LOCUS       NZ_CP070588            18779 bp    DNA     linear   CON 03-JUN-2024
DEFINITION  Escherichia coli strain ESC53083 plasmid p53083_IncFII.
ACCESSION   NZ_CP070588
VERSION     NZ_CP070588.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN16933302
            Assembly: GCF_016939795.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18779)
  AUTHORS   Kraftova,L., Finianos,M., Studentova,V., Chudejova,K., Jakubu,V.,
            Zemlickova,H., Papagiannitsis,C.C., Bitar,I. and Hrabak,J.
  TITLE     Evidence of an epidemic spread of KPC-producing Enterobacterales in
            Czech hospitals
  JOURNAL   Sci Rep 11 (1), 15732 (2021)
   PUBMED   34344951
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18779)
  AUTHORS   Bitar,I.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-FEB-2021) Microbiology, Charles University in Prague,
            Alej Svobody 1655/76, Plzen 1 32300, Czech Republic
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Microbial Assembly v. 1.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 250X
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016939795.1-RS_2024_06_03
            Annotation Date                   :: 06/03/2024 03:10:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,142
            CDSs (total)                      :: 5,029
            Genes (coding)                    :: 4,794
            CDSs (with protein)               :: 4,794
            Genes (RNA)                       :: 113
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 235
            CDSs (without protein)            :: 235
            Pseudo Genes (ambiguous residues) :: 0 of 235
            Pseudo Genes (frameshifted)       :: 105 of 235
            Pseudo Genes (incomplete)         :: 146 of 235
            Pseudo Genes (internal stop)      :: 46 of 235
            Pseudo Genes (multiple problems)  :: 55 of 235
            Pseudo Genes (short protein)      :: 1 of 235
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP070588.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..18779
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="ESC53083"
                     /isolation_source="stool"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="p53083_IncFII"
                     /geo_loc_name="Czech Republic: Hradec Krlov"
                     /lat_lon="50.21 N 15.82 E"
                     /collection_date="2019-09-19"
                     /collected_by="Fakultn nemocnice Hradec Krlov"
     gene            66..882
                     /gene="blaOXA"
                     /locus_tag="JW305_RS00530"
                     /old_locus_tag="JW305_00530"
                     /pseudo=""
     CDS             66..882
                     /gene="blaOXA"
                     /locus_tag="JW305_RS00530"
                     /old_locus_tag="JW305_00530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491311.1"
                     /GO_function="GO:0008800 - beta-lactamase activity
                     [Evidence IEA]; GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="OXA-1 family class D beta-lactamase"
                     /name="blaOXA"
     gene            1021..1653
                     /locus_tag="JW305_RS00535"
                     /old_locus_tag="JW305_00535"
     CDS             1021..1653
                     /locus_tag="JW305_RS00535"
                     /old_locus_tag="JW305_00535"
                     /EC_number="2.3.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002075262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B-3 chloramphenicol O-acetyltransferase
                     CatB3"
                     /protein_id="WP_000186237.1"
                     /translation="MTNYFDSPFKGKLLSEQVKNPNIKVGRYSYYSGYYHGHSFDDCAR
                     YLFPDRDDVDKLIIGSFCSIGSGASFIMAGNQGHRYDWASSFPFFYMQEEPAFSSALDA
                     FQKAGNTVIGNDVWIGSEAMVMPGIKIGHGAVIGSRSLVTKDVEPYAIVGGNPAKKIKK
                     RFTDEEISLLLEMEWWNWSLEKIKAAMPMLCSSNIVGLHKYWLEFAV"
                     /name="type B-3 chloramphenicol O-acetyltransferase CatB3"
     gene            1738..2190
                     /locus_tag="JW305_RS00540"
                     /old_locus_tag="JW305_00540"
     CDS             1738..2190
                     /locus_tag="JW305_RS00540"
                     /old_locus_tag="JW305_00540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)--rifampin ADP-ribosyltransferase Arr-3"
                     /protein_id="WP_001749986.1"
                     /translation="MVKDWIPISHDNYKQVQGPFYHGTKANLAIGDLLTTGFISHFEDG
                     RILKHIYFSALMEPAVWGAELAMSLSGLEGRGYIYIVEPTGPFEDDPNLTNKRFPGNPT
                     QSYRTCEPLRIVGVVEDWEGHPVELIRGMLDSLEDLKRRGLHVIED"
                     /name="NAD(+)--rifampin ADP-ribosyltransferase Arr-3"
     gene            2413..2760
                     /locus_tag="JW305_RS00545"
                     /old_locus_tag="JW305_00545"
     CDS             2413..2760
                     /locus_tag="JW305_RS00545"
                     /old_locus_tag="JW305_00545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter QacE delta 1"
                     /protein_id="WP_000679427.1"
                     /translation="MKGWLFLVIAIVGEVIATSALKSSEGFTKLAPSAVVIIGYGIAFY
                     FLSLVLKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIIAAFLLARSP
                     SWKSLRRPTPW"
                     /name="quaternary ammonium compound efflux SMR transporter
                     QacE delta 1"
