LOCUS       NZ_CP069966            27282 bp    DNA     linear   CON 03-DEC-2023
DEFINITION  Klebsiella pneumoniae strain FDAARGOS_1307 plasmid unnamed4.
ACCESSION   NZ_CP069966
VERSION     NZ_CP069966.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN16357449
            Assembly: GCF_016903775.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 27282)
  AUTHORS   Sokurenko,E., Tallon,L., Sadzewicz,L., Zhao,X., Boylan,J., Ott,S.,
            Bowen,H., Vavikolanu,K., Mehta,A., Aluvathingal,J., Nadendla,S.,
            Yan,Y. and Sichtig,H.
  TITLE     FDA dAtabase for Regulatory Grade micrObial Sequences (FDA-ARGOS):
            Supporting development and validation of Infectious Disease Dx tests
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 27282)
  AUTHORS   Sokurenko,E., Tallon,L., Sadzewicz,L., Zhao,X., Boylan,J., Ott,S.,
            Bowen,H., Vavikolanu,K., Mehta,A., Aluvathingal,J., Nadendla,S.,
            Yan,Y. and Sichtig,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-FEB-2021) Institute for Genome Sciences, University of
            Maryland School of Medicine, BioPark II, 801 W. Baltimore St., Suite
            619, Baltimore, MD 21201, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT v. 8.0.0, HGAP v. 4
            Genome Coverage                   :: 981.01x
            Sequencing Technology             :: Pacbio; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 12/03/2023 03:32:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,565
            CDSs (total)                      :: 5,442
            Genes (coding)                    :: 5,308
            CDSs (with protein)               :: 5,308
            Genes (RNA)                       :: 123
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 12
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 63 of 134
            Pseudo Genes (incomplete)         :: 72 of 134
            Pseudo Genes (internal stop)      :: 27 of 134
            Pseudo Genes (multiple problems)  :: 26 of 134
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP069966.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..27282
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="FDAARGOS_1307"
                     /host="Homo sapiens"
                     /culture_collection="FDA:FDAARGOS_1307"
                     /db_xref="taxon:573"
                     /plasmid="unnamed4"
                     /geo_loc_name="USA: WA"
                     /collected_by="ARMADA"
     gene            complement(<1..1695)
                     /locus_tag="I6K37_RS27485"
                     /old_locus_tag="I6K37_27480"
     CDS             complement(<1..1695)
                     /locus_tag="I6K37_RS27485"
                     /old_locus_tag="I6K37_27480"
                     /EC_number="5.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247728.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /protein_id="WP_204746008.1"
                     /translation="MKLFIAEKPAVANDIVKALGGNFTRHDGWFESDNTIVTNCFGHII
                     ESQPPENYNPEYKEWKIETLPLRLYPVKYQPVESAEKQVKTIIELIRRADVTEIIHAGD
                     PDDEGQLLVDEVLEYAGNTKPVKRVLINDNTLPAVKKALANPKNNRDFRGLYLKALARS
                     VADAIYGLSMTRAYTIPARAKGYKGTLSVGRVQTPILGLIVNRTRANKNHKSSFYYTMT
                     GHFQRGVDVIRANWKPGEFAPLTDRKLLDKAWANGTAASLAGKPATVEAAATDDKKTAA
                     PLPFNLVRLQQYMNKKFKMTAQQTLDITQQLREKYKAITYNRSDCSYLSDEQFSEAPQV
                     LDALKSVFDQPLDVDSTRKSKAFNSAKVTAHTAIIPTVNVPDVNALSSDERNVYLAIAQ
                     HYLVQFMPEKTYQEVSVAIQCGDESFYARARKTTDSGFEAFLGEENTGDEESEAENDDS
                     AFDLLCKIRTGETVTTKEVVVNEKKTTPPPLFTEATLLAALVRVADFVTDPVIKKLLKD
                     KDRDKKDEHGGIGTSATRASMLETLKKRNYITLEKGKLIPTDTGYALI"
                     /name="DNA topoisomerase"
     gene            complement(1700..2275)
                     /locus_tag="I6K37_RS27490"
                     /old_locus_tag="I6K37_27485"
     CDS             complement(1700..2275)
                     /locus_tag="I6K37_RS27490"
                     /old_locus_tag="I6K37_27485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001358168.1"
                     /translation="MQYALLDGFERKFLLDALEFGVLKDWKENPVKELPDIDESAHPFH
                     VCYGGYLLNPGVSDSDIIRKIKDQTGFWLAAIDDTRMDCHSIAYYDIHTLPLISCGHQK
                     IVPFAALIKADECIISKISSYSGFAVTAFLRIKDQDIATNILNREGIFAFNGCERRFRH
                     PVSEDNWQQAVSEERAIRCAKRLIQCKG"
                     /name="hypothetical protein"
     gene            complement(2445..4121)
                     /locus_tag="I6K37_RS27495"
                     /old_locus_tag="I6K37_27490"
     CDS             complement(2445..4121)
                     /locus_tag="I6K37_RS27495"
                     /old_locus_tag="I6K37_27490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001708409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfJ domain-containing protein"
                     /protein_id="WP_000289345.1"
                     /translation="MYVINQQTRDNNILTLHDVFKIYQNTGGLRLVKTEENEKYISIII
                     CGVFRIRKNKKNNKITLWGYKLRDKHTGVWTRRNSFPGKIFLFWSKKSAYDMDDWLKYA
                     ISYIIKSLIEAGYSIEDKLYLLRIGEEEENSESRYISTLYPSNVYYSYEYGIHDIVHCL
                     GKIASFNYPYNTRYISRHILLAEIKNKIYQRALKIIGMDNEFNASKALSKAIWIMVDKK
                     IFAQYARASHCSIAYNSIRQALFEDYLDFSKRIHIVNDMDFFGLWPMVGRLRQQHKNGQ
                     FILSGKTKELYEKISFPCKLSYGEFRSLRHVSLSLVYALNDKHDNASFRFTVRLLRHPL
                     IKNYPVRAIYWIIDYISIRAYPEKENDIYRICSKWLEYHRDLFKNIGFYDRNTESRQTS
                     RWEMETNQLCHAIDWLLAEERLIHKNQEWPSFWRLSDEWTRQVKNNVIPVIPKWKGTGI
                     NWQKVDNGVNELITFDALCQEGQEMEHCVASYADWCASGEYIAISVLMDNERATLGLSR
                     KEHDLTYQFDQMRGIRNQAVSRNMLIKGRHILKIINSSLKR"
                     /name="PcfJ domain-containing protein"
     gene            complement(4216..4748)
                     /locus_tag="I6K37_RS27500"
                     /old_locus_tag="I6K37_27495"
                     /pseudo=""
     CDS             complement(4216..4748)
                     /locus_tag="I6K37_RS27500"
                     /old_locus_tag="I6K37_27495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001542050.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /name="thermonuclease family protein"
     gene            complement(4778..5431)
                     /locus_tag="I6K37_RS27505"
                     /old_locus_tag="I6K37_27500"
     CDS             complement(4778..5431)
                     /locus_tag="I6K37_RS27505"
                     /old_locus_tag="I6K37_27500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000572553.1"
                     /translation="MIEQLQSDFLFWIFIYFLIVGLLIRNIHLTRKIKSIEKNKMFPAE
                     EYAVLDIEQHMSNKYIGRLVTRFMKRTNGAPLLIVFPEYDKGDNNEDKNSPPFQLVKLT
