LOCUS       NZ_CP070984            20730 bp    DNA     circular CON 23-MAY-2024
DEFINITION  Staphylococcus aureus strain WBG8366 plasmid pWBG763, complete
            sequence.
ACCESSION   NZ_CP070984
VERSION     NZ_CP070984.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14225473
            Assembly: GCF_017088385.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 20730)
  AUTHORS   Karakatsanis,N.M., Colombi,E., Mowlaboccus,S., Coombs,G.W. and
            Ramsay,J.P.
  TITLE     Genome sequence of early Western Australian community associated
            methicillin-resistant Staphylococcus aureus
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 20730)
  AUTHORS   Karakatsanis,N.M., Colombi,E., Mowlaboccus,S., Coombs,G.W. and
            Ramsay,J.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-FEB-2021) School of Pharmacy & Biomedical Sciences,
            Curtin University, Kent street, Bentley, WA 6102, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 22-FEB-2021
            Assembly Method :: Flye v. 2.8.3-b1695; guppy_basecaller v.
            4.4.1+1c81d62; racon v. 1.4.15; pilon v. 1.23
            Assembly Name                     :: WBG8366-ST78-nanopore-2021
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 152.0x
            Sequencing Technology :: Oxford Nanopore MinION; Illumina NextSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_017088385.1-RS_2024_05_23
            Annotation Date                   :: 05/23/2024 04:37:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,790
            CDSs (total)                      :: 2,708
            Genes (coding)                    :: 2,635
            CDSs (with protein)               :: 2,635
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 35 of 73
            Pseudo Genes (incomplete)         :: 37 of 73
            Pseudo Genes (internal stop)      :: 16 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP070984.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..20730
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="WBG8366"
                     /db_xref="taxon:1280"
                     /plasmid="pWBG763"
                     /geo_loc_name="Australia: remote Western Australia"
                     /collection_date="1995"
                     /identified_by="Frances O'Brien, School of Biomedical
                     Sciences, Curtin University of Technology, Perth, Western
                     Australia"
                     /note="ST78-MRSA-IVa (2B); screening"
     gene            1..677
                     /locus_tag="JX573_RS13740"
                     /old_locus_tag="JX573_13735"
                     /pseudo=""
     CDS             1..677
                     /locus_tag="JX573_RS13740"
                     /old_locus_tag="JX573_13735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            <688..970
                     /locus_tag="JX573_RS14010"
                     /pseudo=""
     CDS             <688..970
                     /locus_tag="JX573_RS14010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            2181..2798
                     /gene="cadD"
                     /locus_tag="JX573_RS13745"
                     /old_locus_tag="JX573_13740"
     ARG             2182..2795
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="99.51"
                     /coverage="100.0"
     gene            2817..3164
                     /locus_tag="JX573_RS13750"
                     /old_locus_tag="JX573_13745"
     CDS             2817..3164
                     /locus_tag="JX573_RS13750"
                     /old_locus_tag="JX573_13745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119691.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNQEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            3333..3425
                     /locus_tag="JX573_RS13755"
                     /old_locus_tag="JX573_13750"
     CDS             3333..3425
                     /locus_tag="JX573_RS13755"
                     /old_locus_tag="JX573_13750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            3637..4611
                     /locus_tag="JX573_RS13760"
                     /old_locus_tag="JX573_13755"
     CDS             3637..4611
                     /locus_tag="JX573_RS13760"
                     /old_locus_tag="JX573_13755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="WP_000072391.1"
                     /translation="MSNTKIKYQIFISSTYLDLIEERQAVVEAVLNSNNIPAGMELFNS
                     SSKSQWEIITQWINESDAVILLLGSSYGTIDSEENISYTEMEYNFAKSLGKPIYVFEMN
                     KASTESAEKSKKLDEFKTKVKENRLISPNINDISELKSKVSQTLMQSVPSEIKENSGWI
                     RVQDCGKNVKKLKKLDAIQRDLDTYDFLKEELYKIFMYVKTFYFQHTPFDDSYIEDIEN
                     YLLNYENNPHKSFMKIKVYDYKNFLKHLKNILILIKQGKKPLAQAGHFKLSFYEEDLKL
                     LQKNYKTTLVDIKGLNKHFYKECDRCLKAYNIFIEGINKHLYE"
                     /name="DUF4062 domain-containing protein"
     gene            complement(4731..5546)
                     /locus_tag="JX573_RS13765"
