LOCUS       NZ_CP075642            42892 bp    DNA     circular CON 27-JUN-2023
DEFINITION  Escherichia coli strain S19-141 plasmid pS19_141-b, complete
            sequence.
ACCESSION   NZ_CP075642
VERSION     NZ_CP075642.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN16993351
            Assembly: GCF_016404325.2
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 42892)
  AUTHORS   Nusch-Inderbinnen,M., Stevens,M.J.A., Cernela,N., Muller,A.,
            Biggel,M. and Stephan,R.
  TITLE     Distribution of virulence factors, antimicrobial resistance genes
            and phylogenetic relatedness among Shiga toxin-producing Escherichia
            coli serogroup O91 from human infections
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 42892)
  AUTHORS   Nusch-Inderbinnen,M., Stevens,M.J.A., Cernela,N., Muller,A.,
            Biggel,M. and Stephan,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-MAY-2021) Institute for Food Safety and Hygiene,
            University of Zurich, Winterthurerstrasse 272, Zurich, Zurich 8057,
            Switzerland
REFERENCE   3  (bases 1 to 42892)
  AUTHORS   Stevens,M.J.A., Stephan,R. and Nusch-Inderbinnen,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-DEC-2020) Institute for Food Safety and Hygiene,
            University of Zurich, Winterthurerstrasse 272, Zurich, Zurich 8057,
            Switzerland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAY-2021
            Assembly Method                   :: unicycler v. 0.4.9b
            Assembly Name                     :: S19-141_NP
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 80.0x
            Sequencing Technology :: Oxford Nanopore MinION; Illumina MiniSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 06/27/2023 06:11:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,151
            CDSs (total)                      :: 5,035
            Genes (coding)                    :: 4,825
            CDSs (with protein)               :: 4,825
            Genes (RNA)                       :: 116
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 210
            CDSs (without protein)            :: 210
            Pseudo Genes (ambiguous residues) :: 0 of 210
            Pseudo Genes (frameshifted)       :: 90 of 210
            Pseudo Genes (incomplete)         :: 109 of 210
            Pseudo Genes (internal stop)      :: 63 of 210
            Pseudo Genes (multiple problems)  :: 49 of 210
            Pseudo Genes (short protein)      :: 5 of 210
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP075642.1.
            Bacteria and source DNA available from Institute Food Hygiene and
            Safety, University Zurich.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..42892
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="S19-141"
                     /isolation_source="stool"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="pS19_141-b"
                     /geo_loc_name="Switzerland: Zurich"
                     /lat_lon="47.40 N 8.55 E"
                     /collection_date="2019"
                     /collected_by="ILS/NENT"
     gene            join(42770..42892,1..756)
                     /gene="repA"
                     /locus_tag="JFX59_RS25165"
                     /old_locus_tag="JFX59_025165"
     CDS             join(42770..42892,1..756)
                     /gene="repA"
                     /locus_tag="JFX59_RS25165"
                     /old_locus_tag="JFX59_025165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019842582.1"
                     /GO_process="GO:0006276 - plasmid maintenance [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="incFII family plasmid replication initiator RepA"
                     /protein_id="WP_047081955.1"
                     /translation="MASLNRLSLHCSEAHYRQVKNPNPVFTPREGAGTLKFCEKLMAKA
                     VGFTSRFDFAVYVAHARSRGLRRRMPPALRRRAIDALLQGMCFHYDPLANRVQCSITTL
                     AIECGLATESDAGKLSITRATRALKFLAELELITYQTEYDPLIGCYIPTDITFTPALFA
                     ALDVSEDAVAAARRSRVVWENRQRKKQGLDTLGMDELIAKAWRFVRERFRSYQTELKSH
                     GMKRARARRDAGRTRQDIVTLVKRQLTREIAEGRFRGSLEAVKREIDRRVKERMIMSRN
                     NNYTRLATASP"
                     /name="repA"
     gene            2105..>2257
                     /locus_tag="JFX59_RS25940"
                     /pseudo=""
     CDS             2105..>2257
                     /locus_tag="JFX59_RS25940"
                     /inference="COORDINATES: protein motif:HMM:NF010277.0"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5431 family protein"
                     /name="DUF5431 family protein"
     gene            2202..2324
                     /locus_tag="JFX59_RS25170"
                     /old_locus_tag="JFX59_025170"
     CDS             2202..2324
                     /locus_tag="JFX59_RS25170"
                     /old_locus_tag="JFX59_025170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004118124.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hok/Gef family protein"
                     /protein_id="WP_223202818.1"
                     /translation="MVCCTLLIFTYLTRNRLCEVRLKDGNREVTASLAYESNGK"
                     /name="Hok/Gef family protein"
     gene            2474..3070
                     /locus_tag="JFX59_RS25175"
                     /old_locus_tag="JFX59_025175"
     CDS             2474..3070
                     /locus_tag="JFX59_RS25175"
                     /old_locus_tag="JFX59_025175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ProQ/FINO family protein"
                     /protein_id="WP_000125165.1"
                     /translation="MTAIIEASMQPKKTPVIVVKKRRVLVMPENPVVNEKPQEVQKSAV
                     NENKKVQKKDAVAEKTRKKQPQPWYLKKQITFPPKYPKEYFEKCFNKVRAVFPELWTDE
                     KKNLPLKSGILQDVEKYLADNPDVDLTIEEWNCAVQVMTFRWQYLQNCTVPGATRYDLY
                     GKPAGTVKKAHATYAQLVLDARKKASEKKQLKRKG"
                     /name="ProQ/FINO family protein"
     gene            complement(3088..3372)
                     /locus_tag="JFX59_RS25180"
                     /old_locus_tag="JFX59_025180"
     CDS             complement(3088..3372)
                     /locus_tag="JFX59_RS25180"
                     /old_locus_tag="JFX59_025180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001542021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001542021.1"
                     /translation="MALDLKTPVIPGQKTEQTNADTARFINEATRKKSGATKVTNVRLG
                     DVYEDILEREALRTGQTKTSIMKAALAAYEHGLDENGKNHWILQSARLK"
                     /name="hypothetical protein"
     gene            complement(3451..4116)
                     /locus_tag="JFX59_RS25185"
                     /old_locus_tag="JFX59_025185"
     CDS             complement(3451..4116)
                     /locus_tag="JFX59_RS25185"
                     /old_locus_tag="JFX59_025185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division plane positioning ATPase MipZ"
                     /protein_id="WP_000532148.1"
                     /translation="MGRALLVASDKGGVGKSTTATNLASYLVNNSRTVIILKTDKNNDI
                     LSWNEKRKQNGLLPVPVYEEYGDVSEVIKRLKKICEVLIIDCPGHDSKEFRSALTVADI
                     LLTLVKPSSDFEAETLTHVTEKVRTAQQINPDLQPWVLFTRINTTKPRHRKAAIDLDKL
                     LRENPVWIQPLRTRISDLDIFEAACNEGAGVHDVRRASSLSTAKAQIELLAQELGINP"
                     /name="division plane positioning ATPase MipZ"
     gene            4620..4949
                     /locus_tag="JFX59_RS25190"
                     /old_locus_tag="JFX59_025190"
     CDS             4620..4949
                     /locus_tag="JFX59_RS25190"
                     /old_locus_tag="JFX59_025190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000855123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_047082006.1"
                     /translation="MKTLTFNNGTVSVGDVFVSSWGYEQTNVNFYQVISVHGKKTVTVQ
                     EIRASVHRTHSMSGYKIPLLNDFCGEPLKRRVRDYFSTPAIEIESFETAYKRSPEEKHE
                     FTSYY"
                     /name="hypothetical protein"
     gene            5119..5415
                     /locus_tag="JFX59_RS25195"
                     /old_locus_tag="JFX59_025195"
     CDS             5119..5415
                     /locus_tag="JFX59_RS25195"
                     /old_locus_tag="JFX59_025195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010846807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_042968292.1"
                     /translation="MIEMKQTPEFEKWLKSLKDKIAKAKILMRLERMEEGNFGDVEPVG
                     DGLSELRIHQGKGYRIYFGNKNNQIVILLCGGDKSTQQLDIKKAKILAKKWGF"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            5417..5701
                     /locus_tag="JFX59_RS25200"
                     /old_locus_tag="JFX59_025200"
     CDS             5417..5701
                     /locus_tag="JFX59_RS25200"
                     /old_locus_tag="JFX59_025200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013583077.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antidote protein"
                     /protein_id="WP_047082007.1"
                     /translation="MNGGLKKFDVVEYLEDEEDIQAYLNAAIEEGDTKYFFKALGNIAR
                     ARNISQLSKDAGMSREGIYKALSGEGNPSFNTVARITKALGLKLQFKGA"
                     /name="addiction module antidote protein"
     gene            5954..6208
                     /locus_tag="JFX59_RS25205"
                     /old_locus_tag="JFX59_025205"
     CDS             5954..6208
                     /locus_tag="JFX59_RS25205"
                     /old_locus_tag="JFX59_025205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_086217910.1"
                     /translation="MRKNKGRLTYYLEISDKKYHFVKKISSYSKEYTEGKTKTTKRTLS
                     ELVFNESEVGAIDFTKNGLRPVDKNILLTMMKECKESDT"
                     /name="hypothetical protein"
     gene            6205..6441
                     /locus_tag="JFX59_RS25210"
                     /old_locus_tag="JFX59_025210"
     CDS             6205..6441
                     /locus_tag="JFX59_RS25210"
                     /old_locus_tag="JFX59_025210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001132407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="WP_047082009.1"
                     /translation="MTIENTPENIKKLRKKIGLTQTECGEIFGVGLSTWQKKEAKTHNQ
                     LNLSKGEFEYLLLLAGEHPDYVLCKRNSDSGNN"
                     /name="transcriptional regulator"
     gene            6453..6599
                     /locus_tag="JFX59_RS25215"
                     /old_locus_tag="JFX59_025215"
     CDS             6453..6599
                     /locus_tag="JFX59_RS25215"
                     /old_locus_tag="JFX59_025215"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_155953439.1"
                     /translation="MKLELTYEEITEQATKTITEFMEQTKSADSRYSADFFITRHGGQK
                     CYG"
                     /name="hypothetical protein"
     gene            7153..7479
                     /locus_tag="JFX59_RS25220"
                     /old_locus_tag="JFX59_025220"
     CDS             7153..7479
                     /locus_tag="JFX59_RS25220"
                     /old_locus_tag="JFX59_025220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020314677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032716095.1"
                     /translation="MENYAKFVATEILNQLGGNRFIAMTGAKNFACFDENGECGLCFRL
                     PSNNFAMKGINLVKIKLTFSDTYLVTFSRVRGATVKEISKFDNVYCDQLEYLFNEQTGL
                     ATRL"
                     /name="hypothetical protein"
     gene            7520..7729
                     /locus_tag="JFX59_RS25225"
                     /old_locus_tag="JFX59_025225"
     CDS             7520..7729
                     /locus_tag="JFX59_RS25225"
                     /old_locus_tag="JFX59_025225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020314678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032716096.1"
                     /translation="MKVLIGNINIDNYHMLSALAGIAGFDRSIKFTCEISASIEIMEDD
                     FVNKAGILKMLDEFIENDFSIKLV"
                     /name="hypothetical protein"
     gene            7827..8051
                     /locus_tag="JFX59_RS25230"
                     /old_locus_tag="JFX59_025230"
     CDS             7827..8051
                     /locus_tag="JFX59_RS25230"
