LOCUS       NZ_CP074556            16323 bp    DNA     linear   CON 22-FEB-2024
DEFINITION  Klebsiella pneumoniae strain S37_CRE38 plasmid pCRE38_3.
ACCESSION   NZ_CP074556
VERSION     NZ_CP074556.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN16387655
            Assembly: GCF_027595745.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 16323)
  AUTHORS   Elam,L.P., Chittur,K., Addison,R.M., Lewis,S., Smith,B.A.,
            Anderson,D.J. and Sysoeva,T.A.
  TITLE     Characterization Of Recent Carbapenem-Resistant Enterobacteriaceae
            Isolates From A Large Tertiary Care US Hospital
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 16323)
  AUTHORS   Elam,L.P., Chittur,K., Addison,R.M., Lewis,S., Smith,B.A.,
            Anderson,D.J. and Sysoeva,T.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2021) Biological Sciences, University of Alabama
            in Huntsville, 301 Sparkman Dr, Huntsville, AL 35899, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. v0.4.7
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 330x
            Sequencing Technology             :: Illumina NextSeq; PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/22/2024 01:22:27
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,606
            CDSs (total)                      :: 5,485
            Genes (coding)                    :: 5,373
            CDSs (with protein)               :: 5,373
            Genes (RNA)                       :: 121
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 67 of 112
            Pseudo Genes (internal stop)      :: 14 of 112
            Pseudo Genes (multiple problems)  :: 19 of 112
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP074556.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..16323
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="S37_CRE38"
                     /isolation_source="BAL"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="pCRE38_3"
                     /geo_loc_name="USA: Durham, NC"
                     /lat_lon="36.0368 N 78.9000 W"
                     /collection_date="2017-11-14"
                     /collected_by="Rachel Addison"
     gene            397..678
                     /gene="drpB"
                     /locus_tag="KHW02_RS27855"
                     /old_locus_tag="KHW02_27755"
     CDS             397..678
                     /gene="drpB"
                     /locus_tag="KHW02_RS27855"
                     /old_locus_tag="KHW02_27755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019725580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DrpB"
                     /protein_id="WP_004151461.1"
                     /translation="MEEQAKRSPGGKLALWALYAFCGYCVWVIVRYWWVVGKIHSVPGA
                     SVEGDFGTTAGKWLGALLGMLVLGGIGSILGAVVWYTRPSRGEQDHQR"
                     /name="drpB"
     gene            721..1428
                     /locus_tag="KHW02_RS27860"
                     /old_locus_tag="KHW02_27760"
     CDS             721..1428
                     /locus_tag="KHW02_RS27860"
                     /old_locus_tag="KHW02_27760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="WP_002911594.1"
                     /translation="MDLVDWQQRFERWILTHHAQDDAAHDLSHFRRVWATATQLAAGEE
                     VDRLVLLTACYFHDIVSLPKNHPERSRSSMMAAEKTLAILQSAFADFPADRYPAVSHAI
                     EAHSFSAAIPPRTLEAKIVQDADRLESLGAIGLARVFAVAGALNTILFDAEDPFADRRA
                     LDDRKYALDHFQCKLLRLPETMQTDKGKAMAQHNARFLVEFMAKLSAELQGEPLALDEA
                     VLRRFAPQASTDR"
                     /name="phosphohydrolase"
     gene            1505..2905
                     /locus_tag="KHW02_RS27865"
                     /old_locus_tag="KHW02_27765"
     CDS             1505..2905
                     /locus_tag="KHW02_RS27865"
                     /old_locus_tag="KHW02_27765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="WP_004153246.1"
                     /translation="MSLAEQAGEHAEALLRQLMTIYDVKTLVAELVSVGEQHWSAAILK
                     RVAALGRAAERLRPQEVAHLATLLPSPPAHHPHYGFRFIDLFAGIGGIRSGFEAIGGQC
                     VFTSEWNKHAVRTYKANWYCDPQQHRFNEDIRDITLSQRSDVSDEEAARHIRESIPQHD
                     VLLAGFPCQPFSLAGVSKKNAMGRAHGFACETQGTLFFDVVRIIAARQPAIFVLENVKN
                     LKSHDQGRTFRIIMQTLDELGYEVADAGHTGPDDPKVIDGRHFLPQHRERIVLVGFRRD
                     LQLHAGFTLRDIAAQYPAVRPTFGELLEPTVDAKFILTPVLWKYLYRYARKHQARGNGF
                     GYGLVDPANPHSVARTLSARYYKDGAEILVDRGWDRPLGEKHFDDPLNQQRRPRRLTPR
                     ECARLMGFESPQGARFRIPVSDTQAYRQFGNSVVVPVFAAVAKLLAPRIAQAVARREAD
                     DNDGGCSR"
                     /name="DNA cytosine methyltransferase"
     gene            2886..3380
                     /locus_tag="KHW02_RS27870"
                     /old_locus_tag="KHW02_27770"
     CDS             2886..3380
                     /locus_tag="KHW02_RS27870"
