LOCUS       NZ_CP076309            26256 bp    DNA     circular CON 26-JUN-2023
DEFINITION  Escherichia coli strain Survcare253 plasmid pS253-CMY-42, complete
            sequence.
ACCESSION   NZ_CP076309
VERSION     NZ_CP076309.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN19349419
            Assembly: GCF_018771465.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 26256)
  AUTHORS   Nordmann,P., Yao,Y., Falgenhauer,L., Sadek,M., Imirzalioglu,C. and
            Chakraborty,T.
  TITLE     Recent emergence of aztreonam-avibactam resistance in NDM and OXA-48
            carbapenemase-producing Escherichia coli in Germany
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 26256)
  AUTHORS   Yao,Y., Falgenhauer,L., Chakraborty,T. and Imirzalioglu,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) Institute of Medical Microbiology,
            Justus-Liebig-University Giessen, Schubertstrasse 81, Giessen 35392,
            Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. v.0.4.7
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 560x
            Sequencing Technology :: Illumina NextSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 06/26/2023 02:24:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,013
            CDSs (total)                      :: 4,886
            Genes (coding)                    :: 4,617
            CDSs (with protein)               :: 4,617
            Genes (RNA)                       :: 127
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 95
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 269
            CDSs (without protein)            :: 269
            Pseudo Genes (ambiguous residues) :: 0 of 269
            Pseudo Genes (frameshifted)       :: 82 of 269
            Pseudo Genes (incomplete)         :: 176 of 269
            Pseudo Genes (internal stop)      :: 47 of 269
            Pseudo Genes (multiple problems)  :: 35 of 269
            Pseudo Genes (short protein)      :: 4 of 269
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP076309.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..26256
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="Survcare253"
                     /isolation_source="urine, catheter urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="pS253-CMY-42"
                     /geo_loc_name="Germany: Hesse"
                     /lat_lon="50.04 N 8.14 E"
                     /collection_date="2019"
                     /collected_by="IMM Giessen"
     gene            46..1077
                     /gene="repA"
                     /locus_tag="KNN07_RS24690"
                     /old_locus_tag="KNN07_24690"
     CDS             46..1077
                     /gene="repA"
                     /locus_tag="KNN07_RS24690"
                     /old_locus_tag="KNN07_24690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid replication initiator RepA"
                     /protein_id="WP_023518831.1"
                     /translation="MAGLKNTPYNAVHWSQLAPEEQIRFWEDYEAGRATTFLVEPERKR
                     TKRRRGEHSTKPKCENPSWYRPELYKALSGQLGHAYNRLVKKDPVTGEQSLRMHMSLHP
                     FYVQKRTYAGRKYAFRPEKQRLLDAIWPVLVSFSDAGTHTVGMSVSRLAREISPKDSKG
                     KVIPELEVTVSRLSRLLAEQVRFGVLGVSEETLWDRETRQRLPRYVWITPAGWQMLGVD
                     MVKLHEQQQKRLRESEIRQQLIREGVLREDEDISVHAARKRWYLQRSQDALKHRRAKAA
                     ASKRARRLKKLPADQQIHEMAEYLRKRLPPDEAYFCSDDHLKRLAIRELRQLELTLAAP
                     PPH"
                     /name="repA"
     gene            complement(2146..2655)
                     /locus_tag="KNN07_RS24695"
                     /old_locus_tag="KNN07_24695"
     CDS             complement(2146..2655)
                     /locus_tag="KNN07_RS24695"
                     /old_locus_tag="KNN07_24695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_012783913.1"
                     /translation="MSKSGAEKIQFILNNHEQAYRRLKPVYTFLELASWISVVLLIIYL
                     SGKNHVLTAAFLCFAWTAFWVLFLLHYFPKVFSILDRQSLLNLMEATKDSPDVKQELLN
                     RLFSGKRMTGRDEMDICRLLRKNEEEKIRQSELNIIRNFIDEQQLTNSDIPKKSTVPNE
                     DKKGIR"
                     /name="hypothetical protein"
     gene            complement(2711..3313)
                     /locus_tag="KNN07_RS24700"
                     /old_locus_tag="KNN07_24700"
     CDS             complement(2711..3313)
                     /locus_tag="KNN07_RS24700"
                     /old_locus_tag="KNN07_24700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001703912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ProQ/FINO family protein"
                     /protein_id="WP_001703912.1"
                     /translation="MEKNQEERKIPVIVVKKRRTFSLPSLSEKTDIIESAFTEQAAESA
                     PVGINSSAVETHIPEAPARKKKKKKRRFPRPSHWTREYTHECVEKIKILFPHLRAEGGG
                     FIPLKIGINNDISAFLAEHPETELTMDEWLCAVSCITSRRVYLQRTAVAGVPRYGLDGH
                     PKGQVSESEAQSAGRRLVTLEQKLLRMQAQQENISGQ"
                     /name="ProQ/FINO family protein"
     gene            3667..5013
                     /gene="yagA"
                     /locus_tag="KNN07_RS24705"
                     /old_locus_tag="KNN07_24705"
     CDS             3667..5013
                     /gene="yagA"
                     /locus_tag="KNN07_RS24705"
                     /old_locus_tag="KNN07_24705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001132032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YagA"
                     /protein_id="WP_039052405.1"
                     /translation="MPMILVKKNPRGKVIRELSSEEETAVKTVCGLKKPATMAQHNLAN
                     DLLREMREYDAWLQCDCIPGDSPAMNFAALKNNTGTLYLSSFNHEHAPECPMYRQLSGN
                     EEETSFGASRHPVSTRINYRNFLPPDDSNSVIRLQTRSAYHNGERSSVRKKRPRLGRLL
                     LSLIEDAGLNKLDSLANPRIRTNYRECLDAIRQVTLQQEYIRGRSLSEIIHFRPGMSER
                     SQERLMETLENSERHWPARRKHMFFQIFMAQHICRDAVEIHWANGNIQVFRPVRGISIN
                     GEAQGGIRPPYWVILAFCRSADGRIICSEGYAHALYQLTCPVPVDSKLERNTLTALLNV
                     ASWLKRKPGTPELSLERPLFDTEVYVNGEKKYVLPDFIVTAMAPDGKTARVVIETMGYE
                     DSDYCARKSRQHTGMKQIGVLHTDPPKWLDNDHPPFEKHMYGVFMHLRY"
                     /name="yagA"
     gene            complement(5536..5838)
                     /locus_tag="KNN07_RS24710"
                     /old_locus_tag="KNN07_24710"
     CDS             complement(5536..5838)
                     /locus_tag="KNN07_RS24710"
                     /old_locus_tag="KNN07_24710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001245884.1"
                     /translation="MRNRANTSPRDEAAFINGGTAGLDNTKKSSDKSSVVSKAKPVSIS
                     FFEENLKDIDALITAEMVSGKGRVNRSDVVRAAVEALKTLSKTEVSRLIAEVKQR"
                     /name="hypothetical protein"
     gene            complement(5835..6461)
                     /locus_tag="KNN07_RS24715"
                     /old_locus_tag="KNN07_24715"
     CDS             complement(5835..6461)
                     /locus_tag="KNN07_RS24715"
                     /old_locus_tag="KNN07_24715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010260829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family plasmid-partitioning AAA ATPase"
                     /protein_id="WP_000587689.1"
                     /translation="MIIVLGSQKGGVGKSTLAVSIAAYLMSLGNRVIIVDADDQKSVLT
                     WYNNRPEDLPHIPVTGATGNIKAMLKEHEKSYDFVIADCAGRDSAEMRSGLMAADVFIS
                     PLRPSQMDLDVVPHTCSVFTAAKDFNEDVRGYLVLNMTPTNMFVNEANEAAEVLKDYPE