                     /old_locus_tag="JX573_13760"
     CDS             complement(4731..5546)
                     /locus_tag="JX573_RS13765"
                     /old_locus_tag="JX573_13760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000164958.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYNAPAEKQTKLRNDLYSITAIIDL
                     GQKLHVVNKYGHEHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            complement(5539..6982)
                     /locus_tag="JX573_RS13770"
                     /old_locus_tag="JX573_13765"
                     /pseudo=""
     CDS             complement(5539..6982)
                     /locus_tag="JX573_RS13770"
                     /old_locus_tag="JX573_13765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Mu transposase C-terminal domain-containing
                     protein"
                     /name="Mu transposase C-terminal domain-containing protein"
     gene            complement(6954..7547)
                     /locus_tag="JX573_RS13775"
                     /old_locus_tag="JX573_13770"
     CDS             complement(6954..7547)
                     /locus_tag="JX573_RS13775"
                     /old_locus_tag="JX573_13770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690638.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            complement(7811..8191)
                     /gene="blaI"
                     /locus_tag="JX573_RS13780"
                     /old_locus_tag="JX573_13775"
     ARG             complement(7815..8191)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            complement(8181..9938)
                     /gene="blaR1"
                     /locus_tag="JX573_RS13785"
                     /old_locus_tag="JX573_13780"
     ARG             complement(8185..9938)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.56"
                     /coverage="100.0"
     gene            10045..10890
                     /gene="blaZ"
                     /locus_tag="JX573_RS13790"
                     /old_locus_tag="JX573_13785"
     ARG             10046..10887
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            11259..11867
                     /locus_tag="JX573_RS13795"
                     /old_locus_tag="JX573_13790"
     CDS             11259..11867
                     /locus_tag="JX573_RS13795"
                     /old_locus_tag="JX573_13790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002436987.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001566953.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGKSIENRPV
                     LQEALNFLRMGDRFVVESIDCLGRNYDEVIHTVNYLKDKEVQLMITSLPMMNEVVGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGQSISKIAKEVNITRQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            12281..12574
                     /locus_tag="JX573_RS13800"
                     /old_locus_tag="JX573_13795"
     CDS             12281..12574
                     /locus_tag="JX573_RS13800"
                     /old_locus_tag="JX573_13795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WP_000726502.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            12649..14583
                     /locus_tag="JX573_RS13805"
                     /old_locus_tag="JX573_13800"
     CDS             12649..14583
                     /locus_tag="JX573_RS13805"
                     /old_locus_tag="JX573_13800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WP_000713729.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTAIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLILKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTLDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            14587..14898
                     /locus_tag="JX573_RS13810"
                     /old_locus_tag="JX573_13805"
     CDS             14587..14898
                     /locus_tag="JX573_RS13810"
                     /old_locus_tag="JX573_13805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WP_000831610.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            14910..15536
                     /locus_tag="JX573_RS13815"
                     /old_locus_tag="JX573_13810"
     CDS             14910..15536
                     /locus_tag="JX573_RS13815"
                     /old_locus_tag="JX573_13810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000593103.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            15774..16403
                     /gene="mobV"
                     /locus_tag="JX573_RS14015"
                     /pseudo=""
     CDS             15774..16403
                     /gene="mobV"
                     /locus_tag="JX573_RS14015"
                     /inference="COORDINATES: protein motif:HMM:NF013258.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            16497..17042
                     /locus_tag="JX573_RS13830"
                     /old_locus_tag="JX573_13825"
     CDS             16497..17042
                     /locus_tag="JX573_RS13830"
