LOCUS       NZ_CP070570            40918 bp    DNA     circular CON 29-APR-2024
DEFINITION  Proteus mirabilis strain PM52260 plasmid p52260_1, complete
            sequence.
ACCESSION   NZ_CP070570
VERSION     NZ_CP070570.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN16933295
            Assembly: GCF_016939715.1
KEYWORDS    RefSeq.
SOURCE      Proteus mirabilis
  ORGANISM  Proteus mirabilis
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Morganellaceae; Proteus.
REFERENCE   1  (bases 1 to 40918)
  AUTHORS   Kraftova,L., Finianos,M., Studentova,V., Chudejova,K., Jakubu,V.,
            Zemlickova,H., Papagiannitsis,C.C., Bitar,I. and Hrabak,J.
  TITLE     Evidence of an epidemic spread of KPC-producing Enterobacterales in
            Czech hospitals
  JOURNAL   Sci Rep 11 (1), 15732 (2021)
   PUBMED   34344951
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40918)
  AUTHORS   Bitar,I.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-FEB-2021) Microbiology, Charles University in Prague,
            Alej Svobody 1655/76, Plzen 1 32300, Czech Republic
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Microbial Assembly v. 1.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 250X
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016939715.1-RS_2024_04_29
            Annotation Date                   :: 04/29/2024 03:50:21
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,063
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,857
            CDSs (with protein)               :: 3,857
            Genes (RNA)                       :: 109
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 83
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 31 of 97
            Pseudo Genes (incomplete)         :: 68 of 97
            Pseudo Genes (internal stop)      :: 18 of 97
            Pseudo Genes (multiple problems)  :: 16 of 97
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP070570.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..40918
                     /organism="Proteus mirabilis"
                     /mol_type="genomic DNA"
                     /strain="PM52260"
                     /isolation_source="sputum"
                     /host="Homo sapiens"
                     /db_xref="taxon:584"
                     /plasmid="p52260_1"
                     /geo_loc_name="Czech Republic: Nymburk"
                     /lat_lon="50.18 N 15.03 E"
                     /collection_date="2019-08-06"
                     /collected_by="Nemocnice Nymburk"
     gene            complement(join(40690..40918,1..329))
                     /locus_tag="JW301_RS19455"
                     /old_locus_tag="JW301_19455"
     CDS             complement(join(40690..40918,1..329))
                     /locus_tag="JW301_RS19455"
                     /old_locus_tag="JW301_19455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221001.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001217881.1"
                     /translation="MRIFGYARVSTSQQSLDIQIRALKDAGVKANRIFTDKASGSSTDR
                     EGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMG
                     QMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTGATE
                     IAHQLSIARSTVYKILEDERAS"
                     /name="recombinase family protein"
     gene            492..3497
                     /locus_tag="JW301_RS19460"
                     /old_locus_tag="JW301_19460"
     CDS             492..3497
                     /locus_tag="JW301_RS19460"
                     /old_locus_tag="JW301_19460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495017.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn3 family transposase"
                     /protein_id="WP_015586051.1"
                     /translation="MPVDFLTTEQTESYGRFTGEPDELQLARYFHLDEADKEFIGKSRG
                     DHNRLGIALQIGCVRFLGTFLTDMNHIPSGVRHFTARQLGIRDITVLAEYGQRENTRRE
                     HAALIRQHYQYREFAWPWTFRLTRLLYTRSWISNERPGLLFDLATGWLMQHRIILPGAT
                     TLTRLISEVREKATLRLWNKLALIPSAEQRSQLEMLLGPTDCSRLSLLESLKKGPVTIS
                     GPAFNEAIERWKTLNDFGLHADNLSTLPAVRLKNLARYAGMTSVFNIARMSPQKRMAVL
                     VAFVLAWETLALDDALDVLDAMLAVIIRDARKIGQKKRLRSLKDLDKSALALASACSYL
                     LKEETPDESIRAEVFSYIPRQKLAEIITLVREIARPSDDNFHEEMVEQYGRVRRFLPHL
                     LNTVKFSSAPAGVTTLNACDYLSREFSSRRQFFDDAPTEIISRSWKRLVINKEKHITRR
                     GYTLCFLSKLQDSLRRRDVYVTGSNRWGDPRARLLQGADWQANRIKVYRSLGHPTDPQE
                     AIKSLGHQLDSRYRQVAARLGENEAVELDVSGPKPRLTISPLASLDEPDSLKRLSKMIS
                     DLLPPVDLTELLLEINAHTGFADEFFHASEASARVDDLPVSISAVLMAEACNIGLEPLI
                     RSNVPALTRHRLNWTKANYLRAETITSANARLVDFQATLPLAQIWGGGEVASADGMRFV
                     TPVRTINAGPNRKYFGNNRGITWYNFVSDQYSGFHGIVIPGTLRDSIFVLEGLLEQETG
                     LNPTEIMTDTAGASELVFGLFWLLGYQFSPRLADAGASVFWRMDHDADYGVLNDIARGQ
                     SDPRKIVLQWDEMIRTAGSLKLGKVQASVLVRSLLKSERPSGLTQAIIEVGRINKTLYL
                     LNYIDDEDYRRRILTQLNRGESRHAVARAICHGQKGEIRKRYTDGQEDQLGALGLVTNA
                     VVLWNTIYMQAALDHLRAQGETLNDEDIARLSPLCHGHINMLGHYSFTLAELVTKGHLR
                     PLKEASEVENVA"
                     /name="Tn3-like element Tn3 family transposase"
     gene            4074..5540
                     /locus_tag="JW301_RS19465"
                     /old_locus_tag="JW301_19465"
     CDS             4074..5540
                     /locus_tag="JW301_RS19465"
                     /old_locus_tag="JW301_19465"
                     /inference="COORDINATES: protein motif:HMM:NF013211.4"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140911 - pore-forming activity [Evidence
                     IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA];
                     GO:0050829 - defense response to Gram-negative bacterium
                     [Evidence IEA]; GO:0031640 - killing of cells of another
                     organism [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like pore-forming protein"
                     /protein_id="WP_012368891.1"
                     /translation="MSKNNHSAETDHLSVTADRPSKGDLGSGPVGKGDGGDRNIISLSD
                     PNASFSYTTSTIEGLEGLNFTVTVHGARIINPQNGHTTNNIEVDGKGNSVDYKKNNVQN
                     NQLELPIPYNNKLARDRDLGRLTSRIRKDYFDLKNNKARVSIYNGHYIHTVTFDDAGNV
                     QNISEEYIEKTYNRYSKGIPNEKKDRLEEVKRFAILGYKTEPSNILDYNVKIKEYEFIF
                     TLNKLGFIEKFSKKIIKASQYESRQLNAFYKDLNIEQDEKKENLAKLMVVNAYQSYPQN
                     KKFIQDAEKEALMGAADIITNTGEKISKHLGEKYKTIANEIASDLRNFQGKKLRSLSDA
                     LKMMEKINRNPNIKIKQADRVVLANAVRHVDTKILSENFQRLGKSFGVLGKVLSVEKLR
                     EKAAIGFETGNWKPLMLEVEAMIISGYATGIAISIAISFISSIASFLAIGALPTTLAII
                     ATIMLISYLASLIDDKVVDKINNLLIPEAH"
                     /name="colicin-like pore-forming protein"
     gene            complement(6256..6558)
                     /locus_tag="JW301_RS19475"
                     /old_locus_tag="JW301_19475"
     CDS             complement(6256..6558)
                     /locus_tag="JW301_RS19475"
                     /old_locus_tag="JW301_19475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016149384.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_012368893.1"
                     /translation="MSVLFTKKAKEHIRTIRRYSLTHWGKNVAETYINCLRITIINIIE
                     KQPSIGIDRSDDLFTGIRSFPVESHIIYYREVENGIEVLAVLHQSQDPYIHIKRD"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(6567..6830)
                     /locus_tag="JW301_RS19480"
                     /old_locus_tag="JW301_19480"
     CDS             complement(6567..6830)
                     /locus_tag="JW301_RS19480"
                     /old_locus_tag="JW301_19480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011144651.1"
                     /GO_component="GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="WP_012368894.1"
                     /translation="MEIIPAQLAKNQFGDLLMKAQREPVQISKHGKRVAVVISPDEYDQ
                     FTQLKLQNLKSILAESIEQAERGELHHIDDVFAPLTSNEIEG"
                     /name="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
     gene            complement(6992..7117)
                     /locus_tag="JW301_RS20540"
     CDS             complement(6992..7117)
                     /locus_tag="JW301_RS20540"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_257792833.1"
                     /translation="MQKIVLLKCFLIVSILTKNKQWNFGGFNNRNLPVLAGREYE"
                     /name="hypothetical protein"
     gene            7377..8030
                     /locus_tag="JW301_RS19485"
                     /old_locus_tag="JW301_19485"
     CDS             7377..8030
                     /locus_tag="JW301_RS19485"
                     /old_locus_tag="JW301_19485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004666657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_049195410.1"
                     /translation="MILVFASDKGGVGKTTTAINMAVMLKRKNKSVIMLKADRNRDLFV
                     WSDIRAQAGFSAIPIHEAFGNISDEIKRLEKLCDVVVVDCAGHDSSEFRSALTVADVLL
                     TLVKPSSSLEKNTLTNVTKTVRTAQKQHGNSDLKAHVLMTRIKSHKLQDAVSLENELKS
                     DEIWLQPLKNRISELDIFENAVNAGVGVHEVEKASSLGVAKAQIELIAKEIGLI"
                     /name="AAA family ATPase"
     gene            8274..8555
                     /locus_tag="JW301_RS19490"
                     /old_locus_tag="JW301_19490"
     CDS             8274..8555
                     /locus_tag="JW301_RS19490"
                     /old_locus_tag="JW301_19490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004666658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix domain-containing protein"
                     /protein_id="WP_036896424.1"
                     /translation="MKLQKPDLDLTDSSTKTKNSTTQFIKAGDKRPTTSNKLIPSTFRL
                     PESAISILDTEAERAGQNKTAILKAAILAYSNLDENSKNLALLESFKL"
                     /name="ribbon-helix-helix domain-containing protein"
     gene            8916..9119
                     /locus_tag="JW301_RS19495"
                     /old_locus_tag="JW301_19495"
     CDS             8916..9119
                     /locus_tag="JW301_RS19495"
                     /old_locus_tag="JW301_19495"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_036896419.1"
                     /translation="MKQLTEFELEIIHAVVVLQELHDKPELSASVLKECNLSEIDCNEL
                     DDYEKDNLRIINKEYLVNLKGL"
                     /name="hypothetical protein"
     gene            complement(9204..9569)
                     /gene="ddp1"
                     /locus_tag="JW301_RS19500"
                     /old_locus_tag="JW301_19500"
     CDS             complement(9204..9569)
                     /gene="ddp1"
                     /locus_tag="JW301_RS19500"
                     /old_locus_tag="JW301_19500"
                     /inference="COORDINATES: protein motif:HMM:NF041452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA distortion polypeptide 3"
                     /protein_id="WP_049195411.1"
                     /translation="MSYLRQQFLTEEESKLLVILQENVKENYHVFCKVRLSEFLYSSQK
                     MGTSEFFNEFEIINSINLPFAIYDTLENQLVAAISYINPIEKSNLLENQDIKVIHLTML
                     KDTLTNGELSMFYSDSV"
                     /name="ddp1"
     gene            complement(9665..10069)
                     /locus_tag="JW301_RS19505"
                     /old_locus_tag="JW301_19505"
     CDS             complement(9665..10069)
                     /locus_tag="JW301_RS19505"
                     /old_locus_tag="JW301_19505"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_049195517.1"
                     /translation="MAKIYQFPQGKEKKEIQAKLKKSRSVKIKKDIKKSSLSHILSMLF
                     LGIRYFLGVTLDVLLLMVVSIISVFRYLIIPLGIFALILFYYNNEKMWNVEMTVTMALM
                     VSSLINPEVLQDIQPFQTLFGVKSPQSEAK"
                     /name="hypothetical protein"
     gene            complement(10079..11035)
                     /locus_tag="JW301_RS19510"
                     /old_locus_tag="JW301_19510"
