LOCUS       NZ_CP072240             8944 bp    DNA     circular CON 16-MAY-2024
DEFINITION  Bacteroides uniformis strain CL06T03C05 plasmid pBuniCL06T03-1,
            complete sequence.
ACCESSION   NZ_CP072240
VERSION     NZ_CP072240.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN16451189
            Assembly: GCF_018291785.1
KEYWORDS    RefSeq.
SOURCE      Bacteroides uniformis
  ORGANISM  Bacteroides uniformis
            Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
            Bacteroides.
REFERENCE   1  (bases 1 to 8944)
  AUTHORS   Garcia-Bayona,L., Coyne,M.J. and Comstock,L.E.
  TITLE     Mobile Type VI secretion system loci of the gut Bacteroidales
            display extensive intra-ecosystem transfer, multi-species spread and
            geographical clustering
  JOURNAL   PLoS Genet 17 (4), e1009541 (2021)
   PUBMED   33901198
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8944)
  AUTHORS   Coyne,M.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2021) Department of Medicine/Division of
            Infectious Diseases, Brigham & Women's Hospital, 181 Longwood
            Avenue, Boston, MA 02115, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 20-OCT-2020
            Assembly Method                   :: FALCON-Unzip v. 1.2.0
            Assembly Name                     :: BuniCL06T03C05_pbv2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 282x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018291785.1-RS_2024_05_16
            Annotation Date                   :: 05/16/2024 04:04:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,736
            CDSs (total)                      :: 4,649
            Genes (coding)                    :: 4,532
            CDSs (with protein)               :: 4,532
            Genes (RNA)                       :: 87
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 37 of 117
            Pseudo Genes (incomplete)         :: 66 of 117
            Pseudo Genes (internal stop)      :: 31 of 117
            Pseudo Genes (multiple problems)  :: 15 of 117
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP072240.1.
            Sequencing by the Institute for Genome Sciences, Genomics Resource
            Center, School of Medicine, University of Maryland, 801 W.
            Baltimore Street, Baltimore, MD 21201, USA. Gene calling method:
            Prodigal version 2.6.3. Annotated using a custom modification of
            Prokka version 1.14.6.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..8944
                     /organism="Bacteroides uniformis"
                     /mol_type="genomic DNA"
                     /strain="CL06T03C05"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:820"
                     /plasmid="pBuniCL06T03-1"
                     /geo_loc_name="USA: Boston"
                     /lat_lon="42.3361 N 71.1075 W"
                     /collection_date="2009-05"
     gene            1..978
                     /locus_tag="INE83_RS22960"
                     /old_locus_tag="INE83_04631"
     CDS             1..978
                     /locus_tag="INE83_RS22960"
                     /old_locus_tag="INE83_04631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008669318.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_008669318.1"