                     SNINNIKEIYSNDDLNCFLNNISAQKNLYTTHSGPSQAWIEHAYPLQQVTILLQGTRHS
                     EREDIISQLEIILSRLKNGENTGFEHDDDFGYSFQYDAAAVGKSSFFDEAAGRK"
                     /name="hypothetical protein"
     gene            complement(5443..6567)
                     /locus_tag="I6K37_RS27510"
                     /old_locus_tag="I6K37_27505"
     CDS             complement(5443..6567)
                     /locus_tag="I6K37_RS27510"
                     /old_locus_tag="I6K37_27505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000486721.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA];
                     GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="WP_000486714.1"
                     /translation="MFQKIKIRKMTISRALDKYLKTVSIHKKGHLQEFYRVNVIKRHPI
                     AERYMDDITTVDIANYRDQRLAQINPRTGRQITGNTVRLELALLSSLFNIARVEWGTCR
                     MNPVELVRKPKISSGRDRRLTSGEERRLSRYFKEKNQALYVIFHLALETAMRQGEILSL
                     RWEHVDLQHGVAHLPTTKNGAPRDVPLSRKARNYLQMLPTQLNGNIFSYTSSGFKSAWR
                     TALHELKIENLHFHDLRHEAISRFFELGTLNVIEVAAISGHRSLNMLKRYTHLRAYQLV
                     SKLDARRKQTSKIAPYFVPYPATVENRNGQVVVTLSDFDLETSAATKEQAIFHASVLLL
                     RTLAQAAQRGERVPTPGELPTNIDERVMICPLTN"
                     /name="site-specific integrase"
     gene            <6630..6851
                     /locus_tag="I6K37_RS28040"
                     /old_locus_tag="I6K37_27510"
                     /pseudo=""
     CDS             <6630..6851
                     /locus_tag="I6K37_RS28040"
                     /old_locus_tag="I6K37_27510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012565250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="shufflon system plasmid conjugative transfer
                     pilus tip adhesin PilV"
                     /name="shufflon system plasmid conjugative transfer pilus
                     tip adhesin PilV"
     gene            complement(7472..>7594)
                     /locus_tag="I6K37_RS28045"
                     /pseudo=""
     CDS             complement(7472..>7594)
                     /locus_tag="I6K37_RS28045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001356717.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="shufflon protein C'"
                     /name="shufflon protein C'"
     gene            7775..9037
                     /locus_tag="I6K37_RS27520"
                     /old_locus_tag="I6K37_27515"
     CDS             7775..9037
                     /locus_tag="I6K37_RS27520"
                     /old_locus_tag="I6K37_27515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_031587700.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISEcp1 family transposase"
                     /protein_id="WP_000608644.1"
                     /translation="MINKIDFKAKNLTSNAGLFLLLENAKSNGIFDFIENDLVFDNDST
                     NKIKMNHIKTMLCGHFIGIDKLERLKLLQNDPLVNEFDISVKEPETVSRFLGNFNFKTT
                     QMFRDINFKVFKKLLTKSKLTSITIDIDSSVINVEGHQEGASKGYNPKKLGNRCYNIQF
                     AFCDELKAYVTGFVRSGNTYTANGAAEMIKEIVANIKSDDLEILFRMDSGYFDEKIIET
                     IESLGCKYLIKAKSYSTLTSQATNSSIVFVKGEEGRETTELYTKLVKWEKDRRFVVSRV
                     LKPEKERAQLSLLEGSEYDYFFFVTNTTLLSEKVVIYYEKRGNAENYIKEAKYDMAVGH
                     LLLKSFWANEAVFQMMMLSYNLFLLFKFDSLDSSEYRQQIKTFRLKYVFLAAKIIKTAR
                     YVIMKLSENYPYKGVYEKCLV"
                     /name="IS1380-like element ISEcp1 family transposase"
     gene            9361..10506
                     /locus_tag="I6K37_RS27525"
                     /old_locus_tag="I6K37_27520"
     CDS             9361..10506
                     /locus_tag="I6K37_RS27525"
                     /old_locus_tag="I6K37_27520"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extended-spectrum class C beta-lactamase CMY-2"
                     /protein_id="WP_000976514.1"
                     /translation="MMKKSLCCALLLTASFSTFAAAKTEQQIADIVNRTITPLMQEQAI
                     PGMAVAVIYQGKPYYFTWGKADIANNHPVTQQTLFELGSVSKTFNGVLGGDAIARGEIK
                     LSDPVTKYWPELTGKQWQGIRLLHLATYTAGGLPLQIPDDVRDKAALLHFYQNWQPQWT
                     PGAKRLYANSSIGLFGALAVKPSGMSYEEAMTRRVLQPLKLAHTWITVPQNEQKDYAWG
                     YREGKPVHVSPGQLDAEAYGVKSSVIDMARWVQANMDASHVQEKTLQQGIALAQSRYWR
                     IGDMYQGLGWEMLNWPLKADSIINGSDSKVALAALPAVEVNPPAPAVKASWVHKTGSTG
                     GFGSYVAFVPEKNLGIVMLANKSYPNPVRVEAAWRILEKLQ"
                     /name="extended-spectrum class C beta-lactamase CMY-2"
     gene            10600..11133
                     /locus_tag="I6K37_RS27530"
                     /old_locus_tag="I6K37_27525"
     CDS             10600..11133
                     /locus_tag="I6K37_RS27530"
                     /old_locus_tag="I6K37_27525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin family protein"
                     /protein_id="WP_001221666.1"
                     /translation="MRILPVVAAVTAAFLVVACSSPTPPKGVTVVNNFDAKRYLGTWYE
                     IARFDHRFERGLDKVTATYSLRDDGGINVINKGYNPDREMWQKTEGKAYFTGDPSRAAL
                     KVSFFGPFYGGYNVIALDREYRHALVCGPDRDYLWILSRTPTISDEMKQQMLAIATREG
                     FEVNKLIWVKQPGA"
                     /name="lipocalin family protein"
     gene            complement(11130..11447)
                     /gene="sugE"
                     /locus_tag="I6K37_RS27535"
                     /old_locus_tag="I6K37_27530"
     CDS             complement(11130..11447)
                     /gene="sugE"
                     /locus_tag="I6K37_RS27535"
                     /old_locus_tag="I6K37_27530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463202.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="WP_000118520.1"
                     /translation="MSWIVLLIAGLLEVVWAIGLKYTHGFTRLTPSIITIAAMIVSIAM
                     LSWAMRTLPVGTAYAVWTGIGAVGAAITGILLLGESASPARLLSLGLIVAGIIGLKLST
                     H"
                     /name="sugE"
     gene            11704..>12069
                     /locus_tag="I6K37_RS28050"
                     /pseudo=""
     CDS             11704..>12069
                     /locus_tag="I6K37_RS28050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003830562.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="LuxR family transcriptional regulator"
                     /name="LuxR family transcriptional regulator"
     gene            12205..12324
                     /locus_tag="I6K37_RS27895"
     CDS             12205..12324
                     /locus_tag="I6K37_RS27895"
                     /inference="COORDINATES: protein motif:HMM:NF025127.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4165 domain-containing protein"
                     /protein_id="WP_227639711.1"
                     /translation="MLGALAVLTAGAAHAELLEYTFKAPDGTQRSLTPNANSR"
                     /name="DUF4165 domain-containing protein"