     ARG             2755..3293
                     /name="sul1"
                     /gene="sul1"
                     /gene_name="sulfonamide resistant sul"
                     /tool="rgi"
                     /drug_class="sulfonamide antibiotic"
                     /identity="98.88"
                     /coverage="64.16"
     ARG             3279..3592
                     /name="sul1"
                     /gene="sul1"
                     /gene_name="sulfonamide resistant sul"
                     /tool="rgi"
                     /drug_class="sulfonamide antibiotic"
                     /identity="100.0"
                     /coverage="37.28"
     gene            3720..3992
                     /locus_tag="JW305_RS00555"
                     /old_locus_tag="JW305_00555"
     CDS             3720..3992
                     /locus_tag="JW305_RS00555"
                     /old_locus_tag="JW305_00555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004883563.1"
                     /translation="MDSEEPPNVRVACSGDIDEVVRLMHDAAAWMSAKGTPAWDVARID
                     RTFAETFVLRSELLGIASENGIYGHSRFCNTDFDDKLACLNLSGV"
                     /name="hypothetical protein"
     gene            complement(4174..5177)
                     /locus_tag="JW305_RS00560"
                     /old_locus_tag="JW305_00560"
                     /pseudo=""
     CDS             complement(4174..5177)
                     /locus_tag="JW305_RS00560"
                     /old_locus_tag="JW305_00560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229637.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS110-like element IS5075 family transposase"
                     /name="IS110-like element IS5075 family transposase"
     gene            5405..6610
                     /gene="chrA"
                     /locus_tag="JW305_RS00565"
                     /old_locus_tag="JW305_00565"
     CDS             5405..6610
                     /gene="chrA"
                     /locus_tag="JW305_RS00565"
                     /old_locus_tag="JW305_00565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004896675.1"
                     /GO_function="GO:0015109 - chromate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015703 - chromate transport [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate efflux transporter"
                     /protein_id="WP_000184001.1"
                     /translation="MTNNPTDDSRPWSVFLIFLRLGLTSFGGPIAHLGYFRAEFVTRRR
                     WLSERSYADLVALCQFLPGPASSQVGIAVGLSRAGYSGALAAWAGFTLPSAIALILFAL
                     GISSYGDYVSQGALHGLKVVAVAVVAQAVWGMARNLCTDGLRVTIMAIATCVVLLVPSA
                     WGQVGVIAIAGIAGRLLFKPAKVVEHDPLPITVSHRAGVLWLSLFFVLLIGLPVLAELM
                     PSQTMAMVDSFYRVGSLVFGGGHVVLPLLQAEVVPSGWVNNESFLAGYGAAQAVPGPLF
                     TFAAFLGASMNTAPSGWIGGIVCLLAIFAPSFLLVVGSMPFWERLRRNTGIQAALAGIN
                     AAVVGLLLAALYQPVWTSAIFQPQDFGLALVALVALMFWKLPPWLVVLGSGAAGWLLSV
                     AL"
                     /name="chrA"
     gene            6621..6925
                     /locus_tag="JW305_RS00570"
                     /old_locus_tag="JW305_00570"
                     /pseudo=""
     CDS             6621..6925
                     /locus_tag="JW305_RS00570"
                     /old_locus_tag="JW305_00570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000130000.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /name="PadR family transcriptional regulator"
     gene            <6969..7034
                     /locus_tag="JW305_RS00575"
                     /old_locus_tag="JW305_00575"
                     /pseudo=""
     CDS             <6969..7034
                     /locus_tag="JW305_RS00575"
                     /old_locus_tag="JW305_00575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229646.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /name="EAL domain-containing protein"
     gene            7152..>7877
                     /locus_tag="JW305_RS00580"
                     /old_locus_tag="JW305_00580"
                     /pseudo=""
     CDS             7152..>7877
                     /locus_tag="JW305_RS00580"
                     /old_locus_tag="JW305_00580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006939175.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /name="IS6 family transposase"
     gene            complement(8060..>8125)
                     /locus_tag="JW305_RS00585"
                     /old_locus_tag="JW305_00585"
                     /pseudo=""
     CDS             complement(8060..>8125)
                     /locus_tag="JW305_RS00585"
                     /old_locus_tag="JW305_00585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229646.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /name="EAL domain-containing protein"
     gene            8186..9392
                     /locus_tag="JW305_RS00590"
                     /old_locus_tag="JW305_00590"
                     /pseudo=""
     CDS             8186..9392
                     /locus_tag="JW305_RS00590"
                     /old_locus_tag="JW305_00590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110242.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="type II site-specific deoxyribonuclease"
                     /name="type II site-specific deoxyribonuclease"
     gene            complement(9426..10858)
                     /locus_tag="JW305_RS00595"
                     /old_locus_tag="JW305_00595"
