LOCUS       NZ_CP070146             6220 bp    DNA     circular CON 05-JAN-2024
DEFINITION  Klebsiella oxytoca strain FDAARGOS_1331 plasmid unnamed2, complete
            sequence.
ACCESSION   NZ_CP070146
VERSION     NZ_CP070146.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN16357473
            Assembly: GCF_016904515.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella oxytoca
  ORGANISM  Klebsiella oxytoca
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 6220)
  AUTHORS   Sokurenko,E., Tallon,L., Sadzewicz,L., Zhao,X., Boylan,J., Ott,S.,
            Bowen,H., Vavikolanu,K., Mehta,A., Aluvathingal,J., Nadendla,S.,
            Yan,Y. and Sichtig,H.
  TITLE     FDA dAtabase for Regulatory Grade micrObial Sequences (FDA-ARGOS):
            Supporting development and validation of Infectious Disease Dx tests
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6220)
  AUTHORS   Sokurenko,E., Tallon,L., Sadzewicz,L., Zhao,X., Boylan,J., Ott,S.,
            Bowen,H., Vavikolanu,K., Mehta,A., Aluvathingal,J., Nadendla,S.,
            Yan,Y. and Sichtig,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-FEB-2021) Institute for Genome Sciences, University of
            Maryland School of Medicine, BioPark II, 801 W. Baltimore St., Suite
            619, Baltimore, MD 21201, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT v. 8.0.0, HGAP v. 4
            Genome Coverage                   :: 904.14x
            Sequencing Technology             :: Pacbio; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/05/2024 07:44:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,691
            CDSs (total)                      :: 5,575
            Genes (coding)                    :: 5,481
            CDSs (with protein)               :: 5,481
            Genes (RNA)                       :: 116
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 6
            Pseudo Genes (total)              :: 94
            CDSs (without protein)            :: 94
            Pseudo Genes (ambiguous residues) :: 0 of 94
            Pseudo Genes (frameshifted)       :: 37 of 94
            Pseudo Genes (incomplete)         :: 55 of 94
            Pseudo Genes (internal stop)      :: 23 of 94
            Pseudo Genes (multiple problems)  :: 18 of 94
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP070146.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..6220
                     /organism="Klebsiella oxytoca"
                     /mol_type="genomic DNA"
                     /strain="FDAARGOS_1331"
                     /host="Homo sapiens"
                     /culture_collection="FDA:FDAARGOS_1331"
                     /db_xref="taxon:571"
                     /plasmid="unnamed2"
                     /geo_loc_name="USA: WA"
                     /collected_by="ARMADA"
     gene            362..1117
                     /locus_tag="I6K61_RS28270"
                     /old_locus_tag="I6K61_28275"
     CDS             362..1117
                     /locus_tag="I6K61_RS28270"
                     /old_locus_tag="I6K61_28275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001555316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_094955594.1"
                     /translation="MGIEDSNKGPGWHDHDTPYGTIHSYDGNTSTYNGGGGSGGAAGSG
                     FTGLTANTWVDVSTTKDYNGRYMSMCLNNLKDHEGSINTMYRDSKGNITIGIGHYLGSA