                     MHLANSRVCDRKAHRDAWAESMTIFETQNDKAQQEIEALVKEVIL"
                     /name="ParA family plasmid-partitioning AAA ATPase"
     gene            complement(6649..7920)
                     /locus_tag="KNN07_RS24720"
                     /old_locus_tag="KNN07_24720"
     CDS             complement(6649..7920)
                     /locus_tag="KNN07_RS24720"
                     /old_locus_tag="KNN07_24720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001744069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="WP_001703910.1"
                     /translation="MFALADINSFYASCEKVFRPDLRNEPVIVLSNNDGCVIARSPEAK
                     ALGIKMGQPWFQVRQMRLEKKIHVFSSNYALYHSMSQRVMAVLESLSPAVEPYSIDEMF
                     IDLRGINHCISPDFFGHQLREQVKSWTGLTMGVGIAPTKTLAKSAQWATKQWPQFSGVV
                     ALTAENRNRTLKLLGLQPVGEVWGVGRRLTEKLNALGINTALQLAQANTAFIRKNFSVI
                     LERTVRELNGESCISLEEAPPAKQQIVCSRSFGERITDKDAMHQAVVQYAERAAEKLRG
                     ERQYCRQVTTFVRTSPFAVKEPCYSNAAVEKLPLPTQDSRDIIAAACRALNHVWREGYR
                     YMKAGVMLADFTPSGIAQPGLFDEIQPRKNSEKLMKTLDELNQSGKGTVWFAGRGTAPE
                     WQMKREMLSPAYTTRWTDLPVAQL"
                     /name="Y-family DNA polymerase"
     gene            complement(7920..8339)
                     /gene="umuD"
                     /locus_tag="KNN07_RS24725"
                     /old_locus_tag="KNN07_24725"
     CDS             complement(7920..8339)
                     /gene="umuD"
                     /locus_tag="KNN07_RS24725"
                     /old_locus_tag="KNN07_24725"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457137.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translesion error-prone DNA polymerase V
                     autoproteolytic subunit"
                     /protein_id="WP_057109540.1"
                     /translation="MVSCFPHRSRLQQTQFADRCQAGFPSPATDYAEQELDLNSYCISR
                     PAATFFLRASGESMNQAGVQNGDLLVVDRAEKPQHGDIVIAEIDGEFTVKRLLLRPRPA
                     LEPVSDSPEFRTLYPENICIFGVVTHVIHRTRELR"
                     /name="umuD"
     gene            8697..10598
                     /gene="ltrA"
                     /locus_tag="KNN07_RS24730"
                     /old_locus_tag="KNN07_24730"
     CDS             8697..10598
                     /gene="ltrA"
                     /locus_tag="KNN07_RS24730"
                     /old_locus_tag="KNN07_24730"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936286.1"
                     /GO_function="GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="WP_000936285.1"
                     /translation="MLPDELEKRLDGIEDASKKGYPVRNLYKIACEPGLWLQAYVNIRA
                     NAGALTQGVSTDTIDGFSIERAEKLAKTLRSREYVAKPVRRVQIPKKDGKTRPLGIPGG
                     DDKLAQEVARIILERVYEPVFSEHSHGFRPKRSCETALRSIRPVWNGVKWIVDVDIKGF
                     FDNIPHKLLLNTLAEKIKDKNFLKLIEQWLKAGYVDNWKYHRSYSGTPQGGIISPLLAN
                     IYLDKLDRFVEQNLIPAYTSGTKRRANPDMNRLAHKIHKLRKKVDGMATDSESEKEAIK
                     KEIERLLEEKRSIPSQVMNDPNFRRMYYVRYADDFVIGVIGSKKDAEHISRQVRNFITT
                     SLGLEVNEAKTRIRHISEGVNFLGYEIRQADAKKLLKQKMQGRHALRRSTTGIVQLFVP
                     DNIAAKFCHQKKYGCYENVKAVHRSSLQNLSEAEIVLTFNAEMRGLANYYSLALDMKYK
                     LSKLYFIWQISLFKTLANKRRSSVNKVAKSLRQNNGDLAITVQAKNGSRKIEVFKLKHV
                     NRNRTTIVDTEPRTAHITTRTTEIMRRLGARICEYCAKTGRCEVHHVRKLKDLKKGRKA
                     GYKPSLWQLMMIARRRKTMILCASCHDKLHSGKLPDLRQEKGRILLQPPVSSGDSAK"
                     /name="ltrA"
     gene            <10781..>11674
                     /locus_tag="KNN07_RS24735"
                     /old_locus_tag="KNN07_24735"
                     /pseudo=""
     CDS             <10781..>11674
                     /locus_tag="KNN07_RS24735"
                     /old_locus_tag="KNN07_24735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052657.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            <11669..12022
                     /locus_tag="KNN07_RS24740"
                     /old_locus_tag="KNN07_24740"
                     /pseudo=""
     CDS             <11669..12022
                     /locus_tag="KNN07_RS24740"
                     /old_locus_tag="KNN07_24740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001584594.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid SOS inhibition protein A"
                     /name="plasmid SOS inhibition protein A"
     gene            12019..12615
                     /locus_tag="KNN07_RS24745"
                     /old_locus_tag="KNN07_24745"
     CDS             12019..12615
                     /locus_tag="KNN07_RS24745"
                     /old_locus_tag="KNN07_24745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000978013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000977995.1"
                     /translation="MMKSDEKYQVPAWMRPLLPLLCNTGGNDPEELLNDTETTASANVV
                     RYVLIVAVRSQVDLLQLLYRKGLLRTEIPGGFSPEEAQALLDNLVRSHISKALSGERMA
                     ARDRNADLAWIGQQLVDAAWFVRATLEAHGMSVGNESPPAPPETMPDIQTRELVMLIKR
                     LASSLKAVKPDSCVVREAQDWLRDRKLVDITDILR"
                     /name="hypothetical protein"
     gene            complement(<13098..13457)
                     /locus_tag="KNN07_RS24750"
                     /old_locus_tag="KNN07_24750"
                     /pseudo=""
     CDS             complement(<13098..13457)
                     /locus_tag="KNN07_RS24750"
                     /old_locus_tag="KNN07_24750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151583.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DsbC family protein"
                     /name="DsbC family protein"
     gene            complement(13476..14684)
                     /gene="trbA"
                     /locus_tag="KNN07_RS24755"
                     /old_locus_tag="KNN07_24755"
     CDS             complement(13476..14684)
                     /gene="trbA"
                     /locus_tag="KNN07_RS24755"
                     /old_locus_tag="KNN07_24755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000121273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type conjugal transfer protein TrbA"
                     /protein_id="WP_011264049.1"
                     /translation="MSYNRQPVAEDPMQIWGAVGVLLILLLFVIWLFLPEVVYASCLIL
                     HTLWGLVDWGPFHNYAAPRYNLLAMTGNNAANISYSQWVNVMEQTIGILWMYLLPVTLW
                     CLWEWYQHPGQSRFTRRPVDITRLPHIFASLSPAIAPVLEDGDPEKLFHGGKRPERRVA
                     LTPEAFVEQHTLITNMQLDVAAARRCFMAQLGKPLTSWKDMAPHEKALFAIFGLQYFLD
                     DRKAALKLMDTLNLSCRIKSKRDSGKFCTPVYSLAKSAFKRVIKSDGAQQWLKQHRYVR
                     SGLVWLYAHDLRLTPPNWIWLKGVDRTLFYALHRANTTKGFIEGAGVVAVARAEAEAMR
                     FGLPCPEPCVDEAVEGLRRDMLSLGLIWDEPQPDRDRKRRILTNWSLTDDILPRTPATD
                     NEF"
                     /name="trbA"
     gene            complement(14991..15773)
                     /gene="finQ"
                     /locus_tag="KNN07_RS24760"
                     /old_locus_tag="KNN07_24760"
     CDS             complement(14991..15773)
                     /gene="finQ"
                     /locus_tag="KNN07_RS24760"
                     /old_locus_tag="KNN07_24760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_023063753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein FinQ"
                     /protein_id="WP_023063753.1"
