagaggct gagaaggcag agaagcatcc tgcgaagcca aactttaaag
     1921 cgccgaggga taatggtgat ggcaccttca aggtggagtt tgagttcgat ggccgccatt
     1981 atgcatggtc cggtgccgcc ggcaatcgga tagaggcaat gcaattcgcc cggcatgcct
     2041 acttcgaata acaaaaaggc cacaggttat cgcctgtggc ctttttaatt tccagctcta
     2101 caacatcagc tctccctggc ggccagctgc gctgacagag aggaggaaca gttacgggct
     2161 tcttgtacca gctcacgggc taactggagc aactccgccg cctcctgcat atacagcgag
     2221 gcctcatagc tagatatcgt ccggtgggct gaggaaacca acgcttctat ctgcgccagg
     2281 cgctcctcaa tcgactcaag caggccttgg atgtttagct gtacctgact cacgcgatca
     2341 cctcgctaac ccggatacgg gctgacagaa cgagaataaa acggctggcg aactgccggc
     2401 gggcttcacg ctcggatgag gcgatggtgg acagatgatg aatatgggat tttttatcgg
     2461 tacggcagat cgccgcgaac ttgaatttga acatggtatg cactcgtgtt tggttaaaca
     2521 gtgctaccac cagaggttcc aatctctata tggtggcagc ccagacgggg ttggaactac
     2581 cggtaccaaa cgaaaccggc cagtctttcg actgccccgc ctgagccgcc ataaattggg
     2641 catgcgcagg tattacacac aaaaaaacac gctggcgcgt gctgtgcgtc gtctggttat
     2701 tcggggttcc aatcccggct gcagattttg ctgcagcggg ctaactttac cgccaaaacg
     2761 caacgcacgt caataaatta catagagatt ttaccccgtg accagtcacg gcgacaggag
     2821 tttttacagc taacttgacc aactgatcac aacctgatca gtcggtttta ggaagggatg
     2881 gcaaaacacg gcgatgaccc atctttatgt aattatattt taacataatt taggattatt
     2941 gctggcttga cttaccggag ggttagggct acctttgagt ggctgtatat ttatacagct
     3001 aatttaaaac tcacaaggag attaacatgc ctgaagaaac attgactgtc gtaggtggtg
     3061 gtaataacag ctgtaatgtt agctggggtg gtggcaatgg taacaacggt ggtgctggct
     3121 attctggtaa atacggtggt actagctatg aaggtgcaac tagtatgttg aagttgaatg
     3181 accgtgtttt aattcagctt tatctttgca atccgctaaa cccagattat attggagcac
     3241 cttggggcag tgataaagat gctgaatcaa ttatcagagc taacagagat aaaccgagaa
     3301 aattcaaggc taatattcag aactggaaaa caagcggtac aggttcttta ggtagccctg
     3361 tggttgggaa atcttatagc tcaggtgatg tagatactta ttcggttagc ttcggaaaag
     3421 aaaaatacaa cgtcctgtat aaccgtaaaa aagactcttt tactacagct tatgtcgatg
     3481 gcggcgcaaa taaacctgag catagcatga aggatcaggc tattgccgtt gttaaacttt
     3541 accttctcaa cgaaagtcag gcatctgtaa tcgatactac atcgggaatt attactgact
     3601 ctggtaaaac tcttagcggg aaattaggtg ataaatacaa cactctggcg agagaagctg
     3661 ctgacaatat aaaaaacttc cagggtaaga aactccgcag ttttaatgat gctatggcat
     3721 ctattaatga actagctaac aatccaaaga tgaagttaag tcaggcggat aaaacagtcg
     3781 tttctaatgc cctcaaacaa atggatttgt cagcactagc tgaccgattc aaagggttag
     3841 agaaagcctt tacttggggt gatcgacttc ttaaagccga gaaaatcaga gacggtgttg
     3901 ttactggtgt taccacaggg gactggcaaa agctggcgtt tgaggttgaa gctatgtacc
     3961 tcagtggtgt tgctggcgcc gtagcgttag ggattactac tgccatgatt agcacagtcg