                     /translation="MEKKDKKQRDIVLSQDNALTTARYKFDLIEKRALYSIIRNIRAQY
                     IENENGRRDLFDDLIITIHEEELKKCGDNTKMQNIYDALKRLRNRDIEINNEKMWLSIG
                     FVNYVKHIKNKSYFEVQVSKEVLPYYVELAQNFTSYSMTVAIALKSTFSQRFYELCCQY
                     RNAGFFFYTVEKLREMFMLEKKYKRGCDFKRRVLDDPQKELRELYNAGQCDLYFEFEPK
                     SYKGKEVTEYKFYVYTRQTEQQKLLEYESAKQAIIYITTTISRFSKSDKGYVKRVVNAV
                     QLHPEIAVQVAQKIQKKFEQYIDKPAKQIGAIIRVCLMEDFGIE"
                     /name="replication initiation protein"
     gene            992..1162
                     /locus_tag="INE83_RS22965"
                     /old_locus_tag="INE83_04632"
     CDS             992..1162
                     /locus_tag="INE83_RS22965"
                     /old_locus_tag="INE83_04632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_009276913.1"
                     /translation="MKTGDKVIVPAEINGYGRDLRAIVTEIEKFAGAIFVTVIFTEPCP
                     EACGRGGGCLP"
                     /name="hypothetical protein"
     gene            1287..1808
                     /locus_tag="INE83_RS22970"
                     /old_locus_tag="INE83_04633"
     CDS             1287..1808
                     /locus_tag="INE83_RS22970"
                     /old_locus_tag="INE83_04633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016271957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_008669313.1"
                     /translation="MEKGQESKQKRKTPLTTIAISQEYAKKLDEYLNGTGITRKEFVEL
                     SVDYFQRTGFDLRGEAFDLSPLEKVAGRLEQSAKIMERHNEGTEAVHLLLQAVREQTAK
                     QLPAPELIAHAAEEKAKAEAKSEEQEREIARLRSENSALLEYKEKAYRELCRIRDEQKT
                     IGKIKVNIEL"
                     /name="hypothetical protein"
     gene            1838..2380
                     /locus_tag="INE83_RS22975"
     CDS             1838..2380
                     /locus_tag="INE83_RS22975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005852953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="WP_080974082.1"
                     /translation="MKKFYLFILLPDYAAHEAVYFSQAITADDFAMKKNPKYVNKVVAP
                     TLEPISSIGGFRTLPDYSFDTMPDDYVALVLIGGFGWNTPVAEKVMPIIKSAIEQEKVI
                     GAICNAASFMAKCGIDRETTSKTLQKSSVIQKISVTLSSVIIAIIVCKLLIFNTLRLQQ
                     FFANHHFSGTYISSNSR"
                     /name="DJ-1/PfpI family protein"
     gene            2445..3500
                     /locus_tag="INE83_RS22980"
                     /old_locus_tag="INE83_04635"
     CDS             2445..3500
                     /locus_tag="INE83_RS22980"
                     /old_locus_tag="INE83_04635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008781140.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_215424929.1"
                     /translation="MIVMAMLAFFVFVSRYYVTCRNRQFEQSRWMIVVALLLFVVHYMC
                     QMRLGWRQQGNDVGVLFNLLFYSPSAILLSWSQLNILRAGHRRWSFMRYGVVGYALMVL
                     CIVAGVISNGSLHIGPMLYVADAIHFFTLLYYTWAPLRELGNVQRRLDSEHGNPADAYL
                     RTMRFGFFVVCAFAVISPLYILSRPLLFVFGPLGLISLSLFIVSFTALGFSMSEGVTEI
                     VTETNDEIAAAKVFREIGPERIAEIDMAVSKWRSEGGFRDSNLTLSSFARRIMVNRTDV