                     /old_locus_tag="JFX59_025230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000814383.1"
                     /translation="MKQSTFPVIVSTTGHVFSVVRVTLCTICLKHEKTGEAYVVIFTDC
                     HNIRDYKKGVVPALGELYQEDVDLITGKS"
                     /name="hypothetical protein"
     gene            8103..8360
                     /locus_tag="JFX59_RS25235"
                     /old_locus_tag="JFX59_025235"
     CDS             8103..8360
                     /locus_tag="JFX59_RS25235"
                     /old_locus_tag="JFX59_025235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001704451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_042968288.1"
                     /translation="MKIRKGDRQYYLNKEGDTFHLVKRVKTFSKSATLGKTKATVKTVA
                     DLVFHEEAFDTIDFASDGLRENDKEIVSMMIQEMSEEKKC"
                     /name="hypothetical protein"
     gene            8354..8605
                     /locus_tag="JFX59_RS25240"
                     /old_locus_tag="JFX59_025240"
     CDS             8354..8605
                     /locus_tag="JFX59_RS25240"
                     /old_locus_tag="JFX59_025240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001132407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin Xre-like helix-turn-helix
                     domain-containing protein"
                     /protein_id="WP_022645142.1"
                     /translation="MLTENTPENIKRLRQKIGLTQKECAEIFSMSPRTWRRKEEPVGTA
                     SGTALTPVEFKFLLLLAGEHPDYVLCKRNKKNSDSGSN"
                     /name="antitoxin Xre-like helix-turn-helix
                     domain-containing protein"
     gene            9143..9448
                     /locus_tag="JFX59_RS25245"
                     /old_locus_tag="JFX59_025245"
     CDS             9143..9448
                     /locus_tag="JFX59_RS25245"
                     /old_locus_tag="JFX59_025245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_072096363.1"
                     /translation="MKCSPVFTSTTNHVFTFERVTLCTIVLIHKDTGQQYVVIFTDNNK
                     IRDYKTGIVSQFGELKQSDIDLILFYRDEYEKYFDSLNNGEEYLSFKEYIGCIRGK"
                     /name="hypothetical protein"
     gene            9754..10041
                     /locus_tag="JFX59_RS25250"
                     /old_locus_tag="JFX59_025250"
     CDS             9754..10041
                     /locus_tag="JFX59_RS25250"
                     /old_locus_tag="JFX59_025250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000606468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000606467.1"
                     /translation="MINEAKKIAVEMMFWTACPVDDDNCFDAIINASKIDREFEDKHAI
                     YLHPIYRDLLSTDQIKSALKKRAIKIISFKCDINEDSARKILMQTILRAV"
                     /name="hypothetical protein"
     gene            10469..10702
                     /locus_tag="JFX59_RS25255"
                     /old_locus_tag="JFX59_025255"
     CDS             10469..10702
                     /locus_tag="JFX59_RS25255"
                     /old_locus_tag="JFX59_025255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000093744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000093744.1"
                     /translation="MSSEVIKQIQKIQDRGIIIYSKFRAAEFDQDDVYRESYFLVVEFN
                     ELIAENIIHDEKLVDQTACILHELRRIAIEGK"
                     /name="hypothetical protein"
     gene            10775..11080
                     /locus_tag="JFX59_RS25260"
                     /old_locus_tag="JFX59_025260"
     CDS             10775..11080
                     /locus_tag="JFX59_RS25260"
                     /old_locus_tag="JFX59_025260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016234217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_047081935.1"
                     /translation="MIDTFDSEKFLSELDVLSKEIMPGCGLVFELYQRRLSAAIDKVVA
                     GLPEEQHAQAFELARQEFDYLSAEEIAEEIRRDSERGYCCHGFDRDCCPLGCGDLP"
                     /name="hypothetical protein"
     gene            11703..11885
                     /locus_tag="JFX59_RS25265"
                     /old_locus_tag="JFX59_025265"
     CDS             11703..11885
                     /locus_tag="JFX59_RS25265"
                     /old_locus_tag="JFX59_025265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833472.1"
                     /GO_function="GO:0003729 - mRNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family toxin"
                     /protein_id="WP_047081936.1"
                     /translation="MKSADLLKELIAAGCELKRHKASSHQIWWSPITGKTFPVPHPKKD
                     LPPGTVRSIKKMAGI"
                     /name="type II toxin-antitoxin system HicA family toxin"
     gene            11910..12347
                     /locus_tag="JFX59_RS25270"
                     /old_locus_tag="JFX59_025270"
     CDS             11910..12347
                     /locus_tag="JFX59_RS25270"
                     /old_locus_tag="JFX59_025270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="WP_047081937.1"
                     /translation="MFFSVGVETPKDDQIAYGITVPAFDRFDFGCVSAADSQAEIPVMA
                     REAILAIVEEMVLSGAHSLDDIHDEGYLAYSDNINYSHCDSWFVIDVDLSEVEGKQQRI
                     NISLPDILIRRIDGYVKESGGVYKDRSHFLAQAARHELTYK"
                     /name="type II toxin-antitoxin system HicB family
                     antitoxin"
     gene            complement(12422..12610)
                     /locus_tag="JFX59_RS25275"
                     /old_locus_tag="JFX59_025275"
     CDS             complement(12422..12610)
                     /locus_tag="JFX59_RS25275"
                     /old_locus_tag="JFX59_025275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5397 family protein"
                     /protein_id="WP_047081938.1"
                     /translation="MNTTQIPTGAVKTFGAFGPPYQVGEEIKELPDGDILVNIILIQTG
                     EKEVYKLSKLLQDPDAK"
                     /name="DUF5397 family protein"
     gene            complement(12864..13535)
                     /locus_tag="JFX59_RS25280"
                     /old_locus_tag="JFX59_025280"
     CDS             complement(12864..13535)
                     /locus_tag="JFX59_RS25280"
                     /old_locus_tag="JFX59_025280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000606418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF47 family protein"
                     /protein_id="WP_047081939.1"
                     /translation="MDKIQDTKAAWQALQEDEVMRKIAIERLVEGFHELEELIKNYPVK
                     IQEQNNIYFENLRNDINNITEAINSLPDAIDEKTSQLQLAAVALHDEFQESKGEVKGSL
                     EEARINATEKLTESAKELQDNITKVAEKTTETIESANKIISTIDTNLAEINKKALANYV
                     NDIRSLEKKGESISKNIDIAINNAFKSSVKSFKFYCGAALFISTVLQFTMWGFFLYKLL
                     T"
                     /name="DUF47 family protein"
     gene            complement(13545..14255)
                     /locus_tag="JFX59_RS25285"
                     /old_locus_tag="JFX59_025285"
     CDS             complement(13545..14255)
                     /locus_tag="JFX59_RS25285"
                     /old_locus_tag="JFX59_025285"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_047081940.1"
                     /translation="MRIAVLNYSGNVGKTTISQHMLLPRLNYEILRIETLNSDGEGNGQ
                     KMAAEDFDKIFNTILNLDDVIIDVGSSNIETFKSKLTFDFAGSHSFIDYFIIPVTPDAK
                     QQIDTIKTIIEFIELGVACEKIKVIFNRVNIKKDIKEQFSTILKSEELKSVCFEITEDT
                     PCISDSTLFKTLERANLTYNNVKDYPTISELDEQLAGKTGKEKIVLELQKFYKLGFNSY
                     QKQMQHAFDALNII"
                     /name="hypothetical protein"
     gene            complement(14262..14852)
                     /locus_tag="JFX59_RS25290"
                     /old_locus_tag="JFX59_025290"
     CDS             complement(14262..14852)
                     /locus_tag="JFX59_RS25290"
                     /old_locus_tag="JFX59_025290"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_052773147.1"
                     /translation="MATIDSLLGPLCDEIKNAKVKSKQILFSMYLHDLLEVKKTHTWQQ
                     ICEYINKHTDSKLSVRTYRNMTERAKKNTTDSVKSPLTKVVERPSSKAGSKVGSSIQKA
                     EERQERDQLGRLIYPKKEFTEEALLEWEDINIPRSSKVLLIRYGVTKDEYRGLQINIMD
                     PSIINDKVREYCKKKESEWDRTHNSHMYRIKQE"
                     /name="hypothetical protein"
     gene            15207..15569
                     /locus_tag="JFX59_RS25295"
                     /old_locus_tag="JFX59_025295"
     CDS             15207..15569
                     /locus_tag="JFX59_RS25295"
                     /old_locus_tag="JFX59_025295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="WP_042968468.1"
                     /translation="MKTKEKKSAENKSIMIGFRLTNEEYSKFASVIEETGVSKSEFFRL
                     VITGKFDPNVHGKVKKDNYRELLRLFNKSSNNINQIAKKINMEYRNGFISENTYLRYLN
                     VLVNIRDSFVTGIEKC"
                     /name="plasmid mobilization relaxosome protein MobC"
     gene            15563..18850
                     /locus_tag="JFX59_RS25300"
                     /old_locus_tag="JFX59_025300"
     CDS             15563..18850
                     /locus_tag="JFX59_RS25300"
                     /old_locus_tag="JFX59_025300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPD7 domain-containing protein"
                     /protein_id="WP_198779954.1"
                     /translation="MLVRINGGNKGVCEYLEKGYKQGREYTRDEIDHRLVLDGDLALTE
                     SVIDTIPDNGQERYIHITLSFFEDNVSESKLHDVVQEYKSLMMNAYHEDEYNFYAEAHL
                     PKIKQMPDYKTGEMVERKPHIHIVIPEVNLVTGSKLNPRGMTEHYIQYLDAIQEHINNK
                     YNLVSPKDGVRVSDHNHANVLSRAKGDFYRERHSEFKSTVFDALDTENIRTEKQFADYL
                     SRFGEVKEYNKGESNRYFGVKLEGDSKFTRLKSPLFSRQYISDRSIPLLKPTKTQIESR
                     LKEWKSSVSHEIKHIHPAGQKIRKEYAALAGEYKQMYLKKVINRYDEKHNLQRQDRRQN
                     SDQSGIKYNTGKFVSGKTIGLPRLPARELVYGLHGRSGGKSINKSQLLLQQNEYGDLST
                     AGRQKVDPDRYVRRLQDRAGRRVVQSPLESNIKAAIQRSDDLPFLKQIRTEINAERYLS
                     NLQTRFNIDPSKHTVTYAQDGSPRFRVGNRNMNASDFLTKHLNLEWDEAKEVLLDIWQD
                     QKDNKPFDAVITRVSLTRQQAKERFICLNEHKGWVNNEIKYKHNDNIANYRAELRGLLA
                     IRNKQEREVARGYIIFKKLEREREINSIRKACFREINSYYHRWNPDRRYDMALGDSLKK
                     IIRNPVDGNSISSGNEKEVFSVVKRVQQSQQVQDYVKRELTDLVPHKVSPKETRYLDPK
                     TTQTVFTDKGNHVRVNGEITQDKAEAALLYAKEKFGGMLKLNGSEEFKVACAMAAAEKG
                     MNVILRPEKYHEMMQVRLQELKAEHGHENSVEAERQQQVAGQKPEQEQEKRAEQVNSVE
                     KDTQAKERTPEVAESVRNDDKSRDAVPEQPVKSEIVSQKSTSETSVVQEAEKQESVQKN
                     VSAHSEEREQQLQEAQQQKPVTEKDVTTGQEKQTGDEQSKSALTTENPQQQNNASLQQL
                     QEEAKVIASQHQEAQRLLNEAVENGAPKEEVDLLSKGVNSISARAQTINEQIKAFEEQQ
                     GQKKAKSVEEKNENTTEKKKRTVNSEKAMEREIERVSKQLAKEMNIDKQTVKDTLKFIR
                     FEDVNDLKAAMKNPETVEAVKREIVSYDNALKDERERERSRDNTRTR"
                     /name="LPD7 domain-containing protein"
     gene            19260..19355
                     /gene="dqlB"
                     /locus_tag="JFX59_RS26100"
     CDS             19260..19355
                     /gene="dqlB"
                     /locus_tag="JFX59_RS26100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinQ-like type I toxin DqlB"
                     /protein_id="WP_042968460.1"
                     /translation="MINLLIIVLRAVVAVANALIAVLELIREFID"
                     /name="dqlB"
     gene            complement(20173..20505)
                     /locus_tag="JFX59_RS25305"
                     /old_locus_tag="JFX59_025305"
     CDS             complement(20173..20505)
                     /locus_tag="JFX59_RS25305"
                     /old_locus_tag="JFX59_025305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001712069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_225394940.1"
                     /translation="MNFIKMTRQVESYRHLGENRIVIRRTKSGGAGCYLTVAVRENKKY
                     VTTEINYESKEIRLKLTDSESEGVRLSFGTFTLPIKFCNDILSKDTKRICLVLEKKNDG
                     WWYCKY"
                     /name="hypothetical protein"
     gene            complement(20575..20769)
                     /locus_tag="JFX59_RS25310"
                     /old_locus_tag="JFX59_025310"
     CDS             complement(20575..20769)
                     /locus_tag="JFX59_RS25310"
                     /old_locus_tag="JFX59_025310"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_042968462.1"