     gene            complement(12460..13746)
                     /gene="pilV"
                     /locus_tag="I6K37_RS27540"
                     /old_locus_tag="I6K37_27535"
     CDS             complement(12460..13746)
                     /gene="pilV"
                     /locus_tag="I6K37_RS27540"
                     /old_locus_tag="I6K37_27535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shufflon system plasmid conjugative transfer
                     pilus tip adhesin PilV"
                     /protein_id="WP_015059540.1"
                     /translation="MKKTDKGVSLLEVLLVIGIMVMVIPKVYENIENHLNNVRWQNAAE
                     HANTYNTAVRNYVADNASTLLAGSLPKTITPATLIQKGYLKSGFSESNFGQSYITGIAK
                     NSKTSRLEALTCSNGGQSLSEAGMRSVASMIEGLGGYINSSKQAIGAGGGWSDTPSNYG
                     LNCATGHIAMALVGADLQESDRLYRYSITNRPDLNRMHTAIDMNSNNLNNVGTLNGNAA
                     ALSGDISARNGTFSGAISGNTATTNGDITSNNGWLVTKNSKGWMNSTYGGGWYMSDSSW
                     LRSVNNKGIYTGGQVKGGTVRADGRLYTGEYLQLEKTATAGTSCSPNGLVGRDSTGAIL
                     SCQSGTWKKIGAGDSQIVTASATAWRWPGATATCPSGKKVIGGGGQCRSNTGFIWLTRS
                     MPSGNNAWTASCDTTEDQNGSITVYAICQ"
                     /name="pilV"
     gene            complement(13759..14394)
                     /locus_tag="I6K37_RS27545"
                     /old_locus_tag="I6K37_27540"
     CDS             complement(13759..14394)
                     /locus_tag="I6K37_RS27545"
                     /old_locus_tag="I6K37_27540"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934977.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="WP_000934977.1"
                     /translation="MLNSIFNTAILCCANIVCQCYAYNEVKFRLNKLNVSYKTGAEKYY
                     CLILTTLAVMYLSLNQLSLIQSIIVIIFYAFLTLMACIDLLSFLLPRLYTVTFIFSGLL
                     YQTWNNNILSGLFCAILMFFIMLFVRLYFAYKNGTESFGMGDVLLIAGTGVWFPTPEIA
                     CSIVFIAVIGGIIFFTLGGLNKQKKYIPFGPFLCGGMFVYSLVPGILF"
                     /name="A24 family peptidase"
     gene            complement(14398..14880)
                     /locus_tag="I6K37_RS27550"
                     /old_locus_tag="I6K37_27545"
     CDS             complement(14398..14880)
                     /locus_tag="I6K37_RS27550"
                     /old_locus_tag="I6K37_27545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001258095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_001258095.1"
                     /translation="MRSVLYILLSCISSLIFSLQPAYSATTTRFDACFAQAGQRYLIDP
                     LLLKSIATVESSLIPDRINHNKEKGKILSTDYGLMQINSSHIPNLKKLGVIKDKSELID
                     NPCLNIQIGAWILATHFQKCGINWSCLGSYNAGFKESNEQKRIKYARYVYNKYMVR"
                     /name="lytic transglycosylase domain-containing protein"
     gene            complement(14946..15503)
                     /locus_tag="I6K37_RS27555"
                     /old_locus_tag="I6K37_27550"
     CDS             complement(14946..15503)
                     /locus_tag="I6K37_RS27555"
                     /old_locus_tag="I6K37_27550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4 pilus major pilin"
                     /protein_id="WP_000095048.1"
                     /translation="MSSINILNMRSVFSSLSARRKKEQDKGATLMEVLLVVGVIVVLAA
                     SAYKLYSMVQSNIQSSNEQNNVLTVIANMKSLKFQGRYTDSNYIKTLYAQGLLPSDMIA
                     DTTGASAKNPWGGSVTITTSSDKYSFNVVEANVPQKNCMAMVNALRSSSAISKINNTST
                     STVSAATVCASDSNTLTFSTDS"
                     /name="type 4 pilus major pilin"
     gene            complement(15548..16657)
                     /locus_tag="I6K37_RS27560"
                     /old_locus_tag="I6K37_27555"
     CDS             complement(15548..16657)
                     /locus_tag="I6K37_RS27560"
                     /old_locus_tag="I6K37_27555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="WP_000974903.1"
                     /translation="MAIKDIFEKLNSIEIDFSGISHWLAKYTFRYSRISLYEDLSGMLN
                     DGINVKRALTHLIDVETDYGKKTGSSATYYICCECLNALNNTGAISSALKKYIKEDEYQ
                     LISSGEIRGDLAGGLVQAIKIVRSRSEMTMTLVMSMIYPSVLVFGCLANMYMVHDTITP
                     VFLSLAPKERWTSSMRLLTDTSGFLIENGTYILCFCIVLFFLIRYSLARYTGPGRQYLD
                     YIPPWSLYKTFNGVSFLFNMASMLSIDIPVAKALERLEKNSTQNRWLLERIKEIRRYVL
                     LGQSLAMAMKSCGYDFPSKLCINKLLLHSENADNALMMSNYADKWLEEAKGKVKSTGVW
                     ITVVSALIVFAFIVMMITALYDVSNVLQH"
                     /name="type II secretion system F family protein"
     gene            complement(16648..18186)
                     /locus_tag="I6K37_RS27565"
                     /old_locus_tag="I6K37_27560"
     CDS             complement(16648..18186)
                     /locus_tag="I6K37_RS27565"
                     /old_locus_tag="I6K37_27560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase, T2SS/T4P/T4SS family"
                     /protein_id="WP_000466225.1"
                     /translation="MFFSDADYPGKDISDVVYVSISEKDDKPVHVYIADNSKGQRAVQA
                     YIGTLNVKYPGKVNITWTTLDVIASRYQDSERRSDSNSSQHLNSNQEKVISYLAKANNL
                     GSSDLHITPGRDGSEFTYVEARVHGELEILDVIPRKEGLELLGAAYSGMSDVIKGTQFD
                     PAIPQDARIAENFLKPVNLFGARYSHYPCVGGVYAVFRLIKDDSEDIPTFEELGYMPQQ
                     IQTIRRMLQRPEGIIVLSGPTGSGKSTTLRTASEAYLSTFGFNHNDNMRLPRKRLFTIE
                     SPPEGRIPGAIQTAVRDSVDGWVDAIKSAMRLDPDAILNGEIRDHASALAAIKASMTGH
                     LLLTTLHANDALNIIERLEMENIQARLIADPLLFIGLLSQRLVQKLCPYCKRTYAEMAD
                     KLSTEERKLIEENCLPEQVRLRNLDGCEHCYKGVTGRTVIAEVVSPDARFFQLYRQSGR
                     LEAKSYWHYELGGITRNQHLLHLINHGLVDPLSAHFISPIDEDKYSMLPEGTWR"
                     /name="ATPase, T2SS/T4P/T4SS family"
     gene            complement(18211..18705)
                     /gene="pilP"
                     /locus_tag="I6K37_RS27570"
                     /old_locus_tag="I6K37_27565"
     CDS             complement(18211..18705)
                     /gene="pilP"
                     /locus_tag="I6K37_RS27570"
                     /old_locus_tag="I6K37_27565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401690.1"
                     /GO_process="GO:0009297 - pilus assembly [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus biogenesis protein PilP"
                     /protein_id="WP_000912553.1"
                     /translation="MLKIIKPTIISVCFFSSLAYATESESTPKDEIKYSSPTILQVEQI
                     QAETVIYEAKLARQKAVSELRNLDLNGVASATPAITPSSGYSSLADTDIPAQRVAAKSL
                     RVIEIFGTPQQMSARISLLDGSVTDVKVGQSIPGTSYKVASITGNGVWIQNGTEKRQLI
                     L"
                     /name="pilP"
     gene            complement(18689..19999)
                     /gene="pilO2"
                     /locus_tag="I6K37_RS27575"
                     /old_locus_tag="I6K37_27570"
     CDS             complement(18689..19999)
