LOCUS       NZ_CP072570            27191 bp    DNA     circular CON 29-APR-2024
DEFINITION  Enterococcus faecium strain VB3895 plasmid pVB3895_p3, complete
            sequence.
ACCESSION   NZ_CP072570
VERSION     NZ_CP072570.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN18533866
            Assembly: GCF_017815675.1
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27191)
  AUTHORS   Balaji,V., Yamuna,B. and Monisha,P.
  TITLE     Complete genome of Vancomycin Resistant Enterococcus faecium_VB3895
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 27191)
  AUTHORS   Balaji,V., Yamuna,B. and Monisha,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-MAR-2021) Clinical Microbiology, Christian Medical
            College, Ida Scudder Road, Vellore, Tamil Nadu 632004, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2021
            Assembly Method                   :: UNICYCLER v. v0.4.8
            Assembly Name                     :: VB3895
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 44.3x
            Sequencing Technology :: Illumina HiSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_017815675.1-RS_2024_04_29
            Annotation Date                   :: 04/29/2024 04:33:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,062
            CDSs (total)                      :: 2,972
            Genes (coding)                    :: 2,868
            CDSs (with protein)               :: 2,868
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 35 of 104
            Pseudo Genes (incomplete)         :: 70 of 104
            Pseudo Genes (internal stop)      :: 25 of 104
            Pseudo Genes (multiple problems)  :: 20 of 104
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP072570.1.
            Bacteria and source DNA available from Christian medical college.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..27191
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /strain="VB3895"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /plasmid="pVB3895_p3"
                     /geo_loc_name="India"
                     /lat_lon="12.9165 N 79.1325 E"
                     /collection_date="2019"
                     /collected_by="Christian medical college"
     gene            13..>195
                     /locus_tag="J7291_RS14760"
                     /old_locus_tag="J7291_14765"
                     /pseudo=""
     CDS             13..>195
                     /locus_tag="J7291_RS14760"
                     /old_locus_tag="J7291_14765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /name="IS6 family transposase"
     gene            171..527
                     /locus_tag="J7291_RS14765"
                     /old_locus_tag="J7291_14770"
     CDS             171..527
                     /locus_tag="J7291_RS14765"
                     /old_locus_tag="J7291_14770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_029756604.1"
                     /translation="MWQTTLSNFDFKPLGLAIKEARLSKGLTREQVGSMIQIAPRYLTN
                     IENKGQQPSFHVVYDLVTLLNISLDGFILGEENSHKSSKRLQVEAQLDCLDEDELVTIG
                     KVIQAIYGEKCKFN"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(1041..1208)
                     /locus_tag="J7291_RS14770"
                     /old_locus_tag="J7291_14775"
     CDS             complement(1041..1208)
                     /locus_tag="J7291_RS14770"
                     /old_locus_tag="J7291_14775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="WP_005228365.1"
                     /translation="MCPICGNKTRLKMREDTELKNFPLFCPKCRQEILIEITKFRITVI
                     TEPDAKTQSR"
                     /name="cysteine-rich KTR domain-containing protein"
     ARG             complement(1297..3236)
                     /name="tet(S)"
                     /gene="tet(S)"
                     /gene_name="tetracycline-resistant ribosomal protection
                     protein"
                     /tool="rgi"
                     /drug_class="tetracycline antibiotic"
                     /identity="99.84"
                     /coverage="100.78"
     ARG             complement(1300..3221)
                     /name="tet(S)"
                     /gene="tet(S)"
                     /gene_name="tetracycline resistance ribosomal protection
                     protein Tet(S)"
                     /tool="amrfinderplus"
                     /drug_class="TETRACYCLINE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            3915..4595
                     /locus_tag="J7291_RS14785"
                     /old_locus_tag="J7291_14790"
     CDS             3915..4595
                     /locus_tag="J7291_RS14785"
                     /old_locus_tag="J7291_14790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            4793..5398
                     /locus_tag="J7291_RS14790"
                     /old_locus_tag="J7291_14795"
     CDS             4793..5398
                     /locus_tag="J7291_RS14790"
                     /old_locus_tag="J7291_14795"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="WP_000599739.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTFK
                     GLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEIIKK
                     YVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDLEIR
                     YLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
                     /name="protein adenylyltransferase Fic"
     gene            5414..5986
                     /locus_tag="J7291_RS14795"
                     /old_locus_tag="J7291_14800"
     CDS             5414..5986
                     /locus_tag="J7291_RS14795"
                     /old_locus_tag="J7291_14800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000170424.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRDR
                     PKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTSMG
                     RMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELLTSG
                     KSYKEVEAITGFSRSTLFRIKKKIEES"
                     /name="recombinase family protein"
     gene            complement(6459..7031)
                     /locus_tag="J7291_RS14800"
                     /old_locus_tag="J7291_14805"
     CDS             complement(6459..7031)
                     /locus_tag="J7291_RS14800"
                     /old_locus_tag="J7291_14805"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="WP_073120187.1"
                     /translation="MCQKNCCHSIISKENLLNQDFSTETICEKWAADITYIPTKKNGWC
                     YLSSIMDLHTKRIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMILHTDLGSQYTAREV
                     EQWLKTNKIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDFEEANRALFSYIEGF
                     YNRNRIHSSIHYLTPQEFEELAKEKMA"
                     /name="IS3 family transposase"
     gene            complement(7132..8294)
                     /locus_tag="J7291_RS14805"
                     /old_locus_tag="J7291_14810"
     CDS             complement(join(7132..8018,8018..8294))
                     /locus_tag="J7291_RS14805"