                     ASYLTSIYGKNFRTWLSGIRVEEAKALMAAHPEYSNEVVSMECGFSSRVYFQRLFKERT
                     GLTPAEWRRQR"
                     /name="helix-turn-helix domain-containing protein"
     gene            3720..5375
                     /locus_tag="INE83_RS22985"
                     /old_locus_tag="INE83_04636"
     CDS             3720..5375
                     /locus_tag="INE83_RS22985"
                     /old_locus_tag="INE83_04636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008669305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_008669305.1"
                     /translation="MQKTYLYLMVCVIGAMSLASCSEDSISPDAGGDGDGDSTTEVPLA
                     QVAKPKPNPWLAQEEYSITHFNSAQTDAFSSAVKDGTFNIDLSKCQMTWSGPVNLMTLA
                     STSPNYMWGMSSDRVSYLDISDGKLERVAEAGLPGITMKTQEQLTRIIADHATYDELSK
                     TVTDILGPVPQMSMANGNYVLCDKDNYAYTNAGQVMARYRLANPNNPKDGIMLDHQIRL
                     TNFTFGSFTLVGATMTYDGHLVVAAQNGLLVLNRALTTIEDSYPLPSDQILTNSICIDE
                     NGGVYVASNSRTPGGKGLMQKLICKDGKISTSQADGAWQAYYDGGPQAPCIKLGHGTGS
                     TPTLMGFGQDKDKLVVITDGSKRMKLVAFWRDEIPSDAQQVAGYDKRIAGVHEVTCGLG
                     TSTEWIQSEQSVVVGGYDAFVVNNINVTNQEINDKIIGVIAIGPIVKGPQGAECVRWNT
                     KEKKWESKWTRSDVSSVSMIPAVSIKSEMVFVCGWNDASGWEVTGLDWKSGATRHRSIL
                     GKNNRANGAYAIIQYLANGDLLFNSVAGPIRVKY"
                     /name="hypothetical protein"
     gene            complement(5930..6808)
                     /gene="btgB"
                     /locus_tag="INE83_RS22990"
                     /old_locus_tag="INE83_04637"
     CDS             complement(5930..6808)
                     /gene="btgB"
                     /locus_tag="INE83_RS22990"
                     /old_locus_tag="INE83_04637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007851393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mobilization protein BtgB"
                     /protein_id="WP_008669303.1"
                     /translation="MNVKIQGSGNGTYANTGSCVAVTNYLQHEDLERMKKGEEVQPFFN
                     QFRDYVSAREVTFKIDNNKAKLSRTDAKFYVITVSPSEKELRCMGRTPQECAEALRRYI
                     RQDVMRNYAEGFGKGLKSDDVEYYAKIHFNRDGESDSDMHAHIIVSRKDRSNTRKLSPK
                     TNHTGKKNCGNVKGGFDRTDFFRKCESSFDRRMGFDREPEESFDYLNAVKNGSPAEIAR
                     QVERAERIRKEKWDKLKAELQSRQEPEKSKNQQVEKTPDIEQPIPKKKQQEEDLELLKK
                     PKRSRGFGMGM"
                     /name="btgB"
     gene            complement(6805..7410)
                     /gene="btgA"
                     /locus_tag="INE83_RS22995"
                     /old_locus_tag="INE83_04638"
     CDS             complement(6805..7410)
                     /gene="btgA"
                     /locus_tag="INE83_RS22995"
                     /old_locus_tag="INE83_04638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007851392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mobilization protein BtgA"
                     /protein_id="WP_008669301.1"
                     /translation="MDKETTTSVTIDRKTFARLDRLAKSNNVSKKEFLSCALEYFEKYG
                     INPVEHESPAKEMQKLIKRCDQVIAFIRKQEQDFLRPACEAMGSTSMRVTMSMDSILTE
                     KKFSQYQKDNDLFMRDLASLAGIREQALDRAEKAVGQSRDMLLKNQQAIYARLDAVTQR
                     QEKIFSYIASYIDAKGKAGLFDDIKALYKNEKNKREKI"
