LOCUS       NZ_CP070987            19830 bp    DNA     circular CON 23-MAY-2024
DEFINITION  Staphylococcus aureus strain WBG8287 plasmid pWBG750, complete
            sequence.
ACCESSION   NZ_CP070987
VERSION     NZ_CP070987.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14225426
            Assembly: GCF_017088305.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 19830)
  AUTHORS   Karakatsanis,N.M., Colombi,E., Mowlaboccus,S., Coombs,G.W. and
            Ramsay,J.P.
  TITLE     Genome sequence of early Western Australian community associated
            methicillin-resistant Staphylococcus aureus
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 19830)
  AUTHORS   Karakatsanis,N.M., Colombi,E., Mowlaboccus,S., Coombs,G.W. and
            Ramsay,J.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-FEB-2021) School of Pharmacy & Biomedical Sciences,
            Curtin University, Kent street, Bentley, WA 6102, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 22-FEB-2021
            Assembly Method :: Flye v. 2.8.3-b1695; guppy_basecaller v.
            4.4.1+1c81d62; racon v. 1.4.15; pilon v. 1.23
            Assembly Name                     :: WBG8287-ST1-nanopore-2021
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 306.0x
            Sequencing Technology :: Oxford Nanopore MinION; Illumina NextSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_017088305.1-RS_2024_05_23
            Annotation Date                   :: 05/23/2024 04:48:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,749
            CDSs (total)                      :: 2,669
            Genes (coding)                    :: 2,604
            CDSs (with protein)               :: 2,604
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 40 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 15 of 65
            Pseudo Genes (multiple problems)  :: 17 of 65
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP070987.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..19830
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="WBG8287"
                     /db_xref="taxon:1280"
                     /plasmid="pWBG750"
                     /geo_loc_name="Australia: Royal Perth Hospital, WA"
                     /collection_date="1995"
                     /identified_by="Frances O'Brien, School of Biomedical
                     Sciences, Curtin University of Technology, Perth, Western
                     Australia"
                     /note="ST1-MRSA-IVa (2B); clinical, community-acquired
                     infection"
     gene            1..861
                     /locus_tag="JYH18_RS13565"
                     /old_locus_tag="JYH18_13565"
     CDS             1..861
                     /locus_tag="JYH18_RS13565"
                     /old_locus_tag="JYH18_13565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000145511.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            complement(1329..2072)
                     /locus_tag="JYH18_RS13570"
                     /old_locus_tag="JYH18_13570"
     CDS             complement(1329..2072)
                     /locus_tag="JYH18_RS13570"
                     /old_locus_tag="JYH18_13570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843757.1"
                     /translation="MKSVKRLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESATEDKQKKESDNINFESKSDAQIVEILKNQINTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNAR
                     QNVDAQEKTYTTSPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAQREDVSANPND
                     NDSDIEEKSEETEAKKGFWSRLFGN"
                     /name="DUF536 domain-containing protein"
     gene            2483..3159
                     /locus_tag="JYH18_RS13575"
                     /old_locus_tag="JYH18_13575"
                     /pseudo=""
     CDS             2483..3159
                     /locus_tag="JYH18_RS13575"
                     /old_locus_tag="JYH18_13575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            <3170..3452
                     /locus_tag="JYH18_RS13780"
                     /pseudo=""
     CDS             <3170..3452
                     /locus_tag="JYH18_RS13780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            4661..5278
                     /gene="cadD"
                     /locus_tag="JYH18_RS13580"
                     /old_locus_tag="JYH18_13580"
     ARG             4662..5275
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="99.51"
                     /coverage="100.0"
     gene            5297..5644
                     /locus_tag="JYH18_RS13585"
                     /old_locus_tag="JYH18_13585"
     CDS             5297..5644
                     /locus_tag="JYH18_RS13585"