                     /old_locus_tag="J7291_14810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage=""
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="WP_086953888.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELTASAFDKWV
                     KQFKTSGSFKEKDNLTPEQKELLELRKRNQQLEMENDILKQAALIFGPKRQVIDANKHL
                     YPISAMCRILGLSRQSYYYQSKPKKDESELEEVVAEEFIRSRKAYGSRKIKKALSKRGI
                     QISRRKISRIMKNRGLKSSYTVAYFKVHHSTCNEAKTTNVLNRKFLRDNPLEAIVTDLT
                     YVRVGKKWNYVCFILDLFNREILGYSCGEHKDAVLVKKAFSRIKQPLTEVEIFHTDRGK
                     EFDNQAIDELLTTFDINRSLSHKGCPFDNAVAESTYKSLKVEFVYQYTFETLQQLDLEL
                     FDYVNWWNHLRLHGTLGYETPVGYRNQRLAQRILDNELGCANASEAV"
                     /name="IS3 family transposase"
     gene            complement(8700..8954)
                     /locus_tag="J7291_RS14815"
                     /old_locus_tag="J7291_14820"
     CDS             complement(8700..8954)
                     /locus_tag="J7291_RS14815"
                     /old_locus_tag="J7291_14820"
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="WP_000199136.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYLP
                     DQSTGLTGKEVAELRKENARLNEELEILKKAAAIFSRKT"
                     /name="transposase"
     gene            complement(9147..9422)
                     /gene="prgO"
                     /locus_tag="J7291_RS14820"
                     /old_locus_tag="J7291_14825"
     CDS             complement(9147..9422)
                     /gene="prgO"
                     /locus_tag="J7291_RS14820"
                     /old_locus_tag="J7291_14825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA segregation protein PrgO"
                     /protein_id="WP_001196543.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVDP
                     PVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
                     /name="prgO"
     gene            complement(9394..10347)
                     /locus_tag="J7291_RS14825"
                     /old_locus_tag="J7291_14830"
     CDS             complement(9394..10347)
                     /locus_tag="J7291_RS14825"
                     /old_locus_tag="J7291_14830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_000429439.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLFE
                     KDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGSPG
                     SEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAADYII
                     AMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQKTID
                     KYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYYEQHGD
                     IEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
                     /name="ParA family protein"
     gene            10959..12452
                     /locus_tag="J7291_RS14830"
                     /old_locus_tag="J7291_14835"
     CDS             10959..12452
                     /locus_tag="J7291_RS14830"
                     /old_locus_tag="J7291_14835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="WP_000947691.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSKQ
                     LMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINTFV
                     VDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVIDVA
                     KKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSMKLES
                     DQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTLSLAYY
                     SSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELCQQWVSP
                     TLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLNLSKKELA
                     SQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLSKEKRLDYS
                     TRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
                     /name="primase C-terminal domain-containing protein"
     gene            12587..12883
                     /locus_tag="J7291_RS14835"
                     /old_locus_tag="J7291_14840"
     CDS             12587..12883
                     /locus_tag="J7291_RS14835"
                     /old_locus_tag="J7291_14840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication control protein PrgN"
                     /protein_id="WP_000053907.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTRE
                     KTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
                     /name="replication control protein PrgN"
     gene            complement(12907..13866)
                     /locus_tag="J7291_RS14840"
                     /old_locus_tag="J7291_14845"
     CDS             complement(12907..13866)
                     /locus_tag="J7291_RS14840"
                     /old_locus_tag="J7291_14845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="WP_000222573.1"
                     /translation="MTYTHLTTDELVMIESYFKINQSVAKTAHCLNRSRQTIHKVYLFF
                     KQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIRCS
                     ARTIYRMFKKGLFNPSDLPMKGKRKPNGHQERRGKQAFRRSIHEREKDYSQFSNEFGHL
                     EGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIENKLNHWFESVPKNLFKSITF
                     DCGKEFSNWKQISNANDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNSVDESF
                     IQSVASKRNNIPRKSLNYRTPLEVFLSYVSIDDLSNLI"
                     /name="IS30 family transposase"
     gene            14049..>14654
                     /locus_tag="J7291_RS14845"
                     /old_locus_tag="J7291_14850"
                     /pseudo=""
     CDS             14049..>14654
                     /locus_tag="J7291_RS14845"
                     /old_locus_tag="J7291_14850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358225.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            14729..15409
                     /locus_tag="J7291_RS14850"
                     /old_locus_tag="J7291_14855"
     CDS             14729..15409
                     /locus_tag="J7291_RS14850"
                     /old_locus_tag="J7291_14855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            15546..>16499
                     /locus_tag="J7291_RS14855"
                     /old_locus_tag="J7291_14860"
                     /pseudo=""
     CDS             15546..>16499
                     /locus_tag="J7291_RS14855"
                     /old_locus_tag="J7291_14860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /name="IS256-like element IS256 family transposase"
     gene            complement(16549..17229)
                     /locus_tag="J7291_RS14860"
                     /old_locus_tag="J7291_14865"
     CDS             complement(16549..17229)
                     /locus_tag="J7291_RS14860"
                     /old_locus_tag="J7291_14865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            17360..17812
                     /locus_tag="J7291_RS14865"
                     /old_locus_tag="J7291_14870"
     CDS             17360..17812
                     /locus_tag="J7291_RS14865"