                     /name="btgA"
     gene            7802..8149
                     /locus_tag="INE83_RS23000"
                     /old_locus_tag="INE83_04639"
     CDS             7802..8149
                     /locus_tag="INE83_RS23000"
                     /old_locus_tag="INE83_04639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007851390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_008669299.1"
                     /translation="MEAKSRFKVKLSNEAQEFLDGLPNKVREKIISNIRKSTFVLDPDL
                     FKKLDDTDIWEFRTFYNKTKYRLLAFWDKDDKINTLVIATHGFIKKTQKTPPKEIAKAE
                     EIRKDYFNSKR"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            8155..8469
                     /locus_tag="INE83_RS23005"
                     /old_locus_tag="INE83_04640"
     CDS             8155..8469
                     /locus_tag="INE83_RS23005"
                     /old_locus_tag="INE83_04640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007851388.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_007851388.1"
                     /translation="MEAKKFYTLEEIEDKYIGEKGTPKRDAYEEELNSFLIGEAIKQAR
                     QSKNLTQEELGNLIGVQRAQISRIENGKNLTFSTIARVFKAMGISAKLEIGSMGKVALW
                     "
                     /name="helix-turn-helix transcriptional regulator"
     Typing          2..978
                     /name="rep_cluster_1097"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.898"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(5934..6808)
                     /name="MOBB"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atggagaaga aagacaagaa acagagggat atagtcctgt cgcaagacaa tgcgctgact
       61 accgcacgct acaagttcga ccttatcgaa aaacgtgccc tatactccat tatacgaaat
      121 atccgggcgc aatacatcga gaacgagaac ggcagacggg acttattcga tgatctgatt
      181 atcaccatac acgaggaaga actaaagaaa tgcggtgaca ataccaagat gcaaaacatc
      241 tacgatgcgc taaaacggct tagaaatcgc gatatagaga ttaacaacga aaaaatgtgg
      301 ctaagtatcg gttttgtcaa ttacgtcaag catatcaaaa ataaatcgta ttttgaggtg
      361 caagtttcca aagaggtact accctattac gtggaactcg cccaaaactt cacgagttac
      421 tccatgacgg tagcaatcgc actcaaaagc acattctcgc aaaggtttta cgaactgtgc
      481 tgccaatacc gaaacgccgg gttctttttc tacacagtcg aaaagcttcg ggaaatgttc
      541 atgttggaaa agaaatacaa acggggatgc gatttcaaaa ggcgtgtact tgacgatccg
      601 caaaaggaac tccgggagtt gtacaatgcc ggacaatgcg atttatactt cgagttcgag
      661 ccaaagagct acaaaggcaa ggaagttacc gaatacaaat tctacgttta cacaaggcaa
      721 accgaacaac aaaagctatt ggaatacgaa agcgcaaaac aggcgatcat ctacataaca
      781 accactattt cgaggttctc taaaagtgac aaaggatatg ttaagcgtgt agtgaatgcc
      841 gtacagttac acccggaaat agccgtacag gtggcgcaaa agatacaaaa gaagtttgag
      901 caatatatag acaagccagc caaacagata ggggctatca tccgggtttg cttaatggaa
      961 gattttggta tagaataaaa aacatacaag tatgaaaaca ggtgataaag ttatcgtacc
     1021 agccgaaata aacggctatg gcagagattt acgggcaata gttacagaga tagagaagtt
     1081 cgccggggca atattcgtaa cagtgatatt caccgaacca tgtccggaag cctgcggaag
     1141 aggggggggg tgtttaccat gacttccagc taatagcaag gtgatttatt ttgctataat
     1201 cgcaataaat tgcaataata tctgtgataa attgctataa taatacttat aactaccttt