                     /old_locus_tag="KHW02_27770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="very short patch repair endonuclease"
                     /protein_id="WP_002911592.1"
                     /translation="MADVHDKATRSKNMRAIATRDTAIEKRIAALLTGAGFTFVAQDRA
                     LPGRPDFTLPDYRCVIFTHGCFWHHHDCYLFKVPATRTAFWLDKIAGNVARDARDRQQL
                     AEQGWRVLIIWECALRGRLRLSDAALTERLEEWICGAGHDAQIDTQGIRELTTTSTPYK
                     E"
                     /name="very short patch repair endonuclease"
     gene            complement(3355..4266)
                     /gene="yedA"
                     /locus_tag="KHW02_RS27875"
                     /old_locus_tag="KHW02_27775"
     CDS             complement(3355..4266)
                     /gene="yedA"
                     /locus_tag="KHW02_RS27875"
                     /old_locus_tag="KHW02_27775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227747.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="drug/metabolite exporter YedA"
                     /protein_id="WP_004151459.1"
                     /translation="MSTRQLLPLIGALFALYIIWGSTYFAIAVGVASWPPLMMAGIRFL
                     AAGVLLLGWLLATGHKLPARRPLLNAALIGVLLLAVGNGFVTLAEHQHVPSGIAAVMVA
                     TVPLFTLCFSRFFGIATRKLEWLGIAIGLAGIVMLNSGGNLNGNPWGALLILIGSLSWA
                     FGSVYGSRIVLPIGMMAGAIEMLAAGIVLLAASWLSGETLTRVPSWSGIAALAYLAIFG
                     SLIAINAYMFLIRNVTPAVATSYAYVNPVVAVLLGTGFGGESLSLIEWLALAVIIFAVV
                     LVTLGKYLFPVRSEATPCKASK"
                     /name="yedA"
     gene            4450..5361
                     /locus_tag="KHW02_RS27880"
                     /old_locus_tag="KHW02_27780"
     CDS             4450..5361
                     /locus_tag="KHW02_RS27880"
                     /old_locus_tag="KHW02_27780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF808 domain-containing protein"
                     /protein_id="WP_002911591.1"
                     /translation="MAGSSLLTLLDDIATLLDDISVMGKVAAKKTAGVLGDDLSLNAQQ
                     VTGVRANRELPVVWGVAKGSFVNKVILVPLALLISAFIPWAITPLLMLGGAFLCFEGVE
                     KVLHSLEARKHKEDPERRQQRLAALAERDPLAFERDKVKGAIRTDFILSAEIVAITLGI
                     VAEAPLLNQILILSGIAILVTIGVYGLVGVIVKLDDMGYWLAEKRSALAQWLGKGLLAV
                     APRLMKVLSIVGTLAMFLVGGGIVVHGIAPLHHAIEHWSAGLGGVMASTLPVVANLVLG
                     FIIGAVVLAGVKAVSSLRGAGK"
                     /name="DUF808 domain-containing protein"
     gene            5477..7156
                     /gene="dgcQ"
                     /locus_tag="KHW02_RS27885"
                     /old_locus_tag="KHW02_27785"
     CDS             5477..7156
                     /gene="dgcQ"
                     /locus_tag="KHW02_RS27885"
                     /old_locus_tag="KHW02_27785"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004175394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis regulator diguanylate
                     cyclase DgcQ"
                     /protein_id="WP_002911590.1"
                     /translation="MDKPLRLKLKKCYHLARPAHVVNACFIAVLFFSTLLIWREINVLE
                     EAYVANQRNNLANVAHEMDGLLQFNIDRMMFFRHGMQAALEQPLDIDVLRKASQRYLSQ
                     RHQQAWRVALPNRRTLPVFGISGSVAGDNPILLVDDPLAADELMATLELGYLLNLTQHD
                     RDFAERMQYISRSGFFTSTLPLRDESQVITHYSQALSAPWFTRQTQRNNPGRGVIWQIF
                     PDDDPQLEEQVVTASIPLDFAGYWRGVLAMDFSVSEIKAFLVSAMQGGQVGEYQLYDSH
                     LNLLASSAPGNVLTLLSPREQELLSRAFVHDNQGGLRLLTRYISWAKLRNFDGVLLRIH
                     TLREGVRGNFGTITIALTLMWVLFTLMLLLSWLVIRRMVRNMSVLQTSLEWQAWHDALT
                     RLLNRGALFEQAMAVASDCQRSGRPLAVIQLDLDHFKHINDRYGHQAGDRVLSMVASTL
                     SSAVRQGDLLGRVGGEEFCIVMPNTTLQEAAAVAERLRQRIQGREVFLHNNVTLRVSAS
                     LGVSASEERGEYQFEALQSVADGRLYLAKQNGRNQVCFRSAA"
                     /name="dgcQ"
     gene            complement(7456..7677)
                     /locus_tag="KHW02_RS27890"
                     /old_locus_tag="KHW02_27790"
     CDS             complement(7456..7677)
                     /locus_tag="KHW02_RS27890"
                     /old_locus_tag="KHW02_27790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YodD family protein"
                     /protein_id="WP_002911589.1"
                     /translation="MKHQLTGQTGDDLDVNVDALLAAINEISESEVHRTLDDPQRASID
                     GRGSHTWRELAEAFELDIHDFSASEANR"
                     /name="YodD family protein"
     gene            7811..8002
                     /gene="dsrB"
                     /locus_tag="KHW02_RS27895"
                     /old_locus_tag="KHW02_27795"
     CDS             7811..8002
                     /gene="dsrB"
                     /locus_tag="KHW02_RS27895"
                     /old_locus_tag="KHW02_27795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DsrB"
                     /protein_id="WP_002911586.1"
                     /translation="MQVNDRVTVKTDGGPRRSGVVLAIESFSEGTMYLVSLEDYPLGIW
                     FFNEIGHPDGIFVEKEVS"