                     /old_locus_tag="JX573_13825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001805533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000273005.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTDFEKYTKQIKAAQMILD
                     DYECIKSGKSLKKAEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQEREIIFKEDREDGYTL"
                     /name="hypothetical protein"
     gene            complement(17084..17368)
                     /locus_tag="JX573_RS13835"
     CDS             complement(17084..17368)
                     /locus_tag="JX573_RS13835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001793642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001793642.1"
                     /translation="MKTFIHNKLLYYQCQTIKGVQLFKTLLLCGKNTPFMWQKHSFYVA
                     KTLLLCGKNTPLGIEIPCCSRAEQAPKKVFKKIYKNILKSSRGATYFSS"
                     /name="hypothetical protein"
     gene            17426..18286
                     /locus_tag="JX573_RS13840"
                     /old_locus_tag="JX573_13830"
     CDS             17426..18286
                     /locus_tag="JX573_RS13840"
                     /old_locus_tag="JX573_13830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000145511.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            18373..18714
                     /locus_tag="JX573_RS13845"
                     /old_locus_tag="JX573_13835"
     CDS             18373..18714
                     /locus_tag="JX573_RS13845"
                     /old_locus_tag="JX573_13835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000761341.1"
                     /translation="MKLAEAIKEQRELKGWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRVPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(18953..19024)
                     /locus_tag="JX573_RS13850"
                     /old_locus_tag="JX573_13840"
     CDS             complement(18953..19024)
                     /locus_tag="JX573_RS13850"
                     /old_locus_tag="JX573_13840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_106873653.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGY"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            19173..19358
                     /locus_tag="JX573_RS13855"
                     /old_locus_tag="JX573_13845"
     CDS             19173..19358
                     /locus_tag="JX573_RS13855"
                     /old_locus_tag="JX573_13845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466619.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSVWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            complement(19577..20320)
                     /locus_tag="JX573_RS13860"
                     /old_locus_tag="JX573_13850"
     CDS             complement(19577..20320)
                     /locus_tag="JX573_RS13860"
                     /old_locus_tag="JX573_13850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843758.1"
                     /translation="MKSVKRLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESATEDKQKKESDNINFESKSDAQIVEILKNQINTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNAR
                     QNVDAQEKTYTTSPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAQREDVSANPND
                     NDSDIEEKSEETEPKKGFWSRLFGN"
                     /name="DUF536 domain-containing protein"
     ARG             10046..10890
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     BGC             7281..17574
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          1028..1175
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.333"
                     /coverage="100.0"
                     /evalue="2.96e-25"
     Typing          17427..18286
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(19578..20320)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          15775..16049
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="94.565"
                     /coverage="100.0"
                     /evalue="4.71e-46"
ORIGIN
        1 atgtcaatta aactttacaa cataaatgag gaatacagag aaaagtttta tcaaataccg
       61 aaagtatttt ttacaaatcc taaatatatc aagttatcca atgatgcaaa aatggcatgg
      121 ggtattctta gagatcgttt agatttatca attaaaaatg gttgggttga ttctaaaaca
      181 ggtaatattt atttttatta caaaaatgaa aacccacaaa atatattaaa ttgtaaaaaa
      241 gataaagtaa ttaaaataaa gaaagaactt aattgaagcc gaattactac tacaagaaag
      301 acaaggttta aataagacaa ataaacttta tttagttaaa ccagaagtaa cagaagatga
      361 tatttataaa attcaaaagc aagaaaacac tgttgagagc agcaatggca aggaagtcgg
      421 aaaaaccgac ttcaagaagt cgataaaaca gaatctaatg atactgaact tagctatact
      481 gaatctaaca atactgaaat aaatgatatg aatgacttga atgatataga gtccgaaaat
      541 gaaattagta atcattcaag tcaatgcaag gttatttaat gcaaacaatt ttaactgaat
      601 ttgaagaaac acatgcactt tatatgcgcc gtaaaaacat gaaacaatat aatatcttta
      661 atcaatcatt caaatgattt tataacaatc aaagatacat caaaatattt cgttaaatca
      721 tctgactttt taactgatag cgatgaaaaa atcaagaaat tgtcagtgat ctagaaaaag
      781 atttgtatcg aaaacgtatg ttaagttatg gtggattgct taaataaaaa cataaaattt