                     /old_locus_tag="JYH18_13585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119691.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNQEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            5813..5905
                     /locus_tag="JYH18_RS13590"
                     /old_locus_tag="JYH18_13590"
     CDS             5813..5905
                     /locus_tag="JYH18_RS13590"
                     /old_locus_tag="JYH18_13590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            6117..7091
                     /locus_tag="JYH18_RS13595"
                     /old_locus_tag="JYH18_13595"
     CDS             6117..7091
                     /locus_tag="JYH18_RS13595"
                     /old_locus_tag="JYH18_13595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="WP_000072388.1"
                     /translation="MSNTKIKYQIFISSTYLDLIEERQAVVEAVLNSNNIPAGMELFNS
                     SSKSQWEIITQWINESDAVILLLGSSYGTIDSEENISYTEMEYNFAKSLGKPIYVFEMN
                     KASTESAEKSKKLDEFKTKVKENRLISPNINDISELKSKVSQTLIQSVPSEIKENSGWI
                     RVQDCGKNVKKIKKLDAIQRDLDTYDFLKEELYKIFMYVKTFYFQHTPFDDSYIEDIEN
                     YLLNYENNPHKSFMKIKVYDYKNFLKHLKNILILIKQGKKPLAQAGHFKLSFYEEDLKL
                     LQKNYKATLVDIKGLNKHFYKECDRCLKAYNIFIEGINKHLYE"
                     /name="DUF4062 domain-containing protein"
     gene            complement(7211..8026)
                     /locus_tag="JYH18_RS13600"
                     /old_locus_tag="JYH18_13600"
     CDS             complement(7211..8026)
                     /locus_tag="JYH18_RS13600"
                     /old_locus_tag="JYH18_13600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000164957.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYNAPAEKQTKLRNDLYSITAIIDL
                     GQKLHVVNKYGHEHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKCQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            complement(8019..9462)
                     /locus_tag="JYH18_RS13605"
                     /old_locus_tag="JYH18_13605"
                     /pseudo=""
     CDS             complement(8019..9462)
                     /locus_tag="JYH18_RS13605"
                     /old_locus_tag="JYH18_13605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Mu transposase C-terminal domain-containing
                     protein"
                     /name="Mu transposase C-terminal domain-containing protein"
     gene            complement(9434..10027)
                     /locus_tag="JYH18_RS13610"
                     /old_locus_tag="JYH18_13610"
     CDS             complement(9434..10027)
                     /locus_tag="JYH18_RS13610"
                     /old_locus_tag="JYH18_13610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690638.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            complement(10291..10671)
                     /gene="blaI"
                     /locus_tag="JYH18_RS13615"
                     /old_locus_tag="JYH18_13615"
     ARG             complement(10295..10671)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            complement(10661..12418)
                     /gene="blaR1"
                     /locus_tag="JYH18_RS13620"
                     /old_locus_tag="JYH18_13620"
     ARG             complement(10665..12418)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.56"
                     /coverage="100.0"
     gene            12525..13370
                     /gene="blaZ"
                     /locus_tag="JYH18_RS13625"
                     /old_locus_tag="JYH18_13625"
     ARG             12526..13367
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            13739..14272
                     /locus_tag="JYH18_RS13630"
                     /old_locus_tag="JYH18_13630"
     CDS             13739..14272
                     /locus_tag="JYH18_RS13630"
                     /old_locus_tag="JYH18_13630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823239.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001823239.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGKSIENRPV
                     LQEALNFLRMGDRFVVESIDCLGRNYDEVVGNPLLDKFMKDLIIQILAMVSEQERNESK
                     RRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRIIYHRVVEMLEEGQSISKIAKEVNIT
                     RQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            14686..14979
                     /locus_tag="JYH18_RS13635"
                     /old_locus_tag="JYH18_13635"
     CDS             14686..14979
                     /locus_tag="JYH18_RS13635"
                     /old_locus_tag="JYH18_13635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WP_000726502.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            15054..16988