                     /name="dsrB"
     gene            complement(8035..8658)
                     /gene="rcsA"
                     /locus_tag="KHW02_RS27900"
                     /old_locus_tag="KHW02_27800"
     CDS             complement(8035..8658)
                     /gene="rcsA"
                     /locus_tag="KHW02_RS27900"
                     /old_locus_tag="KHW02_27800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227742.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RcsA"
                     /protein_id="WP_002911561.1"
                     /translation="MSTMIMDLCSYTRLGLTGYLTSRGIKKQEIVEVNSAADLQKHCTS
                     CCPAVVFLNEDCFVHDDESNGIIRQIITQNPATLFVIFMSLANIHFDRYLRVRKNLLIS
                     SKSITPKDLDVILVNYLKYKNTSVGQLTLPTLSLSKTESNMLQMWMAGHGTSQISTQMN
                     IKAKTVSSHKGNIKKKIQTHNKQVIYHIVRLTENITSGIQVNMR"
                     /name="rcsA"
     gene            9031..9465
                     /gene="yedD"
                     /locus_tag="KHW02_RS27905"
                     /old_locus_tag="KHW02_27805"
     CDS             9031..9465
                     /gene="yedD"
                     /locus_tag="KHW02_RS27905"
                     /old_locus_tag="KHW02_27805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein YedD"
                     /protein_id="WP_004189223.1"
                     /translation="MMKKLFFAGMVVALAGCVQVDRYEDVVKAPAPAGLAGFWQTKGPQ
                     SAMMSPDAIASLIVTKEGDTFDCRQWQRVIAQPGKLMNRDSEIYNVTASLDIYPVEREG
                     NTISYDRMTLSRVERLTPECEKAWAKARATGPVSAPASTR"
                     /name="yedD"
     gene            complement(9507..10994)
                     /gene="amyA"
                     /locus_tag="KHW02_RS27910"
                     /old_locus_tag="KHW02_27810"
     CDS             complement(9507..10994)
                     /gene="amyA"
                     /locus_tag="KHW02_RS27910"
                     /old_locus_tag="KHW02_27810"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004136602.1"
                     /GO_function="GO:0005509 - calcium ion binding [Evidence
                     IEA]; GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="WP_002911554.1"
                     /translation="MKNPTLLQCFHWYYPTGGELWPEVEALAPSLNEIGINMVWLPPAY
                     KGASGGYSVGYDTYDLFDLGEFDQKGSVATKYGDKAQLLAAINALKEHNIAVLLDVVVN
                     HKMGADEKESLRVQRVDEQDRTQIDEEIIECEAWTRYTFPVRAGQYSQFVWDYKCFSGI
                     DHIENPTEDGVFKIVNDYTGEGWNEQVDDELGNFDYLMGANIDFRNHAVTEEIKYWARW
                     VMEQTGCDGFRLDAVKHIPAWFYKAWIEHVQEVAPQPLFIVAEYWSHEVEKLQQYIDLV
                     EGKTMLFDAPLQMKFHEASRQGRDYDMSQIFSGTLVEADPFHAVTLVTNHDTQPLQALE
                     APVEPWFKPLAYALILLRENGVPSVFYADLFGASYEDTGGDGETYAIEMPVIEQLHELI
                     DARQRFAHGVQTLWFDHPNCIAFSRSGTDDDPGCVVIMSNGDEGEKTLTLGENYGNKRW
                     RDFLGNREEIVETDGEGCATFTCNGGSVSVWVLEEVL"
                     /name="amyA"
     gene            11195..11995
                     /gene="tcyJ"
                     /locus_tag="KHW02_RS27915"
                     /old_locus_tag="KHW02_27815"
     CDS             11195..11995
                     /gene="tcyJ"
                     /locus_tag="KHW02_RS27915"
                     /old_locus_tag="KHW02_27815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227739.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015276 - ligand-gated monoatomic ion
                     channel activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine ABC transporter substrate-binding
                     protein"
                     /protein_id="WP_002911552.1"
                     /translation="MKLALLGRQAMMGVMAVVLMAGVSVKTFAAENLLNQIKERGTLRV
                     GLEGTYPPFSFQGDDGKLTGFEVEFANELAKHLGVKADLKPTKWDGMLASLDSKRIDVV
                     INQVTISDERKKKYDFSTPYTVSGVQALVKKGNEGVIKTAADLKGKKVGVGLGTNYEEW
                     LRQNVQGVDVRTYDDDPTKYQDLRVGRIDAILVDRLAALDLVKKTNNTLAVTGEAFSRQ
                     EAGVALRKGNDDLLKAVDGAIADMQKDGSLKALSEKWFGADVTK"
                     /name="tcyJ"
     gene            12091..13077
                     /gene="dcyD"
                     /locus_tag="KHW02_RS27920"
                     /old_locus_tag="KHW02_27820"
     CDS             12091..13077
                     /gene="dcyD"
                     /locus_tag="KHW02_RS27920"
                     /old_locus_tag="KHW02_27820"
                     /EC_number="4.4.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227738.1"
                     /GO_function="GO:0019148 - D-cysteine desulfhydrase
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-cysteine desulfhydrase"
                     /protein_id="WP_002911550.1"
                     /translation="MSLQNLTRFPRLELIGAPTPLEYLPRLSDHLGREIFIKRDDTTPL
                     AMGGNKLRKLEFLAADALREGADTLITAGAIQSNHVRQTAAVAAKLGLHCVALLENPIG
                     TRAENYLSNGNRLLLDLFNTQVEMCDALTDPATQLDELATRIEAQGYRPYVIPVGGSNA