     CDS             complement(10079..11035)
                     /locus_tag="JW301_RS19510"
                     /old_locus_tag="JW301_19510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006816367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_036896417.1"
                     /translation="MKTLRPKKYKEEEFFIADEVEISSFRDELASMEHPFFALKGGDDK
                     VREYRNNNISVLVRPATGIGLATVFDKDIWIYAISKLQQAIFEGKPISRTIAFTPYEFF
                     VTTNRDKGGRSYDELKKALERLAGTRIQTNIVYSSEKQETENFGLIDKWRILEEKKGRL
                     DIGMVEVTLPDWLYQGITKNKVLKINSDYFRIRKAIDRRIYEIARKHCGYQKSFSLSIE
                     LLHLKSGATSNKREFKRSIKKLSLVNDLPDYEVLLDAENDCVTFTNRHFDESLEKKMNQ
                     LAKNKNMIEEVVSNGKLPKKLQKKVATIADKISKEKR"
                     /name="replication initiator protein A"
     gene            11987..12502
                     /locus_tag="JW301_RS19515"
                     /old_locus_tag="JW301_19515"
     CDS             11987..12502
                     /locus_tag="JW301_RS19515"
                     /old_locus_tag="JW301_19515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025391.1"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="WP_036896414.1"
                     /translation="MNVQEALNIFGLSGELTEQDIKTAYKKAALKYHPDRNPLGAELMK
                     AINAAFDFLMNNLENINKFQSSDKNTHYNFTEELEEVLLTLSGLMGIIYEVIGNWVWIS
                     GETKEHKDTLKEIGCKWAAKKKQWFYRPEEHKSRRNRKEHSIDEIRTMYGTNGQRAATG
                     WQRVENRA"
                     /name="J domain-containing protein"
     gene            12553..13110
                     /locus_tag="JW301_RS19520"
                     /old_locus_tag="JW301_19520"
     CDS             12553..13110
                     /locus_tag="JW301_RS19520"
                     /old_locus_tag="JW301_19520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001178641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_036896412.1"
                     /translation="MKNFNECYQSVFEIVCRCLGDNWRINLLDNDAYRIKITSNRFMGF
                     SIHVREEKNRFSIMGSFDSRIHRGEIHSCTVSKDRNPVHIAEDIKRKIIVFAHDEINKA
                     KESKVKEQEKKEQDLIVKNMLSRLFTMHSSWQSGVIGAFKSDNGLDGMIRKTYSGYKIE
                     IDKLSVDNLIKLAGMITTLERG"
                     /name="hypothetical protein"
     gene            13113..13271
                     /locus_tag="JW301_RS19525"
                     /old_locus_tag="JW301_19525"
     CDS             13113..13271
                     /locus_tag="JW301_RS19525"
                     /old_locus_tag="JW301_19525"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_153274249.1"
                     /translation="MEIKRENFDSVFDINKWLKNNKDVKIINIETRKGNITDFTNSYTV
                     WFYVGSY"
                     /name="hypothetical protein"
     gene            13284..13514
                     /locus_tag="JW301_RS19530"
                     /old_locus_tag="JW301_19530"
     CDS             13284..13514
                     /locus_tag="JW301_RS19530"
                     /old_locus_tag="JW301_19530"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_036896410.1"
                     /translation="MIKLSKGSKNYYLTRENGQLVFIKNIKVRNKNDVKDGNKTAKKQV
                     YKIIVGIDLLPDEADRSILKSMLEQWKSEYE"
                     /name="hypothetical protein"
     gene            13507..13704
                     /locus_tag="JW301_RS19535"
                     /old_locus_tag="JW301_19535"
     CDS             13507..13704
                     /locus_tag="JW301_RS19535"
                     /old_locus_tag="JW301_19535"
                     /inference="COORDINATES: protein motif:HMM:NF042861.2"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin Xre-like helix-turn-helix
                     domain-containing protein"
                     /protein_id="WP_049195515.1"
                     /translation="MNELKRLRDKLGLSNSDLAELMGLSEQTIKNRMASDFNKKTASKL
                     EIEFLKLLAGEHEKYSILEK"
                     /name="antitoxin Xre-like helix-turn-helix
                     domain-containing protein"
     gene            13799..14131
                     /locus_tag="JW301_RS19540"
                     /old_locus_tag="JW301_19540"
     CDS             13799..14131
                     /locus_tag="JW301_RS19540"
                     /old_locus_tag="JW301_19540"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_036896473.1"
                     /translation="MKLFHVILNVTNDDFEKNIELKNFYEVAQSLNEVKEKFKIFKNAR
                     VSAIVVYDLFLEPVTVKFTMSAYNVHNQVIFCESQPTIVNNTLDLITKLNNYFKQDYLT
                     VDWKYI"
                     /name="hypothetical protein"
     gene            14412..14546
                     /locus_tag="JW301_RS20545"
     CDS             14412..14546
                     /locus_tag="JW301_RS20545"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_257792832.1"
                     /translation="MSDKMIAAAKDFAKGKRTTFPIMTVKELPFFLQQIRKESELLKH"
                     /name="hypothetical protein"
     gene            14935..15483
                     /gene="ddp1"
                     /locus_tag="JW301_RS19545"
                     /old_locus_tag="JW301_19545"
     CDS             14935..15483
                     /gene="ddp1"
                     /locus_tag="JW301_RS19545"
                     /old_locus_tag="JW301_19545"
                     /inference="COORDINATES: protein motif:HMM:NF041451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA distortion polypeptide 1"
                     /protein_id="WP_036896470.1"
                     /translation="MKQINFRINDNEYELYHKKVKENLNMSLPSFYKLVGNMMLNKDKD
                     IKETLSDHAISIGEESDYTDKRAYLYLTAEQENALITSAKKHGWSLSREMRFRLQTTLS
                     NEMDFFDQELQEMKLCRNHIKRIGLNINMILRRDEGRVLDKEGMRQDMQALTEQLNELE
                     NKFNYFINKCKGRIIANRL"
                     /name="ddp1"
     gene            15492..16655
                     /gene="mobP1"
                     /locus_tag="JW301_RS19550"
                     /old_locus_tag="JW301_19550"
     CDS             15492..16655
                     /gene="mobP1"
                     /locus_tag="JW301_RS19550"
                     /old_locus_tag="JW301_19550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006816359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobP1 family relaxase"
                     /protein_id="WP_036896467.1"
                     /translation="MGLDIEKEYRAKRARQESSRSVKSIKSAKSSFVHKVKNGGKFYDR
                     NAQESRIKKGASKEVMTKITGSAKVKQGVRNSVDYISRDDSLELVDEQGIKINAEEAKQ
                     SLIDSDDALQLSDKSRRTPDITKNIVFSPPMTAKVKPEEAIEAVRQTLIKKYPDNRFVI
                     AYHDDKKEHPHVHVILKTRKENEDKRIKITKQDLRDLRSGFCDELKLKGYDVKATHKQQ
                     IGLKSQLKDDSLTAPKRQKNVYEVIDFGRAPYQFNTKNKSQNYLTVKTLNKGVEATYWG
                     KEFGALCNREKIQKGDLIKLKKIGTEDIKIPKLDDKGQQTGWKITQRNQWEMQNLGVKG
                     VDRTKNILPENSGIKEIQQFQKQQTQFKQQAMELIKKEQQIKVGLKF"
                     /name="mobP1"
     gene            complement(16746..17033)
                     /locus_tag="JW301_RS19555"
                     /old_locus_tag="JW301_19555"
     CDS             complement(16746..17033)
                     /locus_tag="JW301_RS19555"
                     /old_locus_tag="JW301_19555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020317119.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_036896464.1"
                     /translation="MMYSVKFRKDAEKEWKKLDKTIQSQFAKQLIKRCENPHVASAKLR
                     NMPNCYKIKLRASGFRLVYQVIDDMLIIAVVAVGKREKSQVYNLASERLK"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(17030..17281)
                     /locus_tag="JW301_RS19560"
                     /old_locus_tag="JW301_19560"
     CDS             complement(17030..17281)
                     /locus_tag="JW301_RS19560"
                     /old_locus_tag="JW301_19560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010281712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="WP_036896461.1"
                     /translation="MPNTILSDTTASVSELKKNPMATVNAGLGYPVAILNRNQPAFYCV
                     PAELYEQILDALDDNELAKLVKERESQPLVDINLAEYL"
                     /name="antitoxin"
     gene            17686..18096
                     /locus_tag="JW301_RS19565"
                     /old_locus_tag="JW301_19565"
     CDS             17686..18096
                     /locus_tag="JW301_RS19565"
                     /old_locus_tag="JW301_19565"
                     /inference="COORDINATES: protein motif:HMM:NF017542.4"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA];
                     GO:0006276 - plasmid maintenance [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication/maintenance protein RepL"
                     /protein_id="WP_036896458.1"
                     /translation="MNLKEVNLEDWHLVHKVTGECIGIDILKTQDGGSFNKVFLNELAS
                     IIGCTGNGSEKVLGWILKNKNNQNEIHGTQREIAKEESVGVATVARVFKALKDNGYLKQ
                     KRSGTYLLNPSVIHYGGVGNRLTILRVWNDLI"
                     /name="replication/maintenance protein RepL"
     gene            18351..18617
                     /locus_tag="JW301_RS19570"
                     /old_locus_tag="JW301_19570"
     CDS             18351..18617
                     /locus_tag="JW301_RS19570"
                     /old_locus_tag="JW301_19570"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_142836830.1"
                     /translation="MKSDEIITLVEKCDIFDGKKLSFKQKEIAIRYVFGQTAEELAMHF
                     DNSTRSIWLHLDVVRNEFGNVSLSSLRTIIFMKLICQFINIKI"
                     /name="hypothetical protein"
     gene            18773..18955
                     /locus_tag="JW301_RS19575"
                     /old_locus_tag="JW301_19575"
     CDS             18773..18955
                     /locus_tag="JW301_RS19575"
                     /old_locus_tag="JW301_19575"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_036896454.1"
                     /translation="MKNSKTHITLAVPDDLNAWINFKSKDQNRSKRNFLLHLIEEARTK
                     DLSKRQPLNLDNDIL"
                     /name="hypothetical protein"
     gene            18952..19566
                     /locus_tag="JW301_RS19580"
                     /old_locus_tag="JW301_19580"
     CDS             18952..19566
                     /locus_tag="JW301_RS19580"
                     /old_locus_tag="JW301_19580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006816352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_036896450.1"
                     /translation="MIKETLLSLALQCAPLVHPDTAHDIAKVESGFNPYAIAEIKAKGK
                     VISHLPKTKNEALNIISRLKTSNARYSVGLMQIYSGNFKGFEVTPEELLDSCRNLNIFE
                     KILVDCYQRGGSLANALSCYYSGNFKTGKKKETQFANTSYIERIGISDNKNNYIVPSTK
                     NYKEENQEVAKAESDVVIEKLKPSNKIVYPRYVMRGVVKEN"
                     /name="lytic transglycosylase domain-containing protein"
     gene            19609..19863
                     /locus_tag="JW301_RS19585"
                     /old_locus_tag="JW301_19585"
     CDS             19609..19863
                     /locus_tag="JW301_RS19585"
                     /old_locus_tag="JW301_19585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006816351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_237074012.1"
                     /translation="MCGLMSLIAFTFPAQAADVTTATTGFLDRIIDFLTTIRKPAITIC
                     ALGIGFIALFARNHMAWIYPLIIGIIIFIIAPYLPDWLG"
                     /name="TrbC/VirB2 family protein"
     gene            19924..22695
                     /locus_tag="JW301_RS19590"
                     /old_locus_tag="JW301_19590"
     CDS             19924..22695
                     /locus_tag="JW301_RS19590"
                     /old_locus_tag="JW301_19590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006816350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB3 family type IV secretion system protein"
                     /protein_id="WP_142836829.1"
                     /translation="MSTVFKGLTRPALIRGLGVPLYPFLFTCVLCVLLGVWIHEALYFL
                     IIVGIFVIRKIMKIDERYFELIYLRYLVMGNPVSNQKYHAVHVGGNDYDRVDLSDVENF
