LOCUS       NZ_CP072712            17300 bp    DNA     circular CON 14-MAY-2024
DEFINITION  Enterococcus faecium strain VB3378 plasmid pVB3378_p5, complete
            sequence.
ACCESSION   NZ_CP072712
VERSION     NZ_CP072712.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN18533778
            Assembly: GCF_017898025.1
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17300)
  AUTHORS   Balaji,V., Yamuna,B. and Monisha,P.
  TITLE     Complete genome of Vancomycin Resistant Enterococcus faecium_VB3378
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 17300)
  AUTHORS   Balaji,V., Yamuna,B. and Monisha,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-MAR-2021) Clinical Microbiology, Christian Medical
            College, Ida Scudder Road, Vellore, Tamil Nadu 632004, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2021
            Assembly Method                   :: UNICYCLER v. v0.4.8
            Assembly Name                     :: VB3378
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 93.4x
            Sequencing Technology :: Illumina HiSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_017898025.1-RS_2024_05_14
            Annotation Date                   :: 05/14/2024 02:51:17
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,196
            CDSs (total)                      :: 3,103
            Genes (coding)                    :: 2,982
            CDSs (with protein)               :: 2,982
            Genes (RNA)                       :: 93
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 121
            CDSs (without protein)            :: 121
            Pseudo Genes (ambiguous residues) :: 0 of 121
            Pseudo Genes (frameshifted)       :: 40 of 121
            Pseudo Genes (incomplete)         :: 73 of 121
            Pseudo Genes (internal stop)      :: 28 of 121
            Pseudo Genes (multiple problems)  :: 17 of 121
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP072712.1.
            Bacteria and source DNA available from Christian medical college.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..17300
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /strain="VB3378"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /plasmid="pVB3378_p5"
                     /geo_loc_name="India"
                     /lat_lon="12.9165 N 79.1325 E"
                     /collection_date="2019"
                     /collected_by="Christian medical college"
     gene            complement(<2..1447)
                     /locus_tag="J7155_RS15475"
                     /old_locus_tag="J7155_15450"
                     /pseudo=""
     CDS             complement(<2..1447)
                     /locus_tag="J7155_RS15475"
                     /old_locus_tag="J7155_15450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305144.1"
                     /GO_function="GO:0015666 - restriction
                     endodeoxyribonuclease activity [Evidence IEA]; GO:0009007 -
                     site-specific DNA-methyltransferase (adenine-specific)
                     activity [Evidence IEA]"
                     /GO_process="GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit M"
                     /name="type I restriction-modification system subunit M"
     gene            complement(1785..3260)
                     /locus_tag="J7155_RS15480"
                     /old_locus_tag="J7155_15455"
     CDS             complement(1785..3260)
                     /locus_tag="J7155_RS15480"
                     /old_locus_tag="J7155_15455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="WP_000443455.1"
                     /translation="MESFVSLNLTNNTSKKNQPKDIKDIVDTRMYKERDDLNYTLIINK
                     DGNYSWRPLVLLHPILYVDLVNCLTKEDHWEELKKRFSEFKKDKNINCYSIPVEASKGS
                     KRTDLGETILNWWEYFEQKSLAQNIKYQYCMFTDIADCYPSIYTHSITWAMYGKEKVKN
                     DENKCSGSLGDKIDKKISGMQHNQTNGIPQGSVLMDFVAEIVLGYVDLRLSKELKKLEN
                     LKDYKVLRYRDDYRIFSNNRNDLEQIMKVLSEVLYDLNFKLNSSKTKLSDDIIIDSIKK
                     DKLYWEEIKASIRMNATNLDGDREIRYSINLQKHLLEIKKLADKHPNSGQLKKALSEFN
                     KERIIKITSKPNDLLPLIGILVDIMINNPGSLPQCVLIIGQLLNFENESKAREIVEMII
                     NKYALKPNTEFMMIWFQRLTTIFGEMFDSVLSSEFVSKIKDPVSNQMFSVDWLNEDAKK
                     SFYEGTIKDEEKYIKMSKKIYITEFDDFNDYPF"
                     /name="RNA-directed DNA polymerase"
     gene            complement(3238..4191)
                     /locus_tag="J7155_RS15485"
                     /old_locus_tag="J7155_15460"
     CDS             complement(3238..4191)
                     /locus_tag="J7155_RS15485"
                     /old_locus_tag="J7155_15460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="WP_000222572.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNFL
                     KCGGTALEYFEQYKENKRRCGRTEIIFPAEEKEYIEKRSTEGWTPDVIIGRAERTFSCS