                     /locus_tag="JYH18_RS13640"
                     /old_locus_tag="JYH18_13640"
     CDS             15054..16988
                     /locus_tag="JYH18_RS13640"
                     /old_locus_tag="JYH18_13640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WP_000713729.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTAIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLILKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTLDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            16992..17303
                     /locus_tag="JYH18_RS13645"
                     /old_locus_tag="JYH18_13645"
     CDS             16992..17303
                     /locus_tag="JYH18_RS13645"
                     /old_locus_tag="JYH18_13645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WP_000831610.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            17315..17941
                     /locus_tag="JYH18_RS13650"
                     /old_locus_tag="JYH18_13650"
     CDS             17315..17941
                     /locus_tag="JYH18_RS13650"
                     /old_locus_tag="JYH18_13650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000593103.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            18179..18808
                     /gene="mobV"
                     /locus_tag="JYH18_RS13785"
                     /pseudo=""
     CDS             18179..18808
                     /gene="mobV"
                     /locus_tag="JYH18_RS13785"
                     /inference="COORDINATES: protein motif:HMM:NF013258.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            18902..19447
                     /locus_tag="JYH18_RS13665"
                     /old_locus_tag="JYH18_13665"
     CDS             18902..19447
                     /locus_tag="JYH18_RS13665"
                     /old_locus_tag="JYH18_13665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001805533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000273005.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTDFEKYTKQIKAAQMILD
                     DYECIKSGKSLKKAEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQEREIIFKEDREDGYTL"
                     /name="hypothetical protein"
     gene            complement(19489..19773)
                     /locus_tag="JYH18_RS13670"
     CDS             complement(19489..19773)
                     /locus_tag="JYH18_RS13670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001793642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001793642.1"
                     /translation="MKTFIHNKLLYYQCQTIKGVQLFKTLLLCGKNTPFMWQKHSFYVA
                     KTLLLCGKNTPLGIEIPCCSRAEQAPKKVFKKIYKNILKSSRGATYFSS"
                     /name="hypothetical protein"
     ARG             12526..13370
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     BGC             9686..19830
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          3510..3657
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.333"
                     /coverage="100.0"
                     /evalue="2.96e-25"
     Typing          2..861
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(1330..2072)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          18180..18454
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="94.565"
                     /coverage="100.0"
                     /evalue="4.71e-46"
ORIGIN
        1 atgacaggag agacagttgt atataaaaat gaaatgaatt tagttccatt aaggcgattt
       61 acagctactg aaattaattt attttttgcg atgtgtaata aattaaaaga gcaagatact
      121 aatacattac gtttgtcttt tgatgaatta aaaaaattaa gtaattatag tccagaaaca
      181 cgtaatatta atagatttgc taatgattta gataatgtgt ataaaaagat gttgaattta
      241 accattagat atgaagatga tgatgtaata gaaagattcg ttttattcaa tcattataga
      301 atccataagc gagaacaata tctagaaata tcaacttctt caaatttaaa acacatattg
      361 aattcaatta ctaataattt tacaaaattt gaattaaaag aaatgactag gcttaaatct
      421 acatattcta aaaatatgtt tagattactt aaacaataca aacatacagg ctatttaaaa
      481 attcacatcg atgattttaa aaatcgttta gatataccta aatcttatcg tatgactgat
      541 attaacaaaa atgtttttaa acctattatt attgaattag gttctatatt taataatctt
      601 actatcaata aaatcaaagc gaaaaaaggg cgtaaaattg aatggataga gttcacattt
      661 gacgctgaga aacgcattca taacaaacga caacctcaaa tgtccaagat agataaatca
      721 agacaatatg tgaggcgtga aaagacgcct aaatggttag aagaacggtc atatgaaaag
      781 caacctcaaa aagattacga cccacaatta gagaaagaac gagaggattt tttaaaacaa
      841 cttgaactga attgggaata acgcaacttt tcgttgcgag ttggttaact aaaagtatcg
      901 tgacttttca attattttaa ttatagtttg agttaaggag tgattttatg aaattagctg
      961 aagctataaa agaacagaga gaattaaaag gatggtctca agaggaggac atggtattat
     1021 ttcgaagtaa gaagtgtctg gcgtggcaaa catattatta gagttaaaga tggtttgtta