                     /old_locus_tag="J7291_14870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000751236.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNKK
                     MSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSELVS
                     YKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
                     /name="hypothetical protein"
     gene            17826..18515
                     /locus_tag="J7291_RS14870"
                     /old_locus_tag="J7291_14875"
     CDS             17826..18515
                     /locus_tag="J7291_RS14870"
                     /old_locus_tag="J7291_14875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000718009.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFEE
                     EDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKNDIE
                     TTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFLRWK
                     SYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNPVAGT
                     YYVVQNI"
                     /name="hypothetical protein"
     gene            18640..20991
                     /locus_tag="J7291_RS14875"
                     /old_locus_tag="J7291_14880"
     CDS             18640..20991
                     /locus_tag="J7291_RS14875"
                     /old_locus_tag="J7291_14880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase domain-containing protein"
                     /protein_id="WP_000344083.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQV
                     ELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVYTP
                     YLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLNVNY
                     LEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGNSGNY
                     VRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKGLLSSA
                     GDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTTEELNNI
                     FSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAVDLDMLGE
                     EILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMSTGYSGNLG
                     FPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNYIAKYNQKVI
                     NQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRKIYDEYRNKLT
                     NSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWLGDLMTCWGEVK
                     KLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDSTALSALKTYYCDK
                     GAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFIDKIVNNSLGTDFT
                     YLDFIGDEGKVANGFSEKIIQFQENRSKLN"
                     /name="glycoside hydrolase domain-containing protein"
     gene            21071..21466
                     /locus_tag="J7291_RS14880"
                     /old_locus_tag="J7291_14885"
     CDS             21071..21466
                     /locus_tag="J7291_RS14880"
                     /old_locus_tag="J7291_14885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002304891.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIVD
                     YFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKKKE
                     YNYIVKAKVSKRFIFNPKLEIYSVVIE"
                     /name="hypothetical protein"
     gene            21791..22408
                     /locus_tag="J7291_RS14885"
                     /old_locus_tag="J7291_14890"
     CDS             21791..22408
                     /locus_tag="J7291_RS14885"
                     /old_locus_tag="J7291_14890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001224538.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFKR
                     PEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTASY
                     KQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPPEFP
                     AIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
                     /name="recombinase family protein"
     gene            22449..22748
                     /locus_tag="J7291_RS14890"
                     /old_locus_tag="J7291_14895"
     CDS             22449..22748
                     /locus_tag="J7291_RS14890"
                     /old_locus_tag="J7291_14895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="WP_000366408.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFLV
                     CGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
                     /name="BRCT domain-containing protein"
     gene            22782..22949
                     /locus_tag="J7291_RS14895"
                     /old_locus_tag="J7291_14900"
     CDS             22782..22949
                     /locus_tag="J7291_RS14895"
                     /old_locus_tag="J7291_14900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000824191.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCPK
                     CHRRYGVHGT"
                     /name="hypothetical protein"
     gene            complement(22994..23599)
                     /locus_tag="J7291_RS14900"
                     /old_locus_tag="J7291_14905"
     CDS             complement(22994..23599)
                     /locus_tag="J7291_RS14900"
                     /old_locus_tag="J7291_14905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_002321606.1"
                     /translation="MGKIGYIRVSSQDQNLDRQLAMMEGLNIDKLFQEKASGKDTERPE
                     FQKLLNYIREGDCVIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGNEL
                     LDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQKRL
                     VFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
                     /name="recombinase family protein"
     gene            23724..26711
                     /locus_tag="J7291_RS14905"
                     /old_locus_tag="J7291_14910"
     CDS             23724..26711
                     /locus_tag="J7291_RS14905"
                     /old_locus_tag="J7291_14910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="WP_000343406.1"
                     /translation="MDEIKSNKKAFGIYLGEPSTEQLNQFFYLHEKDLELMETIRRPAT
                     RLGFALQLVSLRFLGTFILDLTNIPQNVLSYVATQLNIDPGEIIYYSRRQTRYQHTKLI
                     KSHYGYQDFNQPEIETYLANWLLNRALYTTESSDMLFDMLLKKCLDEKIVLPGITTFSR
                     FVASAIEKAEEHLYRQLSLVPTEDERKRLLNHLELIGTPVYGAIIKMDILRTPLADDSH
                     KEIARGFDRLKQFQAFSTEKWKMESIPEGKIKVLANYAFKAKAQLIQRMSEQKKLALLV
                     AFIFIYKRKAMDEQILALSNFFETVFRRAKNKESKERLRTIKDLDRAASTLSDIVDLVM
                     SSHSDTNELSLRDRILEKYSEENVTEAVSQVRLLVKNDREPIAISELLNTYRKFRKFIP
                     DILTTLTFDSNDYGNNCKELWTFINNRFPKPITYKMFGAIKHTLPKKWIYYIHEYPEQT
                     NKCVLIAAVELLIQSLKRHDIYIPQSVLYNNPMDCLIDEKTWVQQKYVLLEQLDLPSSA
                     NEMSLWLKNDLELSYKEALNRWPTSKMARIENADRLVVSRLKKTYEKKEDKSFRRRIQQ
                     LLPKIDLSDLLLEVNQQLNLTQSFNHLSDKDTKMKDLDISLLAVLLSESCNIGFSPVSK
                     EGFDSLKYDRLVYVNHHYIRVDTLSGANQKIIHAHRKLATSKIWGDGHMASADGIRYIT
                     PQRSLYSRSNPKYFGRGRGITFYNFVSDQYIGFHGMVVSGTLRDSLYLLEGFLNQPSEL