                     MKLSDQASLEKLIPYSSHITDDLVLSQNRDLIATFELSGAYFECVSENDLSLMVDQLNT
                     LIRSYEGKPVTFYTHRIRNKKQVKAEFNSPIPFANRVMNAYYGSLTKSDFYQNRLFLTV
                     CFKPFSLEEKVAQFLSSKKKNKQKDKSILAEPINEMNEICARLTNYLSRYKAHRLGVYT
                     ENDRVFSSQLSFYQYLLSGQWQPVRVTNSPFYTYLGGKDIFFGGDAGQISISEPMRYFR
                     IIEIKDYFQDTESGIFDSLMYMPVEYTLTTSFTPLDKREAIQKLDDQREKLEMTDDAAK
                     SQITDLEVAVDMVSSGYLSMGHSHLTLCVFADSPDELVKNTNMVTGALQDLGLILSYST
                     LSLGAAFFSQLPGNYTLRPRLSILSSLNYAEMECFHNFFTGKETGNTWGNCLLTLKGSG
                     NDIYHLNYHMTTEYQNFFGKNPTLGHSEILGTSNAGKTVLMMMQACALQQFGSETSFPP
                     NSKVKKQTTIFFDKDRAGEVAIRAMGGDYYKVKLGEPTGWNPFAMPATKRNLIFLKDLI
                     RNLCTLNSEKGLTEYQNKLISDAVERLMQREDRSFGISKLIPLIMEERTEETLRDGLKI
                     RLAAWKQGGEFGWVFDNATDDFDISDKTIFGIDGTEFLEDAILSQVVPFYLIYKITLLA
                     DGRRLTLYFDEFWQWLANMLTAMMIYNKLKTGRKLNMVIVFATQSPDELLKSPMISALR
                     EQLATHIYLANPNAKKSEYVDGLQVNELYFNKIKKIDPLSRRFLVVKNPQRKGDSQDFA
                     AFASLELGEAAYYLPILSASTEQLEIFDEIYQDGMKPDEWIDIYLERANQAA"
                     /name="VirB3 family type IV secretion system protein"
     gene            22705..23472
                     /locus_tag="JW301_RS19595"
                     /old_locus_tag="JW301_19595"
     CDS             22705..23472
                     /locus_tag="JW301_RS19595"
                     /old_locus_tag="JW301_19595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006816349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_049195405.1"
                     /translation="MNKFKLTLISMVFGASFMASAGIPVAIDANPEWAIEAGRWSEKLK
                     QWSDTVKHYNAQIQSYQDELLAKTGIRDVQQLIQDAQSIKNDLTAIYNQGNAFIDKYAQ
                     NPTEAFSQQAQALLSKYNVSKTCANKGYVGDAIKGCEAQFLSILSVSEYGDSLQKQLEQ
                     DNSRMESLIKQVQNAKDPKATADAANAISFEQLKFEKLQFQYQMYRDKQRDLAEYKEQL
                     NQANFRDKQLKAVDSQPSYLDAYHKSQFDEEFQ"
                     /name="type IV secretion system protein"
     gene            23472..23723
                     /locus_tag="JW301_RS19600"
                     /old_locus_tag="JW301_19600"
     CDS             23472..23723
                     /locus_tag="JW301_RS19600"
                     /old_locus_tag="JW301_19600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006816348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="WP_036896444.1"
                     /translation="MKTKLLIGAVSILFLSACGEEVKSVQWWQEHADEAQKKVTECSSN
                     GNDSENCRNAKDGLFRHKQLTAKSPSFMDAYKKTQNKE"
                     /name="EexN family lipoprotein"
     gene            23731..24765
                     /locus_tag="JW301_RS19605"
                     /old_locus_tag="JW301_19605"
     CDS             23731..24765
                     /locus_tag="JW301_RS19605"
                     /old_locus_tag="JW301_19605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_052124780.1"
                     /translation="MENATATSDFFQTAYQVIWDMLNKTVANKVSEYSQIAADLAQYGI
                     SIYILWFAFSTLALKNKTPVPDFIWNLARFTIILMFIKNSGGWLSASTDAIYGLRDTLA
                     GGDPWKWMDQLWVKTSQVAAHIMSKDTSTYVKVDGGIGSFLTYFGGLAALLTCSFVFFA
                     AEITLLLLTTTAPIFILCLMFGFLRQMFNNWLQLIFSSLFIVMFGSLALRAGMSFLNIV
                     LSVSVAQAAEANLMQLGATAAAAGLFMVFVMILAKNFATQLAGVGVDGAVQGMAMMGVA
                     GAAVMAFKGIRKAGNTASNMGKSNRDRGWNGASASGNSGSSAPNSAKSRRQASIDNVRK
                     RYGT"
                     /name="type IV secretion system protein"
     gene            24767..24892
                     /locus_tag="JW301_RS19610"
                     /old_locus_tag="JW301_19610"
     CDS             24767..24892
                     /locus_tag="JW301_RS19610"
                     /old_locus_tag="JW301_19610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012368872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="WP_142836828.1"
                     /translation="MKKYLILVVFLLTACQSNKLLPKVTGELQPINTAEVMKNEK"
                     /name="conjugal transfer protein"
     gene            24955..25197
                     /locus_tag="JW301_RS19615"
                     /old_locus_tag="JW301_19615"
     CDS             24955..25197
                     /locus_tag="JW301_RS19615"
                     /old_locus_tag="JW301_19615"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_036896441.1"
                     /translation="MSGIIIAVIFFVIGFFVSVVINIIVSGSEKEKIKNFITIYKEYDV
                     KITDSSCRLSCDKGYIEVETKNYLSFIQRGGRYEK"
                     /name="hypothetical protein"
     gene            25187..25906
                     /locus_tag="JW301_RS19620"
                     /old_locus_tag="JW301_19620"
     CDS             25187..25906
                     /locus_tag="JW301_RS19620"
                     /old_locus_tag="JW301_19620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006816393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_205507947.1"
                     /translation="MKNKKVGIPFLKKKEKIELAKTFEEKDIKKQKIINTLYKIFGLSG
                     LAFAFLSLLGWIMMLPLKNTEVEIWTVDKNTGKTEKVSRVKDENLTKDEALGRYFVTQY
                     IKAREGYNYFRLQHDYDMVMLWSAENVANDYTAIFKTDARPTIVYKKAQRTVDIEIIYP
                     VFINPSSQKGDPDLLATVRFKKIIKDVTTNRSVEETWVARMTYRFMPDVEKKESERNAN
                     PLGFVVTSWVAEKEIRG"
                     /name="type IV secretion system protein"
     gene            25909..26826
                     /locus_tag="JW301_RS19625"
                     /old_locus_tag="JW301_19625"
     CDS             25909..26826
                     /locus_tag="JW301_RS19625"
                     /old_locus_tag="JW301_19625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006816392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbG/VirB9 family P-type conjugative transfer
                     protein"
                     /protein_id="WP_036896436.1"
                     /translation="MKKKSLLLLLAVFLSQQSTAEILPSASRYDPRNQVVNFNPLNTTV
                     INSAIGYITTVVFDDDEKVIDAQTGYEQGWDISKADNRVYIRVLPVKQVVEEMADNGKV
                     EQKEIALDPETDLSRWQTNLFVVTTKRNYSLELNAKTFKEPKKIAFVVNYRYPDEKRKQ
                     QNEIEQQRLAEYQRQQETAKINRELENAKTPKNWQYYQRVAKGSEMIMPDYAYDDGRFT
                     YFGFNPNKKMPSLFSQIGEQETITNPTIEKRGNYTVLVAHQVNDRWILRLGDQVIGIEN
                     KGLGKVRLSNSDTVSDNVVKEVIQ"
                     /name="TrbG/VirB9 family P-type conjugative transfer
                     protein"
     gene            26823..28007
                     /gene="virB10"
                     /locus_tag="JW301_RS19630"
                     /old_locus_tag="JW301_19630"
     CDS             26823..28007
                     /gene="virB10"
                     /locus_tag="JW301_RS19630"
                     /old_locus_tag="JW301_19630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006816391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB10/TraB/TrbI family type IV secretion system
                     protein"
                     /protein_id="WP_036896434.1"
                     /translation="MSEDTEKPLTAVEIEQKLKQERQLQIDQSSENKESTPEPKKVSLG
                     IDKLKKSKKGTVLLILFFVLSIGALSLYYFPSLLRAFISSDEAEEVPQETISTGGRDKL
                     TGLNNDVDPFGQAELNNAGELTTANTNEPAESTPPPPKRIEFSRGMDRGVSTRSSSTST
                     PSSSQNAPVETVSATTTQPETVVGSKTKITRLPYDPNLFIPENTAIPCSLDRRFVSDLA
                     GKLTCTVYEDVYSANGNVKLIDKGTVAHLVYKSAYVPNQGQGHVFLMATKLRTRTQPFI
                     DIPLVDSEAAGALGETGVDGWIDTHFWDRFGGAMMLGMIPDAMQGLNNVAKDNKDNQTD
                     YTANSRQAFSEIAKQAFANSVNIPPTLYKNQGEIITLITGSDLDFSSIYQLRMK"
                     /name="virB10"
     gene            28010..29041
                     /gene="virB11"
                     /locus_tag="JW301_RS19635"
                     /old_locus_tag="JW301_19635"
     CDS             28010..29041
                     /gene="virB11"
                     /locus_tag="JW301_RS19635"
                     /old_locus_tag="JW301_19635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006816390.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_036896431.1"
                     /translation="MREYHNQHLIHDLTQQFFAEYLNGVKGLTEIAVNEPNKLFLKVKG
                     RWEKREPKISYDDCLSFASTLADYHSDSIGDIKPVLSATLPHGERVQVVIPPACEKDKV
                     SITIRKPSNVFITHDDIVKSGFYSRVGQSFKSENASSDLVDLYHTGNFAAFIPECLRQG
                     KTMVFCGGTGSGKTTFSNAVMFYIPHHLRLISIEDTDETRFRFHENHVKLYYPSEGGNN
                     LITSASLLRACLRMNPDRILMTEIRGAETWDFLKASSSGHSGGVTTVHEEKPEDAILGM
                     VTRCYQNTECNNLPFNALVRKVLNNIDVIMSIKYLSDDDKRFASDIYFKDVHQNDYLAR
                     LLG"
                     /name="virB11"
     gene            29050..30882
                     /locus_tag="JW301_RS19640"
                     /old_locus_tag="JW301_19640"
     CDS             29050..30882
                     /locus_tag="JW301_RS19640"
                     /old_locus_tag="JW301_19640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053816.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA transfer
                     family protein"
                     /protein_id="WP_036896429.1"
                     /translation="MARKYPDKPQSIFIAIVMLGITYYAGSVIVYFLNGYDFLYIYKHY
                     QSDLLWQLISESRIKASIRVTAIPALLIGFVASFILPVAVIYLLNQEKMSLHGDAKFAS
                     DNDLKKSKLLKWEKENSKGILVGKYKGKYLWYTAPDFVSLGAGTRAGKGAAIGIPNLLV
                     WLHSLIILDPKQECWKITSKVREKLLGHRVYLVDPFNSKTHGFNPFFYIELDKESGAKD
                     LLKLVEILFPSYGSTGAEAHFNNLAGQYFTGLTKLLYFFIHHAPEYLKTFDVKPVFSIG
                     SVVDLYGRIDRELVLNNRQEIEAKARDENTLYHLQDGLTKLQEYHLTEDEQRSSVDGSF
                     RKKMSLFYLPTVRKCTDNNDFDLRQLRREKITIYVGINAEDLGIAYDFLNLFFNFVVEV
                     TLRENPDFDPSLKHSCLLMLDEFPSIGYMPIIKKGSGYIAGFNLKLLTIYQNVSQLNEI
                     YGIEGAKTLLSAHPCRVIYAVSEQDDAEQISAKLGYITTKSKGESKSQGRGSSKSKSES
                     EARRALVLPQELGTLDFKEEFILLKGENPVKAEKALYFSDNYFMDRLLKVSPKLEDEVK
                     KINKKSTVIGVKGLRYPDKEKMLSLGELESEVFL"
                     /name="type IV secretory system conjugative DNA transfer
                     family protein"
     gene            30879..31286
                     /locus_tag="JW301_RS19645"
                     /old_locus_tag="JW301_19645"
     CDS             30879..31286
                     /locus_tag="JW301_RS19645"
                     /old_locus_tag="JW301_19645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012368878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="WP_142836827.1"
                     /translation="MKKGLWLSVVLLTACSSPPEAPKVDWGKKEVAVNAKIMTWTPTHT
                     VVSSDVVNDEWQKRINNFIPENRLYDDAVYFAIAHSNKIIVEANNGTEFLKTKEWLQAH
                     GANGVIQYQKKSNWLNNPITVYLIKENQNEK"
                     /name="cag pathogenicity island Cag12 family protein"
     gene            31276..31824
                     /locus_tag="JW301_RS19650"
                     /old_locus_tag="JW301_19650"
     CDS             31276..31824
                     /locus_tag="JW301_RS19650"
                     /old_locus_tag="JW301_19650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010890138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_012368879.1"
                     /translation="MKSKIVAISLFFLPVLSQADVPVFTGDVKLACEAVLCLSSGTRPS
                     ECAPALSRYFGINKKFWSDTVNARKNFLQLCPASSDAGMPELVNAIANGAGRCDATYLN
                     KFLYEEKREQKCRSRGKEEDCWYETYYRIKNELPNYCRAYVNHEWTDLDSSLHYQGKME
                     WVKKESVAGWNNSGGRWVD"
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            32283..32549
                     /locus_tag="JW301_RS20475"
     CDS             32283..32549
                     /locus_tag="JW301_RS20475"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_202608422.1"
                     /translation="MDFNNRKIKKENRVYFNYTDDDAEKILKSKNAFYPDDELFSWIDE
                     GELVVEQYMSKDQVGRLVKQYMIETNGMPLKIVFPEYDKGSDQ"
                     /name="hypothetical protein"
     gene            32546..32893
                     /locus_tag="JW301_RS19660"