     1081 ggttggagaa aagaaatagt aactgaataa agatacaaaa tacttgccaa tgcaaaagaa
     1141 tgaaaacgcg tcaaatcaac gatgtataaa agatgcataa aagataatga aagtaaaaag
     1201 ccataaatgc cgtcatatag gcatttatgg ctttttgttt ggttaatata atcgatgatt
     1261 atcagaagtt caattcacat aaaaaagcac ggctaattta tgaacttgtc gtaccttttt
     1321 aattaaaatt agttaccaaa tagacgactc caaaacccct ttttagcttc cgtttcttca
     1381 ctcttttctt ctatatcact atcattgtca tttggattag ctgaaacgtc ttctctttgt
     1441 gcttcttcac cttgtgtact ttcgtcgctt tgacttccag atatatcctt atattgaatc
     1501 tctgtttctt tagtttcttc ctgatctcgg ttaatattta caggactagt agtatatgtt
     1561 ttttcttgtg catcaacgtt ttgtctagcg ttagtagatg tatcaaaggg ataattaagg
     1621 tgtttttctt tttctaattg attttctaat ttttgaatct ttttattact ctctaatgcc
     1681 agaacttgct gattctcaag caattttgat ctttcttgca actcttttct gtaaaattca
     1741 attgttgttt catgacgact ttcttgtttt tcaatttgat tatttaaagt attaatctga
     1801 tttttaagta tttctactat ttgagcatcg cttttagatt caaaattaat attatccgac
     1861 tctttttttt gtttgtcttc agtagcactt tcaaaaccat atttcttttt attttcattt
     1921 actctttgaa tgattttttc tatatcggta tcttctttaa taaacgaagt gttttcctgt
     1981 tttattgtct ctatattcaa tctcttaata ttattaaaaa tcgtttgctt actaacccct
     2041 aattcttcac tcaacctttt tacacttttc atatcatcaa ccctttataa aatgtttata
     2101 aacccttagt aaaatattat aagcttataa cgattaataa taaagtaatc gacaaataaa
     2161 aatataaatt cgccaacctt tttatcaagg gtttgtaaag ggtttatggt gtttatcaaa
     2221 ggtttataaa cctatatttt ccctttttta agtttattca aagtgctata ataaccttaa
     2281 tataacaaaa accccaacta ctggtaatag tcggggtttg gtaataaaac gtttagaaac
     2341 tgtttattta tataattttc gatacttaga ttatataatg aataatatct tagtgcaagc
     2401 acctagatta ttaaataaac acaaaaaatg taagcgtttt attacctctt accaaactaa
     2461 aattcggaaa gaggttttta ttatgtcaat taaactttac aacataaatg aggaatacag
     2521 agaaaagttt tatcaaatac cgaaagtatt ttttacaaat cctaaatata tcaagttatc
     2581 caatgatgca aaaatggcat ggggtattct tagagatcgt ttagatttat caattaaaaa
     2641 tggttgggtt gattctaaaa caggtaatat ttatttttat tacaaaaatg aaaacccaca
     2701 aaatatatta aattgtaaaa aagataaagt aattaaaata aagaaagaac ttaattgaag
     2761 ccgaattact actacaagaa agacaaggtt taaataagac aaataaactt tatttagtta
     2821 aaccagaagt aacagaagat gatatttata aaattcaaaa gcaagaaaac actgttgaga
     2881 gcagcaatgg caaggaagtc ggaaaaaccg acttcaagaa gtcgataaaa cagaatctaa
     2941 tgatactgaa cttagctata ctgaatctaa caatactgaa ataaatgata tgaatgactt
     3001 gaatgatata gagtccgaaa atgaaattag taatcattca agtcaatgca aggttattta
     3061 atgcaaacaa ttttaactga atttgaagaa acacatgcac tttatatgcg ccgtaaaaac
     3121 atgaaacaat ataatatctt taatcaatca ttcaaatgat tttataacaa tcaaagatac
     3181 atcaaaatat ttcgttaaat catctgactt tttaactgat agcgatgaaa aaatcaagaa
     3241 attgtcagtg atctagaaaa agatttgtat cgaaaacgta tgttaagtta tggtggattg
     3301 cttaaataaa aacataaaat tttaaactta gacgatgctg aagatggcaa tttaattaat
     3361 acaagtgatg aagataaaat agcaaatgaa gaagaaaagg cacattcgat tacggcaatt
     3421 ttgaaaagca aaattattat ttaaggcatt agtgataact gatgtctttt tttattactt
     3481 ttttgtaaaa aaagtgctgt cttatttttg tgacaaatgc tgtatgtagt gtcacaaaag
     3541 tgtgacactt gagcttttta tgaccccaca caaaaacatt ttcgaagcct tgaaatatct
     3601 ggctttgcca gatcccccat tcattgatgg ggacaaattt cccttatgct cttacggaga
     3661 ttttagagtt aaattaaaat ttctaagttt ttgataagaa aagccctgca ggaatttaga
     3721 agaacgtggg gaagttttaa agaattttat gctaattttt aatttgcatg taaatgggca
     3781 gtgtctaaaa aatagttatt gtttttgctc aaatttttgt ttttgaaaat agcatatatt
     3841 tatttggctc atatttgcgt tttaaaagcg tatataagtt ttagataaaa ctatatgaat
     3901 cacccctaaa tctttaaaat gccctcttaa aattcaaaat aagggcataa aaaataaaag
     3961 cccccccaga taaagtgagg tagctttttc tttcgacgcc gtatcgtcga tgtaattcaa
     4021 aaaagttatg ggctataaat ctacatcact ttttcaagaa tgtagtagca atattcaacg
     4081 caaattaatt tttataactg ctcggaatat ctcaagccgt ttctttaatt ttgaaataaa
     4141 aaaatcgacg aaggtcgatt acgtttttgc acatgtcgat ttatccgacg tataagtgcg
     4201 cccttacggg atttaactag attataacga cgaattttag acctgtaaag caataacaat
     4261 taggtctacc aggtagataa agtgtacaaa gtagaaccga aaaagttatt tattttgaag
     4321 atttttcgta gatataattt gctaataaac ttcctaaaac tgaataaaga aaaatagtta
     4381 aactcatgta atcactccat aattctgaag tgtctccatg tctacgcata gacacgcatt
     4441 tatgccgaga aaatttattg tgcgttgaga agaaccctta actaaacttg cagacgaatg
     4501 tcggcatagc gtgagctatt aagccgacca ttcgacaagt tttgggattg ttaagggttc
     4561 cgaggctcaa cgtcaataaa gcaattggaa taaagcacct atgattattt aaaaatataa
     4621 gttataatac attcaaaaat atttttgaat gaggtgtatt atgattcaaa cggttgttgc
     4681 tgctgctgtt ctttatattg ctacagcagt tgatttatta gtaattttat taatattttt
     4741 tgctagagca aagactagaa aagaatatag aaatatttat gttggtcaat atttagggtc