                     /translation="MMKGFLKPESRDNIPAQILKELPSWSIYVSAENLHTILPTSYPIH
                     GFFFYPFLDNNGNIIRLFIIDDLKQSQGTTGLKEKNVDVVNNIIRIKDSREGLLDSRKM
                     ECIDGEVVVTVNEKLKDFRDREFNLLNAQISMVLYICSQINDIKEKNQFKRSEKHKKHV
                     HTHHELPAQNIREWDVGIRMGQAIRQYRQAEPTGKERTTIGSKRPHIRRGHWHTYWTGS
                     KKPELAHERKPRLIWLPPVPVNLEDVNKLPVVITPIDK"
                     /name="finQ"
     gene            15969..16286
                     /gene="sugE"
                     /locus_tag="KNN07_RS24765"
                     /old_locus_tag="KNN07_24765"
     CDS             15969..16286
                     /gene="sugE"
                     /locus_tag="KNN07_RS24765"
                     /old_locus_tag="KNN07_24765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463202.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="WP_000118520.1"
                     /translation="MSWIVLLIAGLLEVVWAIGLKYTHGFTRLTPSIITIAAMIVSIAM
                     LSWAMRTLPVGTAYAVWTGIGAVGAAITGILLLGESASPARLLSLGLIVAGIIGLKLST
                     H"
                     /name="sugE"
     gene            complement(16283..16816)
                     /locus_tag="KNN07_RS24770"
                     /old_locus_tag="KNN07_24770"
     CDS             complement(16283..16816)
                     /locus_tag="KNN07_RS24770"
                     /old_locus_tag="KNN07_24770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin family protein"
                     /protein_id="WP_001221666.1"
                     /translation="MRILPVVAAVTAAFLVVACSSPTPPKGVTVVNNFDAKRYLGTWYE
                     IARFDHRFERGLDKVTATYSLRDDGGINVINKGYNPDREMWQKTEGKAYFTGDPSRAAL
                     KVSFFGPFYGGYNVIALDREYRHALVCGPDRDYLWILSRTPTISDEMKQQMLAIATREG
                     FEVNKLIWVKQPGA"
                     /name="lipocalin family protein"
     gene            complement(16910..18055)
                     /locus_tag="KNN07_RS24775"
                     /old_locus_tag="KNN07_24775"
     CDS             complement(16910..18055)
                     /locus_tag="KNN07_RS24775"
                     /old_locus_tag="KNN07_24775"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extended-spectrum class C beta-lactamase CMY-42"
                     /protein_id="WP_039023136.1"
                     /translation="MMKKSLCCALLLTASFSTFAAAKTEQQIADIVNRTITPLMQEQAI
                     PGMAVAVIYQGKPYYFTWGKADIANNHPVTQQTLFELGSVSKTFNGVLGGDAIARGEIK
                     LSDPVTKYWPELTGKQWQGIRLLHLATYTAGGLPLQIPDDVRDKAALLHFYQNWQPQWT
                     PGAKRLYANSSIGLFGALAVKPSGMSYEEAMTRRVLQPLKLAHTWITVPQNEQKDYAWG
                     YREGKPVHSSPGQLDAEAYGVKSSVIDMARWVQANMDASHVQEKTLQQGIALAQSRYWR
                     IGDMYQGLGWEMLNWPLKADSIINGSDSKVALAALPAVEVNPPAPAVKASWVHKTGSTG
                     GFGSYVAFVPEKNLGIVMLANKSYPNPVRVEAAWRILEKLQ"
                     /name="extended-spectrum class C beta-lactamase CMY-42"
     gene            complement(18508..19205)
                     /locus_tag="KNN07_RS24780"
                     /old_locus_tag="KNN07_24780"
     CDS             complement(join(18508..18956,18956..19205))
                     /locus_tag="KNN07_RS24780"
                     /old_locus_tag="KNN07_24780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558260.1"
                     /ribosomal_slippage=""
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1-like element IS1B family transposase"
                     /protein_id="WP_095033700.1"
                     /translation="MASVSISCPSCSATDGVVRNGKSTAGHQRYLCSHCRKTWQLQFTY
                     TASQPGTHQKIIDMAMNGVGCRATARIMGVGLNTIFRHFKKLRPQSVTSRIQPGSDVIV
                     CAEMDEQWGYVGAKSRQRWLFYAYDRLRKTVVAHVFGERTMATLGRLMSLLSPFDVVIW
                     MTDGWPLYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSFSKSVELHDKVI
                     GHYLNIKHYQ"
                     /name="IS1-like element IS1B family transposase"
     gene            <19260..19358
                     /locus_tag="KNN07_RS25165"
                     /pseudo=""
     CDS             <19260..19358
                     /locus_tag="KNN07_RS25165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001480010.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutE"
                     /name="ethanolamine utilization protein EutE"
     gene            complement(19430..19639)
                     /locus_tag="KNN07_RS24785"
                     /old_locus_tag="KNN07_24785"
     CDS             complement(19430..19639)
                     /locus_tag="KNN07_RS24785"
                     /old_locus_tag="KNN07_24785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062602.1"
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="WP_000062603.1"
                     /translation="MSMPPAIANTFLFEMMKSKSKDVTLAAIYALGEGRCQAENITREL
                     HRLSQSDDMEIKIAAIKALGRIYR"
                     /name="HEAT repeat domain-containing protein"
     gene            20031..20207
                     /locus_tag="KNN07_RS24790"
                     /old_locus_tag="KNN07_24790"
     CDS             20031..20207
                     /locus_tag="KNN07_RS24790"
                     /old_locus_tag="KNN07_24790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001054900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001054897.1"
                     /translation="MNLVDAFVKKVISEPYEEYGKWWIDVEYISWGVPGKTRLMFESKE
                     QALEVKEGYKFLT"
                     /name="hypothetical protein"
     gene            complement(20272..20367)
                     /gene="dqlB"
                     /locus_tag="KNN07_RS25275"
     CDS             complement(20272..20367)
                     /gene="dqlB"
                     /locus_tag="KNN07_RS25275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinQ-like type I toxin DqlB"
                     /protein_id="WP_000609148.1"
                     /translation="MINLLIIVLRAVVAVANALIAVLELIRELID"
                     /name="dqlB"
     gene            20868..21119
                     /locus_tag="KNN07_RS24800"
                     /old_locus_tag="KNN07_24800"
     CDS             20868..21119
                     /locus_tag="KNN07_RS24800"
                     /old_locus_tag="KNN07_24800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001291964.1"
                     /translation="MSEKWSKEFDSCFQVGSIEEIADALEKRSGSEENALAMLAMTAFT
                     LMTRRGICEMQNVAPDGKGIRLELIGFRENETIPDTLH"
                     /name="hypothetical protein"
     gene            complement(21191..21343)
                     /locus_tag="KNN07_RS24805"
                     /old_locus_tag="KNN07_24805"
     CDS             complement(21191..21343)
                     /locus_tag="KNN07_RS24805"
                     /old_locus_tag="KNN07_24805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001618166.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hok/Gef family protein"
                     /protein_id="WP_001387489.1"
                     /translation="MPQRTFLMMLIVVCVTILCFVWMVRDSLCGLRLQQGNTVLVATLA
                     YEVKR"
                     /name="Hok/Gef family protein"
     gene            21664..22038
                     /locus_tag="KNN07_RS24810"
                     /old_locus_tag="KNN07_24810"
     CDS             21664..22038
                     /locus_tag="KNN07_RS24810"
                     /old_locus_tag="KNN07_24810"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_223349261.1"