                     /pseudo=""
     CDS             complement(9426..10858)
                     /locus_tag="JW305_RS00595"
                     /old_locus_tag="JW305_00595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288433.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /name="DNA cytosine methyltransferase"
     gene            <10957..11242
                     /locus_tag="JW305_RS00600"
                     /old_locus_tag="JW305_00600"
                     /pseudo=""
     CDS             <10957..11242
                     /locus_tag="JW305_RS00600"
                     /old_locus_tag="JW305_00600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558153.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /name="IS1 family transposase"
     gene            complement(11177..11882)
                     /locus_tag="JW305_RS00605"
                     /old_locus_tag="JW305_00605"
                     /pseudo=""
     CDS             complement(11177..11882)
                     /locus_tag="JW305_RS00605"
                     /old_locus_tag="JW305_00605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(11970..12936)
                     /gene="repA"
                     /locus_tag="JW305_RS00610"
                     /old_locus_tag="JW305_00610"
                     /pseudo=""
     CDS             complement(11970..12936)
                     /gene="repA"
                     /locus_tag="JW305_RS00610"
                     /old_locus_tag="JW305_00610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009652816.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid replication initiator RepA"
                     /name="repA"
     gene            complement(12979..13302)
                     /locus_tag="JW305_RS00615"
                     /old_locus_tag="JW305_00615"
     CDS             complement(12979..13302)
                     /locus_tag="JW305_RS00615"
                     /old_locus_tag="JW305_00615"
                     /inference="COORDINATES: protein motif:HMM:NF014444.4"
                     /GO_process="GO:0006276 - plasmid maintenance [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepA family replication protein"
                     /protein_id="WP_251301869.1"
                     /translation="MRCSWRCVFYYDPLSNKVLRSLREIALECGLATKSLSGEVSITRA
                     IRALESLEKDFEFVACSSDCYSTAEIFFTPKLFEFLGVFPLSLSEARTEVSGRQKQRQG
                     ECR"
                     /name="RepA family replication protein"
     gene            complement(13523..13606)
                     /gene="tap"
                     /locus_tag="JW305_RS25890"
                     /old_locus_tag="JW305_00620"
     CDS             complement(13523..13606)
                     /gene="tap"
                     /locus_tag="JW305_RS25890"
                     /old_locus_tag="JW305_00620"
                     /inference="COORDINATES: protein motif:HMM:TIGR03475.1"
                     /GO_process="GO:0006276 - plasmid maintenance [Evidence
                     IEA]; GO:0031556 - transcriptional attenuation by ribosome
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepA leader peptide Tap"
                     /protein_id="WP_193703692.1"
                     /translation="MYMLRKLQAQFLCHSLLLCNISAGSGD"
                     /name="tap"
     gene            complement(13812..14081)
                     /locus_tag="JW305_RS00625"
                     /old_locus_tag="JW305_00625"
     CDS             complement(13812..14081)
                     /locus_tag="JW305_RS00625"
                     /old_locus_tag="JW305_00625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016831067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication regulatory protein RepA"
                     /protein_id="WP_022631531.1"
                     /translation="MSQVVNGVTSSSKRPYRKGNPVSAAERQQKAVARKKATHKEVRVF
                     VRDKLKNQLQIMCENEGITQAAMIERLIERESAKLGIDVTTSHS"
                     /name="replication regulatory protein RepA"
     gene            complement(14217..14768)
                     /locus_tag="JW305_RS00630"
                     /old_locus_tag="JW305_00630"
     CDS             complement(14217..14768)
                     /locus_tag="JW305_RS00630"
                     /old_locus_tag="JW305_00630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase D family protein"
                     /protein_id="WP_015065550.1"
                     /translation="MNRTLRRCCLSGLISLSLFAPVPAVYAASIETGYSPEGTALQLVL
                     KTINSAQQEIRLMGYSFTSPEVAGALVRAKQRGLDVKVVLDWKANTGRQNKASLAAMNL
                     LVNAGIPVRTVSQYKIMHDKVIIADGRNVEVGSFNYTRAADRFNSENVLVVWDEPVVAQ
                     RYLQHWQTRWEMGKDWSSSY"
                     /name="phospholipase D family protein"
     gene            complement(14872..15125)
                     /locus_tag="JW305_RS25470"
                     /pseudo=""
     CDS             complement(14872..15125)
                     /locus_tag="JW305_RS25470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020316912.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            complement(15250..15870)
                     /locus_tag="JW305_RS00635"
                     /old_locus_tag="JW305_00635"
                     /pseudo=""
     CDS             complement(15250..15870)
                     /locus_tag="JW305_RS00635"
                     /old_locus_tag="JW305_00635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229682.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            complement(15926..16568)