                     VSTLYRRFKTGEFNVLHLPMQGKRKPNGYKEKRGKQAFKRNISERKKDYVVFEEEFGHL
                     EGDTIVGIHHKSAVITLVERLSKAIIALKPEGRKAVDIENSINEWLQSVPKNLFKSITF
                     DCGKEFSNWKSISNTNDIDIYFADPGTPSQRGLNEHSNGLLRKDGLPKEMEFNQVNQGF
                     ISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA"
                     /name="IS30 family transposase"
     gene            4685..5857
                     /locus_tag="J7155_RS15490"
                     /old_locus_tag="J7155_15465"
     CDS             4685..5857
                     /locus_tag="J7155_RS15490"
                     /old_locus_tag="J7155_15465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="WP_000195429.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTEY
                     IQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKALM
                     ASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKNYPY
                     LMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEYLKER
                     GLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFREAVKGI
                     FKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRLKSTNLI
                     ERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
                     /name="IS256-like element IS256 family transposase"
     gene            6166..6729
                     /locus_tag="J7155_RS15495"
                     /old_locus_tag="J7155_15470"
     CDS             6166..6729
                     /locus_tag="J7155_RS15495"
                     /old_locus_tag="J7155_15470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000017403.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAVR
                     PQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTPHG
                     RLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQVYS
                     VKEITEMTGISKATLYRYLKDNRE"
                     /name="recombinase family protein"
     gene            complement(7008..7295)
                     /locus_tag="J7155_RS15500"
                     /old_locus_tag="J7155_15475"
     CDS             complement(7008..7295)
                     /locus_tag="J7155_RS15500"
                     /old_locus_tag="J7155_15475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_000312842.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQK
                     TGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPNLLCGTHENFYEQLKKIR"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(7285..7614)
                     /locus_tag="J7155_RS15505"
                     /old_locus_tag="J7155_15480"
     CDS             complement(7285..7614)
                     /locus_tag="J7155_RS15505"
                     /old_locus_tag="J7155_15480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000629052.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEPK
                     KEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEELA
                     AEIGL"
                     /name="hypothetical protein"
     gene            7919..8248
                     /locus_tag="J7155_RS15510"
                     /old_locus_tag="J7155_15485"
     CDS             7919..8248
                     /locus_tag="J7155_RS15510"
                     /old_locus_tag="J7155_15485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000754864.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIKI
                     FYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDILS
                     AIRVF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            complement(8535..9020)
                     /gene="vanZ-A"
                     /locus_tag="J7155_RS15515"
                     /old_locus_tag="J7155_15490"
     ARG             complement(8539..9020)
                     /name="vanZ-A"
                     /gene="vanZ-A"
                     /gene_name="glycopeptide resistance protein VanZ-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(9173..10084)
                     /gene="vanY"
                     /locus_tag="J7155_RS15520"
                     /old_locus_tag="J7155_15495"
     CDS             complement(9173..10084)
                     /gene="vanY"
                     /locus_tag="J7155_RS15520"
                     /old_locus_tag="J7155_15495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="WP_000732308.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHLE
                     NSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLLDS
                     NIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGYSEH
                     NSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIRYVGL
                     PHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNLRYEIS
                     GNNIDGVIVTVFPGSTHTNSRR"
                     /name="vanY"
     gene            complement(10512..11120)