                     /translation="MSQLKQPIFLKKIKKVINTIPGLEEQIFACRNKKRSDNPLLFIDR
                     KDEERILMSRLQSQQKNEELASKLESLFHGNELSSPHSILCFIYWRYTKKIYRLSEDII
                     SDVANTYVDNLDSTSVLQKA"
                     /name="hypothetical protein"
     gene            22191..>23348
                     /locus_tag="KNN07_RS24815"
                     /old_locus_tag="KNN07_24815"
                     /pseudo=""
     CDS             22191..>23348
                     /locus_tag="KNN07_RS24815"
                     /old_locus_tag="KNN07_24815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_031587700.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISEcp1 family transposase"
                     /name="IS1380-like element ISEcp1 family transposase"
     gene            23404..24101
                     /locus_tag="KNN07_RS24820"
                     /old_locus_tag="KNN07_24820"
     CDS             join(23404..23653,23653..24101)
                     /locus_tag="KNN07_RS24820"
                     /old_locus_tag="KNN07_24820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558260.1"
                     /ribosomal_slippage=""
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1-like element IS1B family transposase"
                     /protein_id="WP_095033700.1"
                     /translation="MASVSISCPSCSATDGVVRNGKSTAGHQRYLCSHCRKTWQLQFTY
                     TASQPGTHQKIIDMAMNGVGCRATARIMGVGLNTIFRHFKKLRPQSVTSRIQPGSDVIV
                     CAEMDEQWGYVGAKSRQRWLFYAYDRLRKTVVAHVFGERTMATLGRLMSLLSPFDVVIW
                     MTDGWPLYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSFSKSVELHDKVI
                     GHYLNIKHYQ"
                     /name="IS1-like element IS1B family transposase"
     gene            complement(24112..24420)
                     /locus_tag="KNN07_RS24825"
                     /old_locus_tag="KNN07_24825"
     CDS             complement(24112..24420)
                     /locus_tag="KNN07_RS24825"
                     /old_locus_tag="KNN07_24825"
                     /inference="COORDINATES: protein motif:HMM:NF014417.2"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination NusG
                     family protein"
                     /protein_id="WP_039023235.1"
                     /translation="MNIEHLNNRNWYLAQYNTAGKNRESLFSWLNEQNVVPWTPLITRK
                     IRRADSRCCHRERIFAIFPGYFFILANFDIQPVSALRRHSAFIDFVKFGGEIKPVNR"
                     /name="transcription termination/antitermination NusG
                     family protein"
     gene            complement(24862..25149)
                     /locus_tag="KNN07_RS24830"
                     /old_locus_tag="KNN07_24830"
     CDS             complement(24862..25149)
                     /locus_tag="KNN07_RS24830"
                     /old_locus_tag="KNN07_24830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraA"
                     /protein_id="WP_000074855.1"
                     /translation="MSPQMIQKLPAITLLEGMFPELSTNQLKVCVFYAMGVPYDAIAQN
                     CRLSPETVRTYLKRSLKNLNLEGYDALRSAVLMRTFVFMISNTAKENEKM"
                     /name="conjugal transfer protein TraA"
     gene            complement(<25187..25345)
                     /locus_tag="KNN07_RS25170"
                     /pseudo=""
     CDS             complement(<25187..25345)
                     /locus_tag="KNN07_RS25170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000980235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ash family protein"
                     /name="ash family protein"
     ARG             complement(16914..18055)
                     /name="blaCMY-42"
                     /gene="blaCMY-42"
                     /gene_name="extended-spectrum class C beta-lactamase
                     CMY-42"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          47..1077
                     /name="IncI-gamma/K1"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gtgtataaat acacggcaca atcgctccgc cataagcgac agcttgtggc aggtctgaag
       61 aatactccat ataacgcagt acactggagt cagttagcac ccgaagagca gatccgtttc
      121 tgggaagact atgaagcggg aagggcgacc actttcctgg ttgaaccgga aaggaagcgc
      181 acgaagcgcc gtcgcggtga gcactccacc aaacccaaat gcgaaaatcc gtcctggtat
      241 cgtcctgagc tctataaggc gctgagcggg cagctcgggc acgcctacaa ccgtctggtg
      301 aaaaaggacc cagtgaccgg cgagcagagc ctgcgcatgc acatgtctct gcatcctttt
      361 tacgtgcaga aacgaacgta tgccggtcgc aaatatgctt tccgtccgga aaaacaacgc
      421 ctcctcgatg ccatctggcc ggttctggtc agcttcagtg atgcgggcac acataccgta
      481 ggcatgagtg tttcccgtct ggccagagaa atcagcccga aagacagcaa ggggaaggtt
      541 attccggaac tggaagtgac ggtctcccgc ctttcccgtt tgctggccga acaggtacgt
      601 tttggtgtgc tgggtgtttc agaggaaacc ctgtgggacc gtgaaacccg ccagcgtctg
      661 ccacgttacg tctggataac accggcaggc tggcagatgc tgggcgtcga catggtgaaa
      721 cttcacgaac agcagcagaa gcggttgcgt gaaagtgaaa tccgccagca actcatccgg
      781 gaaggcgtac tgcgtgagga tgaagatatc tccgtacatg cggccagaaa acgctggtat
      841 ctgcagcgca gccaggatgc actgaaacac cgtcgtgcaa aagcggcagc cagtaagcgc
      901 gccagacgtc tgaagaaact gcctgccgac cagcagattc atgagatggc agagtatctc
      961 aggaagcgtc tgccgccgga tgaagcctat ttttgttccg atgaccatct gaagcgactg
     1021 gccatcaggg agttgcgtca gcttgaactg acgctggctg cgccaccgcc gcactagaca
     1081 gcaccattcc ttcagcactg aatcatcgcc agcccctccg gggctttcgg cgctggttcc
     1141 gctcagccca aaatctgcag taatcacctt aaatcccctc agaggggcat atctgtccat
     1201 aaaaccacgt atcagtcatc agaacatggc cacgttgttt cagttatcca cataaatccg
     1261 caaacaaaga actttaaaaa gctgcaaacc tgaaacagca aacctgcaat atagtcctac
     1321 ccccattatt taatcccctg cgttgcttcg ccgcagggaa agtctttatc tctgaaacca
     1381 ctgtgaacaa atacagagag gccttcgctt gcagcggcca aggccgcgcc gctcagaatc
     1441 taaaagcacc tcccacgctg acgcgcgggc cccgaacctc accgttctga aaccacaaca
     1501 aaaagacatc aggaataaaa acaccgcaca aacgcagcac cgtgcctacc cctcataact
     1561 gaaaagcgag gccgcccccg cccaaagggc gggaacaaca tcgcttttaa ttatgaatgt
     1621 tgtaactaca ttatcatcgc tgccagtctt ctggctggaa gtcctccgta cacgctcgta
     1681 agcggccctg acggcccgct aacgcggaga tacgccccga cttcgggtaa accctcgtcg
     1741 ggaccactcc gaccgcgcac agaagctctc tcatggctga aaacgggtat ggtctggcag
     1801 ggctggggat gggtaaggtg aaatctatca gtccgtaccg gcttacgccg ggcttcggcg
     1861 gttttactcc tgtgtcatat gcaacaacag agtgccgcct tccatgccgc tgacgcggca
     1921 tatcctggtg acgatatctg aatcgttata tactgtgtat aatatatggt gcgttaattt
     1981 ttaaaccctt atttaatttc ctcgtcagtt agatattgtc cgtttcccaa acgaagccct
     2041 tcagagacgt cgtgtaaaca cggtcctttt atcttacagg ttaaccccta tcaatcttag
     2101 gatgaaacca cgccatcctc tgcttgcctg gttattaatt tcatatcatc ttatgccttt
     2161 tttatcttca tttgggaccg tacttttctt cggaatatca ctattcgtta actgctgttc
     2221 atcaataaaa ttcctgatga tattcagttc actctgacgg attttttctt cttcattttt
     2281 tctcagaaga cggcagatat ccatttcatc ccgcccggtc attctttttc cggaaaaaag
     2341 gcggttaagc agctcctgct ttacatctgg tgagtctttg gtggcctcca tgaggttgag
     2401 cagactctga cgatcgagaa tagagaaaac ttttgggaaa taatgtaaaa ggaaaagaac
     2461 ccagaatgct gtccatgcaa agcagagaaa agctgctgta agcacgtgat tcttgcctga
     2521 taggtatata atcagcagaa caaccgaaat ccaagatgcc agttctaaaa aagtatatac
     2581 aggcttcagg cgtctgtatg cctgttcatg attattcagg atgaattgaa ttttttctgc
     2641 acctgattta ctcataataa ttctcttccc atttttctga tacgtaatgt ccagctgtta
     2701 tcaggagtgt ttattgccca gaaatattct cctgctgtgc ctgcatcctg agcaactttt
     2761 gttctaatgt caccagtctg cgaccggcac tctgtgcttc agattctgag acctgccctt