                     /locus_tag="JW305_RS00640"
                     /old_locus_tag="JW305_00640"
                     /pseudo=""
     CDS             complement(15926..16568)
                     /locus_tag="JW305_RS00640"
                     /old_locus_tag="JW305_00640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229683.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            complement(16618..17221)
                     /locus_tag="JW305_RS00645"
                     /old_locus_tag="JW305_00645"
                     /pseudo=""
     CDS             complement(16618..17221)
                     /locus_tag="JW305_RS00645"
                     /old_locus_tag="JW305_00645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229684.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="PIN domain-containing protein"
                     /name="PIN domain-containing protein"
     gene            complement(17382..17972)
                     /locus_tag="JW305_RS25895"
                     /old_locus_tag="JW305_00650"
                     /pseudo=""
     CDS             complement(17382..17972)
                     /locus_tag="JW305_RS25895"
                     /old_locus_tag="JW305_00650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229685.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="fertility inhibition protein FinO"
                     /name="fertility inhibition protein FinO"
     gene            complement(18128..>18779)
                     /gene="traX"
                     /locus_tag="JW305_RS00655"
                     /old_locus_tag="JW305_00655"
                     /pseudo=""
     CDS             complement(18128..>18779)
                     /gene="traX"
                     /locus_tag="JW305_RS00655"
                     /old_locus_tag="JW305_00655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229686.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=3
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     acetylase TraX"
                     /name="traX"
     ARG             2414..2757
                     /name="qacEdelta1"
                     /gene="qacEdelta1"
                     /gene_name="quaternary ammonium compound efflux SMR
                     transporter QacE delta 1"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             1739..2187
                     /name="arr-3"
                     /gene="arr-3"
                     /gene_name="NAD(+)--rifampin ADP-ribosyltransferase Arr-3"
                     /tool="amrfinderplus"
                     /drug_class="RIFAMYCIN"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             1022..1650
                     /name="catB3"
                     /gene="catB3"
                     /gene_name="type B-3 chloramphenicol O-acetyltransferase
                     CatB3"
                     /tool="amrfinderplus"
                     /drug_class="PHENICOL"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             357..865
                     /name="OXA-320"
                     /gene="OXA-320"
                     /gene_name="OXA beta-lactamase; OXA-1-like beta-lactamase"
                     /tool="rgi"
                     /drug_class="cephalosporin; penam"
                     /identity="98.18"
                     /coverage="61.23"
     Typing          complement(13524..13729)
                     /name="IncFII"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.517"
                     /coverage="100.0"
                     /evalue="2.36e-102"
ORIGIN
        1 gcctcattaa ttgttgccgt taaaattaag ccctttacca aaccaatact tattatgaaa
       61 aaacaataca tatcaacttc gctatttttt taataattgc aaatattatc tacagcagcg
      121 ccagtgcatc aacagatatc tctactgttg catctccatt atttgaagga actgaaggtt
      181 gttttttact ttacgatgca tccacaaacg ctgaaattgc tcaattcaat aaagcaaagt
      241 gtgcaacgca aatggcacca gattcaactt tcaagatcgc attatcactt atggcatttg
      301 atgcggaaat aatagatcag aaaaccatat tcaaatggga taaaacccca aaggaatgga
      361 gatctggaac agcaatcata caccaaagac gtggatgcaa ttttctgttg tttgggtttc
      421 gcaagaaata acccaaaaaa ttggattaaa taaaatcaag aattatctca aagattttga
      481 ttatggaaat caagacttct ctggagataa agaaagaaac aacggattaa cagaagcatg
      541 gctcgaaagt agcttaaaaa tttcaccaga agaacaaatt caattcctgc gtaaaattat
      601 taatcacaat ctcccagtta aaaactcagc catagaaaac accatagaga acatgtatct
      661 acaagatctg gataatagta caaaactgta tgggaaaact ggtgcaggat tcacagcaaa
      721 tagaacctta caaaacggat ggtttgaagg gtttattata agcaaatcag gacataaata
      781 tgtttttgtg tccgcactta caggaaactt ggggtcgaat ttaacatcaa gcataaagcc
      841 aagaaaaatg cgatcaccat tctaaacaca ctaaatttat aaaaatctaa tggcaaaatc
      901 gcccaaccct tcaatcaagt cgggacggcc aaaagcaagc ttttggctcc cctcgctggc
      961 gctcggcgcc cccttatttt caaacgttag actgcaaagt cacagaccgc gggatctctt
     1021 atgaccaact actttgatag ccccttcaaa ggcaagctgc tttctgagca agtgaagaac
     1081 cccaatatca aagttgggcg gtacagctat tactctggct actatcatgg gcactcattc
     1141 gatgactgcg cacggtatct gtttccggac cgtgatgacg ttgataagtt gatcatcggt
     1201 agtttctgct ctatcgggag tggggcttcc tttatcatgg ctggcaatca ggggcatcgg
     1261 tacgactggg catcatcttt cccgttcttt tatatgcagg aagaacctgc attctcaagc
     1321 gcactcgatg ccttccaaaa agcaggtaat actgtcattg gcaatgacgt ttggatcggc
     1381 tctgaggcaa tggtcatgcc cggaatcaag atcgggcacg gtgcggtgat aggcagccgc
     1441 tcgttggtga caaaagatgt ggagccttac gctatcgttg gcggcaatcc cgctaagaag