     1261 gcaacagaat atagcatttt acagcaatgg agaaaggaca ggaaagcaag caaaagagga
     1321 aaacaccgct taccaccata gcgataagcc aagagtacgc caaaaaatta gacgagtatt
     1381 taaacggtac gggtataact cgcaaagaat ttgtcgagtt gtccgttgat tatttccaaa
     1441 gaaccgggtt cgacctccgg ggtgaagctt ttgacctctc cccattagaa aaggttgccg
     1501 ggcggctgga acaatccgca aagatcatgg aacgacacaa cgaggggacg gaagcggtgc
     1561 acctgcttct ccaagctgtc cgggaacaga ccgccaagca actcccagcg ccggaactga
     1621 tcgcccatgc tgccgaagaa aaagcaaagg cagaagccaa aagcgaagaa caagaaaggg
     1681 agattgcccg gctacgctcc gaaaactccg ctttgctgga gtacaaagaa aaggcatacc
     1741 gggaactatg ccggatacgt gatgaacaaa aaaccatagg gaagataaaa gtaaatatag
     1801 agttataaaa gaacatttat aaataaaaaa atcatgaata aagaaatttt atttatttat
     1861 ccttttgccg gattatgcag cacatgaagc tgtgtacttt tcacaggcta ttacagctga
     1921 tgattttgcc atgaaaaaaa atccaaaata tgtcaataag gttgtcgcac ccaccttaga
     1981 accaataagt tcgattggtg gattccgcac attacccgat tattcgtttg acacaatgcc
     2041 tgatgattat gtagcattgg tattaattgg cggttttggt tggaatacac ctgttgcaga
     2101 aaaggttatg ccaattatta aaagtgctat tgaacaagaa aaggttatag gtgcgatttg
     2161 taatgcagct tcattcatgg ctaagtgtgg tattgaccga gaaacaacat caaaaacttt
     2221 gcagaagtca tccgtaatac agaaaatctc agtaactttg tcctcggtaa tcatagcaat
     2281 tattgtctgt aaacttttga tatttaacac tctaagatta caacaatttt tcgctaatca
     2341 ccatttttca ggcacttata tttcgtcgaa ctcacgttaa attatttaat atacatacaa
     2401 tcttggatac ttgcttagac cttattgctc ttcaatatac ttgcatgatt gtgatggcca
     2461 tgcttgcatt ttttgtgttt gtgtcgcgct actatgtaac ttgccgtaac agacagtttg
     2521 agcagtcgcg ttggatgatt gttgtggcat tactattgtt tgttgtacac tacatgtgtc
     2581 agatgcggtt gggttggcga caacagggga acgatgtggg tgttctgttt aatctgctgt
     2641 tttattcgcc ttcggctatt ttgttgtcat ggtcgcagct taatattctg cgcgctgggc
     2701 atagacgttg gagttttatg cgctatggcg ttgttggata tgctcttatg gtattgtgca
     2761 tagtcgcagg tgttatttca aatggcagtc tgcatattgg tcctatgcta tatgttgctg
     2821 atgctattca tttctttact ctattgtatt atacatgggc accgctgagg gaacttggta
     2881 atgttcaacg tcggctcgac agtgaacatg gtaatcctgc agatgcctac ctgcgcacta
     2941 tgcgctttgg tttttttgtg gtgtgtgctt ttgctgtaat ttcgcctctt tatatattgt
     3001 cgcggccgct gctctttgtc tttggacctt tgggattgat ttcgctttcg ctgtttattg
     3061 ttagttttac ggcgcttgga tttagtatgt ccgagggagt aactgagatt gttaccgaga
     3121 ctaacgacga gatagccgct gctaaagtct ttagggagat tgggcctgag cgtattgccg
     3181 aaatagatat ggcggtaagc aaatggcgaa gcgagggcgg ttttagagat agcaacttga
     3241 cattatcctc gtttgctcgt cgcataatgg ttaatcgtac cgacgttgct tcgtatctga
     3301 cttccatata tggtaagaat ttccgtacat ggctttcggg tattcgcgtg gaggaggcaa
     3361 aggcactcat ggctgcacac cccgaatata gtaacgaggt tgtttctatg gagtgcggtt
     3421 tctcgtcgcg tgtgtatttt cagcgtctgt tcaaggaaag gacgggcttg actcccgccg
     3481 agtggcgccg tcaacggtaa tatactggtt atgtgtgcgt ttgctactga atgtaaggtg
     3541 taacttttgt acgaaggtta cataataagg caaagtgtaa cctttcttac tgtgacgtat
     3601 cctttctata agagtgacac acaagtgatg tctttgaggt ttttgatggt tgatgctcct
     3661 gtatctttgc atgaggaaat tcaaactatt caaatataaa ttctcaaaaa caattcacta
     3721 tgcaaaaaac ctatctttat ttaatggtgt gtgtcatagg ggctatgtct ttagcttcgt
     3781 gttccgaaga ttctatttct cctgatgctg gtggcgatgg cgatggcgac agcactaccg