     4801 tattatttta atattagtta gtttgttttt agcttttgta ttaaattatg ttccagaaaa
     4861 gtggatatta ggtttattgg gtttaatacc aatttatctt ggaattaaag tggctattta
     4921 tgatgattgt gaaggagaaa agagagctaa aaaagaattg aatgaaaaag gattgtctaa
     4981 attagttggt acggttgcaa ttgttacgat agcaagttgt ggcgccgata atattggttt
     5041 atttgttcct tattttgtga cattaagtgt tactaattta ttacttactc tgtttgtctt
     5101 tttaatttta attttcttct tggtgtttac tgcacaaaaa ttagctaata tcccaggaat
     5161 tggagaaatt gttgagaaat ttagtcgttg gattatggct atcatttata tagctttagg
     5221 tttatttatt attattgaaa atgacactat tcaaacaatt ttaggattta tattttaatt
     5281 tagggtgtga ttttatatga gttatgaaaa tacttgtgat gtgatctgtg tacatgagga
     5341 taaagttaac aatgctttaa gttttttaga agatgataaa tctaagaaat tacttaacat
     5401 tttagaaaaa atttgtgatg agaagaaatt gaaaatcata ttatctttga ttaaagaaga
     5461 tgagttgtgt gtttgtgata tttctttgat attgaaaatg agtgttgctt caacttcaca
     5521 tcatttaagg cttttatata aaaatgaggt acttgatttt tataaagatg gaaagatggc
     5581 atattatttt attaaagacg atgaaataag agagtttttc tctaaaaatc aggagggttt
     5641 ttgaaacgag tgaaacgagt ttcttcttgt cttgatacta taaaaaacaa agttatataa
     5701 cataagacga cttatcggaa gttatctatc atcgtatatt cggagatgat ataatataca
     5761 ggtcgcctat ctctcaggcg tcaattcaga cgcagagagg aggtgcatta ctttgctaat
     5821 cattttcgtt cacatcatag caccagtcat cagtggctgt gctgttgcgt attatactta
     5881 ttggcttagt aaacgcaaca aataattaat aggcgacttt ataagccagc atcgaaaaaa
     5941 tccccacact attgcagtag tgtggggatt ggtgcattaa ttgttaatca ttttcgttat
     6001 ctagattata acactggtta gtagaggaat gcaaaaagat aatattttaa gtagtctttt
     6061 tggatattat catatgatat atttatgtaa attgattttt tattaaagga gcatatatga
     6121 gtaatactaa aattaaatat caaattttta tttcatcaac ttatttagat ttaatagaag
     6181 agcgtcaagc agtagtagaa gcagttttaa acagtaataa tattccagca ggtatggaac
     6241 tttttaactc aagtagtaaa agccaatggg aaataataac acaatggatc aatgaatcag
     6301 atgcagtgat attattgtta ggttctagtt atggaacaat tgatagtgaa gaaaatatta
     6361 gctatacaga aatggagtac aattttgcta aatctttagg taaacctata tatgtttttg
     6421 agatgaataa agcatctacc gaatccgcgg aaaagtctaa aaaattagat gagtttaaga
     6481 caaaagttaa agaaaataga ctaattagtc caaatattaa tgatatttcg gaattaaaaa
     6541 gtaaagtatc tcagacttta atacaaagtg tacctagtga aattaaagaa aatagtggat
     6601 ggataagagt acaggattgt ggtaaaaatg taaaaaaaat aaaaaaattg gatgctatac
     6661 aaagagattt agatacatat gattttttga aagaagaact ttataaaata ttcatgtatg
     6721 taaaaacttt ttatttccag cacacaccat ttgatgatag ttatattgaa gatatagaaa
     6781 actacctgct aaattatgaa aataatccac ataaatcatt catgaaaata aaagtttatg
     6841 attataaaaa ctttttaaaa catttaaaaa acatattgat tttaattaaa caaggaaaaa
     6901 agccattagc tcaagccggt cattttaaat taagctttta cgaagaggat ttaaaattgt
     6961 tacaaaaaaa ttataaggct acgctagtcg atattaaagg attgaataaa catttttata
     7021 aggaatgtga taggtgctta aaagcatata atatttttat tgagggtata aataaacatt
     7081 tatatgaatg atataagtac accctaatca tacatatata attgttgtca ctttactcga
     7141 tatatgagaa tgactttacc taataaatga gaaaagcaac gcactatatt aaaatgcgtt
     7201 gctttttcta ttatcgaata cctataacta aactatctct agctgtttct acaacttctg
     7261 tacttatttt atctaaacca tttatatcca taattctgtc tatctgcgca aataaacgat
     7321 gaatcagcct aaaattccct tttgtaattt taataatcgt cgttattgcc tcataatcag
     7381 taaagtcttc gagttttaaa tcaaatccta agtcttgaca cttatattct aatatatgat
     7441 gcgtctcatc tttacttaga ttatcaaatt catgcgcaaa acctatacgc gaatatagtt
     7501 gaggataacg agatagtttt ttctctatac ccggcatacc aataaatatc attgctaaat
     7561 tatgttcatc ataaatagct cttaattgct ctaaatgttg cactttaagg cgatcaatct
     7621 catctactat aattaaatca atatatttaa acatatcact ataatgttta ctatgttcat
     7681 gtccatactt atttacaaca tgtaattttt gacccaaatc aatgattgca gtaatactat
     7741 ataaatcatt ccttaattta gtttgttttt ctgctggtgc attataaaat attttatcca
     7801 ccgatagtat gtcatcggtc gttttactag ctaaatcttc ccaacctcta tggttaactt
     7861 gtttttcaat agtatcccaa tttgtgtaat acctagacga taaagttttt ccgacaccag
     7921 gttgaccata acatatacca atatactgat atttaataca agcatcacaa aattcagcaa
     7981 agcgtttata ctctttcgtt tcaatgaaat tttgattttt agtcattacg atatctcttt
     8041 aattttttga cgtttttagt cgtttcttga ggtgaataac cacaattttt ttcttcctta
     8101 attaattccg tggtacttgg actagcaata ttttgtttta agtgttttct tctctgacta
     8161 cgagcgtgct gtatgtcttt tatatctatg gagtaatcag ctatttctgg acatatagca
     8221 gtacaaagaa attcatctct ataaaacaca cgtatttcag ccatatcatt tgggttataa
     8281 cgaatcagta catattcacc tacataagct tctagattag tattactgta tcgaaaacct
     8341 tgaaaatgaa tgccatctga atgaactttt ctagatttag gtatttccaa caataataaa
     8401 tcaagttgtt ctaagctact tggcatatta gggaaaaagt gattactatt ccaatgactg
     8461 ataggcgtgg tatgaatagt actatgttct ttttgattat aatcttcaat taaaaagtaa
     8521 cgtaattttt cttcaaaatt gtgaaaattt attagattac taggagtatc attattgttt