                     /locus_tag="J7155_RS15525"
                     /old_locus_tag="J7155_15500"
     CDS             complement(10512..11120)
                     /locus_tag="J7155_RS15525"
                     /old_locus_tag="J7155_15500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="WP_000402348.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTYE
                     LAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRTEM
                     ISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEAQNR
                     RRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
                     /name="D-Ala-D-Ala dipeptidase VanX-A"
     ARG             complement(11127..12175)
                     /name="vanA"
                     /gene="vanA"
                     /gene_name="glycopeptide resistance gene cluster; Van
                     ligase"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="99.71"
                     /coverage="101.75"
     ARG             complement(11130..12157)
                     /name="vanA"
                     /gene="vanA"
                     /gene_name="D-alanine--(R)-lactate ligase VanA"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="99.71"
                     /coverage="100.0"
     gene            complement(12150..13118)
                     /locus_tag="J7155_RS15535"
                     /old_locus_tag="J7155_15510"
     CDS             complement(12150..13118)
                     /locus_tag="J7155_RS15535"
                     /old_locus_tag="J7155_15510"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="WP_001059542.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKSA
                     PFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAYSP
                     DSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKAVIE
                     RLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQRMKQ
                     GAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQFLLKL
                     QRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
                     /name="D-lactate dehydrogenase VanH-A"
     gene            13450..14742
                     /locus_tag="J7155_RS15540"
                     /old_locus_tag="J7155_15515"
     CDS             13450..14742
                     /locus_tag="J7155_RS15540"
                     /old_locus_tag="J7155_15515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1251 family transposase"
                     /protein_id="WP_000122610.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIYT
                     AQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADTSV
                     AKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTPLPK
                     VLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREAVEWI
                     VIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQKHYQLG
                     KQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQLYQDFL
                     YAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPLECLNNHI
                     KVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
                     /name="ISL3-like element IS1251 family transposase"
     gene            complement(14840..15994)
                     /locus_tag="J7155_RS15545"
                     /old_locus_tag="J7155_15520"
     CDS             complement(14840..15994)
                     /locus_tag="J7155_RS15545"
                     /old_locus_tag="J7155_15520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-A"
                     /protein_id="WP_002305818.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGKL
                     GDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKYFD
                     EINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVMYLA
                     HDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRYNLQT
                     ITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFNNILKN
                     AAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSSDTGGAG
                     LGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
                     /name="vancomycin resistance histidine kinase VanS-A"
     gene            complement(15972..16667)
                     /gene="vanR-A"
                     /locus_tag="J7155_RS15550"
                     /old_locus_tag="J7155_15525"
     ARG             complement(15976..16667)
                     /name="vanR-A"
                     /gene="vanR-A"
                     /gene_name="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(16881..>17300)
                     /locus_tag="J7155_RS15555"
                     /old_locus_tag="J7155_15530"
                     /pseudo=""
     CDS             complement(16881..>17300)
                     /locus_tag="J7155_RS15555"