                     LGALGYVESALEISQQCEDAVAISSVVVASGSAGTHAGLAVGLEQLMPQAELIGVTVSR
                     SVADQLPKVVALQQAVANSLELQAKAEIILWDDYFAPGYGTPNEDGMAAVKLLAQLEGI
                     LLDPVYTGKAMAGLIDGITQKRFKDEGPILFVHTGGAPALFAYHPHL"
                     /name="dcyD"
     gene            13093..13761
                     /gene="tcyL"
                     /locus_tag="KHW02_RS27925"
                     /old_locus_tag="KHW02_27825"
     CDS             13093..13761
                     /gene="tcyL"
                     /locus_tag="KHW02_RS27925"
                     /old_locus_tag="KHW02_27825"
                     /EC_number="7.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine ABC transporter permease"
                     /protein_id="WP_002911547.1"
                     /translation="MQESIQLVIDSAPFLLKGAVFTLQLSIGGMFFGLVLGFILALMRM
                     SPVWPVKWLARMYISIFRGTPLIAQLFMIYYGLPQFGIELDPIPAAMIGLSLNTAAYAA
                     ETLRAAIASIDKGQWEAAASIGMTPWQTMRRAILPQAARVALPPLSNSFISLVKDTSLA
                     ATIQVPELFRQAQLITSRTLEVFTMYLAASLIYWVMATVLSSLQNYFENQLNRQERDPK
                     "
                     /name="tcyL"
     gene            13758..14510
                     /gene="tcyN"
                     /locus_tag="KHW02_RS27930"
                     /old_locus_tag="KHW02_27830"
     CDS             13758..14510
                     /gene="tcyN"
                     /locus_tag="KHW02_RS27930"
                     /old_locus_tag="KHW02_27830"
                     /EC_number="7.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416427.1"
                     /GO_function="GO:0015424 - ABC-type amino acid transporter
                     activity [Evidence IEA]; GO:0005524 - ATP binding [Evidence
                     IEA]"
                     /GO_process="GO:0003333 - amino acid transmembrane
                     transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine ABC transporter ATP-binding protein
                     TcyN"
                     /protein_id="WP_004151455.1"
                     /translation="MSAIEVKSLVKKFHGQTVLHGIDLEVQKGEVVAIIGPSGSGKTTL
                     LRSINLLEQPESGTIRVGDVTIDAGRSLGPQKGLIRQLRQHVGFVFQNFNLFPHRTVLE
                     NIIEGPVIVKGEDKQESMARARELLAKVGLSGKENSYPRRLSGGQQQRVAIARALAMRP
                     DVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMDQGRI
                     VEQGEAKALFASPQQPRTRQFLEKFLMQ"
                     /name="tcyN"
     gene            14828..15550
                     /gene="sdiA"
                     /locus_tag="KHW02_RS27935"
                     /old_locus_tag="KHW02_27835"
     CDS             14828..15550
                     /gene="sdiA"
                     /locus_tag="KHW02_RS27935"
                     /old_locus_tag="KHW02_27835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227735.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SdiA"
                     /protein_id="WP_002911542.1"
                     /translation="MRDNDFFSWRRDMLHQFQSMATGEEVYNLLQRETEALEYDYYTLC
                     VRHPVPFTRPRVTFQSTYPRAWMSHYQAENYFAIDPVLRPENFMRGHLPWNDSLFRDAP
                     ALWDGARDHGLQKGVTQCLTLPNHAQGFLSVSANNRLPGGYPEDELELRLRTLTELSLL
                     TLLRLEDEMVMPPEMKFSRRELEILKWTAEGKTSAEVAMILSISENTVNFHQKNMQRKF
                     NAPNKTQIACYAVATGLI"
                     /name="sdiA"
     gene            complement(15618..15842)
                     /locus_tag="KHW02_RS27940"
                     /old_locus_tag="KHW02_27840"
     CDS             complement(15618..15842)
                     /locus_tag="KHW02_RS27940"
                     /old_locus_tag="KHW02_27840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2594 family protein"
                     /protein_id="WP_002911541.1"
                     /translation="MSTPDFSTAENKQELAQEVSCLKAMITLMLQAMGQADAGRVIIKM
                     EKQISQMEDEAQAAVFSSTVKQIKQAYRQ"
                     /name="DUF2594 family protein"
ORIGIN
        1 tggttcttta tattaaattt ggatgtttgt gcaaaattta ttattttcat atatagcaat
       61 actttattct atctttggtt ggtcgttgtt aattttatga aataaattgt gcaaataata
      121 atcagacgca ttattcatta tggaaattta ttttttgtga atgtaaatat ccagggaatt
      181 atcaacccag cttgcgatat ttaaggaatg aatagctttc agcgtacggg agataataag
      241 gacatctctt cagcctgtgc gcattggcag cataagtcgc gagaaggcgc agaagacgaa
      301 gatgaaactg ctgcctgtga cgcaggttag cggtataatg tgatgcgtgt cacgttttga
      361 gtgacaatag tctgttgtgt cacggagagg aatgagatgg aagagcaggc aaaacgcagc
      421 ccgggaggga aacttgcgct ctgggcgttg tatgcttttt gcggatattg tgtctgggtc
      481 attgtgcgtt actggtgggt agtgggaaaa attcacagcg ttcccggcgc cagcgtggag
      541 ggtgattttg gaacaacggc cgggaaatgg cttggcgccc tgttgggtat gctggtcctc
      601 ggcggcattg gctctattct cggcgcggtc gtctggtata cgcgtccatc ccgcggcgag
      661 caggatcatc agcgctaaaa ttgctatgct cgaggctgac cctcagataa aggaaagcct
      721 atggacctgg ttgactggca gcaacgattt gagcgctgga tactgacgca ccatgcgcag