                     /translation="MLKFFIAAISVIFSFLLSGCDNKKADDACIKNKNDVNCISKEQKE
                     KYFKEYLEKTSSQPSSNKE"
                     /name="hypothetical protein"
     gene            complement(20828..21034)
                     /gene="hha"
                     /locus_tag="JFX59_RS25315"
                     /old_locus_tag="JFX59_025315"
     CDS             complement(20828..21034)
                     /gene="hha"
                     /locus_tag="JFX59_RS25315"
                     /old_locus_tag="JFX59_025315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="WP_042968463.1"
                     /translation="MKTKQEWIFQLRKCTSRDTLEKVIDINRYKLPLSESEAFYSAADH
                     RRAELVMNKLYDKVPSGVWKYVH"
                     /name="hha"
     gene            complement(21153..23303)
                     /locus_tag="JFX59_RS25320"
                     /old_locus_tag="JFX59_025320"
     CDS             complement(21153..23303)
                     /locus_tag="JFX59_RS25320"
                     /old_locus_tag="JFX59_025320"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001505316.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="WP_063123057.1"
                     /translation="MKLFIAEKPAVANDIVKALGGNFTRHDGWFESDNAIVTNCFGHII
                     ESQPPENYNPDYKAWKVETLPLRLYPVKYQPVESAAKQVNTILELIRRGDVTEIVHAGD
                     PDEEGQLLVDEVLEYAGNTKPVKRVLINDNTLPAVKKALANLKDNRDFRGLYLKALARS
                     VADAVYGFSMTRAYTIPAQARGYKGTLSVGRVQTPILGLIVNRTRANQNHKSSFYYTMT
                     GVFQRGADVIRANWKPGEFAPLTDRKLLDKAWANGTAASLTGKPATVEAAATDDKKTAA
                     PLPFNLVRLQQYMNKKFKLTAQKTLDITQQLREKYKAITYNRSDCSYLSDEQFSEAPQV
                     IDALKSVFDQPMNVDTTRKSKAFDSAKVTAHTAIIPTANVPDINALTPNERNVYLAIAQ
                     HYLVQFMPEKLYKEVSVAIQCGDESFYARARKTTDSGFEAFLGTETTNEDESDNDDSAF
                     EQLCKIRTGETLTTKEVVVNEKKTTPPPLFTEASLLAALVRVADFVTDPVIKKLLKDKD
                     KDKKDEHGGIGTPATRAAMLEALKKRNYITLEKGKLIPTDTGYALIDALPGIAVNPDMT
                     ALWAEKQTAIENGELTVEEFINELYDELTGMISDVDLGEMKIEAAPAGQSQQLDSPCPS
                     CGKQIVIRPKGYFCTGCEFKIWKNFSGKALSDKQVETLLKKGITGELKGFISSRTNKEF
                     SAKVKLMDKATGKLGFEFIPKK"
                     /name="type IA DNA topoisomerase"
     gene            complement(23308..23883)
                     /locus_tag="JFX59_RS25325"
                     /old_locus_tag="JFX59_025325"
     CDS             complement(23308..23883)
                     /locus_tag="JFX59_RS25325"
                     /old_locus_tag="JFX59_025325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_063106887.1"
                     /translation="MQYALFDGFERKFLLDALEFGVLKDWKENPVKELPDIDESVHPFH
                     VCYGGYLLNPGVSDSDISRKIKDQTGFWLAAIDDTRMDCHSIAYYDIHTLPLISCGRQK
                     IVPFAALIKADECIISKIASYSGFAVTAFLRIKDQDIATNILNREGIFAFNGCERRFRQ
                     PVGEDNWKQAISEERAIRCANRLIQCKG"
                     /name="hypothetical protein"
     gene            complement(23894..24202)
                     /locus_tag="JFX59_RS25330"
                     /old_locus_tag="JFX59_025330"
     CDS             complement(23894..24202)
                     /locus_tag="JFX59_RS25330"
                     /old_locus_tag="JFX59_025330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001371837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_231286801.1"
                     /translation="MSRVIDYKTAEMSVDIPPFPEWNSGHYIEIPGEGIVFTGEKSDDG
                     SRCYSGVIESHYSTDDWPFILSEYKNWLKDKERKFSYLFVLRNGELVHHEVNKSELL"
                     /name="hypothetical protein"
     gene            complement(24244..24996)
                     /locus_tag="JFX59_RS25335"
                     /old_locus_tag="JFX59_025335"
     CDS             complement(24244..24996)
                     /locus_tag="JFX59_RS25335"
                     /old_locus_tag="JFX59_025335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001565871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_042968472.1"
                     /translation="MMTKNDKERFNKRISGEVQISADIPVSDLMTEGAAYVTITESSLY
                     ERVCQYALQHGEDLQGMFKDEKYEYMSCFVRDVAAFRSNFESEELLKPLFNHDKGDTVE
                     FVISVPEKRVEDYGDIVRKEFVDIIQQHVITINNKLWKKFVKQAMTGTTLYIGFDINTG
                     AMVDPEDERDTILKSSRQEFVRTTTFDSFQPDYYVERLYSGAKEIGNINGFNVWFNERG
                     FYFYWNEETEFLIESWLTFPAYPYGWFK"
                     /name="hypothetical protein"
     gene            complement(25396..25779)
                     /locus_tag="JFX59_RS25340"
                     /old_locus_tag="JFX59_025340"
     CDS             complement(25396..25779)
                     /locus_tag="JFX59_RS25340"
                     /old_locus_tag="JFX59_025340"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_198779955.1"
                     /translation="MDYDDSGINNKQGDMMTFIKITRQREFMERSNSARLVLRKEKRRN
                     GIVNCYLSKKARGDDIFIIIELNPEHKKIRLKTTNSTEGHKMSRGGFSLGKVFEEIFHK
                     YFHNDRIVIALKKRDDGWWYGSY"
                     /name="hypothetical protein"
     gene            complement(25786..26253)
                     /locus_tag="JFX59_RS25345"
                     /old_locus_tag="JFX59_025345"
     CDS             complement(25786..26253)
                     /locus_tag="JFX59_RS25345"
                     /old_locus_tag="JFX59_025345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001589395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_042968473.1"
                     /translation="MNKSDAEKIDLILDEHEKTFKKHNHLYILLGNGFFITCILCMIIT
                     FCVSGTYLKYLCLFLVSSCAVCGYIFYYYALLPRSRMVLNRKEVLRLIRLTEDIPDARQ
                     ELLNRLLSGKKLTGRDEEDIRRLWQEKMDAINKSVTRQSEQETIQKFVERG"
                     /name="hypothetical protein"
     gene            complement(26644..26973)
                     /locus_tag="JFX59_RS25945"
     CDS             complement(26644..26973)
                     /locus_tag="JFX59_RS25945"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_225304138.1"
                     /translation="MKPRLLISVTLLSALTFILPASAKIKGLSAAGDPCEVLVCMAEKV
                     QGAPQPGCIAVNQRFFNIRVYTPFYNPGATYGARQNFLYTCSGTAVNQPTLNMIMQRYG
                     SAFSG"
                     /name="hypothetical protein"
     gene            complement(27221..29260)
                     /locus_tag="JFX59_RS25355"
                     /old_locus_tag="JFX59_025355"
     CDS             complement(27221..29260)
                     /locus_tag="JFX59_RS25355"
                     /old_locus_tag="JFX59_025355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727494.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA transfer
                     family protein"
                     /protein_id="WP_198779956.1"
                     /translation="MKKKKLVLPVLIVWLMALTASGWLGSFILVKIASLPTDNLQWSTY
                     LSTLAYYGWQPSLKKYLFAGLAGTLLPFLIALILTVVMFVAVREKKTVHGNARLANDRD
                     LADSGFFPDEKELKNQKYPSLLIGKMPENKGRFKSRYLQYSGQQFLMLYAPTRSGKGVS
                     IVMPNGIWYTESMVFLDIKLENFLETAGYRKNVLKQEVYLFSPDGYAREIGGETVLTTH
                     RYNPLYYIRRDPVYRFGDLEKIAVILFPMTGGENDTWVESSKNVFISLVLWLLDTELEG
                     KFKVNMNSVMKLSIPTDGSSLAKWMLNEIRSRGNEVLTERWKAYHALPEEEKQGKAPST
                     YPLSDDTIRLFRQFAAKDPEQQESIMLDFNRTMSMFANPVVAAATEDNDFDMRDVRRKK
                     MTIYYGISPGALKQYQRLTNLFFSQLLNENVRTLPEHDATLKYQCTLMLDEFTSIGRLD
                     VVQVSLAFTAGYNLRFVFILQNREQLFDEKLGYGKMGGNTILKNCAVEIFYPPKKVDDS
                     VKDVSETIGYYDFVRTQISRTTGKNPSTTRNKVIEKRAVMLPQEIIDLRDQKFKVKGEK
                     TKFSLPQIVMSEFCRPFISHKIVSFDQKNESFFVNARKYSRKNIIDTPVLDIPQDEVVR
                     QLMLQREREEAWKATQPAFDKDDFDDDKEYFPDDDGGDGGGGGD"
                     /name="type IV secretory system conjugative DNA transfer
                     family protein"
     gene            complement(29580..30593)
                     /gene="virB11"
                     /locus_tag="JFX59_RS25360"
                     /old_locus_tag="JFX59_025360"
     CDS             complement(29580..30593)
                     /gene="virB11"
                     /locus_tag="JFX59_RS25360"
                     /old_locus_tag="JFX59_025360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016234221.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_042968733.1"
                     /translation="METINMFLESTGVQPFLEAEGLTEIIVNRPFEIITEGVNGWEYHE
                     APGASYSDLLDLSIAINKYNNSAEPLDTLHPIKSLVMPGGERMQIIMPPACEERCISFT
                     IRKPSLRRFTLEDYVNSNRFSNVRIVNQANLSALSASQQTLLDLLDNTRCAPRTWISFL
                     EAAVAARMNILVVGGTGSGKTTIAKTIADLFPRDRRIITIEDVHEMTLPNHRNHVHLFY
                     KQGGVQPRYLIEAAMRMKPDHIFLAELRGDEAWSYLEVLNTGHEGSVTTIHANSALDAI
                     SRLASIVKQSTVGLTLDHSFILKTIKTSIDIVVFFKHTHMTEIYYNPMEKNQLLAA"
                     /name="virB11"
     gene            complement(30593..31816)
                     /locus_tag="JFX59_RS25365"
                     /old_locus_tag="JFX59_025365"
     CDS             complement(30593..31816)
                     /locus_tag="JFX59_RS25365"
                     /old_locus_tag="JFX59_025365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbI/VirB10 family protein"
                     /protein_id="WP_000794677.1"
                     /translation="MKNNNDIVIEKLDEIDTQEADTDAQNRNFIHSGKKQGNKKAKAVL
                     ILAGFAFVTVVILTSVLSKVFSSSGEEETTETATTKAQAEVYAQNTQAKNLDDLKESVA
                     RSIEEVKNNVNSEEEQAREEAPPENKENKGVTLPAENEADTGYTQNNGDAPPTPEQRRL
                     MGSVMVDDSRITQSQPGSSGQKTAGATPASDNTNVSGDGDFLQGADFADGSVSRIKNRR
                     FLLSAGTTFPCVLKTMIVTTYPGVTLCQLTKDVISDDGKTVLIRAGAQLQGEQTKAITQ
                     GMARVFVNWTMVKDRNVRVRINALGADSLGASGLPAWVDTHFWERFGGALMLSLIEDTL
                     AAGTSRLSRENNSDFTMNNTTGTSSELAKTTLDNSINIPPTGYVNQGEMLTVIVPRNID
                     FSSVYGVR"
                     /name="TrbI/VirB10 family protein"
     gene            complement(31806..32603)
                     /locus_tag="JFX59_RS25370"
                     /old_locus_tag="JFX59_025370"
     CDS             complement(31806..32603)
                     /locus_tag="JFX59_RS25370"
                     /old_locus_tag="JFX59_025370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000980279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbG/VirB9 family P-type conjugative transfer
                     protein"
                     /protein_id="WP_198779948.1"
                     /translation="MMMRKLLLSLVISGITMTCHAAKTPASAGFDRRVQQIVYNPNDVT
                     IVKTKAGEVTLIELEEGEIIKSEDTGLAIGDPEAWDPAVRGNTIFLRPKAAEPDTNIAI
                     VTNKRIYSIQLVSTDQNPTYLLRYIYPKPPEPVKPNVMTGRSRVVAPCTEGNVINGRYE
                     VRGGRKIKPEAIWDNGRLTCFRWPGAADLPVVFRILPDGKEQLVNYHMDKNIMVVHEIS
                     PAFVLRLGGEVMEVRTNRHIPRTWNDSGTLTGETRVEINNDEK"
                     /name="TrbG/VirB9 family P-type conjugative transfer
                     protein"
     gene            complement(32600..33346)
                     /locus_tag="JFX59_RS25375"
                     /old_locus_tag="JFX59_025375"
     CDS             complement(32600..33346)
                     /locus_tag="JFX59_RS25375"
                     /old_locus_tag="JFX59_025375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_047081948.1"
                     /translation="MGLKEYFKKSKAEARKTPAQKEIDKKIEKNVLDAAKEFARDRDNE
                     LKRSLRITRFALFFSSASAAAMAVALAVMAPLKTTEPFLLRVDKTTGYTDVITPFSQDS
                     GTYDEAISRYFLTRYLENREGYDWYTIQNMLNTVELMSSSPVFAEYNNMIHGPLSPLYK
                     LKKSYKILVRVQSITFLDENTAQGRLVKAITDPDGKPAPGYTPTQWIATIKFVWAKDKI
                     TTEAERQINPFGLDVLSYRIDPEVVK"
                     /name="type IV secretion system protein"
     gene            complement(33547..34596)
                     /locus_tag="JFX59_RS25380"
                     /old_locus_tag="JFX59_025380"
     CDS             complement(33547..34596)
                     /locus_tag="JFX59_RS25380"
                     /old_locus_tag="JFX59_025380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_225276418.1"
                     /translation="MMASNDAAFTKANFEIVQPMFNELSSIIQNSVTTNFQTIMQLVSP
                     LFGAAVILYGVFFAWEIMYTRKDDVMMESVKRMGVLTLVFAMTTAGGMYLSYIVPFVQG
                     SGQEVASRIIGQDGASTGAVIDGLLNRLIDLGIQQFNEFQKAKGWFDSMGAWAIFILKA