                     /old_locus_tag="JW301_19660"
     CDS             32546..32893
                     /locus_tag="JW301_RS19660"
                     /old_locus_tag="JW301_19660"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_142836825.1"
                     /translation="MKYLDLDPFAYGDNPEEANKLMELEFRELFDFISKQLKEERLIHI
                     LQENIGMNEQLSIHTYCKKRQNHYLPDDIDLHYLVNGNVLSKEDEDKIIEKVFKYRGGV
                     YVWKSNAKINK"
                     /name="hypothetical protein"
     gene            32908..34587
                     /locus_tag="JW301_RS19665"
                     /old_locus_tag="JW301_19665"
     CDS             32908..34587
                     /locus_tag="JW301_RS19665"
                     /old_locus_tag="JW301_19665"
                     /inference="COORDINATES: protein motif:HMM:NF025642.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfJ domain-containing protein"
                     /protein_id="WP_012368884.1"
                     /translation="MIKQNKILTLHELFKFCEANGVFRLVKVEENDSFVKIIICGVYQI
                     RLNKKTQKVTLHTWFFTNLESGEWRVRKSLPNRIPCFWKNENIYNIQYWLQSAVTHVID
                     SIVKSNYSISGICYMYKSFYGGIETKILLEDIQPDFDTTSEMFEEKTFFYPHYLAGMSM
                     SKMRHDICIKIMTRINAFINNETQKYASMSLSKNIWKVIDKGVFSLYGKAHFNSFVRNS
                     ILDANFLDYYKFSKQIRINDNVDYKGLWLMIGFLRKQKKSNYHYTLTGKIKDLYKELQL
                     PESISYGDFKYMYTLKPSLIAQLIEFISLRDRYRFGINDKIKIIMKLLRQPEIKKYPTK
                     AIFDFLETVWNGLRVEHGYTSVYRIALKWLDYHQDLYKNIGYKSVTRRWNTELNRFAHA
                     IEWVFNTDFYIQKNQSLASIYRLSEEWVEELNHDDYDYAEISPQWNGIDIDWQSCISEM
                     TVSEITTLEQLKKEGQEMHHCVYSYAHDCANETYRVFTIINNDERATLGISQVENHKIF
                     KFDQVMGVSNSAVSSEIIKMSKKVLNQVNSKINKVNLINLGE"
                     /name="PcfJ domain-containing protein"
     gene            34591..36909
                     /gene="topB"
                     /locus_tag="JW301_RS19670"
                     /old_locus_tag="JW301_19670"
     CDS             34591..36909
                     /gene="topB"
                     /locus_tag="JW301_RS19670"
                     /old_locus_tag="JW301_19670"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549937.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003917 - DNA topoisomerase type I (single strand cut,
                     ATP-independent) activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="WP_161745570.1"
                     /translation="MRVFIAEKPSLAKAIFEGLGGNPNTEKKKGYFQHGDDVVTWCVGH
                     MLELSDPQDYDEKYASWRFGDLPIKTVFPPTYKIKKETAAQTKIILSLIDQAKTIVNAG
                     DPDEEGCLLVNEILDYAKNKKPVERILVSDLNLAPVKKALADLQPNEKFRGMSNSALSR
                     SLLDQSFGYNLTRGCTLKGREKGYQGVLNVGRVQSAVLGLVNMRTLANQNHNESFYYDI
                     YALIEMNGHQVKAKYQTTDNDQIDDKRRLISEAQAKHITEIVSGQAVKVTIAATKAENT
                     KPPLPLNLSTLQQICAKRFGYAPQETLDIMQSLYETHKLLTYPRTDNRYLSDEHYYQAN
                     DIAQAVIGTLPELASTVEHMDKVQKHKAFNASKIEAHHAIVPTTKDGSNIQLNEKEKNV
                     YRLVSLYFIGLFYPDSIRDKTKVHFDIKGNTFTATQSVLVQSGWESLGKDSDEEETEEP
                     EKLDFDLSTLKFNDNGVCETANVDKKPTLPPKYFTASTLLSAMTRAAKFIDDPELRKIL
                     EAKDEGSTDQGSIGTEATRAGILKKLSENTGLISIEKEKGYSELVWKTTKQGQEFCAAL
                     PDEITKPDISARWAEKQALIKKGELTVADFIKETDSYIKELIAELDANGINITANGTPC
                     PVCQKGFLIKRKGQNGFFWGCSCYPECKTAFPDKNGQPVTEKQPNEGAVARLNVMCPSC
                     SNEIIIRPKGYFCTGCEFKIWAEFCSKKLTQNQVEKLIKDGKTAVIKGFKTKAGKTFDT
                     ELVLDDKKTGKIGFPEKKK"
                     /name="topB"
     gene            36954..37469
                     /locus_tag="JW301_RS19675"
                     /old_locus_tag="JW301_19675"
     CDS             36954..37469
                     /locus_tag="JW301_RS19675"
                     /old_locus_tag="JW301_19675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006816383.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0030527 - structural constituent of chromatin [Evidence
                     IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS family nucleoid-associated regulatory
                     protein"
                     /protein_id="WP_012368886.1"
                     /translation="MSELTREEKYKITSESLTGLTELRKFAKTKNFEWLENLANQLNGI
                     VEEQREEFELRKLELAELEEKRLKAIKYLEELGLDPETIHISVFETTDKKGKKRKSKNT
                     PAKYRFTHPETGKTDTWTGIGRMKKGLQLLIDAGHSLDEFLIDKASDAKDDIKEAEKLF
                     ENHPSSLG"
                     /name="H-NS family nucleoid-associated regulatory protein"
     gene            37441..38046
                     /locus_tag="JW301_RS19680"
                     /old_locus_tag="JW301_19680"
     CDS             37441..38046
                     /locus_tag="JW301_RS19680"
                     /old_locus_tag="JW301_19680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006816382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_223307256.1"
                     /translation="MKITLLRWVNLPLLLSLTLPVIGQCKPLFIGDSLTYELAMSYKKI
                     APVDAKFLESTGLQSKQILSWQDYTQNIDFSLYDTVYIVLGTNDLISKADIPEYQQKAS
                     VFIQTIKKQNRQIVWLLPPTLKNKEKNNLLSNTRIAICEAARKNKIKTMDTRVSLGYQY
                     SEFINGVKVRTSDGIHITENGADNVIRSLINVDKENNR"
                     /name="hypothetical protein"
     gene            38189..38983
                     /locus_tag="JW301_RS19685"
                     /old_locus_tag="JW301_19685"
     CDS             38189..38983
                     /locus_tag="JW301_RS19685"
                     /old_locus_tag="JW301_19685"
                     /inference="COORDINATES: protein motif:HMM:NF042758.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6685 family protein"
                     /protein_id="WP_240349994.1"
                     /translation="MVRGFPTEIKDIITNLCRIEKTIDYFFDFNKIQSLTASKSFGGIP
                     DGAINGSWFYDLYSWGRAMYPDERMKAENEDDWKRNIAHIESEGFRKCRPINVIYYEWL
                     NRFVAPNTGGSHHAALVVYQSIRDKIKYTRETILEKVSLNSYYIRMLDNEYYSFIINND
                     SNPKSLSESDKFINVITELISTHISILKPVHYYQNLMIIFIPKESLKIDSELFNNWINK
                     AHDQKKIINLPNYFRLPNEYHTKPYLHELRYLKMPNPNSIFQ"
                     /name="DUF6685 family protein"
     gene            complement(39052..39198)
                     /locus_tag="JW301_RS19690"
                     /old_locus_tag="JW301_19690"
     CDS             complement(39052..39198)
                     /locus_tag="JW301_RS19690"
                     /old_locus_tag="JW301_19690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001300273.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hok/Gef family protein"
                     /protein_id="WP_012368889.1"
                     /translation="MTKYALIGLIAVCLTVLCFSLLMRDRLCSISVNSGNTVVQATLSY
                     EER"
                     /name="Hok/Gef family protein"
     gene            complement(39647..40507)
                     /locus_tag="JW301_RS19695"
                     /old_locus_tag="JW301_19695"
     CDS             complement(39647..40507)
                     /locus_tag="JW301_RS19695"
                     /old_locus_tag="JW301_19695"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="broad-spectrum class A beta-lactamase TEM-1"
                     /protein_id="WP_000027057.1"
                     /translation="MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYI
                     ELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYS
                     PVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRW
                     EPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSA
                     LPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAS
                     LIKHW"
                     /name="broad-spectrum class A beta-lactamase TEM-1"
     ARG             complement(39651..40507)
                     /name="blaTEM-1"
                     /gene="blaTEM-1"
                     /gene_name="broad-spectrum class A beta-lactamase TEM-1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          15493..16652
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atggtgacca ccatttgccc catatcaccg tcggtactga tcccgtcgtc aataaaccga
       61 accgcgacac cctgagcatc aaactctttt atcagttgga tcatgtcggc ggtgtcgcgg
      121 ccaagacggt cgagcttctt caccagaatg acatcacctt cctccacctt catcctcagc
      181 aaatccagcc cttcccgatc tgttgaactg ccggatgcct tgtcggtaaa gatgcggtta
      241 gcttttaccc ctgcatcttt gagcgctctg atctgaatat cgagggactg ctggctggtt
      301 gagacccgcg cataaccaaa aattcgcata aaatgtacct taaatcgaat atcagacacg
      361 atgtgtctat tatgccaaaa tgacgattta atggacactc aaacgaagcc gttttactat
      421 gtctgataat ttataacatt tcggacggtt gcaaaaatgt tactaaatgc ccgtaaggca
      481 gggaggccta tatgcccgtt gactttctga ccactgagca gactgaaagc tatggcagat
      541 tcaccggtga accggatgag cttcagctgg cacgatattt tcaccttgat gaagcagaca
      601 aggaatttat cggaaaaagc agaggtgatc acaaccgtct gggcattgcc ctgcaaattg
      661 gatgtgtccg ttttctgggc accttcctca ccgatatgaa tcatattcct tccggcgtcc
      721 ggcattttac cgccagacag ctcgggattc gtgatatcac cgttcttgca gaatacggtc
      781 agagggaaaa tacccgccgt gagcatgcag cgctgatacg tcagcactat cagtatcgtg
      841 aatttgcctg gccctggaca tttcgcctta cccgtctttt atatacccgg agctggataa
      901 gcaacgaacg tcctggcctg cttttcgatc tggcgacagg gtggcttatg caacatcgta
      961 ttattctccc cggagccact acgctgactc ggttgatttc agaggtaagg gaaaaggcga
     1021 cgttgcgcct gtggaacaaa ctggcactga taccgtcagc cgaacagcgt tcacagctgg
     1081 agatgctgct ggggccaact gattgcagcc gcctgtcttt actggaatca ctgaaaaaag
     1141 gccctgtgac catcagtggt ccggcgttta atgaagcaat tgaacgctgg aaaactctga
     1201 acgattttgg cttgcatgct gacaacctga gtacactccc ggctgtgcgc ctgaaaaatc
     1261 tcgcacgtta tgctggtatg acttcggtgt tcaatattgc caggatgtca ccgcagaaaa
     1321 ggatggcggt tctggttgcc tttgtccttg catgggaaac gctggcgctg gatgatgcac
     1381 tggacgttct ggacgccatg ctggccgtta tcatccgtga cgccagaaag attgggcaga
     1441 aaaaacggct ccgctcgctg aaggatctgg ataaatctgc attggcgctc gccagcgcat
     1501 gttcgtacct gctgaaagaa gaaacaccgg acgaatcgat tcgtgctgag gtgttcagct
     1561 acatccccag gcaaaagctg gctgaaatca tcacgcttgt ccgtgaaatt gcccggccct
     1621 cagacgataa ttttcatgaa gaaatggtgg agcagtacgg gcgcgttcgt cgtttcctgc
     1681 cccatctgct gaataccgtt aaattttcat ccgcacctgc cggggttacc actctgaatg
     1741 cctgtgacta cctcagccgg gagttcagct cacggcggca gttttttgac gacgcaccaa
     1801 cggaaattat cagtcggtca tggaaacggc tggtgattaa caaggaaaaa catatcaccc
     1861 gcaggggata cacgctctgc tttctcagta aactgcagga tagtctgagg cggagggatg
     1921 tctacgttac cggcagtaac cggtggggag atccccgagc aagattacta cagggtgctg
     1981 actggcaggc aaaccggatt aaggtttatc gttctctggg acacccgaca gacccgcagg
     2041 aagcaataaa atctctgggt catcagcttg atagtcgtta cagacaggtt gctgcacgtc
     2101 ttggcgaaaa tgaggctgtc gaactcgatg tttctggccc gaagccccgg ttgacaattt
     2161 ctcccctcgc cagtcttgat gagccggaca gtctgaaacg actgagcaaa atgatcagtg
     2221 atctgctccc tccggtggat ttaacggagt tgctgctcga aattaacgcc cataccggat
     2281 ttgctgatga gtttttccat gctagtgaag ccagtgccag agttgatgat ctgcccgtca
     2341 gcatcagcgc cgtgctgatg gctgaagcct gcaatatcgg tctggaacca ctgatcagat
     2401 caaatgttcc tgcactgacc cgacaccggc tgaactggac aaaagcgaac tatctgcggg
     2461 ccgaaactat caccagcgct aatgccagac tggttgattt tcaggcaacg ctgccactgg
     2521 cacagatatg gggtggagga gaagtggcat ctgcagatgg aatgcgcttt gttacgccag
     2581 tcagaacaat caatgccgga ccgaaccgca aatactttgg taataacaga gggatcacct
     2641 ggtacaactt tgtgtccgat cagtattccg gctttcatgg catcgttata ccggggacgc
     2701 tgagggactc tatctttgtg ctggaaggcc ttctggaaca ggagaccggg ctgaatccaa
     2761 ccgaaattat gaccgataca gcaggtgcca gcgaacttgt ctttggcctt ttctggctgc
     2821 tgggatacca gttttctcca cgcctggctg atgccggtgc ttcggttttc tggcgaatgg
     2881 accatgatgc cgactatggc gtgctgaatg atattgccag agggcaatca gatccccgaa
     2941 aaatagtcct tcagtgggac gaaatgatcc ggaccgctgg ctccctgaag ctgggcaaag
     3001 tacaggcttc agtgctggtc cgttcattgc tgaaaagtga acgtccttcc ggactgactc