     3841 aagtgccttt ggcacaagtt gcaaaaccca aacctaaccc ttggcttgca caggaagagt
     3901 atagtattac gcacttcaat tcggctcaga ctgatgcttt ctcgtctgct gtcaaggatg
     3961 gaactttcaa tatcgatctt tccaagtgtc agatgacatg gagcggtcct gttaatttga
     4021 tgactcttgc ttcgacttcg cccaattata tgtggggtat gagtagcgac cgcgtgtcgt
     4081 atcttgacat aagcgacggc aaacttgaaa gggttgccga ggctggcttg ccagggatta
     4141 caatgaagac ccaggagcaa ctgacacgta taattgccga tcatgctact tacgacgaac
     4201 tttccaagac ggttaccgat atattgggtc cggtgccaca aatgtctatg gccaacggta
     4261 attatgtctt gtgcgacaag gataactatg cttacaccaa tgcaggtcag gtaatggcac
     4321 gctatcgcct tgccaatcct aataatccca aggatggtat catgttggat catcagataa
     4381 gacttacgaa ttttaccttc ggctctttta cactcgtagg cgctactatg acctatgacg
     4441 gacaccttgt tgtggctgct cagaacggac ttcttgtgct gaatcgtgct cttactacaa
     4501 tcgaagattc ataccctctt ccatcagacc agattctcac caactctatc tgcatcgacg
     4561 agaatggcgg tgtttacgta gcaagtaaca gccgcacacc aggcggaaaa ggccttatgc
     4621 agaaactcat ctgcaaggac ggcaaaatct ccacctccca ggctgatggt gcatggcaag
     4681 cctattacga cggtggtccg caagcaccat gtatcaaact cggacatggc actggttcaa
     4741 cgcctacact tatgggcttt ggccaagaca aggacaagct ggtagttatt accgatggct
     4801 ctaagcgtat gaaactggta gctttctggc gtgacgaaat cccctcagac gcacagcaag
     4861 tggcaggata cgacaagcgt atagccggag tgcacgaggt tacatgtggt cttggaacat
     4921 caacagagtg gatacagtct gagcagtctg ttgtagtagg cggctatgac gcctttgttg
     4981 taaacaatat taatgttacc aatcaggaaa taaacgacaa gattattggt gtaatcgcta
     5041 ttggtcctat tgtcaaaggc cctcaaggtg ccgagtgtgt acgttggaat acaaaggaga
     5101 aaaagtggga gagtaagtgg acgcgcagcg atgtaagttc tgtaagtatg attcctgccg
     5161 taagtatcaa gtcagagatg gtatttgtat gtggctggaa cgatgcttcg ggctgggaag
     5221 ttacaggact tgactggaag agtggtgcca cacgtcaccg cagcatattg ggcaagaaca
     5281 accgagccaa tggtgcctac gccatcattc agtatcttgc taacggcgac cttttattca
     5341 actctgttgc cggaccaatc cgcgtaaaat attgagataa tttaatcatc atataacagt
     5401 tatgtcaata cttcactaaa aaattaccga agtattgtaa tgacacaccc gaacatattg
     5461 aaatgttcta tcagttccat aaacaaggct tctgttcttt attcctagat acaggtgata
     5521 aataacagat aagaaacaga ttataacaag cctccggcgg ggttttcgct gggggctttt
     5581 gacctttgca catataaaaa gcaaaaagaa agcgatatcg gagcgtatac cataaaacag
     5641 accaccgact attacaaaac gatattacgt gcctaactga tcggggcagt tcctccacca
     5701 tgcggacaaa tcccggtaac aaaatgacaa aacggacact caccaaagaa caacattttt
     5761 ttcttttttc ctaaacacct tccagcgaag cacagtgtat ttgtcaaggg cgaagggtaa
     5821 aaaataccgc acgagcgaag cgagcacagg agatttttta cccggagagt gaaacgtccc
     5881 tttacaaatg cggcgtgcgg agttaccttt gtgccggaaa atagaaaaat cacatgccca
     5941 ttccgaaacc tctgctcctt tttggcttct tcaggagttc cagatcttcc tcctgctgct
     6001 tctttttggg aataggctgc tcgatgtccg gcgttttctc cacctgttga tttttcgact
     6061 tctccggctc ctgccgggat tgaagctctg ctttgagttt gtcccatttc tcctttctga
     6121 tgcgttccgc acgttccacc tgccgggcta tttccgccgg acttccgttc ttgacggcat
     6181 taagatagtc gaagctttcc tccggctccc ggtcaaaccc catgcgccga tcaaaagagc
     6241 tttcacactt ccggaaaaaa tccgtccggt caaaacctcc cttcacgttg ccgcagttct
     6301 tcttcccggt gtggttcgtt ttagggctta acttcctggt gttgctccgg tctttccggc
     6361 tgacgatgat atgtgcgtgc atatcgctgt cactttcacc gtcccggttg aaatggatct