     4021 cagtcgcttt gtcacttcca tctgtagctg tctctgcgct tactgttgtg gccgtcattg
     4081 gcatctctat tctcacatct tatatcgatg ctgataaggc caaagcactg aataatgcag
     4141 tgcttggctt atttaaataa tacttatgtt tagtgtaaag cggaggttat ctccgctttt
     4201 gaaaaaaagg cagacctttt aaaagatata aataaatcaa aagcaaccaa ataaaaaaat
     4261 aattagtcag aaataaaaga atgtagtaaa ttaaaagaaa gcactcattg ccagcaataa
     4321 ttcttttaat gcgatacata ctatcagaca tattttccac acctacatat gttaaatagt
     4381 atgctcctgc cgttaaaagg agtacaccga gcagaagttt aagccatcgc ttcaaatcga
     4441 gtttgatggt ttttatatca aacttgttcc agcaaattat atacattaat atgacgaaaa
     4501 ttggtgcggt tttagtatat gcagaagcta tagtgctcac ggctaaatat tgttctgaaa
     4561 aatccctttg atatccattt gcaatatcaa aaaggtatga aatgatgtgt gagctttcat
     4621 tgctgaaatg aataaaaaat attattatta ttggggttat ccctaatagc aatgaaatta
     4681 atgaatattt gaacagcccc ttcccttcca tattatatcc caccattatc atgttaatga
     4741 tacgtaatca taaccgacaa atagaaaatg ataaaggttc tcaataccga caagctaacc
     4801 ggcccgagtc taatcgctcc gagccggaca tcgattattc tacttcaacc cggttatccg
     4861 gctgaataat gcagctgttt ttgacgtagt tgcaaacccg acacggccac ggataagcca
     4921 ctggaacggg atagtcaacg aatacagcgg cacgaaccac aggcggttaa gacgctgcca
     4981 gaacgtcgcg tcacggcttg ccatccattt ggtattgtcg accacctggt aatcatattg
     5041 ctctggcatt ttggctgatt cggcgtagtc atccccttca ccgcaaagaa aattacatat
     5101 ctctttccag ttttcgaaac cctgctcttt taacttacgc tcaagctcat gccgaaacaa
     5161 aaccggcacc catcccttgc ggtaaatcat aatggtttcc cctctaatgc tgacaattcc
     5221 atgcgatcaa gtattcgcag caggtaacgc gcatcctcag catcagcaag gccagcttca
     5281 ttgatggtga cttgtaccga gcgatcacgc agatggttga atacctcatg aacgaacggt
     5341 tccgggctgt tgtgcaatgc cagctgcgcg acctgaaagc gatgctgcgc cagcatgctt
     5401 tcaatatgcg ccgcatggct ttttaaaacg gaggtcatct gatccgcctg ctgttccaga
     5461 agtgcatcga tatctttagc catagaacgc ctcctgcgcg tcgtagccgc ccgtaaccgt
     5521 gccggtgatg tattcacgca gccggcgcag ttcgttgctg gagaggcggt ccatgaactc
     5581 tgtgaggtac agggacgcga aggtcatcgc tatgctggct ggcgaccagg aggtcattgt
     5641 ggccagctca tcatcagaca gcgcggtcat cgcccaggcc tccggcaccg gcaccggcag
     5701 ttcggccagc gcctcagtta ttactgaatg aggggcgtcc aaatcctgcc cgtttgtgga
     5761 tcgcgtttta tgatccatat atatattgag atctaaaccg tgatccactt cggtggtggc
     5821 tttctcggct ttacgcaact gcagagacag gccgtcgtct ttacggttct ccagaatttc
     5881 catcatgaac gccgccgact gctgatccac aaaccgtatg gtcgggcgct tgtctccgtc
     5941 cctggcgcgg cgcttgtcgg ttttcaggcc gagcgactcg cagatggttt taaacagcgc
     6001 ctcggggacc ttcggcttgc ctttgggcgt cataaagcca ccaatgcgca ggacgttgtt
     6061 taacaggtct cgccgttcgg cggtcatgag tttatcctcg gcgtatgcca ggcgcgcctg
     6121 ggtggcttct ccggtcatgg tttccgggtc gatgccgcag tcaatgaagt actggcgtag