     3061 aggcaatcat tgaagtgggg cgcatcaaca aaacgctgta tctgcttaat tatattgatg
     3121 atgaagatta ccgccggcgc attctgaccc agcttaatcg gggagaaagc cgccatgccg
     3181 ttgccagagc catctgtcac ggtcaaaaag gtgagataag aaaacgatat accgacggtc
     3241 aggaagatca actgggcgca ctggggctgg tcactaacgc cgtcgtgtta tggaacacta
     3301 tttatatgca ggcagccctg gatcatctcc gggcgcaggg tgaaacactg aatgatgaag
     3361 atatcgcacg cctctccccg ctttgccacg gacatatcaa tatgctcggc cattattcct
     3421 tcacgctggc agaactggtg accaaaggac atctgagacc attaaaagag gcgtcagagg
     3481 tagaaaacgt tgcttaacgt gagttttcgt tccactgagc gtcagacccc tcattcaaaa
     3541 atactcactg atatttttta cactgaaaaa acctaactta ctgtaaaaca aagattcata
     3601 gaatcgccgg taatcgctca atggcgatgg ccatcttcct gattggttgc ggccgttcca
     3661 gattctttga ataagattag gaacctttag ttacaacatt aatgtgtctt gcatgaaaca
     3721 tgctttagcc acagcaactc tactcaaaaa attaagctaa tcaaaaaacg aggagcgcgt
     3781 aagacacaat atggttaaat gcgtgacttt aggagagcat gaaagttgtt acggtgttta
     3841 attccttcct acaaaacaaa cgttccctaa attgcttatg gtagcaatat cgttacgtcc
     3901 ccaatttttc aattattttc taatagcgcc ttttaatttt ttgaaaaata agattttttt
     3961 atattcaata attattcaga aagaaattga cgtgaggagg aataaggttt atatttatac
     4021 tgtatgtata tacagtatca ttgactgatt tttaataaaa aaaggaaatt tttatgagta
     4081 aaaataatca ttcagcagag accgatcatc tttcagtgac tgccgataga cctagtaaag
     4141 gtgatttagg tagtggccca gtaggaaaag gcgatggagg agatagaaat attatcagtt
     4201 taagtgatcc aaatgcttcg ttttcatata ctacgtcaac aatagaaggg cttgagggat
     4261 taaactttac ggtgactgta cacggagcaa ggattattaa tcctcaaaat ggtcatacga
     4321 ctaataatat tgaagttgat ggaaaaggta atagtgttga ttataaaaaa aataatgttc
     4381 agaataacca acttgaatta ccgatacctt ataataataa gttggctcgt gatcgagatt
     4441 tagggagatt aacgtcgaga ataagaaaag attattttga tttgaaaaat aataaggcta
     4501 gagtatctat ttataatggg cattatattc ataccgtcac atttgatgac gctggaaacg
     4561 tgcaaaatat ttctgaggaa tatatagaga aaacctataa tcgctattct aaggggatac
     4621 caaatgagaa aaaagataga ttagaagagg taaagagatt tgcaatatta ggttataaaa
     4681 ctgagcctag taatattctt gattataatg taaaaataaa ggaatatgaa tttattttta
     4741 cattaaataa attaggtttt atagaaaaat tctccaagaa aattataaaa gcatcacaat
     4801 atgaaagccg ccagttaaat gcattctata aagatttaaa tattgaacaa gatgaaaaaa
     4861 aagaaaattt agcgaaatta atggttgtta atgcatatca atcgtaccca caaaataaaa
     4921 aatttatcca agatgcagaa aaagaggcat tgatgggagc ggcagatatt atcactaata
     4981 ctggcgaaaa aattagtaaa cacttggggg aaaaatacaa aactattgct aatgagatcg
     5041 ctagtgattt acgtaacttt cagggaaaga aattacgtag cttgtctgat gcattaaaaa
     5101 tgatggaaaa aatcaaccgt aatcctaata ttaagataaa acaagcggat agagtggtac
     5161 tggctaatgc agtgcgccat gtggatacaa aaatcctgtc tgaaaatttt cagcgtttag
     5221 gtaagtcatt cggggtattg ggtaaagtct tgagtgttga aaagcttcgc gaaaaagcag
     5281 ctattggttt tgagactggt aactggaaac cattgatgct ggaagtggaa gctatgataa
     5341 tcagtggata tgctacgggg atagcgataa gtatagcaat aagttttatc tcatcaattg
     5401 catcattttt agctatagga gcattaccta caaccttagc aattatagca actataatgt
     5461 taattagtta tttagcatcc ttaattgatg ataaagttgt tgataaaatt aacaacttac
     5521 ttattccaga agctcattaa ttacttttgg ttatcttatt tagttaaaac tatctaagat
     5581 aaccatttat ttttataaaa attaagtaat cactatttat caacgaattg atttaaatgg
     5641 aagataaata aatgaaataa aaaaaagaaa caaccaaaca taatatccca aaaaaatagc
     5701 tatatagtaa ccaaataata ggtgtttatt actggatata gttttaagta tactccaacc
     5761 actatctgat atatcagtat tgtaaaaata taaaacatat agagaaataa tcgtaatcac
     5821 aagacatgga aaaataacat ttattattaa tttattaatt ggtataggtt ttacaagagt
     5881 cagtttctta taacaaaaaa tgaaaaataa caatactatt aatggtgata atttgcagta
     5941 aaaaaatgat aacttgctaa ttattggata tgttgatgaa taagttgatg gtatattgtt
     6001 tattttttca tacacagcaa ataatatatc tatatcatta aaataaaaaa taataaatat
     6061 cggaattgca ctaataaaga tgaatattga accccactta attaacaaat gatcatttgg
     6121 gtgattttta ttatccatag taacctgcct ttacgtagta cctatgataa ttaatatatc
     6181 atagttgttt gtaaaacaca taaagaaaca ttaaaacggc tagaatcatt cctctattga
     6241 tatgacaggg aaaaattaat ccctttttat atgaatatat ggatcttgag attgatgtaa
     6301 tactgctaat acttctattc cattctcaac ttctcgatag taaataatat gactttctac
     6361 aggaaaactt cttattcctg taaaaaggtc atcactacga tctataccaa tagagggttg
     6421 tttttcaata atattgatta ttgtgattct taagcaattt atgtaagttt cagctacatt
     6481 ttttccccaa tgggtcaaag aatatcgtct tatggtgcga atatgctctt ttgctttctt
     6541 ggtaaataga acactcattt ataagattaa ccttcaattt cattgctagt taaaggtgca
     6601 aaaacatcat caatatgatg taactctccc cgttctgctt gttcaataga ttcggccaaa
     6661 atagatttta aattttgtaa cttcaactgt gtaaattggt catattcgtc tggagaaatg
     6721 actacagcta cacgctttcc atgtttgctg atctggacag gttcacgttg agctttcatt
     6781 agtaaatcac caaattgatt tttggcgagt tgagcaggaa taatttccat aagtaacact
     6841 ccgtaaaaaa gtacaaaatg gcttgaatgt ctattatagc tatttgttgt gaattttacc
     6901 attaattaat actagtaata aaaaaactgg atcacataag acccattatg ttaaatcgct
     6961 ggctttagtg ataaaaatca ctgttaccct gtcactcata ctctctacct gctaaaacag
     7021 gaagatttct gttattaaaa ccgccaaaat tccattgttt gttttttgtt aaaattgaaa
     7081 caattaagaa acattttaac aaaactattt tttgcatcga aatccctctc aaagccttaa
     7141 aattacaaga aatacgttat taatacattg tatgtacatc accataacag caatgtacat
     7201 acaaagtaaa tacacaataa acacaaaaat gtatttacac aaaaaataca ctgtgataca
     7261 aacatgagca tactctgtac atacgcaatt aatacttaga tgtatttaca atagaagtac
     7321 ataagaagta cagaatggta tttaccacaa caatacaaag aaaatacgag gtatttatga
     7381 ttttagtttt tgcttctgat aaaggcggag taggtaaaac aacaaccgcg atcaatatgg
     7441 ctgttatgct taaaagaaaa aataaaagtg tgattatgct aaaagcagat agaaaccgag
     7501 acttgtttgt ctggtctgat attcgcgcac aagctggctt ctcagcaatt cccattcatg
     7561 aagcattcgg aaatattagt gatgaaataa aacgcctaga aaagctctgt gacgtggttg
     7621 ttgtagactg tgcaggacat gatagctcag aatttcgaag tgcattaacg gtggctgatg
     7681 tattgctcac attggttaag ccttcatcct ctttagaaaa aaacacctta acgaatgtga
     7741 ctaaaaccgt cagaaccgcg caaaagcagc atggtaatag tgacttaaaa gctcacgtac
     7801 tcatgacgag aattaagtcg cataaactgc aagatgccgt atcgcttgag aatgaattaa
     7861 agtccgatga aatttggctg caaccgctta aaaatcgaat ttcagaacta gatatttttg
     7921 aaaatgccgt taacgctggc gtgggtgttc atgaagtaga aaaagcaagt agtttaggtg
     7981 tggcaaaagc gcaaattgaa ttaatcgcaa aagaaatagg gctgatttaa ttcaagggat
     8041 ataccaaatg ccagagaata aatatctata tatcttaatc ctatttattg ctgtggggat
     8101 tatgcttttt gcagacaaat tatttttcta acccgctaaa gtattcatac caagttcgta
     8161 tgaatacttt aattcacaga ctttatacat tgattataaa agaattaata cgctgtacat
     8221 acagctagac atatattaca ctatcattac agcgtacaaa caaggtaaat acaatgaaac
     8281 ttcaaaaacc cgatttagac ttaaccgact ccagcactaa aactaagaac tcgacaaccc
     8341 aattcatcaa ggcgggagac aaacggccaa caacgtcaaa caaacttatc ccatccactt
     8401 ttcgcttgcc agaatccgca attagcattc tcgacaccga agcagaaagg gcagggcaaa
     8461 acaaaaccgc cattttaaaa gccgctatat tggcttacag caaccttgat gaaaacagca
     8521 aaaacttagc attacttgag tcttttaaac tttaaatact ttttttaata tcaacacaaa
     8581 gataattatt atgtatttga ttttttcaat attgctaatg cttggtgcga tatgtgcatt
     8641 atataataca attcgattat tatatttaaa tggtgttagt ggaggattag aggataatat
     8701 ccaattaata ataagtgtaa tcggtattat tgtcatgcct gttttttcat atggttctta
     8761 taaggcatgg agtgaacacc tgacaatatt acaagtattc ggctcataat taaattaatc
     8821 atatgttact ttaatttagt caaaatacat taatgaataa aaatgcaact ggacttgatt
     8881 tttgattatt tagttctgta acaaaagaaa taataatgaa acaattaact gagtttgagt
     8941 tagaaattat tcatgctgtt gtcgttttgc aagaattgca tgataagcca gaactttccg
     9001 ctagtgtatt aaaagaatgt aacctatcgg aaattgattg taacgaatta gatgattatg
     9061 aaaaagataa cttaagaata attaataaag aatatttggt taatctaaaa ggattataac
     9121 aagttactaa ttaataacta gcaaaattaa gggtgacata ttcacccaat tttttacata
     9181 taaaatatta tagttattaa aactcaaaca ctatcagaat aaaacattga tagctcacca
     9241 ttagttaatg tatcttttaa catcgttaaa tgaataacct ttatatcttg attttctaat
     9301 aaattcgatt tttcgatagg attaatgtaa ctaatagcag cgactaattg attctctaat
     9361 gtgtcataaa ttgcaaaagg taaattaata ctattaataa tctcaaattc attaaaaaat
     9421 tcagatgttc ccattttttg agaagaatat aaaaactcac tcaatctcac tttacaaaaa
     9481 acatgatagt tttcttttac attttcttgt aaaataacta ataatttact ttcttcttct
     9541 gtcaaaaatt gctgtctaag ataactcatc tgccctccca agaaccgact gtaggtcaac
     9601 cgcctaacaa aagtaaaatg ctagcatttt tacggttgtt aggctatcct gcatcgcatt
     9661 ataattactt agcctcagat tgtggtgact ttacaccaaa taatgtttga aatggctgta
     9721 tatcttgtaa aacttcgggg ttgataagac tagaaaccat taacgccatt gtcaccgtca
     9781 tttctacatt ccacattttc tcattgttgt aatagaataa tatcaatgca aaaataccga
     9841 gtggaataat caaataacgg aaaacagaga tgatagagac taccatcaat aaaagtacat
     9901 ctagcgttac ccctaagaaa taacgaatcc ccaaaaacag catagaaagt atatgggata
     9961 aggatgattt cttaatatct ttttttatct ttacagatcg agattttttt aatttagcct
    10021 gtatttcttt tttttctttc ccttgaggga attgatatat tttagccata ttaacaccct
    10081 atcttttttc tttacttatt ttatctgcaa ttgtagctac ctttttttga agttttttag
    10141 gtaatttacc attactcaca acctcctcta tcatattttt atttttagct aattgattca
    10201 ttttcttttc gagagactca tcaaaatgac gattagtaaa tgtcacacaa tcattttcgg
    10261 catctaataa aacctcataa tcaggcaaat catttactaa actaagtttt ttaattgaac
    10321 gtttaaactc tcttttgttt gacgtagcgc cagattttaa atgcaataat tctattgata
    10381 atgaaaatga tttttgatat ccacaatgct ttcttgctat ttcataaata cgtcgatcta
    10441 ttgcttttct tatgcgaaaa taatcagaat taatttttaa tactttattt tttgtaatgc
    10501 cctgataaag ccaatcaggt aaagtcactt ctaccatgcc aatatctaat cgtccttttt
    10561 tttcttctaa tattctccat ttatcaatta aaccaaagtt ttctgtttct tgtttttctg
    10621 atgaatatac aatattggtt tgaatacgag taccagctaa acgctcaagg gcttttttta
    10681 attcatcata agaccttccc cctttatcac gattcgtcgt aacaaaaaat tcataaggag
    10741 taaaagcgat agttcgacta atcggttttc cttcaaaaat cgcttgttgc aatttagaaa
    10801 tagcataaat ccaaatatct ttatcaaata cagtagctaa tccaattcca gttgcgggtc
    10861 taactaatac agaaatatta ttatttctgt attctctaac tttatcatcc ccccctttta
    10921 aagcaaaaaa agggtgttcc atactggcta actcatcccg aaaagatgaa atttcaactt
    10981 catcagcgat aaaaaattct tcttccttgt attttttagg tcttaacgtt ttcatctttt
    11041 gtattactta cctttctttt atcgggattc acacacaaat aaattcatac gatgatcacg
    11101 aaatatcggg atttacacac acagtagtta caatatcaac acaaaaaaca tcgggatttg
    11161 cacacaatat atcgggattt acacacgaca gtcaagacta ttttgactaa aaaaaatagg
    11221 aacataatca agagttgatt tactcttgat tatcgggatt tacacacaaa aaacgaaata
    11281 attactgtac aaatttcaaa cagcgattcg ggatttacac acacctcatt cgggatttac
    11341 acacacggac acgggattta cacacacgga cacgggattt acacacacac atctaaaaat
    11401 aattgtttaa attcaatgta ttgtgaggtt tttttttcct taataagttt taataagaat
    11461 taataagtct tttaataaga attatggcaa ttttttgtgg ataactaaca cttcgtctaa
    11521 acatattttg atttgagttt tgggagtatg tgccaacatt aacatcacag atattacgct
    11581 tcctcgatgg aaaataaatt tccatcttgc ggcgagcgtt gcggttttaa cgggttattg
    11641 atctttattt tctccacaag atcatcacta gcagcaatat aatcatcaaa aatgagctgt
    11701 aagccattca gggtggtttt tccccgtata gcctatccat ttaaccaaat ataaatgatc
    11761 gtcgcttaga atcgattaca gcgcgtttga tttaaataaa tcattacatc tcaatcttcc
    11821 cttaaatttc cttgtaatac aataatttag atatattcgc attaaaataa aaagagcaat
    11881 ttttggaaaa aatgcttgat gagtacctta tgaggtacta taatgatttt attgaaagcg
    11941 gaatggttcc ctttcttcca aagccctcac agggcaggag caaaaaatga atgtacaaga
    12001 agcgttaaat atttttggct tatctggtga actcaccgag caagacatca aaaccgctta
    12061 caaaaaagca gcgttaaaat atcatcctga ccgtaatcca ttaggcgcag aactgatgaa
    12121 agccataaat gcagcctttg attttttaat gaataactta gagaacatca ataaatttca
    12181 aagtagcgat aaaaacactc attacaattt taccgaagaa ctggaagagg ttttattaac
    12241 gttgtcgggt ttgatgggga ttatttatga agttattgga aactgggttt ggattagtgg
    12301 agaaaccaaa gagcacaaag acacattaaa agagattggc tgtaaatggg ctgcaaaaaa
    12361 gaaacaatgg ttttaccgtc cagaggaaca taaaagccgt agaaatcgca aagaacacag
    12421 tattgatgaa atacgtacta tgtatggaac aaatggacaa agagcagcga caggctggca
    12481 gagagtagaa aacagggcat aacggatagc gggggtaacc ccgctatttt cataagaaga