      841 taaacttaga cgatgctgaa gatggcaatt taattaatac aagtgatgaa gataaaatag
      901 caaatgaaga agaaaaggca cattcgatta cggcaatttt gaaaagcaaa attattattt
      961 aaggcattag tgataactga tgtctttttt tattactttt ttgtaaaaaa agtgctgtct
     1021 tatttttgtg acaaatgctg tatgtagtgt cacaaaagtg tgacacttga gctttttatg
     1081 accccacaca aaaacatttt cgaagccttg aaatatctgg ctttgccaga tcccccattc
     1141 attgatgggg acaaatttcc cttatgctct tacggagatt ttagagttaa attaaaattt
     1201 ctaagttttt gataagaaaa gccctgcagg aatttagaag aacgtgggga agttttaaag
     1261 aattttatgc taatttttaa tttgcatgta aatgggcagt gtctaaaaaa tagttattgt
     1321 ttttgctcaa atttttgttt ttgaaaatag catatattta tttggctcat atttgcgttt
     1381 taaaagcgta tataagtttt agatataaaa ctatatgaat cacccctaaa tctttaaaat
     1441 gccctcttaa aattcaaaat aagggcataa aaaataaaag cccccccaga taaagtgagg
     1501 tagctttttc tttcgacgcc gtatcgtcga tgtaattcaa aaaagttatg ggctataaat
     1561 ctacatcact ttttcaagaa tgtagtagca atattcaacg caaattaatt tttataactg
     1621 ctcggaatat ctcaagccgt ttctttaatt ttgaaataaa aaaatcgacg aaggtcgatt
     1681 acgtttttgc acatgtcgat ttatccgacg tataagtgcg cccttacggg atttaactag
     1741 attataacga cgaattttag acctgtaaag caataacaat taggtctacc aggtagataa
     1801 agtgtacaaa gtagaaccga aaaagttatt tattttgaag atttttcgta gatataattt
     1861 gctaataaac ttcctaaaac tgaataaaga aaaatagtta aactcatgta atcactccat
     1921 aattctgaag tgtctccatg tctacgcata gacacgcatt tatgccgaga aaatttattg
     1981 tgcgttgaga agaaccctta actaaacttg cagacgaatg tcggcatagc gtgagctatt
     2041 aagccgacca ttcgacaagt tttgggattg ttaagggttc cgaggctcaa cgtcaataaa
     2101 gcaattggaa taaagcacct atgattattt aaaaatataa gttataatac attcaaaaat
     2161 atttttgaat gaggtgtatt atgattcaaa cggttgttgc tgctgctgtt ctttatattg
     2221 ctacagcagt tgatttatta gtaattttat taatattttt tgctagagca aagactagaa
     2281 aagaatatag aaatatttat gttggtcaat atttagggtc tattatttta atattagtta
     2341 gtttgttttt agcttttgta ttaaattatg ttccagaaaa gtggatatta ggtttattgg
     2401 gtttaatacc aatttatctt ggaattaaag tggctattta tgatgattgt gaaggagaaa
     2461 agagagctaa aaaagaattg aatgaaaaag gattgtctaa attagttggt acggttgcaa
     2521 ttgttacgat agcaagttgt ggcgccgata atattggttt atttgttccg tattttgtga
     2581 cattaagtgt tactaattta ttacttactc tgtttgtctt tttaatttta attttcttct
     2641 tggtgtttac tgcacaaaaa ttagctaata tcccaggaat tggagaaatt gttgagaaat
     2701 ttagtcgttg gattatggct atcatttata tagctttagg tttatttatt attattgaaa
     2761 atgacactat tcaaacaatt ttaggattta tattttaatt tagggtgtga ttttatatga
     2821 gttatgaaaa tacttgtgat gtgatctgtg tacatgagga taaagttaac aatgctttaa
     2881 gttttttaga agatgataaa tctaagaaat tacttaacat tttagaaaaa atttgtgatg
     2941 agaagaaatt gaaaatcata ttatctttga ttaaagaaga tgagttgtgt gtttgtgata
     3001 tttctttgat attgaaaatg agtgttgctt caacttcaca tcatttaagg cttttatata
     3061 aaaatgaggt acttgatttt tataaagatg gaaagatggc atattatttt attaaagacg
     3121 atgaaataag agagtttttc tctaaaaatc aggagggttt ttgaaacgag tgaaacgagt
     3181 ttcttcttgt cttgatacta taaaaaacaa agttatataa cataagacga cttatcggaa
     3241 gttatctatc atcgtatatt cggagatgat ataatataca ggtcgcctat ctctcaggcg
     3301 tcaattcaga cgcagagagg aggtgcatta ctttgctaat cattttcgtt cacatcatag
     3361 caccagtcat cagtggctgt gctgttgcgt attatactta ttggcttagt aaacgcaaca
     3421 aataattaat aggcgacttt ataagccagc atcgaaaaaa tccccacact attgcagtag
     3481 tgtggggatt ggtgcattaa ttgttaatca ttttcgttat ctagattata acactggtta
     3541 gtagaggaat gcaaaaagat aatattttaa gtagtctttt tggatattat catatgatat
     3601 atttatgtaa attgattttt tattaaagga gcatatatga gtaatactaa aattaaatat
     3661 caaattttta tttcatcaac ttatttagat ttaatagaag agcgtcaagc agtagtagaa
     3721 gcagttttaa acagtaataa tattccagca ggtatggaac tttttaactc aagtagtaaa
     3781 agccaatggg aaataataac acaatggatc aatgaatcag atgcagtgat attattgtta
     3841 ggttctagtt atggaacaat tgatagtgaa gaaaatatta gctatacaga aatggagtac
     3901 aattttgcta aatctttagg taaacctata tatgtttttg agatgaataa agcatctacc
     3961 gaatccgcgg aaaagtctaa aaaattagat gagtttaaga caaaagttaa agaaaataga
     4021 ctaattagtc caaatattaa tgatatttcg gaattaaaaa gtaaagtatc tcagacttta
     4081 atgcaaagtg tacctagtga aattaaagaa aatagtggat ggataagagt acaggattgt
     4141 ggtaaaaatg taaaaaaatt aaaaaaattg gatgctatac aaagagattt agatacatat
     4201 gattttttga aagaagaact ttataaaata ttcatgtatg taaaaacttt ttatttccag
     4261 cacacaccat ttgatgatag ttatattgaa gatatagaaa actacctgct aaattatgaa
     4321 aataatccac ataaatcatt catgaaaata aaagtttatg attataaaaa ctttttaaaa
     4381 catttaaaaa acatattgat tttaattaaa caaggaaaaa agccattagc tcaagccggt
     4441 cattttaaat taagctttta cgaagaggat ttaaaattgt tacaaaaaaa ttataagact
     4501 acgctagtcg atattaaagg attgaataaa catttttata aggaatgtga taggtgctta
     4561 aaagcatata atatttttat tgagggtata aataaacatt tatatgaatg atataagtac
     4621 accctaatca tacatatata attgttgtca ctttactcga tatatgagaa tgactttacc
     4681 taataaatga gaaaagcaac gcactatatt aaaatgcgtt gctttttcta ttatcgaata
     4741 cctataacta aactatctct agctgtttct acaacttctg tacttatttt atctaaacca