      781 gatgacgccg cacacgatct gtcccatttt cgtcgcgtct gggcgaccgc cactcagctg
      841 gccgcggggg aggaagtcga ccggctggta ctcctcacgg cctgctattt tcatgacatc
      901 gtcagcttgc caaaaaatca tccggagcga agtcgatcct cgatgatggc cgccgagaaa
      961 accctcgcca ttctgcagtc ggcctttgct gattttcctg cggatcgtta cccggcggtc
     1021 agccatgcca tcgaggcgca cagcttcagc gcggcgatcc caccgcgcac gctggaggcg
     1081 aaaatagttc aggatgccga tcgactcgag tcgctgggag ccattggtct ggcgagggtc
     1141 ttcgctgtcg ccggcgctct gaataccatc ttgtttgatg ccgaagatcc ttttgctgat
     1201 cggcgggcgc tggatgaccg caaatatgcc ctcgaccatt tccagtgcaa acttctgcgc
     1261 ctgccggaaa ccatgcaaac tgacaagggg aaagcgatgg cgcagcataa tgcccgtttt
     1321 ctcgtcgaat ttatggctaa gctcagcgcg gagctgcagg gggagccgct ggcgctggat
     1381 gaagcggttt tgcgccgctt tgcaccgcag gcgtcaaccg accggtgatt tatggtactc
     1441 tctgccaaaa tcgtccgcgt tggttgagga tatgccgcaa aagttaagca aggaacacag
     1501 gtcgttgtcg ttggctgaac aggccgggga acacgctgag gcgctgctgc gtcagctgat
     1561 gacgatctac gatgtaaaaa cgctggttgc cgaactggtg agcgtcggcg aacagcactg
     1621 gagcgcggcg atcctcaagc gcgtggcggc gcttggccgc gcggcggagc gtttgcgccc
     1681 gcaggaagtt gctcatctgg cgacgctcct gccttcgccg ccggcccatc atccgcacta
     1741 tgggttccgt tttatcgatc tgtttgccgg tattggcggg atccgcagtg gttttgaagc
     1801 catcggcgga cagtgcgttt tcaccagcga gtggaacaag cacgcggtac gcacctataa
     1861 ggccaactgg tactgtgatc cgcagcagca ccgttttaat gaagatatcc gcgatattac
     1921 cctcagccaa cgctctgacg ttagcgacga ggaggcggcg cggcatattc gcgaatctat
     1981 ccctcagcat gatgtgctgc tggctggctt cccctgccag cctttctcgc ttgccggcgt
     2041 ctctaagaaa aatgcgatgg gccgtgcgca tggctttgcc tgcgaaaccc agggaacgct
     2101 gttttttgac gtggtgagaa ttatcgcggc tcgtcagcca gcgatttttg tgctggagaa
     2161 tgtcaaaaac ctcaaaagcc acgatcaggg gcgcaccttc cgtatcatca tgcagacgct
     2221 ggatgagctg ggatatgaag tagctgacgc ggggcatacc gggccggatg acccgaaggt
     2281 gattgacggg cgccatttct tgcctcaaca ccgggagcgc atcgtgctgg tgggtttccg
     2341 tcgcgatctg cagctgcatg ctggatttac gctgcgcgac atcgcggcgc agtacccggc
     2401 ggtgcggcca acatttggcg agctactgga gccgacggtc gatgcgaaat ttattcttac
     2461 gccggtgctg tggaaatatc tttatcgtta tgcccgcaag catcaggcgc ggggtaatgg
     2521 ctttggttat ggcctggttg accccgccaa tccccacagc gtggcccgga cgctttctgc
     2581 ccgctactat aaagatggtg ccgaaattct cgtcgatcgc ggctgggacc ggccgctcgg
     2641 tgagaagcat tttgacgatc cgctgaatca acagcggcgg cctcgccggt tgacgccgcg
     2701 cgaatgcgcc cggctgatgg gctttgaatc cccgcagggg gcgcgttttc gcatcccggt
     2761 atcggatacg caggcctatc gtcagtttgg caactcggtg gtggttccgg tcttcgccgc
     2821 ggtggcgaaa ctcctggcgc cgcgcatcgc tcaggcggtg gcgcgccgcg aagcggatga
     2881 taatgatggc ggatgttcac gataaagcga cgcgcagtaa aaatatgcgg gcgatcgcca
     2941 cgcgcgatac ggcgatcgaa aagcggatag cggcgctgct gaccggggcg ggattcacct
     3001 ttgtcgccca ggatcgcgcg ctgccgggac gtcccgattt cactttaccc gactaccgtt
     3061 gcgttatctt tactcacggc tgcttctggc atcaccatga ctgctatctg tttaaggtgc
     3121 cggccacccg cacggcattc tggctggaca aaatcgccgg taacgtggcg cgcgacgccc
     3181 gcgaccggca acagctggct gagcagggct ggcgggtgct tatcatctgg gaatgcgccc
     3241 tgcgcgggcg ccttaggctg agtgatgcgg cgctcaccga gcgtctggaa gagtggatct
     3301 gcggcgccgg acacgacgcg cagatcgata cgcaggggat ccgcgaactg acgactactt
     3361 cgacgcctta caaggagtag cctcgctgcg gacggggaag agatatttcc ccagcgtcac
     3421 cagcactacg gcgaaaataa tcaccgccag cgccagccac tcaatgagcg acaggctctc
     3481 gccgccgaac ccagtaccga ggagcaccgc gaccaccgga ttaacatagg cgtagctggt
     3541 ggcgaccgcc ggggtgacat tgcggattaa aaacatgtag gcgttaatgg cgatcagcga
     3601 gccaaagatg gccagatagg ccagggcggc gatcccggac caggaaggga cgcgggttaa
     3661 ggtttcaccg ctcagccatg aggccgccag caggacgatc ccggcggcga gcatctcgat
     3721 tgcccccgcc atcatgccga tcggcagtac gattcgcgaa ccgtaaaccg agccgaaggc
     3781 ccagcttagg gaaccaatca ggatcagcag tgcgccccag gggttgccgt tcaggttgcc
     3841 tccgctgttg agcatcacga tacccgcaag gccaatggca atgcccagcc actccagttt
     3901 acgggtggcg atgccgaaaa agcggctgaa gcataaggtg aacagcggta cggtggcgac
     3961 catcaccgcc gcgatgccgg aggggacgtg ctgatgttca gccagcgtca cgaagccgtt
     4021 gccaaccgca agcagcaaca cgccgatcag cgcagcgtta agcagcggac gacgcgccgg
     4081 tagcttatgg ccggtggcca gtagccaccc cagcaacagc acgccggcag cgagaaaacg
     4141 aatgccggcc atcattagcg gcggccagct ggcgaccccg acggcgatag cgaaataggt
     4201 agagccccag atgatataca gcgcaaacag cgccccgatg agcggtaaaa gctgacgggt
     4261 agacatactt cctcacgacg gtgcagagat agaaagggga catatagtaa acgtgaaaac
     4321 tatcgtgctg gcgagtggtt aatttgcgtc aggttgttaa atttatattg actaattgta
     4381 ccttgggcac cggccgtttt ttaacgcata ctcgagggag acattgatga aaagagaagg
     4441 aaaatcattt tggcaggaag tagtctttta acattacttg atgatatcgc cacgctgctg
     4501 gacgatattt ccgtgatggg caaggtagcg gcgaaaaaaa cggcgggggt gctgggcgac
     4561 gatttgtctc tcaatgccca acaggttacc ggcgtgcggg cgaatcgcga gttgcccgtg
     4621 gtctggggag tggcgaaagg gtcgttcgtt aataaggtga tcctcgtgcc actggctttg