     6181 caccgtagat ttgaggccgt agaagccgcg cataccgacc tcgaccgcgg gtgtcgattt
     6241 gactttgtac tcggtgatgc cagggtgttt cgcccggaat gcttcatcag cctgctcgcg
     6301 ggtcatcgcg gtggcggtaa agtattgcca ttggcccgcc tgcctgaaag cgtaggtgaa
     6361 gttgatcgcg gattcctcgc ggtcgaaacg ccgcgcggtg atctcatcga gcagcatggt
     6421 ttcataacgg cgaaccttat cgcgggcgcc atcgaagtag aatttcaggt tgtcctcgtt
     6481 gaccggcagt ttcagctcat gctcgatgtc ccagcggacc agcttcgcct gctcttccag
     6541 ggtcagggcg cgtttcttca gaatggcttc ccgttcagat tcgttcggcg tttcgatatt
     6601 caggtggaga tccagcgttt gttcccagac aatttcgcgg gcttccttgc gcagctcctt
     6661 gccgacgcag ttcgccagct cgtcggatgc cagtggggca accttgtagc cgtcgctgtg
     6721 cattatgcag atcatattgc tggcgtagtc attacgcgcg gaggcctcaa tcgctgctgc
     6781 cttgattttc atccgggtaa aatcggtgtt ggccaccccc atagaaatgc ggtcgccgtc
     6841 gaaaacaacg tcggttagtt cgccgttcat gccggcagtg gccagcaatg cttggacaaa
     6901 cgcacgctca attttttgcg gatcggtttc gcgtcgtgcg cgaaccttgt caaagccaat
     6961 gatgaactct ttggctgtgc ggtcgcggcg cagcatctgg atcgcatcgc tggggaccac
     7021 ttcgccgcag aacatgccga aatggcggtc gaaatgcttt tgctcgatgg agacgccgga
     7081 ggatatcgac gggctgtaaa tcaggccgtc gtacttcttc accatcttct tcggtttatt
     7141 ggtgaattct tcaacctcgg gttccggctt gctcttctgg tttacgcaga ggaatttttt
     7201 ctccgggtag cgctggcgca gcgtggcggt aacgtcttcg gcaaacgttg agctatcggt
     7261 cgccagcatg attttttcac cgagttccac cgctttaatc acctcggtca taatgcgatc
     7321 tttctcggtg tagaatacgc ggataggttc gcccgtttcg cggttgcgaa cgtcgaccgg
     7381 cagctcgatg acgtgaatct gtaaccatgc cggcaggccc atttcttcgc ggcgcttcat
     7441 cgccagttct gccgagtcga ccagcagatc gttagcatcg gcgtctacca tgatggggtg
     7501 caattcagtt ctggccagcg cgtcgatcag cgtattgaaa acggcgaccg ggttctccat
     7561 tgcgcggcca gaaagaatgg cgcgaagtcc ctgcgttgcc tcatcaaagc cgaaatagtc
     7621 atgctggcgc atcagcggct gccagcagcc tttgacgatg gagttgatgc aaatggtcag
     7681 cttattcgcg tatggcgcca tttcctgata gccggggtcc cggtaatgca gaatatcggc
     7741 cttggtccct ttctgctctg tcatcatttc ccacaggcca ccgatgaggc ttacgcggtg
     7801 cgcaacggaa acgccgcgat cagcgttatg catcaatggg cgcagcaggc ctgtcgactt
     7861 acctgatccc ataccggcgc gaacaataac gatgccctgc agctgctgca cgtattgcag
     7921 aatttcatcc gtcatcacgg atgtttcaaa gcgtttatac gtgatgtgct ggggacgctt
     7981 gttcgggtcg gtgatccgct cgctaaagga acggggagcc cgggcagtac ggcatttgcg
     8041 gttcaggcgg cgtgcgatgt ggtctttaac cgtggcgcga tagacacttt ccagtcccat
     8101 atcacgcagc acgatgcaga acatgttaaa cagatccgcc gggctattcg gtaccgggca
     8161 ggtcagcatg ccaatatcca ccgcgttcag cagttcttta gcaaacgtcc tgcggttgtc
     8221 acgtttagcc gttttcagct tgtttagcgt cagagacagc aaatcagtgc tgttactcag
     8281 gcggttccct ttggcgaata gctggcgaca ggtttcgcgg agtccacgta atctgtgcag