                     /gene="pilO2"
                     /locus_tag="I6K37_RS27575"
                     /old_locus_tag="I6K37_27570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001360347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4b pilus protein PilO2"
                     /protein_id="WP_001454111.1"
                     /translation="MSENNQNNRNFTSVIKNKRAFFSGLDWKTLPSEEKNARTFARKND
                     AEYFLSCQYQDSENETKTMVAFIRKEDLPTGASSFWSLALMIKPLIEPDGYAICELGDL
                     YGFVSCVNNVLVNDVVGNKSQIMSALTTFLEFNETPEPGWKLYQPESWDISQALPSLTL
                     SALIDVKKPPKEAAFTRVSRKRQFMIYGGSAILAILLWNGITMYQEYREKEAAAEAARL
                     RLAKEMADKQAIQIAPPWQHLPEIKPFIDKCIDKWDALPLSIAGWRFDLAECSTSGNDG
                     LLRTSYKELSGVTVEDFSTRIREIFQGTTTATFVLPEGSAGGFSLPVSFDVSPDPITPD
                     TLPQATDIQERLTTFAQKMRLKLTWQEIENTKTDEEGRPIILPWNEYELMIQTSTPPSI
                     LFANFHEPAVRFQYAGIKLEEGRLNYEIKGAFYVKNN"
                     /name="pilO2"
     gene            complement(20050..21693)
                     /locus_tag="I6K37_RS27580"
                     /old_locus_tag="I6K37_27575"
     CDS             complement(20050..21693)
                     /locus_tag="I6K37_RS27580"
                     /old_locus_tag="I6K37_27575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035590.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0009297 - pilus assembly [Evidence IEA];
                     GO:0009306 - protein secretion [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN family type IVB pilus formation outer
                     membrane protein"
                     /protein_id="WP_001035592.1"
                     /translation="MNKKLLCLLISSFLLSGCANFKKINTNELAAEKDAQKATEYAKKI
                     RNNPVIQDSTKQWINTTPIIEKQVKQSAPPCPIVINTRSDIELRQIAQRITQTCHIPVR
                     ISADVWTYLNGTGTGSTQQMTGSIPAPDANGMVPLASVGSQPVKVSSGGTSLPELNISG
                     LPALLQTVSSRLGISWKYDKGRITFFYLETRSFPITYMDSNVAYNSKVVSGTMSSSGST
                     GSTSSGGMTGDASNTQTTTVEMKSSLYNDLKSEVSSMLTPGTGRMYLSTGSLTVTDTPD
                     VLDSVQEIVNKRNNEMSRQVVLNVEILSIKKSSQEQAGIDWNAVFNDGHLGLSLGGSFG
                     NAAENVITSGVSIVDGKLAGSKAFLKALSSQGSVSVVTQNSAVTKNLTPVPMQIANQQG
                     FIESVTTDSTANVGSSTSLNAATITTGFNMTLLPYIQPDSQNLQLLFSMSLSDKPTFEV
                     FESGGSKAQTPNVDLKTINQTIDLKSGQTVILSGFQQSNRKTSKQGVITPSFFGLGGGI
                     NSEDGDTILVVLITPNVLNSGSSAVIKNVN"
                     /name="PilN family type IVB pilus formation outer membrane
                     protein"
     gene            complement(21686..22216)
                     /locus_tag="I6K37_RS27585"
                     /old_locus_tag="I6K37_27580"
     CDS             complement(21686..22216)
                     /locus_tag="I6K37_RS27585"
                     /old_locus_tag="I6K37_27580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001708008.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0008134 - transcription factor binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="WP_001220542.1"
                     /translation="MRIKHSNMINMNMNMNMMKEAIDVLINSEKHILIIGETGTGKSTL
                     LAELLINDTDVKYFDFCDIYKRHEHLPLLKHHYLCDENFDYFDFLSAPEKTLVLNSVAI
                     GNNLRESKVVQFIVRFIKTARKRGKRLIVVTTPSDGGVQIQNLFDTVISLTRSHDEIGC
                     TVIIPVPELIKYE"
                     /name="sigma 54-interacting transcriptional regulator"
     gene            complement(22263..24221)
                     /locus_tag="I6K37_RS27590"
                     /old_locus_tag="I6K37_27585"
     CDS             complement(22263..24221)
                     /locus_tag="I6K37_RS27590"
                     /old_locus_tag="I6K37_27585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338972.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA transfer
                     family protein"
                     /protein_id="WP_015059539.1"
                     /translation="MNAKKMGGLILFLLLLLVGVLIASNYLGGYTALRYSSVDMSLLKW
                     DTFHSVISTFSGNPQYKKLVFMAWFGFSVPLIFFAIFMLIVVIGIMPKKVIYGDARLAT
                     DMDLSKSGFFPDKKSPYKHPPILIGKMFKGRYKKQFIYFAGQQFLILYAPTRSGKGVGI
                     VIPNCVNYPGSMVILDIKLENWFLSAGFRQKELGQKCFLFAPAGYAETIDQAIKGQIRS
                     HRWNPLDCVSRSDLLRETDLAKIAAILIPASDDPIWSDSARNLFVGLGLYLLDKERFHL
                     DQKAKGHNAPDVLVSISAILKTSIPDNGKDLAAWMGQEVENRSWISDKTKSFFFEFMSA
                     PDRTRGSIKTNFSSPLNIFSNPVTAEATNFSDFDIRDIRKKPMSIYLGLTPDALITHEK
                     IVNLFFSLLVNENCRELPEHNPDLKYQCLILLDEFTSMGKSEVIERAVGFTAGYNLRFM
                     FILQNEGQGQKSDMYGQEGWTTFTENSAVVLYYPPKSKNALAKKISEEIGVRDMKISKR
                     SISSGGGKGGSSRTRNDDVIERPVLLPEEIVSLRDKKNKARNIAIREIITSEFSRPFIA
                     NKIIWFEEPEFKRRVDIARNNHVDIPNLFTQEVMDEIAKIAEIYLPKAGGKKVMVAGGN
                     VITNPDLDNHDKTDVSE"
                     /name="type IV secretory system conjugative DNA transfer
                     family protein"
     gene            complement(24237..25292)
                     /gene="virB11"
                     /locus_tag="I6K37_RS27595"
                     /old_locus_tag="I6K37_27590"
     CDS             complement(24237..25292)
                     /gene="virB11"
                     /locus_tag="I6K37_RS27595"
                     /old_locus_tag="I6K37_27590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001708009.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_001059977.1"
                     /translation="MNNIRDTSNTSQPRDNSKTARRYLDMTGIQSVLNIEHVTEISVNK
                     PGTIWFEGKNGWESKDAPDATFDNLMTLAKTLTNLSKIKIPLSHDNPIASVVLPGGERG
                     QIIIPPATENNSVVISIRKPSLTRFTIDDYVRTGRFDNVRIATKHEAILTERQRYLYEL
                     SRRPDGQSKAQFLREAVKDRLNFLIVGGTGSGKTTIAKAIADIFPPERRYITVEDVPEM
                     SLPLHPNHIRLFYKKNTVEAKEIIEACMRLKPDHIFLAELRGNEAWSYLEALNTGHEGS
                     ISTIHANNTYASFSRLASIVKQSDVGMTVDMDLIMRTIKTSIDVILFFNHTRMTELYYE
                     PEEKNRFLSTM"
                     /name="virB11"
     gene            complement(25311..26450)
                     /locus_tag="I6K37_RS27600"
                     /old_locus_tag="I6K37_27595"
     CDS             complement(25311..26450)
                     /locus_tag="I6K37_RS27600"
                     /old_locus_tag="I6K37_27595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001542008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbI/VirB10 family protein"
                     /protein_id="WP_000790640.1"
                     /translation="MKNKDDEKNNDAGNRGIIEVKGKAAPKKILILIILLIAALFVIII
                     LFKVLSREQVVQQTPLEKSDETLVTNTNNGVSLTTMMKNIEEKEKLDAANRRKAQEEQE
                     QKQADNAPSAPASQKADQTAVNVIANGSPQTASGDPNQPQPLPKSVRQLMGDTMVKIDN
                     QEPGEKNQERDDLQGSQYADGKVSPVLNRRYLLSAGTALSCVLKTKIVTSYPGITMCQL