                     /old_locus_tag="J7155_15530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /name="recombinase family protein"
     ARG             complement(12154..13118)
                     /name="vanH-A"
                     /gene="vanH-A"
                     /gene_name="D-lactate dehydrogenase VanH-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(14844..15994)
                     /name="vanS-A"
                     /gene="vanS-A"
                     /gene_name="vancomycin resistance histidine kinase VanS-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(9177..10084)
                     /name="vanY-A"
                     /gene="vanY-A"
                     /gene_name="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="99.67"
                     /coverage="100.0"
     ARG             complement(10516..11120)
                     /name="vanX-A"
                     /gene="vanX-A"
                     /gene_name="D-Ala-D-Ala dipeptidase VanX-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(12151..13118)
                     /name="vanH gene in vanA cluster"
                     /gene="vanH gene in vanA cluster"
                     /gene_name="vanH; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(15973..16667)
                     /name="vanR gene in vanA cluster"
                     /gene="vanR gene in vanA cluster"
                     /gene_name="glycopeptide resistance gene cluster; vanR"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(9174..10084)
                     /name="vanY gene in vanA cluster"
                     /gene="vanY gene in vanA cluster"
                     /gene_name="vanY; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="99.67"
                     /coverage="100.0"
     ARG             complement(8536..9020)
                     /name="vanZ gene in vanA cluster"
                     /gene="vanZ gene in vanA cluster"
                     /gene_name="vanZ; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(14841..15995)
                     /name="vanS gene in vanA cluster"
                     /gene="vanS gene in vanA cluster"
                     /gene_name="vanS; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="100.0"
                     /coverage="94.79"
     ARG             complement(10513..11120)
                     /name="vanX gene in vanA cluster"
                     /gene="vanX gene in vanA cluster"
                     /gene_name="vanX; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="99.5"
                     /coverage="100.0"
ORIGIN
        1 cttcttcttc ttcaaaggta tccacgtaac ggggaatgtt taagttgtaa tcattctcca
       61 caatttcatc aaattctgcg acataagcat acttgtcttt aattgtacgg gttttatagg
      121 cctctaaaat agcgtcaata tggtaatctc gtagcgtatt ttgcgttttt attttttcaa
      181 aatcttgtga cgcatcaata aagagcacat cttttttcgc acggtctttc ttcaagataa
      241 ttacggtcgt tggaatggac gtattaaaga agatgttagc aggtaagcca atgacggtgt
      301 caatggcacc attttctaac aaggctttgc gtatcttccc ttctgcgccc cctctaaaga
      361 gcaccccatg tggcaaaaca atggccatga cgcccgtatc tttcaaatga tagtagccat
      421 gtaataagaa agcaaagtcc gcttttgatt taggggctaa tacgccatag gcagagaagc
      481 gtgggtcatc taagaagcct ttatcagccg accattttgc agaatacggt gggttcatga
      541 gcaccccatc gaagttcgtt ggctcttctg ttggccagtc ttgatccaag gtatccgcat
      601 tatgcaagtg ttggttggca atgggaaccc catgcaaaat catgttcata cgcgccaaat
      661 tataggtaga cgtattcaac tcttgtccga aataagaaat ggttcccggt tgatgggaat
      721 attttttagc gttcaaaagt aacgagcccg aacccatggt cgcgtcgtaa acagaaaagc
      781 cttttttatc ttcttttcct tgtaaaacaa tttgtgtcat caattttgcg accggttgtg
      841 gggtatagaa ttcaccggct tttttaccgg attcagatgc gaattggcca attaagtact
      901 cataggcatc gcctaagaca tcgccagcat gccccgccat gtttaaccct tctaattctt
      961 tcataacatc tgcgatggtt ttattttgtt tttgtggggt tgaccccagt tttttagaat
     1021 acagatcaat gtcttcaaat aagttctcaa agttttcgct ggattgttca atgtcacgga
     1081 aaccttgtac caggtcttct aattgaaaag atccatcatg aatggctgcc acttgcgcgg
     1141 taaaggtcaa tgcgggtgcg atggtatatg aaaactcatc ttttagttca tacaagagat
     1201 catcctttat atctgcatct ttaaatgctt caacgtaaag gtcttgtgct ttatttaggt
     1261 cgtccgtttc ttcctccaat agaacggaga cataccgcag catgttgtcg gataagtatt
     1321 tataaaagac caagcctagt aaatagctct tgtattcatt agcgtccatt tttgaacgca
     1381 ggatatctgc ggaattccac agtgcctgat ataagctttt tgaatttttt tcgatttgtt
     1441 ctgtcattgg ttattttcct cattcgtgtt gtatttttta taaatcagtt ttttaaaaaa
     1501 ttagttacta tttgaacttg ttttttcacc atatgtattt taatgaaatg gataagctac
     1561 atttgcttag acaattcatg tcttacttaa ttcttattat aacaaaccta tttcaccttt
     1621 ttcgatacat taaataataa gtaacttaaa ataaggttcg aataaccttg ttaaatagtg
     1681 gttttcttat cttatagtat agaaatcaag agattacttc cgatataaca tttttttaaa
     1741 aaaattagat tgtaatgttt tttatattca ttctaaattt tcacttaaaa aggataatca
     1801 ttaaaatcat caaattcagt aatatatatt ttcttactca ttttaatata tttctcttcg
