LOCUS       NZ_CP072222             6108 bp    DNA     circular CON 07-APR-2024
DEFINITION  Bacteroides uniformis strain CL11T00C07 plasmid pBuniCL11T00-2,
            complete sequence.
ACCESSION   NZ_CP072222
VERSION     NZ_CP072222.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN16451196
            Assembly: GCF_018289175.1
KEYWORDS    RefSeq.
SOURCE      Bacteroides uniformis
  ORGANISM  Bacteroides uniformis
            Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
            Bacteroides.
REFERENCE   1  (bases 1 to 6108)
  AUTHORS   Garcia-Bayona,L., Coyne,M.J. and Comstock,L.E.
  TITLE     Mobile Type VI secretion system loci of the gut Bacteroidales
            display extensive intra-ecosystem transfer, multi-species spread and
            geographical clustering
  JOURNAL   PLoS Genet 17 (4), e1009541 (2021)
   PUBMED   33901198
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6108)
  AUTHORS   Coyne,M.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2021) Department of Medicine/Division of
            Infectious Diseases, Brigham & Women's Hospital, 181 Longwood
            Avenue, Boston, MA 02115, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 20-OCT-2020
            Assembly Method                   :: FALCON-Unzip v. 1.2.0
            Assembly Name                     :: BuniCL11T00C07_pbv2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 271x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018289175.1-RS_2024_04_07
            Annotation Date                   :: 04/07/2024 07:52:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,676
            CDSs (total)                      :: 4,583
            Genes (coding)                    :: 4,499
            CDSs (with protein)               :: 4,499
            Genes (RNA)                       :: 93
            rRNAs                             :: 5, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 78
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 29 of 84
            Pseudo Genes (incomplete)         :: 49 of 84
            Pseudo Genes (internal stop)      :: 22 of 84
            Pseudo Genes (multiple problems)  :: 14 of 84
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP072222.1.
            Sequencing by the Institute for Genome Sciences, Genomics Resource
            Center, School of Medicine, University of Maryland, 801 W.
            Baltimore Street, Baltimore, MD 21201, USA. Gene calling method:
            Prodigal version 2.6.3. Annotated using a custom modification of
            Prokka version 1.14.6.
            Bacteria available from Dr. Laurie Comstock, Brigham & Women's
            Hospital, 181 Longwood Avenue, Boston, MA 02115 USA.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..6108
                     /organism="Bacteroides uniformis"
                     /mol_type="genomic DNA"
                     /strain="CL11T00C07"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:820"
                     /plasmid="pBuniCL11T00-2"
                     /geo_loc_name="USA: Boston"
                     /lat_lon="42.3361 N 71.1075 W"
                     /collection_date="2009-05"
     gene            1..981
                     /locus_tag="INE90_RS22605"
                     /old_locus_tag="INE90_04548"
     CDS             1..981
                     /locus_tag="INE90_RS22605"
                     /old_locus_tag="INE90_04548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007844269.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_117894003.1"
                     /translation="MAIKITNKDVIQSYLMTVSKYDFSVYEKRILYRLVEAMQCEIEGK
                     KLYPGLRIEKTLYDDRVVLMPISAFLANDDDENYTRVKKALLDLRNKSFEFDDGQIWKV