     4681 ttgatcagcg ccttcatccc ctgggcgatt acgccattgt tgatgttggg cggcgcgttt
     4741 ctctgtttcg aaggggtgga gaaggtactg cacagtctgg aagcgcggaa acacaaagag
     4801 gatcctgaac ggcggcagca gcgtctcgcc gcgctggcgg agcgcgatcc gctggccttt
     4861 gagcgtgaca aagtaaaagg cgcgattcgc accgatttta ttttgtccgc ggaaattgtc
     4921 gccattaccc tcggcatcgt ggcggaagct ccgctgctta accagatcct tattctctcg
     4981 gggattgcga ttctggtcac tatcggggtg tatggcctgg tgggggtgat cgtcaagctg
     5041 gacgacatgg gttactggct ggcggaaaaa cgtagtgcgc tggcgcagtg gctgggtaaa
     5101 gggctcctgg ccgtcgctcc ccgcctgatg aaggtgttgt ccatcgtcgg gacgctggcc
     5161 atgttcctcg tcggcggggg gattgtcgtt cacggtattg cgccgctgca tcatgccatc
     5221 gagcactgga gcgcggggtt gggtggggtg atggcctcca cgctgccggt cgtcgccaac
     5281 ctggtgctgg gttttatcat cggcgcggtg gtgctggcgg gcgttaaggc ggtgagcagc
     5341 ctgcgtggcg ctggaaagta gcatggcgaa acgcagcgta acggcgccgc gtgttctacc
     5401 ctgaaaacgc cccgggtatc gacagagacc ggggcgctga cgccgcgagg tttgcgcaac
     5461 gtactgcgag agaaagatgg ataagccact gcggttgaag ttaaaaaagt gctaccacct
     5521 ggctcgcccg gcgcatgtgg ttaacgcttg ttttatcgca gtgctatttt tctccacgct
     5581 gctgatctgg cgtgaaatca atgttctgga agaggcctac gtggccaacc agcgtaataa
     5641 tctggctaac gtcgctcatg aaatggatgg gctgttgcag ttcaacatcg acagaatgat
     5701 gttttttcgc catgggatgc aggcggcgct cgaacagccg cttgatatcg atgtattgcg
     5761 taaggccagc caacgctatc tgagccagcg ccatcagcag gcctggcggg tggcgctacc
     5821 gaatcggcgt acgctgccgg tgtttggcat ctcgggcagc gtcgctggcg acaaccctat
     5881 cctgctggtg gacgatccgc tggcggctga tgaactaatg gcgacgctcg agctgggcta
     5941 tctgctaaat ctgacgcagc acgaccgcga tttcgccgag cggatgcagt atatctctcg
     6001 tagcggcttt tttacctcga ccctgccgct gcgggatgag tcgcaggtga taacgcacta
     6061 ttcccaagcc ctcagcgctc cgtggtttac ccgccagacc caacgaaata atccggggcg
     6121 aggcgttatc tggcaaatct ttcctgacga tgacccgcag ctggaagagc aggtggtcac
     6181 cgcttcgata ccgttggatt ttgccggtta ctggcgcggc gtgctggcga tggatttctc
     6241 agtcagtgaa atcaaagcgt ttttggttag cgccatgcag gggggacaag tgggagagta
     6301 ccaactttat gatagccatt tgaacctgct ggcttcttcc gcgccgggga atgtcctgac
     6361 cctgctgtcg ccgcgcgagc aggagctgct gagccgcgcg tttgtccatg ataaccaggg
     6421 agggctgcgt ctgctgacgc gctatatcag ctgggccaaa ctgcgcaatt ttgacggcgt
     6481 gctgctgcgg atccacactc tgcgggaagg cgtccgcggg aactttggca ccatcaccat
     6541 cgccctgacc ctgatgtggg tcctcttcac cttgatgctg ttgctctcct ggctggtgat
     6601 ccgccgcatg gtccgcaaca tgagcgttct gcaaacctct ctggagtggc aggcatggca
     6661 cgatgccttg actcgcctgc tcaatcgcgg ggcgctgttt gaacaggcga tggcggtagc
     6721 cagcgactgc cagcgcagcg gacggccgct ggcggtgatc cagctcgatc tggatcattt
     6781 taagcacatc aacgatcgct atggtcatca ggcgggggac agggtgctgt cgatggtggc
     6841 cagtacgctg tccagcgcgg ttcggcaggg cgatctgctg ggcagagtgg gcggagaaga
     6901 gttttgtatc gtgatgccga ataccaccct gcaggaagca gcggcggtgg cggagcgatt
     6961 gcgccagcgt atccagggac gggaagtctt tttgcataac aacgtgacgc tgcgggttag
     7021 cgcctcgtta ggggtgagcg ccagcgaaga gcggggggag tatcagtttg aagcgctgca
     7081 gtcggtggcc gatgggcgac tctatctggc caagcaaaat gggcgtaacc aggtctgttt
     7141 tcgcagcgca gcgtgagtaa aacgtttcga tgtcgattgg caaaatgaga attatcttaa
     7201 agtgatcgca ggcgatcgcg ctatcgaatg aaaccggttt gcggctaagc cttctcacat
     7261 cagccttgca gcccgataag tcatcaagcg ccaacattct caatattttg cgtcatgaat
     7321 atctcttgtc atgcaaaata attgaggata atgtttcaac gcatcggatt tcccggtgta
     7381 acgaattttc aagtgcttct tgcattagca agtttgatcc cgactcctgc gagtcgggat
     7441 ttttttcgcc tgccgctaac ggttggcttc actggcgctg aaatcgtgaa tatcgagttc
     7501 gaatgcctcc gccagctcac gccaggtatg tgacccgcgg ccatcaatgc tggcgcgctg
     7561 cgggtcgtcc agcgtgcgat ggacttcgct ttcgctgatc tcattaattg ccgccagcag
     7621 ggcatctacg ttgacgtcaa ggtcgtcccc ggtctggcct gttaattggt gcttcatcat
     7681 taccccctcg ctgagcgtcg ctcaagcctc tctaagtata gtcggtctaa aaaagcgcca
     7741 gtcacgtgcc gcgacgctgc gagttgcgtg gttttgttct acactggctg aaaatataga
     7801 ggagatgatt atgcaggtga acgatcgtgt cacggtgaag accgacggtg gcccacgtcg
     7861 atcgggggta gtgctggcga ttgagtcgtt tagtgaagga acgatgtatc tggtttcact
     7921 ggaagactat cctctgggga tctggttttt taatgaaata ggccacccgg atgggatttt
     7981 cgtggaaaaa gaggtctcgt aaaactgaac tggcgggagc gccgccagtt tgtttcagcg
     8041 catatttacc tgaataccgg aggtgatgtt ttcggtcagc cgaacgatat gataaatcac
     8101 ctgcttatta tgcgtttgta ttttcttttt aatattgcct ttatgcgacg ataccgtctt
     8161 cgctttgatg ttcatttgcg ttgagatttg cgaagtacca tgcccggcca tccacatttg
     8221 cagcatattt gattctgttt tactcagtga caatgtcggt aaagttaact gccctacact
     8281 ggtgtttttg tatttaagat aattaaccag aataacatca aggtcttttg gggttatcga
     8341 ttttgaactg attagcagat tcttccgtac ccgcaaatag cggtcaaaat ggatgttcgc
     8401 cagcgacata aagataacaa acagcgtcgc cgggttttgc gtaatgatct ggcgaataat
     8461 gccattactt tcatcatcat gcacgaaaca gtcttcattc agaaacacca ccgccgggca
     8521 acacgacgta cagtgtttct gcagatccgc agcactgttg acctcaacga tttcctgttt