     1861 tctttaatgg tcccttcata aaaagatttc ttagcatctt catttagcca gtctacagaa
     1921 aacatctgat tagagacagg atctttgatt ttagatacaa attcggatga taaaacacta
     1981 tcaaacattt ctccaaaaat ggtggtcaat ctttgaaacc atatcatcat aaattcagta
     2041 tttggcttta aagcatattt gtttataatc atttcaacta tttctctagc cttactctca
     2101 ttttcgaaat ttaataactg ccctataatt aagacacact gcggcaaaga acccgggtta
     2161 tttatcatga tatctaccag gataccaata agtggtaaaa gatcgttcgg ctttgaagtg
     2221 attttaataa tgcgttcttt attaaactca gaaagtgctt ttttcaattg gcctgaatta
     2281 ggatgcttat ctgctaactt ttttatttcc aataaatgtt tttgtaaatt tatactataa
     2341 cgaatttctc tatcaccatc taagtttgtg gcattcattc ttatacttgc cttaatttct
     2401 tcccaataga gcttatcttt tttgatagaa tctatgataa tatcatctga taattttgtt
     2461 ttactagaat ttaacttaaa atttaaatca tataagactt ctgataacac tttcataatt
     2521 tgttccaaat cattacgatt atttgaaaat attctataat catctctata tctgagtact
     2581 ttgtaatctt ttaaattttc taattttttt aattctttcg ataatctcaa atcaacatac
     2641 cctagaacga tctctgctac aaaatccata agaacggaac cctgagggat accatttgtt
     2701 tgattgtgtt gcattccaga tattttttta tctattttat cgccaagtga gcccgaacac
     2761 ttattttcat catttttaac tttttcttta ccatacatgg cccatgttat agagtgagta
     2821 taaattgatg gataacaatc agcgatgtca gtaaacatgc aatattggta tttaatattc
     2881 tgagctaagc ttttttgttc aaaatattcc caccagttta gtattgtttc accaagatct
     2941 gtcctttttg aacctttgga agcttcaaca ggtatagaat aacagttaat atttttatct
     3001 tttttaaatt cactaaacct cttttttaac tcctcccaat ggtcttcttt agtgagacaa
     3061 ttaaccaaat ctacatatag aataggatgt agtagaacga gaggacgcca tgaatagttt
     3121 ccatctttat tgataataag cgtatagttt aagtcatcac gttctttata cattcgtgta
     3181 tctacaatat cttttatatc tttcggttgg tttttttttg aagtattatt tgtcaaatta
     3241 agcgagacaa aactttccat ttacgtaact caaaaaaact tctaatggtg tttggtaatt
     3301 tagtgatttt ctagggatat ggtttctttt ggacgcaacg gatgagatga atccttgatt
     3361 gacttggttg aattccattt cttttggtag tccatctttt cggaggagtc cgtttgaatg
     3421 ttcatttaat ccccgttggg aaggcgttcc tgggtctgcg aaataaatat caatatcatt
     3481 cgtattacta atacttttcc aattagagaa ttcttttcca caatcaaagg taattgattt
     3541 gaaaagattt ttgggtacgg attgaagcca ttcattaatc gaattttcaa tatcaactgc
     3601 cttacggcct tctggtttca aggcgataat ggcttttgaa agtcgctcaa cgagtgtgat
     3661 gacggcactt ttatggtgga tgccgacaat cgtatcaccc tctaaatgtc caaattcttc
     3721 ttcgaaaacg acataatctt ttttacgttc agaaatattt cttttgaatg cctgttttcc
     3781 acgtttttcc ttataaccat ttggttttcg ttttccttgc atcggtaaat gtaaaacatt
     3841 gaattctccc gtcttaaacc ggcgatagag ggtacttact gaacaagaga aggttcgctc
     3901 tgcacggcca ataatgacgt ctggggtcca accttcagtt gatctttttt caatgtattc
     3961 tttttcctca gcaggaaaaa tgatttcggt tctcccacaa cgtcgcttat tttctttgta
     4021 ttgttcaaag tattcaagtg ctgttccacc acatttgaga aagttataga cattgtaaat
     4081 tgtttggcgt ccacgtttaa gctgcttcgc aacgatagca accggagttt cttgatgaaa
     4141 atatgcttct atcattacaa gctcgtttgg tgtaagatgg gtataagtca tttatgttca
     4201 ctctccttgt atgctttagc gggtattaca atttgagtgt aacataaatg gcttttttat
     4261 ttgtctcgct taattataca aacggcgaag ttaaaacttt tttagcagat tttaaagttt
     4321 cgtcaaaact aatatattct ggtagctgag cattcaaata gctttcagac ttcagaagaa
     4381 aattacgagc atttttatag tccatctcta ataaagttat tcttttttta tccaatacat
     4441 tcagctcaat tccttataat attctattcc ttagtatctc aacattattt actttataaa
     4501 acgaataaat tttgtagttc taattcaaat attgcatgtt atatctaata tgggagcatt
     4561 ttataatttt cattgtgata aacgataaag tccgtataat tgtgtaaaag taaaaaggcc
     4621 atataacagt ccttttacgg tacaatgttt ttaacgacaa aaacataccc aggaggactt
     4681 ttacatgacc caagtacatt ttacactgaa aagcgaagag attcaaagca ttattgaata
     4741 ttctgtaaag gatgacgttt ctaaaaatat tttaacaacg gtatttaatc aactaatgga
     4801 aaatcaacga acagaatata ttcaagcaaa agaatatgaa cgaacagaaa accgacaaag
     4861 tcaacgaaat ggctattatg agcgcagctt tacgacacgt gtaggcacgc tagaattaaa
     4921 agtacccaga acacgtgatg gccatttttc acccacagtg tttgaacgtt atcaacgaaa
     4981 cgaaaaagcc ctcatggctt caatgttgga aatgtatgta tcaggcgttt caactcgtaa
     5041 agtatcaaaa attgtggaag aactttgtgg taaatccgtc tctaagtcct tcgtttctag
     5101 cttaacagaa cagctagaac ctatggttaa cgagtggcag aatcgtttat tatcagaaaa
     5161 aaattatcct tacttaatga ccgatgtact ctatataaaa gtacgagaag aaaatcgagt
     5221 actctcaaaa agctgtcata tagcgattgg aataaccaaa gatggcgacc gtgaaattat
     5281 cggcttcatg attcaaagtg gcgaaagcga agagacctgg acaacatttt ttgaatacct
     5341 aaaagaacgc ggtttacaag gtacggaact cgttatttct gatgcgcaca aaggattagt
     5401 ctctgccatt agaaaatcct tcaccaacgt aagttggcaa agatgccaag ttcacttcct
     5461 aagaaatatc tttaccacca ttcctaaaaa aaattcaaaa tctttcagag aagctgttaa
     5521 aggaattttt aagttcacag atattaactt agcgcgtgag gctaaaaatc gattgattca
     5581 tgattatatc gatcaaccaa aatattcaaa agcttgcgca tcattggatg atggattcga
     5641 agacgccttt caatataccg tacaaggaaa ttcccacaat cgactaaaga gtaccaatct