     8341 gtcgttgaag tcgctgcact ccagctgggg atcgtcttca aaggtgggat aaacgcattt
     8401 gatgccgcta aattttgcga gaatatcgaa gccggtacgt aagccggtgt tgcctttacc
     8461 ttcagccgat gatttgcggt cgttatccgg ggcgcaggta atttttgctg ccgggtacat
     8521 gttcaccagc tgctcaacaa catggatcat gttgtttgcg accacagcga ccacgacagc
     8581 atcaaagctt tttttcgggt ccttacgggt agccagccat acggacgcgc cggtggcgaa
     8641 accttccacc actgcaatat tttgcgcgcc gttcaggttg ccgataacaa agcacgcccc
     8701 gacgaaatca ccactggtga tcgcgctggt ctggaattta ccgccgcgct ggtcgatacg
     8761 ctgccagccg acaatttgtc cgtctttgcg tccgtccagg tgggccagcg gaatcgccat
     8821 gtatgtagtc ggtccacggc tccattttgc gttgtcgtga ctggtcacgc gacgaatatc
     8881 gcaagcgctg aatacgtcac gaatgccttt tttcactgcg taaggccacg acccgtcctc
     8941 agctggcgca tgttcccatg cactgtggaa cgccaaccat ccgagcaatc gttcctgctc
     9001 taactgattg tttttaagtt catttatccg ttgctgttcg gcgcggcgct tgcgggcttc
     9061 tgcccggcgt tcaatacgcg ccagttcttc agcaggttgt gcgaccacgg tcgcatgatt
     9121 tctttgttgt tcacggcggt attcggcgaa caggaaggag aagccgctcc aggaaccttc
     9181 gtcatgccct ttctggacaa agttgacgaa tgggtagctg atgccgcttt tgtgttgttc
     9241 cttgcgggag tagatttcca cacgcccttt gaggctcttt tccagagcct cgggggcgcc
     9301 accgttatat tttgaataac gttcttcccc gccgcgcggg ttcaactgaa tgttatcagc
     9361 acatgctgcc cagttaatgc cagccattgt ggccagctct gacagctcat cccgcgctgc
     9421 ttcaagcaat gaatacggat cgctaccgaa gcgagccgca tagaattctt gtaaggtcat
     9481 tttaagcctt tccatgcgaa tttatgattt ttcgggttga aaaaatccgc aggagcagcc
     9541 acaataaacg cacaaatctt cgtagggact gtgttgcgtt tatcgtggtg ctgctcctga
     9601 aaaaaggccc gagtttgccg actcgggttt tttttcgtct tttttcagct gctgcagtct
     9661 gattcaaccg cgatacatta tagctcgcat taaaccagat ttataggcag caataaaccc
     9721 tgttattctg tcatctaccc tctatcatga acgatttgat cgtaccgact atttggtgca
     9781 caaattgaag atcacttttc tcatggataa ctcgttgaga gttaacgcca tctaagtagt
     9841 agcgctcatc gtcgaagcgc gctaaccgct gtatcgagat tttcccgtct ttatcacaaa
     9901 ctaacacatc ctcacccgga actggcgtga gagctgagtc aaccaggacg acgtcacccg
     9961 gctgatagct gtgctgaacc tggttcccga cagtgagcgc ataaacggtt tcccgttggc
    10021 taacaaatgg caggaatcgt tctgtgttgg caggttctcc cggctgccag tcgctatccg
    10081 gaccactctc tgttgtgcca ataacaggaa cgcggtcagg atcagattca gtaccaaaaa
    10141 gtatccattg cacaggtttg cgcaggcatt tcgccggggc aagcccgatc tccagcgacg
    10201 gcataacgtc gccacgttct aagttttgga cgccaggaag agagataccg acactttgcg
    10261 cgacttgctt cagtgtcatc ttcaattcta aacggcgtgc tttcagtcgt tcgcctcgtg
    10321 ttttcatacg atcaatcata aacgatctct ttatagctgg ctataaaatt tatgaattat
    10381 acctagcttt aatttatggt tatggcatat aataatttta tgaagccaga agaacttatc
    10441 cgccactttg gcgacgtcga aaaagcagct gcaggcgtag gtgtaacacc tggcgcggtc