                     ITLTLAGGGFVIYCAAYLLMAEMMVGILLSIGGVFIFFSAWPTTRNMFTAWVGSCFNYI
                     FLNIAYACLFKVLIQYINNYININSDAIAKNIWSVLCIALVFLIGKFLLAQISALISTL
                     TGGVGINGLTSATGDAIKALRGIGNNTRNQLGLGFNKTATDARERNREYAAAAKDYLSS
                     RFNGNIKAG"
                     /name="type IV secretion system protein"
     gene            complement(34659..35024)
                     /locus_tag="JFX59_RS25385"
                     /old_locus_tag="JFX59_025385"
     CDS             complement(34659..35024)
                     /locus_tag="JFX59_RS25385"
                     /old_locus_tag="JFX59_025385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_042968730.1"
                     /translation="MFKKLLGGFILAFAFLLSGCDGDNGELAGTYIEKNPDSGDAPEKW
                     IIKYDKKDNYYTQIWVEKDKKGNERNGTTNSFLIRDGDWLGDKEDGQGREKHFIRVIDK
                     NTLQFRDDENDLYIRVN"
                     /name="hypothetical protein"
     gene            complement(35118..35786)
                     /locus_tag="JFX59_RS25390"
                     /old_locus_tag="JFX59_025390"
     CDS             complement(35118..35786)
                     /locus_tag="JFX59_RS25390"
                     /old_locus_tag="JFX59_025390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_042968729.1"
                     /translation="MKKTLTALLVGVALAGYSSVASSVGGVIVKDPGSIAKTVEVIKKA
                     SDQIAELKKQVDLATSQLEAYKQEVLDTKRRLEGITDYSAIFGSAESYMKDFWNDMKKE
                     LTDADIRSMATKYGFDTKEYDRIKRQYESKFEEITKYEAMSKDLEKSAEKIKATQKAFS
                     KADTPQKREELQNNILLETAAMQLKIAQNEAEINRMARERKLREEAELIKYTESNFSLN
                     "
                     /name="type IV secretion system protein"
     gene            complement(36472..38907)
                     /locus_tag="JFX59_RS25395"
                     /old_locus_tag="JFX59_025395"
     CDS             complement(36472..38907)
                     /locus_tag="JFX59_RS25395"
                     /old_locus_tag="JFX59_025395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016234213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein VirB4"
                     /protein_id="WP_198779947.1"
                     /translation="MSIKKITNNFIPPYHSHIHENIIWLEDKKLLLTFLIEGIPYESLT
                     DDMILNNFNGQKETLLGLCKSEKVFLWEHLVKRDSPMDARYKFPDNPFLQRLSDFYCET
                     FNGERSLRTEYFITTGIPYDDIDAGEKKAKDIIRQIETGFKDYNIYTLGISEGCISDIC
                     TNYLNYLLNHDFEKIPLSATKISESIKNSKFYFSFDTLEIKNRNGHDNKFCSNYIVKDV
                     PRGSQIGQWNFLLSLPFEFILTQSFIPDSLSKSSKKIEQQLNKLTSVKDAGKTQQTELH
                     MAQEAIINQETVFGSWHSVLSVFGNTPDEASNNGSEVAAEFVTSGRGFRFVRATSEAPY
                     AWFSHLPASTLRPLATQRTLSNVCCLMPLHNHSYGKKSGNPIGDGSAIMPLKTVTDGLY
                     WFNTHYSAPGRNVTGQMIAGHAMLLGATGAGKTTFEMMAAAFLQRFNPDMFVIDFNRST
                     ELAIRMFGGQYFSLAEGVYSGLNPFQIGDNDDPELMAFLKEWVKRCAVNNDGSDCSDSE
                     AEEIDRAVEMVMKLERRQRRFARLQSRIQNPDLNLRLSKWWDNGALSWATDSEENKFDP
                     DKYSKIGFDTTVILETVNERDHPACEVILSVLFFYKKRMQKGGKLMLSIVEEFWKPCNY
                     PMTQALIKASLKAGRMKGEMMWLTSQSPEDAINCQIFAALVQQTPTKILLPNPDAKYSG
                     YKEIGLTEKEFRQLKKLKLESRTMLIKQSGSSAFAKMDLVGFDDFLPVISCSMKGIKLC
                     EKIREEIGSDDPELWYPPFIEGIYQIEDVIREANSDIPEVWLPFMMKRLKDKLPEKSL"
                     /name="type IV secretion system protein VirB4"
     gene            complement(38909..39232)
                     /locus_tag="JFX59_RS25400"
                     /old_locus_tag="JFX59_025400"
     CDS             complement(38909..39232)
                     /locus_tag="JFX59_RS25400"
                     /old_locus_tag="JFX59_025400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB3 family type IV secretion system protein"
                     /protein_id="WP_063123066.1"
                     /translation="MDKEEIKAAEELKAVYLTYNGLNRPAMIKGMPIIPFILCLLALMV
                     SFFIGILTIGFYGLIIPSVIIGVMIAIKQMCADDPNAMSARALKFKGQCLKGFRSNNVL
                     KVE"
                     /name="VirB3 family type IV secretion system protein"
     gene            complement(39288..39593)
                     /locus_tag="JFX59_RS25405"
                     /old_locus_tag="JFX59_025405"
     CDS             complement(39288..39593)
                     /locus_tag="JFX59_RS25405"
                     /old_locus_tag="JFX59_025405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016234214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_042968726.1"
                     /translation="MHKSINLYRTFFLFVCAFFIASNPALAAGVGGLDKGTTFIGELRL
                     WAYGFVGGVALLHILWKVFQAYTEMDSWAGVLKSLMYAAIAGGCVVAAEACYQIFK"
                     /name="hypothetical protein"
     gene            complement(39672..40253)
                     /locus_tag="JFX59_RS25410"
                     /old_locus_tag="JFX59_025410"
     CDS             complement(39672..40253)
                     /locus_tag="JFX59_RS25410"
                     /old_locus_tag="JFX59_025410"
                     /inference="COORDINATES: protein motif:HMM:NF013618.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_077775181.1"
                     /translation="MTLISQCAPGVSPETMRAIIMTESGGNPYAIANVTDGGSKYFTTE
                     EEAVHHAKKLTANKKNFSAGLGQINSRNFQALNLTHESVFSPCTNIRAAAAVLKTCWDK
                     YEKKGGEQQKILRDTMSCYYSGNNKRGYVKESNGKSYIDIIEEKAGLHTHYDIPAIKSY
                     SEKPRPFMVTNDSHDKWDVFGDFKTHDFKE"
                     /name="lytic transglycosylase domain-containing protein"
     gene            complement(41339..41623)
                     /locus_tag="JFX59_RS25415"
                     /old_locus_tag="JFX59_025415"
     CDS             complement(41339..41623)
                     /locus_tag="JFX59_RS25415"
                     /old_locus_tag="JFX59_025415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001330654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_042968722.1"
                     /translation="MSQAKANLKKLRYARYIPPKQKISRLYYVEKALCSPWIYRDQPAE
                     KTELQLTHDTLLVIYGLAKSGLINRSEESLNSEITGVRKALAAGRFRWS"
                     /name="hypothetical protein"
     gene            complement(41643..41876)
                     /locus_tag="JFX59_RS25420"
                     /old_locus_tag="JFX59_025420"
     CDS             complement(41643..41876)
                     /locus_tag="JFX59_RS25420"
                     /old_locus_tag="JFX59_025420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001371659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_042968721.1"
                     /translation="MRDNYHDGLIAGFVVAFSFAGLILLIASILINTEKKHSDTEFYEW
                     AVSHCEKVENNLNVTEESKTFKCEDGKIYIIK"
                     /name="hypothetical protein"
     Typing          2..756
                     /name="IncFIA"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.651"
                     /coverage="88.0"
                     /evalue="0.0"
     Typing          15564..18802
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="96.944"
                     /coverage="99.0"
                     /evalue="0.0"
ORIGIN
        1 atggcaaagg ctgtgggctt cacttcccgt tttgattttg ccgtttatgt ggcgcatgcc
       61 cgttcgcggg ggttgcggcg acgcatgccc ccggcgctgc gtcgccgggc tatagatgcg
      121 ctgttacagg gcatgtgttt ccactatgac ccgctggcca accgagtcca gtgctccatc
      181 accactctgg ctattgagtg cggactggcg acggaatctg atgccggaaa actatctatt
      241 acccgtgcta ctcgcgccct gaagttccta gccgaattgg agctgattac gtatcagacg
      301 gaatatgacc cgcttatcgg gtgctacatt ccgaccgata tcacgttcac accggcgctg
      361 tttgccgccc ttgatgtgtc tgaggatgca gtggcagctg cgcgccgcag ccgtgtggta
      421 tgggaaaaca gacagcgcaa aaagcagggg ctggataccc tgggtatgga tgagctgata
      481 gcgaaagcct ggcgttttgt ccgtgagcgt ttccgcagtt accagacaga gcttaagtcc
      541 cacggcatga aacgtgcccg tgcgcgccgc gatgcaggca gaacccgcca ggacattgtc
      601 accctggtga aacggcagct gacgcgtgaa atcgcggaag ggcgtttccg gggaagcctg
      661 gaggccgtga agcgcgaaat cgaccgtcgt gtgaaggaac gcatgataat gtcgcggaac
      721 aacaactaca cacggctggc cactgcctca ccctgaattt gacctcatct gaataatccg
      781 gcctgcgccg gaggcttccg cacgtttgaa gcccggtgac gcacaaaaaa gcagcgctga
      841 acacaaaaaa cagcctgatc atctaccttc cggctcgtca tgttcccctt gtttttcacg
      901 caaaacacgc ctcacggaca gggaattctg cttatcaaca tttaactgca agggacttct
      961 ccataaagtt acaaccgttc atatcataaa gtgccagccg taggcgttac agggtgcaat
     1021 gtttctttta aaccccagta ctgtatttcc tttaaactac ttaattactt ccatttaaaa
     1081 aaaaacctat tcagtgcctg tcctgtggac agacaaatat gcacctccca ccgcttcgcg
     1141 gcgggcatat ggacttctgc ctaatgaaaa acaaagcccc tccaaccctc ctacaaaaaa
     1201 acgctgcaaa tactcagcca cagcgcccaa cccatcactg aaaagcgccg ccgcccccgc
     1261 ccaaagggcg ggaacaacat cgctttcaat aatggatgtt gtaactaaga aatcacatgg
     1321 ctgtcagtct tctggctgga agtaccgagt acacgctcgt aagcggccct gacggcccgc
     1381 taacgcggag atacgccccg actgcgggta aacccttgtc gggaccactc cgaccgcgca
     1441 caaaagctat ttcatagctg aaagcgggta tggcttagca ggatggagat gggtaaggtg
     1501 aaacctatca atcagtaccg gcttacgccg ggcttcggcg gttttactcc agtatcatat
     1561 gtaacaacgg agtgccgcct tccatgccgc tggcgcggca tcaaaaaaga aagcccccca
     1621 atgacggggg gaaatagcgt tttgatcaaa ataataatgc tagtgtgctt cttgcgtgcc
     1681 attccaggca caaactaaat ttaacgtttc gttaactaca aagaaatccg atgagttaat
     1741 cacttgcgaa ataaaaatca tatagtaaat tactatatga ttttgcgttg tttcggagaa
     1801 ttaaaaaatg cctttgattg aatacatcaa caagttctat cgggggaatc aggcatcgtt
     1861 cgccaggctg accggagttc aacctgcgca ggtaacacag tggatcaaca aaggattcat
     1921 cgtggtgaat cacacactgt atagtccacg ccgaaagctg ggaatttaat tcctggtcaa
     1981 tatataatgc tgttggcgct tgaggctttc tgcctcatgg cgaaaaggtg gtttgtatct
     2041 tgttgtgcgg cagaaagaag aaagccccgt agttaatttt tcattaaccc acgaggcgat
     2101 cccaatgctt gaacaacatc aggatagcct cttaccgcgc gttacgcaag gagaagaagg
     2161 ccatgaaaca gccgaaaaac gccctgacct ggtgtttatt aatcgtgtgc tgcacattgt
     2221 taatattcac gtatctgacc cggaatcgtt tgtgcgaggt ccggctgaaa gacggaaaca
     2281 gggaggttac ggcaagtctg gcttacgaat ccaacggtaa gtagcaaccc ggaggcgggc
     2341 gaaagcccgc ctttttgggg gggatgtggt tctggcatta agcgccttta caaagggggt
     2401 attctgtacg gataccccct ttttccatgt attttcagga tattaactgc tgaaaatggt
     2461 ataattagtc aatatgacag caattattga ggcgagtatg cagccaaaaa aaacacccgt
     2521 gattgtggtc aaaaaacgcc gcgttctggt catgccagaa aatcctgtgg tgaatgaaaa
     2581 gccgcaggaa gtacaaaaat cagcagttaa tgaaaacaag aaagtacaga agaaagatgc
     2641 tgtagcagag aaaacacgta aaaagcagcc tcagccctgg tatttgaaaa aacaaatcac
     2701 ttttccccca aaatatccga aagaatattt tgaaaagtgt ttcaataaag ttcgtgctgt
     2761 ttttcctgaa ctatggacag acgaaaaaaa gaacttgccc ctgaaaagcg ggattctcca
     2821 ggacgttgag aaatacctgg cggataaccc ggatgtggat ctgacgattg aagagtggaa
     2881 ttgtgcggtt caggtgatga cgttccggtg gcaatatctt cagaattgta ctgtaccagg
     2941 cgcaacacgt tacgaccttt acgggaaacc tgctggtaca gtaaaaaaag cacacgcaac
     3001 ttatgcgcaa ctggttctcg atgcccgtaa gaaagccagc gagaagaaac aattaaaacg
     3061 taagggataa agccccgaag ggctttatca tttcagcctg gctgactgta gaatccagtg
     3121 attttttccg ttctcgtcca ggccgtgttc gtaagctgca agagccgctt tcattattga
     3181 tgtttttgtc tggcctgttc gcagtgcttc ccgttccaga atatcttcgt aaacatcccc
     3241 aagccggaca ttggtcactt tagttgctcc cgattttttg cgggtagctt cattgatgaa
     3301 tcgggctgtg tcagcattgg tttgttctgt tttttgtcct ggtattaccg gagttttcaa
     3361 gtcaagagcc attatatcac ctttcgcgtg ttacattaac cttacattgt aaagctaatg
     3421 atgtaaagct atcgtattac atccattaac tcagggattg atgcctaact cttgcgccaa
     3481 aagctctatt tgtgctttag ctgtagaaag gctggatgcg cgacgtacat catgaacgcc
     3541 agcgccttca ttacaggccg cttcaaaaat atctaaatct gaaatacgtg tacgaagtgg
     3601 ctgtatccac accgggttct cccggagtaa cttgtcgaga tcaatcgctg cttttctgtg
     3661 gcgtggtttt gtcgtgttaa ttctcgtgaa aagtacccag ggttgcaggt ctggattgat
     3721 ctgttgagct gtgcgaactt tttctgttac atgagtcagc gtttctgctt cgaaatctga
     3781 agacggctta acgagagtaa gcagaatgtc agctacagtt agggcactgc gaaattcctt
     3841 gctgtcatgc cctggacagt caatgatcag cacttcacat atttttttca ggcgcttaat
     3901 gacttctgat acatcgccat actcttcata aacaggaacc ggtaataagc cattctgctt
     3961 tcttttttcg ttccagctaa gaatatcatt gtttttatcg gtcttcagaa tgatgaccgt
     4021 tcgtgaatta tttaccagat aagaggccag gtttgttgct gtggtgcttt ttcctacacc