     5701 aattgaacga ctgaatcaag aagtacgcag aagagaaaag attattcgca tcttccccaa
     5761 tcaaacatca gccaatcgct taattggagc cgttcttatg gacctgcatg atgaatggat
     5821 ttattcttca agaaaataca tcaattttga taagtagaaa ttgtaaaaac attgtatagc
     5881 attttacaca ggagtctgga cttgacttga taaactcgtt attaacttta ggatacacta
     5941 gttaggatta aattaggtat ctagaaattt acttaagatt tttttgttta tttcgtatac
     6001 acactcgtat caaaaacaat cgattatgag acaaaatgaa atgacctctt ttattaaata
     6061 aaagaggtca tattttgtat cataacttgt tgcattaact atgtatctat aactcccttt
     6121 tatgatacaa tcaagccaga attaaagtac gaaaggaaga aaagcatgag tggatacatt
     6181 tatggttatg cccgagtgag tacacgttca caagaactaa atcgtcaatt agacttactc
     6241 aatgaacaaa attgtaatga aatcctaact gagaaaatga cgggaaccaa agcggttcgt
     6301 ccccaactaa atcgtttaaa agataaaatt cgtccgggag atacggtaat tgtagaaagt
     6361 ttttctcgat tgggtcgtag tacaaaggat ttgattgacc ttgttaccta ttttgaagaa
     6421 caccatgtta agctggtgag cttgaaagaa aacttcgata ccagcacgcc tcacggacgc
     6481 ttaatgatga ctgtcttcca agcatttagt cagttcgaac gtgatttaat tgttgaacgt
     6541 accaaagaag gtttgaaaag tgcacgtgcg agaggtcgta aaggtggccg tccacgagtg
     6601 aaccagaaag atgttgatcg agcagtaaaa ttgtataaaa gtcaggttta tagcgtaaaa
     6661 gaaattacgg aaatgactgg tattagcaag gcaacactct accgctactt aaaagacaat
     6721 agggaataat ctattttaat ctttaggaat ctataatatt tatgggagaa ttagagtgat
     6781 ttttttatta ttactaaaaa acaatataaa ataacgcatt ttaagccctc tttgtgcata
     6841 aggatgaagc ttttaatttg aaagaggctt aaaatgcgtt ttaatttttt ctatttttca
     6901 taaatatata ggttagtggt ttaaaattat agggtattac aactctcagc tgttaaaaat
     6961 tatcttttaa agtgtcgtct atcctctcaa gttgaaacat tgggttctta cctaatcttt
     7021 tttaattgtt cataaaaatt ttcatgcgtt ccacatagta agttaggtat cactgcatta
     7081 tctttaattt catatgcaac gcgatatgtc gtacctgcat acttgaatcc aatagcccaa
     7141 attcctgata aatcacccgt tttttgttct cccgaatgag gacgaactgc tatctcatca
     7201 taaattatcg ttaaaaattg ttcttttaat gttttctctt ttaatttttt tagatacttt
     7261 attacgtgtt tagaaggtag aatctcataa gccaatttct gctgccaact cctcttttgt
     7321 catcggttta gaatttgcaa cagtatcttc agcaatagat ttaaatgcag aagttaacgc
     7381 attttttcta tttctaaatt cttttaagat ctcttgtttg ctataacctt ctgaaagaat
     7441 atcagccaaa atatcttcac taaaatcaaa aaattctttt ttaggctcta caaactcata
     7501 aaggatacca ttctctacaa gcttagcttc tacttcaaca ccattgggca catcgaattc
     7561 tttagggacc gttaacataa tagaatttcc ttgttttctt gtttttgtaa tcatattatt
     7621 tcctccatta ttttacattt cgtaattact tagtaattac attgtacgct atttttagta
     7681 gaaatacaaa ataataaaac tcctttagaa caattttcaa aggagtttta tttgattagg
     7741 aaattatgta gaataataat atgtttttaa cttggaatca aaaacgcact tgcaagtaag
     7801 tttacttcaa tacatgaaat tgcttataat agtgtattgg aattaaggta gattgacaaa
     7861 agagtgatca aataggtata cttcattcaa ataatcgttt gaatgtgagg tgagatgaat
     7921 gaaaaaagtt tgccaagtga ctgtcgtaca taaagaaaaa gtaaatggaa taaaaaataa
     7981 attggatcaa aaagattttt caaacttact tgtgttaggg aaatgtttca gcgatttttc
     8041 tagaattaaa attttctatg ctttagaaac ctataaggaa atgtgcgtct gtgatttagc
     8101 agaaatactt actgctagtg tcgctacaac gtcacaccat ttacgttttt taaaaaaaca
     8161 tggaatggca aaatcacgtc aagatggaaa agtagtttat tactctttag cgaatgaaga
     8221 catcctttcc gctattcgtg ttttttaaag ttatcagaaa atctatctat gaaatcttag
     8281 tttgggggta ccgtcaggaa aatgcggatt tacaacgtta aggaaattta ttaaagagac
     8341 caattcctca gcactaaaat tgataattgg gctttctttg ttactatagt gttaggtaag
     8401 ctttttactt tatcaccggt tttcccctca cttcacacct acgggcgagt ttccccacat
     8461 cccgttttcc atctaatcca attcattcaa tatctttatg tgtatgaaag atcagattgc
     8521 ttgatttaga catcttacac gtaatttatt cttaaatggg tacggtaaac gagcaataat
     8581 acgagcaaaa gtatacctac aaaaataata actctgtcta attttttttg attcatatgc
     8641 ttattgctta aaccatataa tttcagtcca agaaagcctc caacagtatt tgtaattaca
     8701 tctgttatgt ctgtcgctcc aatagcgaag ataaattgaa ttatttcaaa agtaagactt
     8761 aaaaccagta caaaagcaaa cttaggtaaa aatccgattt ctttaaaatt gacattcaaa
     8821 agcaagccaa atggaataaa gattataaca ttatctatca tctctctgaa attcccagta
     8881 gcagtaaatg gagtcaagtt aagacttctt tgatgataat taaatactga taaaatattg
     8941 tattgtaatt tgaataacac taaccagatt agtgtcacta aatataaagc tagcaatcct
     9001 ctagataata tttttcccaa tataatttcc tctaattctt ttgtttaagt tgtatcatta
     9061 gtatagcaat gtcctagtta acgtgggttt taaattaaaa agctaacgtt accccaaaag
     9121 tgctagtaca ataatgctgt tcattaattt cgttggtttc attccgccat ccttacctcc
     9181 ttgaattagt atgtgttgat ccgggaaaca ctgtcacaat tacaccgtct atattgtttc
     9241 ctgatatctc ataacgaaga ttagtcggca catgaatggt ggtattttta gtaacaggat
     9301 aataaaagat ctcatatttt tccccattta cactaacaga aatggttttt tcttctttta
     9361 ggtaatccat atattcctcg agaacgaaat tcttttcttt cataatcgca ctatgtggta
     9421 aaccaacata gcgaatatgc catagttcat attgaattcc tgttaactct gttttgtcct
     9481 ctggataacg taaaatgaac ccgtatttcc aagcattttc ttctatccac tttccttcag
     9541 gggctcgttc cattttcgtc aagcttgatc ctacatctag tgataaacct gaattatgct