                     TPNQIMTDTAGYSDMIFGLFGLLGFQFSPRIANDKGTKLWRIDANAHYGELDTLSQNSI
                     NMELIYTHWEDILRVAGSLKSGKVNATELTKSLQRNGQPTPLGKAITEYGKVYKTKHQL
                     RYISDEIYARQILEQLNKGEARHALCRNIFYGRKGKLYQTYYDGMEEQLNALGLVTNAI
                     IYWNSLYLEKVFEQMKAEGFDCSEEMIRRQSPLISDHINFVGKYTFRYEAELSNGKLRP
                     LNVEEF"
                     /name="Tn3 family transposase"
     gene            26860..>27069
                     /locus_tag="J7291_RS14910"
                     /old_locus_tag="J7291_14915"
                     /pseudo=""
     CDS             26860..>27069
                     /locus_tag="J7291_RS14910"
                     /old_locus_tag="J7291_14915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346508.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /name="DNA topoisomerase"
     Typing          10960..12452
                     /name="rep_cluster_185"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 ggaggaatga cgatgaatca ttttaaagga aagcaatttc agcaggatgt gattattgta
       61 gccgtgggct actatcttcg ttataacctt agctatcgtg aagttcaaga aatcttatat
      121 gatcgtggca ttaacgtttc tcatacgacg atttatcgtt gggtgcaaga atatggcaaa
      181 ctactctatc aaattttgat ttcaaaccat tgggtcttgc gattaaagaa gcccgtctta
      241 gtaaaggatt gactcgtgag caggtaggat caatgatcca gattgcgcca cgctatttga
      301 cgaacattga aaataaagga caacagccaa gttttcatgt tgtatatgat ttagtgactt
      361 tgctaaatat ttctttggat ggatttattt taggggaaga aaacagtcat aaaagctcca
      421 aacgtcttca agtagaagca cagttggatt gtctggatga agatgaatta gtgacgattg
      481 ggaaagtgat tcaagcaatt tacggagaaa aatgtaaatt taactagttc aataatacac
      541 aatggattaa ttaatactat caggaaagat tgattacaaa gatgtaatga attttttctg
      601 atttttgtta atcataaata gaaaatgaat ttatctttgt tacacttagg aactagagcg
      661 aatgataaat agttctttgg ttactcttat cgctgcaaag tacagttcat tttttgttgt
      721 tgggaaaatt ttctggattt attgcatatc acttcatccg actaaaaatt tttgattccc
      781 atagcgaagt tcgtttttgt tccttaggaa aaacttgact gatatactag ttttgaaatg
      841 acgagtaact ctgtacttca tcaataatca agtattgaat tttaattgta tactttttat
      901 gcttgaggga tgtctactgt aatacagcta ctgcaaaaaa aatcagtaca cttattttct
      961 tataaaggat atcaagaact aagctcaatg gtatgcatag aaaagaaaaa gccgataaaa
     1021 tgagattttg atatctcgaa ttatcggctc tgcgtctttg cgtctggctc tgtaattaca
     1081 gttattctaa acttcgttat ttcaattaaa atttcttgtc tgcatttagg acaaaataga
     1141 gggaaatttt ttaattcagt atcttccctc atttttaaac gggtcttatt gccacatata
     1201 gggcacagta tccacctagt atttacaata tctatatcct cctgttctaa ttaacaactc
     1261 aatattcatt ttaaaaattt ctctttagtt cactatcaat gtaagttgat tttattaaac
     1321 atatgcctta ctttgtctat tctattattt ggacgacgtg gttggaaagc agacttaatg
     1381 ttagtaacct gataaccttt taactctgtt aaacagacac tgcgtccatt tgtaaagaaa
     1441 gttaaactgt ttcgatactc ttgaatacaa cgggctggaa tttcaccaat gagaatgacc
     1501 tcgttacctt ttaacttagt atttaaaata tttgcacaat atttggaagc atcattatat
     1561 gctctcgaaa gatattcttg tggtacataa atttcgaagc taagatatgg ctctaataac
     1621 tctgtaccac tctttctaaa agcctgctct agtacaatag gcgcaagcat tcggaaatct
     1681 gctggcgtac tgacagggct gtaatataga ccatacttaa aacagatctt acagtctgtt
     1741 aatttccaac cgtacaatcc ttgttcacac ccatagcgta taccttccat aactgcattt
     1801 tgaaatgatt gatttaaata acctagagaa accaggctct catactgaat gccactaccc
     1861 aaaggaagtg gtgttacaga taaaccaata gaagcccaga aaggatttgg aggtacttcg
     1921 atatcaatgg taaattcaga tttttttaat ggtctttcca tataaatgac agttggtttt
     1981 cttgtttcta tctcaatatg atatttttct tgaatcagag tacaagttac ctccatttgg
     2041 acctcaccta aaaaagatag cacaatttcg tgagttactg tatctacata atattgtaga
     2101 aggggatcac tatcggatat ttcaaaaagt gcatctagta acttttctct ttgtactgat
     2161 ttacatggtt caattgttgt ttgtaacata ggaagaggat tctcaagaat ttctctatgt
     2221 ggtaatcttt ttttatctcc aagtacgtta tttagtttta aaagctcatt ttttaaaata
     2281 ataatctcac caggctctgc cttatctatc tggcgtaatt ctccatttat tgaagtatac
     2341 atttctgtaa cttttatttt ttccttttct gatatattga ctgagtctcg caaatgtagc
     2401 gttccactat aaagacgtac atagacaagc cgttgaccat catctgaata ttctacttta
     2461 aaaacatttc cacaaagttt atctgaattg agttgtgtgg gtgaaaataa tttgctagta
     2521 attacctcta taagttgttt aattccaata ttattctttg cacttccgtg ataaacagga
     2581 tataaggagc aactttgaat tctttcgttt tcctcctttt caagttctgc aatattcaat
     2641 gttttcccaa tggtatattt ttctaataaa taatcatttc ccacaattac tgtctcccat
     2701 tgttctggtt cagtataatc tattacataa ggtttcaaat ttagattcac agtctgctta
     2761 attatgatgt cgtcagaaag tttgtcctta atatcttgat aaacatctgg caaatttatt
     2821 ccattttgat caattttgtt aataaaaaat attataggta tgttcatctt tctaagtgca
     2881 tggaatagta tacgagtttg tgactgtact ccatcttttg cagagattag caaaatagct
     2941 ccatccaaaa cagataatga acggtataca tctgccaaaa aatccatgtg tccaggagta
     3001 tctacaatat ttactttaac attttcccgt tgaaaagatg ttattgcggt ctgaatagta
     3061 atacctctct ggcgttccaa aaacatagta tccgttttcg ttgtaccgct atctacactt
     3121 cctaactctt taattgctcc gctactgtat agtaagcttt ctgtcaaagt agtttttcct
     3181 gcatcaacat gtgctaagat accgatatta ataattttca attttatttc ctccattcaa
     3241 aagctcaaaa agcagaaaaa atcccagtga taaatactct tatcactggg attttaatac
     3301 aaaaatagct gtatactaca cactgatagc cacagatgct ttatgataaa atgataaaag
     3361 tattcttaaa ctgggcacaa aaaaccagtc cttattttaa ataaggatgc ttaattaatt
     3421 attcccgcta tctaattgac agtttattta agaatacctt gccgcatttt tattatctcc
     3481 ttttgaatgt tatcttaatt ctatcatatg atagaatgct tgtaaagcca accatatttt
     3541 ttgaacgaaa gggaaattaa tgagaaatta atggaagtta gtgtagtagt tgaagataac
     3601 tcttcagaat ggctatcaaa attcagcgat ttaataacga tttacaagtt cataagggat
     3661 tctttattca tccagctatt atattacttt tcaggtcaat aggacaactg tccacaacct
     3721 ttctacaaat atattacgta taatttttga aatatatact gcttaacaaa atattttgca
     3781 gtggttccaa tagttttgaa ttgttaatat taagtttgac ttggaaaata tcattaaaag
     3841 ggttctgttg caaagtttta aatctactat caaataaggt agaataatag aaaaagatag
     3901 caggaggaat gacgatgaat cattttaaag gaaagcaatt tcagcaggat gtgattattg
     3961 tagccgtggg ctactatctt cgttataacc ttagctatcg tgaagttcaa gaaatcttat
     4021 atgatcgtgg cattaacgtt tctcatacga cgatttatcg ttgggtgcaa gaatatggca
     4081 aactactcta tcaaatttgg aaaaagaaaa ataaaaaatc cttttattca tggaaaatgg
     4141 atgaaacgta catcaaaatt aaaggaaaat ggcattattt gtatcgagcc atcgatgcag
     4201 atggtttaac cttggatatt tggttacgta aaaaacggga cacacaagca gcctatgctt
     4261 ttcttaagcg gttagtgaag cagtttgatg aaccgaaggt tgtagtcaca gataaagccc
     4321 cctctattac aagtgccttt aagaaactaa aagaatacgg cttttatcaa gggacagaac
     4381 atcgtaccat taaatacctg aataatttga ttgaacaaga ccatcgtcca gtaaagagac
     4441 gcaataaatt ctatcgaagt ttacgcactg cctctaccac gattaaaggc atggaagcca
     4501 ttcgaggatt atataagaaa acccgaaaag aaggcactct cttcgggttt tcggtctgta
     4561 ctgaaatcaa ggtattattg ggaatcccag cttaaatcat agataccgta agggatttta
     4621 ttctttattt aaaactttgc aacagaacca actagactgt gcaaaataga gacacttgaa
     4681 aaatctatcg ggggtcagaa acttaatagt ttttgacaca taaacaaaat cgcgatataa
     4741 tggggttgag agtgtttcat aaacttatgt cataaagtta aggagatttc gcatgatttt
     4801 agagaataaa ttgggattaa ccaatcaagt tgagttggct aaggttgaag aaaaactcag