                     TRDVWSDNGEVLLARKGALLIGEQNKVMTQGVARVFVNWTTLKDENVNVRIGALGTDSL
                     GASGLPAWVDNHFGQRFGGALLLSLLGDGLDILKNSTQQTGSNSNITYENTSDATKEMA
                     KTTLDNTINIPPTAYINQGTVLSVIVPRNIDFSSVYELQ"
                     /name="TrbI/VirB10 family protein"
     gene            complement(26440..27141)
                     /locus_tag="I6K37_RS27605"
                     /old_locus_tag="I6K37_27600"
     CDS             complement(26440..27141)
                     /locus_tag="I6K37_RS27605"
                     /old_locus_tag="I6K37_27600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbG/VirB9 family P-type conjugative transfer
                     protein"
                     /protein_id="WP_000274524.1"
                     /translation="MYGTPSERDGRIQTVDYNEQDVFNVRVKAGAQTTIKFGQDETIKD
                     VGIGDPEAWSVSVRDNTLFLRPKAEEPDTNVTVQTNKHIYPLYLISTTKQPTYILRFNY
                     PKPPSATVMTEKPFPCTDGGIINGHYQLKGDKSIFPYQVWDNGEFTCMRWTNKQEIPVL
                     YRVDADGNEHLVNGDRNKNTMVYYDVAENLRLRLGDQVADIRTSSIVNRPWNKKGTSNG
                     KTRVEKFSYEK"
                     /name="TrbG/VirB9 family P-type conjugative transfer
                     protein"
     ARG             9362..10503
                     /name="blaCMY-2"
                     /gene="blaCMY-2"
                     /gene_name="extended-spectrum class C beta-lactamase CMY-2"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          complement(22267..24221)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="98.16"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(26444..27210)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.609"
                     /coverage="100.0"
                     /evalue="2.88e-172"
ORIGIN
        1 aatcagggcg tatccggtat ctgttggaat aagttttcct ttttccaggg tgatatagtt
       61 ccgttttttc agcgtttcca gcatggaagc ccgcgtagct gacgtaccaa tgccaccatg
      121 ctcatccttt ttatcccgat ctttatcctt cagtaatttt ttaatcactg gatcagtgac
      181 aaaatctgcg acacgaacaa gcgcggcaag taaagtggct tcggtgaata atggcggtgg
      241 cgttgttttc ttctcattca caaccacttc ttttgtcgtc actgtttctc ctgtgcgaat
      301 tttacagagc agatcaaaag cggaatcatc attttcggct tctgattcct catccccggt
      361 attttcctca ccaagaaacg cttcaaatcc gctgtctgtt gttttcctgg cacgggcata
      421 aaacgactca tcaccacact gaatggcaac ggatacttcc tggtatgttt tttcaggcat
      481 gaactgaaca agatagtgtt gtgcgattgc caggtaaaca ttgcgctcgt cactgctcag
      541 cgcgtttaca tccggtacgt taacggtcgg gattatcgcc gtatgcgcag tcactttcgc
      601 actgttaaac gccttgcttt tacgtgtcga atcaacgtcc agtggctgat cgaatactga
      661 cttcagggca tcgagaacct gtggtgcttc gctgaattgt tcatcagaaa gatatgagca
      721 atctgaacgg ttgtaagtaa ttgctttgta tttttcacgt agctgctgtg tgatatccag
      781 cgtttgttgt gccgtcattt tgaacttctt gttcatgtac tgctgaagcc ggaccaggtt
      841 aaagggcaat ggcgcagccg tttttttatc gtctgttgct gctgcttcaa ctgtcgctgg
      901 ttttcctgca agggaagccg ctgttccatt cgcccacgcc ttatcaagta atttacggtc
      961 tgtcagtggt gcgaactcac caggtttcca gttcgccctg ataacatcaa cgccgcgttg
     1021 aaaatgcccg gtcatggtgt agtagaaact ggatttatga ttcttgttgg cacgggtgcg
     1081 atttactatc aggccaagaa taggcgtctg aacacgcccg accgaaagtg tccctttata
     1141 gcctttagcc cgtgccggga tcgtataagc acgcgtcatg gataaaccgt atatcgcgtc
     1201 ggctacagaa cgcgccagag ccttgagata gagtcctctg aagtcacggt tatttttggg
     1261 atttgccagt gcctttttca ctgccggaag ggtgttgtcg ttgatcagaa cgcgcttaac
     1321 gggttttgtg ttgcctgcat attccaggac ctcatcgaca agtagctgtc cttcgtcatc
     1381 tggatcgcca gcatgaataa tttcggtcac atcagcacgc ctgataagct caataatcgt
     1441 tttaacctgt ttttcggcgc tttctacagg ctggtatttt acgggataaa gacgcaaagg
     1501 gagtgtttca atcttccact ctttgtattc aggattatag ttttcggggg gctgtgattc
     1561 gataatatga ccaaaacagt tagtcacaat agtattatca ctttcaaacc agccatcatg
     1621 acgggtaaaa ttgccaccaa gcgccttaac aatatcattc gctactgcgg gtttttctgc
     1681 gataaaaagt ttcattttgt tatcctttac attgaattaa tcttttggca caacggatag
     1741 cacgttcttc tgatactgcc tgttgccagt tatcttcact tactggatgt ctgaatctgc
     1801 gttcacagcc attaaaagca aaaatcccct cacggttaag tatattagtt gcaatatcct
     1861 ggtctttaat tctcaaaaag gctgttacgg caaaaccaga atacgaagaa atttttgaaa
     1921 tgatgcattc atcagctttt attaacgcgg caaaaggaac tatcttttga tgaccacacg
     1981 aaatcagagg gagtgtgtga atatcataat aagctattga atgacaatcc atgcgggtat
     2041 catcaatagc tgccagccag aatcctgtct ggtcttttat ttttctgata atatctgaat
     2101 ctgaaacacc aggatttaat aaatatccac cataacagac atggaagggg tgagcagatt
     2161 catcaatatc aggaagttct tttaccggat tttctttcca gtccttcaga acaccgaatt
     2221 caagagcatc cagcaaaaac tttcgttcaa atccatcaag caatgcatat tgcatgttaa
     2281 acctctcaaa gaagctctga tttgttgacc tcatggtgaa ccagttcacc attgcgtaag
     2341 acaaacaggt aagaaaactt tctttcctta tctttcagtc agtttttgta ttcagaaaga
     2401 ataaacaccc agtcatcggt gctgtaatga gatgcgatga ctcattatct ttttagtgat
     2461 gagttgatta tttttaaaat atgcctgcct ttaattagca tgtttctgga aacagcctga
     2521 ttacgaatac ctctcatctg gtcaaactga taggttaaat catgttcttt tcgtgaaagt
     2581 ccaagagtgg ctctttcatt atccatcagg actgaaattg caatatattc tccagatgca
     2641 caccagtctg cataactggc aacgcaatgt tccatctcct gaccttcctg acacagagca
     2701 tcaaatgtaa ttaattcatt tacaccgtta tcaactttct gccagtttat cccagttcct
     2761 ttccattttg ggattacggg aataacgtta ttcttcactt gtcgcgtcca ttcatcagat
     2821 agtctccaga aagaaggcca ctcctggttt ttatgaatta accgttcttc tgctaacaac
     2881 cagtcaattg catgacacaa ctgattcgtt tccatttccc agcgtgatgt ttgcctggat
     2941 tcagtattac ggtcataaaa gccaatgttt ttaaataaat cacgatgata ttctagccat
     3001 tttgagcata tacgataaat atcattttct ttttctgggt aagctcgaat gctaatataa
     3061 tcgataatcc agtaaattgc tctcacagga tagttcttga taagtggatg gcgtaataat
     3121 ctgactgtaa atctgaatga tgcattatca tgtttatcat ttaaagcata tactaatgac
     3181 aaactaacat gtcgtaaact tctgaactca ccataactaa gtttgcaggg aaaactgatt
     3241 ttttcatata actcttttgt ctttccagat agtataaact gaccattttt atgttgttgt
     3301 cttagacgac caaccatagg ccacaatccg aaaaaatcca tatcattcac aatatggatt
     3361 cgctttgaaa aatccagata gtcctcaaat aatgcctgac gaattgaatt gtaagctatc
     3421 gaacaatgtg aagctctggc atattgtgca aatatctttt tatctaccat tatccatata
     3481 gctttactca atgcttttga agcattaaat tcattatcca tccctataat ttttaatgct
     3541 ctctgataaa ttttgttttt tatctctgcg agtaaaatat gtctgctgat atatcgtgta
     3601 ttataggggt agttgaatga tgctatttta ccaaggcaat gaacaatgtc atgtattcca
     3661 tactcatatg agtaatatac attggatgga tatagtgtgg aaatataacg actctcactg
     3721 ttttcctctt cctctccaat gcgtaacaaa tagagtttgt cttcaattga atatccagcc
     3781 tcaatcaatg atttgatgat gtagctaatc gcatatttta accagtcgtc catgtcgtat
     3841 gcagattttt tagaccagaa taaaaaaatc ttaccaggaa atgaatttct tctggtccat
     3901 accccagtgt gcttatctct tagcttgtat ccccacaaag tgattttgtt attctttttg
     3961 ttttttctaa tacgaaaaac gccacaaatg ataatggaga tgtacttttc attctcctct