     1501 attaagaaac gcttcaccga tgaggaaatt tcattgcttc tggagatgga gtggtggaat
     1561 tggtcactgg agaagatcaa agcggcaatg cccatgctgt gctcgtctaa tattgttggc
     1621 ctgcacaagt attggctcga gtttgccgtc taacaattca atcaagccga tgccgcttcg
     1681 cggcacggct tatttcaggc gttatgcagc caaatcccaa caattaaggg tcttaaaatg
     1741 gtaaaagatt ggattcccat ctctcatgat aattacaagc aggtgcaagg accgttctat
     1801 catggaacca aagccaattt ggcgattggt gacttgctaa ccacagggtt catctctcat
     1861 ttcgaggacg gtcgtattct taagcacatc tacttttcag ccttgatgga gccagcagtt
     1921 tggggagctg aacttgctat gtcactgtct ggcctcgagg gtcgcggcta catatacata
     1981 gttgagccaa caggaccgtt cgaagacgat ccgaatctta cgaacaaaag atttcccggt
     2041 aatccaacac agtcctatag aacctgcgaa cccttgagaa ttgttggcgt tgttgaagac
     2101 tgggaggggc atcctgttga attaataagg ggaatgttgg attcgttgga ggacttaaag
     2161 cgccgtggtt tacacgtcat tgaagactag tcctttgcat aacaaagcca tcaaaccgga
     2221 cgccagagat tccgcgcctg ttgcgcatgg cttcgccatt ttatgcgcaa taggcgcgcc
     2281 accctgtcgc cgtttatggc ggcgttagat gcactaagca cataattgct cacagccaaa
     2341 ctatcaggtc aagtctgctt ttattatttt taagcgtgca taataagccc tacacaaatt
     2401 gggagatata tcatgaaagg ctggcttttt cttgttatcg caatagttgg cgaagtaatc
     2461 gcaacatccg cattaaaatc tagcgagggc tttactaagc ttgccccttc cgccgttgtc
     2521 ataatcggtt atggcatcgc attttatttt ctttctctgg ttctgaaatc catccctgtc
     2581 ggtgttgctt atgcagtctg gtcgggactc ggcgtcgtca taattacagc cattgcctgg
     2641 ttgcttcatg ggcaaaagct tgatgcgtgg ggctttgtag gtatggggct cataattgct
     2701 gcctttttgc tcgcccgatc cccatcgtgg aagtcgctgc ggaggccgac gccatggtga
     2761 cggtgttcgg cattctgaat ctcaccgagg actccttctt cgatgagagc cggcggctag
     2821 accccgccgg cgctgtcacc gcggcgatcg aaatgctgcg agtcggatca gacgtcgtgg
     2881 atgtcggacc ggccgccagc catccggacg cgaggcctgt atcgccggcc gatgagatca
     2941 gacgtattgc gccgctctta gacgccctgt ccgatcagat gcaccgtgtt tcaatcgaca
     3001 gcttccaacc ggaaacccag cgctatgcgc tcaagcgcgg cgtgggctac ctgaacgata
     3061 tccaaggatt tcctgaccct gcgctctatc ccgatattgc tgaggcggac tgcaggctgg
     3121 tggttatgca ctcagcgcag cgggatggca tcgccacccg caccggtcac cttcgacccg
     3181 aagacgcgct cgacgagatt gtgcggttct tcgaggcgcg ggtttccgcc ttgcgacgga
     3241 gcggggtcgc tgccgaccgg ctcatcctcg atccgggatg ggatttttct tgagccccgc
     3301 accggaaaca tcgctgcacg tgctgtcgaa ccttcaaaag ctgaagtcgg cgttggggct
     3361 tccgctattg gtctcggtgt cgcggaaatc cttcttgggc gccaccgttg gccttcctgt
     3421 aaaggatctg ggtccagcga gccttgcggc ggaacttcac gcgatcggca atggcgctga
     3481 ctacgtccgc acccacgcgc ctggagatct gcgaagcgca atcaccttct cggaaaccct
     3541 cgcgaaattt cgcagtcgcg acgccagaga ccgagggtta gatcatgcct agcattcacc
     3601 ttccggccgc ccgctagcgg accctggtca ggttccgcga aggtgggcgc agacatgctg
     3661 ggctcgtcag gatcaaactg cactatgagg cggcggttca taccgcgcca ggggagcgaa
     3721 tggacagcga ggagcctccg aacgttcggg tcgcctgctc gggtgatatc gacgaggttg
     3781 tgcggctgat gcacgacgct gcggcgtgga tgtccgccaa gggaacgccc gcctgggacg
     3841 tcgcgcggat cgaccggaca ttcgcggaga ccttcgtcct gagatccgag ctcctaggga
     3901 tcgcctcaga aaacggaatc tatggtcact cccgtttttg caacaccgat tttgacgaca
     3961 agttggcttg cttgaatcta tccggcgtct gaatgggatt ttattcccgc gcctcgatga
     4021 gttccgcgcc tgatgaacct ccagaaaata tacggcttca atgagccttt ccgttttaca
     4081 ggttcctcaa caggccggtg ggccgttagt atcatcaata tcagtattcg caaaaccaga
     4141 tgaatgattg tttaaactgg tgtatttctg cctttatgct tcgtaagttt gctgtcgcgc
     4201 cgtcagtgcc caggctattc tggccagctt gtttgccaga gcacaggtga cgacaaagtt
     4261 gcttttccga cacaacaact ccctgaccca gtcggccaac ttgccagact ggtgttccag
     4321 tttttgtatg aataccctgg cacactgaac caacaaagtt cggatctttt tgttgccccg
     4381 cttgctaatc cctaacaatg tcgtccgacc tcccgtgctg tactgtcggg gtaccagccc
     4441 tgttgccgcc gcaaagtcac ggctgctggc gtactgcttc ccgtcgccaa tctcagttga
     4501 aatagtactg gcagtcagcg ttccaacgca gggaatactc agcaagcgct gtccaacctc
     4561 atcttcgtcc aactttcgtt tcaactgaga ttccagatct ttaatctgct caacaagata
     4621 gtgataatgc tgttgtaatt tcagcagtaa ctggctgaga taaagaggca aactactgtc
     4681 ctcaagaagg gtactcagtc gactaataac ggcagcacct cgcggaacgc tgataccaaa
     4741 ttccagcaga aaagcatgca tctgattagt tgttttcacc ttatcctgaa ccagggattc
     4801 acggacacga tgcagagctc gcattgcctg ctgagattcg gttctgggct gcacgaaacg
     4861 catagatgga cgtgatgctg cttcacagat agcttcagca tcaacgaagt catttttgtt
     4921 gcttttaacg aatgggcgga caaattgcgg tgatatcagc tttggaaaat gccctaactc
     4981 ttccagcttg cgtgccataa agtgagaacc gccacaggct tccatcgcga tggttgttgc
     5041 cgggcatgtc gccagaaatt cgattagctt tggtcggtga attttttacg gtaaacggcc
     5101 ttcccacgat gatcctgaca atgaatatgg aaagagttct tacccagatc gataccaata
     5161 agcgcaatgt tttccatgat ggttctccga atgaaagcct gtcctcagca tagtactggg
     5221 aaggagggag tgaccatctc attaaataaa gcacgctaag ccgtaagtaa gcgtgctcct
     5281 gtgaaagcca cagctaaaac tgcgtagtac acatagaggt atttttttct agatttatat
     5341 cgaatttcgt tatcgaattt cgcttattat tgatcaactc gttgcagatc atgaaggcga
     5401 aagtatgacg aataacccta ccgatgacag cagaccatgg tcggtctttc ttatttttct
     5461 gcggcttgga ttgacatctt ttggcggccc cattgcgcac ttgggctact tccgcgccga
     5521 atttgtcaca cggcggcgct ggctctccga acggagctat gctgacttgg tcgcgctttg
     5581 tcagttcttg ccagggcctg caagcagcca ggtcggcata gcggtaggac tgtctcgggc
     5641 tggatacagc ggggcgctgg ctgcttgggc tggcttcacg ctgccgtctg ccatagcctt
     5701 gatccttttt gcgctcggca tctccagcta tggcgattac gtctcgcagg gcgcgttgca
     5761 tggcttaaaa gtggtggctg tggccgtggt cgctcaagca gtatggggca tggcgcgtaa