     8581 atatatccag gcagttgttc taagaaagtt tgattaactg tctgaaagaa tcgttctatt
     8641 tttccacgac cacgaggaac accaactttc gaaaacatca agttaatttt caaatcaata
     8701 gcgacttgtt ccatatgatg tgaagtaaag tcacttccat gatctgtgta gaatttttcg
     8761 ggtataccac acactggcca attggtatca tttttattcc atattgcttg gtgtagtgtt
     8821 aatgctgtgt tttgagcatt ggggggcatc aaaacttaag aaatagcctg caattgcacg
     8881 actatagtca tccataataa tagttagcca tggtctattg atattacctt tttggtctaa
     8941 tataaagata tctagcaaag tatggtctgc ttgccatatt tcattgggtc tcgaggattc
     9001 tctaatttgt attaaatcgt acttattttg atagtatttt tcaccctgat gagagaaatc
     9061 aataacagac ttaggcatcg ctttaataac actataaatt tgtttataac ttggtatatc
     9121 aaaattattt tctttacagt aattagtgat tttcctatga attgtggcta tactatttct
     9181 tttattcata agcgcaaggc gttcaatttc atcaattatc tttggttcta ttttacgtgt
     9241 tcctttatca gctcttgtcg catagattag tcctttaagt ccttgttctt tatatgactt
     9301 attccaccta taaagggtgc ttaacgcaat ccctttactt ttagaaatac ttgataaaga
     9361 ttgttcgcct aggataaaag gttttataat attgtacttt tgagtagctt ttttacgttt
     9421 ggcttcagaa aaattagtta gatacttctc cttgtttttc atcttccttg tcctccaatt
     9481 tattgaggta acgataaatt gttgtacgtg aaacatgcca ctgttctgca attgtcttaa
     9541 ttggcgtgcc attatcataa agggtcttaa gtaagtttaa atctttttga tttaattttt
     9601 ctggtctgcc tccatatcgg cctctagcac gtgctgcaat tcggccagct gaagaacgct
     9661 ctaaaattaa attacgttca aattctgcaa atgctgcgaa taaatgaaat aataattgtc
     9721 cagttgaact tgatttatcc attgttatat tttcttctaa actatggaaa cttacacctc
     9781 gttcgttaag ctcattaact aatgtgatta aatcctccat attacgtccc aatctatcta
     9841 atctccaaac aacaatcgta tctcctgacc tcgcaaattc aattgcttta tctaaaccag
     9901 gtcttttact ttttgaacca ctcatatggt cattaaatat cttttcacaa ccatatgtat
     9961 ttaatcgatc ctcctgtaaa tttaaatttt gtaatccagt tgaaactctt gcataaccta
    10021 ttttcaaaat acaaacctcc tatatacatc ttcagtgtac cataacttaa ttacaaggtc
    10081 ttttatgaac atagattttt tgttgggttt ttgaacacat aatcctatgt aattcttact
    10141 tatttagaca taaaagaaga gtgtacagaa aatggttatt ttctgtacac tctcatcttt
    10201 aataatatat tttaaatgtc attaacaaaa ctaatttaat aagagtcaag catagtttac
    10261 atatgtatta tgtttgaaac atacctctaa ttacttttta ctaatatcat ttaaaatatc
    10321 tcgcaattct tcaatttctt tgttatttaa ttcttcattt ttcgcaaaat tcaacactaa
    10381 acttttcata tcccctccat acagtttatt aagaaaggtt ttagcagttt tcattttaat
    10441 atcgtcttct ttaatatttg atgagtaaaa ataaatattt tctgatttgt atcgttttat
    10501 aatctctttt ttatatagtc ttgtgattaa tgttctaatc gttttatcac taacttcttt
    10561 atatttttga atttcaacta caatttcatt agctgatact gattttttat cccatattat
    10621 attcataaca tcccattcag ccatagatat ttcaacttgc ttattggcca tttaaaacac
    10681 ccattccttt taatattttt tcacttatta attcagcatt tttcccagac gggtttccat
    10741 ctgataaatg tgtagcaaaa taatacttat catgatttgt aattacgtaa cctacaaacc
    10801 acccattatt atacttcccg tttactatac ctgtacctgt tttcccatac agttcatact
    10861 tttcattttt cttaatcaat aatgaagaag ataattgatt ctttgctttt ttactaaaat
    10921 ggttattttg ttccatcata tttttaaaaa ctattacttg ttcaagatta gatattttca
    10981 aactatcttc catccaatag cttttataac ttcccaaatt ttcattacca taatttaatt
    11041 gcttgagttg agccgcagta tagttctttg gtatttgatt actaatacgt tcgaagtacc
    11101 aattaactga attttgcatt gctgtattta aatcttgttc cttattccaa gactcgaaaa
    11161 gataatgttt atgattccat gacatacgtg aatttttatc acttataata tgacggtcaa
    11221 gtccaaacag tgctaaataa attttgtaag ttgaatcagg agaatatctt tttctacttt
    11281 ctttttcatt ataaatatag tatttgtctt tcttcatgct gtacataacg aaagatccac
    11341 tatttgaacc aaaattttta ctttcatcta aaatttggta atcgctttgt aagggctttt
    11401 tataattata atcagttaag gattgcccca ttaaaaactg gctttgaatt atcatgataa
    11461 aaaaagtaaa aatacaaata aaaattagaa ttaattttga ctgctttttc agatcggctt
    11521 cttttatatt aattaatcta tttttgagta atgatttttt accattaaat gaatggctta
    11581 atatattttt gttgaaaaat gaggttttta atacggagtc cataatagat tccgcataag
    11641 ttttaaattc atttttgtta atattattaa ggacaaatct atcggcttct acttcattgt
    11701 catgaattat ctttcttttt acaatatgta ctaatggatt gtaactcata ataatagaga
    11761 agatattaaa gataattaaa tgtaaagtat ctctattttt agcatgagca tattcatgca
    11821 gtattatata ttttagtctt ttatcaatta cacttttaaa atatgaacta ggaatcaaaa
    11881 taatatattt cccataccaa aaagttattg gagattgaat agcctctgct tttcgaatca
    11941 caatattttt tttatattga tggttgaaaa gtatcgtatc tattttattt ttttcatttt
    12001 cgtttagata aagtgactgt ttctttaaat atttaagata taataaggct ttcaaaaatt
    12061 taaaacttaa aataataact aaaactatcc aaataactgt gcagatatta tcaattgaat
    12121 cccaattaaa cttatggata tctgttgcga actcttgaac aggtttggtg gtaattatgt
    12181 tatggttcaa gtcgtgtgac ttactttcaa ctgtgggcgc ttgattattc acattattaa
    12241 attttataaa agagaattta attgggataa aaggaattaa tccagcaagc acagttagat