     9601 cactataacc tgctggtaag gcatactcag cccccatttc ttggtaaagc acactttgct
     9661 catcaaagtc tcgatagcca ctattaataa taaaatgact aacgccaccc tttacagcat
     9721 cattgaccat ctctgaaaat ttttgtgcta tttcttttga catataaata ttactatcaa
     9781 gcaacccgta tccatttatt aattcgtcat gtttagataa attcacgata tctgacttca
     9841 cactttcttg gcgaacagga tatttactat tgattaatag cagatttcct tgataaacct
     9901 gttcttctgt aattgttttc tcttgggtat tttcagaagt cccactattt tctaaatgtt
     9961 ctttgggatt ttgatcataa ttttgaaatt cgactttttc ctgagaaaac agtgcttcat
    10021 taacgtagtc ataacctaag tatattaaga ataacaataa caataaaaaa aacaacttct
    10081 tcattttcag tctcctcctt aactatatag ttggaagtat gaaatatttc tagaatcttc
    10141 cccttaaacg gcacaatctc gtttgagatt gtgccgtttt gccccgtaaa ttacagtcaa
    10201 ttatttcgcc ctactggatt tactattatc accaatgtag atgaattttc ataagtgata
    10261 cccatgctga atttaacgag gctgaactgc ctgttgacaa tgggcggtgt gaaataccac
    10321 ccctctatgc gatcagtctt attatcaggc tatcttgccg cagcgcacgc agataatgac
    10381 cgcaatatcg ctctgcctta catcttcaat actatctact atatataaat tccctaagaa
    10441 ccagttacat acgtcgggtt tcctgccgaa agagttagct tatatagttt gtccgtgcaa
    10501 cggttaaaag tttatttaac ggggaaatca aaatagctat tggggtatgg ttcgtctctt
    10561 aatacatagt gccaccattc gaggctatat gcttcaaacc cactgttttc catgatggag
    10621 cgcaaacgtc tgcgattttg cgcttcattg catgatattc catttgccgc atgatgagag
    10681 cgttcatcca taaaatcaaa tcggctcccc attggtacaa gctcacccgt gtctaatcga
    10741 taaagcgtaa gatcaatggc actgccgcgg ctatggcttg attttgaagc cacgtatcct
    10801 tttgaaatca tctcagttcg gtcaatattg ggataataac tttcctttgt caggttattt
    10861 tccggctgtg cagcccattg cataaaacag tttacagcac gattaggacg gtaaccgtcc
    10921 catagaagca atccgtaccc ttgggtagca gccagttctt ttgccttcaa aagcgattca
    10981 gccaactcgt atgtccctac aatgcgattt acttcataac cgtcaaccgg ttttccggtg
    11041 aaattatccc aagtggcata tttagcgtcc caacgaacac cgtgtactat ttcatctaaa
    11101 aaagtaaatc ctatttccat gcttatcacc cctttaacgc taatacgatc aagcggtcaa
    11161 tcagttcggg aagtgcaata cctgcagcgg ccatcatacg gggataacga ctgtatgacg
    11221 tgaaaccggg cagagtattg acttcgttca gtacaatgcg gccgttatct tgtaaaaaca
    11281 tatccacacg ggctagacct ctacagccga gcgctttata tatttttttt gccgtttcct
    11341 gtatccgtcc tcgctcctct gctgaaaggt ctgcgggaac ggttataact gcgttttcag
    11401 agcctttttc cggctcgact tcctgatgaa tacgaaagat tccgtactgc agcctgattt
    11461 ggtccacctc gccaacagct aacgcggcac tgtttcccaa taccgcacaa ccgacctcac
    11521 agcccgaaac agcctgctca attaagattt tgctgtcata ttgtcttgcc gattcaattg
    11581 cgtagtccaa ttcgtccgcg ctattgactt ttttcacacc gaaggatgag cctgaacgcg
    11641 ccggcttaac aaaaacagga taggtaaacg tagctgccac cggcctatca tctttattaa
    11701 taacccaaaa ggcgggagta gctatcccag catttttcgc aacgatgtat gtcaacgatt
    11761 tgtccataca aattgctgag ctttgaatat cgcagcctac aaaagggata ccggacaatt
    11821 caaacagacc ttgtatggat ccatcttcac ctgacttgcc atgcaaagct gaaaatgcta
    11881 catcaacatg gttgatttca tattcatggt tctttttaac aagtaatccg tgcatttttt
    11941 tatccggcga gagtacagct gaatagcaat tgtcgttttc ccattccgcg caaggttttt
    12001 cgcacatttt ccatacacca gatttcgtaa ttccaatgta taacggctcg tatttttctt
    12061 tattaatgtt agcggctatc tctattgcag attttaccga tacgtcatgc tcctctgagc
    12121 aacccccaaa cagtattgca acttttattc tattcatgct cctgtctcct ttcaaaatcc
    12181 aaacagtttt taatggtttt ttcaacggta tcacgcaacg cttgctcggt ataataggcc
    12241 gtatgcggtg tgattatcac gttaggcatt ctttgaagtt taagtaaaaa ttgattatca
    12301 attggttttt gggtgcaatc agagtagaaa aactcttcct ctccttccaa tacatccaat
    12361 gcggcaccgc ccagtttccc gttttctaat gctttaacca actcataggt atctacaagt
    12421 ggaccgcgcc cagtattgat aagaaatgct ccttgcttca ttctctgtat ttgttcgtgg
    12481 ctgataatat agtgcgtatc cgtattgagc ggcacatgaa gcgtaacgat atcgctattt
    12541 tgcagcaact catcaaacgg tacatagttt acctctatac ttcggctgcg actataagcc
    12601 aacactttac atccaaatcc tcgcagccgc tcaataaccg ctttgcctat ctggcccgtt
    12661 cccaccacac caactgtcat gtcgctgagt accttgccac ggtcgctgtc caacctgaaa
    12721 tcatgttttt ccacagagcg cacaatcgat tttacgttgc gtactgccat aagaattagc
    12781 atcatagtat aatcggcaac gctatccggc gagtacgcca cattgtcgac agtgatgccc
    12841 attctcttag cagcagttgt atctatatga ttgcagccga tgcttcgggt agaaatatat
    12901 ttcacaccgg ctctcttcag cgcaagaaga atagaggcgg aaatctctga tttatgtccc
    12961 acactgatac attgattgaa aggcgcggat ttggcgttgg attccgacac gttggcgtta
    13021 attatcgttg ccataacgcc aaagcgaggc gaaagagcat ggaatgcatc tgcctcatcc
    13081 tgctcacatc cataaacagt aatgccgatg ttattcataa ttaagaccaa ccctttctgt
    13141 gaaaggcacc aaataaaacg gggatgccaa tggtaatctt gtcaaatctt tctctgaaga
    13201 acgaaaacgg ctcgttctta cggtattaag tctaccgtgt aagaacgagc cgtttcttaa
    13261 tattaaattg ttaatttcct aagaaaaagt aaagataacc ttgagatttt cctaaaaaat
    13321 tatggctcta tactttttga tgttggtgga tgacaccagc atctttttta ttttccaaaa
    13381 catatagaaa agacaccttg aaatccttta gaattaattt ggcgaaccaa cccaaaagga