     4081 gcctttatct gatgcgacaa gtaatgctct tcccatagaa acctcggata tacagtgtaa
     4141 aggtttattt gtctttacat tgtattcatc atgattacgt tgtaaagatg tttgtgtctt
     4201 tacgttgtaa ttatcgtttg tgctttacat tgtatgtatg ttacagggta acttttaagg
     4261 atgtgatttc gcctggtgtg ttgttgcgcc cgtagctcgc tgaggctcac acgcgcagta
     4321 cagcgtcatc gttgtctgtg agtcagtcgg gcttagcagg gcgggaaggt ggacctggtt
     4381 ccggttgata acagtagcgg ctgcgccgcg cttcggggcg atgtggctcc tgtgcttccc
     4441 tggtattttc gttcgcccct tacatccgct tgcgcggata aaaagcgtga caatcatcaa
     4501 ataatttacc gtttttctgg gcggaagcct tgcctataca tctaaataga tgtattattg
     4561 tttcatcgaa aggagatagg cttctttcct tcttaagtcc aaacggacag gagataaaaa
     4621 tgaaaacatt gacttttaat aacggcactg tttctgttgg tgatgtgttt gtatcttcct
     4681 ggggatatga gcaaacgaac gttaatttct accaggttat ttctgttcat ggcaaaaaaa
     4741 ccgtaactgt tcaggagatt cgcgcttcag ttcatcggac tcattcaatg agcggatata
     4801 agatcccatt acttaatgat ttctgtggtg agccattaaa gcggcgtgtg cgtgattatt
     4861 tcagtacacc agcaatagag attgagtcat tcgaaacagc atataaaaga tcaccggaag
     4921 aaaaacacga gttcacatca tactactaag aaaatagttg cagggggaag cccctgcaac
     4981 cttgttaaaa atgtttatag tggaagtatt tatccggtgt gttcagtact ttcggttagt
     5041 gaggataaat acaatgtgtt aactgtggtt gacacttctg ttatgtggag tatacttaaa
     5101 ctatcaggga ggggctttat gatagaaatg aaacagacac cagagtttga aaaatggtta
     5161 aagtctctaa aagacaaaat agcaaaagct aaaatattga tgcgcctcga acgcatggag
     5221 gaaggaaact tcggtgatgt tgaacctgta ggagatggat tatcagaatt aaggattcat
     5281 caggggaaag gctaccggat atattttgga aataaaaata atcagattgt tattttactg
     5341 tgtggtggtg ataaaagcac acaacagttg gatattaaga aggcaaaaat tttagcgaaa
     5401 aaatggggat tttagtatga atggtgggct aaaaaaattt gatgttgttg agtatctgga
     5461 agatgaagaa gatattcagg cgtatctgaa tgcagccatt gaagagggag atactaaata
     5521 tttctttaaa gcacttggaa acatagccag agcaagaaat atcagccagc tatctaaaga
     5581 tgcaggaatg tcgagagaag ggatatataa ggcgttatcc ggtgaaggta atccgtcatt
     5641 caacacggtt gccagaataa ctaaggcact tggcctgaaa cttcaattca aaggggcctg
     5701 attgcccctt tttatccgat gcgccattta ataattattt tgtgtgtatg aatacacatc
     5761 ttatatggcc gattctggtg tgttgtcccc gtagctcgct ggcgcttgcg ctaactgcgg
     5821 cattctgcgg cgcaaatcag catcatcgtg gtctgtgagt cagtcgggct tagcagggcg
     5881 accgttatga tttgcagatt cggggcttga atatagatca acttgttaaa attacaggat
     5941 atttgaaaca gttatgagaa aaaacaaagg acgattgact tattatcttg aaataagtga
     6001 taaaaaatat cattttgtaa aaaaaataag cagctattca aaggagtata cagaaggaaa
     6061 aactaaaaca acaaagagaa cgttaagtga actggttttt aatgaaagcg aggttggggc
     6121 aatagatttt acaaaaaatg gtttaagacc tgttgataag aatattctct taactatgat
     6181 gaaagaatgt aaggagagtg atacatgacc attgaaaata caccggaaaa cataaagaaa
     6241 ttacgtaaaa aaataggtct tactcagaca gagtgcggtg aaatttttgg tgtaggttta
     6301 agtacatggc agaaaaagga agcaaaaacc cacaaccagt taaatttgtc caaaggtgaa
     6361 tttgagtacc tgttattgct tgcaggggaa caccctgatt atgtgctttg taaaaggaat
     6421 tctgattctg gaaataatta aggaacatta aaatgaaact agaattaacg tatgaagaaa
     6481 tcacagaaca agctacaaaa acaataactg aatttatgga gcagactaaa tcagccgata
     6541 gcaggtattc cgctgatttt tttatcacgc ggcatggggg gcaaaaatgt tatggctgaa
     6601 cttaatagcc ccagtaaaga atgattccag ttgtaaacta gattgctttc tagccattaa
     6661 aaagcaaagt gaaatatttg agcaactggt agacagagaa tcagtgcctg cactgaataa
     6721 tgagcaattg cgcccgtagt tcgctgacgc tcacacgcgc agtacagcgc cccgtccagg
     6781 gaaaccctgg acggcgtaaa ctcgctggcg cgagcgctaa ctgcggcatt ctgcggcgca
     6841 aatcagcgtc atcgttgtct gtgagtcagt cgggcctggc agggcgggaa ggtggacctg
     6901 gttccggttg ataacagtag cggcgtagcc gcgcttcggg gcgatgtggc cccgctgctc
     6961 cctggtattt tctttcgccc cttctatgcc ctgccgggca ttgcatgaat gtaaatattt
     7021 gtatttaacg atatttattt taaagaaagg aggaaaaaat acttgataat aggtcagttc
     7081 tgacctatta taaacacatc gagaggggat ggtccccaat caccaaagcc gctcagcggc
     7141 aggagcttaa aaatggaaaa ctacgccaaa tttgttgcta ctgaaattct taatcaactt
     7201 ggtggaaacc gctttattgc tatgacaggc gcaaagaact ttgcctgttt tgatgaaaat
     7261 ggtgagtgtg gtctttgctt tcgtttgcct tcaaataatt ttgcaatgaa gggaattaat
     7321 ttggttaaaa tcaaattaac cttctctgat acatacctgg tgacattttc ccgtgtccgt
     7381 ggagctacag taaaagaaat atcaaaattt gataatgttt attgtgatca gcttgaatat
     7441 ttgtttaatg aacaaaccgg acttgcaacc agattgtaat ttttaatatg gggggattcc
     7501 ccccatatca ggaggataaa tgaaagttct tattggtaat ataaatattg ataattatca
     7561 tatgctgtct gcattagctg ggattgcggg atttgacagg agcattaagt ttacatgtga
     7621 aatatcagca agtatcgaaa ttatggagga tgatttcgta aataaagctg gtatattaaa
     7681 gatgttagat gaatttattg aaaatgattt ttcaataaag ctcgtctaga aaatacttga
     7741 taataggtca tttgtgacct attattaata cattgagagg ggatggtccc caatcgccaa
     7801 agccgctcag cggcaggaga ttaaatatga aacaatctac ttttcctgtt atcgtctcta
     7861 caactggtca tgtgttttct gttgtgcgcg tgacgctttg caccatttgc cttaaacatg
     7921 aaaaaacagg cgaggcttat gtcgtcattt ttacagactg ccataatatc cgtgattata
     7981 aaaagggcgt tgttccggct cttggggagc tttatcagga agatgtcgat ttgattaccg
     8041 gaaaaagtta aaagaaaggg gctatatgcc cctttactgt taaaagggga gaatatctca
     8101 atatgaagat aagaaaaggt gacagacaat attatctgaa taaagaaggt gatacgtttc
     8161 atctggtgaa gcgagtaaaa actttttcta agtctgcgac tttaggaaaa acgaaagcaa
     8221 cggtgaaaac tgttgctgat cttgtttttc atgaggaggc attcgacact atcgactttg
     8281 ccagcgacgg attaagagag aatgataaag aaattgtttc tatgatgatt caggaaatga
     8341 gcgaggaaaa aaaatgctaa ctgaaaacac accagaaaac attaagcgtc tgcggcaaaa
     8401 aattggcctg acacagaaag aatgtgccga aatatttagc atgagtccgc gtacctggcg
     8461 tcgcaaagaa gaacctgtcg gaactgcaag cggtacagca cttacaccag tagagtttaa
     8521 atttcttctg cttttagctg gagaacaccc tgattatgta ctttgtaaaa ggaataaaaa
     8581 gaattctgat tctggaagta attaaggaat attaagatga aaatagaatt aacgtatgac
     8641 gaaatcacgg aataagctac aaaaaccata actgaattta tggctggact ttatagcccc
     8701 agttgcattg aacaatgagc aattgcgccc gtagctcgct gacgctcaca cgcgcagtac
     8761 agcgtcccgc cctgctgcaa tgcaccagga cggcgtaaac tcgctggcgc gagcgctaac
     8821 tgcggcattc tgcggcgcaa atcagcgtca tcgttgtctg tgagtcagtc gggcctggca
     8881 gggcgggaag gtggacctgg ttccggtcga taacagtagc ggcgttgccg cgcttcgggg
     8941 cgatgtggct cctgtgctac cctggtattt tcgttcgccc cttacatccg ctggcgcgga
     9001 taaaaagcgt gacaatcatc aaataattta ccgattttca ggccagaaac cttgctaata
     9061 catctaaata gatgtattct tgtttcatcg aaaggggaat ggctcctttc cttcttaagt
     9121 ccaaacggac aggagatttt aaatgaaatg ctcacctgtt tttacttcaa ccacaaacca
     9181 cgttttcaca ttcgaacgag taacgctttg cacgattgtt cttattcata aggatacggg
     9241 acaacagtat gttgtcatat ttactgataa caataaaatt cgtgactata agaccggaat
     9301 tgtttctcag tttggtgaac ttaagcagag tgatattgat ttaattcttt tctatcggga
     9361 cgaatatgaa aaatattttg actcgttaaa taatggcgag gagtatttaa gttttaaaga
     9421 atatatcgga tgtataaggg ggaaataaat tatgaaaggt gtgttcaggt tgctggaaca
     9481 acctgaacac gttatcgaca atcaaaactg aatgaggttt ttaaatgtca acacgacaga
     9541 tcgtacagct tgctgattct cttgtcaaag gctgggaaac cagaatcccg gcaatgacgt
     9601 ttagtgagtg ggatcaattc cggtggtggt taaactacct gcaagggtat gaaatgtttt
     9661 aaataaaaag gggcatttct gccccttcat atatttagac aaaaatgcta tatgtaacta
     9721 tagtcgtctg caagtaataa aggggggcag gggatgatta atgaagctaa aaaaattgct
     9781 gtggaaatga tgttttggac agcttgtccc gtggatgatg ataattgttt tgatgctatt
     9841 attaatgcat caaaaattga cagagaattt gaagataaac atgcgattta tcttcatccg
     9901 atttacaggg atttattatc aacagatcaa ataaaaagtg ctctgaaaaa gagagcaata
     9961 aaaataattt ccttcaagtg tgatattaat gaggattcgg caagaaaaat tttaatgcaa
    10021 accatattaa gagcggttta acttctggtg tgttgcaccc gtagctcgct ggcgctcaca
    10081 cgcgcagtac agcgccccgt ccagggaaac cctggacggc gtaaactcgc tggcgcgagc
    10141 gctaactgcg gcattctgcg gcgcaaatca gcgtcatcgt tgtctgtgag tcagtcgggc
    10201 ttagcagggc gggaaggtgg cccaggttcc ggttgataac agtagcggcg ttgccgcgct
    10261 tcggggcgat gtggctcctg tgcttccctg gtattttcgt tcgcccctta catccgctgg
    10321 cgcggataaa aagcgtgaca atcatcaaat aatttaccga ttttcaggcc agaaaccttg
    10381 ccaatacatc taaatagatg tattattatt tcatcgaaag gagattggct cctttccttc
    10441 ttaagtccaa acgggcagga gattaaaaat gagttcagaa gtgattaagc aaattcagaa
    10501 aattcaagat cgcggcatta tcatctattc aaagtttaga gcggcagaat ttgatcagga
    10561 tgacgtttac agagagtcat attttctggt cgtagagttt aacgagttaa tagcagaaaa
    10621 catcattcat gacgaaaaac tggtagatca aacggcttgt attcttcatg agcttagaag
    10681 aatcgctata gaagggaaat aaatataaca ggggcttatg ccccctgtta ttaactgatg
    10741 cagaaatagt atctggtaac ttatgaaggt gaagatgatt gatactttcg atagtgaaaa
    10801 atttctctca gagctggatg ttttatcaaa agagatcatg cctggttgtg gtcttgtttt
    10861 tgagctatac caacgtcgtt tgagtgctgc gattgataaa gttgtcgccg gattgccgga
    10921 agaacaacac gcccaggcgt ttgaactggc tcgccaggaa tttgattatc tttctgcgga
    10981 agagattgct gaagaaatac gccgtgactc agaacgtggc tattgttgtc acggctttga
    11041 tcgcgattgc tgccctctcg gttgcggtga tttaccatga aatacgggaa ggggcttgta
    11101 gccccttctc acaagcgcta ttcagatctg gccgtcttct tcttcctcgc ccactcgctc
    11161 actaccgttc ggtcgctggg gctgtggtca gcgtttgtaa gtttttctcc aatactgacg
    11221 acgtgcttcc tgatgtgtat tattgcgtaa taatacacat tattactgtg ttaagtctta
    11281 aatgtgtggt taatgctaat gtatgcatac attagcatta agtttgttgc gctgaacgta
    11341 caataattct ctatatccaa actgacccca aatatgccgc gccagcggca tggaaggcgg
    11401 cactctgtag gtgcatgtgg ctttgctggt tatccgccga agccccgcgc gagcgggtac
    11461 attgttgagg atatgacaga cctttctctc gccctgctaa gccatacccg ctttcagcca
    11521 tgatgaagta agagtgcgcg gtcggagtgg tcccgacaag ggtttacccg cagtcggggc
    11581 gtatctccgc gttagtgggc cgtgagggcc gcttacgagc gtgtacagag aacattcagc
    11641 gatgaaagaa tttacacatg tgtgtatgtg tgtgtattat tgttttcagg ttgggaggat
    11701 atatgaaatc tgctgacctg ttgaaagaac tgatagctgc tggttgcgag ttgaaacggc
    11761 ataaggcaag cagtcaccag atatggtggt cgccaataac aggaaaaact tttcctgttc
    11821 ctcatcctaa aaaggacttg ccgccaggta ctgtcagatc gatcaaaaaa atggcgggga
    11881 tttaatcccc gccgactttg gaggtagcca tgtttttttc tgtgggtgtt gaaacaccga
    11941 aggatgatca aatcgcatac ggtattaccg ttccggcttt tgatcgcttt gattttggat
    12001 gtgtttctgc ggctgattct caggcagaaa tacccgtaat ggcgcgtgaa gcgatattgg
    12061 caattgttga agagatggta ttaagcggtg ctcattctct tgatgatatt catgacgaag
    12121 ggtatttggc ttattctgat aacataaatt atagtcactg tgatagctgg tttgtaattg
    12181 atgtcgattt atcagaagtt gagggtaaac agcagcgtat taatatttcg ttgcctgata
    12241 tattgattcg tcgtattgat ggatatgtga aagaaagtgg cggtgtatac aaagatcgta
    12301 gtcattttct tgctcaggca gcacgtcatg aacttacata caaatgaaat tatccctgcg
    12361 ctatgcgggg atataaagca tttttgacaa atcaaaagaa attgcgtaca taatctaatc
    12421 cttatttagc atcaggatct tgtaataatt tagagagttt atatacctct ttttcgcctg
    12481 tttgaatgag aataatattg actaaaatat caccatcagg taattcctta atttcttctc
    12541 caacctgata gggagggcca aatgcaccga acgttttaac tgcacctgtc ggaatctgtg
    12601 ttgtattcat aaatcgtacc tcgcattgtt taagatatta tcgcacattt ttgtcacagt
    12661 tgctttaata ttgtcggtct tcgaccggaa acaaccacgt ggctgtaggt ttcgtgcgtt
    12721 ttgggcttag cagggggcgc gagcgcagtt ccagagaata tagaagacag tacccgctgg
    12781 cgcggggctt cggcggataa ccagcaaagc cacatgcacc tacagagtgc cgccttccat
    12841 gccgctggaa gcggcattta agattaagtc aggagtttat agagaaaaaa tccccacatt
    12901 gtgaattgta agacagtgct aataaataat gcagcaccac aataaaattt aaatgatttc
    12961 acgctggatt taaaagcatt attaattgct atatcaatat tcttagatat actttcacct
    13021 ttcttttcaa ggcttctgat atcattaaca taattagcta aggctttttt attaatttca
    13081 gccaggtttg tatctatggt agatattatt ttatttgctg actctattgt ttctgttgtt
    13141 ttttctgcaa cttttgtaat gttatcttga agctcttttg cactttctgt taatttttca
    13201 gttgcattaa ttcgagcttc ttccagagag cctttcactt cccccttact ttcctgaaat
    13261 tcgtcatgaa gggctactgc tgcgagttgt agttgtgacg ttttctcatc aatagcgtcg
    13321 ggtaatgagt taattgcttc agtaatgtta ttaatatcgt tacgtaaatt ttcgaagtat
    13381 atattgttct gttcctgaat tttcacagga taatttttta taagttcttc taattcatga
    13441 aacccttcga caaggcgttc tatggctatt ttcctcatca cttcatcttc ttgcaatgct
    13501 tgccaggctg ctttagtgtc ttgtatttta tccatagttt aacctcaaat gatattcagg
    13561 gcatcaaagg catgttgcat ttgtttttga taagaattaa aacctaactt atagaatttt
    13621 tgtaattcaa gaacaatctt ttctttaccg gtttttcctg ctaattgttc atccagttca
    13681 cttattgtag ggtaatcttt aacgttgtta taggttaagt tcgctcgttc cagagtttta
    13741 aatagagttg aatcgcttat acacggcgta tcctctgtga tttcgaaaca tacagattta