     6421 ttgcataata ttccacatca tcgcttttca agccttttcc gaagccctcc gcatagtttc
     6481 tcatcacatc ctgccgtatg taccgccgta aggcttccgc acactcctgc ggagttctgc
     6541 ccatgcagcg cagctccttc tctgaagggc tgacagtgat aacatagaac tttgcgtcag
     6601 tccggcttaa cttagccttg ttgttgtcta tcttgaatgt gacctccctt gcgctcacgt
     6661 agtcccggaa ctggttgaag aacggctgca cctcctcccc tttcttcatc ctctccaaat
     6721 cctcatgctg gagatagttc gtcaccgcaa cacaactgcc tgtattggca tatgtgccgt
     6781 taccgcttcc ctgtatcttc acgttcatat cttttccctt ttgttcttct cgttcttgta
     6841 caaggctttt atatcatcga aaagcccggc ttttcctttc gcatcgatat agcttgcgat
     6901 ataggagaag atcttctcct gcctttgcgt cacagcgtcc agccttgcat aaatggcttg
     6961 ttggttcttc agaagcatat ccctcgactg accgactgcc ttttccgccc ggtccaaagc
     7021 ctgctccctt atcccggcaa ggcttgcaag gtcacgcatg aataggtcat tgtctttttg
     7081 gtattggctg aacttttttt ccgtaagtat cgagtccatg ctcatggtca ctctcatgct
     7141 tgtactgccc atggcttcac aagccggacg caagaaatcc tgctcctgct ttctgatgaa
     7201 cgctatcacc tgatcacagc gtttgataag tttctgcatt tcctttgccg gactctcatg
     7261 ctcaaccggg ttgatgccgt acttctcgaa gtactccagc gcacaggaaa ggaactcttt
     7321 ctttgataca ttattggact ttgccagcct atcaagccgg gcaaacgttt ttcggtcaat
     7381 ggtgacagaa gtggtggttt ccttatccat acaattgcgg ttttaattgc tgtttatatt
     7441 attaaatctc tgatttccaa aggtatgatt ttaaccacaa tttcaaacta attgcggtta
     7501 aaaaacttaa acggctgata ttcagccgta accccgtagg gcaagaggaa aaacagggta
     7561 aagcccggtt tcctcttgct attctttcga ctgccgagca atcgacgaac accctcccct
     7621 gcggtacggc gaaagctcgt acaaggggga cggggagaag tcggagcgag gcacaaagaa
     7681 agaacctatt ccacaaacaa aaaaacacat caaaacggca caacaggctg cataaaatat
     7741 caatattttg tttcgctata tggaaacaaa atattatctt tgcaacacta aaaaacttta
     7801 tatggaagca aaatcaagat tcaaggtcaa attatccaac gaagcccaag agtttttaga
     7861 cggattgccc aacaaggtac gtgagaagat cattagcaat attcgtaaat ccacctttgt
     7921 acttgatcca gatttattca agaaattgga tgatacggat atttgggaat tcagaacgtt
     7981 ctataacaaa accaagtaca ggcttcttgc tttttgggat aaggacgata agataaacac
     8041 tctggtaatc gcaacacatg ggtttatcaa gaaaacccaa aagacacctc ccaaagaaat
     8101 agccaaagcc gaagagatta gaaaagatta ttttaattca aaaagataaa gcgtatggaa
     8161 gcaaagaaat tttatacact cgaagaaatc gaggataaat acatcggaga aaaaggtact
     8221 cccaaacgtg atgcctacga agaagaactt aactcttttt tgataggtga agccattaaa
     8281 caagctcgcc aatcaaagaa cttaacccaa gaggaattag gtaatctgat aggagtgcaa
     8341 cgggctcaaa tctcccgaat tgaaaacggt aagaatttaa ccttttccac cattgcaaga
     8401 gtttttaagg ctatggggat aagtgctaaa cttgaaatcg gaagcatggg taaagttgcg
     8461 ttatggtaac taactataca acaaaaagtt acattaaatc cgggatgcgt tttcgctccc
     8521 ggaaacttct tgttttatac attaaaagtc atatttatac aaaatttaac acgccaaaaa
     8581 atcttcctaa tccgttgcac ttggctttac ttgtttccac tctctcccat tctccggaaa
     8641 ttcgtcgtat caaaaaacac gctgaaaagt ggagcgaagc gacctctata aaccaaaaaa
     8701 gaaacactcc attgctttac ggtaattttt agtttctttt tagttacttt tacggcatag
     8761 cataacacat tgtgctgtaa tatcttacaa aggtcatcta cgacaaattt ccgagcatct
     8821 acgacaaatt tccgagcatc tacgacaaat ttccgaaaaa aacggttatc tacgacaaat
     8881 attctacgcc atatatttgt ttttgtcgta gataaatatt tcctttgcga aaagcattaa
     8941 agtc
//