    13441 ggaatcaaga tgtcttacac tcaccttatc aaagaaacat tagatattct agacttatca
    13501 gttactttta acgaaaattg tctcacaaaa gaaaaataca aagggcaaat ctgtcatatt
    13561 tatcgtggaa acttgattta tacagcccaa gaatgcatcc actgtaaaca ccagattgct
    13621 tcagatattg tgcgttgggg tacaacaacc gtccggttgt taatgaacga tgtttctgaa
    13681 taccgtacct acctcgaatt gaaaaagcaa cgcttcaaat gcaaagcttg tcagcggacc
    13741 tttgtcgcag atacttctgt tgcgaaaaaa cattgtttca tcagtgagaa agtccgctgg
    13801 tctgtcgtga ctcgtctgaa aaaaaatacc tcaatgacag agatcgccgc tcagaaaaat
    13861 ctatcggtct cttctgttta ccgtattatg aagcgatttt atcgtccgtt gaatcctttt
    13921 cggacaccgt tacctaaggt actttgtttt gatgaattca aatcagttcg gggtgtttca
    13981 ggtgctatga gtttcatcat gatggatgga caaacacagc gcttattgga cattgtcgag
    14041 aaccgacaac tgcctttttt aaaacgttat tttagtcatt tttcacgaga aattcgtgaa
    14101 gcggtcgaat ggatcgtgat tgatatgtac gctccttatg tatcgctcgt taaaaagctg
    14161 tttccaaaag cacagctgat tattgaccgg tttcacatcg tccaacatat tggtcgtacc
    14221 tttcgcaatc atcgaatcaa agaaacgaac caactattaa aaagcaaaga acaaaaacac
    14281 tatcaattag gtaagcaatt aaaaagatac tggaaacttc ttcaaaaaga tgaacgcaag
    14341 cttgattata ctcgacgcct ttggcgacct ggcttcaaag ctcatttaac agagaccgat
    14401 attgtggatc gcttactgaa agggagccct gctttgcgtg taggctatca gttatatcaa
    14461 gactttcttt acgctgtaaa ggaacgagac tacgtatcgt ttgaagaact acttaccaat
    14521 aatatcatgc ttcccgaagg ctatcagacg accttgagaa cgttccagaa atttctgcca
    14581 caaatcaaaa atgctttaca acaaagttat tcaaatggcc cacttgaatg tctgaacaac
    14641 catatcaaag tgttaaaacg aaatgcatat ggctttcgta gcttttataa tttcaaattg
    14701 cgcatcatga ttcgtcatgg caacgcattg attttcaact aaaaaagatc aagaggaact
    14761 gatccacttg atctccaatt attctaagat ttctctttac caacatcatt tgacaaagag
    14821 ccaaaattat atacatctct taggacctcc ttttatcaac caagtctggc atcgctggaa
    14881 gctctaccct aaacgtcgta tagttatcat tgctttccgc gtaaatctgc cctccatgct
    14941 gaacaataat ttcttttgca atcgccaatc caagtcccgc gccacccgta tcggaagaac
    15001 gagcattgtc cagcctatag aacttttcaa atatggcagc tagcttatct tttgggatgc
    15061 ttccagtgtt cttgaattcg attgacacca catccccgga gaggcccgcg gtaatgtcaa
    15121 tgatgctgtt atcctcactg tatgcagcgg cgtttttcaa aatgttgtta aagactctcg
    15181 cgagtttatc agggtcgccg gacacggtca gatcctcggg ggcgtgaata accgcctgtt
    15241 ttccatgtgc ggaaagctga ggataaaatt catcggtcat ctgcaccagc atatagtata
    15301 ggtctatgtg cgtttttgtt agcgttatcg tttgtaggtt ataccgtgta atctcaaaaa
    15361 actcgtcgat tagctgttcg agtcgatacg ctttgtccaa cgtgatatgc acatactttg
    15421 ccttttgatc taccggcatg tctggagcct cgtcaagcag gctcaaataa ccgataatgg
    15481 atgtaagggg cgttttaata tcgtgcgcca agtacataac aacgtcattt tttctttgtt
    15541 cggccagctt tgcatcctgc tctcgctttt ccagagtccg ttttaatgtg ttgagctttt
    15601 gttccataac atccatttcc gcagaaagct caatttgttt atcttcgttc tgaataagta
    15661 catcaatgcc ggtatttatc tcgtcaaagt attttgcgaa ttttgaaagc atgacgcgac
    15721 atagaataag aatactaatg acaatcgcca cataaataaa gatatctata ttgttccgta
    15781 tggaatattg atataatttc atcgcgtcca ggtgatttaa gtcatatttg ttttccaaaa
    15841 tacttaagat ccaatcccca agtttccctc ggatcattga acgaatatac aacacgaata
    15901 caattgctac cacaacaatt gcaacgatat acatgtaaag ttttcgttct agtttggaat
    15961 agtcgttttt tttatttttc aattttataa ccaacccccc ataccgtttt tatatatttc
    16021 ggattatcaa tggtgtcgtt cattttttcg cgcaaatgcc ggatatgcac ggtgatggtg
    16081 ttgttgctct tgctgaaata ttcgtcgccc catatctcat gaaatagcag ctcggagcta
    16141 accacattcc ccttgttttc acagaggatt cgcagtattg aaaactcggt gggagtaagg
    16201 gataactgct tctcgttcag ataacactca tgggtgttaa cattaatgac aaggccggag
    16261 tggacgataa cattttcgtt ctgctccttt actccactga attttttgta tcggcgcaac
    16321 tgggccttta cccgagcaat taactccagt gggcgaaagg gcttcgttat ataatcatcc
    16381 gcgccgattg ttaaccctgt aattttatct acctctgtat ctttcccggt cagcatgata
    16441 atcggatagg tgtgcttgtc ccttattttt tgacagatag taaggccgct tgtgccggga
    16501 agcatgatgt ccaatatggc aaggtcaatc tcagacttgt ctatacattc caatgcttct
    16561 ttggcggtat agtatttgaa aaccgtataa ttctcgtttt ttaagtataa ttcaaccaaa
    16621 tcggcaattt catgttcatc atccacaata agtattttat cgctcatagt tatcaccctt
    16681 tcacataagt ttgcccttaa taatttatca gattataggg ccgaatttat aagcatttac
    16741 ataataaatg actaagaatt tcttaagatg atgattcttt ttttatcaaa gggcttttcg
    16801 gcatcgctag gaggctgtta atattttata gtttcctttt cttctttaaa aatattgccc
    16861 attagcggaa tacagaatgg ctaattattc acttctgata atttcctgta taatgaagcc
    16921 ctagatacat tagtaatttc acaaatttga tttacagtca tatttccttc tttatatagc
    16981 tttaccgcat aattcattcc tgcgtgattt ttatgatact tctttaatcg acctttaaac
    17041 tttccttctt tcttagccaa ttcaatccct tcacgttgtc tcatccgaat aagatctcgc
    17101 tctaattggt taacaccagc cattacagta attaagaatt ggctgtatgg attatcttct
    17161 gataaatcaa gccatgtatc ttttagtgat tttaaacttg cctttttatc tcgtatgtta
    17221 tcgattaatt caaatagatc ttgtgtacta cgagtgattc gagttaagtc tgtaacataa
    17281 atgatgtcat cttcctgtag
//