     5821 cctatgcacg gatgggctgc gagtcaccat catggcaatt gctacctgcg tcgttttact
     5881 tgtgccgtcc gcgtggggac aggttggcgt gattgctatc gcaggcatcg caggccggtt
     5941 attgttcaag ccagcgaaag ttgttgagca tgacccccta cctatcacgg tcagtcaccg
     6001 ggccggcgtg ctttggctct cgctgttctt tgtcttgctg attggcctgc cggtgttggc
     6061 cgaactgatg ccaagtcaaa ccatggcaat ggtggattcc ttctatcgtg tcggatcact
     6121 ggtgttcggc ggtggtcacg ttgtgctgcc attactgcaa gccgaagtgg tgccctccgg
     6181 ctgggtcaac aatgaatcct ttctcgcggg gtacggggca gctcaagcgg tgcccggccc
     6241 tttgttcacg ttcgccgcgt ttcttggtgc ctcgatgaac accgccccgt cgggctggat
     6301 cggcggcatt gtgtgtctgc tggctatctt cgcgccctcg ttcttgctgg tcgtcggatc
     6361 aatgccattt tgggagcgtt tgcgccgcaa tacaggcatc caagctgcgc tggccgggat
     6421 caatgccgct gtagtcggct tgctgctggc cgcgctgtat cagcctgtat ggactagcgc
     6481 catctttcag ccgcaagact tcggcttggc attagttgcc cttgtcgcac ttatgttctg
     6541 gaagctcccg ccgtggctgg ttgtcctcgg tagcggtgca gctgggtggc tgttgagcgt
     6601 cgctctgtga ggcacaaaaa atgactgaca aagacctcta cggcggtttg atccgcctgc
     6661 acatccttca ccatgcagcc gaggaacctg tctttgggct ggggatcatc gaagagctac
     6721 gccgacacgg ctacgagatg agcgctggca ccgtgtaccc gatgctgcac ggcctggaaa
     6781 aaaaggctat ctgacctcac gccacgaacg caccgggcga cgtgaacggc gtgtttatga
     6841 catcactgaa caaggcagaa ctgcacttgc tgatgcgaaa acaaaggtca aggagctgtt
     6901 cggagagttg gtagaaggtg gttgagtttt tgcttctatg tcaggttgag ctatacccta
     6961 actggattgt cattttcaga agacgactgc accagttgat tgggcgtaat ggctgttgtg
     7021 cagccagctc ctgacagttc aatatcagaa gtgatctgca ccaatctcga ctatgctcaa
     7081 tactcgtgtg ggctctgttg caaaaatcgt gaagcttgag catgcttggc ggagattgga
     7141 cggacggaac gatgacggat ttcaagtggc gccatttcca gggtgatgtg atcctgtggg
     7201 cggtgcgctg gtattgtcgc tatccgatca gctatcgcga ccttgaggaa atgctggcgg
     7261 aacgcggcat ttcggtcgac catacgacga tctatcgctg ggtccagtgc tacgccccgg
     7321 agatggagaa gcggctgcgc tggttctggc ggcgtggctt tgatccgagc tggcgcctgg
     7381 atgaaaccta cgtcaaggtg cggggcaagt ggacctacct gtaccgggca gtcgacaagc
     7441 ggggcgacac gatcgatttc tacctgtcgc cgacccgcag cgccaaggca gcgaagcggt
     7501 tcctgggcaa ggccctgcga ggcctgaagc actgggaaag cctgccacgc tcaataccga
     7561 caaagcgcgc cgagctatgg tgcagcgatc accgaattga agcgcgaagg aaagctggac
     7621 cggagacggc ccaccggcag gtgagtatct caataacgtg atcgatgccg atcacggaag
     7681 ctcaagatac tgatcaagcc ggtgcgcggt ttcaaatcga tccccacggc ctatgccacg
     7741 atcaaggatt cgaagtcatg cgagccctgc gcaaaggaca ggctcgcccc tggtgcctgc
     7801 atcccgggca tcaggggcga gtgcgccttg tggagagagc ttttggcatt gggccctcgg
     7861 cgctgacgga ggccatggca tgctcaacca ccatttcgag cagccgcctg atcggcgcag
     7921 agcgacagcc tacctctgac tgccgccaat ctttgcaaca gagccccgcc gtgctagtct
     7981 gctcggtgat ggtggagtga agccaacccg caatcgagca tagtcgagat tggtgcagat
     8041 cacttctgat attgaactgt caggagctgg ctgcacaaca gccattacgc ccaatcaact
     8101 ggtgcagtcg tcttctgaaa atgacactgt ttgtatataa tcatgaaaaa atggtgagta
     8161 gagtttcagg gtaacagggg tgcttatgtc ggttttccac aactggctac ttgagatcgc
     8221 atgtgagaat tacttcgtct acatcaaacg cctttccgcc aacgataccg gcgcaacagg
     8281 tggtcaccag gtagggcttt atatcccttc aggtatcgtt gaaaaactct ttccgtctat
     8341 caaccatacc cgtgaactga acccttcggt ttttctcacc gcacatgtgt catcgcatga
     8401 ttgccctgac agcgaagcca gggcaattta ttataacagc cgtcattttg gtaaaacccg
     8461 gaatgaaaaa ggattacccg ctggggtaga ggcagcccac ttcaggatcc tgaaaataca
     8521 ggggctctga cgctcctggc tttcaagctt gatgagcaag ggggggactg taaggaagta
     8581 aatatttggg tatgcgccag cactgatgaa gaggacgtca ttgagaccgc tattggtgaa
     8641 gttatacccg gagcgcttat atccggcccc gcaggacaga ttctaggcgg actatctcta
     8701 cagcaagcgc cagtaaatca taaatatatt ctacctgaag actggcacct gcgctttccg
     8761 tcgggaagtg aaattattca gtatgcagcc agccattatg tgaaaaattc ccttgatccg
     8821 gatgagcaac ttcttgaccg ccggcgcgtg gagtacgaca tatttctatt ggttgaggaa
     8881 ctgcatgttc tggatatcat ccggaaagga tttggctctg tggatgaatt tattgcgctg
     8941 gccaattctg tcagcaatcg ccgtaaatcc agagccggga agtcgctgga actgcacctg
     9001 gagcatctat tcattgagca cggcctgcga cactttgcga cgcaggccat cacagaaggt
     9061 aataaaaaac ccgatttcct ttcccttccg caggggctta ccacgatact gagtttcccg
     9121 tagaaaatct gcgcatgctg gcagtcaaga ctacctgtaa ggatcgctgg cgtcagatac
     9181 tgaatgaggc cgataaaatt catcaggtgc atctgtttac actccaggag ggagtttctc
     9241 tggctcaata tcgggagatg cgggagtcgg gtgtcagatt ggtcgtgcca tcatctctgc
     9301 acaaaaaata cccggaggcg gtgagagctg agctaatgac gctaggtgcg tttattgctg
     9361 agctgacagg gctttacgca gatattccat agattatctc ccggcataaa taccgggagg
     9421 agcgatcaga ttcgttcaac cttgcacgaa tcggcattaa ccgctttcag gatataaggt
     9481 tcaagcagtt tggctacggc ttcaaacacg ggcaccacta cggagttacc gaactgcctg
     9541 tacgactgag tgtctgacac aggaatgcga aaaggcctgc catctacttt ttcaaaacca
     9601 taaggcgcgc gcactctcgc ggagtcagcc tgcggggccg atgcgcctga ttttcttcgt
     9661 tcgcgaagtc tgtttcacct gtggccatat cccagccacg gtctatcaga atttcagacc
     9721 cgtctttgtg atagcgagca gaaagcgtac gggcaatgct ttctttattt caggattaac
     9781 gaggccaaaa ccgaatccgt tacccttagc tgcgtgcttt ttggcgtagt tatagagata
     9841 ctcccagagt ttcggcgtca gtatatattt gctgtcaacc acgggttcca gcagttcgcc
     9901 aaatgacgga cgctgttccg gataaaaacg actaatatcg cgcagggtaa agccctggtg
     9961 aatgttcaga tcacggcgga aaccgaccaa aacgatacgt ttctcggtgc tgaggtaaaa
    10021 agtgctttcc gtcgataact ttaggatcgt ttttgcccat ctcagctgca tccgcaactt
    10081 catagcccag ttcgtcgagg gtatccatga tgactttaaa ggttttaccc ttgtcatggc