    12541 ggatatacta ttatgaaaaa ttttaacgag tgttatcaat ctgtttttga aattgtttgt
    12601 cgttgtctcg gtgataactg gcgcattaac ttacttgata atgatgctta tcggatcaag
    12661 atcacgtcta accgattcat gggcttttca attcatgtta gggaagaaaa aaaccgtttt
    12721 tcgattatgg gtagttttga ttctcgcatt catcgtggag aaattcatag ctgtacggtg
    12781 tcaaaagatc gaaatcctgt acacattgcc gaggatatta aacgaaaaat cattgtattt
    12841 gctcatgatg aaattaataa ggcaaaagaa agtaaagtaa aagaacagga aaaaaaagaa
    12901 caagacttaa ttgtcaaaaa tatgttatct cgtttattta caatgcatag tagctggcag
    12961 agtggggtaa taggtgcatt caagtctgat aatggtttag acggtatgat tagaaaaacg
    13021 tacagtggtt ataaaattga aatagataag ttatccgtag ataatctgat taaactcgca
    13081 ggcatgataa caacgttaga aaggggttaa aaatggaaat taaacgtgaa aatttcgata
    13141 gtgttttcga tattaataaa tggcttaaaa ataacaaaga cgtaaaaatt atcaatattg
    13201 agactagaaa aggcaatata actgatttta caaatagtta tactgtttgg ttttatgtgg
    13261 gttcttattg aggttttatt tttatgatca aactcagtaa aggcagtaaa aactactatc
    13321 tgacacgtga aaacgggcag ttagttttta tcaaaaacat taaggtcaga aataagaatg
    13381 acgttaaaga cggaaataaa acggctaaaa aacaagtgta taaaattatt gttgggattg
    13441 acttgcttcc cgatgaagca gacagatcta ttttaaaaag tatgttggaa caatggaaaa
    13501 gtgaatatga atgaattaaa acgattaaga gataagttag gtctgtcaaa tagtgatctt
    13561 gctgaactta tgggattatc agagcaaacg ataaaaaaca gaatggcatc tgattttaat
    13621 aaaaaaacag caagtaagtt agaaattgaa tttttaaaac tattggcagg tgaacacgaa
    13681 aaatattcaa ttttagaaaa ataaaacttg ataagtacct tatgaggtac tataatgatt
    13741 ttattgaaag cggaatggtt ccctttcttc caaagccctc aaagggtagg agtgaataat
    13801 gaaattgttt catgtgattt taaacgtaac aaatgatgat tttgaaaaaa atattgaatt
    13861 gaaaaatttt tatgaagttg ctcaatcatt aaatgaagta aaagaaaaat ttaaaatttt
    13921 taaaaatgcg cgagttagtg caattgttgt atatgattta ttcttagagc ctgttactgt
    13981 taaatttact atgtctgctt acaatgttca caaccaagtg attttctgtg aatcacaacc
    14041 taccatagtt aataatacgt tagacctgat aacaaaatta aataattact tcaaacaaga
    14101 ttatttaact gtcgattgga aatatattta atgaatacac ctgaatataa aattattagt
    14161 attttcgagt acaacggatt ttacacttac cacatttcaa aaaatggcga gttagatcag
    14221 gttgtcgagt tcgacagtga agcgaacgta acaaaaacat catttaaaca aaattcagag
    14281 gaggaacagg aagccgtaga gtttatacgg agaataagaa ataaacatat ttgttcagtg
    14341 atttaaaggt tgagtctaga gggttgcccc cccctagact ctgacacaaa aaacttacaa
    14401 aggaatttat tatgtcggat aaaatgatag cagcagccaa agattttgca aagggaaaaa
    14461 gaaccacttt tccaatcatg acagtcaaag aattaccttt ttttcttcaa caaatacgta
    14521 aagaaagtga attgttaaaa cattaattta aaatctcaag gggcttaatg cccctttttt
    14581 atgtgcctat ggcacatgtc aggcaaccca ccaaagccaa ttaaaacacc taaatctgat
    14641 ttgccgataa aagggagggc ttttaaatat tctcgaaccc cttccgcact attaagccgt
    14701 gagcgaagcg aaccctataa acacagaata taaagcgact ttagtgttga atggtcgcag
    14761 acaaaaggaa ttcaccgcta tgtttgccgt cttttttctt tttgagatag ataaaaacta
    14821 agctcagagg taagataagt tttagtgcga tgcaggatag cctaacaacc gtaaaaatgc
    14881 tagcatttta cttttgttag gcggttgacc tacagtcggt tcttgggggg taagatgaag
    14941 caaattaatt ttagaattaa tgataatgaa tatgaattat atcataaaaa agtcaaagaa
    15001 aacttaaata tgtcattgcc gagtttttat aaattagtcg gtaatatgat gttaaataag
    15061 gacaaagata ttaaagaaac cttgtctgat catgcgatat cgataggtga agaatctgat
    15121 tataccgata aaagagcata cttgtattta acggctgaac aagaaaatgc gctaataaca
    15181 tcagcaaaaa agcatggttg gtcattatcg agagaaatgc gttttcgtct tcaaacaacc
    15241 ttaagtaatg aaatggattt tttcgaccaa gagttacaag aaatgaaatt atgtcgaaat
    15301 catattaaac gtattggact caatattaat atgatattac gacgtgatga aggacgtgtt
    15361 ttagataaag agggaatgcg tcaagatatg caagcattaa ccgaacagct taatgaactt
    15421 gaaaataaat ttaattactt tatcaataag tgtaaaggta gaattattgc aaatcgattg
    15481 tgaggttggt catgggattg gatatcgaaa aagagtaccg agctaaacgg gctagacaag
    15541 agagtagtcg atcagttaaa tcgattaaat cagctaaatc ctcatttgta cataaagtga
    15601 aaaatggagg gaaattttat gaccgaaacg ctcaagaatc ccgaataaaa aaaggggcga
    15661 gcaaagaggt tatgactaaa ataacaggga gcgcaaaagt taaacaaggg gtaagaaata
    15721 gtgttgatta tattagtcga gatgattcat tagaacttgt tgatgagcag ggtatcaaaa
    15781 tcaatgcgga agaagctaaa caatctttaa ttgatagtga tgatgcattg cagttaagtg
    15841 ataagagcag aagaacacct gatataacta aaaatattgt tttttcaccc cccatgactg
    15901 caaaggtaaa acccgaagaa gcgattgaag ccgttagaca aacgttaata aaaaaatatc
    15961 cagataatcg ttttgtgata gcttatcatg atgataagaa agagcaccct catgttcatg
    16021 ttatattgaa aacacgtaaa gaaaatgaag ataagcgaat caaaattact aaacaggatt
    16081 tgcgtgattt gagatctgga ttttgtgatg aattgaagct caaagggtat gatgtaaaag
    16141 caacacataa acaacaaatt gggttaaagt cacagcttaa agatgattca ttaactgcgc
    16201 ctaagcgcca aaagaatgtt tatgaagtga ttgattttgg gcgagcacct tatcaattca
    16261 atactaaaaa taaatcacaa aattatttga cagtgaaaac cttaaacaag ggcgttgaag
    16321 caacgtattg gggtaaagag tttggtgctt tatgcaatag agaaaaaatt caaaaagggg
    16381 atttaataaa attaaaaaag ataggtacag aagatataaa aatccctaag ctagatgata
    16441 aagggcagca aacagggtgg aaaatcacac agcgtaatca atgggagatg caaaacttag
    16501 gcgttaaagg cgttgatcgc actaaaaata ttttacccga aaattcgggg attaaagaga
    16561 tccaacaatt ccaaaaacaa caaacgcaat ttaaacagca agcaatggaa ttgattaaaa
    16621 aagaacaaca aattaaagtg gggcttaaat tttaatgtta ttcaagagaa ttcgttgtgg
    16681 tggtgcagct tgtatgcatt gccacaacga attgaacaag cggagcgcgt tagtctatct
    16741 atttcctatt ttaagcgttc actggcaaga ttataaacct gacttttttc ccgcttgcca
    16801 acggcaacaa ctgcaataat taacatatcg tcaataactt gatagaccaa tctaaaacct
    16861 gatgcacgaa gtttaatttt atagcaattc ggcatatttc tcagttttgc agatgctaca
    16921 tgtggatttt cacatcgttt tattaattgt ttggcaaatt gagattgaat ggttttatct
    16981 aattttttcc attccttttc tgcatctttt ctaaatttaa ccgaatacat cataggtact
    17041 cggctaaatt aatatcgaca agaggttgtg attctcgttc tttgaccagc tttgcaagtt
    17101 cgttatcgtc tagcgcatca agtatttgct catataactc agcaggaaca cagtaaaaag
    17161 caggttgatt acggtttaaa atggctacgg gatagcctaa acctgcgtta actgtcgcca
    17221 ttgggttttt tttgagttca ctgacgctgg ctgttgtatc acttaaaatc gtatttggca
    17281 taattaaacc ctcaataaga cctattaata ggtcttattt taagattgtt tgctgtgaga
    17341 ttcaatggct agtttgaaaa aaaaatgtaa acacatagta ttttcatagt acatacagat
    17401 ttgtatttac ataatattgc tattgtattt attttggttc gctaatatca gagataacgc
    17461 taaacgtagg gttacaatat aagtacgtaa tagttgttta tttaattata aatatatact
    17521 aatcaatgcg ttaaatgtaa tttgtatttg ttgtttttta ttaaaaatga agaaatatct
    17581 cattcgcttg aaattttatg ttatcaaaaa aatggaacat ttgcttgacc gattagataa
    17641 caagcgttat gtttagttga acaaaagtta tcaagagatt ggagcatgaa cttaaaggaa
    17701 gttaatttgg aagattggca tttagtacat aaagtcactg gtgagtgtat cggtattgat
    17761 atacttaaaa ctcaagatgg tggttctttc aacaaggtat ttttaaatga gcttgcttca
    17821 ataattggtt gcacaggtaa tggaagtgaa aaagttcttg gatggatttt aaaaaataaa
    17881 aataaccaaa atgagattca cggaacgcag cgtgagatag caaaagaaga atctgttggt
    17941 gttgcgactg tagctagggt gtttaaagca cttaaggata acggctatct aaagcaaaaa
    18001 cgatcaggaa cttacttgtt aaatccgtca gttattcatt atggcggagt tggtaacaga
    18061 ttaactatat taagagtttg gaatgattta atttaaatta acgctgtacg taagtattac
    18121 cagtacctac gtacagctaa ccctaaacct acgtcaacta ggagtagagc tatgtcacat
    18181 agtatcttcc atacgcgcat aaatgaagcg caaaataatg ttattgtctt gtttgcttta
    18241 atttcctgca atttgacctc gcgtcagagg ttaaaaatca tcaattctat taatgtaccg
    18301 attgtggtat tgggcttata ttctgctttt tacctgaaaa ggacgtcatt atgaagagtg
    18361 atgaaattat aactttagta gagaaatgcg atatttttga tggtaaaaag ttgagcttta
    18421 agcaaaagga gatagctata cgttatgtgt ttggtcaaac agcagaagaa ttagctatgc
    18481 attttgataa ttctactcgc agtatttggt tacatttgga tgtggtgaga aatgaatttg
    18541 gtaatgtttc tctttcatca ttgagaacaa ttatttttat gaaattaata tgtcagttta
    18601 taaatattaa aatatgatga aagcataatt ttcttatttc taacaataat actaaacttt
    18661 ttagtaagtt aaaaggtaac ttcactttgt gaagttgcct tttttttgta atttaactta
    18721 agatgcaaat catgatttga ttgtgattga tattactgat tggaaattat aaatgaaaaa
    18781 ttcaaaaaca catattacgt tagctgtgcc tgatgattta aatgcatgga ttaattttaa
    18841 atcaaaagat cagaatcgtt ctaaacgtaa ttttctttta catcttattg aagaagcgcg
    18901 cacaaaagat ttgtctaaaa gacaaccgct taatttggat aacgatattt tatgatcaaa
    18961 gaaactttac tttcattagc attgcaatgt gcaccgttag tgcaccctga tactgctcat
    19021 gatattgcta aggttgaaag tggattcaat ccttacgcaa ttgctgaaat aaaagctaaa
    19081 ggtaaagtca ttagccattt acccaaaact aaaaatgaag ccttaaatat tatttcaaga
    19141 ttaaagacga gtaatgctcg gtactcggta ggattaatgc aaatttattc tggtaatttt
    19201 aagggttttg aagttacacc agaagaatta cttgatagct gccgtaactt gaatatcttt
    19261 gaaaaaattt tagttgattg ttatcaaagg ggagggagtc tagccaatgc gctgagttgt
    19321 tattactcag gcaattttaa aacaggaaaa aagaaagaaa cgcagtttgc caacaccagt
    19381 tatatagaac gaataggaat ttcagataat aaaaataatt atattgttcc aagtacaaaa
    19441 aattataagg aagaaaatca ggaggtggcg aaagctgaat cagacgttgt tattgagaaa
    19501 ttaaaaccat caaacaaaat tgtttatcct cgttatgtaa tgaggggtgt agtcaaagaa
    19561 aattagggat ttaatatgaa aacatcacaa aaattgccat ttctattaat gtgcggatta
    19621 atgtcattga ttgcttttac ttttcctgct caagctgctg atgtaactac agcgacaaca
    19681 ggattcttag ataggatcat tgatttttta acgacaatta gaaagccagc tatcactatt
    19741 tgtgctctag gtattggttt tattgcatta tttgcgcgta atcatatggc ttggatatat
    19801 ccactgatta tcgggattat tatctttatc attgcgccat atctgcctga ttggttgggt
    19861 taatttaaat atttatcgta tttaaattaa ctatacgttt aacctctcta tcaaggggct
    19921 gttatgagca ctgtttttaa gggactaaca cgccccgcac ttattcgcgg gttaggcgtc
    19981 ccattatacc cgtttttatt tacttgtgtt ttgtgtgtgt tacttggcgt ttggatacat
    20041 gaagcacttt attttttaat tattgtcggg atatttgtta ttcgaaaaat aatgaagatt
    20101 gatgaacggt attttgaatt aatttatctt cgttatttag tgatgggaaa tcctgtttca
    20161 aatcaaaaat atcatgctgt tcatgtaggt gggaatgatt atgaccgtgt tgatttatcc
    20221 gatgtggaga attttatgaa acttagtgat caggcttcat tggaaaaact cattccatac
    20281 tcttctcata ttacggatga tttagtttta agccagaata gagatttaat tgctacattt
    20341 gaattatcgg gggcttactt tgaatgtgtc agtgaaaatg atttgtcatt aatggttgat
    20401 cagcttaata cactcatacg aagttatgaa ggcaaacccg taactttcta tacacatcgt
    20461 attagaaata aaaaacaggt taaagctgag tttaatagtc ctattccttt tgctaatcgc
    20521 gtgatgaatg cttactacgg ttcattaaca aaatctgatt tttatcaaaa tcgtttattt
    20581 ttaaccgttt gttttaagcc tttttcatta gaagaaaaag tggctcaatt tttaagttct
    20641 aaaaagaaaa ataaacaaaa agataaatcg attttagctg aacccattaa cgaaatgaat
    20701 gaaatctgtg ctcgattaac taactattta tctcgttaca aagcacatcg tttaggggtt
    20761 tatactgaga atgaccgtgt attttcatct caattgagtt tttatcaata tctgcttagt
    20821 ggacagtggc agccagttag agtgacgaat agcccgttct atacgtattt aggtggtaaa
    20881 gatattttct ttggtggtga tgcggggcaa attagtattt ctgaaccgat gcgctatttc
    20941 cgcattatcg agatcaaaga ttattttcaa gatacagaat ctggtatttt tgattcgttg
    21001 atgtatatgc ctgttgaata cacattgaca acctctttta cgccattaga caaacgggaa
    21061 gcaattcaaa aactcgatga ccagcgtgaa aaattagaaa tgacggacga tgccgctaaa
    21121 tctcaaatta ccgatttaga ggttgctgtt gatatggtct ctagtggtta tttatcgatg
    21181 ggtcatagcc atttaacgct gtgtgttttt gctgatagtc ctgatgaatt ggttaaaaac
    21241 acgaatatgg taacgggggc gttacaagac ttagggctta ttttgagtta ttccacttta
    21301 tctttgggag ctgcgttctt ctctcaatta ccagggaatt atactttgcg tcctcgatta
    21361 tcgattttga gtagcctgaa ttacgctgaa atggaatgtt tccataattt ctttacaggg
    21421 aaagaaacgg gaaatacatg gggtaattgc ttattaacct taaaaggttc tggtaatgat
    21481 atctatcatt tgaattatca catgacgacc gaatatcaga atttttttgg taaaaacccg
    21541 acgctagggc atagcgaaat attaggtaca tcgaatgcgg gtaaaacggt gttaatgatg
    21601 atgcaagcct gtgccttaca acaatttggg tctgaaactt cttttccacc gaatagtaaa
    21661 gttaaaaaac aaacgactat cttttttgat aaagaccgcg caggggaagt cgctattcgt
    21721 gcgatggggg gcgattatta taaagtgaaa ttgggtgaac caacaggttg gaatccattt
    21781 gctatgcctg cgactaagcg gaacctgatt tttctaaaag atttaattcg taatttatgt
    21841 acgttaaata gcgaaaaagg gttaaccgaa tatcaaaata aactgatttc ggatgcggta
    21901 gaacgattaa tgcagcgaga agatcgctct ttcggtatca gtaagctgat cccacttatc
    21961 atggaggaaa gaacagaaga aacattacga gatggactca aaatacgttt agctgcatgg