    10501 tatcaatggc ttgcggctgg ggagattcca ccgttacgcc agagcgatat tgaggtccgc
    10561 acggcataca aactgaagag cgacttcacc gttaagcggg ttagcaagga cggtagtgat
    10621 ggaacttgaa cgaatccgcg cttgtgtagt cacggccctt tcagatctgc attacctcca
    10681 gcgcggaatt ttagaagttc agcttgagca gttacgtctt gccaactccg gcaggtttac
    10741 tgataagcca acccgggtca ttcaaatggg cgagaataat aaatacgaga tctcggtcgc
    10801 ggctgagcag gttcgttacc atgttgggaa aacgtttaag caatcctcaa tgctgctgac
    10861 tgaacttgat tttcagacgg ctagttggcg cagagctatt gagcagttaa atcgtgagga
    10921 aattgctcgg ctgcattatt gctatggctg taagcccaat tttgaaaatg atgaagttat
    10981 atgccagtgg ctatggctgg attttcttgt cgctcattca aagcctgatt tcaaaaaaat
    11041 gaaagaggcg acaaagaaaa agatgcgcaa tttaacttat tacgccatcc agcaggttaa
    11101 ggcttcaata ttacgcggag aggatgtgga cccgctgcgt gaggatgagc atataagtct
    11161 tttgcttaat atcaccgtcg atagctggcg taaggattat aaaaaacgct ggctattaat
    11221 gaaatcacga tgcctgcatc tgaatagcat cgcgttattt aacgcagcgg agaagcgcag
    11281 tgaaatcatc aaccgccatt gtacaggaag tgccaacgtg cctgtgccag cagattatgc
    11341 acaggaagcc cggtaaaccc gaactgaggt atgccgcaaa ccgtaaagag tacattatct
    11401 ggtgcccaac ctgcgattac cggactcatc ctgatacgaa ccggcaatcg gttatcactg
    11461 aatggtacct gtcaaatcag ctcggtaata aacacatcga agatatgtgg ctgaaacgtt
    11521 atctggaaat aaaagagggt gcgaccgcgg tcgcataggg taatgatgcg aactccattt
    11581 aaacaaggcc ccatgtcata cgatgatgcg gtgcgaattt ctaacgttta tcgaaataaa
    11641 ggtcgagaga ctttaatcac gcgctcggat gatttagacg ggacgtatta cgtttttgtt
    11701 tatctccctg agtccagaaa agtcccaacg ccatccagaa cttttcaaca aaaaatatgg
    11761 gaataaaatg cttacctacc atcaatcaat ttttaaaatg attatggcaa attggctgaa
    11821 cagcgatcat gtcatcatcg atactgagac caccgggctt atggcttctg atgaaattat
    11881 cgagatcacg ataattaata tgcgtggtga gattctgtta aacaccacgg tgaagccgag
    11941 ccgccctatt ccgccagaag ttaccaaaat taataacatc accaacgaaa tggtcgctga
    12001 tgcgccagca tggcgcgagg ttttcccggc tgcgctgaaa attattcgta agcataaatg
    12061 gctggcatgg aactccagtt ttgatgcccg cctgatggtg cagacctgcc tgcagaccgg
    12121 attttttgat gacctaaagc ctcacctcat cacctccatc atcatggcca ttgagacgcg
    12181 ccacattgac gccaaagcgg tttatgacca gtggtatggg gagttcgacg agaagcgcaa
    12241 aaacttcaaa aggcagagcc tggctacagc agctgcgcgc cacggcattt caaccgctgg
    12301 cgcccatcgc gcgcttgccg attgcctgat gatcctcggc gtgctgaaac aggtttgcca
    12361 gccggaggtc gcatgaactc tgaactattc aactacagcc tgaaaacgct acaggtgctg
    12421 aacgttgtcg cagatttggt tttatcagtg gcgctgtttg gctttgggta cggccttctt
    12481 aacttgcttg agtggtggct tgcatgacag atatcacccg actgattaac agcattaagc
    12541 gccgcacgtc ctcagcaaga gagcttggct acgatgtcct gttcgtggca cttgatgatt
    12601 tggatgtctc ggctgattcg ctggagacgg cgctgcgcgc aaacgccgcc caggccgctc