    12301 accaaacttt ataatttaaa ctataattaa aatagcgttt taatatgtac ctaaaaaaga
    12361 ctaacaatag aaatataaaa caaaagctta ctacactcat tattagtaat ttagccattt
    12421 tgacaccttc tttcaaatat ttataataaa caattgacat caatattaca attgtaatat
    12481 tattgttttg taaaaattac aactgtaata tcggagggtt tattttgaaa aagttaatat
    12541 ttttaattgt aatggcttta gttttaagtg catgtaattc aaacagttca catgccaaag
    12601 agttaaatga tttagaaaaa aaatataatg ctcatattgg tgtttatgct ttagatacta
    12661 aaagtggtaa ggaagtaaaa tttaattcag ataagagatt tgcctatgct tcgacttcaa
    12721 aagcgataaa tagtgctatt ttgttagaac aagtacctta taataagtta aataaaaaag
    12781 tacatattaa caaagatgat atagttgctt attctcctat tttagaaaaa tatgtaggaa
    12841 aagacatcac tttaaaagaa cttattgagg cttcaatgac atatagtgat aatacagcaa
    12901 acaataaaat tataaaagaa atcggtggaa tcaaaaaagt taaacaacgt ctaaaagaac
    12961 taggagataa agtaacaaat ccagttagat atgagataga attaaattac tattcgccaa
    13021 agagcaaaaa agatacttca acgcctgctg ctttcggcaa gactttaaat aaacttatcg
    13081 caaatggaaa attaagcaaa aaaaataaaa atttcttact tgatttaatg tttaataata
    13141 aaaacggaga cactttaatt aaagatggtg ttccaaaaga ctataaggtt gctgataaaa
    13201 gtggtcaagc aataacatat gcttctagaa atgatgttgc ttttgtttat cctaagggcc
    13261 aatctgaacc tattgtttta gtcattttta cgaataaaga caataaaagt gataagccaa
    13321 atgataagtt gataagtgaa accgccaaga gtgtaatgaa ggaattttaa tattctaaat
    13381 gcataataaa tactgataac atcttatagt ttgtattata ttttctatta tcgttgacat
    13441 gtataatttt gatatcaaaa cctgattttc cctttattat tttcgagatt tattttctta
    13501 attctcttta acaaactaga aatattgtat atacaaaaaa tcataaataa tagatgaata
    13561 gtttaattat aggtgttcat caatcgaaaa agcaacgtat cttatttaaa gtgcgttgct
    13621 tttttctcat ttataaggtt aaataattct catatatcaa gcaaagtgac ataattgttg
    13681 aatttatagt aactgaaacg tatgattagg gtgtatatta attatgagat ggaaatcaat
    13741 gattgttggc tatgcgagag tatcatcgaa cgatcaaaat ttagaaagac aacttgaaaa
    13801 tttaaagacg ttttgtgctg aaaaaatatt tacagaaaaa cagtctggga aatctattga
    13861 aaatagacca gtacttcaag aagcacttaa ctttttgagg atgggagatc ggtttgtagt
    13921 agaatccatt gattgtttag gtcgtaatta tgatgaagtg gttggcaatc cattactgga
    13981 taagtttatg aaagatttaa ttattcaaat attagcaatg gtttcagaac aagagagaaa
    14041 tgaaagtaaa cgtcgacaag cgcaaggaat tcaagttgcg aaggaaaaag gcgtatataa
    14101 agggcgcccc ttactttatt caccaaatgc taaagatcca cagaaacgta ttatttatca
    14161 tcgcgttgta gaaatgttag aagaaggcca atcaattagt aaaattgcga aagaagtaaa
    14221 tataacaagg cagacgattt acagaattaa aaacgataat gatttgattt aataaacttt
    14281 gtttcaatgc aactgagagc ttctcacagc gtctcaaaac agatgattat aatctattat
    14341 gagtttttaa taataagaca agaaaagaga gcgtaaatat gctctctctt tttctcatta
    14401 acgaacgttt ataacgcaat catgatgaga gtattaatac agttaattat ttgaaatact
    14461 ttagtttata taatgttgaa ttataggtag tgaaattgta tttattatac attgtcatat
    14521 cgttgtttaa tgatagttaa tttaaggata atagaattaa tattatatat agatgaacaa
    14581 aacaagcaac agagcagaaa aaacactttt agattatttt tactcattct ctattttatt
    14641 tatttttgct ataataaata aataatatta aatggaggtg tttttatgaa aaagaaattt
    14701 gtttctagtt gtattgctag tacaatctta ttcggcactt tattaggtgt aacttataaa
    14761 gctgaagctg caacagtaca tgtagctggt ggtgtttgga gccatggtat tggaaaacat
    14821 tacgtatggt cttattatag tcacaataaa agaaatcatg gttcaacagc agtagggaaa
    14881 tattcatctt ttagtggtgt tgctcgacct ggtgttcaat ctaaggcatc tgctccaaag
    14941 gcttggggtg gaaacaaaac attttatagt cttcactaat tacatatatt aattaaggag
    15001 aatagacaga attaagtaaa cttaattctg tctattctct tgaaagaggc aatatgaaaa
    15061 aattcaaatt atttttagat tttagtactt tattattaat ttcagggcta ttatttttat
    15121 ttttcttcaa agaaaatgaa gaaattatac ctgaaagttc caatatttta acaatctcta
    15181 attgggataa atctaacagt aaatcaaaag tgttagatgt cattgaatca ggcgccaaaa
    15241 atcaaaatat acaaataatt aaatccgtta aagattttga taataaaaaa gaattttttg
    15301 ttttcaactc aaaacgaaat aattctgact ttatacgtaa taaaacatca cttttaactc
    15361 catcagattt attaaacaga gagataaaag gaaagtatta tattattggt gaacatttca
    15421 atgtagaaga gcttacgagt gaattaaaaa aagctggttt aacatctgaa gttgaataca
    15481 taaatagaaa catattattt tttgaattag tcatagataa tgatttatta gtgcctttca
    15541 tattcttagg cgtattatat cttttgtact tcttatatga cagaggatat aatttgaaat
    15601 tttatgctat tcaaaagcta catggctttt caactacacg cattattttt cataatattc
    15661 atataaaaat catttattgg ctagtactta ccgctatttt ctttattgct aatatattaa
    15721 tcattcatat agccaattta gaattggatt tcttaatgtt tattcgtaga tttatcgtgt
    15781 tgctttttgt ttttgcttgt attactacat tgctgtggct gatttcgtat agtcttcttt
    15841 tgaagttaag tattccatta atcttaaaag ggaaaaaagg atataagttt tcaatattta
    15901 tgggtacctt caccaaatgt atcatggtgc taatactatc ttttttactg gcacaaaatt
    15961 taaatgctta tacgaagtta aagaatatat atgactctga aaaaatctgg caaaagttag
    16021 ataattacta tacattagag atttctccta atattagaaa ttcagaagaa aaacaaattt