                     IGIIEKPQFNYKRGWVRFEIQPEVYNAVLNFSKGFRKYELKTAMEFTSQYSMRFYELMS
                     GQERPLIYTIEDLKIMFGVQDKYKRNPDFIKRIIVPAKEELDAKSPYSFEYKILKEGRS
                     FHSLKLYPKYQPEHRDEELEKHELQKQVSLGWDLDRLIRNYLKQELLFTDQEIRNNIDL
                     FRDAQKKLDLMLELSTLKGKSRDKKNPKGYIINALKGKVKDKEEL"
                     /name="replication initiation protein"
     gene            1012..1212
                     /locus_tag="INE90_RS22610"
                     /old_locus_tag="INE90_04549"
     CDS             1012..1212
                     /locus_tag="INE90_RS22610"
                     /old_locus_tag="INE90_04549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005812761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_211475970.1"
                     /translation="MKEGDLILVSAEATGLGKPMEAVIDKIETFMEQTLVTVTYTRPDA
                     LSGFGGCFVDSHITLSKEKAK"
                     /name="hypothetical protein"
     gene            1326..1874
                     /locus_tag="INE90_RS22615"
                     /old_locus_tag="INE90_04550"
     CDS             1326..1874
                     /locus_tag="INE90_RS22615"
                     /old_locus_tag="INE90_04550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013619583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BfmA/BtgA family mobilization protein"
                     /protein_id="WP_172685631.1"
                     /translation="MTDKVTIQPKSKPEKTTISISGETSERLEIYCRANGILRKEFVSL
                     ALEYFERTGFDLKSNALDYSPLEKIIGELNEVKATMQTSNEGTEAIRQLLQAVREQTAK
                     QLPAPELIAKAAEEKVRAEMKSEEQAKELQVLQEENDRLRNEIKVLQEYKEKAHRELCR
                     VRDEQKTFGKIKVKTEFNL"
                     /name="BfmA/BtgA family mobilization protein"
     gene            1893..2846
                     /gene="bla"
                     /locus_tag="INE90_RS22620"
                     /old_locus_tag="INE90_04551"
     CDS             1893..2846
                     /gene="bla"
                     /locus_tag="INE90_RS22620"
                     /old_locus_tag="INE90_04551"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_057280848.1"
                     /GO_function="GO:0008800 - beta-lactamase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase, subclass A2"
                     /protein_id="WP_211475971.1"
                     /translation="MKKNKIILSVSIVILLCLTIISLKQFSHKSIANKSKSELNSQVIS
                     DSISKIASEYPGEIGVAVIINNQDTVTVNNKSIYPMMSVFKVHQALALCNDFDKKGISL
                     DTLVKINREKLDPKTWSPMMKDYSTSVLSLTVRDLLRYTLIQSDNNASNIMFKNMLNTA
                     QTDSFIAKLIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAILMNRLFTESLISNEKQ
                     NFIKNTLTECKTGVDRIVAPLLDKEGVVIAHKTGSGHVNENGILAAHNDVAFIRLPNNK
                     HYTLAVFVKDFKGNEKQAAKIIARISGTVYSLLIQF"
                     /name="bla"
     gene            complement(2953..3555)
                     /locus_tag="INE90_RS22625"
                     /old_locus_tag="INE90_04552"
     CDS             complement(2953..3555)
                     /locus_tag="INE90_RS22625"
                     /old_locus_tag="INE90_04552"
                     /inference="COORDINATES: protein motif:HMM:NF040155.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5712 family protein"
                     /protein_id="WP_249931797.1"
                     /translation="MRKYVRDDVMQHYAEGFGKGLNKEDIEYYGKIHFERKGADRYDMH
                     AHIIVSRKDRSNTRKLSPKTNHTGKKNCGNVKGGFDRTDFFRKCESSFDKRTGYDRAPE
                     QTFDYLNTMKNGSPKEIFQKKEWAERVNHERLEKMKAEWSRDLQEPHQEQGREESQQQG
                     NSISQVPEINQAPQRKKQQEEELDQPRKKSRGFGMGM"