    13801 agttcttcgc tttttaatat tgttgagaat tgttctttta tgtctttttt tatatttacc
    13861 ctgttgaaaa ttacttttat tttttcacac gccacaccaa gttcaataaa ttctattatt
    13921 gtttttatag tatcaatttg ttgttttgca tcaggcgtta caggaataat aaagtaatcg
    13981 ataaaactat gggatcctgc aaagtcaaag gtaagttttg atttgaacgt ttcaatattt
    14041 gaagaaccaa catcaattat aacgtcgtcc agatttaaaa tcgtattgaa aattttatca
    14101 aaatcttctg ctgccatttt ttgaccatta ccttcaccat cggagtttaa tgtttctatt
    14161 ctcagaattt cataattgag gcgtggtaat agcatatgct ggctaatggt ggttttacct
    14221 acattaccgc tataatttaa tactgcaatt ctcatgtata attactcctg ttttatccga
    14281 tacatatgtg agttatgagt tcgatcccat tcactttctt ttttcttgca atattcacga
    14341 actttatcat ttataataga agggtccatg atattaattt gtaaaccccg atattcatct
    14401 tttgtcacac catagcgaat caataacacc ttagatgatc tagggatatt tatatcttcc
    14461 cattcaagga gagcctcttc agtaaactct tttttgggat agatgagacg accgagttga
    14521 tctcgttcct gacgttcctc tgccttttgg atggatgaac caacttttga accagctttt
    14581 gatgatggtc tttcaacgac ttttgtaagc ggacttttta cgctgtcagt agtatttttc
    14641 ttcgctcgtt cagtcatatt cctgtatgta cgaacactca gcttgctatc agtatgttta
    14701 tttatatatt cacatatctg ttgccaggta tgtgtttttt ttacttcaag taaatcatgg
    14761 agatacatac tgaacagtat ctgctttgat ttgacttttg cgttttttat ttcatcacat
    14821 agcggaccta agagactatc aatggttgcc atttatcacc tctgaatttt cctcctaata
    14881 tgacaaatcc acctcaaaat ttcaataacg tgttttggag tcaaagtgta agtcaaagtg
    14941 taagtcaaag tataagtcaa agtataagtc aaagtgtgag tcaatagcgg tttttgagtc
    15001 aaaatgtaag tcaaaacatg agtcaaaatg taagtcaaag tgtaagtcaa tgccaaagtg
    15061 ccacaacaat actgaaaaaa gacaggcacg agagcgattg ttaacaaaca caattagtgt
    15121 atgttacaat cgacgtgctt agggggattc ccctaatacc cctagtccat atctacaacc
    15181 aggtcgtaat ggaggttcta cgaaccatga aaaccaaaga aaaaaaatct gctgaaaaca
    15241 aaagcatcat gattggcttc agactgacaa atgaagagta ttcaaaattt gcatctgtta
    15301 tagaagaaac aggagtcagt aaatcagagt tttttcgact tgtcattacg ggaaagtttg
    15361 acccaaatgt gcatggaaaa gtaaagaagg ataattacag ggaattactc agacttttta
    15421 ataagtcaag taataatatt aatcagatag ccaaaaagat taatatggaa tatcgtaatg
    15481 gatttatttc tgaaaacact tatttacgtt atcttaatgt tctggtcaat attcgtgatt
    15541 cttttgttac cgggatagaa aaatgttagt cagaatcaac ggtggcaata agggggtatg
    15601 cgaatacctt gaaaaaggtt ataagcaagg aagggaatac acccgtgatg aaattgacca
    15661 tcggttagtt ctggatggtg atcttgcatt gactgaatca gttattgaca ccatacctga
    15721 taatggtcag gaacgttata tccacattac gttatccttt tttgaagata atgtttctga
    15781 atctaagttg catgatgtcg tccaggaata caagtccctc atgatgaatg cttatcatga
    15841 agatgaatat aatttttatg cggaagcgca tcttccaaaa ataaaacaaa tgcctgatta
    15901 taaaacagga gaaatggttg agcgtaagcc tcatattcac attgttattc ctgaagttaa
    15961 tctggtgaca gggagtaagc tgaatccaag aggaatgaca gaacattata tacaatatct
    16021 tgatgcaata caggagcata tcaataataa atacaatctt gtttctccta aagatggcgt
    16081 cagggttagc gatcataacc atgctaatgt attatccagg gctaaaggcg atttttaccg
    16141 tgagcggcac agtgagttta aaagcacggt ttttgatgca ctggatacag agaatatccg
    16201 aacagagaaa caatttgctg attatctttc ccgttttggt gaggttaagg agtataataa
    16261 gggggagtct aatcgctact ttggtgtgaa gcttgaagga gattcaaagt ttactcgact
    16321 caagagtcct ttattttcac gacagtatat atctgatcgt tctatcccac ttttaaaacc
    16381 cacaaagacg cagattgaga gccgtctgaa agagtggaag agttcggtca gtcatgagat
    16441 aaaacatatt catccggcag ggcaaaaaat tcgtaaagaa tatgcagcac ttgctggtga
    16501 atataagcaa atgtatctga aaaaggtaat taatcgttat gacgaaaaac acaaccttca
    16561 aagacaggac cgacgacaga atagtgacca gtccggtatt aaatacaata ccggaaagtt
    16621 tgtatccggt aagacaatcg gattgccacg tctgccagca cgcgaactgg tttacggact
    16681 tcacggaaga tcaggtggga aaagcattaa taaatctcag ttgttattgc agcaaaatga
    16741 atacggtgat ttatcaacgg ctggacgaca aaaagtcgat ccagatcgat atgtgcgacg
    16801 gttgcaggat agagcaggaa gaagagtagt tcagtcaccg cttgaatcaa atattaaagc
    16861 ggcgattcag cgcagtgatg atttaccttt tttgaaacaa attcgcacag aaattaatgc
    16921 tgaacgttat ttatccaatc tgcaaacacg ctttaacatt gatccatcaa agcatactgt
    16981 cacctatgca caggatggat ctccgcgttt cagagttggc aatagaaata tgaatgccag
    17041 tgatttttta actaaacatc tgaatcttga atgggatgag gcaaaagagg tattacttga
    17101 tatctggcag gatcagaaag ataacaaacc ttttgatgct gttattaccc gtgtaagtct
    17161 cacgcgtcaa caggcaaaag aaagatttat ttgtttaaat gaacataaag gttgggtaaa
    17221 taatgagatt aaatataagc ataatgataa tatagctaat tacagggcag aactcagagg
    17281 gcttctggcg ataagaaaca agcaggaacg ggaggttgct agagggtaca ttatatttaa
    17341 aaagctggaa agagagcgtg aaataaactc aattcgaaag gcatgttttc gcgaaataaa
    17401 ctcatactat caccgttgga atccagacag gagatatgat atggctttag gtgattcttt
    17461 aaaaaagata atccgtaatc cggttgatgg aaacagcatt tcttccggta atgaaaagga
    17521 agttttcagc gtagttaagc gagtacagca atcccagcaa gttcaggatt acgtaaaacg
    17581 tgaactaacc gatcttgttc ctcataaggt cagcccaaaa gaaacgcgtt accttgatcc
    17641 gaagacaacc caaactgttt tcactgataa aggaaatcat gttcgtgtaa atggtgaaat
    17701 tactcaggat aaagctgaag cagcccttct ttatgcaaaa gagaaatttg gcgggatgct
    17761 gaaactcaat ggctcggaag aatttaaggt agcctgtgca atggcggcag ccgagaaggg
    17821 gatgaatgtt attctgcgac ctgaaaaata tcatgaaatg atgcaggtcc gcctccagga
    17881 actgaaagct gaacatggac atgaaaacag cgtcgaggca gagcgtcagc agcaagtcgc
    17941 cggacagaaa ccggaacagg agcaggaaaa gagagcagag caggttaatt cagtcgagaa
    18001 agacacccag gctaaggaaa gaacgcccga agtagcggaa tctgtacgta atgatgataa
    18061 atcgcgtgat gcagtgccgg aacagcctgt taagtcagaa attgtttctc aaaaatccac
    18121 gtctgaaaca tccgtggtac aggaagcgga aaaacaggag tctgtgcaga agaacgtttc
    18181 ggctcattct gaagaacgcg agcagcagct acaagaagcg cagcaacaga agccggtaac
    18241 agagaaagac gtgacaactg gtcaggagaa acagaccgga gatgagcaaa gcaaatcagc
    18301 gttaaccact gaaaatcctc agcagcaaaa taacgcatcg ctacagcagc tacaggaaga
    18361 ggcaaaagtt attgccagcc agcaccagga agcccagcgt ttactgaatg aagctgtaga
    18421 aaatggtgcg ccgaaagaag aggttgatct gctttcgaaa ggggttaaca gtatttcggc
    18481 tcgtgctcag acgattaatg aacagattaa agcctttgag gaacaacaag ggcagaaaaa
    18541 agctaaatca gtcgaggaaa aaaacgagaa tactacagaa aagaaaaagc ggactgtcaa
    18601 tagtgaaaaa gcgatggaaa gagaaattga gcgagtttct aagcaactgg cgaaggaaat
    18661 gaatattgac aaacaaacag tcaaagatac gctcaaattc atacgttttg aggatgtaaa
    18721 cgatctcaag gcagcaatga aaaaccctga aacggtagag gccgtgaagc gtgaaattgt
    18781 gagttatgac aacgcattga aagatgagcg tgagcgggaa agaagcagag ataacactcg
    18841 cacccgttaa tcagaaacca aaaagcccga ctggtaatcg ggctttttgg tttttccggt
    18901 cttgagttgg tggctctgac cggaggaaga cactcagtat ccaacatcca taatattatg
    18961 gcactagaca ctggatgtct agtttgtgtg acttcagatt gtttgttaag aataattttt
    19021 cgatgaattt tatgggggga tctgtataat ttttgcgttg gtgctgtgtg cttcccttgc
    19081 taaaacctgc gctatgcagc tatgaacgaa ttaagtcctg gctgaacaaa caggtggtgc
    19141 tgtgttcggt gctctggcag gagtaggaca ctcagtatcc caacagataa cgagaaccgt
    19201 tgtgacaggc aatgtatgag taagcaatgg cgtctctact ccattgatgg agtaaacgga
    19261 tgattaacct gttaatcatc gttctcagag ccgtagtcgc cgttgcaaac gcgctgattg
    19321 cggttctgga actgattcgc gagttcatcg attgatgaca gcggaaacgt aactaagggc
    19381 aggggctaac cacctctgcc ctttaatctt ttcctttcaa tttttttgtt gcggtcgctg
    19441 atattcagtg tgttggccag ctgctcaatg ccaaagccga caatcagatg attttttatt
    19501 tttcataaag ttagaatctt tgttgtgata gataatgttg tcaatttttt tgattaatgc
    19561 gtatgagacc tcaatttatc tgattttggt taaaaaacag ccagccaatg aattctgcca
    19621 acaggctggt taaacgagtt ttgtcccccg ggtttgtgca aagttatcca caggaattgt
    19681 ggttaacgct ctaaaaaatc gctttaacat tgtcggtctt cgaccagaaa caaccgtgtg
    19741 gctgtaggtg tcgtgcggtt ttggcttggc aggggcgcga gcgcagttcc agagaatata
    19801 gaagacagta cccgctggcg cggggcttcg gcggataagc cgcatagtca tattgagcta
    19861 cagagtgccg ccttccatgc cgcaggcgcg gcatcattga gcgggaaaga agcagggaga
    19921 acacgcgctc tcgttaacat aatagctttg gtggtgtggt aggtgggaga cccatttcga
    19981 ccagcttcag cctacttcaa ttcggcaata gttccgcagg cctcgccact tcacgtgtga
    20041 catattcccg tccatgaacc cttcaccaca ccccaaagcc aactactctt tggttcccca
    20101 atagatatga agaacattca ttcctttaaa tcaataacaa attctatcat gcatccggtt
    20161 attattgaag tgttaatatt tacaatacca ccacccgtca ttttttttct caagaaccag
    20221 acatattctt tttgtatctt ttgataagat atcattacag aattttattg gtaatgtgaa
    20281 agttccaaat gataacctaa cgccttctga ctcagagtct gttagtttta atctgatctc
    20341 ttttgactcg taatttattt cagtagtcac atatttttta ttttcccgaa cagccacagt
    20401 caggtagcac cctgcgcctc ctgattttgt tctccttata actattctgt tttcccccaa
    20461 atgtctgtat gactcaactt gtcttgtcat tttaataaaa ttcataaata tctctttaaa
    20521 ataataatgc ctgttacaag gacaggcgtt atggattaat cagaatgatt agttttattc
    20581 tttatttgat gaaggttgag aggaagtttt ttctaaatat tctttaaaat atttttcttt
    20641 ctgttcttta gaaatgcaat taacatcatt tttatttttt atacatgcat catctgcctt
    20701 tttattatca caaccagata ataaaaaaga aaatataaca gatatcgctg caataaaaaa
    20761 ttttaacata aataacctca ttaattctat gttgcataaa ttaaaactct ggctttctgg
    20821 tcgtttttta atggacgtac ttccagacac cagaaggaac cttgtcatag agtttgttca
    20881 ttaccagttc tgcgcggcga tgatctgcgg cagaataaaa tgcctctgat tcagataaag
    20941 gaagtttgta acggttaata tcaataactt tttcaagagt atctcttgat gtacattttc
    21001 gtaactgaaa aatccattcc tgctttgttt tcatttatta atcctcgcgg aagggggaca
    21061 aacttaccat ttttcatatt acatctacca ttgctaccca tccagatgta tcaaggttat
    21121 tttacccgat ggttaatttt tatcaactat cgctactttt tgggaataaa ctcaaacccc
    21181 aactttccgg ttgccttatc catcagcttg accttagccg aaaactcttt gttcgtcctg
    21241 gaactgataa atccttttaa ctcgcctgta ataccttttt tcagcaatgt ttcgacttgc
    21301 ttatcagaaa gagccttgcc agagaagttc ttccatattt taaattcaca tccggtacag
    21361 aaatagcctt tcggcctgat aacaatttgt ttgccgcatg aaggacaggg ggaatccagt
    21421 tgttgagatt gccctgctgg cgcagcttca atcttcatct cgcccaggtc aacgtcagaa
    21481 atcatgcctg tgagttcatc gtatagttca ttaatgaact cttcaacggt cagctcgcca
    21541 ttttcaatag ctgtctgctt ttcagcccat aatgccgtca tatcaggatt aaccgctata
    21601 ccaggcaggg catcaataag cgcatatccg gtatcagtcg gaataagttt ccctttttcg
    21661 agagtgatat agttcctttt tttcagggct tcaagcatag ccgcacgggt agctggcgta
    21721 ccaatgccgc catgttcatc ttttttgtct ttatctttat ccttcagtaa tttttttatc
    21781 actggatcag tgacgaaatc agcgacacga acaagcgcag caagcaatga tgcctcagta
    21841 aataatggcg gcggtgtcgt tttcttctca ttaacaacca cttcttttgt cgtcagtgtt
    21901 tcaccagtgc gaattttaca aagctgttca aaagcggaat catcattatc tgattcatcc
    21961 tcgtttgtgg tttccgtgcc aagaaatgcc tcaaatccgc tgtcagttgt ttttctggca
    22021 cgggcataaa acgactcatc accacactga atggcaacag agacttcctt atacaatttc
    22081 tctggcatga actgaacgag atagtgttgt gcaatcgcca ggtaaacatt gcgttcgttg
    22141 ggtgttagtg cgtttatatc aggcacatta gcggtcggga ttatcgcagt atgtgccgtc
    22201 accttcgcgc tgtcaaaagc cttgctttta cgtgttgtat caacattcat tggctgatcg
    22261 aaaactgact tcagggcatc gataacctgc ggcgcttcgc tgaattgttc atcagaaaga
    22321 tatgaacaat cagagcggtt ataagtgatc gctttatatt tttcgcgtag ttgctgcgta
    22381 atatccagcg tcttttgtgc cgtcagtttg aactttttgt tcatgtactg ctgaagccgg
    22441 accaggttaa agggcaatgg tgcagccgtt tttttatcat cagttgctgc tgcttcaact
    22501 gtagccggtt ttccggtaag ggatgcagcc gttccgtttg cccatgcctt atcaagcaat
    22561 ttacgatctg tcagcggagc aaattcgcct ggtttccagt ttgctctgat aacatcagcc
    22621 ccacgctgaa agactccggt catggtgtag tagaaactgg atttgtggtt ctggttagcg
    22681 cgggtacgat taacaatcag gccaagaatg ggggtctgga cgcgccctac tgaaagtgta
    22741 cctttgtatc ctctggcctg tgccggaatc gtgtaagcac gcgtcataga gaagccatag
    22801 acggcatcgg caactgaacg cgccagcgcc ttaaggtaaa gccctctgaa gtcacgatta
    22861 tctttcaggt ttgccagtgc ctttttcact gccggaagcg tgttgtcgtt aatcagaacg
    22921 cgcttaacgg gttttgtgtt ccccgcatat tccagaactt catcaacaag tagctgacct
    22981 tcttcatcag ggtcgccagc atgaacaatt tcagtcacgt ctccacgtct gataagctca
    23041 agaatcgtgt taacctgctt tgcggcactt tctactggct ggtatttgac ggggtaaaga
    23101 cgtaaaggga gtgtttcaac tttccaggct ttgtaatcag gattatagtt ttccggtggc
    23161 tgtgattcga taatatgacc aaagcagtta gtcacaatgg cattatcact ttcaaaccag
    23221 ccatcatgac gggtgaaatt gcccccaaga gccttaacaa tatcatttgc tactgcgggt
    23281 ttttctgcga taaaaagttt cattttgtta tcctttacac tgaattagtc tgtttgcaca
    23341 gcgaatagca cgttcttctg atattgcctg tttccagtta tcttcaccta caggttgtct
    23401 gaacctgcgt tcacagccat taaaagcaaa aatcccctca cggttaagta tattcgttgc
    23461 gatatcctgg tctttaattc tcaaaaaggc tgttacggca aaaccagaat acgaagcaat