    10141 tcttcaggtt tttaacgttt tcaagaacaa agatggcagg tttttttgcg cggataatac
    10201 gcgccacatc gaagaaaagc gttccctgag cctcacattc gaaaccatgc gcgcgcccga
    10261 gcgagttttt cttgcttacg cccgcaaggc taaacggttg acaggggaaa cctgctagaa
    10321 gtacatcatg atccggcaca tgctcattaa tgtaagcata ggcatcgttt tcaggtactt
    10381 caggtttatc actgagcgtg acttcacgaa tatcgagatt gaaagtgtgt tcctgagcat
    10441 cgttaaacca gttagcttta tatgtgcgca cagcctcttt attccattca ctggtaaaaa
    10501 cgcactggcc accgatggtt tcgaagccct tccgtatacc tccaatccca gcaaacaggt
    10561 caataaaccg gaaggcatag tcagggtgat gtgcaggcgc ttccggaagc atttttcgta
    10621 gaagttcctc ttcggctaac gtcagcgtct taggtgagca cttaccatta atccagcgat
    10681 taagagtctc gcgactccac tcatttttac caacttttct aagcagttca gccacgtact
    10741 tctggtcata gatttccagc acctgcccga gcagcttttt atcattttcc tgtcgcagtt
    10801 gttcttccgc ttctgctttc tcaagcagat cctgcgccag taattcaaat tcagacatat
    10861 tgcctccatt gggtcttatg ggtgaaactg tatcactcat ttgacccaga ttgaatgttt
    10921 ttatctggat atttaaacag gtttattgtt aggtaacgca cgttggccac gctggagcgt
    10981 cttctgggcc tgctgtcggc ctttgaggtc gtggtatgga tgacggatgg ctggccgctg
    11041 tatgaacccc gcctgaaggg aaagctgcac gttatcagca agcgttacac tcagcgcatt
    11101 gagcgacata acctgaatct gagaggcact gttgcaaagt tagcgatgag gcagcctttt
    11161 gtcttattca aaggccttac atttcaaaaa ctctgcttac caggcgcatt tcgcccaggg
    11221 gatcaccata ataaaatgct gaggcctggc ctttgcgtag tgcacgcatc acctcaatac
    11281 ctttgatggt ggcgtaagcc gtcttcatgg atttaaatcc cagcgtggcg ccgattatcc
    11341 gtttcagttt gccatgatcg cattcaatca cgttgttccg gtacttaatc tgtcggtgtt
    11401 caacgtcaga cgggcaccgg ccttcgcgtt tgagcagagc aagcgcgcga ccataggcgg
    11461 gcgctttatc cgtgttgatg aatcgcggga tctgccactt cttcacgttg ttgaggattt
    11521 tacccagaaa ccggtatgca gctttgctgt tacgacggga ggagagataa aaatcgacag
    11581 tgcggccccg gctgtcgacg gcccggtaca gatacgccca gcggccattg accttcacgt
    11641 aggtttcatc catgtgccac gggcaaagat cggaagggtt acgccagtac cagcgcagcc
    11701 gttttttcca tttcaggcgc ataacgctga acccagcggt aaatcgtgga gtgatcgaca
    11761 ttcactccgc gttcagccag catctcctgc agctcacggt aactgatgcc gtatttgcag
    11821 taccagcgta cggcccacag aatgatgtca cgctgaaaat gccggccttt gaatgggttc
    11881 atgtacagct ccatcagcaa aaggggatga taagtttatc accaccgact atttgcaaca
    11941 gtgccgaaaa aatagctaaa tgatatccgt caggacggcg gagccagggc cagctccagc
    12001 tgatacaggt tctgaatggc cagctgctgc agccgctccg ttgtacacca gtaagcctcg
    12061 tctgccggca ttgtcttcag gatatgaagc gacatttcgt gaatctggcg ctcacgagaa
    12121 tatctggcca ggcggttagc tcgtttacgt tcggcgccac gctgccgacg gaacctcagt
    12181 gcatcgagag ttttttgacg gtaccagcgc tcacgtgctg cacacgggga gatctcctca
    12241 tcttcacgca gaatcccctc ctcgataaga cgacgacgct cttcgctttg ccggagcttt
    12301 ttttgttgtt ccgcatcaag tttttccaga tccactccca gcatctgaaa ccctaacgcg
    12361 gtgatataga cgtatttagg aagccaggta cgggattccc tgtcccagct attttcttca
    12421 gatacagcca ggacaccaaa acgaacctgt tcgtcaatca accgggacag acgtgagact
    12481 gttacctctg tttccggaat aacttttcca tgactgtctt tctggctgag ttcttttgcc
    12541 agacgagaaa tacacatacc gaccgtcagc ttgccggcat cacagaagct gatcagcact
    12601 ggccagatag catccagcag acgttgcttt tccggccgga agccataccg gcggccagcc
    12661 cgacgacgtt ccctgacgta cagcggatga agcgatacgt gcatacgcag tcgcacctca
    12721 ccagtggtgc gatctttttg aacaagacgg ttataggcgt gccccagctg gccccagttt
    12781 tttgtaatgc tccggtcgaa accaggtcgg gttttcacat ttgggttttg tggagtgctc
    12841 gccgcgccgg cgacgggtag atttcttctc cggggaaacc agaaaagatg ccacatggcc
    12901 gtcctctacc ccctgccaga aaacggatct gttcatccat atccactgac tccagtgttg
    12961 cggattgtgc gccattactc atctgcactc tccctgccgc tgtttttggc ggccagacac
    13021 ttcagtcctg gcttcgctca gagagagtgg aaatacgcca agaaattcga acagcttagg
    13081 ggtgaaaaaa atctcagcag ttgaatagca atccgatgag caggcaacaa attcaaaatc
    13141 tttttccagc gattccagtg ccctgattgc tcgtgtaatg gacacttcgc cagaaagaga
    13201 tttagttgca agtccgcact ccagggcaat ctccctgagt gagcgcagaa ctttatttga
    13261 caggggatcg taataaaaaa cacatcgcca tgagcaacgc attcatcgct ctgcggcgca
    13321 aaaatggggg tttacgtttt cgtattccgt cccctacgcg acatcgctga tgcgatatcg
    13381 aaactgaagc tttcagtgaa accattggct ttttaccata agtttcagcg agaaaggcca
    13441 gggagtgtag tcctggggaa ccgtgaaaac aggttcagga ttgtttacct gaacatactt
    13501 gcatgagctt tgttggttat gatcagtcac cgcttcctgc gcttatgttg cacagaagga
    13561 gcgaatgaca cagaaactga gcttgaagtt ttctgagcat gtacatatac tccctgcata
    13621 gagcaacagc ttctatgcag tttatgaggg ccccgttaat cttttccttc cgccaagatt
    13681 gaagaagatt atcggggttt ttactttctg gttccgggta aacatccaca aaaccagctc
    13741 cctgccacct tatggtgtgg ccagccaaga attctaaacg ttcagtaatc tagcactcat
    13801 agcaggcatg atcaagaatg tgacgtcgtt acgtcgattc ctagtttcgc agattccctt
    13861 tcaatcagcc tctcaatcat tgctgcctga gtaattcctt cattctcaca catgatttga
    13921 agctggtttt taagcttgtc ccgcacaaat actctcacct ctttgtgcgt cgcttttttt
    13981 cgggcaacag ctttctgctg acgttctgcc gcagaaacag ggttgccctt cctataggga
    14041 cgtttagatg aggaagtaac tccgttaacg acctgtgaca tctctgcctc ctcaagcata
    14101 taactgaata cttgaacaaa gatactacac gtcgctggat gcagcgagag ttacgttatt
    14161 ttttgttata taacctgccc ttgttggcgc aatgagcagg ctattgagcg aggaggttaa
    14221 tacgaggaac tccagtcttt tcccatctcc caccgagttt gccagtgctg gagatagcgt
    14281 tgagcaacga ctggttcatc ccacacgact agcacgttct ctgaattgaa ccgatcagcg
    14341 gctcgagtgt agttaaaaga ccccacttca acattacggc cgtcagcaat aatgacttta
    14401 tcgtgcatga ttttgtactg cgacactgtg cgaaccggga taccggcatt gaccagaaga