     4021 gtttttacaa gacgaagccc ccctgtattt tgatagattt taaaaacatc atgcaacgta
     4081 agaatattat tgtcccttgt ctgttgatta attacataca tgccgccccc tgttaaaaag
     4141 aagcctttaa tattgcacaa agataaaaag acagaatcat ggcaaaccaa aagaagaatg
     4201 cattttcttg cccccttaat ttctgatacg ccattcccac ggtggaaccg gatttacatc
     4261 ggcccacaaa ccacgttttt gttcctgcgc ttcccgttgc agagccggta atgactcatc
     4321 cacgttgtaa cgttcatata cccatgcagc gccagactga accataaagc ggctggcatc
     4381 cgtgccgttc gtcgtgaaca catgaccgat aatgcgtccg tagcggtctt tatgtgaata
     4441 agagactgtc acctgtttac ctgcaaccag agttttaagc tgactagttg accagcgtcc
     4501 aaaaggttgt ttcttttcag gggcatcgat gtttatcaat cggactcgga tcggaacttc
     4561 atacacaaca atttttgcgg gtagtgtttt aatttctatg gtgtcgccat cgagaacgcg
     4621 aataactttc ccctgaagaa ttttctggtt aaatgtataa ggtattccac ctgcatttgc
     4681 agactgaaaa gcggtaagca gataaataaa tattgttaat aagattttca taaaagatta
     4741 acgttaattt gtctgtgcaa tggatagagc gttattctta ttttcttcct gctgcttcat
     4801 cgaaaaatga tgattttcct actgctgcgg catcatactg aaatgaatat ccaaaatcat
     4861 cgtcatgctc aaaacctgta ttttctccat tttttagtct ggaaagaata atctcaagtt
     4921 gactgattat atcttccctt tcactatgac gagtgccttg taagagaata gttacttgtt
     4981 gcaaaggata tgcatgttca atccatgcct ggctaggtcc agagtgcgtt gtatataaat
     5041 ttttttgtgc cgaaatatta ttcagaaaac agtttaagtc atcattggaa taaatttctt
     5101 taatattgtt gatgttggat gttagtttta caagttggaa tggtggagaa tttttgtctt
     5161 cattgttgtc tcctttatcg tattctggaa acacaattaa caaaggtgca ccattagttc
     5221 tcttcataaa acgggttact agccgcccaa tatatttatt ggacatatgc tgttcaatgt
     5281 ccaggacagc atattcctcc gctgggaaca ttttgttttt ttcgatggat ttaatttttc
     5341 tggtaagatg aatatttctg ataagcaaac ctactatcag gaagtaaata aatatccaga
     5401 ataaaaaatc actctgtagt tgttctatca taagtgaatc ctctaatttg ttaatggaca
     5461 aatcattacc cgttcatcaa tgtttgtagg aagttcgcca ggagtaggga cgcgctctcc
     5521 tcgctgggcg gcttgtgcca gtgttcgtag cagcaacacg ctggcatgaa atatggcctg
     5581 ttcttttgtg gctgcgcttg tttccaggtc gaaatcactc agagtcacaa cgacttgccc
     5641 gtttctgttc tcgaccgttg ccgggtaggg aacaaaatag ggagcgattt tgctggtttg
     5701 cttgcgtcgg gcatcgagtt tactgacaag ttgataagcc cgaaggtgtg tgtatcgttt
     5761 caacatgttc agggagcgat ggcctgaaat agcggcaacc tcaatgacgt tcaatgtacc
     5821 aagttcgaaa aatcggctga tggcctcatg acggaggtca tgaaaatgca aattttctat
     5881 cttcagttcg tgaagtgctg ttcgccaggc acttttgaat cccgaagagg tataagaaaa
     5941 aatattaccg ttaagctgtg tcggcagcat ttgcaggtaa ttacgggctt tcctggatag
     6001 cggaacatcg cgtggagcac cgtttttggt tgttggaaga tgagctaccc catgttgcag
     6061 atcgacgtgt tcccaacgca atgacaagat ttcaccttgt cgcattgctg tttccagcgc
     6121 cagatgaaaa atgacgtaaa gagcctgatt tttttctttg aaataccgcg aaagtcggcg
     6181 ttcttctcct gaagtcaggc gacgatcgcg cccgctactg attttgggtt ttctgaccag
     6241 ttcgacagga ttcatgcggc atgttcccca ttccacacgg gcgatattga ataatgatga
     6301 caacagggca agttcaagac ggacggtgtt tccggttatt tgacgccccg ttcgggggtt
     6361 aatttgcgcc aaccgttgat cccgataatt ggcaatatca acagtggtaa tgtcatccat
     6421 atagcgttca gcaatagggt gacgtttaat cacatttacg cgataaaact cctgtagatg
     6481 gccttttttg tggatggata ctgtcttcag gtatttgtcc agcgcccggc tgattgtcat
     6541 tttgcgaatt ttgattttct gaaacatatc ccctccagac aaaaaagggg ggaaggtaga
     6601 gattcttgct tcgaaatgca atatcaccgt gccaatccgg tgtgtggagg gcattaggtg
     6661 gaaagctcaa ggttactcaa ctttccagca ctggttactt ggggcaattt gacttttgtg
     6721 ccattgccag aatgggaaat gctgaggatt ctcattactg ccaggtagtc gagagtccat
     6781 ctggttcacg aaaatggtac aaatacgagc acaagacagg ttgtattgcg tcctgtgtaa
     6841 ctctcaatta agtctggtat ccaaatactg aaaatacccc tgagccacaa gagtagtttt
     6901 gggccggata agaggtgatc tgataagttg cgccagcagg gacagcaaaa gagatgaatg
     6961 ctgtcttccc ataagatggg ttgttgctcg catttgtgct aatcaatgcc cctgcaacgt
     7021 atccctgcaa tctggatgtg ttagcgcaat ctcccccggc ggaaccacca ttccctccag
     7081 aggcgtaaac aaacagcgta ccacttcctg tattgcgacc agtaaatgat cctctgtgtg
     7141 agccaagatt actgtaacta ccgttagagg aaccggaagt tctccacaca ccggattggc
     7201 acggaggcca gtgccaatcc ggtatctgga caacggcaaa agtgaacttc actaccagta
     7261 cgtacaatat cgggaaaaac acccgaaatc tgagcattgg cgtacatgcg tactgttcgt
     7321 ggacatacct taatggtgcg ccttttggtg ggtttcagca ggtatactcc gaccaaaaca
     7381 aggtttggta tgtgaataat tatgcgtggg gaaattatga gtccggcggc acaattactg
     7441 ttacatgcct gaatcttcct ggtgctggga tttaaccgaa ggggcaacaa taagcatcaa
     7501 cgtgttcctc atcaacgcca tcaccaatgc catacatgcg tgtacctgtc atgataaatc
     7561 cggtcgggca ttgaatgggt ttgtagtacc tagattctac gtcagtactt caaaaagcat
     7621 aatcaaagcc ttgataaata tgcattcctt cgaaattcag ctttcaccca ttgggtgaaa
     7681 gaaaagtgct caaaaatatg ttaaattatc agcttttatg actcgatata tggtaaaata
     7741 atagtaagaa aagtagtaaa aaggggttct aattatgatt aataaaattg atttcaaagc
     7801 taagaatcta acatcaaatg caggtctttt tctgctcctt gagaatgcaa aaagcaatgg
     7861 gatttttgat tttattgaaa atgacctcgt atttgataat gactcaacaa ataaaatcaa
     7921 gatgaatcat ataaagacca tgctctgcgg tcacttcatt ggcattgata agttagaacg
     7981 tctaaagcta cttcaaaatg atcccctcgt caacgagttt gatatttccg taaaagaacc
     8041 tgaaacagtg tcacggtttc taggaaactt caacttcaag acaacccaaa tgtttagaga
     8101 cattaatttt aaagtcttta aaaaactgct cactaaaagt aaattgacat ccattacgat
     8161 tgatattgat agtagtgtaa ttaacgtaga aggtcatcaa gaaggtgcgt caaaaggata
     8221 taatcctaag aaactgggaa accgatgcta caatatccaa tttgcatttt gcgacgaatt
     8281 aaaagcatat gttaccggat ttgtaagaag tggcaatact tacactgcaa acggtgctgc
     8341 ggaaatgatc aaagaaattg ttgctaacat caaatcagac gatttagaaa ttttatttcg
     8401 aatggatagt ggctactttg atgaaaaaat tatcgaaacg atagaatctc ttggatgcaa
     8461 atatttaatt aaagccaaaa gttattctac actcacctca caagcaacga attcatcaat
     8521 tgtattcgtt aaaggagaag aaggtagaga aactacagaa ctgtatacaa aattagttaa
     8581 atgggaaaaa gacagaagat ttgtcgtatc tcgcgtactg aaaccagaaa aagaaagagc
     8641 acaattatca cttttagaag gttccgaata cgactacttt ttctttgtaa caaatactac
     8701 cttgctttct gaaaaagtag ttatatacta tgaaaagcgt ggtaatgctg aaaactatat
     8761 caaagaagcc aaatacgaca tggcggtggg tcatctcttg ctaaagtcat tttgggcgaa
     8821 tgaagccgtg tttcaaatga tgatgctttc atataaccta tttttgttgt tcaagtttga
     8881 ttccttggac tcttcagaat acagacagca aataaagacc tttcgtttga agtatgtatt
     8941 tcttgcagca aaaataatca aaaccgcaag atatgtaatc atgaagttgt cggaaaacta
     9001 tccgtacaag ggagtgtatg aaaaatgtct ggtataataa gaatatcatc aataaaattg
     9061 agtgttgctc tgtggataac ttgcagagtt tattaagtat cattgcagca aagatgaaat
     9121 caatgattta tcaaaaatga ttgaaaggtg gttgtaaata atgttacaat gtgtgagaag
     9181 cagtctaaat tcttcgtgaa atagtgattt ttgaagctaa taaaaaacac acgtggaatt
     9241 taggaaaaac ttatatctgc tgctaaattt aaccgtttgt caacacggtg caaatcaaac
     9301 acactgattg cgtctgacgg gcccggacac ctttttgctt ttaattacgg aactgatttc