     4801 tttatatcca taattctgtc tatctgcgca aataaacgat gaatcagcct aaaattccct
     4861 tttgtaattt taataatcgt cgttattgcc tcataatcag taaagtcttc gagttttaaa
     4921 tcaaatccta agtcttgcca cttatattct aatatatgat gcgtctcatc tttacttaga
     4981 ttatcaaatt catgcgcaaa acctatacgc gaatatagtt gaggataacg agatagtttt
     5041 ttctctatac ccggcatacc aataaatatc attgctaaat tatgttcatc ataaatagct
     5101 cttaattgct ctaaatgttg cactttaagg cgatcaatct catctactat aattaaatca
     5161 atatatttaa acatatcact ataatgttta ctatgttcat gtccatactt atttacaaca
     5221 tgtaattttt gacccaaatc aatgattgca gtaatactat ataaatcatt ccttaattta
     5281 gtttgttttt ctgctggtgc attataaaat attttatcca ccgatagtat gtcatcggtc
     5341 gttttactag ctaaatcttc ccaacctcta tggttaactt gtttttcaat agtatcccaa
     5401 tttgtgtaat acctagacga taaagttttt ccgacaccag gttgaccata acatatacca
     5461 atatactgat atttaataca agcatcacaa aattcagcaa agcgtttata ctctttcgtt
     5521 tcaatgaaat tttgattttt agtcattacg atatctcttt aattttttga cgtttttagt
     5581 cgtttcttga ggtgaataac cacaattttt ttcttcctta attaattccg tggtacttgg
     5641 actagcaata ttttgtttta agtgttttct tctctgacta cgagcgtgct gtatgtcttt
     5701 tatatctatg gagtaatcag ctatttctgg acatatagca gtacaaagaa attcatctct
     5761 ataaaacaca cgtatttcag ccatatcatt tgggttataa cgaatcagta catattcacc
     5821 tacataagct tctagattag tattactgta tcgaaaacct tgaaaatgaa tgccatctga
     5881 atgaactttt ctagatttag gtatttccaa caataataaa tcaagttgtt ctaagctact
     5941 tggcatatta gggaaaaagt gattactatt ccaatgactg ataggcgtgg tatgaatagt
     6001 actatgttct ttttgattat aatcttcaat taaaaagtaa cgtaattttt cttcaaaatt
     6061 gtgaaaattt attagattac taggagtatc attattgttt atatatccag gcagttgttc
     6121 taagaaagtt tgattaactg tctgaaagaa tcgttctatt tttccacgac cacgaggaac
     6181 accaactttc gaaaacatca agttaatttt caaatcaata gcgacttgtt ccatatgatg
     6241 tgaagtaaag tcacttccat gatctgtgta gaatttttcg ggtataccac acactggcca
     6301 attggtatca tttttattcc atattgcttg gtgtagtgtt aatgctgtgt tttgagcatt
     6361 ggggggcatc aaaacttaag aaatagcctg caattgcacg actatagtca tccataataa
     6421 tagttagcca tggtctattg atattacctt tttggtctaa tataaagata tctagcaaag
     6481 tatggtctgc ttgccatatt tcattgggtc tcgaggattc tctaatttgt attaaatcgt
     6541 acttattttg atagtatttt tcaccctgat gagagaaatc aataacagac ttaggcatcg
     6601 ctttaataac actataaatt tgtttataac ttggtatatc aaaattattt tctttacagt
     6661 aattagtgat tttcctatga attgtggcta tactatttct tttattcata agcgcaaggc
     6721 gttcaatttc atcaattatc tttggttcta ttttacgtgt tcctttatca gctcttgtcg
     6781 catagattag tcctttaagt ccttgttctt tatatgactt attccaccta taaagggtgc
     6841 ttaacgcaat ccctttactt ttagaaatac ttgataaaga ttgttcgcct aggataaaag
     6901 gttttataat attgtacttt tgagtagctt ttttacgttt ggcttcagaa aaattagtta
     6961 gatacttctc cttgtttttc atcttccttg tcctccaatt tattgaggta acgataaatt
     7021 gttgtacgtg aaacatgcca ctgttctgca attgtcttaa ttggcgtgcc attatcataa
     7081 agggtcttaa gtaagtttaa atctttttga tttaattttt ctggtctgcc tccatatcgg
     7141 cctctagcac gtgctgcaat tcggccagct gaagaacgct ctaaaattaa attacgttca
     7201 aattctgcaa atgctgcgaa taaatgaaat aataattgtc cagttgaact tgatttatcc
     7261 attgttatat tttcttctaa actatggaaa cttacacctc gttcgttaag ctcattaact
     7321 aatgtgatta aatcctccat attacgtccc aatctatcta atctccaaac aacaatcgta
     7381 tctcctgacc tcgcaaattc aattgcttta tctaaaccag gtcttttact ttttgaacca
     7441 ctcatatggt cattaaatat cttttcacaa ccatatgtat ttaatcgatc ctcctgtaaa
     7501 tttaaatttt gtaatccagt tgaaactctt gcataaccta ttttcaaaat acaaacctcc
     7561 tatatacatc ttcagtgtac cataacttaa ttacaaggtc ttttatgaac atagattttt
     7621 tgttgggttt ttgaacacat aatcctatgt aattcttact tatttagaca taaaagaaga
     7681 gtgtacagaa aatggttatt ttctgtacac tctcatcttt aataatatat tttaaatgtc
     7741 attaacaaaa ctaatttaat aagagtcaag catagtttac atatgtatta tgtttgaaac
     7801 atacctctaa ttacttttta ctaatatcat ttaaaatatc tcgcaattct tcaatttctt
     7861 tgttatttaa ttcttcattt ttcgcaaaat tcaacactaa acttttcata tcccctccat
     7921 acagtttatt aagaaaggtt ttagcagttt tcattttaat atcgtcttct ttaatatttg
     7981 atgagtaaaa ataaatattt tctgatttgt atcgttttat aatctctttt ttatatagtc
     8041 ttgtgattaa tgttctaatc gttttatcac taacttcttt atatttttga atttcaacta
     8101 caatttcatt agctgatact gattttttat cccatattat attcataaca tcccattcag
     8161 ccatagatat ttcaacttgc ttattggcca tttaaaacac ccattccttt taatattttt
     8221 tcacttatta attcagcatt tttcccagac gggtttccat ctgataaatg tgtagcaaaa
     8281 taatacttat catgatttgt aattacgtaa cctacaaacc acccattatt atacttcccg
     8341 tttactatac ctgtacctgt tttcccatac agttcatact tttcattttt cttaatcaat
     8401 aatgaagaag ataattgatt ctttgctttt ttactaaaat ggttattttg ttccatcata
     8461 tttttaaaaa ctattacttg ttcaagatta gatattttca aactatcttc catccaatag
     8521 cttttataac ttcccaaatt ttcattacca taatttaatt gcttgagttg agccgcagta
     8581 tagttctttg gtatttgatt actaatacgt tcgaagtacc aattaactga attttgcatt
     8641 gctgtattta aatcttgttc cttattccaa gactcgaaaa gataatgttt atgattccat
     8701 gacatacgtg aatttttatc acttataata tgacggtcaa gtccaaacag tgctaaataa