     2821 tggggtgacc atccagacca taacgtggga cgccggcgac agctgtccgc tgcagatata
     2881 cacggcgtga ggtgatgcag gacactgcac agagccattc gtccatggtc agttctgtct
     2941 ccgggtgttc tgccagaaat gctgaaatat cattgtttat gccaattttc aggggaataa
     3001 atccaccacc ttcagcacga agatgaggaa acaggatctt tattttttcc acgcactcgt
     3061 gagtatactc tctggtccag tgggagggac gtgggaaacg gcgttttttc tttttcttct
     3121 tcctggctgg tgcttcgggg atatgtgttt cgacggcaga tgaatttatt ccgacggggg
     3181 ctgattctgc tgcctgttca gtaaatgcag attcgataat atctgttttt tcggataagg
     3241 aaggtaacga aaaggtacga cgttttttca ctacaatgac ggggattttc ctttcttcct
     3301 gatttttttc cataaatacc tcggctggct ggttttactc tttaataata tcacaatcca
     3361 taaattagta aattttccgt caggtgattt ttcatggttt ataagtccgt tctctgaata
     3421 tttatactcg aggcggtaac agttatggcg tgacagtcga attgatattc gactgaaccc
     3481 tgaccgaaac atggttgata tattctctaa cgttaatgtt gtcatgatat aaataaaaaa
     3541 aattcatttg aaaggatgtc agaagaagat atcggggcgc acagttcatc tctgcctttg
     3601 tttcatggtg tgttctttgt atattttact tactgtttaa gcatgtacat aaggagtgct
     3661 ttcattatgc caatgatact tgtaaagaag aatccccggg gcaaagtgat tcgggagctt
     3721 agcagtgagg aagagactgc agtaaagacg gtctgtggac tgaaaaagcc agcaaccatg
     3781 gcacaacata acctggccaa tgatcttctc cgggaaatgc gtgagtatga tgcatggtta
     3841 cagtgtgact gtattccggg agattcgccg gccatgaatt ttgctgctct taaaaacaat
     3901 acgggtactc tttatctgtc cagttttaat catgagcatg cacctgaatg ccccatgtat
     3961 cgtcagttat caggaaatga agaggaaaca tccttcggag caagccggca tcccgttagc
     4021 acccgtataa attacagaaa ctttttacca cctgatgaca gtaattctgt tatcagactg
     4081 cagacccgct ctgcttacca taatggtgag cgctcctccg ttcgcaagaa acgtccgcgc
     4141 cttggccgtt tactcctgtc gcttattgaa gatgcagggc tgaataaact ggattccctg
     4201 gctaatcccc gtatccggac taattatcgt gagtgtcttg atgccatacg gcaggttaca
     4261 ctacagcagg agtatattcg gggaagatcc ttatctgaaa ttatccattt ccggccagga
     4321 atgtctgaaa ggtctcagga gcggttaatg gaaacgctgg agaattcaga acgacactgg
     4381 cctgccagaa gaaaacatat gttctttcag atttttatgg cgcagcacat ctgtcgtgat
     4441 gctgtggaaa ttcactgggc gaacggtaat attcaggtct tcagacctgt gcgggggatc
     4501 agtattaatg gtgaagcgca gggcggaata cgtccccctt actgggttat tcttgctttt
     4561 tgccggagtg ccgatggcag aatcatctgc agtgaagggt atgctcatgc tctttatcaa
     4621 ctgacatgtc cggttcctgt ggacagcaaa ctggaacgaa acacgctcac tgctcttctg
     4681 aatgtggcca gctggcttaa aagaaagcca ggtacgccgg aattaagtct ggaaaggccc
     4741 ctgtttgata cagaagttta tgttaatggt gaaaagaaat atgtactgcc ggatttcatt
     4801 gtcacagcaa tggctcctga cggaaagacg gccagagtgg tcatcgaaac gatgggatat
     4861 gaagacagtg attactgcgc gagaaaatcc aggcagcata ccggcatgaa gcagattggt
     4921 gttctgcata ccgatccacc gaaatggctg gataacgatc atcccccttt tgagaaacat
     4981 atgtacggtg tttttatgca tctcaggtac tgagatattt tgtggctcag ttctgtaact
     5041 tttcccgtaa cattgtctgt tgttacggga aagtccggtt tttgtattgc accagagaat
     5101 actcagactg tgatgctgcc acagcgtcag caggctttct gaacggtgta acatcacttc
     5161 atgttaatga taatcactat cattaaatct tgacatgcca ttttctcctt aataaattaa
     5221 tactgtatat gtatccatat acgtaagcag ttaattcatt tgttttcctc agaggatgaa
     5281 ggagataccg aatgtctgat cctgtacggg gttcagtgag ttagctggcc tggatgtaac
     5341 cactcgttca actcaattct cttagcgtgg gaaaatttcc gcttttccaa gcggacccct
     5401 attaatattt gttttgtttt aggttctatt caacataggt catcctaaaa tacattgaag
     5461 ataacaagat aacaagataa caagataaca agataacaag ataacaagat aacaagataa
     5521 caagatagta aggtgttatc tttgttttac ttctgctatc aatcgtgata cctctgtttt
     5581 tgatagtgtt ttaagtgctt ctaccgccgc cctgacaaca tcagaacgat tcactctgcc
     5641 tttacctgaa accatctcag ccgttataag ggcatcaatg tcttttaggt tttcttcaaa
     5701 aaaagaaata ctcactggtt ttgctttgct tacaaccgat gatttatctg atgacttttt
     5761 ggtattatca aggccagccg tgccaccgtt aataaatgct gcctcgtcac gaggtgaagt
     5821 gtttgctcta tttctcacag aataacctct ttcactaacg cttcgatttc ttgctgggct
     5881 ttatcatttt gcgtttcaaa aattgtcatt gattcggccc aagcatctcg atgtgcttta
     5941 cgatcacata cccgggagtt tgccagatgc atttcagggt aatccttaag tacttcagct
     6001 gcctcattgg cttcattaac aaacatattt gtgggcgtca tgtttaaaac gagatatccc
     6061 cgaacatcct cattaaaatc ttttgctgct gtaaaaacgg agcatgtatg aggcacaaca
     6121 tccaggtcca tctgagatgg gcgcaaagga gaaatgaata catctgcggc catcaatcca
     6181 ctacgcattt ctgcgctatc acggccagca cagtctgcaa taacaaaatc ataggatttt
     6241 tcgtgttcct ttaacatggc tttgatgtta cctgtcgcgc ctgtaaccgg aatatgaggg
     6301 agatcttcag ggcgattgtt gtaccaggtt aatactgatt tctggtcatc tgcgtcgaca
     6361 ataatcactc tattgcctag tgacatcaga tacgcagcta tagataccgc cagtgtactt
     6421 ttacctaccc cacccttttg actacctaat actattatca ttatagcctc atattaagct
     6481 gttaagttaa caacttaata ttgccatctg aacgcgaacc atgcaattat ttttgttatg
     6541 ttaacaactt aacaagctgt taagtatttg atttatagat taattaagat aacaagataa
     6601 caagataaca agataacaag ataacaatat tatgggtgga ttacatattc ataactgggc
     6661 tactggcaaa tctgtccatc tggtggtata cgcaggagaa agcatttccc gtttcatttg
     6721 ccactcaggg gcggttcctc gccccgcaaa ccacactgtc ccttttcccg actggttcag
     6781 ttcatcgagt gttttcatta acttttcact gtttttacgg ggctggattt catcaaataa
     6841 tcccggctgt gctatacccg atggtgtgaa atcagccagc atgactcctg ccttcatata
     6901 gcggtaccct tcacgccaga catggtttaa ggctctgcat gcggcggcaa taatgtcccg
     6961 gctgtcctgt gtgggcaatg gaagcttttc cacagcggca ttgctgtaac agggttcttt
     7021 tactgcaaag ggggatgtcc gtacaaatgt cgtcacctgc cggcaatact gacgctcccc
     7081 acgtagtttc tctgcggccc gctctgcata ctgaacaaca gcctggtgca tggcatcttt
     7141 gtctgtgatt cgttcaccaa aactgcgact acagacaatc tgctgttttg ccggtggtgc
     7201 ttcttccagg gatatgcagg actcgccgtt gagttcgcgt accgtacgct caagaatgac
     7261 gctgaagttt ttccggatga atgccgtgtt agcctgcgcc agctgcagtg ctgtgttaat
     7321 acccagcgca ttcagctttt ccgtcagtct gcgtcctact ccccagacct caccaactgg
     7381 ctgcagcccc agtagcttca aggtccgatt acggttttct gccgtcagcg cgaccactcc
     7441 ggaaaactgt ggccattgct ttgttgccca ctgtgcactt ttagccagcg tttttgtagg
     7501 cgcaatgccc acccccatgg tgagtcctgt ccagctcttt acctgttccc tgagctgatg
     7561 accaaaaaaa tccggagaga tgcaatgatt tatcccccgc aaatcaataa acatttcatc
     7621 aattgagtag ggctcaactg cgggagaaag cgactccaga acagccatga cccgttggct
     7681 catgctgtgg tacagcgcat aattgctgga aaatacatgt attttcttct ccaggcgcat
     7741 ctgtctcacc tgaaaccagg gctgccccat tttgatgcca agggcttttg cctccgggct
     7801 gcgcgcgatc acacagccat cgttattgct gagtacgatg accggttcgt tgcgaaggtc
     7861 cgggcggaaa actttttcac atgaggcgta gaaactgttg atatcagcca gtgcaaacat
     7921 cagcgtaact cccgcgtcct gtgtatcacg tgagtgacaa caccaaaaat acagatgttt
     7981 tccggataca gtgtgcggaa ctccgggctg tctgaaaccg gctccagtgc cgggcgtggg
     8041 cgcaacagca gtcgtttgac ggtgaactca ccgtcgatct cagcgataac gatgtccccg
     8101 tgttgtggtt tttcggccct gtccactacc agcagatcac cattctgcac gccagcctgg
     8161 ttcatcgatt caccgctggc gcgcagaaag aaggtggctg caggtctgct gatgcaatag
     8221 ctgttcagat ccagttcctg ctcagcataa tcagtggcag gcgaaggaaa accggcctgg
     8281 caacgatcgg caaactgggt ttgttgaagt cgagatctat gtgggaaaca ggaaaccaat
     8341 aacgcagaac gattgaagcg ttattcccgt aatagcacaa gaaatccgcc ctacgttgat
     8401 tgtgaccact ctaacgggcc agctattgat gaaatagtta aacgatcgaa agacatccta
     8461 agtacatcgc atctccacac cgtgaaacta cgggactacc taaactggat ttatacccag
     8521 catggtagcg gagtctccat agtactcaag gtcggcctgt aatgggctac ggcagtccgc
     8581 attatacgga agcagcaaag gtataaatca accggaaggg agatgaaagc ctcacagtgc