    22021 aaacaaggtg gtgaatttgg ttgggtgttt gataatgcca cagatgattt tgatatcagc
    22081 gataaaacca tttttggcat tgatggcacc gaatttttag aagatgccat tttatctcag
    22141 gttgtgcctt tttatctgat ttacaaaata acgttattag cagatggacg tcgtttaaca
    22201 ctgtattttg atgagttttg gcagtggtta gcaaacatgc tgacagccat gatgatttat
    22261 aacaagctca aaacagggcg aaaactcaat atggtcattg tttttgccac tcagtctcct
    22321 gatgagttat tgaaatctcc aatgatttca gccctgagag agcaattagc aacacatatt
    22381 tacttagcta acccgaatgc gaaaaagagt gaatatgttg atgggctaca agttaatgaa
    22441 ttgtatttta ataaaatcaa aaaaattgac ccgctttcaa gacgcttttt agtggttaaa
    22501 aacccacaac gaaaaggcga ctctcaagat ttcgcggcat ttgccagtct tgaacttggg
    22561 gaagctgcat attacttgcc gatattgagt gcatcaacag agcagttaga aatatttgat
    22621 gaaatctacc aagacggtat gaaacctgat gagtggatag atatctatct tgaaagagca
    22681 aaccaagccg cttaggagat aacaatgaac aaattcaaat taacattgat cagtatggta
    22741 tttggggctt catttatggc ttcggctggt attcctgttg ctattgacgc taaccctgaa
    22801 tgggcgattg aagcggggcg gtggtctgaa aaattgaagc aatggtccga tacagtgaaa
    22861 cattataatg ctcaaattca gtcctatcag gatgaattgt tagctaagac gggtatccgt
    22921 gatgttcagc aattaattca agatgctcaa tccatcaaaa atgatttaac ggcaatttac
    22981 aatcaaggga atgcgtttat tgacaaatac gcgcaaaacc caacggaagc gttctcacag
    23041 caagctcaag ccctgttatc taaatataac gtttcaaaaa cctgtgcgaa caaaggctat
    23101 gtgggggatg caattaaagg gtgtgaagcg cagtttttat caattctttc tgtgtcagag
    23161 tacggtgatt cattgcaaaa gcaattagag caagataata gccgtatgga aagcctgata
    23221 aagcaagtcc aaaatgcgaa agaccctaaa gcgacggctg atgccgcaaa tgcgatttct
    23281 tttgaacaat taaaatttga aaaattacag ttccagtatc aaatgtaccg agacaaacag
    23341 cgtgatttag ctgaatataa agaacagctt aatcaagcta atttccgtga taagcagcta
    23401 aaagcagtag atagtcaacc ttcatattta gatgcttatc ataagtctca atttgatgag
    23461 gaatttcagt aatgaaaaca aaattattaa ttggcgcagt atctattctc tttctatcgg
    23521 catgtggtga agaagtgaaa tcagttcaat ggtggcaaga acatgcagat gaagcacaga
    23581 aaaaagtaac ggaatgttct tccaacggaa atgatagtga aaattgccga aatgcaaaag
    23641 atggattatt ccgtcataaa caattaacag caaaatcacc atcttttatg gatgcatata
    23701 agaaaacaca aaacaaagaa taggtaaatt atggaaaacg cgacagctac atccgacttt
    23761 tttcaaacag catatcaagt tatttgggat atgctgaata aaacagtggc aaataaggtt
    23821 tctgaatact ctcaaattgc tgcggatttg gcacagtacg ggatttcaat ttatatttta
    23881 tggtttgcat tcagtacgct agctttaaaa aataaaacgc ctgtgcctga ttttatttgg
    23941 aacttggcgc gttttactat catcttgatg tttattaaaa atagcggggg ctggctgagt
    24001 gccagcaccg atgctattta cggattgcgc gacactttgg caggtggtga tccttggaag
    24061 tggatggatc aactgtgggt taaaacatct caggttgctg cacatataat gtcaaaggat
    24121 acatcaacgt atgtgaaagt tgatggggga attggctcat ttcttactta ttttggaggg
    24181 ttggctgctt tacttacttg ctcattcgta ttttttgctg ctgaaattac tttattactg
    24241 ctgacgacaa cggctcctat tttcattttg tgtctgatgt ttggtttttt acggcaaatg
    24301 ttcaataact ggttacaact gattttcagt tctttattca ttgttatgtt tggttcgtta
    24361 gcgttacggg cgggtatgtc gtttttgaat attgttttga gcgtttcggt ggctcaagct
    24421 gcggaagcta atctcatgca attaggggca actgcggcag cggctggatt atttatggta
    24481 tttgtaatga ttttagctaa aaactttgca actcaactag caggggtagg tgtagacggt
    24541 gcagttcagg gtatggcaat gatgggagtt gcaggagctg ctgtaatggc atttaaaggt
    24601 atcagaaaag caggaaatac cgcgtcaaat atgggtaaaa gtaatcgaga taggggctgg
    24661 aatggggctt cagcgagtgg gaatagtggt tcgtctgcgc ctaactcggc aaaatcgcgt
    24721 cggcaagcct cgattgataa tgtgagaaaa cgttatggaa cataaaatga aaaaatatct
    24781 aatacttgtt gtttttcttt taactgcctg tcaatcaaat aaattactcc ccaaagtcac
    24841 tggtgagttg caacccataa atacggcaga ggtgatgaaa aatgaaaaat aaaccaagag
    24901 gggcttacct tagttataaa taatttaatc gtgagttttt aaatggagtc atttatgagt
    24961 ggcattatta tcgctgtaat ttttttcgtc atcggatttt ttgtatctgt cgtaataaat
    25021 attatagttt caggctctga aaaagagaaa ataaaaaatt ttattactat ctataaagaa
    25081 tatgacgtga aaatcacaga ttcctcatgt cggctttctt gtgataaagg ttatatcgaa
    25141 gtggaaacca aaaattattt gagttttatt caaaggggag gtagatatga aaaataaaaa
    25201 agtgggaata ccatttttaa aaaagaaaga aaaaattgaa ctagcaaaaa ccttcgaaga
    25261 aaaagacatt aaaaaacaaa aaatcattaa tacgttgtat aagatttttg ggctttctgg
    25321 tttggcgttt gcttttttaa gtttacttgg ttggataatg atgctgccat taaaaaatac
    25381 ggaagtggaa atatggacag ttgacaaaaa tacagggaaa acagaaaagg tgtcacgtgt
    25441 gaaagatgaa aacctgacaa aagatgaagc gttaggtcgc tattttgtga cgcaatacat
    25501 taaagcgcgt gaagggtata actattttcg tttacagcat gattatgaca tggtgatgtt
    25561 atggagtgcg gaaaatgtcg ctaatgatta taccgctatt tttaaaacgg atgctagacc
    25621 aactattgtg tataaaaaag cacaacgtac cgttgatata gaaattatct atcctgtttt
    25681 tattaatcca tcgtctcaga aaggtgatcc tgatttgtta gctaccgttc gttttaaaaa
    25741 aatcatcaag gatgtcacaa caaatcgcag tgttgaggaa acatgggtag cgagaatgac
    25801 ttaccgtttt atgcctgacg ttgagaaaaa agaaagtgaa cgaaatgcaa atccattagg
    25861 ctttgttgta accagttggg tcgctgaaaa agaaattcga ggttaataat gaaaaagaaa
    25921 agtcttttgt tattactggc tgttttttta tcacaacaaa gtactgcgga aatattacct
    25981 tctgcaagtc gctatgaccc acgaaatcaa gttgttaatt tcaatccgtt aaatacgacc
    26041 gtgattaata gtgctattgg ctatattaca acggttgtgt ttgatgatga tgaaaaggtg
    26101 attgatgcac aaacaggcta tgagcaaggt tgggatattt ctaaagcaga taaccgcgtt
    26161 tatatccgtg tgttacctgt aaaacaagtt gttgaagaaa tggcggacaa tggaaaggtt
    26221 gagcaaaaag aaattgcgct tgaccctgaa acagacttgt cacgctggca aacaaattta
    26281 tttgttgtga ctacaaaaag aaattacagc ttagaattga atgcgaaaac atttaaagag
    26341 ccaaaaaaaa tagcctttgt ggtgaattat cgttatcccg atgaaaaaag aaaacagcaa
    26401 aatgaaattg aacaacaacg tttagctgaa taccaacggc aacaagaaac cgcaaaaatc
    26461 aatcgggaac ttgaaaatgc caaaacacct aaaaattggc aatattatca acgagtggct
    26521 aaaggtagtg aaatgattat gcctgactat gcctatgatg atggtcgatt tacgtatttt
    26581 ggatttaatc cgaataaaaa aatgccgagc ttattttcac aaattgggga gcaagaaacg
    26641 atcacaaacc caacaattga aaaacggggg aattatacgg tattagtcgc acatcaagtt
    26701 aatgaccgtt ggattttacg tttaggggat caagttattg gtattgaaaa taaaggactt
    26761 ggtaaagtgc gtttaagtaa cagtgatact gtttctgaca atgttgttaa agaggtgatc
    26821 caatgagtga agatactgaa aagccattaa ctgccgttga aattgagcaa aaacttaaac
    26881 aagaacgtca attgcaaatt gaccaatctt ccgaaaataa agaatcaacg ccagaaccaa
    26941 aaaaagtttc acttgggatt gataaattaa aaaaatccaa aaaaggaacc gtgttgctta
    27001 ttcttttttt tgtcttatcg attggtgcat tgtctttata ttatttccct tcgttattgc
    27061 gtgcgtttat tagcagtgat gaagcggaag aagtgccaca agaaacgatt tcaaccggtg
    27121 gccgtgacaa gttaacaggg ctaaataatg atgttgaccc atttggtcaa gcagaattaa
    27181 acaatgcagg tgagttaacg acggcaaata ccaatgagcc agctgaaagt acaccaccac
    27241 cgccaaagcg cattgaattc agtcgtggaa tggacagagg ggtttcgaca cgctcaagca
    27301 gtactagcac acctagtagt agccaaaatg cacccgtaga gactgtgagc gcaacaacga
    27361 cgcagcctga aacggttgtt ggcagtaaaa ccaaaataac gcgcttaccc tatgacccga
    27421 atttgtttat tcctgaaaat acggcaattc cgtgttcgtt agatcgtcga tttgtctcag
    27481 atttagcggg taaattgacg tgtaccgtct atgaggacgt ttacagtgca aacggcaatg
    27541 taaagctaat agataaaggc acggtagcac atttggttta taagtcggct tatgtgccta
    27601 atcaggggca agggcatgtc tttttaatgg caactaagct acgaacccgt acacagcctt
    27661 ttattgatat tccattagta gattccgaag ctgcgggcgc attaggtgaa acgggggttg
    27721 atggttggat tgatacgcat ttttgggatc gcttcggtgg ggcaatgatg ctaggcatga
    27781 tccccgatgc catgcaggga ttaaataatg tggcaaaaga taataaagat aatcagaccg
    27841 attataccgc gaatagtcgt caagcctttt ccgagatagc aaaacaggca tttgcgaaca
    27901 gcgttaacat tccgcctacg ctgtataaaa atcaaggcga aattatcacc ttgattacgg
    27961 gaagtgattt agattttagt tcaatttacc aattaaggat gaaatagtta tgcgtgaata
    28021 tcacaatcaa catctcattc acgatttaac gcaacaattt tttgctgaat accttaatgg
    28081 cgttaaggga ttaacggaaa ttgcggtaaa tgagcctaat aaactctttt tgaaggttaa
    28141 aggacgttgg gagaaacgcg aaccgaaaat atcatatgat gattgtcttt cttttgcgtc
    28201 aacgttagcg gattatcaca gtgattcaat cggtgatatt aagcctgttt tatccgcaac
    28261 actgcctcac ggtgaacgtg tacaggtggt tattccccct gcgtgtgaaa aagataaagt
    28321 ctctattacg atccgaaaac cctcgaatgt gtttattacc catgatgata ttgtgaagtc
    28381 aggattttat tcccgagtgg ggcagtcatt taaatcagaa aatgcttcat ctgatttagt
    28441 ggatttatac cacacgggta attttgcagc gtttattcct gaatgtttac gtcaagggaa
    28501 aaccatggtg ttttgtggcg gaacggggag cggtaaaacc acgtttagta atgcggttat
    28561 gttttatatt ccacatcatt tacgattaat ttctattgaa gatactgacg aaacccgttt
    28621 tcgttttcat gaaaatcacg tcaaacttta ttatccgtca gaggggggaa ataaccttat
    28681 cacctcagca tcgttactcc gtgcatgttt aaggatgaat cccgaccgta ttttaatgac
    28741 agaaattcgg ggtgcagaaa cgtgggattt tttaaaggcg tcaagttcag ggcattcagg
    28801 tggtgtaact acggtgcatg aagaaaaacc agaagatgcc attttaggca tggtgacacg
    28861 gtgttatcaa aatacggagt gtaataattt accctttaat gcattagtcc gaaaagtgtt
    28921 aaataacatc gatgtcatca tgagcattaa ataccttagt gatgatgata agcgttttgc
    28981 gagtgatatt tattttaaag atgtccatca aaatgattac ttagcgagac tgttagggta
    29041 ggaggaataa tggcgcgaaa atatcccgac aaacctcaaa gtatttttat tgctattgtt
    29101 atgttaggta tcacatatta cgcaggaagt gtgattgttt attttttaaa tggttatgat
    29161 tttttatata tttataagca ttatcaatct gatttattgt ggcaattgat tagcgaaagc
    29221 cgaattaaag catctatacg ggtaacggct attcctgctt tgctgattgg cttcgtggca
    29281 tcttttattt tacctgtggc ggtgatttat ttattaaatc aagaaaaaat gtcacttcac
    29341 ggagatgcaa aatttgccag tgataatgat ttaaaaaaat caaaactatt aaaatgggaa
    29401 aaggaaaatt caaaaggtat tttagttggg aaatataaag ggaaatacct ttggtatacc
    29461 gcgcctgatt ttgtgtcatt aggggctgga acaagggcgg gtaaaggagc agctattggc
    29521 attcctaatt tgcttgtgtg gttgcattcg ctgattattc tcgatcctaa acaagagtgc
    29581 tggaaaatta ccagtaaagt ccgtgaaaaa ctgttagggc atcgggttta tctggttgac
    29641 ccgtttaata gcaaaacaca cgggtttaat ccctttttct atatcgaatt agataaagaa
    29701 agtggcgcaa aagatttatt aaagttagtg gaaattttat ttccatccta tggctcaaca
    29761 ggggcagagg cacactttaa taacttggca ggacaatatt ttacgggatt aacaaagtta
    29821 ttatatttct ttattcatca tgcccctgaa tatttgaaaa cgtttgatgt taaacctgtt
    29881 ttttctattg gcagtgtcgt ggatttatac gggcgtattg atagggaatt agtccttaac
    29941 aacaggcaag aaattgaagc caaagcccgt gatgaaaata cactttatca tttacaagat
    30001 gggctaacaa aactacagga ataccattta accgaagatg aacagcgttc gagtgtcgat
    30061 ggttcatttc gaaaaaaaat gagtctgttt tatttaccca cagtacgtaa atgtacagat
    30121 aataacgatt ttgatttacg tcagttacga cgcgaaaaaa tcacgattta tgttgggatt
    30181 aatgcggagg atttaggtat tgcctatgat tttttaaatc tcttttttaa ttttgtggtt
    30241 gaagtgacat tacgtgaaaa ccctgatttt gacccatcat taaaacattc atgcttgttg
    30301 atgttagatg aatttccgtc aatcggttat atgccgatca ttaaaaaggg ttctggctat
    30361 atcgcaggat ttaacttgaa attgttaacc atttatcaaa atgttagcca gttaaatgag
    30421 atttacggca tcgagggagc gaaaacattg ttaagcgccc atccttgtag ggttatttat
    30481 gctgtcagtg aacaagatga tgctgaacaa atctcggcaa aacttggtta tatcacgaca
    30541 aaatcaaaag gagaaagcaa aagtcaaggt cgtggttcat ctaaaagtaa atcggaaagc
    30601 gaagcacgtc gtgctttagt tttaccgcag gaattaggta cgctcgattt taaagaagag
    30661 tttattttat taaaaggcga aaaccctgtt aaagcagaaa aagcgcttta tttttctgat
    30721 aattatttta tggacagatt gttaaaggtc agtccgaaac ttgaagatga agtaaaaaaa
    30781 attaataaga aatcaacggt tattggggtg aaaggattac gttatcccga taaagaaaaa
    30841 atgctgtcat taggtgaatt agaatctgag gtgtttttat gaaaaaagga ttatggctta
    30901 gtgttgtttt attaacggca tgttcatctc cgccagaagc cccgaaagtg gattggggaa
    30961 aaaaagaggt tgcggtaaat gctaaaataa tgacatggac accaactcat accgtggtga
    31021 gtagtgacgt cgttaatgat gaatggcaaa aacgaattaa taattttatt cctgaaaatc
    31081 gtctttatga tgatgcggtt tattttgcca ttgcacattc gaataaaatt attgttgaag
    31141 caaataatgg cactgaattt ttgaaaacaa aagaatggtt acaggctcac ggtgcaaatg
    31201 gggtaataca atatcaaaaa aaatcaaact ggttaaataa tccaataaca gtttatctta
    31261 ttaaggaaaa tcaaaatgaa aagtaaaatc gttgcgataa gtttattttt cttacccgta
    31321 ttatcacaag cagatgtccc cgtattcaca ggggatgtca agttagcttg tgaagcggtc
    31381 ttgtgtcttt catcaggtac gcgcccaagt gagtgcgctc ctgcattatc acgttacttt