    23521 ttttgaaata atgcattcat cagcttttat taacgctgca aaaggaacta tcttttgacg
    23581 tccacacgaa atcagaggga gtgtgtgaat atcataataa gctattgaat gacaatccat
    23641 gcgggtatca tcaatagctg ccagccagaa tcctgtctgg tcctttattt ttctgctaat
    23701 atcagaatct gaaacaccag gatttaataa atatccacca taacagacat ggaaggggtg
    23761 aacagattca tcaatatcag gaagctcttt taccggattt tctttccagt ccttcagaac
    23821 accgaactca agagcatcca gcaaaaactt tcgttcaaat ccatcaaaca atgcatattg
    23881 catatgaaac ctctcaaaga agctctgatt tgttgacctc atggtgaacc agttcaccat
    23941 tgcgtaagac aaacagataa gaaaactttc tttccttatc tttcagccag tttttgtatt
    24001 cagaaaggat aaacggccag tcatcagtgc tgtaatgaga ttcgatgaca ccagaataac
    24061 aacggctacc gtcatcactc ttttcacctg tgaatacaat accttctcct ggaatttcga
    24121 tataatgacc actgttccat tcagggaatg gggggatatc aaccgacatt tctgccgttt
    24181 tatagtcaat aactctcgac acacctatta ttatcgttat catctttttt agtctctacg
    24241 gattcattta aaccagccat acggatatgc agggaacgtc aaccaactct caatcagaaa
    24301 ttccgtttct tcattccagt aaaaataaaa tcctctttca ttgaaccaga cattaaaacc
    24361 attgatattg cctatttctt ttgcaccaga atataaacgc tcaacatagt aatcaggctg
    24421 aaatgaatcg aaagtcgttg ttctgacaaa ctcctgacgt gatgatttta atatggtgtc
    24481 acgttcatct tcagggtcca ccattgcacc tgtattaata tcaaaaccaa tatataaagt
    24541 tgtacccgtc atggcttgtt ttacgaattt cttccagagc ttattattaa tggttattac
    24601 atgctgctga attatatcta cgaactcttt tctgactata tcaccgtaat cctcgactct
    24661 tttttcagga acgctgataa caaactcaac agtatcacct ttatcatggt taaacagagg
    24721 ttttaaaagc tcttcgcttt caaaattact tctgaatgca gccacatcac gaacaaaaca
    24781 ggacatatat tcatattttt catccttaaa catcccctgt aaatcttcac catgttgcaa
    24841 ggcatactga cagactcgct catacaggga tgattccgtt atagtgacgt aagctgcacc
    24901 ttctgtcatt aaatcactga caggaatatc agcactaatc tgaacttcac cactgattct
    24961 tttattgaat cgttctttat cattttttgt catcattgtt ttatcctctg atttaaaata
    25021 ttgcacaaag ataaaaagac agagtcatta gtatcattaa taaagcgatg ataaccatct
    25081 caactgtttc agatgtatta atttttctgt atatggctct taataagaaa tgaatcgtta
    25141 tcactcagaa ggaaaagaaa caaaccataa acacagaatt gtcgagtaag tcatttaaag
    25201 aataaaacca gtgaccagca ggatagggta aaccaaaaga tgaatgtata tgcattttgt
    25261 gccttcttaa tttttaatat tctattctct ctgtgatatc cctctttatc atgttctgtc
    25321 attatttatg aaaataaagt gataaaggaa aaataaaatt ataaacaatc atttattaaa
    25381 gcttttcttc ggggtttagt aacttccgta ccaccaccca tcatctcttt tttttagtgc
    25441 aataacaatt ctgtcattat gaaaatattt atgaaaaatc tcctcaaaaa ctttgccgag
    25501 agaaaaacct ccacgactca tcttgtggcc ttctgttgaa ttagttgttt ttaatcttat
    25561 ttttttatgt tctggattta attctataat gatgaatata tcgtcacctc gtgctttttt
    25621 cgaaagataa caatttacaa taccgtttct tctcttttct tttcgtagta caagacgtgc
    25681 tgaattactt cgctccataa attcacgttg cctggtaatt ttaataaaag tcatcatatc
    25741 accttgttta ttattaattc cgctatcgtc gtaatccatt cagatttatc cccgctcaac
    25801 gaacttctgg atagtctcct gttcagactg acgagtgacg gacttgttaa ttgcatccat
    25861 tttctcctgc cagagacgcc ggatatcctc ttcatcacga ccagtcagtt ttttaccgga
    25921 caacaggcgg ttaagcagtt cctgtctcgc atctggtatg tcttcagtca gacgaataag
    25981 ccggagtact tccttacgat ttaataccat gcgagatctt ggtaataagg cataataata
    26041 aaaaatataa ccgcataccg cacaagagct gacaagaaac aggcacagat atttcagata
    26101 tgtgccagaa acgcagaatg tgataatcat acataaaata caggtaatga aaaaaccatt
    26161 gcctagcaat atatataaat gattatgttt tttgaaagtt ttctcatgtt catccagaat
    26221 taaatctatt ttttctgcat ctgatttatt catgtcattt tcccataatt gattctaggt
    26281 tgtcctgatt ccacaaaatt gtttttcccc gcaaaaccag gataaaaatg gcatctgcgg
    26341 ggaatgattc aggggcggga taatctcatg tttgaatggg taacaaatac tcgtagaatc
    26401 gatagggata acaataaaaa accattaatt aatgccattt ttatctcctg aatcccgctt
    26461 tatttttgat gttttaactc tttaaatgat atttcattaa tttgttcagt tacaatgtgc
    26521 tttggtttag tcctgaaaca agcgttaatg agagtttcaa tcctctttcc tgtcttaccg
    26581 acgaaaatta cagatgtaca attcataata tttgaggtgt cttttttcat aaatatgtcc
    26641 tcattatcca gaaaaggcgc tgccataacg ttgcataatc atatttaagg ttggctggtt
    26701 aacagccgta cctgaacagg tataaagaaa attctgtctt gcgccgtagg ttgcaccagg
    26761 attataaaaa ggtgtgtaga cacggatgtt aaagaatctc tgattcaccg caatacaacc
    26821 aggttgtggt gctccctgta ctttttcagc catacagaca agcacttcac aaggatctcc
    26881 ggctgcggat agtcctttta ttttggcact ggctggtagt atgaaagtaa gcgcagaaag
    26941 tagtgtgact gatatgagta aacgaggttt catatttata tctccgtgag gaagcccaca
    27001 gacaggcttt ttgaacaatt gctttgatat tgtcagtctt cgaccacaaa caaccgcgtg
    27061 gctgtaaatt ccgtgcggtt gggcttagca gggggcgcga gcgcagttcc agagaatata
    27121 gaagacagtg cccgctggcg cggggcttcg gcggataagc cacatagcca tattgagcta
    27181 cagagtgccg ccttccatgc cgctggaagc ggcatcatgg ttaatcacca ccgccaccac
    27241 catcaccacc atcatcatca ggaaaatatt ccttatcatc atcaaaatca tctttatcaa
    27301 aagcaggttg cgtcgctttc catgcttcct ccctttcccg ctggagcatt aactgacgaa
    27361 ctacttcatc ctgtggaata tccagtacag gtgtgtctat gatatttttt cgggaatatt
    27421 ttcttgcatt aacaaaaaaa gactcatttt tttgatcaaa actaacaatt ttatgtgaaa
    27481 taaacgggcg acaaaactca ctcattacga tttgtggtaa agaaaatttt gttttctctc
    27541 ctttgacttt aaatttctga tcccgtaaat caataatttc ttgcggtagc ataacagcac
    27601 gtttttcaat aactttattg cgggtagtgc tggggttttt gccagttgtc cggcttattt
    27661 gagtgcgaac gaaatcataa tacccgattg tttcagatac atcttttaca ctgtcatcca
    27721 cttttttagg tggatagaaa atttcaactg cacagttttt cagaatggtg tttcccccca
    27781 ttttcccgta accaagtttt tcatcaaata actgttccct gttttgcaga ataaacacaa
    27841 aacgcaggtt atagcccgca gtgaatgcca gggaaacctg aaccacgtcg aggcggccta
    27901 ttgaagtgaa ttcgtccagc atgagcgtac actgatattt cagagttgcg tcatgctctg
    27961 gcagagtacg cacgttttca ttaagcagtt gtgaaaaaaa caggttagtc agacgttgat
    28021 attgctttaa tgcgccagga gaaatgccgt agtagatcgt cattttttta cggcgcacat
    28081 cacgcatatc aaaatcgtta tcttccgtgg cagcagcaac gacagggttg gcaaacatcg
    28141 acatggtgcg gttaaagtcg agcatgatgc tttcttgttg ctcagggtct ttggcagcga
    28201 actgacggaa taggcggatg gtgtcatcgc ttaacggata ggtggaagga gccttgccct
    28261 gtttttcctc ttccggtaaa gcatggtagg ctttccagcg ttcagtgaga acttcattac
    28321 cccgacttct gatctcgttc agcatccatt ttgccaggct tgaaccgtca gtcggaatac
    28381 tcagtttcat caccgagttc atattaactt taaattttcc ctcgagttcg gtatcaagta
    28441 accacagcac cagactgata aagacgtttt tactggactc cacccaggtg tcgttttctc
    28501 cccctgtcat cggaaacaga atcaccgcga ttttttccag gtcgccaaac cggtataccg
    28561 gatcgcggcg aatatagtaa aggggattgt agcggtgagt tgtcagcact gtttccccgc
    28621 cgatttctcg tgcgtagccg tcaggactga agagataaac ttcctgcttt aacacatttt
    28681 tccggtatcc cgccgtctca agaaagtttt ccagtttgat atcaaggaac accatcgatt
    28741 cggtatacca gatgccgtta ggcataacga tcgagacacc tttaccgctt cgtgtcgggg
    28801 cgtacagcat cagaaactgc tgtccgctgt attgcagata gcgtgattta aaacgccctt
    28861 tgttttcagg catttttcct ataagcagtg acgggtattt ctgatttttc agttcctttt
    28921 cgtcgggaaa aaaaccgctg tctgccaggt cacgatcatt tgccagcctg gcgttaccgt
    28981 gcaccgtttt tttctcccga acggcgacaa acatcacgac agtcaggatg agtgcaatca
    29041 ggaacggaag cagagtccct gcaagtcctg caaacaggta ttttttgagg gatggttgcc
    29101 agccataata ggccagcgtt gataagtacg tactccattg caggttgtca gtcggtagtg
    29161 aggcgatttt caccagtata aaacttccca gccagccgga ggctgtcagg gccatcagcc
    29221 agactataag tacaggcagg acaagtttct ttttcttcat cagcttttcc gttgtcgtga
    29281 gttttttcac cggagagttg cacccgtagc tcgctggcgc tcacacgcgc agtacagcgc
    29341 cccgtccagg gaaaccctgg acggcgtaaa ctcgctggcg cgagcgctaa ctgcggcatt
    29401 ctgcggcgca aatcagcgtc atcgttgtct gtgagtcagt cgggcctggc agggcgggaa
    29461 ggtggacctg gttccggtcg ataacagtag cggcgttgcc gcgcttcggg gcgatgtggc
    29521 tcctgtgcta ccctggaatt ttcgttcgcc ccttctgtct gctggcgcag acgaaaacat
    29581 cacgcggcca gtaattgatt tttttccatt gggttgtagt agatctccgt catatgtgtg
    29641 tgtttgaaga acaccacaat atcgatggag gttttgatgg ttttcagtat gaagctgtgg
    29701 tccagggtaa gtcccaccgt ggactgtttt acaatcgacg caagacggga aatggcgtct
    29761 aaggcactgt tggcgtgaat ggttgtcacg ctgccttcgt gccctgtatt cagtacttcc
    29821 aggtaactcc atgcctcatc accacgtaat tctgccagaa agatatgatc cggtttcata
    29881 cgcattgccg cttcaatcag gtatcggggc tgtacgccgc cttgcttata gaacagatgg
    29941 acgtgattac gatggtttgg cagcgtcatc tcgtgcacat cttcaatggt gataatgcgg
    30001 cgatcacggg gaaagaggtc tgcaatggtt tttgcaatgg tggtttttcc tgatcccgta
    30061 ccacccacaa ccagaatatt cattctggcg gccacagctg cttctaaaaa actgatccag
    30121 gttctggggg cgcacctggt gttatcgaga aggtcaagta atgtttgttg cgaggcgctc
    30181 agggcgctca ggtttgcctg attcacaatg cgaacattgc tgaagcggtt gctgttaacg
    30241 taatcctcca gtgtgaagcg cctcagggaa ggtttacgta tggtgaatga gatacatctc
    30301 tcttcacagg ccggaggcat gataatctgc atacgctcac caccaggcat aaccagcgac
    30361 ttgatagggt gcagggtatc aaggggttct gcgctgttgt tgtatttgtt gattgcaata
    30421 gagagatcaa gcaggtcact gtatgaggct ccaggggctt catggtattc ccagccgtta
    30481 acgccttcgg taataatttc aaacgggcgg tttacgataa tttccgtaag cccctccgcc
    30541 tcaagaaagg gctgtacgcc cgtgctttca agaaacatgt taatcgtttc catcagcgga
    30601 ctccgtatac agaagaaaaa tcaatgttgc gtggcacaat gacagtcagc atttcgccct
    30661 gattcacgta acctgttggc ggaatgttga ttgaattatc aagcgtggtt ttcgccagtt
    30721 cactggacgt tccggtggta ttgttcatag tgaagtcgct gttgttttcg cgggaaagac
    30781 gtgaggttcc ggcagccaga gtgtcttcaa tgagagaaag cattaatgcg ccaccaaagc
    30841 gctcccagaa atgtgtatcc acccacgccg gaagccccga cgcgccgagg ctgtcagcac
    30901 cgagagcatt aatccgcact ctgacattgc ggtccttaac cattgtccag ttgacaaaca
    30961 cgcgtgccat tccctgtgta atggcttttg tctgttctcc ctggagttgt gcgccagcac
    31021 ggattaatac cgttttcccg tcatccgaga tcacatcttt ggttaactgg cagagcgtta
    31081 caccaggata tgtggtgaca atcattgttt tcaggacgca cggaaaagtt gttccagccg
    31141 aaagcagaaa gcgacgattt tttatgcggg atacagagcc atcagcaaag tcagcaccct
    31201 gtaaaaaatc accatcacca gaaacatttg tgttgtctga cgctggcgta gcgcctgccg
    31261 ttttttgacc ggaacttcca ggctgtgact gtgtgatccg gctgtcatca accattacgc
    31321 ttcccatcag acgacgctgt tctggtgtgg gtggggcatc gccattattt tgtgtatatc
    31381 cggtatcagc ttcgttttct gctggcagag tgacaccttt attttccttg ttttccggtg
    31441 gtgcttcttc cctggcttgt tcctcttctg aattaacgtt gtttttgact tcctctatgc
    31501 ttctggcgac gctttctttc aggtcatcaa gattttttgc ctgggtattt tgtgcataga
    31561 cctctgcctg tgcttttgtg gtcgcagttt cggtagtttc ttcctctccc gaggatgaaa
    31621 acacctttga taaaacggat gtcagaatga ctacggtaac aaaagcaaaa cctgcaagta
    31681 taaggaccgc ttttgccttt ttgtttccct gttttttacc ggagtggatg aaattccggt
    31741 tttgagcgtc ggtatccgcc tcctgcgtgt caatttcatc gagtttttca atcacaatat
    31801 cgttgttatt tttcatcgtt attaatctcc actctggttt cgccagtcag tgttccgctg
    31861 tcgttccagg ttcgcggtat atgacggttt gttctgactt ccatcacctc acctccgaga
    31921 cgcagtacaa aagctggcga aatttcgtgc acaaccatga tgtttttatc catatggtaa
    31981 ttaaccagtt gctccttacc gtccggtaag atcctgaaca caaccggaag gtctgccgcg
    32041 ccaggccagc ggaaacaggt cagacgcccg ttatcccaga tggcttcagg tttaattttc
    32101 cggccaccgc gtacttcata acgaccgtta ataacattcc cttcagtaca gggggcgaca
    32161 acacggctgc ggcctgtcat gacgttaggc ttcacgggtt ccggcggttt cggatagata
    32221 taccgcagaa gataggttgg gttctggtcc gtactgacta actggatgga gtagatccgc
    32281 ttgtttgtca caatggcgat attggtatca ggttcggcag ctttggggcg cagaaatata
    32341 gtgttacccc tgacggccgg atcccaggct tcaggatcac caatagcaag accagtatct
    32401 tcgctcttga tgatttcccc ctcttcaagc tcgataaggg ttacttctcc tgcctttgtt
    32461 ttgacaatgg ttacgtcatt ggggttatag acgatttgtt gtacgcgtct gtcaaaacct
    32521 gcggacgctg gcgtttttgc agcatgacag gtcatggtga taccggatat gaccagggat
    32581 aaaaggagtt ttcgcatcat catttcacca cctctggatc aatacggtat gagagaacat
    32641 ccagtccgaa cgggtttatc tggcgctcag cttcagttgt gattttgtct tttgcccaga
    32701 caaatttgat ggtggcaatc cattgtgttg gtgtgtagcc aggcgcgggt ttgccatcgg
    32761 gatcggtgat tgccttaaca agacgtccct gtgccgtgtt ttcgtcaaga aaggttatgg
    32821 actgaacgcg aacaagaatt ttgtagctct ttttcagctt atacagcgga gataacggac
    32881 cgtgaatcat gttgttatat tcagcgaata ccggagagga tgacatcagt tcaacggtat
    32941 tgagcatgtt ctgaatcgta taccagtcgt aaccttcgcg gttctccaga tagcgggtga
    33001 ggaagtagcg ggatatcgct tcatcatatg taccggaatc ctgactgaac ggggtgatca
    33061 catccgtgta gcccgttgtt ttgtctaccc gtaacagaaa tggttctgtt gttttcagcg
    33121 gggccataac tgcaagggct accgccattg cagccgcaga agcggacgaa aagaaaagcg