                     QMAQALPFSRTKVVRLHGDDMESEVAVSKSDIAAAYNAYKKNPKEQQSIHLSNADVIGQ
                     CIKDVQTTETGLRSLYPGYNDFSDPRKTALVDMGFNLGVPTLKEVFVNFNDAVNRGDWN
                     TAADESHRTLNQRGDKRNKDTYDQLRYNR"
                     /name="hypothetical protein"
     gene            1223..1741
                     /locus_tag="I6K61_RS28275"
                     /old_locus_tag="I6K61_28280"
     CDS             1223..1741
                     /locus_tag="I6K61_RS28275"
                     /old_locus_tag="I6K61_28280"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_128335106.1"
                     /translation="MIRFLSFCFCFCFLFLFCVGEASADVKVYFAPKSTVYETDTSAEI
                     RKYLESFGKGGGGYENDNPKAVIEAMIKYQNKIQKKVSGFFNGNDMIKYDGAVCKISIT
                     TGNTAPSDPILTQVFALEQLADNGLKPCRELNNKLVSVIDKDDNFKYPAVVKNYGLLSM
                     DMIFYFNNN"
                     /name="hypothetical protein"
     gene            1773..1907
                     /locus_tag="I6K61_RS28280"
                     /old_locus_tag="I6K61_28285"
     CDS             1773..1907
                     /locus_tag="I6K61_RS28280"
                     /old_locus_tag="I6K61_28285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724569.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_071891505.1"
                     /translation="MRCRIILLFVAVALLVSCQANYIRDVQGGSVAPSTSSTISGASS"
                     /name="colicin release lysis protein"
     gene            2648..2839
                     /locus_tag="I6K61_RS28285"
                     /old_locus_tag="I6K61_28290"
     CDS             2648..2839
                     /locus_tag="I6K61_RS28285"
                     /old_locus_tag="I6K61_28290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_044347887.1"
                     /translation="MTKQQKTALNMAKFIQNQSLLLLEKLNELDLDAEADLCEKLHDDA
                     EHLFRTLSSRLDALQDDN"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            2839..3240
                     /locus_tag="I6K61_RS28290"
                     /old_locus_tag="I6K61_28295"
     CDS             2839..3240
                     /locus_tag="I6K61_RS28290"
                     /old_locus_tag="I6K61_28295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009310048.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_044347889.1"
                     /translation="MARVSISEAARLTGKSRTTLHRLIKTGELSTCNGERNAKMVDTSE
                     LLRVFGPFEQPKGEHHSGQVSEQRDTAPADQSEQVIRHLKQEVEHLNTLLLSKDSHIDS
                     LKQAMLLLENHQAKLTDAPAPWWKFWKKS"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(3780..4217)
                     /gene="tolA"
                     /locus_tag="I6K61_RS28295"
                     /old_locus_tag="I6K61_28300"
     CDS             complement(3780..4217)
                     /gene="tolA"
                     /locus_tag="I6K61_RS28295"
                     /old_locus_tag="I6K61_28300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001567367.1"
                     /GO_component="GO:0098567 - periplasmic side of plasma
                     membrane [Evidence IEA]"
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein TolA"
                     /protein_id="WP_044347900.1"
                     /translation="MHIRPLPALLLVLPLLMTACNGSHTLKMDARATPANTKPAEVDDL
                     LGDLQSTTVIPEQSRISTYARQVQKAIAAQMNEPNAYAGKNCVINISLQPDGSVNDATA