     4861 taaacaaaaa gcgaaagaat tgtacgattg tggaaaaata aatgaaatcg aagttggtac
     4921 atttaaaggt ttatctgaaa ttcatgaatt tctattttcg gatatttacg attttgccgg
     4981 aaaaatccga tcggtcaata ttgcaaaagg aaattttcga tttgcaccag ttatgtattt
     5041 agaacattcg ttacagcata ttgatcagat gccacaaact tcttttgaag agattatcaa
     5101 gaaatatgtg gagatgaata tcgctcaccc atttcgagaa ggaaatggcc gaagtactag
     5161 aatttggctg gatctcattt taaaggaaga attgcaaaaa gttgtagatt ggaacttaat
     5221 cgataaagca gactatcttt ctgcaatgga gcgaagtccc ataaacgatt tggaaatacg
     5281 ctatctaatt tccaatgctc tgactgataa aattgacgat cgcgagttat atatgaaagg
     5341 aatcgatgtc agctatttct atgaagggta ttctgagtat acgatagatg atttgtaaaa
     5401 gtaggtggac caaatgacga aatatggata tgcacgtgtc tcaaccgctt ctcaaagtac
     5461 aaaagaacaa attcaacagt tgcttgagaa cggcgtagag aagaagaata ttttttcaga
     5521 aaaatttacg ggtacaaaac gggatcggcc aaaattcaat cagctgttgg ctggtctgaa
     5581 gcctggagat gaaatagttg ttacgaagct tgatcgattt gctcgtaaca cgagagaagc
     5641 attagagatc attgaacctt tactcgatga taacgtaacg atcaaggttt tgaatctagg
     5701 aacgattgaa aatacgtcca tggggcgaat ggtgacacgg acgttgttga gtgtagcaga
     5761 aatggaacgt gatatgattg tggaacgtac ccaagaagga aaaatgtttg caagaaagaa
     5821 taatcctaat ttcagagaag gacgtccgaa agcaacaatc acaccgaaga agaggcacgc
     5881 atatgaactg cttacttcag gtaaatcgta taaggaagtt gaagctataa ccggtttcag
     5941 tcgcagtacg ctttttagaa taaagaagaa aattgaagaa agttaaaaaa gaagtctcag
     6001 cgaaccagac aggtaaatac ttaatgcgtt ctagatatga gtctattagc atgttgtgaa
     6061 atataatatt tttttattta cttgatttct gctcaaaaaa tgtgtatggt aactgtaaaa
     6121 ggtaaagtaa ttaaaggtat gctagccacg cttactatat taggatacca tcatatattt
     6181 ataatgaacg atttgttcgt ctaccaaaca acacatatcg ttcagcgtaa gtcacgttta
     6241 ggaacgtggc ttttttagtg ttattatcga taaataatct attgactcta ttgattttat
     6301 ctccatatcc ctacggtgtt gattgtcttt agatctttca tttaagaacc aaataactat
     6361 cataaaaatc agcactgctg ctaatataat aaacagcatt cctattgtga tattactgga
     6421 tttgagtcaa tatcttggac acattttagt agagacggtt aagccatttt ttcttttgct
     6481 aattcttcaa attcctgtgg ggttagatag tgaatcgagc tatggattcg atttcggtta
     6541 taaaatcctt caatgtagct aaatagcgct cgatttgctt cttcaaaatc tgagtagcta
     6601 gtcgtgtaga cttcttcttt tttcaatgag gcatggaaag attcgattcc agcattatca
     6661 taaggtgttc cttttctact ataagaatgc cttattttgt tggttttaag ccattgttcc
     6721 acttctcttg ctgtgtattg gctgcccaag tcagtgtgta gaatcattcc ttctggaatg
     6781 tgataatgta tttttgcttt attcaatgtt tgaatgacac aatccacagt cattcgtttt
     6841 gaaaatgtat aactaataat tcttttcgtg tgtaaatcca tgattgaaga taagtaacac
     6901 caaccatttt tcttagtagg aatgtacgta atgtcagctg cccatttctc acagatcgtt
     6961 tcagtagaaa agtcctgatt taagagattc tcttttgaaa tgatggaatg gcaacagttt
     7021 ttttgacaaa ttttataagg tgcagaactt ctttccgtat gctattccga ttgtccttga
     7081 caatgagcct cctcggatgt gacgatcttc ggcaggagct aacagttaaa gttagactgc
     7141 ctcgctagcg ttagcacatc cgagctcatt atcaaggatt cgctgcgcca atctctggtt
     7201 acggtaacca accggtgtct cgtagccaag tgtaccgtgc aaccgaaggt ggttccacca
     7261 attgacatag tcaaataact ccaaatccaa ttgttgtaag gtttcaaatg tgtattgata
     7321 gacaaattct actttcaacg acttataagt tgattcagct acggcattat caaaaggaca
     7381 gcctttatga ctcaatgatc gattgatgtc aaaagttgtt aataattcat caatagcttg
     7441 gttatcaaac tcttttccac gatcagtatg aaaaatctca acctctgtca gaggttgttt
     7501 gatacggcta aatgcttttt ttactagaac ggcatcttta tgttctccac aagaatagcc
     7561 gagaatttct cgattgaaca gatccaaaat gaaacagaca taattccatt ttttcccgac
     7621 tcgtacataa gtcaagtctg ttacgatcgc ttctaatggg ttgtctctta agaatttacg
     7681 attcaatacg tttgtcgttt tggcttcatt gcaagtagaa tgatgtactt taaaataagc
     7741 aacagtatag ctcgatttta atcctctatt tttcatgatt ctactaattt ttcgtcggct
     7801 gatctgaatg cctcgttttg ataaggcttt ttttattttt cttgagccgt aggcctttcg
     7861 gctgcggata aattcttcag cgactacttc ttcaagttct gattcgtctt tctttggttt
     7921 tgattgataa taataggact gacgtgatag acctaatatt ctgcacatcg ctgatatagg
     7981 gtaaagatgc ttattcgcat cgattacttg tctcttcgtc cgaatatcag cgctgcttgc
     8041 tttaaaatat cattttccat ttctaattgc tggtttcttt tacgtagttc taacaattct
     8101 ttttgttcag gcgtaagatt atctttttct ttgaatgaac cactcgtttt aaattgcttt
     8161 acccatttgt caaatgctga agccgttagt tcatattctc gaatgatttc tacacgtggc
     8221 tttccagcta agtaaagatt gacgatttgt tgcttgaatt cttgtgaaaa agttcttcgt
     8281 gttctcttag acataaaaat tcctcctggt atgttttctt ctagtctaca caccttaatt
     8341 tttctgtcta gttaattgta gcctatccat gatcggttta ttagaccttt gaggtctata
     8401 ttttttaact acaatcgacc ttaaatttaa ttgtttcatt agcttttgga catgtttaag
     8461 agatactgaa atcccttctt ttaataaaac ttgatggatc tttgtggcac catagcgttg
     8521 tttattcgta aaaaaaattg ttgaaatctt ctttttcaac ttattatttc tgatttctgt
     8581 agctgtcaac ggtttattct tataaaaata atagacactt ctagggattt ctaataaccg
     8641 acacaacaaa gaaacagtgt aatccttaca ccatttttca ataaattgaa caagcgaatt
     8701 taggttttcc gagagaatat ggctgcggct ttttttaaga tttcaagttc ctcatttaaa
     8761 cgagcatttt cttttctcag ttcagctact tcttttccag tcagtcctgt ggactgatca
     8821 ggtaaatata aattcttcca tttgtaaatc gttgcttcag ataagccata ttctttcgct
     8881 aaccctcgaa cagaacgtcc agtttgattc agttcaacaa tcatttgttt aaaattttct
     8941 tcatatcggg tcataaaaat tcatcctctc gtagataagt ttaatttatt cttgtctcta
     9001 cgaaaagctg tctaagattt gatactaaca ccaaatgttg tataccccca aacaatacac
     9061 atattttgaa ggattaggat taataaagct aaaaatatag taagtatact aaatatattt
     9121 actatatcta gtatacttac tatattttaa tcttttgatc gtctattata tataatccgt
     9181 tcctcgtcgt ttaaagtatc aacataggcg tccattgcaa gtttgactat ttcatacata
     9241 ggaatatctt ttgcataact aagatcccga atggttttta gtacgggagg atctacttga
     9301 actggttttc tttctttcgc agtgtacttt cgttccccta actcgacatt aatatcatct
     9361 ttaattgaaa tatcttcagc accaattttc ttcttatctt tgttcgttgg taataatgcc
     9421 atttagttta atctcctttc caagaggtag gatatgattg gccattgagt cagcatattt
     9481 aggtgtataa tcaaatcctt caatatcacc atgttgttca tagtattcaa ttctttcttc
     9541 taattctgta aagatgtctg caaaaatagc ccaccatctt cgatctacat aatcatttaa
     9601 ttggatacca ttctcaccat acatttctaa ccgatccgag cctttaacaa tgcttttaaa
     9661 aatgtttgat tcaccatact tatcaattgt tttttgatag tttgcgtgtt gagaggaacg
     9721 tcgcactgag aaaagaacag gcaaaattcc aatgatttga agatgagact cttcaaaatt
     9781 cgtgacaatc ggaactaaaa ctttattaat aaaatcttct gttccttcca ttgcgtaccg
     9841 ttttaattct tgcattgcaa taatataatc tgcagcagtt aagaatgcac gaaccacatt
     9901 atctgttgat ggtgggcagt cgataaagat ataatcgaaa ttttttctca attcttctaa
     9961 aggtttaatg aaggccaatg atctcttacg acgatcagga tatttttcgg acaagtattc
    10021 attaagttct tcagatccag gagagccagc cataatatat aaatgtggac ttacttgagt
    10081 aatacctgaa acccagtccc cttttttgat tgctgcagac atggatcgat caaagctagt
    10141 aatttgatac gttgatccaa tgttggaagt agtatttctt tgttggtcat aatcaattag
    10201 caacacgtct ttttcaaaaa gttgactaga aacaatcgct aataaatcat tgtctgtagt
    10261 cttaccaatg ccgccttttc tacctgtaag cattacaact tttcctagtt tatctgatgt
    10321 tttaaatgca gtccgtaagt tttccatagt tccctccaat ttcctatact aaatatattt
    10381 agtatacttc atatacttaa tatattcgat atatctaata tactccaaat tgataagaat