     8761 attttgtaag ttgaatcagg agaatatctt tttctacttt ctttttcatt ataaatatag
     8821 tatttgtctt tcttcatgct gtacataacg aaagatccac tatttgaacc aaaattttta
     8881 ctttcatcta aaatttggta atcgctttgt aagggctttt tataattata atcagttaag
     8941 gattgcccca ttaaaaactg gctttgaatt atcatgataa aaaaagtaaa aatacaaata
     9001 aaaattagaa ttaattttga ctgctttttc agatcggctt cttttatatt aattaatcta
     9061 tttttgagta atgatttttt accattaaat gaatggctta atatattttt gttgaaaaat
     9121 gaggttttta atacggagtc cataatagat tccgcataag ttttaaattc atttttgtta
     9181 atattattaa ggacaaatct atcggcttct acttcattgt catgaattat ctttcttttt
     9241 acaatatgta ctaatggatt gtaactcata ataatagaga agatattaaa gataattaaa
     9301 tgtaaagtat ctctattttt agcatgagca tattcatgca gtattatata ttttagtctt
     9361 ttatcaatta cacttttaaa atatgaacta ggaatcaaaa taatatattt cccataccaa
     9421 aaagttattg gagattgaat agcctctgct tttcgaatca caatattttt tttatattga
     9481 tggttgaaaa gtatcgtatc tattttattt ttttcatttt cgtttagata aagtgactgt
     9541 ttctttaaat atttaagata taataaggct ttcaaaaatt taaaacttaa aataataact
     9601 aaaactatcc aaataactgt gcagatatta tcaattgaat cccaattaaa cttatggata
     9661 tctgttgcga actcttgaac aggtttggtg gtaattatgt tatggttcaa gtcgtgtgac
     9721 ttactttcaa ctgtgggcgc ttgattattc acattattaa attttataaa agagaattta
     9781 attgggataa aaggaattaa tccagcaagc acagttagat accaaacttt ataatttaaa
     9841 ctataattaa aatagcgttt taatatgtac ctaaaaaata ctaacaatag aaatataaaa
     9901 caaaagctta ctacactcat tattagtaat ttagccattt tgacaccttc tttcaaatat
     9961 ttataataaa caattgacat caatattaca attgtaatat tattgttttg taaaaattac
    10021 aactgtaata tcggagggtt tattttgaaa aagttaatat ttttaattgt aatggcttta
    10081 gttttaagtg catgtaattc aaacagttca catgccaaag agttaaatga tttagaaaaa
    10141 aaatataatg ctcatattgg tgtttatgct ttagatacta aaagtggtaa ggaagtaaaa
    10201 tttaattcag ataagagatt tgcctatgct tcgacttcaa aagcgataaa tagtgctatt
    10261 ttgttagaac aagtacctta taataagtta aataaaaaag tacatattaa caaagatgat
    10321 atagttgctt attctcctat tttagaaaaa tatgtaggaa aagacatcac tttaaaagaa
    10381 cttattgagg cttcaatgac atatagtgat aatacagcaa acaataaaat tataaaagaa
    10441 atcggtggaa tcaaaaaagt taaacaacgt ctaaaagaac taggagataa agtaacaaat
    10501 ccagttagat atgagataga attaaattac tattcgccaa agagcaaaaa agatacttca
    10561 acgcctgctg ctttcggcaa gactttaaat aaacttatcg caaatggaaa attaagcaaa
    10621 aaaaataaaa atttcttact tgatttaatg tttaataata aaaacggaga cactttaatt
    10681 aaagatggtg ttccaaaaga ctataaggtt gctgataaaa gtggtcaagc aataacatat
    10741 gcttctagaa atgatgttgc ttttgtttat cctaagggcc aatctgaacc tattgtttta
    10801 gtcattttta cgaataaaga caataaaagt gataagccaa atgataagtt gataagtgaa
    10861 accgccaaga gtgtaatgaa ggaattttaa tattctaaat gcataataaa tactgataac
    10921 atcttatagt ttgtattata ttttctatta tcgttgacat gtataatttt gatatcaaaa
    10981 cctgattttc cctttattat tttcgagatt tattttctta attctcttta acaaactaga
    11041 aatattgtat atacaaaaaa tcataaataa tagatgaata gtttaattat aggtgttcat
    11101 caatcgaaaa agcaacgtat cttatttaaa gtgcgttgct tttttctcat ttataaggtt
    11161 aaataattct catatatcaa gcaaagtgac ataattgttg aatttatagt aactgaaacg
    11221 tatgattagg gtgtatatta attatgagat ggaaatcaat gattgttggc tatgcgagag
    11281 tatcatcgaa cgatcaaaat ttagaaagac aacttgaaaa tttaaagacg ttttgtgctg
    11341 aaaaaatatt tacagaaaaa cagtctggga aatctattga aaatagacca gtacttcaag
    11401 aagcacttaa ctttttgagg atgggagatc ggtttgtagt agaatccatt gattgtttag
    11461 gtcgtaatta tgatgaagtg attcataccg ttaattattt aaaagacaaa gaagtacaat
    11521 taatgattac tagcttacct atgatgaatg aagtggttgg caatccatta ctggataagt
    11581 ttatgaaaga tttaattatt caaatattag caatggtttc agaacaagag agaaatgaaa
    11641 gtaaacgtcg acaagcgcaa ggaattcaag ttgcgaagga aaaaggcgta tataaagggc
    11701 gccccttact ttattcacca aatgctaaag atccacagaa acgtattatt tatcatcgcg
    11761 ttgtagaaat gttagaagaa ggccaatcaa ttagtaaaat tgcgaaagaa gtaaatataa
    11821 caaggcagac gatttacaga attaaaaacg ataatgattt gatttaataa actttgtttc
    11881 aatgcaactg agagcttctc acagcgtctc aaaacagatg attataatct attatgagtt
    11941 tttaataata agacaagaaa agagagcgta aatatgctct ctctttttct cattaacgaa
    12001 tgtttataac gcaatcatga tgagagtatt aatacagtta attatttgaa atactttagt
    12061 ttatataatg ttgaattata ggtagtgaaa ttgtatttat tatacattgt catatcgttg
    12121 tttaatgata gttaatttaa ggataataga attaatatta tatatagatg aacaaaacaa
    12181 gcaacagagc agaaaaaaca cttttagatt atttttactc attctctatt ttatttattt
    12241 ttgctataat aaataaagaa tattaaatga aggtgttttt atgaaaaaga aatttgtttc
    12301 tagttgtatt gctagtacaa tcttattcgg cactttatta ggtgtaactt ataaagctga
    12361 agctgcaaca gtacatgtag ctggtggtgt ttggagccat ggtattggaa aacattacgt
    12421 atggtcttat tatagtcaca ataaaagaaa tcatggttca acagcagtag ggaaatattc
    12481 atcttttagt ggtgttgctc gacctggtgt tcaatctaag gcatctgctc caaaggcttg
    12541 gggtggaaac aaaacatttt atagtcttca ctaattacat atattaatta aggagaatag
    12601 acagaattaa gtaaacttaa ttctgtctat tctcttgaaa gaggcaatat gaaaaaattc
    12661 aaattatttt tagattttag tactttatta ttaatttcag ggctattatt tttatttttc
    12721 ttcaaagaaa atgaagaaat tatacctgaa agttccaata ttttaacaat ctctaattgg