                     /name="DUF5712 family protein"
     gene            complement(<3617..4027)
                     /locus_tag="INE90_RS22630"
                     /old_locus_tag="INE90_04553"
                     /pseudo=""
     CDS             complement(<3617..4027)
                     /locus_tag="INE90_RS22630"
                     /old_locus_tag="INE90_04553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008782579.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5712 family protein"
                     /name="DUF5712 family protein"
     gene            complement(4024..4626)
                     /locus_tag="INE90_RS22635"
                     /old_locus_tag="INE90_04554"
     CDS             complement(4024..4626)
                     /locus_tag="INE90_RS22635"
                     /old_locus_tag="INE90_04554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013619580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BfmA/BtgA family mobilization protein"
                     /protein_id="WP_211475969.1"
                     /translation="MEKDSKTTVAVERTTFTKLDRLAKANNVSKMEFLTHAINYFEKYG
                     INPVEHESPAQEMQKLIKRMDQVFAFLKKQETDLVRPACEALAGASTQITINLSSLLSE
                     EKFRRFLKENSELFIEVMNQSSEKGKAIDRAERAVRDSDATIRKNQQAIFKRIEANETA
                     QLKAMQHIVSFLDAKGKTGLLDDINKVYEREKERRGL"
                     /name="BfmA/BtgA family mobilization protein"
     gene            complement(5117..5386)
                     /locus_tag="INE90_RS22640"
                     /old_locus_tag="INE90_04555"
     CDS             complement(5117..5386)
                     /locus_tag="INE90_RS22640"
                     /old_locus_tag="INE90_04555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018967844.1"
                     /GO_process="GO:0008219 - cell death [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="WP_032530137.1"
                     /translation="MYEIEFSKEAVKHVLLMRKSSPQLFKKLEKLLDELREHPYTGTGH
                     PEQLRYLEGVWSRQLDKKNRIRYMVNETTVIVFIISAWGHYDDK"
                     /name="Txe/YoeB family addiction module toxin"
     gene            complement(5379..5645)
                     /locus_tag="INE90_RS22645"
                     /old_locus_tag="INE90_04556"
     CDS             complement(5379..5645)
                     /locus_tag="INE90_RS22645"
                     /old_locus_tag="INE90_04556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008671564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prevent-host-death protein"
                     /protein_id="WP_149938367.1"
                     /translation="MQIVTTREFRANQKKYFEMAETETILISRRNAAPIMVCAVREGDF
                     PSKEELAAIQRGIDDVRNGNTFRMAKNESLDDFLNRIEGEGNV"
                     /name="prevent-host-death protein"
     Typing          2..981
                     /name="rep_cluster_1085"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.675"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(2957..3612)
                     /name="MOBB"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="98.174"
                     /coverage="100.0"
                     /evalue="2.66e-134"
     Typing          complement(3615..4027)
                     /name="MOBB"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="2.88e-86"
ORIGIN
        1 atggctataa aaataacaaa caaagatgtg atacagagct atttaatgac tgtatctaag
       61 tatgattttt cagtgtacga aaaacgcatt ctgtacaggc ttgtggaagc aatgcagtgt
      121 gagatagaag gtaagaagct ttatcctgga ctacgtatag aaaagacgtt atacgatgat
      181 agagttgttt taatgcccat ttctgcgttt ttagccaacg atgatgacga gaactacacc
      241 cgtgtcaaaa aagcactgtt agaccttaga aataagtctt ttgagttcga tgatgggcaa