     9361 atgatgaaaa aatcgttatg ctgcgctctg ctgctgacag cctctttctc cacatttgct
     9421 gccgcaaaaa cagaacaaca gattgccgat atcgttaatc gcaccatcac cccgttgatg
     9481 caggagcagg ctattccggg tatggccgtt gccgttatct accagggaaa accctattat
     9541 ttcacctggg gtaaagccga tatcgccaat aaccacccag tcacgcagca aacgctgttt
     9601 gagctaggat cggttagtaa gacgtttaac ggcgtgttgg gcggcgatgc tatcgcccgc
     9661 ggcgaaatta agctcagcga tccggtcacg aaatactggc cagaactgac aggcaaacag
     9721 tggcagggta tccgcctgct gcacttagcc acctatacgg caggcggcct accgctgcag
     9781 atccccgatg acgttaggga taaagccgca ttactgcatt tttatcaaaa ctggcagccg
     9841 caatggactc cgggcgctaa gcgactttac gctaactcca gcattggtct gtttggcgcg
     9901 ctggcggtga aaccctcagg aatgagttac gaagaggcaa tgaccagacg cgtcctgcaa
     9961 ccattaaaac tggcgcatac ctggattacg gttccgcaga acgaacaaaa agattatgcc
    10021 tggggctatc gcgaagggaa gcccgtacac gtttctccgg gacaacttga cgccgaagcc
    10081 tatggcgtga aatccagcgt tattgatatg gcccgctggg ttcaggccaa catggatgcc
    10141 agccacgttc aggagaaaac gctccagcag ggcattgcgc ttgcgcagtc tcgctactgg
    10201 cgtattggcg atatgtacca gggattaggc tgggagatgc tgaactggcc gctgaaagct
    10261 gattcgatca tcaacggcag cgacagcaaa gtggcattgg cagcgcttcc cgccgttgag
    10321 gtaaacccgc ccgcccccgc agtgaaagcc tcatgggtgc ataaaacggg ctccactggt
    10381 ggatttggca gctacgtagc cttcgttcca gaaaaaaacc ttggcatcgt gatgctggca
    10441 aacaaaagct atcctaaccc tgtccgtgtc gaggcggcct ggcgcattct tgaaaagctg
    10501 caataactga cgatgaggcc caggatattg ggcctctttt ctttctcttt ttttcctgtt
    10561 gtcatctaca cttaacaaaa atacagcaag gaaaatccca tgcgcatttt gcccgtcgtt
    10621 gctgcagtta cggctgcatt cctggttgtc gcgtgtagct ccccgacacc gccgaaaggc
    10681 gttaccgtgg taaataactt tgatgccaaa cgctatctgg gaacctggta tgaaattgcg
    10741 cgcttcgacc atcgtttcga gcgcggattg gataaagtga ccgcaacata cagcttgcgc
    10801 gacgacggcg gcatcaacgt tattaacaag ggctataacc ctgacaggga gatgtggcag
    10861 aaaacggaag ggaaagccta tttcaccggc gacccaagca gagccgcgct taaggtttct
    10921 tttttcggcc ccttctatgg cgggtataac gtaattgcac tcgaccggga atatcgtcac
    10981 gcgctggttt gtggtccgga tcgcgactac ctgtggatcc tttcacggac ccctactatt
    11041 tcagatgaaa tgaaacagca aatgttagcc atcgcgaccc gggaagggtt tgaagtgaat
    11101 aaactgattt gggtgaaaca gcctggcgct tagtgagtgc tcagcttcag accaataatg
    11161 ccagcaacga tcagcccaag gctcagcaaa cgtgccgggc tggcagactc acccagcagc
    11221 aaaatccctg taatggccgc cccaacagcg ccaataccgg tccagaccgc ataagcggtt
    11281 cctacaggca acgtgcgcat tgcccaagag agcatggcga tactgacgat catcgccgca
    11341 atagtgataa tgcttggcgt aagacgcgta aaaccgtggg tgtatttcag gccaatcgcc
    11401 cagacaactt cgagcaaacc tgcaattaat aaaacgatcc aggacatatc aggttccaga
    11461 acaatggggc cgtccccggt gaaagaagcg tttgcaggtc gtcctgcaaa gctaatgtgt
    11521 gaaatggcat ttttgcccgg aagaaaatga atttcaacct ttttattcac cgcctgctaa
    11581 aagcaagaat taagcataat tagcggcgta gttcccgcat ttggcactca tcggagttct
    11641 ctatgatgaa gggctttctg aaaccagaaa gtcgattgcc cctcttctga atgcgaaacg
    11701 tttatgctta aaattttagt gattgaccgg tgccacttta cccgcacagg gatagaggcc
    11761 ttgcttaatc attctggcag gttcagctcc tcatttctgg tatcaggaat caataatctc
    11821 ctgttagcaa aagagcatat tttgcaatgg aaaccgcatc tggtgatcgc ggatttatac
    11881 agttttatta gcgagacgca ctccagtccg ccaattaaac ctttttttat gagttgtggc
    11941 gtcatcccac taattttact gcaatcagca gacagacagc atgcacccat cgtgccctct
    12001 caatccgtag cccattcggt cttgaccaag cacaccacgc tgaacacact ctcccacaca
    12061 attcaggatt tccttatttg ctcaaaaagg gcacttccac agcccatgtt tatgcactcc
    12121 ctcccgtaac ctccagcatt gggttcttgt aactcaaaac gaatggagaa tgcgatgatc
    12181 aatttcaagc ctaaaattcc ggcgatgctt ggggctctgg cggttcttac cgctggtgct
    12241 gctcatgcag agctgctgga atacaccttt aaggctccag atggtacgca acggtctctg
    12301 actccgaatg ccaatagtag atagatcctc cacttttccc gccaatgaag tgattcattg
    12361 ctacagatga ttgataccac ttacaggcgg agtagttcac tttattgcca ccagaccacc
    12421 gaccggattg gcatcgtggt ttgccagtga taagtatcgt cactggcaaa tggcgtaaac
    12481 tgtaattgaa ccattttgat cttcggtcgt gtcgcaactg gcagtccatg cattgttgcc
    12541 tgaaggcatg gaacgcgtga gccatataaa tccggtattt gatctgcatt gaccgcctcc
    12601 accaatgact ttcttgccag atggacatgt tgccgttgct ccaggccaac gccacgcagt
    12661 agctgaagcg gtaacaattt ggctatcacc tgcgccaatt tttttccacg taccggattg
    12721 gcacgaaagt atcgcccctg tactgtcgcg gcctacaagc ccgttagggg agcaggaagt
    12781 gccagccgtt gctgtttttt caagctgtaa atactcgcct gtatagaggc gtccatcagc
    12841 gcgtacagtt ccacctttta cctggccgcc agtataaatc cctttattat tcacgctgcg
    12901 caaccaggac gaatcggaca tataccagcc gccaccatag gtactgttca tccagccttt
    12961 gctgtttttt gtgaccagcc agccattatt cgaagtgata tcgccgttgg ttgtggctgt
    13021 atttcctgaa attgcgccag agaacgtacc gttacgtgcg ctgatatcgc cggagagcgc
    13081 ggcggcgttg ccgtttaaag tgccgacgtt gttcagattg ttgctgttca tatcaatcgc
    13141 cgtatgcatc ctgttaaggt cgggacgatt ggttatggag taacgatata aacggtcgct
    13201 ttcctgcaaa tcagcgccaa caagtgccat tgcaatatgc ccggtcgcgc agttcagccc
    13261 gtaatttgaa ggcgtgtcag accagccgcc acccgcgcca atcgcctgct tgctgctgtt
    13321 gatgtagccg ccaagccctt caatcatgct tgctaccgag cgcattccgg cttctgacag
    13381 ggactgaccg ccattactac aggtcagggc ttccagacgg gatgttttgc tgttctttgc
    13441 aataccggta atgtagcttt gtccaaaatt ggattcagaa aaaccagatt tcagatagcc
    13501 tttctgaatg agtgttgctg gcgtgattgt tttgggtaaa gagccagcaa gtagtgttga
    13561 tgcattgtca gcaacataat tacgaacagc ggtgttatag gtatttgcgt gttctgctgc
    13621 attctgccag cgaacattat tcagatggtt ttcaatgttt tcataaactt tagggataac
    13681 catcaccatt atgccgatga caagcaatac ctcaaggaga gatacacctt tatctgtctt
    13741 tttcattgct cttaatcctc agaataatat tcccggtacg agtgagtaaa caaacattcc
    13801 gccacaaaga aatgggccaa atgggatata ttttttttgc ttgtttaatc cgccaagagt
    13861 gaagaaaata attccgccga taacggcaat aaatacaatt gaacaggcaa tctcaggcgt
    13921 tggaaaccat acgccagttc ctgcaataag tagcacatct cccatgccga aactttccgt
    13981 tccgttttta tatgcaaagt aaagtcttac aaacagcata atgaagaaca tcagtattgc
    14041 acaaaacaaa ccagacaata tattgttatt ccatgtctga tataacaggc cggagaagat
    14101 aaatgtcacg gtataaaggc gtggtagtag aaatgaaaga aggtctatac aggccattaa
    14161 tgtaaggaaa gcatagaaaa taatcactat tatagattga atcagtgata gctgatttaa
    14221 tgaaagatac ataacggcaa gcgttgtcag tatcaggcag taatatttct ctgctccggt
    14281 tttataagat acattaagtt tatttaaacg gaatttaact tcattgtagg cgtagcattg
    14341 acagacgata tttgcacagc aaagtatcgc cgtattaaat atgctgttta gcataagtta
    14401 ccttaccatg tatttattgt agacatagcg tgcgtatttg attcttttct gttcgttact
    14461 ttctttgaaa ccagcgttat aactgccaag acaactccag tttatgccgc atttctgaaa
    14521 atgtgttgcc agaatccacg cgccaatctg tatattgaga caggggttat caataagctc
    14581 tgatttgtct tttattacgc caagtttttt caggttaggg atgtgtgatg aattaatttg
    14641 cattagtccg taatcggtgc ttaatatttt tcctttttct ttgttgtgat ttatccggtc
    14701 tggtatgagt gaactttcta cagtggcaat gcttttcaga agcagggggt caatcaggta