    12781 gataaatcta acagtaaatc aaaagtgtta gatgtcattg aatcaggcgc caaaaatcaa
    12841 aatatacaaa taattaaatc cgttaaagat tttgataata aaaaagaatt ttttgttttc
    12901 aactcaaaac gaaataattc tgactttata cgtaataaaa catcactttt aactccatca
    12961 gatttattaa acagagagat aaaaggaaag tattatatta ttggtgaaca tttcaatgta
    13021 gaagagctta cgagtgaatt aaaaaaagct ggtttaacat ctgaagttga atacataaat
    13081 agaaacatat tattttttga attagtcata gataatgatt tattagtgcc tttcatattc
    13141 ttaggcgtat tatatctttt gtacttctta tatgacagag gatataattt gaaattttat
    13201 gctattcaaa agctacatgg cttttcaact acacgcatta tttttcataa tattcatata
    13261 aaaatcattt attggctagt acttaccgct attttcttta ttgctaatat attaatcatt
    13321 catatagcca atttagaatt ggatttctta atgtttattc gtagatttat cgtgttgctt
    13381 tttgtttttg cttgtattac tacattgctg tggctgattt cgtatagtct tcttttgaag
    13441 ttaagtattc cattaatctt aaaagggaaa aaaggatata agttttcaat atttatgggt
    13501 accttcacca aatgtatcat ggtgctaata ctatcttttt tactggcaca aaatttaaat
    13561 gcttatacga agttaaagaa tatatatgac tctgaaaaaa tctggcaaaa gttagataat
    13621 tactatacat tagagatttc tcctaatatt agaaattcag aagaaaaaca aattttagaa
    13681 actaatatat acaatttaat taagaaaagc gaacaacttg gtggattgct tttaaagaat
    13741 aataatatag ccaatcccga taaaaacaat tacattcctg aaaatggcaa tgtctttttt
    13801 atcaataaca attttctgaa tttctataaa aatataaatc atgattttaa aatgattgac
    13861 aatcattcgg ataaaataaa cgtgtttatt cctccaaggt tacaatatca aaaatctgaa
    13921 attcaaaaaa atcaccaagg atggattgac tttcaaaagc aacaaaacaa aaaagtagat
    13981 gtgcaagtac tgtcaaaaaa cgtatctgtt ttttcttttg atcgcacaac taatttgaaa
    14041 tttgggtatc tagattctcc aatagtaatg ttgttgacac ttgacgattt aacaggagat
    14101 ttttatttag ctgctgtttc tcaaggtgga tatctattta aagatttaga tacacttaaa
    14161 cagttgctta aagataatca cctagaagaa gaaattagcg gtataactaa ttacaaggat
    14221 tctgtgttaa atgaattaaa tgaaacgaaa acaaaaatga taataacaat agttactatt
    14281 attattaacg ttttcattct tttgatagct actgtatttg aaacaattca atattttagc
    14341 tggaataaaa agcaactatt attaagaaaa attcatggtt attcattatt cagcagtaat
    14401 gtacgttatt taacaatttc tatcttactt tctattatgt tagcttacac tacgcatatt
    14461 ttatttggtt caaagatatt actattcata ataatgtcta ttgctattat tcaacattta
    14521 cttcaaattg cttatattaa atatcttgaa aaatacttta aagatttaat gagggagatt
    14581 taaacaatga aaagaacttt aattattgta acaattgtac tattaatcat catacttagt
    14641 ctgttattgg ttagaaatga gcatttagat cgttttaacc cactgttaaa agaaaaagta
    14701 tcttatgcca aagttccaaa agatacccag gactatagaa atataactgt atactctaaa
    14761 aatggagaaa aaaagagtta taaattggat tttttaggtt atgatcctac aaaagaatat
    14821 gtgaaagtaa atcataaagg gaaatatgtg cgttcgatag aatacattac aaaagatatt
    14881 cctagctttt taaaatgagg tgaccgatag tgataaaact tgaaaatgtt tttgtaaaaa
    14941 aaggtaataa aaacatttta gacggatgta actttaattt tgaaaaagga aaatcatatg
    15001 ctttagttgg agaaagtggc gctggaaaat ctactttact taacataatc gctgggttcg
    15061 aagatgtatc acaaggaagc atatatattg aagataagtt actaaaaaag aaagtcgatt
    15121 tttatagata tacgttaggg tatttgtttc aaaattttgc tttacttgaa aatcaaacaa
    15181 tcagtcaaaa tttagattta gccctaaagt tcaaaaagaa taaaaaagat aatatgaact
    15241 taaagaaaga agtattaaaa aaggtcggcc tagatttaga tatcaagaga attgttagtt
    15301 ctctaagcgg tggtgaacaa caaagagtag cattggcaag attaatatta aaagatccga
    15361 aaatcatttt agctgatgaa cctactgggt cactagatac gaaaaatgga aaaatagtta
    15421 ttgatttatt attgaagcta cttgatgaaa ataaaactat gattgtcgta acgcatgatt
    15481 tagagcttgc gaaacgattt gatgtcatag tcaatatttc tgagcttaga agttaagaaa
    15541 tattgatagg tatagccata catagagaaa aaacaatatg aaatatgatt agtcattact
    15601 tttgagtttt ttaatttaag gactggattt tccagtcctt ttttatgatg acaaaaaaca
    15661 agcctcgcag agcacacgtt tttaatgact tatttggttt ttaataagtc tagtatgtta
    15721 aaacttttct gtgtttaggt gttataatca tatgcagtgg aagttgattt attatgtctt
    15781 attcaattat tcgagttgtt aaagtgaaat caaaaacaaa tacaagaggt attcaaagac
    15841 atattcaaag agaaaataaa aattatgaaa atatagatat tgatttaagt aagtcatatt
    15901 taaactatga tttagtcaat gatactaagt ttgattttaa taaaaaaatt gatgagaaaa
    15961 tcgaaaaaaa ttataaaggg aaacgcaaaa ttagaacaga tgccattaaa catattgatg
    16021 gattaattac atcagataat gtgtttttta atcaattatc tgaagaagag acaaaatagt
    16081 tttttaagca tgctaaagcg ttcttggaag aagaatacgg taaagaaaat cttttatatg
    16141 cgacagtaca tatggatgag ataacaccac atatgcatta tggcgtagtt cctattacta
    16201 aagatggacg tttaagtgcg aaagaagttg taggtaataa aaaagcatta accgaattcc
    16261 aagatagatt caatacgtat attaataagc aaggctatga tttaaaacga ggaatttcta
    16321 gacaacttac aaaagaaaaa catgatcaag ttagccgtta taaacaaaaa acagaatatc
    16381 ataaacaaat gcatatgcgc tagaagcaaa tagaggatta tttaaagcaa gaaaatgata
    16441 aattgataca aaactaccaa aaatcattag atacgcttaa aaagcttctg agtgtcatgt
    16501 atgaaattaa aactaaaaat gtaggtggat ggtttcataa agagaagcaa gaaacaggca
    16561 atattgtaat tactaaaact gattttgaaa aatacactaa acaaattaaa gcagcacaga
    16621 tgatattaga tgattatgaa tgtattaaaa gtgggaagtc attaaaaaaa gcagagaaac
    16681 aaaatgaaag tttagttaat gaattgacta gtgtccatat ggaaaatgaa aagctggttg