    10441 tcagacttta taaggaatat agtggatata ctaaatatat ttgctatatt cagtatatca
    10501 gatatattca aaatgtcaaa atatatttgt gcgttttgcg ttgacaattt agagtgaaaa
    10561 gaggtaaact taattctata gaaaccacag ataattcact atttacaaag tagcaaaagc
    10621 agtggtactc tttaaacaga aaaattacat aaaaaaaaga gacggaaata attgatttta
    10681 gcagaatcaa ttatttctga atcacatggt taggacatgt gttcacgctc gtctcaagaa
    10741 tatgtaagta gctaccaact acttatatta aaagttgatc ggataccttt tccgattgcc
    10801 tttattctac caaaaaaagg cgagcaactc aacagaagaa cgtttattta gtgtacttaa
    10861 attaaatatt cttaaacact gaagagagaa cacatactat ggctgagatt aaagctaaac
    10921 tgtgttctct ttttgtttga gaaaggacgt tacaatcgat gttgagcgaa atttattcag
    10981 ctattcttaa aaacggctta cgtacataca aatatcgaaa cagcaccatg aaacctgcag
    11041 gtcatattga ttccagtagg agtggtgcta tctttgcgta ccgtagcaag caattaatga
    11101 atgttgggcg tggtatggtc attacttcgg aagaagctat tttagagaac gaaaagaaac
    11161 taacgcattg gacacctaat acctatcgct ttggtactta tgcggatgat tatcgaacag
    11221 tggttaaagg tcattctgag aaaaacttaa gtcaaatcaa cacatttgta gttgatatcg
    11281 attcaaaaga gaaccatcaa ggcgaaatta ttttagcctg tttagatcaa gtgggctaca
    11341 tgccaacgct aattttagaa tcagatcatg gttatcaagt ttattttgta ctaaagacac
    11401 caggctatgt cacaaagaaa agcaatttca aggtgatcga tgtagcaaaa aaaatttcaa
    11461 aaacaattcg tctacagttg gctgaaaaat tgtccggagt ggatctagga tgtaaccact
    11521 tcggaattgc tcgattccca caagaaaata atattgtttt taaagaaatg aactatcagt
    11581 attcttttgc tgactggatt caatggtcga tgaagcttga atcagatcaa aaaacaaaag
    11641 aagatcgaga acgaaaacta attgtctttc ctgagaaaaa agaaattcgt caagtagatg
    11701 aaccgtggtt cgatatgtta cttcataaag caaacatcgt cggcggagaa ggacgtcttg
    11761 gtcgaaataa tgtgattttc acgctttctt tagcttatta ctcttcaggt tatgcattgg
    11821 atacttgcga atacaatatg ttcacattca acgaacggtt acaggaaccg ctatctgaag
    11881 cagaattagt aaagattgta cgtagtgctt attctggtaa ttatcaagca gcaagcagag
    11941 aattcattat tgaattgtgc cagcaatggg tttcaccaac cttaaaaaat aatgatctgt
    12001 tcattcaacg acgtggctgg tggaaattta aaaagccacg agatcaaaga aaatatagtc
    12061 ataaaaatga atggaaagaa gatctattgg cttatctaag cgaaaaaagt cttgctagtg
    12121 agccttattt gaacctgtca aaaaaagaat tggcttcaca actaacgatg cccaagcgaa
    12181 cacttgataa gatcttaaat gagttacgag aggagaataa agtcttctac aaggtaacac
    12241 gaggaagaaa tggcggaatg atcattgctt cagtcaaaac gttgttcgcg agggttattc
    12301 aactaagtaa agaaaagaga ctagattatt caacaaggat cacagaggta tttggactca
    12361 acgagagctt agtagaagag acatttagac aattatcaac ccccttgaac cctcttaaag
    12421 aagtgaatct ttttgaagta gatacaggtt gaaaaataaa aggtgcaaat tgccttatac
    12481 aatatatcta tgatacttct gtaggtgttg ctccctttgc ctagctacgt gtaggtggta
    12541 tacttataac tgcgtatgca gtcttatgta tcatggagga agttgtatgt cgttaaaaaa
    12601 ttatgtctat tcacatcctg ttaatgtgtt tatcattggt cgtttgggat tatctgtgga
    12661 agtgttctgt gagctttatg gttttaagca ggggactttg tcttcttggg ttaccaggga
    12721 aaaaacagtt gcttctttgc cgattgagtt tcttcatggg ttgtccttag cttctgggga
    12781 gactatggat caggtatatg attgtttgtg tgtgttagag caggagtata ttgagtataa
    12841 aatagctaac gagttaagaa aaaggaagaa gtatatccag tagtagtttt tatttactct
    12901 taattgtcaa attaagttag acaaatcatc aatacttacg taactcaaaa atacttccaa
    12961 aggtgttcga taattcagtg attttctagg aatattattt cgtttcgatg cgacagattg
    13021 aataaaagat tcatctactg aattgaaatc catagatttc aataaaccat ctctacgtaa
    13081 caatccgtta gaattctcgt ttaggcctct ttgagacggc gttcctggat cagcgaaata
    13141 aatggcaata tcattggcat tactgatctg tttccaattt gaaaattcct ttccacaatc
    13201 aaaagtgatg gatttgaata gatttttcgg tacagattca aaccaatgat ttaatttgtt
    13261 ttcaatatca atcgcttgtc taccacacgg tttcaatgtg atgataactt ttgataatcg
    13321 ctcaactaag gtaattacag cacttttatg tttcaaacct acgatagtgt caccttcaag
    13381 gtgaccaaac tcatttgaga attggctata atctttttca cgttcatgaa tagagcgacg
    13441 gaaagcttgt tttccacgtc tttcttgatg tccatttggt ttacgcttgc ctttcatcgg
    13501 taagtcagaa ggattaaata gccccttttt gaacatacga taaatggtac gagcagaaca
    13561 acgaatagga aacgctgcac gaccaacaat cacatcgggt gtccatcctt gaacaacctt
    13621 tctttgaata tattctgatt gttcctcagg taaaacaagc gggcgtctac cacagtttga
    13681 tttgtttttc ttatactgtt gatagtactc taaggctgat tttccttgct tgaagaacag
    13741 gtatacttta tggatcgttt gtcttgaacg attcaagcaa tgcgcagttt tcgcaacaga
    13801 ttgatttatt ttgaaataag actctatcat tacaagttca tccgttgtaa gatgggtata
    13861 ggtcatttgt actcactcct tataattctt tggacggaac tattttgagt gtagcacaaa
    13921 tgactttttt agttgtctag cttaatttta caatcggcgt acttaaaaaa ttggttcatt
    13981 gagcaaccta tcgctgctaa agtagcaaag gaaaacgtta aaggaaagaa tttagggaag
    14041 aaatcgaaat gaaatcggac gactggattg aacacacctg gcttcctctg aaaagaaata
    14101 gcaaacgaaa gaaattttgg gtattgcaat tatggccatt aggaaaactt tgtagttacg
    14161 gggcacgact tattcttgat ttaaccgttt actcgattgg agtatttgga acggcttatt
    14221 acttgataaa tgatcccaat aggattgcag catcagacat ttttacagtg ctaatgacgt
    14281 tgatttttgt catgctattg tctattttta ctcaattagt catgcaattt accaggcaaa
    14341 aattaacagc aggaaaactt ttcaaaagcc tattcgattt aattgttgta aatgcaattc
    14401 tagcgacttt aataaaacaa attgaacaat ctggaagaac aacaaaagga gtgaaggatt
    14461 ttttattgac gtttattcac tttgtaaatg gacacatgta tttgtttgaa gtgggtatta
    14521 ttctcttttt tgtcgggtat gtatccacga aacttattaa acgttcaatt gaaaaagaaa
    14581 ttgaaattga cctgattccg acacttcttg gttatgagta caatgttgat tttggaagat
    14641 atgacgaatt gatcggttct gttgcaaagt tttaaatcta ctatcaaata aggtagaata
    14701 atagaaaaag atagcaggag gaatgacgat gaatcatttt aaaggaaagc aatttcagca
    14761 ggatgtgatt attgtagccg tgggctacta tcttcgttat aaccttagct atcgtgaagt
    14821 tcaagaaatc ttatatgatc gtggcattaa cgtttctcat acgacgattt atcgttgggt
    14881 gcaagaatat ggcaaactac tctatcaaat ttggaaaaag aaaaataaaa aatcctttta
    14941 ttcatggaaa atggatgaaa cgtacatcaa aattaaagga aaatggcatt atttgtatcg
    15001 agccatcgat gcagatggtt taaccttgga tatttggtta cgtaaaaaac gggacacaca
    15061 agcagcctat gcttttctta agcggttagt gaagcagttt gatgaaccga aggttgtagt
    15121 cacagataaa gccccctcta ttacaagtgc ctttaagaaa ctaaaagaat acggctttta
    15181 tcaagggaca gaacatcgta ccattaaata cctgaataat ttgattgaac aagaccatcg
    15241 tccagtaaag agacgcaata aattctatcg aagtttacgc actgcctcta ccacgattaa
    15301 aggcatggaa gccattcgag gattatataa gaaaacccga aaagaaggca ctctcttcgg
    15361 gttttcggtc tgtactgaaa tcaaggtatt attgggaatc ccagcttaaa tcatagatac
    15421 cgtaagggat tttattcttt atttaaaact ttgcaacaga acctgtaaaa gtaaaaaggc
    15481 catataacag tccttttacg gtacaatgtt tttaacgaca aaaacatacc caggaggact
    15541 tttacatgac ccaagtacat tttacactga aaagcgaaga gattcaaagc attattgaat
    15601 attctgtaaa ggatgacgtt tctaaaaata ttttaacaac ggtatttaat caactaatgg
    15661 aaaatcaacg aacagaatat attcaagcaa aagaatatga acgaacagaa aaccgacaaa
    15721 gtcaacgaaa tggctattat gagcgcagct ttacgacacg tgtaggcacg ctagaattaa
    15781 aagtacccag aacacgtgat ggccattttt cacccacagt gtttgaacgt tatcaacgaa
    15841 acgaaaaagc cctcatggct tcaatgttgg aaatgtatgt atcaggcgtt tcaactcgta
    15901 aagtatcaaa aattgtggaa gaactttgtg gtaaatccgt ctctaagtcc ttcgtttcta
    15961 gcttaacaga acagctagaa cctatggtta acgagtggca gaatcgttta ttatcagaaa