      301 atatggaagg tgataggtat tatcgagaag ccacaattca attacaaaag aggctgggta
      361 agatttgaaa tacaacctga agtatataat gccgtactta atttttcaaa gggcttcagg
      421 aagtatgaac ttaaaacggc catggagttt acaagtcagt actcgatgcg tttctatgaa
      481 ctcatgagtg gtcaagaaag gcctttgatt tacaccatag aggatctaaa aatcatgttt
      541 ggtgtacagg acaaatacaa acgtaatccg gatttcataa aaagaatcat agttccagct
      601 aaagaagaac tggacgcaaa aagcccatat tcgtttgaat acaaaattct gaaagaaggt
      661 cgttcttttc attcactgaa gctgtatccc aaataccaac cggaacacag ggatgaagaa
      721 cttgaaaagc acgaactaca aaaacaggtc agtctgggct gggatctgga caggctcata
      781 agaaactatc taaaacaaga gcttcttttc acagaccagg aaataagaaa caacatagac
      841 cttttcaggg atgcacagaa gaaacttgat ttaatgctgg agctttcaac cctgaaggga
      901 aaatcaaggg ataaaaagaa ccctaaaggg tatataataa acgcactgaa gggaaaagta
      961 aaagacaagg aagaactttg attatgttac acaatcaaaa aaaacaacga tatgaaagaa
     1021 ggagatttga tattggtatc tgctgaagcc acaggcttag gaaagccaat ggaagccgtt
     1081 atagacaaga ttgaaacatt catggaacaa acccttgtaa cggtcactta cacgcgacca
     1141 gacgccttat ccggcttcgg agggtgcttt gtggattctc atatcacttt aagcaaagaa
     1201 aaggccaagt aacctgaata tatttcagga atattcagta tatttacagc atatttaatt
     1261 aaaaagaagc ataaaaccag catatcaagc atattataag catatttata tcaatcggtt
     1321 aaggtatgac agataaagta accatacaac ccaaaagcaa gccggaaaag actacaatct
     1381 caataagcgg agaaacatct gaacggctgg agatatactg ccgggcaaac ggcatattac
     1441 ggaaagagtt cgtttctctc gccctggaat actttgaacg cacaggtttc gacctgaaga
     1501 gtaacgcact tgattactcc cccttggaaa agatcatcgg agaattgaat gaagtaaaag
     1561 cgaccatgca gacaagcaat gagggaacag aagcgattcg ccaactacta caggcagtcc
     1621 gggaacagac cgcaaaacag cttccagctc cagaacttat cgcaaaggca gcagaagaaa
     1681 aggtacgtgc tgaaatgaag tctgaagaac aggctaaaga gctccaggtt cttcaggaag
     1741 aaaacgaccg attgcgtaac gaaatcaaag ttcttcagga gtataaggaa aaagcacacc
     1801 gggaactttg ccgagtacgt gatgaacaga aaacattcgg gaaaataaaa gtaaaaacag
     1861 aatttaattt ataactctat atcatttatt tcatgaaaaa aaacaagatt attttatcag
     1921 tttcaattgt cattttattg tgtttaacta tcatttcatt aaagcaattt tcgcacaagt
     1981 caatagcgaa caagagtaaa tcagagctaa acagtcaggt tatcagcgat tctatttcta
     2041 agattgcatc cgaatatcca ggagaaatcg gagttgctgt aatcataaac aatcaggaca
     2101 cagtaacagt aaacaacaaa agtatttatc caatgatgag cgtatttaag gttcatcagg
     2161 cattagctct ttgcaatgac tttgacaaaa aaggtatttc ccttgacaca ttggtaaaga
     2221 taaataggga aaaacttgat ccaaaaacgt ggagccctat gatgaaagat tattcaacat
     2281 ctgtcttatc gttaacagtg agagatttat tacgttatac tcttattcaa agcgacaata
     2341 atgcaagcaa tatcatgttt aagaatatgc tcaatactgc acaaacagac agttttatag
     2401 cgaaactcat tccacgttcg agctttcaaa tagcttacac ggaagaggaa atgtcagctg
     2461 accatgacaa agcttactct aattatacat ctcctcttgg tgccgcaata ttgatgaatc
     2521 gtttgtttac agaaagcctt attagtaacg agaaacaaaa tttcattaaa aatacattga
     2581 cagaatgtaa aacaggtgtg gacaggatag tagctccgct tcttgataaa gaaggggttg
     2641 ttatagcaca taagacaggc tcaggtcatg tcaatgaaaa tggtattctt gcagctcaca
     2701 atgatgtagc ctttatacgt ttacctaata acaaacacta tacattggct gtattcgtaa
     2761 aggatttcaa gggtaatgaa aaacaagctg caaaaatcat agcccgcata tccggcactg
     2821 tatattcatt attgattcaa ttttagggaa acaaaaaaag cttttccaag aactagttgt
     2881 taattccctt accctgcata tcaaagtaag ggaattaaca agccctaaca caagcggtat
     2941 gtatatgtag aatcacatac ccattccaaa accccggctt tttttcctgg gctggtcgag
     3001 ttcttcctcc tgttgcttct tccgctgtgg cgcctggttg atttccggaa cttgggaaat
     3061 actgtttccc tgttgttggc tctcttcccg gccttgttcc tggtgcggtt cctgaagatc
     3121 ccggctccat tcggctttca tcttctcaag ccgttcatgg ttcacacgtt ccgcccactc