     8641 tgcggggaag ggagacagtt gttagataca tcaatctcta agaggagggt tagccaatgc
     8701 tgcctgatga acttgagaaa agattagatg gaattgagga tgcttcaaaa aaagggtatc
     8761 cagtacgtaa tctatacaaa attgcgtgtg agcccggact gtggctgcaa gcctacgtga
     8821 atatacgggc caatgcaggt gcactgactc aaggtgtatc aacagatacc attgatggct
     8881 tctctatcga aagagcagag aagctggcaa aaacattgcg gagtagagaa tacgtagcga
     8941 aacctgtacg cagagttcag atcccaaaaa aggacggaaa aaccagaccg ctggggattc
     9001 caggtggaga cgataaactg gcgcaagaag tagcaagaat tattctggaa agggtttatg
     9061 aaccagtatt ctctgaacac tctcatggat tcagaccaaa acgttcgtgt gaaactgcgc
     9121 tcagatctat tcgtccagtc tggaacggag ttaaatggat cgtggatgtt gatatcaaag
     9181 gtttctttga caatatcccc cacaaactat tgctgaatac actggcagag aaaattaagg
     9241 ataagaattt cctgaaatta atcgaacagt ggctgaaggc aggatatgtg gacaattgga
     9301 aataccatcg ctcatattct ggcacgccac aaggtgggat aatttctccc ttactggcaa
     9361 atatatacct cgacaaactg gaccgttttg tagaacagaa cttaattcct gcatatacaa
     9421 gcggtacaaa acgaagagcg aatccagata tgaacaggct ggcccataag attcataaac
     9481 tacgaaagaa agtagacggt atggcaactg attctgaatc agaaaaagaa gccataaaga
     9541 aagaaattga acgactgctt gaagaaaaac gttctatacc atctcaggtc atgaacgatc
     9601 caaacttcag gcgtatgtac tatgttcgat atgctgatga cttcgtaatt ggtgtcatcg
     9661 gctcgaagaa agatgctgaa catatatcaa gacaggtcag aaactttatt actacttcac
     9721 tgggattgga agttaatgaa gcaaagacca ggatccgcca tatctcagaa ggagttaatt
     9781 ttttaggcta tgaaatcaga caggcagatg caaagaaatt gctgaagcag aaaatgcaag
     9841 ggcggcacgc tctccggaga tccaccacag gaattgtgca gctcttcgtt cctgacaata
     9901 tagccgctaa attttgtcac caaaagaaat atggctgtta tgagaatgtg aaggctgtac
     9961 atcgttcaag tctacaaaat ctcagtgaag ctgaaattgt tctgactttc aacgcggaaa
    10021 tgcgcggatt ggcgaactac tacagtctgg cgctggacat gaaatataaa ttatcaaaat
    10081 tatatttcat atggcaaata agccttttta agaccctagc gaataaacga cgtagttcag
    10141 tgaataaagt cgccaaatcg ctacggcaaa ataatggaga tctggctatt accgttcagg
    10201 ccaaaaatgg atcccgaaag attgaggttt tcaaactcaa acatgtcaat cgcaaccgaa
    10261 caacgattgt cgatacggaa ccgagaaccg cacatatcac aacccgcaca acagagatca
    10321 tgcgtcgatt aggggcaagg atctgcgagt attgtgcgaa gactgggcgc tgcgaagtac
    10381 atcatgtcag aaagctaaaa gacctgaaga aaggtcgtaa ggccggatat aaacccagcc
    10441 tgtggcaact aatgatgatc gcacgccgcc ggaaaacgat gattttgtgc gcaagttgcc
    10501 acgacaagtt acatagcgga aaactacccg atctgagaca ggaaaaggga agaatactcc
    10561 tgcaaccacc tgtctcaagt ggggattctg ctaaatgagt ttatccccaa taagctagca
    10621 atggagagcc gtatgcattg aaaggtgcac gtacggttcg gagggggggt aacggtgatc
    10681 taactcaaga taagcaggac atattcgcca tttatcttga aagaccacac gtaccctacc
    10741 ctaccgtctg ggtaatgatc cggaagtccg ttacatcccc aaaccggatg tgcgggttat
    10801 ccgcaatctg attacggaaa gtgaagtggc ggtggcgggg aacagtaaat tccgcttcgt
    10861 gggggctgat gccttctcgc cagacgaact gcgcaccgat ttgttcagcg acgacgaggg
    10921 tggctatgtg gactgcgtgg cgctcgatgc cgccctgctg gaaaaactcc aggctgtcgc
    10981 agagttcctt cgggaagccg aaggctggga atggtgcgcc ggacgcatgg agcctgtcgg
    11041 tgagtgccgt gaggatgccg gaacataccg ctgtctgccg gagccggaag cggtgctgac
    11101 cgaggcggaa gaagaacgtc tgaacgaact gatggcacgt tacgacgcgc tggaaaacca
    11161 gtgtgaggaa tctgacctgc tggaagcaga aatgaagctg atgcgctgca tggcgaaggt
    11221 cagagcgtgg acgccggaga tgcgtgccgg aggtggagtg gtggtgtcct ggcgttatgg
    11281 caacgtgtgt gtccagcgtg gtgtgcagtt gcgcagtgaa gatgacgcga ctgatgacgc
    11341 tgaccgcacg gaacaggtgc aggagaaagc gtcagtggag gcaatcagtc tgccgttgct
    11401 gacgaaaatg tcttccgaac gcacgctggc agtccaggca gcactgatgc agcaaccgga
    11461 caaatctctt gcactgttgg catggacgct ctgcctgaat gtgtttgaca gcggagcgta
    11521 cagtaaacca gcacaaatca gcctggaatg taaacattat tcgctgacca gcgatgcgcc
    11581 gtcagggaag gaaggtgccg cattcctggc gctgatggca gaaaaagccc gtcttgcggc
    11641 cctgttaccg gagggatggt cacgggacat gacagagcag aaatacagcc gccagcggga
    11701 acgtgaggca gaacgacggg aactggaata ccagacatgt tttgctcagg cgcagattga
    11761 ccttgcgttt catactcccg ccacggtcgg aagctggttg tcccgctggt ctggtgttgt
    11821 tgaggagcat gatctggaaa cgattttctg ggggtggtgc gggcgttttc catcactgtc
    11881 atcatttgac cggtttttct ggcaggagga accactctgg cggctgattt ttgaagccgg
    11941 tgaggccggt cgtggtgcac cggtacaggt acgtgcactt gagcagtgga tgatcccgaa
    12001 caagctggag aacgtaatat gatgaaatca gacgaaaaat accaggttcc cgcgtggatg
    12061 cgacctctgt tgccgttgct ctgcaacacc ggggggaacg atccggaaga actgctgaat
    12121 gatacagaaa ccactgccag tgcgaatgtt gtccgttatg tactgatagt tgctgtgcgg
    12181 tcgcaggttg atctgctgca gcttctgtac aggaaagggc tgttgcgcac agagatacca
    12241 ggtggctttt caccggaaga agcgcaggca ctcctggata atctggtgcg cagccatatc
    12301 agcaaggcgc tgtcgggcga gcgaatggca gcccgtgaca gaaatgccga tctggcctgg
    12361 attggacagc aactggtcga tgccgcctgg tttgtccgtg ccacactgga agcgcatggg
    12421 atgagcgtcg gaaatgagag tccccctgct ccgccggaga caatgccgga catacagaca
    12481 cgggaactgg tgatgttgat caagcgactg gcatcatcgc tgaaagcggt gaaaccggac
    12541 agttgtgtgg tgcgtgaagc gcaggactgg ctgcgcgaca gaaaacttgt ggatatcaca
    12601 gatattctcc ggtgaaccag gcatgtatat tttacgcagg gacacgccga tcatgatcgt
    12661 ttcatatcag gggtggtctg gaggtcatgc ggcgtgtcct ctgcactcgc cggaataagg
    12721 aagtcgccgg cggctccgct tttacccggc catgcggggc atggccttgt gggttttcag
    12781 ctctgtggcc tcagcgtcgt gtgcgggctg tgccgtgcct ccatcttagc cgggctggca
    12841 gggatgcaag ggtacgcttc gccgctgcgg tcacccggtc cctccttccc gtctgccgtg
    12901 attttccggt cgttcgtccg ctcaggtttc gcggcctcac cctgcaactc ccgtcagccg
    12961 tgtgcgtcag gctgcggctt cccttgcgcc cctgcatccc cgccttatcg cccggctttt
    13021 atggaggcac ggcaccgccc ggtgtcgcag aacatgtgac tatggaggat tcgggaatgt
    13081 ctgttgttgc acctgctgta gcggaacaga gagacggcaa tcattgccat tacgaacagt
    13141 acaacgctgg cgattattgc acggaacaaa ggcgttctgc tgaagcggcg ttccatcagg
    13201 tattcaaggc gcagacagga atcaatagct gtaagtatct ggtcagcgtt atgctcctgc
    13261 ttgtcaatca ggacggtttc tctgttacga gtgcccatgg cgtcaaaggc tatatgaatc
    13321 agttgattgt ttcgtgttac cagccctgac agggcatcct gtggaaggac ggcaataatt
    13381 tctgtcctgc cacccggcca gattgcctgc acggaaatat gttttgcaat gcgtgttgca
    13441 aagtactcga ttgtcatttt cagttctccg gataatcaga attcgttgtc tgtagcaggt
    13501 gtgcggggca ggatgtcgtc ggtgagggac cagttggtca gaatgcggcg tttccggtcg
    13561 cgatctggtt gtggttcatc ccagataaga ccgagactga gcatatcccg ccgtaagcct
    13621 tccaccgctt catcaacaca gggttcaggg cagggaaggc caaaacgcat ggcttcggcc
    13681 tctgcacgtg caacggccac cacgccagcg ccttcaataa atcctttcgt ggtattggcg
    13741 cggtgtaatg cataaaacag cgttctgtcc acgcctttca gccaaatcca gttgggtggc
    13801 gtaagccgca agtcatgtgc atacagccag accagcccac tgcggacgta gcgatgttgt
    13861 ttcagccatt gctgtgctcc gtcgctttta atcactcttt tgaatgcaga tttggccagt
    13921 gaataaacag gggtacagaa tttcccactg tcccgtttgc ttttaattct gcatgagagg
    13981 ttcagtgtat ccatgagctt taatgctgcc ttacgatcat ccaggaaata ctgaaggcca
    14041 aatatggcaa agagcgcttt ttcatgtggt gccatgtctt tccaggacgt taaaggttta
    14101 cccaactggg ccatgaaaca tcgtcttgca gctgcaacat cgagctgcat attggtgatg
    14161 agagtatgct gttcgacaaa tgcttccggg gtgagagcaa cccgccgttc aggtcgtttg
    14221 ccaccatgaa agagtttttc cggatcacca tcttccagta caggggcgat agcaggggac
    14281 aacgaagcaa agatgtgtgg cagtcgggta atatctactg gtctgcgggt gaaacggctt
    14341 tgtcccggat gttgatacca ttcccacaaa caccagagtg tcacaggtaa gaggtacatc
    14401 cacaaaatac ctatggtctg ctccatgacg ttaacccact ggctatagct tatgttggcg
    14461 gcgttgttac cggtcatggc aagcaggttg tatcgtggtg ctgcatagtt atgaaatggt