    16021 aaaattatcc ttacttaatg accgatgtac tctatataaa agtacgagaa gaaaatcgag
    16081 tactctcaaa aagctgtcat atagcgattg gaataaccaa agatggcgac cgtgaaatta
    16141 tcggcttcat gattcaaagt ggcgaaagcg aagagacctg gacaacattt tttgaatacc
    16201 taaaagaacg cggtttacaa ggtacggaac tcgttatttc tgatgcgcac aaaggattag
    16261 tctctgccat tagaaaatcc ttcaccaacg taagttggca aagatgccaa gttcacttcc
    16321 taagaaatat ctttaccacc attcctaaaa aaaattcaaa atctttcaga gaagctgtta
    16381 aaggaatttt taagttcaca gatattaact tagcgcgtga ggctaaaaat cgattgattc
    16441 atgattatat cgatcaacca aaatattcaa aagcttgcgc atcattggat gatgggttct
    16501 gttgcaaagt tttaaataaa gaataaaatc ccttacggta tctatgattt aagctgggat
    16561 tcccaataat accttgattt cagtacagac cgaaaacccg aagagagtgc cttcttttcg
    16621 ggttttctta tataatcctc gaatggcttc catgccttta atcgtggtag aggcagtgcg
    16681 taaacttcga tagaatttat tgcgtctctt tactggacga tggtcttgtt caatcaaatt
    16741 attcaggtat ttaatggtac gatgttctgt cccttgataa aagccgtatt cttttagttt
    16801 cttaaaggca cttgtaatag agggggcttt atctgtgact acaaccttcg gttcatcaaa
    16861 ctgcttcact aaccgcttaa gaaaagcata ggctgcttgt gtgtcccgtt ttttacgtaa
    16921 ccaaatatcc aaggttaaac catctgcatc gatggctcga tacaaataat gccattttcc
    16981 tttaattttg atgtacgttt catccatttt ccatgaataa aaggattttt tatttttctt
    17041 tttccaaatt tgatagagta gtttgccata ttcttgcacc caacgataaa tcgtcgtatg
    17101 agaaacgtta atgccacgat catataagat ttcttgaact tcacgatagc taaggttata
    17161 acgaagatag tagcccacgg ctacaataat cacatcctgc tgaaattgct ttcctttaaa
    17221 atgattcatc gtcattcctc ctgctatctt tttctattat tctaccttat ttgatagtag
    17281 atttaaaact ttgcaacaga accaattatc ttatcgtaga tatatattat aaatttaata
    17341 agaaagcgag gtgagaatcg tgaaaaaaac gatactaagt attttttcag tatttacaat
    17401 attaattggg ggctattttc ttttgaattt agattctgtt aattcaaacg ctcaaataaa
    17461 agatcaaaga gtagctgaac ataataataa aaaaatgagt ttgaccaaaa atatctattc
    17521 tatgtcagat gaagaattgt ataaagaatt tggtgattta tccggggaac agttagaaga
    17581 aagtattcca ggaattagtg actcagataa aattgttgtc ttgtctgctg gtgggcaatt
    17641 aatgggagat ggcaaatccg aattagttag ttataaacaa aatcacagac agtttattga
    17701 tgttaatact gattccaacg ctatttcgat taaggatcta aaagagcttt taaatagtaa
    17761 aagaaatgaa ttaaagcaga taaaagaaac taattcagtg gaattagagt aaaggaagat
    17821 tcattatgaa aaagattttt ggtgtttctg ttgggctact tatgatgtta acatttggaa
    17881 atgcagtata tgctgctgag aaagaagtta tttcagatcc agagcagtac gcctcacgat
    17941 actttgctga ttttgaagaa gaagataaag tacttgcatt gccagaaggt ggttttttaa
    18001 aaggggaagc taaaattgta tctatggata atccagatat aattcaaggt tcatataatt
    18061 cagaaactga tcctgcttca gtttcagtga cagaagcaaa aaaaattgtt gctgaaaaat
    18121 tcaaaaatga tattgaaact actccaatta tgcctcgagg agcatttcca cccgatgttg
    18181 gtactagcgg acaccttctt gtactagcag gaggaggaag ctataaatca cagccattta
    18241 gtggtgcggg atggcgtttt ggaggtatgg gtgtaaaacc agctgatggt acaggcaact
    18301 ttttacgttg gaaatcctac attgacgatg gaagagtagg aaatgtaaat caagccaacg
    18361 caactaaatc tggttctatt caaggaatgg cattgtatgc tcgtgaagga ttcaaatact
    18421 ttgcaccaaa cgggcctggt tggacaatga atataggtat ttattacact tataatcctg
    18481 ttgcaggtac gtattatgtt gttcaaaata tttaataaaa cagcacaaag agatttcttt
    18541 gtgctgtttt attattttta gttgttgaca aacactaaaa tataaaatat aatcaacaca
    18601 taaacgaacg tatgttcggc aagaaagcag gggattttta tggatgagat ggttttaagt
    18661 actcagaaat ggctaaacaa gaaatacagt aatgttacag ggtttgataa ggttccagaa
    18721 aatgggcgaa cagggtggcc tacaatctat ggacttattg aaggactaca agtagaactt
    18781 ggtattacta atctagtagc taattttgga cctaccactg aaaaaatgta cgataatcag
    18841 gttactccta aatggggcaa aaatctacct aaaaatattg tatttcttat tcaaggtgcc
    18901 ttttggtgta aggggattaa tccaggtggc ttcgatgggg tatatactcc atatttagat
    18961 actgctgtaa aagagttgca gactgatgca gggtttaatg gaagcgctgt aactggagtt
    19021 ttggatgcga aatgggccaa agcgttattt gatatgagtg cttttgttct tgttcccggc
    19081 ggagatagta aaattagaaa aatgcagcaa tggttaaatg taaattattt agaatacacg
    19141 ggaataatgc cttgtgatgg tatttatcaa agaaattcaa atcaagcatt aatttttgca
    19201 ttacaagctg aactaggata ttctcccagt gaagcaacag ggtcttatgg taatgggaca
    19261 actagtaaaa cttatcctgt gtctgaaggt aactcgggaa actatgtaag aataattcaa
    19321 tatggattat atgttaatgg ttattttgaa gacggtacat tcgatggtat tttcactaaa
    19381 tatatgggtt tagaagtact ggcattccga aaatttatgg tattgcctga atatactgaa
    19441 atagcagatg ttgttgtaat aaaaggacta ttgtctagcg ctggagatat tagaagatct
    19501 gcagatggcg cagatacttc tacgcaatta actagatctc aaatccaaac attggttgat
    19561 aatgatataa aaatagttgg tagatatctt actggtactg ttggaattgg aaaagatgaa
    19621 cgaaataagt atctaactac agaggaattg aataatattt tttctaaaaa tttatctgtg
    19681 tttcctatct atcaagatgg aggtgcagca ttagcttatt ttacttatga tcgtggctta
    19741 tcagatggta agaaggctat agatgcagca aaaaatctaa atataccatt aacaacagtt
    19801 atttattttg ctgttgatct agacatgtta ggggaagaaa ttcttgcata tgctggagaa
    19861 tattttaagg gggtatctgc tgtaatgtca tatagcgggt atcaaacggg tgtttacgga
    19921 acaagaaatg tttgttctca aataatcaat aacgggtatg cttcgtttgc atttgtttca
    19981 gatatgtcga ctggttatag tgggaattta ggttttccta tgcctagaca atggtctttt
    20041 gatcaatttg ttgaatttac cataggaagt ggcaacggag ctgttggtat cgatttaatc
    20101 gctacatcgg gtagagatag cggatttaat gagttatcaa atgatactaa taatgataat
    20161 tacattgcca aatacaatca gaaggttata aatcagatgg tacgtgcgta tcaatatcta
    20221 tcacaagctg gtcttgataa tccttggaac cctcatttga cattttatag atatgtaaat
    20281 tattctggtt tgtcatggga catcatttct tctcctgtaa cagagcatga tagaaaaatt
    20341 tatgatgaat ataggaataa attaactaat agcgagggcc tgtataatta ttttatagat
    20401 cctaatactg gttcaataat aggtttgcct cacttaattg tgacgttaca atcacagatg
    20461 tttctagccg acacaatcaa tgatagtgtt tctgactttg caggttggtt aggagattta
    20521 atgacttgct ggggtgaagt taagaaatta ggaatacaaa tggagcaagg tgtatttgca
    20581 ttagtaggta cggctgcagg tggaacattt agtctagaag atttatacca agatgttgac
    20641 gcggtaaatg tttatacctt agcaaaaaga aattctgatt caacagcttt atcggcttta
    20701 aaaacgtact attgtgataa gggtgctatt gatagattta atcaatttgt taagaacaga
    20761 tttggttctt cagataaaat cgcttcagta acaaatagtt tattagaaaa tgacgaaaca
    20821 gttgatatct taggtgtagg gataatttca tttttcattg ataaaatagt taataattca
    20881 cttgggacag attttactta tcttgatttt attggagatg aggggaaagt tgcaaatgga
    20941 ttttctgaaa aaattattca atttcaagaa aatagaagta aacttaatta agaatcgttt
    21001 actatttaaa cagtgtcctt ttccttttta aatatatacg ataaaataag tatatgaatt
    21061 gtaaaaggac atgatgatta tggaagaaat agaatggaat aatctgactc aaaataataa
    21121 aaataattct ggatgtggaa ttatctttat gtttgttata gttttgggaa tagtagtact
    21181 tttaataact gtcaagatag tagattactt tgcgaatact cctgaagaac aaatacagag
    21241 aaaacttcct gagtttgaaa gagtaccacc ttatgatcca agagataatt catttcaagt
    21301 aaaaaaatta aaagagtctc caaatgaaat gtggtttgaa gttacagttg aatcaagcga
    21361 cttcaaagaa aaaaagaaag aatacaatta tattgtaaag gcaaaagtat caaaaagatt
    21421 tatttttaac cctaaattag aaatatatag tgttgtaata gaataatagt gttaaaaaaa
    21481 ttgtaaaagt taaagaagtc aaattctgat gtgaaaaata aaatatacca tggaagacat
    21541 aaaagaaaaa ctggataact agtttattta atggcagacc gttaaggcct gccattttta