    14461 ttcatggccg ccagactcgc cttgttttgc ctgcctgtat tggctttcca gtccagaacc
    14521 actttcacat cgagaccacg ctgttttgcc ctgacaagcg cgccggcgac ttcgggtgag
    14581 gtgaaggaat agcccatcag ccggatttcc tgctgtgcag aattaatagt cttcaggacc
    14641 agctgcagag ccgttccttc cggcgaatac cccgtctcga tgctggcggc atacacggcc
    14701 ggaactggtg caaacaaaga caggctgata agcccggaca gacaacatct gcggagcgta
    14761 cggttcattt ttttcacagt atttccttaa cgggtgttta agaaacgccg ggagcgggga
    14821 aactggcttt tccccgttcc cgaggttgga caacgacgcg atgcggaggc gtcaggattt
    14881 tgtggtatga cgaaaccagt agcagacggg tccgtcgccg gtatcgtgga cagatcccag
    14941 aaaccagcca tcatcatccg gtggctccgg tatccagcca cgggcattcg gggcttcatc
    15001 cgtaaatccg gcagcgaagc ttcaggcgct tcatcgcgca ttgttatcaa aagcactgga
    15061 gtttatgcgg ttctgagcag taagcttaat tactgacgga agtttcacat gccacttcgt
    15121 accagcgcag gatgtgtccc acgtaccctc tgcttccatc acgttgtcac ttcggcggcg
    15181 agtaatacat ttttcatttc tcttgcgctt tcagtatgac tcttgtcgcg ttgaacttgc
    15241 ataccacgat tatgagattt ttcggactgc atcggctccg cggtatttca gaactctccg
    15301 accctttctt accaggactc tccgtaatcc cgatcgcgtc agtagtggaa ttgccggcta
    15361 tgcctcagaa cctcttccag acagaatatc gcgccggatt acggtgtttt ttcttgtgct
    15421 gaggcagtca tccagttcaa ctgcgccgat gatagcgaag cgtgtatgga tggtcaacga
    15481 tgacccacat cgcagtgacc actgtgatgc caatccggaa gagttgccac cagtgtccgg
    15541 gcacttccgt ggcctggata tggggagaga gtgtggcaat atctgccacc cggacctgag
    15601 gacacaacag ccagcgtgtt cggctggtat gcctcagcaa tgcccggaaa aatgttgttc
    15661 ccgtggcgtc atcagtgtgt cattacccac ccagacccgc tggcgacaca accgttgctc
    15721 agcctctgag gggcgaatac ccagggcttt cagtgacctc agaaccgggg aagtcttcgt
    15781 tactgcgcgt cctttcagaa gcagcaccag aaatcccagc aaactcagca caacaacggt
    15841 actgcccgcc atcattaata tctttgccat gtattttatt ccctgatgtt cctttctttc
    15901 ccgatgcgtt ttcctgtcgt cttcctcatc tttctgtccc tcttctgata aggcagaact
    15961 ctgccggcag cctgtcgagc aacgcgcggc gaaatacatt cggcagtcct ctcccggcta
    16021 caacatcagc aatcagaact gatagacgct aatctgcagg aagtggcaca ggacaaaacc
    16081 aatctgatgc accagtttcc gcagcaggca tattacgaag agcattaatc agccggatgg
    16141 catcctgtgg ggaaccccag gcgagaatac gataccgacc agcatcaccg ccggcgtata
    16201 caacagcccc ggctgataac ccgtccggtc aggcctgtaa gctcacacct ttgctggcga
    16261 aacatctcat catcccggag gatttcccat tccagccggg ccttttcatg gcgcggcacc
    16321 tcggccacca cctgaatacc gtcgcgaata ctgaccagcg gtgagacctc tggctttctc
    16381 atccggtcga tgtgccgggt gtacagggca aggcctgccc agaacagcgc gacagataac
    16441 gcaaccagat aaaatccgct tgcccgggat acaggagaaa ataaaaccat ctgaaccagt
    16501 gccagcgcgc agccgtataa ataacagaat aactgctgct cagggcgcag aatgaaatat
    16561 ctgaacatat tgattccttt ttagataaaa ataacattca cagccgtctt aatttcatta
    16621 tcgccagacc actgttttct catacaccgc aatcacacca cgcctgatta attcctcttt
    16681 aacgcgcgac cataaagcgc catgcctttt gtattaccgg acagggattt aatataattc
    16741 atcagggatg aagtattcgc cgggcggttc cctgcagatt ttttacttaa tgactggact
    16801 ttatcggtca ggtgcagcac ttcatcgtta ctgattacca taggtgccgc cttcggtttc
    16861 tctgcagagc aaggcgatga tatacggcaa catcgtctcc ccccctgcat agctcggcaa
    16921 tgacgccatc atagccttta tcattcgaga taatatgaaa tatcatctct tccggtgcag
    16981 tcgcgctaag tcttcccagc tcaacaccag atggaagtcc acattatttt tttgacacat
    17041 tcgcaacctg gaatacgctt accgatatat cacctgcata cgttacagct ggaaaacgta
    17101 taaactcctg ctgaggcccg gtaaataaaa taaggcgttc ataacgggac agacggacac
    17161 tttcaagtgt accaatattt tcataatcta cgagagcaat aattttttca gtcatcgtca
    17221 tccagaatct gtctgcacgg acagttatga tgccgcagcc tgtaatgcgg caaatataaa
    17281 atgaatacct gttgctattt caggcatacc ctcagctaat tttcgttaca tctattagct
    17341 gaggattccc aggtataatt atcaggaatg ggtaaatata attaaagggt ctgactcatc
    17401 tttcgttcag cccgcagcag ctccttcatc atgcgctcac tggcgtactg cgcttcctct
    17461 gcagtgacgg tcgcgacggc attcccctgc agatcatagc gggaggcccc accttcatcc
    17521 gggacagata gcccgcagac cgggtcagac tcttcaggca cttaatgacc tgtttatgcg
    17581 acaagcggca ggtcgcggtt cacaatgtcg gcgaacagct gttcgcgcat acccgttgcc
    17641 agcagacggg gtgagtttcc gtcgaacagc tgtggccaga atgccttcag ggtcatgatg
    17701 gcctgttccg gcggcagcag gcgaagataa tgcaccggag gtggcgtctt taccgcttta
    17761 accggcaccg cgcagcgttg cgcgcggcgg cttcggccgc ttgtttaacc ttctcaagtt
    17821 tctctttttt tgccttccag gccggcggga cgagaccacc acgaccttct ttcggcgcac
    17881 cacaccagga gcaggggtcg cctctgcgga ggtcgtactg ttctccgccg gttttcgttt
    17941 cagctcagta cagggcgttt ttcttcactc ataaggggcc atatcaataa aagctacagg
    18001 tctgaggtat acgatacgct aacggtatca tcgtttcacc tcgcaatgca gtggacaaca
    18061 acgatgatgt cccctttgtc acgtttacgg gcaatgtgcc cgcccccgga cctgtgtccg
    18121 gtttttttta catcgagacg acaataccga gtaccgccag gtgcacggca tagaacatca
    18181 cgaagaactg ccgcgccaga agcgtttcac acgttctccg gcagatgagc acaccatcag
    18241 cgtcagcagc gcaatcgcca gccggccact gattcactca cgtcatgcat attcatcagc
    18301 aacaccatga gggcccacag caccccgtat cccagccgtt ccggtgcatg ctgtgcgcga
    18361 caaagcagcc agctgcgggg tgagcatgcc ccacctccgg ccatgccgta gctgccggtt
    18421 gacaggggta tccaggtacc agcagtccag ccgccgggag ggtgtaatac caggacggct
    18481 ggctgaccca ccgcaggacc tggcccgtaa cggcaaaggc aaacagaata ttcccggtat
    18541 accacggtat ccaataagca taaacgacac ctgggcgacc agcgcccagc cccacaggct
    18601 gtttcagttg agacctggcg tatttccgcg tgccgggcca gattcattcc ccatgccaga
    18661 ccgaacagcg gaaaaacaac cacgtcccag caggcgcatc acttcattgt ttccggccag
    18721 cagtaagccg gtgtggtcag tcaccatcag taccagtgcg accgttttaa tcatatccg
//