    14521 ccccagtcaa ccagtcccca taaggtatga agaatcaggc agctggcgta aaccacttcc
    14581 ggcaagaata accatatgac gaatagcagc aggataagaa ggacaccaac agcgccccat
    14641 atctgcatcg gatcttctgc gacaggctgt cgattgtaag acatggcaaa gtctccattt
    14701 ctggaattta aatcaaacgg aaaggttaaa aatttatttt caggtgataa gagctaacca
    14761 gaggagttag ccgtgcgata aaaggattgt tgcagatacg aaagtcgtta gaatagccgc
    14821 ggacgcttga ggctgtatgc cgaaagcgtt ttgtggacgg tatacagcag aaagcccctg
    14881 gagatttttt tatcaatcaa ccaagggctc tactgtaatg catgaacaac attacagtag
    14941 cctgataatt tagatatgtg tacatcctac cggaaaagat acttctcagg tcatttatca
    15001 atgggcgtta ttaccaccgg tagtttgttt acgtcttcta aattaactgg taccggaggt
    15061 aaccatatta atctaggttt acgctcatgg gctagttctg gtttcttact tcctgtccag
    15121 tatgtatgcc agtgtccccg gcgtatatga ggacgtttgc tacctattgt tgtccgctct
    15181 ttccctgtgg gttctgcttg gcgatattgc cgtatggctt gccccattcg aataccaacg
    15241 tcccactccc gaatgttttg tgctggtagt tcatggtgag tgtgaacatg ctttttgtgc
    15301 ttttctgacc gtttaaattg atttttttct tttatatcat tgatctgtga acagatataa
    15361 agcaccattg atatctgtgc gttaagaaga ttaaactccc tgtctctgaa atctttgagc
    15421 ttttcgttaa ctgttacgac gacttcacca tcgatacact ccatctttct ggagtcaaga
    15481 agtccttcac gagagtcctt tattctgatg atattattga cgacgtcaac attcttttct
    15541 tttagccctg tagttccttg actttgtttc agatcatcaa taatgaaaag ccggataata
    15601 tttccattat tgtccaaaaa tggataaaag aaaaatccat gtatcggata ggacgtagga
    15661 agtatagtat gcagattttc ggctgaaaca tagatactcc atgaagggag ttccttgagg
    15721 atctgtgcag gaatgttatc tcgactttct ggtttcagaa agcccttcat catagagaac
    15781 tccgatgagt gccaaatgcg ggaactacgc cgctaattat gcttaattct tgcttttagc
    15841 aggcggtgaa taaaaaggtt gaaattcatt ttcttccggg caaaaatgcc atttcacaca
    15901 ttagctttgc aggacgacct gcaaacgctt ctttcaccgg ggacggcccc attgttctgg
    15961 agcctgatat gtcctggatc gttttattaa ttgcaggttt gctcgaagtt gtctgggcga
    16021 ttggcctgaa atacacccac ggttttacgc gtcttacgcc aagcattatc actattgcgg
    16081 cgatgatcgt cagtatcgcc atgctctctt gggcaatgcg cacgttgcct gtaggaaccg
    16141 cttatgcggt ctggaccggt attggcgctg ttggggcggc cattacaggg attttgctgc
    16201 tgggtgagtc tgccagcccg gcacgtttgc tgagccttgg gctgatcgtt gctggcatta
    16261 ttggtctgaa gctgagcact cactaagcgc caggctgttt cacccaaatc agtttattca
    16321 cttcaaaccc ttcccgggtc gcgatggcta acatttgctg tttcatttca tctgaaatag
    16381 taggggtccg tgaaaggatc cacaggtagt cgcgatccgg accacaaacc agcgcgtgac
    16441 gatattcccg gtcgagtgca attacgttat acccgccata gaaggggccg aaaaaagaaa
    16501 ccttaagcgc ggctctgctt gggtcgccgg tgaaataggc tttcccttcc gttttctgcc
    16561 acatctccct gtcagggtta tagcccttgt taataacgtt gatgccgccg tcgtcgcgca
    16621 agctgtatgt tgcggtcact ttatccaatc cgcgctcgaa acgatggtcg aagcgcgcaa
    16681 tttcatacca ggttcccaga tagcgtttgg catcaaagtt atttaccacg gtaacgcctt
    16741 tcggcggtgt cggggagcta cacgcgacaa ccaggaatgc agccgtaact gcagcaacga
    16801 cgggcaaaat gcgcatggga ttttccttgc tgtatttttg ttaagtgtag atgacaacag
    16861 gaaaaaaaga gaaagaaagg aggcccaata tcctgggcct catcgtcagt tattgcagct
    16921 tttcaagaat gcgccaggcc gcctcgacac ggacagggtt aggatagctt ttgtttgcca
    16981 gcatcacgat gccaaggttt ttttctggaa cgaaggctac gtagctgcca aatccaccag
    17041 tggagcccgt tttatgcacc catgaggctt tcactgcggg ggcgggcggg tttacctcaa
    17101 cggcgggaag cgctgccaat gccactttgc tgtcgctgcc gttgatgatc gaatcagctt
    17161 tcagcggcca gttcagcatc tcccagccta atccctggta catatcgcca atacgccagt
    17221 agcgagactg cgcaagcgca atgccctgct ggagcgtttt ctcctgaacg tggctggcat
    17281 ccatgttggc ctgaacccag cgggccatat caataacgct ggatttcacg ccataggctt
    17341 cggcgtcaag ttgtcccgga gaactgtgta cgggcttccc ttcgcgatag ccccaggcat
    17401 aatctttttg ttcgttctgc ggaaccgtaa tccaggtatg cgccagtttt aatggttgca
    17461 ggacgcgtct ggtcattgcc tcttcgtaac tcattcctga gggtttcacc gccagcgcgc
    17521 caaacagacc aatgctggag ttagcgtaaa gtcgcttagc gcccggagtc cattgcggct
    17581 gccagttttg ataaaaatgc agtaatgcgg ctttatccct aacgtcatcg gggatctgca
    17641 gcggtaggcc gcctgccgta taggtggcta agtgcagcag gcggataccc tgccactgtt
    17701 tgcctgtcag ttctggccag tatttcgtga ccggatcgct gagcttaatt tcgccgcggg
    17761 cgatagcatc gccgcccaac acgccgttaa acgtcttact aaccgatcct agctcaaaca
    17821 gcgtttgctg cgtgactggg tggttattgg cgatatcggc tttaccccag gtgaaataat
    17881 agggttttcc ctggtagata acggcaacgg ccatacccgg aatagcctgc tcctgcatca
    17941 acggggtgat ggtgcgatta acgatatcgg caatctgttg ttctgttttt gcggcagcaa
    18001 atgtggagaa agaggctgtc agcagcagag cgcagcataa cgattttttc atcatgaaat
    18061 cagttccgta attaaaagca aaaaggtgtc cgggcccgtc agacgcaatc agtgtgtttg
    18121 atttgcaccg tgttgacaaa cggttaaatt tagcagcaga tataagtttt tcctaaattc
    18181 cacgtgtgtt ttttattagc ttcaaaaatc actatttcac gaagaattta gactgcttct
    18241 cacacattgt aacattattt acaaccacct ttcaatcatt tttgataaat cattgatttc
    18301 atctttgctg caatgatact taataaactc tgcaagttat ccacagagca acactcaatt
    18361 ttattgatga tattcttatt ataccagaca tttttcatac actcccttgt acggatagtt
    18421 ttccgacaac ttcatgatta catatcttgc ggttttgatt atttttgctg caagaaatac
    18481 atacttcaaa cgggtaatga ctccaactta ttgatagtgt tttatgttca gataatgccc
    18541 gatgactttg tcatgcagct ccaccgattt tgagaacgac agcgacttcc gtcccagccg
    18601 tgccaggtgc tgcctcagat tcaggttatg ccgctcaatt cgctgcgtat atcgcttgct
    18661 gattacgtgc agctttccct tcaggcggga ttcatacagc ggccagccat ccgtcatcca
    18721 tatcaccacg tcaaagggtg acagcaggct cataagacgc cccagtgtcg ccatagtgcg
    18781 ttcaccgaat acgtgcgcaa caaccgtctt ccggagcctg tcatacgcgt aaaacagcca
    18841 gcgctggcgc gatttagccc cgacgtatcc ccactgttcg tccatttccg cgcagacgat
    18901 gacgtcactg cccggctgta tgcgcgaggt taccgactgc ggcctgagtt ttttaaatgg
    18961 cggaaaatcg tgttgaggcc aacgcccata atgcgggcgg ttgcccggca tccaacgcca
    19021 ttcatggcca tatcaatgat tttctggtgc gtaccgggtt gagaagcggt gtaagtgaac
    19081 tgcagttgcc atgttttacg gcagtgagag cagagatagc gctgatgtcc ggcggtgctt
    19141 ttgccgttac gcaccacccc gtcagtagct gaacaggagg gacagctgat agaaacagaa
    19201 gccactggag cacctcaaaa acaccatcat acactaaatc agtaagttgg cagcatcacc
    19261 gaggatatga ttaccctgtc gactttcctc gcctgattca ggaaaagcgt aaggagtggg
    19321 agcagattgc aggcatacct gtagccgaag tattttaaga taagctccct ccataacagc
    19381 cggttcaaat gagccggctt ttgttcatta caacagataa cttatgccgt taccgataaa
    19441 ttcgaccaag tgctttaatc gcagcaattt ttatttccat atcatcactt tgactcaatc
    19501 tatgtaattc acgagtaatg ttctccgcct gacaccggcc ttcacctaat gcatagatcg
    19561 cagcaagtgt aacgtctttt gatttactct tcatcatttc aaacaagaaa gtattagcta
    19621 tcgcaggagg catgctcata atcaatcctc ttcatgaaat aaacaatggc actcacttgc
    19681 aaacaggagt ccactatcgc aagcgactca acttagcaat atctctcaat ttgaatgaaa
    19741 aaaccagatg gcatgtgaca gggaaccgtc cgcatgatgt ccgtgaccat ttaaccccat
    19801 aagctaacct tgtcacaaac gggcgcagaa cagcctgcca gacagacaac aaaacaaaaa
    19861 tccaagataa aacatgaata ccggtatctc aatgcgaaga aataatctcc gtagaaaccc
    19921 ccatgagaaa aatatcatat gggagaaaat cgcaattatc acagccagcg cattcattat
    19981 tttcgctgtg ctctggcatt aattattttc aacacaaaaa ggaaaaaaca atgaatctgg
    20041 tagacgcctt tgtcaaaaaa gtaatatccg agccatatga agaatatgga aaatggtgga
    20101 tagatgttga atacatttca tggggtgttc ccgggaaaac aagactgatg tttgagtcaa
    20161 aggagcaggc actggaagtt aaagaagggt acaaattttt aacgtgagat ctctttttgt
    20221 taaagggcag gaagcggtaa ctccctgccc ttagttacgt ttccaggctt atcagtcgat
    20281 aagttcccgg atcagttcca gaacagcaat cagcgcgttt gcaacggcaa ctactgccct
    20341 gagaacgatg attaacagat taatcatccg cttctccatc actggagaaa gaaccccgtt