    12661 acatcgagca gctgcaggac acgtttaaca aacttgcagc ggagaatgtg gcgctgaaaa
    12721 gagttccgga aacagacagc gtggcgatgc tgatggctct ggattcgttc cgcagcgagt
    12781 cattgccgga tgtcggtttg caaaaggcgt ttgaaagctt gatgtaccac cgaaagaccc
    12841 ctaccaccgt tcgtatcgta gccgggatta aggctgatgg agtggaagaa tgggtttcca
    12901 gcagaggtgg ccgctggaat ggcacgacag aagaggcgct taagttcgcc aagcagctgc
    12961 gcgaaggagg gaaagtatga gactgcaaat gcgcactccc gatggttctg tgattgtcga
    13021 gagcaacccg gtatctcagt tttaccccga ttacgaaagc ggtggtgagc taacaacaat
    13081 cgaaactgtt tcttctgacg gtgaagcctc ctttgtgaaa gttaagcact cgtttcatca
    13141 agtaacccat gctctggcta ctgcatggag cgtagatgaa aaagaagcga tgcacactca
    13201 acgggaggaa tgccgtggct aaaactcctg cagaacggca acggcagcgc cgtgaacgtt
    13261 taaagcagtc cggcaccacc agacgcgatt gggtacttga gccggaggaa ctgcgcatgc
    13321 tgggcgaaat ttgcatccag cgtcgcccgg gcagaacgcc gtattcagaa aatgaagtaa
    13381 tcggcctgtt gatccgaaag aattacaaag agcttcagaa gagcctggcg aacacatgcc
    13441 agcgatgtgg ccaggcgctg ccggtgtctg aatgcatctt cgacggcgaa aattcatgct
    13501 tactgacgac tgccagacta aagctggcca ttaaggcgtg actggtcacg gaggcttaaa
    13561 aatggataaa tcggcattgc ttttggagaa actccgtcaa cgaacgcaaa gtagctcggc
    13621 cagcggtggc gacggctttg tctttgcatc gatgctggtc tttgacgtgg gcttgaatgc
    13681 ccggactatt cggcaaatgt tggacgttgc agtaaggaac gggacccttg aaaaaaggga
    13741 aagaggcata ggccgcgcgc ataagtatcg gacaaatctg caaatttgat gagaaccttg
    13801 acaggaaatg acgttttagc atttgccaaa acgcctgtgt ttttatacag tatattaata
    13861 ttttgtaaga cgaataacgg gtaggctatg tgatggaaga tacggtcctc tcaaattgtg
    13921 aaaggctgga cgctgagctg agtgatatcg atgccgtatt agatatggta tcggtagcga
    13981 tggcatcccc ggaggccagt ttgcatgtgg ctcaaactat gcgcctcatt tgtatgtcac
    14041 gtcggatgct gcagcggtgc cgggatctca acaaggttga aggaagaagc cactagccag
    14101 ccgaattgaa aaaggtgagg tttccctcac ctttttacgt tcagtatacg gcctggatgt
    14161 taatttcagc gccgcacgct tgcgcgtatt tgctcagtgt cttcatgctg gcccccaggg
    14221 ggttcccctc gaggcgacta atagcagatg gcgtgatccc catccgttcc gccgaggcag
    14281 atttgcttaa cccagccttt tcacgcatct cgtacagcat ttcgaccagt gccagctctt
    14341 tatctgcttc ctggtaaccc cggattgcct ccggggtgtt gagcagactt tctttgacct
    14401 ggttaaatgg gatgcctttt actttcatta gctcatctcc ttcaggcgct ttctcgctat
    14461 ctctatggcc cctgccgggg ttttttgtgt cttcttaaca aacgcatgca gtaggtagat
    14521 ttcgtggccg actgcgtaag cgtataacgt tcttgctatg tttttgtctc caacccttaa
    14581 ctcaaaaagc ccggcgccaa ttacgcggct atgaggcatt tttagttttc cttcactttc
    14641 cagtctttca atcagtcggg tcatgcgacc tcgtaactcg tccggtagtt cctgtaactc
    14701 ttccagcgct gccgggtggg ttatcacgtt aaacatagta tatcctccct atgtgtttaa
    14761 atataccaat aaattaattt tcacacaata gagaaatttc actaaaaagt gaaaaataag