     8581 tttaattccc cgactggtca gatatcccgt caatcccaac cgggtatagc tgcacaaatc
     8641 cataatcatc gttgacatga cccatcctca atcaacacgt aacgatatac acttcgcact
     8701 ggctgtgcga agcagtcctt gcgggcgata ataatagtag gtttagaaag aacccattag
     8761 ctccattaaa ctattccgca tctatgcata taatttgcca ggaaaactct taaagtaaag
     8821 tcaagaaccg gtagtgtgac cgaattaaaa acaaaaagtg cccatagatg ctatggttac
     8881 gcgcccagta ttcttttact ttcagaattt ccttacttca aatgaaaccc acgttagcgg
     8941 ttgctggctt gctcgcttat ccctttgcgg tgggggtgga aggcttaacg ctttaatgcc
     9001 acaatacttt tttatcggct tgtgggatga atgatgaaaa agttattttt tgctggcatg
     9061 gtggtggcgc tggccggttg cgtacaggtt gatcgttatg aggacgtggt taaagcgccg
     9121 gcgccggctg gccttgcagg tttctggcaa acgaaagggc cgcagagcgc gatgatgagt
     9181 cctgacgcca ttgccagcct gattgtcacc aaagaagggg acaccttcga ctgccgccag
     9241 tggcagcgcg tgattgcgca gccggggaaa ctgatgaatc gtgacagtga gatctacaac
     9301 gtgaccgctt ccctggacat ctatcctgtc gagcgcgagg gcaacacgat ctcctacgat
     9361 cggatgacgt tgtcccgtgt tgaacgtctc actccggagt gcgagaaggc gtgggccaaa
     9421 gcgcgagcga cggggcccgt cagcgcgccg gcctccacgc gctgagattt tggcgggcca
     9481 tagctggccc gcccggcgtc agaggactac aatacctcct ctaacaccca cacgctcacg
     9541 ctccccccgt tacatgtaaa ggtcgcgcag ccttcgccat cggtttcgac aatctcttcc
     9601 cggttaccga gaaaatcccg ccagcgtttg ttgccatagt tttcgcccag cgtcagcgtc
     9661 ttttcgccct catcgccatt ggacatgatc accacgcagc ctggatcgtc gtcagtaccg
     9721 ctacgactaa aggcgatgca gttaggatga tcgaaccaaa gggtttgcac gccatgggca
     9781 aaacgctgac gggcgtcgat cagctcgtgg agttgttcga taacgggcat ctcaatggca
     9841 taggtctctc cgtcgccgcc ggtatcctca taggaagcgc cgaagagatc ggcataaaag
     9901 accgagggca cgccattctc ccgcagcagg atcagcgcat aggcgagggg cttgaaccag
     9961 ggttcaaccg gcgcctcgag ggcctgcagc ggctgcgtat catgattggt gaccagagtg
    10021 acggcatgga aagggtcggc ttccaccagc gtcccgctga aaatctggct catgtcataa
    10081 tcgcggccct ggcgcgacgc ttcatgaaat ttcatctgca gtggggcatc aaacagcatc
    10141 gttttgccct cgaccaggtc gatatactgc tggagcttct ccacttcatg ggaccagtat
    10201 tccgctacaa taaacagcgg ctgcggggcc acctcctgaa catgctcgat ccacgcttta
    10261 taaaaccagg cggggatatg cttgaccgcg tcaagacgaa aaccgtcgca gccggtctgc
    10321 tccattaccc agcgcgccca gtatttgatc tcctcggtca ctgcatgatt gcggaaatcg
    10381 atattggcgc ccatcagata gtcaaagttg ccgagctcat catcgacctg ttcattccat
    10441 ccttcgccgg tgtaatcgtt gacgatttta aacacaccgt cttccgtcgg gttctcgatg
    10501 tggtcaatgc cgctaaaaca tttgtagtcc cagacaaact gcgaatactg tccggcgcgc
    10561 accgggaagg tgtagcgcgt ccatgcctcg cactcaatga tctcctcgtc aatttgcgta
    10621 cgatcctgct catcgacgcg ctgaacgcgc agagactctt tttcatcagc gcccatttta
    10681 tggtttacca ccacatccag cagcacggcg atattgtgct ccttcagggc gttgatcgcc
    10741 gccagcaact gcgctttgtc gccatatttg gtggcgacag accctttttg atcaaactcg
    10801 ccgaggtcaa agagatcgta ggtatcatag ccgacggagt aaccgcccga ggcgcctttg
    10861 taggcgggtg gcaaccagac catattgatg ccgatttcat tcaggctggg cgccagcgct
    10921 tcgacctcag gccacagctc gccgccggtg gggtagtacc agtgaaaaca ttgcaataag
    10981 gtggggtttt tcatcttcca tgctccagac gtcaacaggc tgacctttgc agtatgggag
    11041 atatccagca aaaagggtga ggaaagccct gattttcgct ataccctaaa gcggatcata
    11101 tataataaat ttgcataaga tgtagcgtaa cgatgttggt gtcagggcgt taagcgcctt
    11161 acactacagg aaaatcctaa ccttcggggt atctatgaaa ttagcacttc tgggtcgtca
    11221 ggcgatgatg ggcgtgatgg ccgttgtttt gatggctggc gtcagcgtga aaacttttgc
    11281 ggcggaaaac ctgctcaatc agattaaaga gcgcggcact ctacgcgtgg gcctcgaagg
    11341 cacctaccct ccctttagtt tccaggggga tgacggcaag ctgaccgggt ttgaagtgga
    11401 attcgctaac gaactggcga aacatcttgg cgtgaaggcc gatctcaaac cgaccaagtg
    11461 ggacggtatg ctggcctcgc tggactccaa gcgtatcgac gtggtgatta accaggtcac
    11521 tatctctgac gaacgtaaga agaaatacga tttctccacc ccatataccg tctccggcgt
    11581 gcaggcgctg gtgaagaagg gtaacgaagg cgtgattaaa accgcggcgg atctgaaagg
    11641 caagaaagtg ggcgtcggac tgggcactaa ctatgaagag tggctgcgtc agaatgtcca
    11701 gggcgtggac gtccgtacct atgatgacga tcccaccaaa taccaggatc tgcgtgtagg
    11761 ccgtattgac gccattctgg tagaccgtct ggcggcgttg gatctggtga agaaaaccaa
    11821 caatacgctg gcggtaaccg gcgaagcctt ctctcgtcag gaagctggcg ttgcgctgcg
    11881 taaaggcaac gacgacctgc tgaaagcggt agatggcgcg attgcagaca tgcagaaaga
    11941 tggcagcctg aaggcgctgt ccgagaaatg gtttggcgct gacgtgacga aataacggac
    12001 agcggtgaaa aaaggcgctc ctggaagcgc ctttttttat ttagcgcgta actgtgtgca
    12061 taatgaagca taactgagtc aggaggggcc atgtcactgc aaaacttaac ccgctttccg
    12121 cgcctggaat tgatcggcgc gccgacgccg ctggagtatc tcccgcgtct gtccgatcac
    12181 cttgggcgcg aaatttttat taaacgtgat gatacgacgc cgctggcgat ggggggcaac
    12241 aaactgcgta agctggagtt tctcgccgcc gatgcgctgc gcgagggcgc ggatacctta
    12301 atcaccgccg gcgcgatcca gtctaaccat gtgcgtcaga cggcggcagt cgctgcgaaa
    12361 ctgggactgc attgcgtggc gctactggaa aatcccatcg gcaccagggc ggagaactat