                     KEGDERLCKAAISAITRAKIPAAPDEKTYQMLKNATIDFRL"
                     /name="tolA"
     gene            complement(4299..4703)
                     /locus_tag="I6K61_RS28300"
                     /old_locus_tag="I6K61_28305"
     CDS             complement(4299..4703)
                     /locus_tag="I6K61_RS28300"
                     /old_locus_tag="I6K61_28305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013811315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /protein_id="WP_044347891.1"
                     /translation="MMCIRPLTLILPLLLTACSGSQTSVERNASHAASAIERMHFDPNT
                     RMQRADSITALKPMMQQLYDQGKKDRTDGLTPAQAQKRVESFSCPDVLSGGQKTRILGK
                     EYDADNPEKQRQILLEAGISSYWDGYNGRS"
                     /name="Exc2 family lipoprotein"
     gene            complement(4886..5185)
                     /locus_tag="I6K61_RS28305"
                     /old_locus_tag="I6K61_28310"
     CDS             complement(4886..5185)
                     /locus_tag="I6K61_RS28305"
                     /old_locus_tag="I6K61_28310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009365129.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_044347893.1"
                     /translation="MPYDVEWKQGAIEDVTTLFGYIAENSSLWDARNVTERILAAADKL
                     SDYPRLYEVDSRYGDDVRRLSLMGQHVLYEVDDQARKVRVLAVVGQRQNPHLVR"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(5175..5438)
                     /locus_tag="I6K61_RS28310"
                     /old_locus_tag="I6K61_28315"
     CDS             complement(5175..5438)
                     /locus_tag="I6K61_RS28310"
                     /old_locus_tag="I6K61_28315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_044347895.1"
                     /translation="MSNTSHYENANFLRELAESLPRILPAGGADKAALLQRLANEELAQ
                     AEYEEQVRAKVTAARADTRPGMTTEQLRQRLHGRYREVRDAV"
                     /name="hypothetical protein"
     Typing          complement(2123..2600)
                     /name="ColRNAI_rep_cluster_1987"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="90.476"
                     /coverage="92.0"
                     /evalue="5.84e-177"
ORIGIN
        1 gcagctgcgc gtttctggcg ggttttcggg tggtttattg cccattttac aggtttcccg
       61 tcagaaacgc cctgaggccg ttttagcggt gcgcataatc agggctttat gttaaatggc
      121 cggcgtaaaa aagccccgaa gggcttttac cgcgtatcaa ctaagttgaa ccatgggctg
      181 atttataaaa aataaaaaat agtcaatttt atttataaag aatgggttta ataaaacttt
      241 gcttatttta aaataaacta aagacctgtt attgacaggg tgggtgataa tatgtaacct
      301 cagcactgta tgtttataca gttgtttttt tattaatcta tacgtcagag aggtaattta
      361 agtgggtatt gaagattcta ataaaggtcc aggttggcat gatcatgata ctccttacgg
      421 gactatccat agctatgatg gtaatactag tacttataat ggtggtggtg gttcaggcgg
      481 ggctgcagga agtggtttta ccgggttaac agctaataca tgggttgatg tttcaacaac
      541 aaaggattac aacggtcggt acatgtccat gtgtttaaat aacttgaagg accacgaagg
      601 ttctatcaat accatgtata gagatagcaa ggggaacatc accatcggta ttggacatta
      661 tcttggatct gctcaaatgg ctcaagcatt gccatttagc cgaactaaag ttgttcgttt
      721 acatggtgat gatatggaaa gtgaggttgc agtatctaaa agtgatatag ctgccgcata
      781 taacgcttat aagaaaaacc caaaagaaca gcagagtatt cacctttcga atgcagatgt
      841 aatcggtcag tgtattaaag atgttcaaac tacagagact ggattacgca gcctttaccc