    33181 caaaacgcgt gatccgcagt gagcgcttca gttcgttatc acgatcacgc gcaaattctt
    33241 ttgctgcgtc caggacgttt ttttcaattt ttttatcgat ttctttttga gcgggtgttt
    33301 tacgcgcttc tgctttggat tttttaaaat attcttttaa acccattatt tatatccctt
    33361 cataatgtta tcgacgctgg tatataatgg ctcccatttt cctgtggctt caggtgcttc
    33421 agggggattt gttgcggtac atgcagaaag aaataagcag acaactgccg gaatgatata
    33481 tttatacata aaacatacct tttaagccgg ataaataaga gatgttactt gagataaacg
    33541 aatgaattat ccggctttga tgtttccatt aaagcgggaa gataaataat cttttgctgc
    33601 tgcggcatat tccctgttgc gctctcgcgc atccgttgcc gttttattaa agcccagacc
    33661 aagctgattt ctggtgttgt taccgatgcc acgcagagct tttatggcat ctccggttgc
    33721 gcttgtcaga ccgttaatac ccacaccgcc ggttaaggta cttatcagcg ctgatatttg
    33781 agcaaggagg aacttaccaa ttaagaatac aagagcaata caaagaacgc tccagatatt
    33841 tttagcaata gcatcgctgt ttatattgat ataattatta atatactgaa tcagtacctt
    33901 gaacagacag gcataggcga tattgaggaa tatatagtta aaacacgaac ccacccatgc
    33961 tgtaaacata ttgcgcgtgg taggccatgc agagaaaaag ataaagacac cgcctatgga
    34021 aagcagtatg ccaaccatca tttcagccat taataaatag gccgcgcagt aaatgacaaa
    34081 tccgccgcca gcaagagtaa gagtaatggc ttttaaaata aaaattgccc atgcccccat
    34141 tgaatcaaac cagccttttg ctttttgaaa ctcgttaaat tgttggatcc ccaaatctat
    34201 cagcctgtta agaaggccat cgatgacggc tccggtactg gctccgtcct gaccaataat
    34261 cctggaagcc acttcctgac cgcttccctg tacgaaagga acaatatagc taaggtacat
    34321 cccgccagcg gtggtcatgg caaaaacgag cgtcagtaca cccattcgtt ttacggactc
    34381 catcatcaca tcatctttgc gtgtgtacat gatttcccac gcaaagaaga caccgtagag
    34441 aatgacggcg gccccgaata gcggagaaac cagttgcata attgtctgaa aatttgtggt
    34501 cacgctgttc tgaattatcg aggataattc attgaacatg ggctggacga tttcgaaatt
    34561 cgcttttgta aaagcagcgt catttgatgc catcattatt acctgcaaaa gaaaacgccc
    34621 gtcacaggga caggcgttat gggttaatca gagagcattc agtttacacg tatatacaga
    34681 tcgttttcat catctctgaa ctgaagcgtg tttttatcaa ttaccctaat aaaatgtttt
    34741 tccctacctt gtccatcctc tttatcaccc aaccagtctc catctctgat aaggaatgag
    34801 ttagttgtcc cgttacgctc attacctttc ttgtcttttt ctacccatat ttgagtgtag
    34861 taattatcct ttttgtcgta tttgataatc cacttttcag gagcgtcgcc actgtcagga
    34921 tttttttcta tatatgttcc ggctaattca ccattatcac catcgcaacc agacagtaaa
    34981 aaagcaaagg caaggataaa accgccaagt agttttttga acatgagcta cctcctgatg
    35041 gtatatgtta aattaaatat cctatcaaac attctgttga aaatgtatat attataaagc
    35101 gatttgtgac tttcttatca gttaagagaa aagttacttt cagtatattt tattagttcc
    35161 gcttcctcac gtaatttacg ttcacgggcc atacgattga tttcggcctc attctgcgca
    35221 atttttaact gcatggcggc agtttcgaga agaatgttat tctgaagctc ttcacgtttc
    35281 tgtggcgtat cggctttact gaaagccttt tgagttgcct ttatcttttc tgcgcttttt
    35341 tccaggtcct tactcatcgc ttcgtatttc gtgatttcct caaactttga ttcgtactgg
    35401 cgtttgatcc tgtcgtactc ttttgtatca aaaccgtatt tagtagccat gcttcgaata
    35461 tcagcgtcgg taagctcctt cttcatatca ttccagaagt ctttcatgta ggattcagca
    35521 ctgccaaaaa tggcagaata atcggtgatc ccttccaggc gtcttttggt atccagcact
    35581 tcctgcttat aggcttcaag ctggctggtt gcaagatcaa cctgtttttt cagttcagca
    35641 atctggtcgc tggctttctt aatgacttcg acggttttgg cgatgctgcc agggtcttta
    35701 acgatgacac cgcctacaga acttgccaca gagctatatc ctgccagggc gacacccact
    35761 aacagggctg tcagggtctt tttcatttaa attcctctcg ctttaagatt gtcggtcttc
    35821 gaccagaaac agccgtgtgg ctgttggttt cgtgcggttt gggcttagca gggggcgcga
    35881 gcgcagtctc agagaacata gaagacagta cccgctggcg cggggcttcg gcagataacc
    35941 agcaaagcca tatttaacta cagagtgccg ccttacatgc cgcttgagcg gcatattgaa
    36001 cattttaatt cagagaatat attcaggtta atcgcaaaaa tgtattatgt aagcatataa
    36061 cttcaacaaa ggttaaccga tgatggaaat agtaaaatac aaaggtaaac tggaaattat
    36121 aagaaatatt atacgagata ccatgttagg taatctggcc cttgctgtac ttatctttgg
    36181 tatattttct ctcagagcga acaatcaagg cgtgatagaa gaattatttt catatgtatt
    36241 gatgtttggc tccgttattg tttttgtatg gctcattatg atggtttata tctattttaa
    36301 tgagttaatt aagaatgtaa ttatcagatg gatatttatt gttatatgga tagttccggc
    36361 agatatcgta cttatattca gctatatatg ggacaggttg tagttctcct ggactgtggc
    36421 ttcaggggat aaccaccgaa gccacatcgg gctacagagt gcgccttagt ttcagagtga
    36481 tttttccggc aatttgtctt ttagccgttt catcatgaag ggcagccaga cttcaggaat
    36541 atcgctgtta gcttcccgta taacgtcctc tatctgataa attccctcga taaacggggg
    36601 ataccagagt tcaggatcgt cagagcctat ttcctccctg attttttcgc acaattttat
    36661 ccctttcatt gagcaggaaa taacaggcag aaaatcgtca aatcccacca ggtccatttt
    36721 ggcaaaggca cttgagccac tttgtttaat cagcattgtt cggctttcga gtttcagctt
    36781 tttaagctgg cgaaattctt tttctgtcag cccaatctct ttatagccgc tgtatttggc
    36841 atcagggttc gggagcagga tttttgttgg tgtttgctga acgagagccg cgaaaatttg
    36901 acagttaatc gcgtcttccg gtgactgact ggtgagccac atcatttccc ccttcatacg
    36961 accagccttg agcgaagcct tgattaaggc ctgtgtcatt ggatagttac agggtttcca
    37021 gaactcttca acgatggaca gcatgagctt accgcctttc tgcattcgct ttttgtagaa
    37081 aaacagtaca gacagaatga cttcacacgc aggatgatca cgttcattga cggtttccag
    37141 gataacagtc gtgtcaaaac cgattttgct gtatttatcg ggatcgaatt tattttcttc
    37201 agagtccgta gcccaggaaa gagcgccatt atcccaccat ttagacagac ggaggttcag
    37261 atcggggttt tgtatacggg attgcagacg agcgaaacgt cgctggcgac gttcaagttt
    37321 cataaccatt tcaacggcgc ggtcgatttc ttcagcttca ctgtcgctac agtcgctgcc
    37381 atcgttatta acggcacaac gtttgaccca ctctttcagg aacgccatca gttcaggatc
    37441 gtcattgtca ccgatctgga agggattcag gccggaataa acaccttcag ccagagagaa
    37501 atactgaccc ccgaacattc tgattgccag ttccgtagag cggttgaagt cgatcacgaa
    37561 catatcaggg ttaaaacgct ggagaaacgc ggcagccatc atttcaaatg tggttttccc
    37621 cgcaccagta gcacccagca gcattgcgtg tcccgcgatc atctgacctg taacattacg
    37681 ccctggtgcg ctgtagtggg tgttgaacca gtaaaggccg tcagtcacgg ttttcagagg
    37741 cattatggca gagccatcac caatgggatt tcccgatttt ttgccgtagc tgtgattatg
    37801 gagcggcatc aggcagcaga cattagagag agtgcgctgt gtggcaaggg ggcgcagtgt
    37861 tgaggctggc agatgactga accaggcata aggcgcttca gacgttgcgc gaacaaaacg
    37921 aaatccccgt ccactggtga caaattctgc cgcgacttca gaaccgttat tactggcttc
    37981 atccggtgtg tttccgaaga cggaaaggac gctgtgccag gagccaaaaa cggtttcctg
    38041 gttgatgata gcttcctggg ccatatggag ttcggtctgt tgcgtcttac cagcatcctt
    38101 tacggaagta agtttgttaa gctgttgctc aatttttttg ctggattttg atagcgaatc
    38161 gggaataaag gattgcgtca ggataaactc aaatggcagg gataacagaa aattccactg
    38221 accaatctgc gagcctcggg gaacatcttt tactatataa ttggagcaaa atttattgtc
    38281 gtgtccgtta cggtttttta tttcaagagt atcaaaactg aaataaaatt tgctgttctt
    38341 aatgctttct gaaatttttg ttgcggataa cgggattttc tcaaaatcat gattaagtaa
    38401 ataattaaga taatttgtgc aaatatcaga aatacagcct tcactgatcc cgagcgtgta
    38461 aatattgtag tctttaaaac ctgtttcaat ttgtctgatg atatcttttg cttttttttc
    38521 gccagcatca atatcatcat aagggatgcc tgtagtgata aaatattctg ttctgagcga
    38581 tctttcaccg ttaaaagttt cacaataaaa atcgctaagg cgctgaagaa aaggattgtc
    38641 agggaattta tatctggcat ccattggtga atcacgtttt acaaggtgtt cccacagaaa
    38701 aactttttca cttttgcaga gtccaagaag agtttctttt tgcccgttaa agttgttcag
    38761 aatcatatcg tcagtcaggc tttcataggg aatgccttca ataagaaaag tgagaagtag
    38821 ttttttatct tcaagccaga tgatattttc atgaatatgt gagtgataag gggggataaa
    38881 attattagtg attttcttta tcgacatatt attcaacctt cagaacgtta tttgaacgaa
    38941 atcccttaag gcactgacct ttaaatttta gtgccctggc agacatggcg ttcgggtcat
    39001 cggcacacat ttgtttgatg gcaatcatta cgccgataat gacggaggga ataataagcc
    39061 cgtaaaaacc aatagtcagt atgccaataa aaaaagaaac catgagagca agcagacaca
    39121 gaataaaagg aatgattggc attcctttga tcattgcagg acgattcagg ccattgtagg
    39181 taagatagac tgccttaagt tcttcggctg ctttaatttc ttctttatcc aacttttgat
    39241 cctcatgatg aaccggaata cataacgtat tccggtgatt aagttaatta tttgaaaatc
    39301 tggtagcagg cttcagcagc caccacacaa ccacctgcta ttgcggcata catcagtgat
    39361 ttgagaacac cagcccagga gtccatttcc gtgtatgcct ggaatacttt ccagagaatg
    39421 tgtaaaaggg ctacaccacc aacaaaacca tatgcccaga ggcgcagttc tccgatgaag
    39481 gttgtacctt tatcaaggcc accaacacca gcagccaggg ccggatttga ggcaataaaa
    39541 aaggcacaaa caaataagaa gaacgttctg tataaattaa tggatttatg cacggttttc
    39601 tccgtaattg attaacataa atttgatgac ggtttaaaaa ggaagagggg ttttaattaa
    39661 tagcagtatt atcactcctt aaaatcgtgt gttttgaaat caccaaaaac atcccattta
    39721 tcatggctat catttgttac cataaaagga cgtggttttt ctgaatatga ttttattgcc
    39781 ggaatatcat aatgcgtatg taatccggct ttttcctcaa tgatatctat ataacttttt
    39841 ccattgcttt cttttacata accccgtttg ttattaccgg agtaataaca actcattgtg
    39901 tcacgtaata ttttttgttg ttcccctcct tttttttcat atttatccca gcacgttttc
    39961 agcactgccg cagccgcacg aatattcgta cagggagaaa aaactgactc atgagttaaa
    40021 tttaaagcct ggaaattacg gctgtttatc tgacccaggc cagcactgaa atttttttta
    40081 ttggcagtca gttttttggc gtgatgaaca gcttcctctt cagtggtaaa atatttactg
    40141 ccaccgtcgg tgacatttgc tatagcgtag ggattcccac cggattcagt cataataatg
    40201 gcacgcatgg tttcaggaga aacaccaggt gcgcactgac tgatcagtgt cataagtaca
    40261 gttgcggata tagacatttt ttgacaggta acgatggaag tttaatttaa cggaatattg
    40321 gcagtgccag attacttagg gatatttttt ctggatgaat aatatcttgc gctccttcgt
    40381 gagcagatat ttattatttc gctctcatcc tgaatcgtca gttttttacc ggataacagt
    40441 cggttaaata gttcctgttg cacatcagga taatgactac tcagaactat cagaaattga
    40501 atagactcac ggtctattat tacgtaatca cttaaaggat tgggcagaaa atgacagata
    40561 gaatcgatag cagcgactat atagagaatt aaacccaaag aaaaaccgac tataaaaata
    40621 tagaagatat tttctctgtt aaggtaacag ctaaataagc cgaatgatgt aatgatgaat
    40681 agaataacaa gacgtattaa cctctgtatt ttccataatt tgtggtggtc atcaatgata
    40741 ctgttgatag tgttaatatc atggggaata gactcaagaa ttgaatcata ccatttctta
    40801 ataaagtctt tgtcattcat ttcaaaatcc gacggataaa taagaagaga atacctgaga
    40861 ttactaccca ggatattgca atgaatacat ccacaaactc tatatcttct cttgtgtcac
    40921 tagttgatat agatgagcta aataattctg taatatctgg tgtgagagtg gcatcgaatg
    40981 aaaaccaaaa accggggaaa aggattataa tacatattct cagatatctg ttgatcttgt
    41041 cgaagaccat accgattaaa aaaactatat agattgagat aaataatggc catggaattt
    41101 ctatcataaa cacacctcag caaattatag aaaaatatcg cttcagcatt gtcggtcttc
    41161 gaccagaaat aatcatgtag ctgttggttc cgtgcgtttt gggcttagca gggggcgcga
    41221 gcgcagttct ggagaatata gtagaagaca gtacccgctg gcacggggct tcggcggttt
    41281 tactccggtg tcatatgcag caatggtgtg ccgccttcca tgccgctggc gcggcatctc
    41341 acgaccaacg gaaacgtccg gcagcgagcg cttttcggac ccctgttatt tcgctattaa
    41401 gtgattcctc tgaacgatta atcaggccgg attttgccag gccataaata accagcaatg
    41461 tgtcgtgtgt cagttgcaac tctgttttct ccgcaggttg atcccgatat atccagggag
    41521 aacatagagc tttttcaaca taatacagcc tggagatttt ttgttttggt ggaatataac
    41581 gggcatagcg taatttcttc aggttggctt ttgcttgtga catgacatgt taatctgttt
    41641 catcatttta tgatgtaaat ctttccatct tcacacttaa atgttttcga ctcttcagta
    41701 acatttaaat tgttttcaac tttttcgcag tgtgaaacgg cccattcata aaactctgtg
    41761 tcgctgtgtt ttttttctgt attgatcaat atactcgcga ttaacagaat cagtcccgcg
    41821 aaagaaaatg caacaacaaa tccggcaatg agtccatcat gataattatc cctcattatt
    41881 ctctcctgta tctgaatatg tttttcggac acagttaatc cccctttaca gggaatcgat
    41941 tttgataaag agaattaact atggtgaaaa atgtaaaaat gagtcgttac ctgttagatg
    42001 gcgcggcacg tcactctata cgtagcccac actgaacatt gtcagcaagt gctgtttttt
    42061 gcacacaatt aatcctcctc atgccagggc ttcaggcaat taccgctgtc caggggtgtt
    42121 aaagagcgta cgaataacgc cttgttcggg cgttcggctg atagcggaaa acttcaacat
    42181 ggagacttta aaacagtaca atagatcgtt caaggtggtt taggcgatct attattccgc
    42241 ataaagcaaa ataaaaagta taaaattcta aaatcagctt ttatattggt atgatagatc
    42301 gttgaataga tcattcacga tctaatattc taaaaattaa agaagtggcg aaaaaaaata
    42361 ctttttgatt gtttcatcgg cagtgccgga tgtgctgatt tggcgggatt ggtggaatga
    42421 gcgtcacgac aaacactttt caaatcggag ggctacaggt atattaagcg gcattcggtg
    42481 ttgatccttt ttgatcttcg cttaaatttg agaaatttgg tccccgtcat aggggataaa
    42541 ggtagggtgc gccataaggc attcaggtgt atggcaggag ttgaacgatt ccatgaagcc
    42601 ataaaaacaa acccccatcc tctttgcctt cgaacttgac ggaccgaaac aaagaaaatg
    42661 ggggtagggt aatcccttgg aagacagtat acatgatgct ttccccatta ttcaatatcg
    42721 tccggtgtaa aaatgcactg tgcgaaagcc ccgtcataag cagtcgctta tggcttccct
    42781 gaacagactt tcattacact gtagtgaagc tcattaccgt caggtaaaga atccgaatcc
    42841 ggtgttcact ccccgtgaag gagccggaac gttgaagttc tgtgagaaac tg
//