    16081 tagaaactaa tatatacaat ttaattaaga aaagcgaaca acttggtgga ttgcttttaa
    16141 agaataataa tatagccaat cccgataaaa acaattacat tcctgaaaat ggcaatgtct
    16201 tttttatcaa taacaatttt ctgaatttct ataaaaatat aaatcatgat tttaaaatga
    16261 ttgacaatca ttcggataaa ataaacgtgt ttattcctcc aaggttacaa tatcaaaaat
    16321 ctgaaattca aaaaaatcac caaggatgga ttgactttca aaagcaacaa aacaaaaaag
    16381 tagatgtgca agtactgtca aaaaacgtat ctgttttttc ttttgatcgc acaactaatt
    16441 tgaaatttgg gtatctagat tctccaatag taatgttgtt gacacttgac gatttaacag
    16501 gagattttta tttagctgct gtttctcaag gtggatatct atttaaagat ttagatacac
    16561 ttaaacagtt gcttaaagat aatcacctag aagaagaaat tagcggtata actaattaca
    16621 aggattctgt gttaaatgaa ttaaatgaaa cgaaaacaaa aatgataata acaatagtta
    16681 ctattattat taacgttttc attcttttga tagctactgt atttgaaaca attcaatatt
    16741 ttagctggaa taaaaagcaa ctattattaa gaaaaattca tggttattca ttattcagca
    16801 gtaatgtacg ttatttaaca atttctatct tactttctat tatgttagct tacactacgc
    16861 atattttatt tggttcaaag atattactat tcataataat gtctattgct attattcaac
    16921 atttacttca aattgcttat attaaatatc ttgaaaaata ctttaaagat ttaatgaggg
    16981 agatttaaac aatgaaaaga actttaatta ttgtaacaat tgtactatta atcatcatac
    17041 ttagtctgtt attggttaga aatgagcatt tagatcgttt taacccactg ttaaaagaaa
    17101 aagtatctta tgccaaagtt ccaaaagata cccaggacta tagaaatata actgtatact
    17161 ctaaaaatgg agaaaaaaag agttataaat tggatttttt aggttatgat cctacaaaag
    17221 aatatgtgaa agtaaatcat aaagggaaat atgtgcgttc gatagaatac attacaaaag
    17281 atattcctag ctttttaaaa tgaggtgacc gatagtgata aaacttgaaa atgtttttgt
    17341 aaaaaaaggt aataaaaaca ttttagacgg atgtaacttt aattttgaaa aaggaaaatc
    17401 atatgcttta gttggagaaa gtggcgctgg aaaatctact ttacttaaca taatcgctgg
    17461 gttcgaagat gtatcacaag gaagcatata tattgaagat aagttactaa aaaagaaagt
    17521 cgatttttat agatatacgt tagggtattt gtttcaaaat tttgctttac ttgaaaatca
    17581 aacaatcagt caaaatttag atttagccct aaagttcaaa aagaataaaa aagataatat
    17641 gaacttaaag aaagaagtat taaaaaaggt cggcctagat ttagatatca agagaattgt
    17701 tagttctcta agcggtggtg aacaacaaag agtagcattg gcaagattaa tattaaaaga
    17761 tccgaaaatc attttagctg atgaacctac tgggtcacta gatacgaaaa atggaaaaat
    17821 agttattgat ttattattga agctacttga tgaaaataaa actatgattg tcgtaacgca
    17881 tgatttagag cttgcgaaac gatttgatgt catagtcaat atttctgagc ttagaagtta
    17941 agaaatattg ataggtatag ccatacatag agaaaaaaca atatgaaata tgattagtca
    18001 ttacttttga gttttttaat ttaaggactg gattttccag tcctttttta tgatgataaa
    18061 aaacaagcct cgcagagcac acgtttttaa tgacttattt ggtttttaat aagtctagta
    18121 tgttaaaact tttctgtgtt taggtgttat aatcatatgc agtggaagtt gatttattat
    18181 gtcttattca attattcgag ttgttaaagt gaaatcaaaa acaaatacaa gaggtattca
    18241 aagacatatt caaagagaaa ataaaaatta tgaaaatata gatattgatt taagtaagtc
    18301 atatttaaac tatgatttag tcaatgatac taagtttgat tttaataaaa aaattgatga
    18361 gaaaatcgaa aaaaattata aagggaaacg caaaattaga acagatgcca ttaaacatat
    18421 tgatggatta attacatcag ataatgtgtt ttttaatcaa ttatctgaag aagagacaaa
    18481 atagtttttt aagcatgcta aagcgttctt ggaagaagaa tacggtaaag aaaatctttt
    18541 atatgcgaca gtacatatgg atgagataac accacatatg cattatggcg tagttcctat
    18601 tactaaagat ggacgtttaa gtgcgaaaga agttgtaggt aataaaaaag cattaaccga
    18661 attccaagat agattcaata cgtatattaa taagcaaggc tatgatttaa aacgaggaat
    18721 ttctagacaa cttacaaaag aaaaacatga tcaagttagc cgttataaac aaaaaacaga
    18781 atatcataaa caaatgcata tgcgctagaa gcaaatagag gattatttaa agcaagaaaa
    18841 tgataaattg atacaaaact accaaaaatc attagatacg cttaaaaagc ttctgagtgt
    18901 catgtatgaa attaaaacta aaaatgtagg tggatggttt cataaagaga agcaagaaac
    18961 aggcaatatt gtaattacta aaactgattt tgaaaaatac actaaacaaa ttaaagcagc
    19021 acagatgata ttagatgatt atgaatgtat taaaagtggg aagtcattaa aaaaagcaga
    19081 gaaacaaaat gaaagtttag ttaatgaatt gactagtgtc catatggaaa atgaaaagct
    19141 ggttgaagaa tttaatgatt tagcacaacg ttataattat ttgttgtcag agaatgaaaa
    19201 gaaagataaa gaactaaatt atacgcttaa gttattcaat caagttttta aaatcattaa
    19261 aagtatgatg aaagaagagc gttatcatac actaataaat catattgata atcatttaga
    19321 caattctaaa atacgtgaag taatgacgat agataacaat gatgaacagt tctttaagaa
    19381 gaaatatcaa gcacaagaac gagaaatcat ttttaaagaa gatagagaag atggttatac
    19441 attataaaaa tagatattta aatgcatttg tttgaggtta attatttttt aggatgaaaa
    19501 ataggtagcc cccctcgaac tttttaatat atttttataa atctttttaa aaaccttttt
    19561 aggggcttgt tcagccctag agcaacaagg gatttcaatg cctaaaggag tgtttttgcc
    19621 acataaaagg agtgtttttg ccacataaaa ggagtgtttt tgccacataa aaggagtgtt
    19681 tttgccacat aaaaggagtg ttttaaaaag ttgtactcct tttatggttt gacattgata
    19741 ataaagtagt ttattgtgaa taaaagtttt caaatgggag tgtatattca aacgatactc
    19801 ctttaggttc gtaataaagg gggctgtatc
//