     3181 ctttttctga aatatttctt tcgggcttcc gttcttcatg gtattgagat agtcgaaggt
     3241 ctgttccggg gcccggtcat accctgtgcg cttgtcaaat gaagattcac actttcggaa
     3301 aaaatctgtc ctgtcaaaac ctcccttcac gttcccgcag ttcttcttcc cggtgtggtt
     3361 ggtctttggg cttaacttcc tggtgttgct cctgtccttc cggctgacga tgatatgtgc
     3421 gtgcatgtcg taccggtcgg ctcccttcct ctcgaaatgg atttttccgt aatactcgat
     3481 atcctctttg ttcaagcctt ttccgaaccc ttccgcatag tgctgcatca catcatcacg
     3541 gacatacttt ctcatggctt cagcctgttc cttctcggtc ttgcccattt tctccagctc
     3601 ccggctggaa gggcgctccc ttcctctcga aatggatttt tccgtaatac tcgatatcct
     3661 ctttgttcaa gccttttccg aacccttccg catagtgctg catcacatca tcacggacat
     3721 actttctcat ggcttcagcc tgttccttct cggtcttgcc cattttctcc agctcccggc
     3781 tggaagggct taccgtgatc acatagaact tcgcatcgtt ccggcttaat tttgccttgt
     3841 tgttgtctat cttaaaggtt acttcctgtg cgcttatata gtcacgtgag ttattgaaaa
     3901 acggctgcac ttcccggccg ttcttcatgc gctccagatc ctcatgctgg aggtaggtcg
     3961 ttactcctgt gcagctccct gtattggcat aggtcccgga accgccaccc tgaattttta
     4021 tattcatagt cccctccttt ccttttccct ctcatagacc ttgtttatat catcgagcag
     4081 cccggtcttt ccttttgcat cgaggaagga aacgatatgt tgcatggctt taagttgtgc
     4141 tgtttcattg gcttctatcc gcttgaaaat ggcctgctgg ttcttcctga tagttgcatc
     4201 agaatcccgt accgctcttt cagctctgtc aatggctttt cccttttcgc tggattgatt
     4261 catcacctcg atgaaaagtt cactgttctc cttcagaaac cgcctgaact tttcttccga
     4321 aagtaaggat gaaaggttta tggttatctg tgtgctggct ccggccagag cttcacaagc
     4381 cggacgcaca agatccgttt cctgtttctt caggaatgcg aatacctgat ccatgcgctt
     4441 gataagcttc tgcatttcct gtgccgggct ttcatgctcg accgggttta taccgtactt
     4501 ctcaaaatag tttatagcat gtgtaaggaa ctccattttt gacacattgt ttgccttggc
     4561 cagacggtca agtttagtaa aagtagtacg ttctactgct accgttgttt tactgtcttt
     4621 ttccatgata ttataagatt tattataatg aattaatata ctaatttact ggtttacaag
     4681 atagtatatt tattcattat aaccaaatta tattagtata attcactaaa tatctgattt
     4741 acagctaaaa accccgtagg acaagaggaa aaaacagggc ttgcccggtt tcctcttgct
     4801 gttctatcga acaccctccc cagcgcgaaa ttagcaaagg ggacggggag agatagaacc
     4861 tatcccacac acgtgaacac ccacgaaaac cgcacacctg gtacacaaca gaattaccca
     4921 acaaaaccgc acaacagaac gtgtccggaa caccacaaaa aactcatcgg tcggggagcg
     4981 ccgcacggca aggggcggga ccacccgtcc cgacgagtgc agccgtttac ttggacatat
     5041 gatataagtt attttgattc tgtcacaaaa tcaaaaggat tgcagtaagt tccaaaacgg
     5101 cacatactgc aatccttcat ttgtcgtcat aatgccccca ggctgaaatg atgaacacaa
     5161 ttacggtagt ctcgttgacc atatacctga tacggttctt cttgtccagc tgccttgacc
     5221 agacaccctc caggtatctc aactgttccg gatgccctgt acccgtatat gggtgttccc
     5281 ggagttcatc aagcagcttc tccagcttct tgaaaagctg cggagaggat tttctcatta
     5341 ataggacatg ttttaccgct tctttggaaa attctatctc atacattgcc ttcgccctct
     5401 atacggttaa gaaaatcgtc cagggactcg tttttagcca ttctgaaggt atttccgttt
     5461 ctgacatcat caatacccct ctggatggcc gcaagctctt cctttgaagg aaaatcgcct
     5521 tctctgaccg cacacaccat gataggggcc gcattgcgtc tggagatcag gatcgtttcc
     5581 gtctctgcca tttcgaagta tttcttctgg ttggcacgaa attcgcgtgt tgtaacaatc
     5641 tgcatagttc taatatgttg gtttacactg caaaaatagg gataaaaatc aataaagcaa
     5701 aagttttgtg tacttatttg tgtacacgcg cggaaagttc gttcctaaaa aaacgctgcg
     5761 ctggctcttg ctttgctttc acaaacattc aaaaactcgt ttttcacgga tttggaggtc
     5821 tggaagccac attcaggcta aaattttatg acttgttttt aagcattgct tattatatgc
     5881 ttatcaactt ttgaaaaatc atttataaaa tactgaataa caaatcatta caaagagtaa
     5941 aaacgctcga aaaacgactt tttgaatgtt ataaacgact tttttaatgt ttttttcgcc
     6001 tttaaaaacg actttttgaa tgtttacgac gacatacatt tttaaatgtc gtttttaatt
     6061 tctatatttg cgaacattca ttttgtcgtt ttttaaaaac aaaggagt
//