    14821 actggatgtc tcatgttgcc agagttacag ttcgtgtcgt tgagacggga aacaaacccg
    14881 gtaactagat gaatttggag gatattgtga actatcaagg caacgaaaaa atgagacagg
    14941 acgcggctga gatttctaac gagctgtatg aactctggca aaaagtgaag cgtttccagc
    15001 gtgagtacag cttcaacagc gagaacatta cagacagatt ggcgggccga ctgattggaa
    15061 caatggaacc caaactggcc gaccttaaca gctttatggc cgatgtcgat taccagtttg
    15121 aagattaaag ggggaaatga tgaacgtgaa acagatccgc gagaatatga ccgaaacggc
    15181 cttgagcgtt gagagtgtaa tgcggggaca cccccgcatc accctgcagg aattaagcac
    15241 tgcctgcagc attagcctgc cagcggtaga gtttattatc gagcagatgc tttgtatgag
    15301 ggtggcgcag cggggcgctt ttgggcggta ctcccttacc ccggaatacc aaaatggtag
    15361 cttttaaaaa ctgtgcgacc acggtcgcac agaaagaaaa ggataacttt tgaaaaactg
    15421 tgcgaccacg gtcgcataga aagaaaatga aaaaggttgg caaataaggc ttttttaggt
    15481 atcgtttttg tatgttggga attttatagc caacgccctc acaaccgccg ccaaggcggt
    15541 ttttttatgc cttggaaatg ggcgctacag catgtgtcac catgctgtag ctttcaaccc
    15601 atgccgcctg acagggtcaa aacaaggccc attgctgatt gcgcaacagc aaaaagagcc
    15661 taccaaaaaa ggccactaaa gaccatgaaa aacactgtga aaataaacag tgccgaactt
    15721 gtgcatgcag attcacttga gtacatcaaa accctgccgg acaacagctt agacgccatc
    15781 atcaccgacc caccgtatta ccgcgtaaag gcaaatgcct cggataacca atggcccagc
    15841 gtaacggatt atttggcttg gctggatgag tttttcgccg agttctggcg agtgcttaag
    15901 ccagcagggt cgttatatgt gttctgcggg ccgaaattat catcggacac cgagttgttg
    15961 ttacgtgacc gtttcaacgt gctgaaccat atcgtttggg ccaaacccag cgggcgctgg
    16021 aatggcgcgc gtaaagaagg tttccgatct tattttccgg ccagtgagca tattttcttc
    16081 gcagagcatt acggcgcgga aggctttgct aaaggccagg ctgggtatgc gacaaagtgc
    16141 cgggagttga aaggccaggt cttcgaaccg cttatcgctt atttccggga tgctcgccag
    16201 cgacttggta tttccgctgc cgaaatcaac gcggcaaccg gcacgaaaat gtgtagccac
    16261 tggtttagcg ccagccagtg gcaattgccc aatgaacggc agtacctggc gctgcaggcg
    16321 ctgtttaacc gtaaggccgc agagcaggga atatcgggat tgtcagagcc gcatgcggcg
    16381 ctacaggagg aatacggcac tttaacggcg ctatattccg aactggttat gcagtattcc
    16441 gaactgcgac agcagtacga gaatttgcgg cgccctttcc atgtgacaaa agatgttcca
    16501 cacaccaacg tgtggacgta tccaccggtt ccgtactatc cgggcaaaca cccatgcgaa
    16561 aaaccgctgc agatgatgct cgacatcatt tcggcttgta cgcgccctgg cgatgtgatc
    16621 gccgactttt ttatggggtc gggtgcaacg ataaaagccg cactgcagtt aggacgcgga
    16681 gccatcggcg tagagctgga agaggagcga tttttacaga cggtcgccga gatagaaaaa
    16741 caataatcaa cagcctcgcc taagtgcggg gctttttatt acccgccacg cgggtggcgg
    16801 agtcatgaac acagctatcg aatatggaaa tcctgatctc tggctggtct tgctcatgct
    16861 ggccgccggg gtggtatcaa gcgccctgct ttccgaaacc cctatcaacc cgcgccgcct
    16921 catcggagac gttctgagag gcg
//