    12421 ctgagcaatg gcaaccgtct gctgctggat ctctttaaca cccaggttga gatgtgtgat
    12481 gccctgaccg atcccgccac ccagctcgat gagctggcga cccgcattga ggcgcagggg
    12541 tatcgtccgt atgttattcc ggtcggcggc tccaatgccc tcggcgcgtt aggctatgtg
    12601 gaaagcgcac tggaaatcag ccagcagtgc gaagacgcgg tggcgatctc gtcagtcgtg
    12661 gtcgcctccg gcagcgccgg cacccatgcc ggattggcgg tcggccttga acagctgatg
    12721 ccgcaggcgg aactgattgg ggtgaccgtg tcgcgctcgg tcgctgacca gttgccgaaa
    12781 gtggtggcgc tgcagcaggc cgtggccaac agtctcgagc tacaggcgaa ggctgaaatt
    12841 atactgtggg atgactactt tgccccagga tacggtacgc caaacgaaga tgggatggcc
    12901 gctgtgaagc tgctggcgca gctggaaggt attttgctcg acccggtcta taccggcaaa
    12961 gcgatggccg ggcttatcga cggcatcacg cagaagcgct ttaaggatga agggccgata
    13021 ctgttcgtcc acactggcgg agcgccggcg ctgtttgcct atcatcctca cctctaatac
    13081 agaaacgaca gcatgcaaga aagtatccaa ctggtcattg attccgcccc ttttctgctg
    13141 aaaggggccg tctttacgct gcagctgagc attggcggga tgtttttcgg cctggtgctg
    13201 ggctttatcc tggcgctgat gcgcatgtcg ccagtctggc cggtaaaatg gctggcgcgc
    13261 atgtatatct ctattttccg cggcacgccg cttatcgccc agctgtttat gatctactac
    13321 ggcttgccgc agttcggcat tgagcttgac ccgatcccgg cggcgatgat cggcctgtcg
    13381 ttgaatactg cggcctatgc ggcggaaacg ctgcgcgcgg ccatcgcctc gattgataaa
    13441 gggcaatggg aagcggcggc cagtatcggt atgacgccct ggcagacgat gcgtcgggcc
    13501 attttacccc aggcggcgcg ggtcgctttg ccgccgctgt cgaacagttt tatcagcctg
    13561 gtaaaagata cctcgctggc ggcaacgatc caggtgccgg agctgttccg tcaggcgcag
    13621 ctaatcacct cgcgaaccct ggaggtcttc accatgtatc tggcggcctc cctgatctac
    13681 tgggtaatgg cgacagtgct ctcctcgctg cagaattatt ttgaaaacca gctgaaccgc
    13741 caggagcgtg atccgaaatg agtgcgatag aagtgaaaag cctggtaaaa aaattccatg
    13801 gccagacggt gctccatggt atcgacctgg aggtacagaa aggggaagtg gtggcgatca
    13861 tcggccccag cggctcgggc aaaaccaccc tgctgcgtag catcaacctg ctggagcaac
    13921 cggagagcgg cacaatccgc gtcggcgatg tgacgatcga cgccggtcgt agcctcgggc
    13981 cgcagaaagg gctcattcgc cagctgcgcc agcacgtcgg ctttgtcttc cagaacttta
    14041 atctgtttcc ccaccgtacg gtgctggaga acattattga agggccggtc atcgtaaaag
    14101 gtgaagataa gcaggagtcc atggcgcggg cgcgcgaact gctggcgaag gtggggctca
    14161 gcggaaaaga gaatagctat ccgcgccgtc tctccggcgg gcagcagcag cgagtggcta
    14221 ttgcccgcgc gctggctatg cgtccggacg tgatcctgtt tgatgaaccc acctcggccc
    14281 tcgatcctga gctggtgggg gaggtgctca acaccatccg tcagctggcg caggaaaaac
    14341 gcaccatggt gatcgtgacc catgaaatga gtttcgcccg cgacgtagcc gatcgggcga
    14401 tatttatgga tcagggacgc attgtcgaac aaggcgaggc aaaagcgttg ttcgcttcgc
    14461 cccagcagcc gcgtacccgt cagttccttg aaaaattcct gatgcagtaa agcttgtgct
    14521 ggcgcggcgg ctcagcttcg cgggagccgc cgcgtttagc ccactctcgc ggcggggtaa
    14581 cgcccccgcg acacgtcttt gcgctattga ctcccacggc cgtatacacc gcttcccatc
    14641 gcccttggca gggtgtagaa catgatggga gaaaaacgct atgtttctgt gcggcgagcg
    14701 ggaaaatggc aagccttcag actaataaat gcgacagcta cgatatttta tacatataaa
    14761 taagatttat gtgttagttt tctgtattta taataatgat tatcaatcag gagttatttg
    14821 cacagctatg agggacaatg attttttcag ctggcggcgg gatatgctgc accaatttca
    14881 gtccatggcc accggcgagg aggtttataa tctcctgcaa cgtgaaaccg aagcgctgga
    14941 atatgattac tacacgcttt gtgtgcgcca cccggtgcct ttcacccgcc cccgcgttac
    15001 gttccagtcg acttaccccc gcgcatggat gtcgcactat caggcagaaa attatttcgc
    15061 gatagatcct gtgttacggc cggagaattt tatgcgtggc catctgccat ggaacgacag
    15121 cctgtttcgt gatgcgccgg cactgtggga cggggcgcgt gaccatggtc tgcaaaaggg
    15181 cgtgacgcag tgcctgacgt tgccaaacca tgctcaggga tttctctctg tctccgcgaa
    15241 caatcgtctg ccgggcggtt accctgaaga tgagcttgag ctgcgtctgc gaacgctgac
    15301 tgaactaagc ttgctgacgc tgctgcgtct ggaagatgag atggtgatgc cgccggagat
    15361 gaagttcagc cgccgcgaac tggaaatcct caaatggacg gcggaaggaa agacttcggc
    15421 ggaggtggcg atgattctct cgatttcgga aaatacggtg aatttccatc agaagaatat
    15481 gcagcggaaa tttaatgcgc cgaataaaac gcaaattgcc tgctacgccg tggcgactgg
    15541 gctaatctga atgcgcctgc cgttctgcgt gtcagacgtg ataccggctg tcagtgatac
    15601 tttcagccgg cacaggatta ctgccgatag gcttgtttaa tctgcttaac ggtgctggag
    15661 aatacggcgg cctgagcctc atcttccatc tgtgaaatct gcttttccat tttaataatc
    15721 acgcgccccg catccgcctg gcccatcgcc tgcagcatca gcgtaatcat cgctttcagg
    15781 caggagactt cctgcgccag ttcctgctta ttttctgcag tggaaaaatc tggtgtgctc
    15841 atcgatatcc tcgtttactc gctgcgctat tgcgctctac tcaatgtgaa ggccgcgcag
    15901 tataccacaa gcgacagaaa aaaaaggtgt gcttaatttc tgttctctca tctgagctgt
    15961 gaatgttttg atgcttcgga taatacgtaa tagccgtcgg caagccaata atttcccccc
    16021 atctatttag ctcgttaata attgttacat attttgcttc gtatttatgc gctacgtaat
    16081 ctgttgtgtt ttttgtgcct tctgtatgag tattgttaaa aaataagagc cgggcaactg
    16141 actgttctca atgactttcc acttagtgtg cacagacatt gccataaatg agagccaaat
    16201 cgaggcgagg gcattttttt gccttttaaa atagcaataa aacccggtaa tatgtgggag
    16261 ataaagtatc agtagcgtta tccctcattc tggagattat tcctttgatc aacgttcttc
    16321 ttg
//