    31441 ggtattaata aaaagttttg gtctgatact gttaatgcaa gaaaaaattt cttacagctt
    31501 tgccctgcat caagtgatgc aggaatgcct gagttagtta atgccattgc taatggcgca
    31561 gggcgttgtg atgctactta tcttaataaa tttctgtatg aagaaaagag agagcaaaag
    31621 tgccgcagtc ggggaaagga agaagattgt tggtatgaaa cgtactatcg cataaaaaat
    31681 gaacttccta actattgccg tgcttacgtt aatcatgaat ggactgattt agatagtagc
    31741 ctgcattatc agggaaaaat ggaatgggtt aagaaagaat ctgtggcagg ttggaataat
    31801 tcaggtggtc gatgggttga ttagcctata taggggtatt ggcataaagc tgtaccccat
    31861 taaaaaatgg aggttgttat gaatgcgata aaatctattt atggaaagat tttattttta
    31921 ccttgcattt ttatttattg tttttatgta tgtttttctg tgttggcgga tgtgacaaaa
    31981 ataagttatc agtatttaac aaaagaaatt aaacgatttt aattaaaggg tgactttatg
    32041 aagaaactaa aaaaatagga tggagtgctg ctaaggaaat ttatagcctt gctgtttttg
    32101 ttattaagct attactcatt ttagcaatta ctattccgat tattattata tggctgtata
    32161 tcattctaac ttttgatggt tctcagattg atgaaatttc attcagccaa tttgttgcga
    32221 gtggcaacgt acaatatttt tcatttatta tttctgtttg tgtgtatgcg atttatcgtt
    32281 ttttggattt taataataga aaaatcaaaa aggaaaatag agtttatttc aactataccg
    32341 atgatgacgc tgaaaaaata ctgaaaagta aaaatgcctt ttatcctgat gatgaattgt
    32401 tttcatggat tgatgaaggt gaactcgtcg ttgaacaata tatgtcaaaa gaccaagttg
    32461 gacggttagt gaaacagtac atgatagaaa ccaacggaat gccactgaaa attgtttttc
    32521 ctgaatatga caaaggaagc gaccaatgaa atatttagat cttgatcctt tcgcctatgg
    32581 tgataacccc gaagaagcaa acaaattaat ggagttggaa tttcgggagt tgtttgattt
    32641 tatatcgaaa caactaaaag aagaaagact aattcatatt ttacaagaaa atataggtat
    32701 gaatgaacaa ttgtctattc atacctattg caaaaaaaga caaaatcatt atttgcctga
    32761 tgatattgat ttacattacc tcgttaatgg aaatgtactt tccaaagaag atgaagataa
    32821 gattattgaa aaagtattta agtatcgagg tggggtttat gtttggaaaa gcaatgcaaa
    32881 aataaataaa taaaatggga gtggataatg attaaacaaa ataaaatatt aacacttcat
    32941 gagttattta aattttgtga agcgaacggt gtttttcgat tagtcaaagt cgaagaaaac
    33001 gactcatttg ttaaaattat tatctgtggc gtttatcaaa ttaggcttaa taaaaaaaca
    33061 caaaaagtca cattgcatac gtggtttttt acaaacttag agtcaggcga gtggcgagtt
    33121 agaaaatcat tacctaaccg aatcccttgt ttttggaaaa atgaaaatat atataatata
    33181 caatattggt tacaaagtgc agtaacccat gttattgact caatagtgaa atcaaattac
    33241 tcgatcagtg gtatatgtta tatgtataaa tcattttatg gagggattga aacgaaaata
    33301 cttcttgaag atatacaacc agattttgat acgactagtg aaatgtttga ggaaaaaacc
    33361 tttttttatc ctcattattt agcgggtatg agtatgagta aaatgcgtca tgatatttgc
    33421 ataaaaatta tgactagaat aaatgcattt attaataatg aaacccaaaa atatgcaagc
    33481 atgagtttat ccaaaaatat atggaaagtt attgataagg gggtattttc tttatacgga
    33541 aaagcacatt ttaattcctt cgtacgtaat tcaatattag atgctaattt tttggattat
    33601 tataaattct caaaacagat acgcatcaat gataatgtcg attataaagg actttggttg
    33661 atgataggtt ttttacggaa gcaaaaaaaa tctaattatc actatacttt aacaggtaaa
    33721 ataaaagacc tgtataaaga gctacaacta cctgaatcaa tttcttacgg ggattttaaa
    33781 tatatgtata cattaaagcc ctcattaatc gcacagttaa ttgaatttat aagtctacgt
    33841 gacagatatc ggtttggtat aaatgataaa attaaaataa tcatgaaatt actcaggcag
    33901 cctgaaatta aaaaataccc tactaaggct atttttgatt ttttagagac cgtatggaat
    33961 ggtttacgcg ttgaacatgg ttatacttcg gtttaccgca ttgcattaaa atggctcgat
    34021 tatcatcaag acctttataa aaatattggt tataaatcgg taacaagacg ctggaacacg
    34081 gaactaaatc gctttgcaca tgctatagaa tgggtgttta acaccgattt ttacatccaa
    34141 aaaaatcagt ctttagcttc tatctatcga ttatcagaag aatgggttga agaactcaat
    34201 catgacgatt atgactatgc agaaatttcc cctcaatgga atggtattga tattgattgg
    34261 caatcgtgca tttctgaaat gacggtaagt gaaattacga cactagaaca actaaaaaaa
    34321 gaaggtcaag aaatgcatca ttgcgtttat tcctacgctc atgattgcgc caatgaaaca
    34381 tatcgagttt tcactatcat aaataatgat gaaagagcca ctttagggat ttcacaagtc
    34441 gaaaaccata aaatattcaa atttgaccaa gtaatgggag tatcaaactc tgcggtttca
    34501 agtgaaataa taaaaatgag taaaaaagta ttaaaccaag tcaacagcaa aataaataaa
    34561 gttaatttaa ttaatttagg agagtaaatt atgagagtct ttattgcgga aaaaccatca
    34621 ttagcaaaag ccatttttga gggattaggt ggtaatccaa acacggaaaa gaaaaaaggg
    34681 tattttcaac acggtgacga tgttgtgacg tggtgtgttg gtcacatgct cgagttgagc
    34741 gacccccaag attatgatga gaaatatgca agctggcgtt ttggtgactt accgattaaa
    34801 acggttttcc caccaaccta taaaataaaa aaagaaacgg cagcacaaac aaaaatcatt
    34861 ttgtcattaa ttgaccaagc aaaaaccatt gttaatgctg gcgacccaga cgaggaaggc
    34921 tgtcttctgg tcaatgaaat tttagattac gcaaaaaata aaaagcccgt agagcgtatt
    34981 ttagtatcgg atttaaactt agcacctgtt aaaaaagcct tagccgattt acaaccgaat
    35041 gaaaaatttc gcggtatgtc aaacagtgcg ttatcccgtt ctctgctcga tcagagtttt
    35101 ggctataacc ttactcgtgg ctgtacatta aaagggcgtg aaaaaggcta tcaaggtgtt
    35161 ttaaacgtgg gacgggtgca aagtgcagtt ttggggcttg tgaatatgcg aacattggcg
    35221 aaccaaaacc acaatgaaag tttctattat gatatttatg ctttaattga gatgaacgga
    35281 catcaagtta aggcgaaata tcaaacaacc gataacgatc agattgatga taagcgtcgc
    35341 ttaatctcag aagcccaagc caaacacatt actgaaatcg tttcagggca agcggtaaaa
    35401 gtgaccattg cagcaacgaa agcggaaaac acaaaaccac ctttaccgtt aaatttatct
    35461 acactacagc aaatttgcgc taaacgattt ggctatgccc cacaagaaac gctggatatt
    35521 atgcaaagcc tgtatgaaac gcataaatta ttgacctatc caagaacaga caatcgttat
    35581 ttgtctgacg agcactatta ccaagcgaat gatatcgctc aagcagttat cggtacattg
    35641 ccagaattgg caagcacggt tgagcacatg gataaagttc aaaaacacaa agcctttaac
    35701 gccagcaaaa ttgaagcgca tcatgctatt gtgccaacaa cgaaagacgg ctctaatatt
    35761 caattgaatg agaaagagaa aaatgtgtat cgattagttt cactttactt tattggctta
    35821 ttttatcccg atagcattcg agataaaaca aaagtgcatt ttgatatcaa aggcaacacc
    35881 tttaccgcca cacaaagcgt attagtccag tcaggatggg aatcattagg taaagacagc
    35941 gacgaagaag aaacagaaga gccagaaaaa ctcgactttg atttatcaac gttaaaattt
    36001 aatgataatg gggtgtgtga aacagctaac gtggataaaa agcccactct tccacctaaa
    36061 tattttactg cttcaacact cctttccgct atgacacgtg cggcaaaatt tattgatgat
    36121 cctgaacttc gaaaaatact tgaagctaaa gacgagggga gcactgatca aggcagtatt
    36181 ggcacagaag cgactcgcgc agggatatta aaaaaactct ccgaaaatac gggattaatt
    36241 tcgattgaaa aagaaaaagg ctattcagag cttgtttgga aaacaacaaa gcaagggcaa
    36301 gagttttgcg ctgctctgcc tgatgaaatt accaagcccg atatttcggc tcgatgggct
    36361 gaaaaacaag ccttaattaa aaaaggggaa ctgaccgttg ctgactttat taaagaaaca
    36421 gacagctata ttaaggagtt gattgccgaa ctcgacgcta acggaataaa tatcacagct
    36481 aacggtacac cttgccctgt ttgtcaaaag gggtttttaa tcaaacgtaa ggggcaaaat
    36541 ggtttctttt ggggttgttc atgctatcct gaatgtaaga cggcatttcc cgataaaaat
    36601 gggcaaccag ttacagaaaa acaacctaat gagggcgcag tagcacgttt aaatgtcatg
    36661 tgtccgtcat gcagtaacga aataattatt cgaccaaaag gatacttctg tacaggatgt
    36721 gaatttaaaa tatgggctga attttgcagt aaaaaactca cacagaatca agtggaaaaa
    36781 ctcattaaag atggaaaaac tgccgttatt aaagggttta aaaccaaagc agggaaaaca
    36841 tttgatactg aacttgtttt agatgataag aaaacaggga agataggttt ccctgaaaag
    36901 aaaaagtaac tattattttt taacagaaaa ccatttttat attgaggtaa aacatgagcg
    36961 aattaactag agaagaaaaa tacaaaatta cgtctgaatc actgacggga ttaacagagc
    37021 taagaaagtt tgcaaaaacg aaaaattttg aatggttaga aaatcttgcc aatcaactca
    37081 atggtattgt agaagaacag cgtgaagaat tcgagttacg caaacttgaa cttgctgaac
    37141 tggaagaaaa acgcctaaaa gcgattaaat acttagaaga gttggggtta gatccagaaa
    37201 caatccacat ttccgttttt gaaacaaccg ataaaaaagg aaagaaaaga aagtctaaaa
    37261 atacgcctgc gaaatatcgc tttacgcatc ccgaaacagg taaaacagac acatggacgg
    37321 gaattggtcg tatgaagaaa ggattgcaac tattaattga tgcaggtcat tctctcgatg
    37381 aatttttgat tgataaagcc agcgatgcta aagatgacat taaagaagcg gaaaaactct
    37441 ttgaaaatca cccttcttcg ttgggttaat ctccctctcc tgctgtctct tacattgcct
    37501 gttatcgggc aatgtaagcc cctttttatt ggtgattcac tgacttatga actcgccatg
    37561 agttacaaaa aaattgcccc tgttgatgct aaattccttg aaagcacagg gttgcaatca
    37621 aaacagattt taagttggca agattacaca cagaatatcg atttttcgct ttatgacacg
    37681 gtgtatattg ttttaggtac aaacgatctc atttctaagg cagatatccc cgaataccaa
    37741 caaaaagcta gtgtctttat ccaaaccata aaaaagcaaa ataggcagat tgtttggtta
    37801 ctccccccta ccctaaaaaa taaagaaaaa aataatttat tatcaaatac ccgaattgca
    37861 atctgtgaag cagcaagaaa aaataagata aaaacgatgg atactcgagt atctttaggg
    37921 tatcaatact cagagtttat taatggtgtt aaagtaagaa ccagtgatgg tattcatata
    37981 acagaaaatg gggctgataa tgtaataagg agcttaatta atgttgataa agaaaataac
    38041 agatagcatt attgcattta tatataagac aacggataat tatgtcattg atcagttaaa
    38101 tgatgttaat ttaggtaaag ttgagctata taaacccacg gcggattcaa atactatttt
    38161 gagataggat gagcttttta agaattatat ggttaggggt tttcctacag aaattaaaga
    38221 tataattact aatttgtgcc gtatcgagaa aactatagac tatttttttg attttaataa
    38281 aatacaatca ttaacagcat ctaaaagttt tggtggcatt cctgatggcg ctataaacgg
    38341 tagctggttt tatgatttgt atagttgggg gcgcgcaatg tatcccgacg aaagaatgaa
    38401 agcggaaaat gaagatgatt ggaaacgaaa tattgcgcac attgaatctg aggggttcag
    38461 aaagtgcaga cctattaatg tcatatatta cgaatggtta aataggtttg ttgcccctaa
    38521 tacaggcggt tctcatcatg ccgcattggt agtgtatcaa tcaatcagag ataaaattaa
    38581 atacacaaga gaaactattt tagaaaaggt ttctcttaat agttattata tacgaatgct
    38641 ggataatgaa tactattctt tcatcattaa taatgatagc aatcccaaat ccctatcgga
    38701 aagtgataaa tttattaatg taataacaga gctaatcagt acgcatattt caattctgaa
    38761 acccgtacat tattatcaga acttaatgat tatctttatt cctaaagaat cattaaaaat
    38821 agattcagaa ttatttaata actggattaa taaagcacat gaccagaaaa aaataatcaa
    38881 tctgccgaac tattttagat taccaaatga atatcataca aaaccttatt tgcatgaact
    38941 tcgttatctg aaaatgccaa atccaaattc tatttttcaa tagaaagggt gcttgaaacc
    39001 taaactaaac acagaaaaag aaaatgcggg ggaatgctcc cccgctaggc atcaccgttc
    39061 ttcgtaagaa agtgttgcct gaactactgt attcccacta ttcacactga tagaacagag
    39121 tctatcgcgc attaacagag agaaacacag taccgttaaa caaacggcaa tcagccctat
    39181 cagggcgtac ttggtcattt tccttgactc ctaacttatt aggaggcaca atttctagtg
    39241 ctaagtagag aattgcagcc tcgattatgg taataaataa ccttatcggg gctttcttct
    39301 atctggctct cactaaatgc ttgaaccgga caggatcaag cacccgctga aagattacca
    39361 aaagttgaac aaaacagcac gcaattagca ctatgacgct ccataactga ttaatctggt
    39421 gcatttacgt gaaatttgac cactaatccc cctgccatta cgctaaaatt cacgtaatac
    39481 aacgtctttt tgtctcattg gggtctgacg ctcagtggaa cgaaaactca cgttaaggga
    39541 ttttggtcat gagattatca aaaaggatct tcacctagat ccttttaaat taaaaatgaa
    39601 gttttaaatc aatctaaagt atatatgagt aaacttggtc tgacagttac caatgcttaa
    39661 tcagtgaggc acctatctca gcgatctgtc tatttcgttc atccatagtt gcctgactcc
    39721 ccgtcgtgta gataactacg atacgggagg gcttaccatc tggccccagt gctgcaatga
    39781 taccgcgaga tccacgctca ccggctccag atttatcagc aataaaccag ccagccggaa
    39841 gggccgagcg cagaagtggt cctgcaactt tatccgcctc catccagtct attaattgtt
    39901 gccgggaagc tagagtaagt agttcgccag ttaatagttt gcgcaacgtt gttgccattg
    39961 ctgcaggcat cgtggtgtca cgctcgtcgt ttggtatggc ttcattcagc tccggttccc
    40021 aacgatcaag gcgggttaca tgatccccca tgttgtgcaa aaaagcggtt agctccttcg
    40081 gtcctccgat cgttgtcaga agtaagttgg ccgcagtgtt atcactcatg gttatggcag
    40141 cactgcataa ttctcttact gtcatgccat ccgtaagatg cttttctgtg actggtgagt
    40201 actcaaccaa gtcattctga gaatagtgta tgcggcgacc gagttgctct tgcccggcgt
    40261 caacacggga taataccgca ccacatagca gaactttaaa agtgctcatc attggaaaac
    40321 gttcttcggg gcgaaaactc tcaaggatct taccgctgtt gagatccagc tcgatgtaac
    40381 ccactcgtgc acccaactga tcttcagcat cttttacttt caccagcgtt tctgggtgag
    40441 caaaaacagg aaggcaaaat gccgcaaaaa agggaataag ggcgacacgg aaatgttgaa
    40501 tactcatact cttccttttt caatattatt gaagcattta tcagggttat tgtctcatga
    40561 gcggatacat atttgaatgt atttagaaaa ataaacaaat aggggttccg cgcacatttc
    40621 cccgaaaagt gccacctgac gtctaagaaa ccattattat catgacatta acctataaaa
    40681 ataggcgtat cacgaggccc tttcgtcttc aagaatttta taaaccgtgg agcgggcaat
    40741 actgagctga tgagcaattt ccgttgcacc agtgcccttc tgatgaagcg tcagcacgac
    40801 gttcctgtcc acggtacgcc tgcggccaaa tttgattcct ttcagctttg cttcctgtcg
    40861 gccctcattc gtgcgctcta ggatcctccg gcgttcagct tgtgccacag ccgacagg
//