      901 tggttataat gatttctctg atccacgaaa aaccgcatta gtagacatgg gattcaacct
      961 tggtgtacca acgcttaagg aagtcttcgt taattttaat gatgcggtaa atcgtggtga
     1021 ttggaataca gcagctgatg agagccatag aaccctaaat caaaggggtg ataaaaggaa
     1081 taaagatact tacgatcagt tgcggtataa tcgatagtag tataaatttg ttgctcctat
     1141 ctattaggat gggagcaagt cataagtaat tttttaagct tatagactat gatgaattta
     1201 atgtcttcta tgaggttaag ttatgatacg ttttttgtct ttttgttttt gtttttgttt
     1261 tttattttta ttttgtgttg gtgaagcatc tgctgatgtt aaggtttatt ttgctccgaa
     1321 atctacggtg tatgaaactg atacgtcagc tgagattagg aagtatttag agagttttgg
     1381 taaggggggg gggggatatg aaaacgacaa ccctaaagct gtaattgaag ccatgataaa
     1441 atatcaaaat aaaattcaga agaaggtttc tgggtttttt aatggtaatg atatgattaa
     1501 atatgatggg gctgtttgta aaatatcaat aacaactggg aataccgctc catcagatcc
     1561 tatattaact caggtgtttg cgcttgaaca gttggctgat aatggtctga aaccttgtcg
     1621 tgagcttaat aataagttgg tgtcagtaat tgacaaggat gataatttta aatacccagc
     1681 ggtggttaag aattatgggt tgttatctat ggatatgata ttttatttta ataataatta
     1741 actttctttg ctgctaattt tggtggtttc ttatgcgttg ccgaattatt ttattatttg
     1801 ttgcagtggc attgttagta tcatgccagg caaactatat cagggatgtt caaggcgggt
     1861 ctgtggcgcc ctcaacgtct tctacgataa gtggtgctag ttcttagtaa aggatcttct
     1921 tgtgatcctt tattgatcat cgtaatctct tgctctgtaa acgaaaaaac cacccggcaa
     1981 ggtggttttc tcgaaggagc agaaaccggc aagtttctga accgaggtaa ctggctttcg
     2041 cagagcacag aaaccaaatt cgttttatca gtgtagcctt tgttagcctc actcatcaag
     2101 acttctttgc tctgcgaacc tgttaccagt ggctgctgcc agtggcgctt ttgcatgtct
     2161 taccgggttg gactcaagac gatagttacc ggataaggcg cagcagtcgg actgaacggg
     2221 gggttcgtgc acacagtcca gcttggagcg aactgccttc ccggaactga gtgtcaggcg
     2281 tggaatgaga taaacgcggc cataacagcg gaatgacacc ggtaaaccga aaggcaggaa
     2341 caggagagcg cacgagggag ccaccgggtg gaaacgcctg gtatctttaa agtcctgtcg
     2401 ggtttcgcca ccactgattt gagcgtctgt ttctgtgatg cttgtcaggg gggcggagcc
     2461 tatggaaaaa cggcaacggc gtggcctttg tttgctttcc gcggctattg gctctgttgc
     2521 tttgtgttct tacgcatgag cctctaccgc tcgccgcagc cgaacggcag gagcgtagcg
     2581 actgagtgag cgaggaagcg gaaaagagac cggttttaca ctgagcactg acgctctgag
     2641 gccctttatg acgaaacaac agaaaacggc gctgaacatg gctaagttca tccagaatca
     2701 gtccctgctc ctgctggaga agcttaacga gcttgatctt gatgctgagg ctgacctttg
     2761 tgagaaactc catgatgatg ctgagcatct tttccgtaca ctgtcctcga gactggatgc
     2821 attacaggat gataactgat ggcccgagtg tctattagtg aggctgcccg gctaacgggt
     2881 aagagccgga caacactgca caggttaatt aaaacaggtg aactgtccac ttgtaacggt
     2941 gaaagaaatg caaaaatggt cgatacctca gagcttttac gcgtttttgg cccctttgag
     3001 caaccgaagg gcgaacacca ttctggacag gtctctgaac agcgtgatac agcccctgct
     3061 gaccagagtg aacaggtcat tcgtcaccta aaacaggagg ttgaacacct gaacaccttg
     3121 cttttatcca aggattcgca cattgacagc ctgaaacagg cgatgctcct tcttgaaaac
     3181 caccaggcaa aattaactga cgctccggcg ccgtggtgga aattctggaa aaaatcctga
     3241 tcgcgtcatg cttccgtttt gctctccggc cattccgggg agttcctgaa ccttcccaaa
     3301 aattgccaga tctctgaacg ctcctcacaa cgaaaaatac ccacacccca cgcaaaatta
     3361 aaattttgct gatttctatt taaaatcaat taattaatag tttgaaattt cgttttttaa
     3421 attttattta catagatcag actctatgac gagtcgtcat agagtccccg gggagtcgtc
     3481 atagagtcgg taatgactca gtactataaa atcagagagt taacatcgaa ccgactctag
     3541 acacgactcc ccgtttggtt gatttgtgac catggcgact ctaggcacga ctctagagta