    21601 tgtattttag cggaataaat ataatcatgc gggagtgtaa acttactgtt tcaaaaagta
    21661 tactttttga catgccttga ttttctttgt ttatgtatgg cataataacc acataataca
    21721 atttgaaacg tttctgattt aatctgattg ttttgaaaca attttagtga aaaaagggta
    21781 gataaaaacg atgagaaaat ttttttatat ccgggtcagt agttatgatc aatcgatcga
    21841 acgacaactg atttccgcga aggaattagg aatccctgaa gaatatatat ttgtagaaaa
    21901 agccagcggc aaagatttta aacgccctga atatcaatta atgaaacgga tgtttcgaaa
    21961 aggagattta ctctatctac aatcattaga tagactaggc agaaataaac aaatgatttt
    22021 agaagaatgg cgagaattaa ctaaggaaaa gcagattgat atttctgtgt tagacatgcc
    22081 tctgttagat actgctagtt acaagcaact agatgggtta gagacgctta tctctgactt
    22141 aattctgcaa ttactcagct atatggccga agacgagcgg aaacgaatta atagccggca
    22201 aagagaaggc gtagaagctg cgaaacaaaa gggtgtaaaa ttcggcagaa agaaaattgc
    22261 tttacctcct gaatttcctg cgatctattc tgactggaaa gcaggaaaga taactgcagt
    22321 ctatgctatg gatcaattgg gcatgaaacg aaataccttt tatcgacggg tgaaagaata
    22381 tgaacatacc ttgcaccact tttcttgata gatataacag ctattagacg ggaagggaga
    22441 gtttgaaaat ggacttaacg aatcaaaggg tcgtttttac tggaacgctg cagcaaatga
    22501 cacgaaccca agccatcggt ttggttcact ctttaaacgg ccattgtcaa tcaagtgtta
    22561 cttcaaaaac aaatttcctg gtttgtggtc agtattctaa gtcgttgttt gatgattctc
    22621 tctatacaaa aaaggaacaa accgcgcggg acttgattgc gttaggtcat gagattacca
    22681 ttttatcaga agtcgaattt tatgcgttaa ttagtcaaca gttgaaagaa tggcaacggt
    22741 atttataatc gttagtaaaa tttacaagga ggaaaatttt tatgaagcga aaatcttatg
    22801 atcgttgggg cattgaaata actagtttta atcgaaatat tgcttttcac gtggagtgtg
    22861 actgtgggga attagcaaaa agtgtttatc aaaaaaatta cttttactgt cctaaatgcc
    22921 atcgccgata cggggtacat ggaacataga aacgaaatag tgcggtagaa aagcgaatga
    22981 atgtagtata tttctacaaa tcattcgctt tctttatttt ataaatagtt ggtcgagaga
    23041 tcccgttttc ttttgcaatc tctgcaactg gaatgccttg ctttaacatg tccaccacgg
    23101 ttttaaaaac taagcgtttt tgcggatctg ttgagttaat agaatactcg attggtcgtc
    23161 ccttatatcg gccggctttt tgagccaata atactccttg ccgctgacgt tcacgaattt
    23221 tctcacgctc gttttgtgca atataactta gcagtgataa aaacatatcg aacatagcgg
    23281 tatccaggag ttcatttcca gtattaaaat ctaaaaactg tgcatctaat atttttaacg
    23341 ctactttttt ctgtttcata aaagcaactg tattttttat atcttcataa tctcttccta
    23401 aacgatctag tgatgtaacg atgacgcaat caccttcacg gatataattt agtaattttt
    23461 gaaactcagg acgctcagta tctttaccac tggctttttc ttggaataat ttatcaatgt
    23521 taagtccttc catcattgcc aattgtcgat ccaaattttg atcttgtgaa gatactcgaa
    23581 tatagccaat ttttcccata aaaaactcct ttttaaaagt gatataattt acatgtaaaa
    23641 tttacttgta gttttactgc tatcatagca tttttaaaaa taaattttat gtagacttaa
    23701 aatttacttc atggagggtt taaatggatg aaatcaaaag taacaaaaaa gcatttggca
    23761 tttatttagg agaacctagt acagaacaat taaaccaatt tttttatttg catgaaaaag
    23821 atttagaatt gatggagact atacgacgac cagctactag attaggtttt gcactacagt
    23881 tagtctcact acgtttttta ggaactttta tattagatct taccaatatt ccccaaaatg
    23941 tattgagtta tgtagcaact caactaaata ttgatcctgg agaaattatc tactatagca
    24001 ggagacagac caggtatcag cacacaaaat tgataaaatc acattatgga tatcaagatt
    24061 tcaaccaacc ggaaatagaa acatacctag ctaactggct tttaaataga gcgctgtata
    24121 caacagaatc ttcagatatg ttgtttgata tgcttctaaa aaaatgtctg gatgaaaaga
    24181 ttgttttacc tggaattact actttttctc gttttgttgc tagtgcaatt gaaaaagctg
    24241 aagagcattt ataccgacaa ttgtctttgg ttccaactga agatgagaga aagcggcttc
    24301 tcaatcattt agaattaatt ggaactccag tttatggggc aataatcaaa atggacattt
    24361 tgagaacccc gttagctgac gatagtcata aagaaatagc cagaggtttt gaccgactaa
    24421 agcaatttca agctttctct actgaaaaat ggaagatgga atctattcct gaagggaaaa
    24481 taaaagttct tgcaaattat gcatttaaag ctaaagctca attaattcaa cgaatgagtg
    24541 aacagaaaaa actggcgttg ttagtggcat ttattttcat atacaaacgt aaggctatgg
    24601 atgaacaaat tttagcacta tctaattttt ttgaaactgt ttttagacgc gccaaaaata
    24661 aggaatctaa agaacgtctt cgtaccataa aagatctaga tcgagccgca tcgacacttt
    24721 cagatattgt agatttagta atgtccagtc attctgatac taatgaacta tcccttcgcg
    24781 atcgtatctt agaaaaatat tctgaggaaa atgttaccga agctgtatcg caagttcggc
    24841 tattggttaa aaatgatcgt gaaccaatag ccatttctga acttctgaac acttatcgaa
    24901 agttcagaaa atttattccg gatattttaa ctacactaac atttgacagc aatgactacg
    24961 gtaacaactg taaggaactc tggaccttca ttaataatag atttcctaag ccgattactt
    25021 acaaaatgtt tggagctatt aaacatactc ttccaaagaa atggatttat tacattcatg
    25081 aataccctga acaaactaat aaatgtgtat tgattgcagc tgtcgaattg ttaattcaat
    25141 ctttaaaacg ccatgatatt tatattcctc agagtgtctt atataacaat cctatggatt
    25201 gcttgattga tgagaaaact tgggttcaac aaaaatacgt tttattagaa caactagatc
    25261 ttccttcttc agcaaatgaa atgtctttat ggttaaagaa cgatttggaa ctgtcttata
    25321 aagaagcgct aaatcgttgg cctacttcta aaatggccag aatagaaaat gcagatcgcc
    25381 tggttgtctc tagacttaaa aagacatatg aaaaaaagga agataagtct tttagacgtc
    25441 gcattcagca gttacttcct aaaattgatt tgtcagattt gttattggaa gtaaaccaac
    25501 agttaaatct tactcaatca tttaaccact taagtgacaa ggacaccaaa atgaaagact
    25561 tggatattag tttattagca gttcttttat cagagtcctg caatattggt ttttccccgg
    25621 tttcaaaaga aggatttgat tctttaaagt atgatcgtct tgtctatgtc aatcatcatt
    25681 atattcgagt ggatacactt tcaggagcta atcaaaaaat aatacatgca cacaggaaac
    25741 ttgccacctc taagatatgg ggtgatgggc atatggcttc agctgacggt attcgttata
    25801 tcacaccaca acgttcccta tattctagaa gtaatccaaa atattttggc cgtggtcgtg
    25861 ggatcacatt ctacaatttt gtctctgatc aatatatagg gttccacgga atggtcgttt
    25921 cagggacact gcgagattcg ctttaccttc tagaaggatt cctcaatcaa cccagcgaat
    25981 taactcctaa tcagatcatg actgatacag ctggttatag cgatatgatt tttggtctct
    26041 ttggcttatt agggtttcaa tttagtccaa gaattgccaa tgataaagga accaaacttt
    26101 ggcgaatcga cgctaacgct cactacgggg aacttgatac gttgtctcaa aattcaatta
    26161 atatggaact gatttatacc cattgggagg acattcttag ggttgcaggt tcgttgaaat
    26221 ctggaaaagt gaatgcaaca gaattaacga aatctcttca acggaatggg caacccacgc
    26281 ctttaggaaa agcaataact gagtatggaa aagtttataa gacgaaacat cagcttcgtt
    26341 atatttctga cgaaatatat gcacggcaaa ttttagaaca attgaataag ggggaagctc
    26401 ggcatgcctt atgccgtaat attttttatg gacgaaaagg aaaactctac cagacttatt
    26461 atgatgggat ggaagagcag ctcaatgcat taggattagt tactaatgcc atcatatatt
    26521 ggaactcact gtatttagaa aaagtatttg aacaaatgaa agctgaagga ttcgactgtt
    26581 ccgaagaaat gatacgcagg caatctccac taattagtga tcacatcaat tttgttggta
    26641 agtatacgtt tagatacgaa gctgaattat ccaacggtaa gttacgtcca ttgaatgtag
    26701 aagaattcta gcaatgttcg ggttttgcat gctaccgcac tatttcgtat gactgttcca
    26761 gcgaatcact tcgaatagaa aaagagaaaa acacgagaac agcgttaaat caacgtttct
    26821 tgtgttttta cttttgtgct accgcactat ttcgtttcta tgttccatgt acccctttat
    26881 caagaagcgc aaacacgcca aattgccgat tggttgatcg gcatgaacgc aagcccttta
    26941 tataccttga atttacaaca aaaaggcgta caaggtacat tttcattagg acgtgtacaa
    27001 acaccgactt tatatctcat ttatcaacgc caggaagcaa tagaaaactt taaaaaagaa
    27061 ccttttttcc tgaataattc atagttttac taatagtctt tcctaacatt gatttaatag
    27121 tctttaaagg gttctgttgc aaagttttaa atctactatc aaataaggta gaataataga
    27181 aaaagatagc a
//