    20401 gttcgctctt acactgcctg tcacaacggt ttctatagtg tcagttatag acagttcttc
    20461 tccgaccaga gcaccaaaac cagcaccacc tgatgttttg gccaggactt gcaacctgtt
    20521 cttcccgctg aacaatatgt cggacagaac atgcctcaga gctgacatgc cgagtataca
    20581 cttatccagt acttgcagaa atataattcc agacgtacta tctacaagtc agttatagac
    20641 agttcttttc cgaccagagc cacccactct gtaacggaac agtaaaaaaa ccgacctcac
    20701 cagtcggttt ttttacatct gttgtttctc aaaatccgcc cgacatgccc gtcacaccgg
    20761 ggaaactcat gctttgaatc agaaccaatc atctcaactt tgccgtctcc tgaaaaaact
    20821 ggcacattca gttcgataac tacccataaa tacagagaga aaatccgatg tcagaaaagt
    20881 ggagtaaaga attcgactct tgctttcagg tggggagcat agaagaaatt gccgatgctc
    20941 tcgagaaacg cagcggaagc gaggaaaacg cgttagccat gctggcaatg acagccttca
    21001 cactcatgac ccgacgtggt atctgcgaaa tgcagaacgt ggcccccgat ggcaaaggca
    21061 ttcggctgga gctaatcggc ttcagggaaa atgaaacaat accagatacg cttcattgaa
    21121 gaagaaaggg cgcaatgagg tcagccttcg caacaaagcg gcggcagaaa acctgccgcc
    21181 gtgttgcccg ttaacgttta acttcgtagg ctaacgttgc cacaagcact gtgtttccct
    21241 gctggagccg gagtccgcaa agcgaatccc tcaccatcca gacaaaacac agaatcgtca
    21301 cacagacgac gattaacatc attaaaaacg ttcgctgtgg catcatagcc cctccattgc
    21361 cttccggcgg ttatcgggct actataatgt tgttgaggca ttacagtaga gcccttggtt
    21421 gattgataaa aaaatctcca ggggctttct gctgtatacc gtccacaaaa cgctttcggc
    21481 atacagcctc aagcgcccgc agctattcta acgactttcg tatctgtaac aatcctttta
    21541 ttatttgaat gattcagcgt tgtttttgaa gttaacaacc aacccaatac atggttctct
    21601 acttcacaac aacgcatgtt atgctgattt tagttaataa aagaatcccc ttaggagatg
    21661 gaaatgtcgc agttaaaaca acctattttc ctgaaaaaga taaaaaaagt catcaacaca
    21721 atccctgggc ttgaagagca aatctttgca tgccgaaata aaaaacgcag cgacaatcca
    21781 ttattattta tcgacagaaa agatgaagaa cgcatactaa tgagtcgtct ccagagccaa
    21841 caaaaaaatg aagaactggc ttctaaacta gaatctttat ttcatggaaa cgaattatcg
    21901 tcaccacaca gtattttgtg ttttatatac tggcgctata caaagaaaat ttatcgccta
    21961 agcgaggaca tcatcagtga tgtggctaac acctatgttg ataacctaga ttctacgtca
    22021 gtacttcaaa aagcataatc aaagccttga taaatatgca ttccttcgaa attcagcttt
    22081 cacccattgg gtgaaagaaa agtgctcaaa aatatgttaa attatcagct tttatgactc
    22141 gatatatggt aaaataatag taagaaaagt agtaaaaagg ggttctaatt atgattaata
    22201 aaattgattt caaagctaag aatctaacat caaatgcagg tctttttctg ctccttgaga
    22261 atgcaaaaag caatgggatt tttgatttta ttgaaaatga cctcgtattt gataatgact
    22321 caacaaataa aatcaagatg aatcatataa agaccatgct ctgcggtcac ttcattggca
    22381 ttgataagtt agaacgtcta aagctacttc aaaatgatcc cctcgtcaac gagtttgata
    22441 tttccgtaaa agaacctgaa acagtgtcac ggtttctagg aaacttcaac ttcaagacaa
    22501 cccaaatgtt tagagacatt aattttaaag tctttaaaaa actgctcact aaaagtaaat
    22561 tgacatccat tacgattgat attgatagta gtgtaattaa cgtagaaggt catcaagaag
    22621 gtgcgtcaaa aggatataat cctaagaaac tgggaaaccg atgctacaat atccaatttg
    22681 cattttgcga cgaattaaaa gcatatgtta ccggatttgt aagaagtggc aatacttaca
    22741 ctgcaaacgg tgctgcggaa atgatcaaag aaattgttgc taacatcaaa tcagacgatt
    22801 tagaaatttt atttcgaatg gatagtggct actttgatga aaaaattatc gaaacgatag
    22861 aatctcttgg atgcaaatat ttaattaaag ccaaaagtta ttctacactc acctcacaag
    22921 caacgaattc atcaattgta ttcgttaaag gagaagaagg tagagaaact acagaactgt
    22981 atacaaaatt agttaaatgg gaaaaagaca gaagatttgt cgtatctcgc gtactgaaac
    23041 cagaaaaaga aagagcacaa ttatcacttt tagaaggttc cgaatacgac tactttttct
    23101 ttgtaacaaa tactaccttg ctttctgaaa aagtagttat atactatgaa aagcgtggta
    23161 atgctgaaaa ctatatcaaa gaagccaaat acgacatggc ggtgggtcat ctcttgctaa
    23221 agtcattttg ggcgaatgaa gccgtgtttc aaatgatgat gctttcatat aacctatttt
    23281 tgttgttcaa gtttgattcc ttggactctt cagaatacag acagcaaata aagacctttc
    23341 gtttgaaggg tgatgctgcc aacttactga tttagtgtat gatggtgttt ttgaggtgct
    23401 ccagtggctt ctgtttctat cagctgtccc tcctgttcag ctactgacgg ggtggtgcgt
    23461 aacggcaaaa gcaccgccgg acatcagcgc tatctctgct ctcactgccg taaaacatgg
    23521 caactgcagt tcacttacac cgcttctcaa cccggtacgc accagaaaat cattgatatg
    23581 gccatgaatg gcgttggatg ccgggcaacc gcccgcatta tgggcgttgg cctcaacacg
    23641 attttccgcc atttaaaaaa ctcaggccgc agtcggtaac ctcgcgcata cagccgggca
    23701 gtgacgtcat cgtctgcgcg gaaatggacg aacagtgggg atacgtcggg gctaaatcgc
    23761 gccagcgctg gctgttttac gcgtatgaca ggctccggaa gacggttgtt gcgcacgtat
    23821 tcggtgaacg cactatggcg acactggggc gtcttatgag cctgctgtca ccctttgacg
    23881 tggtgatatg gatgacggat ggctggccgc tgtatgaatc ccgcctgaag ggaaagctgc
    23941 acgtaatcag caagcgatat acgcagcgaa ttgagcggca taacctgaat ctgaggcagc
    24001 acctggcacg gctgggacgg aagtcgctgt cgttctcaaa atcggtggag ctgcatgaca
    24061 aagtcatcgg gcattatctg aacataaaac actatcaata agttggagtc attacctatt
    24121 gacgggtttt atttcaccgc caaacttcac gaaatcaatg aaggcgctat ggcgacgtaa
    24181 tgccgatact ggttgaatgt caaaattagc cagaataaaa aagtaccctg gaaaaatagc
    24241 gaatattctt tcacggtgac agcacctgga gtctgcccgt cttatctttc ttgttattaa
    24301 tggagtccat ggtacgacgt tttgctcatt cagccatgag aataaagatt ctctgttttt
    24361 gccggctgta ttatattgcg caagatacca gttccggtta ttcaggtgtt ctatattcac
    24421 gaagttcaac gctccgcgca aaaccgatcc atgatggacg attttgcgat gtcaggcgaa
    24481 tatgctaaat catatgtctg aagcagtgtc cagcccatat ctggataaac tgcagttctg
    24541 acaggcatat aaccagcaga ctctagtacg ttctgtatcg gtgatttggc gaactcacag
    24601 ataaagaacg gctaagcact aatatcagca atacagtggc acagtatcgt gatacgcgaa
    24661 ataaaacatc agcacgtcag ttcagagtaa ggtcgccata tatcgggcat gagccagata
    24721 caaataattg ggacaccgtc tgaagtgatt tgctttatta aagtaacttg tgcttggtgt
    24781 ttatgtttat caatttggga gcgcctgtaa agtgcaaaat gcaatttcca tgaaagtgtc
    24841 ccctttaatg gggacacctg ttcacatttt ttcgttttct ttagctgtat tgctaatcat
    24901 gaaaacgaac gttcgcatca gcacagcaga gcgaagtgca tcatatcctt ccagatttaa
    24961 gttcttcagg cttcgcttca ggtaggttcg taccgtttcg ggagaaagcc gacagttctg
    25021 agcaatggcg tcgtaaggaa cacccattgc gtaaaaaacg cagactttaa gctggtttgt
    25081 tgatagctcg ggaaacatgc cttccaacag agtgatggcc gggagtttct gtatcatttg
    25141 aggtgacata gcaaaggtct ccgatgacaa caaaaaacgc tatcaccgag ttcctacgct
    25201 cattggtgat agcccagacg ggggtaggaa taccggcgtc atcggaaacc ggccaggcta
    25261 atgcctgccc cgcctgagct accatagatg acgacaagaa atacaagttc ctgtctttat
    25321 ggtatggcaa aaaacgacgc caaatgaaga aattaacttc tgcgccgacg atgactacgc
    25381 gggttcctac gcccgatcac agttttgcct gtgaccagta aagggtactt agtataacgt
    25441 accgagtcaa ctaaccgctt aaaaaacata caaaaaagcg tcaaaactta acgctccgcg
    25501 ccgaagcgat ccaggcatga tgcttctgct ttgtggcgtt cgaacatgct ggtccatatg
    25561 cacgaaacgg tgtctgaccc tcgtccagac aatccgcagt tctgacgaac atatgaacaa
    25621 atatgctctt gtagaggctg ttgttacaca attggcgggc tgtgtaacaa atggttttat
    25681 tatctaagaa tcattctatt tacgatcgaa tgatctacaa aatgattttt taaaggtttt
    25741 ttagatcgtt taattgtctt aaaacagaat attattctgt taggttgatc ggttgtaaga
    25801 taaatgatcg tgagtagaac aaaagtcgat cttttaatcc aaaagaagga tctaaagcag
    25861 aaaaatctgc ttttaaaaat agattttatt tttttgacgc aggtcaagat taactcatta
    25921 gaggtatcgg tgaggaggca ctggaagaga agagatcgtt gtaatgcttt tcaaattaac
    25981 gtaaagcggg tatatttcgg ttgttattag ctgcgcagag ggtggcactc tgtggagcaa
    26041 agcggcgaaa gccggacggc agaatgcgcc ataaggcatt caggagagat ggcatttacg
    26101 ggcagtaagt cagaagaccg aagatgttcc ggaagccata aaaggaaaac ccccacaatc
    26161 tttcgacgaa cttggcggga cggagaaaga ttatgggggc ctcacagaat acgggtaaag
    26221 tataatgaaa ccgtaccaga gattcaaccc tgtgca
//