    16741 aagaatttaa tgatttagca caacgttata attatttgtt gtcagagaat gaaaagaaag
    16801 ataaagaact aaattatacg cttaagttat tcaatcaagt ttttaaaatc attaaaagta
    16861 tgatgaaaga agagcgttat catacactaa taaatcatat tgataatcat ttagacaatt
    16921 ctaaaatacg tgaagtaatg acgatagata acaatgatga acagttcttt aagaagaaat
    16981 atcaagcaca agaacgagaa atcattttta aagaagatag agaagatggt tatacattat
    17041 aaaaatagat atttaaatgc atttgtttga ggttaattat tttttaggat gaaaaatagg
    17101 tagcccccct cgaacttttt aatatatttt tataaatctt tttaaaaacc tttttagggg
    17161 cttgttcagc cctagagcaa caagggattt caatgcctaa aggagtgttt ttgccacata
    17221 aaaggagtgt ttttgccaca taaaaggagt gtttttgcca cataaaagga gtgtttttgc
    17281 cacataaaag gagtgtttta aaaagttgta ctccttttat ggtttgacat tgataataaa
    17341 gtagtttatt gtgaataaaa gttttcaaat gggagtgtat attcaaacga tactccttta
    17401 ggttcgtaat aaagggggct gtatcatgac aggagagaca gttgtatata aaaatgaaat
    17461 gaatttagtt ccattaaggc gatttacagc tactgaaatt aatttatttt ttgcgatgtg
    17521 taataaatta aaagagcaag atactaatac attacgtttg tcttttgatg aattaaaaaa
    17581 attaagtaat tatagtccag aaacacgtaa tattaataga tttgctaatg atttagataa
    17641 tgtgtataaa aagatgttga atttaaccat tagatatgaa gatgatgatg taatagaaag
    17701 attcgtttta ttcaatcatt atagaatcca taagcgagaa caatatctag aaatatcaac
    17761 ttcttcaaat ttaaaacaca tattgaattc aattactaat aattttacaa aatttgaatt
    17821 aaaagaaatg actaggctta aatctacata ttctaaaaat atgtttagat tacttaaaca
    17881 atacaaacat acaggctatt taaaaattca catcgatgat tttaaaaatc gtttagatat
    17941 acctaaatct tatcgtatga ctgatattaa caaaaatgtt tttaaaccta ttattattga
    18001 attaggttct atatttaata atcttactat caataaaatc aaagcgaaaa aagggcgtaa
    18061 aattgaatgg atagagttca catttgacgc tgagaaacgc attcataaca aacgacaacc
    18121 tcaaatgtcc aagatagata aatcaagaca atatgtgagg cgtgaaaaga cgcctaaatg
    18181 gttagaagaa cggtcatatg aaaagcaacc tcaaaaagat tacgacccac aattagagaa
    18241 agaacgagag gattttttaa aacaacttga actgaattgg gaataacgca acttttcgtt
    18301 gcgagttggt taactaaaag tatcgtgact tttcaattat tttaattata gtttgagtta
    18361 aggagtgatt ttatgaaatt agctgaagct ataaaagaac agagagaatt aaaaggatgg
    18421 tctcaagagg aattagccaa tatattaaag gtttccagac aaagtgtttc taaatgggaa
    18481 agtgccaaaa actatccttc cttagatatt ttgattgcta tgagcgattt attcggaatc
    18541 tctttagagc atttaattaa aggagatgca cgttttaaaa aagttatttt agagggaaat
    18601 tatagagaga gtaacagggt accttccata gttgattttc tttatgattt ttggtggctt
    18661 ttctttcctg ttgccggatt tttagtttgg gccattcatt cgttcatggg ttgattttaa
    18721 aatcaaaatt taatgcacat caggcaatat gaaaaaggaa agtattttta cgacaccttg
    18781 aaatgtattg ataagaatag aagagtttac aaaaggcaat atgaaatata tactaaaagt
    18841 aacaagaatt tcgtttgtaa acgcacaaaa ccccgaacta ttcgccgtag ttcggggttt
    18901 tgtggtgaat tggctttaat cgtctatatt attttttatc acgtttatgg agctaataac
    18961 caaataacgt aacgagacaa ccactgattg ccgttgtcat gatgtgaaca agaatttcat
    19021 tcataaatcg cacctcctct ctacgccgaa ttgacatctg agagatagac gaccttcaca
    19081 ttataacaaa tctctccttc catgaaataa catgaatatt aataaatgtt gttatatatt
    19141 aaagataaat aaatataagg gtgggattga taatgtttgg cgatcaaaga caagaagcta
    19201 caaaatatgt cattaaagaa ggttatcaag atatttattt cctcaacaaa aacggggaat
    19261 ggtattattt cgaagtaaga agtgtctggc gtggcaaaca tattattaga gttaaagatg
    19321 gtttgttagg ttggagaaaa gaaatagtaa ctgaataaag atacaaaata cttgccaatg
    19381 caaaagaatg aaaacgcgtc aaatcaacga tgtataaaag atgcataaaa gataatgaaa
    19441 gtaaaaagcc ataaatgccg tcatataggc atttatggct ttttgtttgg ttaacataat
    19501 cgatgattat cagaagttca attcacataa aaaagcacgg ctaatttatg aacttgtcgt
    19561 acctttttaa ttaaaattag ttaccaaata gacgactcca aaaccccttt ttaggttccg
    19621 tttcttcact cttttcttct atatcactat cattgtcatt tggattagct gaaacgtctt
    19681 ctctttgtgc ttcttcacct tgtgtacttt cgtcgctttg acttccagat atatccttat
    19741 attgaatctc tgtttcttta gtttcttcct gatctcggtt aatatttaca ggactagtag
    19801 tatatgtttt ttcttgtgca tcaacgtttt gtctagcgtt agtagatgta tcaaagggat
    19861 aattaaggtg tttttctttt tctaattgat tttctaattt ttgaatcttt ttattactct
    19921 ctaatgccag aacttgctga ttctcaagca attttgatct ttcttgcaac tcttttctgt
    19981 aaaattcaat tgttgtttca tgacgacttt cttgtttttc aatttgatta tttaaagtat
    20041 taatctgatt tttaagtatt tctactattt gagcatcgct tttagattca aaattaatat
    20101 tatccgactc ttttttttgt ttgtcttcag tagcactttc aaaaccatat ttctttttat
    20161 tttcatttac tctttgaatg attttttcta tatcggtatc ttctttaata aacgaagtgt
    20221 tttcctgttt tattgtctct atattcaatc tcttaatatt attaaaaatc gtttgcttac
    20281 taacccctaa ttcttcactc aaccttttta cacttttcat atcatcaacc ctttataaaa
    20341 tgtttataaa cccttagtaa aatattataa gcttataacg attaataata aagtaatcga
    20401 caaataaaaa tataaattcg ccaacctttt tatcaagggt ttgtaaaggg tttatggtgt
    20461 ttatcaaagg tttataaacc tatattttcc cttttttaag tttattcaaa gtgctataat
    20521 aaccttaata taacaaaaac cccaactact ggtaatagtc ggggtttggt aataaaacgt
    20581 ttagaaactg tttatttata taattttcga tacttagatt atataatgaa taatatctta
    20641 gtgcaagcac ctagattatt aaataaacac aaaaaatgta agcgttttat tacctcttac
    20701 caaactaaaa ttcggaaaga ggtttttatt
//