     3601 gagtcgcggg tgaatcgtgt ggtaagtcgt ccggtgactt gccattcgtc agtgccggct
     3661 gttatgaact ggattcctga aggtgctgaa acctgttttc cggctgcgcc ggcaacgttt
     3721 cgcggccacg caataaattg cgtccccgtt caccgctttt gaaattacgg tggctgtttc
     3781 tatagtctga aatcgatagt tgcgtttttg agcatctgat aagtcttttc atcgggtgca
     3841 gcaggtattt ttgctcgtgt aatagctgaa atagcagctt tgcagagcct ttcgtcaccc
     3901 tcttttgctg ttgcatcatt cactgagcca tcaggctgaa gagagatatt gatcacgcaa
     3961 ttttttcctg catatgcgtt tggttcgttc atctgcgcag ctatggcctt ttgtacctgg
     4021 cgtgcgtatg tacttattct ggattgttcc ggaatcactg tagtggattg aagatcacct
     4081 aaaagatcgt caacttccgc tggttttgtg ttggcaggtg tggcacgggc atccatcttt
     4141 aaggtgtgac tgccattaca tgctgtcata agaagtggaa gaacgagtaa gagagctggt
     4201 agtggtctga tgtgcatgag catatttctc tgttcatccc tgatgaggta caggaaaccc
     4261 cttttatggc gtttcccggc ataattattt tcgatgaact aagaacgccc attatagccg
     4321 tcccagtatg aagatattcc tgcttccagg agaatttgac gctgcttttc ggggttatca
     4381 gcatcgtact ctttgccaag gatccgcgtt ttctgtccac cggacaggac gtcagggcag
     4441 ctgaagcttt ccacccgctt ctgagcctga gcaggcgtta gaccatcggt tctgtctttt
     4501 ttcccctggt cgtagagttg ctgcatcatg ggtttcaggg ctgtgatact gtcggccctt
     4561 tgcatgcggg tattagggtc gaaatgcatg cgctcaatag cggatgcagc atggctggca
     4621 tttcgttcaa cgctggtctg tgagccggag caggcggtca gcagcaatgg aagaatgaga
     4681 gtgagtggcc tgatacacat catggagctt ccctgtctgt ttaaattaac cccatgatag
     4741 atgcagttaa tggagttcgt aaacagttga aaacatcaca cgactggact taaacctggt
     4801 tgaacagggg ggaagtggag gatacgtcga cgcgcttgcc taatagtgac gggcaagtaa
     4861 taaattgcac actgtgacag gttactcagc gcactaaatg cggattctgc cgttgtccca
     4921 caacggctag aacccggact ttcctggcct gatcatcaac ctcatagaga acatgctgtc
     4981 ccatcagact gagccggcga acgtcatcgc catatcgcga gtccacttcg taaagtctgg
     5041 ggtaatcgga gagcttgtct gctgcagcga ggatacgctc cgtgacgttt cgggcatccc
     5101 acagcgatga attttccgcg atatagccaa acagtgttgt aacgtcctcg atagccccct
     5161 gtttccattc cacgtcatac ggcatcgcgg acttcccgat aacggccatg cagccgctgg
     5221 cggagttgtt cggtggtcat acccgggcgt gtgtcagcgc gagcagcggt gactttggca
     5281 cgaacctgtt cctcatactc cgcctgggcc agttcctcat tagccagacg ttgcagcagt
     5341 gcggctttat ctgcaccacc ggcgggcagt atccgaggca ggctttcggc cagttcccgc
     5401 agaaagtttg cattttcgta gtgtgaggta ttactcatgg ggaagcctcc ctgtgtttat
     5461 gcgtgtgtgt gaaggagtgt agcaggggga agaccggaaa aatatggtta agctcgctcc
     5521 tgattgctgg tgcgtattct gtcccaatgt gaacgcagtt tctcagttct gctgtcggta
     5581 accgttcatc ttcgccagaa tacgcacatg attcaatttt tctctccgcc cattccaggg
     5641 agttcctgaa ccttcccaaa aatcgccaga tctctaaacg ctcctcacca ctaaaaatac
     5701 ccacacacta cgcaaaatta aaattttgct gatagccatt taatttcaat tggttatcta
     5761 ttttaaatta cgtgaactta ccttctgtaa ggtgaatcca attcgttgat gactctatgg
     5821 tgaatcgctg acgaattacc cacgattcat atgtgaatca cgctttatta tcatattgtt
     5881 atgatgaatt gactcttgat tcaattcatc attttggatg ttttttgttc atggtgattc
     5941 ttgattcaat tcacgattcg aatcgccggt gaatcgtgtg gtaagtcgtc cggcgacttg
     6001 ccataacgtc attgccggct gtcgacgaac ccgattcctg aaggtgctga aaacctgttt
     6061 ttcggctgcg ccggcaacgc ttcacgggga cgcaataaat tgcgtccccg ttcaccgttt
     6121 tcggaggtga agaacgtcgg aaacagacgt caccctggct aaacgaactg aatttccgcg
     6181 ctatgcactt gctcgcatac tcatgcatga cgtaaaaaca
//