    14761 acgttgcccg gcttgtgcaa agcaggcatc aaatcgggtc gttgtcgctg aatatgcggg
    14821 ttgcaatgaa aagattaatg atgaaataca tgatagcagg atataaagaa cagaacgcac
    14881 aatactcctc cttaaacatg gaaaaaataa gcgcccgaag gcgcttatcc gatgcacatg
    14941 aaaaatcagg aatcagtgct gaaggtcagc gtattgctgt cagatgcgca aacagttgct
    15001 gcactgacgg ttgatgtgga agtgttgtta attttggaga ttgcgctgga agaacgcagg
    15061 gcgtttacca ttgccatgca gtttttctgt gggacattgg cctctacaac attgaaggag
    15121 tatttatccg aagaggtggt gattgtaacg gagccgcccc acgggttttt cgcgcttgcg
    15181 ccagttgtat ctgcgatcat atcggatggc agtaatcctt gcgcgtagag agtcttaata
    15241 tagttactgt cagtataacg cccctggaat ttcagtgatt tcatgttggc aatcactgtc
    15301 aggacattgt tttgttcatt ggatgattga atgttggatt gcaccattga atagagttta
    15361 tatgcacttg ctgcaagtac aacaataaca ccaacaacca ataacacttc catcagtgtt
    15421 gcccctttgt cctgttcttt tttacggcgt gcagaaagag aagaaaaaac agaacgcata
    15481 tttaaaatat taatagaaga cataataaat aattccttat ttattgagag gttaaaaata
    15541 ttagggatta gtgttgcagg acgttactga catcgtagag agcagtaatc atcattacaa
    15601 taaatgcgaa aacaattaat gcggatacta cagttatcca gactcctgtt gatttgactt
    15661 ttccttttgc ttcctccagc catttatcag catagttaga catcatcaat gcattgtcag
    15721 cattttcaga atgaagtaat agtttgttaa tgcataattt cgatgggaag tcataaccgc
    15781 aacttttcat tgccattgca agtgactgtc caagtaaaac atatctcctg atttctttta
    15841 ttcgttcgag tagccatctg ttttgagtgc tgtttttctc cagcctttcc agtgcttttg
    15901 caacgggaat atcaatactt aacatggagg ccatgttgaa gagaaaactt acaccattaa
    15961 atgttttata aagtgaccag gggggaatgt aatcaagata ctgacggccc ggtcctgtat
    16021 aacgcgcaag cgaatatctg atcaggaaaa acagtacgat gcagaagcag agaatatacg
    16081 ttccgttttc tatcaggaaa ccagacgtat ctgtcagtaa tcgcatagaa cttgtccagc
    16141 gttctttcgg tgcgagagaa aggaaaacag gtgttatggt atcgtggacc atatacatgt
    16201 ttgccagaca accaaaaacc agtacggatg gataaatcat cgacataaca agagtcattg
    16261 tcatttcaga acgacttctg acaattttta tggcctgaac taaccctccc gcaaggtcgc
    16321 cgcgaatttc accgctggat attaattgat attcatcctc ctttatatat ttttttaatg
    16381 ctgaagatat tgcccctgtg ttattcagtg cattaaggca ctcacaacaa atatagtagg
    16441 ttgcagaaga ccccgttttc ttcccgtagt ctgtttctac atcaatcagg tgtgtaagag
    16501 cacgctttac atttatgcca tcatttaaca ttccagataa atcttcatat aaacttattc
    16561 tggaatacct gaatgtgtat tttgccagcc agtgggatat tccagagaaa tcaatttcta
    16621 tcgaattgag tttctcaaat atatctttta tcgccatgtc ccctccggga gcattgagta
    16681 tttatcttcg tcaatggggg atatgaagtg tgcggacagc ggatctacca ggccatgatt
    16741 aatcaggtgt aataagtgct gattacgggt aattcctcca agttcatagt gccagtatga
    16801 ttttgcttcc agacgcccgg actgacgata taactgaaaa aaacgtgcgt cgggtgagac
    16861 gacttctgct ataaccgttc ttcccgttac gcctttataa cagtgctcgc aaccgtcaag
    16921 attgcgcaac cggacctgtt ccggcaggca attttcctca atgagtttcc gttcttctgt
    16981 actcagtttg tctgccattt cagcataagt gcgcttacag taaggacaga gtttttgtac
    17041 cagccgttga ctcagcagac cgataaacag aagaggatct gcaattagcc tggcctgaat
    17101 attctccatt tcaaggcgct caataatatt cagggcatcg ttggcgtgta aggtcgtcaa
    17161 cagaaggtgg cctgtcatcg aggctttgat tgctgctaat gccgatgcgt gatcacgaat
    17221 ttcgccgttc agtatcgcgt ctggatcaag tcgcatagcg gatttaatcg cgtcaaccca
    17281 gccatcgacg gaatccctga ctgccgtctg tattgcgccg ggaatgcggc cctccggcgg
    17341 tgattcaatg gtgaaaaggc gttttcgggg gagacgcata ttatcgttat ggttgaaacc
    17401 aaacgtgctc agataggctt ctgaagccgt tctcagagtc gttgacttac cggaccctgt
    17461 agggccggat aaaacgataa ttccttccgg gcgttgtaac attcgcctga ttgtctggat
    17521 ttgttgtggc atgtagccaa gttcttcgaa agtgggaata tcctcgctgt catctttaat
    17581 caggcggaag accgcgtaca caccacccac gcacggataa tgcgaatagc gcgccccaaa
    17641 aagatttaca ggcttcagaa aattctctgc gatacgtgca tcctgcggta ttgccgggtc
    17701 aaactgcgta cctttgataa catcgctcat tccagaatag gcagcaccca gcaattccag
    17761 cccttcttta cgcgggatga catccagaat ttccagttcc ccatgcacgc gtgcttcgac
    17821 ataagtgaac tcggaaccgt cccgaccagg tgtgatgtgc aaatcggaac ttcccaggtt
    17881 gtttgctttc gccaggtagc taatgacctt ttcctggttg ctgtttaagt gttgtgatga
    17941 gtttgaatca gaccttcttt cgctgtcctg gtagcgggat gcgataacat caagagtggt
    18001 ccaggttata tttacctttc cgggatattt aacattcaga gtgccaatat aagcctgaac
    18061 agcacgctgt cctttactgt tatcagcgat ataaacatga acaggtttat cgtctttttc
    18121 agatatactg acgtatacaa catcagaaat atcttttccg ggatagtctg cgtcagaaaa
    18181 aaacattatg tgtcgtctct ttcaatagca ttaaagaata agctggcgtt tctctgtacc
    18241 attctgaatc cagacgccat taccggtgat tgatgccacc ttataagaag taccaggaat
    18301 actttgcccg accttgacat cagttactga cccgtccagg agagaaattc gtgctgacat
    18361 ttgttgtggt gtaccaaata tttcaataac acgaagtgat ttagcggcta cacgttgcgc
    18421 tggtatatcg gtatctgcaa gagaagaata cccggaagag ggcgttattg ctggcgttgc
    18481 ggacgctaca ccattcaaat caagattacg caattcactg acagccttct gacgcgccag
    18541 ctttgcttcg taaattaccg tttcagcctg aatctgctct acctgtaaaa tggtcggaga
    18601 tgaatatttt atttcgtctt ttggcgtgct ttcagattct gttgcgtaag caagtgaact
    18661 gaaaaaacag acagaaataa tcgttggttt aattattttt aacatagaat gcacctttaa
    18721 tctcataatt cagtcttcct tcttccagtt ttattcctgc atactggaag cgaacggcag
    18781 gttcatgaaa gttagcgaaa agtattgaag gcggggtgct ggtctgaatc attaattcat
    18841 actcgttcca cgggagaatt attggacggc cttcttcatc tgtttttgtg ttttcaattt
    18901 cctgccaggt gagttttaac ctcatttttt gtgcaaatgt tgtcaggcgt tcctgaatat
    18961 ctgttgcctg tggcaatgtg tccggggtaa ttggatcagg tgaaacgtca aaactgacag
    19021 gaagagaaaa tcccccggcg ctgccttctg gcaatacaaa agttgctgtg gttgtcccct
    19081 ggaatatttc tcgtatccgt gtgctgaagt cctcgaccgt aacgccgctc agttccttat
    19141 atgatgtgcg taacagcccg tcattaccgg atgtgctgca ttcagcaagg tcaaaacgcc
    19201 atccggcgat cgataagggc agtgcatccc atttatcaat gcatttatca ataaatggtt
    19261 ttatttcagg taaatgttgc cacggtgggg caatctgtat tgcctgtttg tctgccattt
    19321 cttttgccag acgaagacgt gcagcttctg ccgcagcttc tttttcccgg tattcctggt
    19381 acatggtgat cccgttccag agcagtatgg ccagaatggc acttccgcca taaatcatga
    19441 actgacgttt tcgggatacg cgagtaaacg ccgcctcttt cggcggtttt tttacgtcaa
    19501 tcaacgcaga cagagtgagt gaggggagtg cctggctgat atcccatgat tcaggctggt
    19561 atagtttcca gccgggttct ggtgtttcat taaactcaag aaatgttgtc agagcactca
    19621 tgatctgact tttgttacct acaacatcgt tgacgagaac gttattgacg caggaaacaa
    19681 agccataaag atcaccgagt tcgcagatag cgtatccgtc aggttcgatg aggggtttta
    19741 tcatcagtgc cagtgaccag aatgaggacg cccctgtggg aagatcctct tttctgataa
    19801 atgccaccat cgttttggtt tcattttctg aatcctgata ctgacaggag agaaaatatt
    19861 cagcgtcgtt ttttcttgcg aatgtacgcg cattcttttc ttctgaagga agcgttttcc
    19921 agtccagacc ggagaaaaaa gcacgcttgt ttttaataac cgaagtgaaa ttccggttat
    19981 tctgattatt ctcagacaaa gtgacctcca aaaaaactcc ctgtgttttt tcagggagtt
    20041 ttcagttaat tagttcacat tttttattac tgcactggag ccggaattaa gcacatttgg
    20101 tgtaatcaaa acgaccagaa tcgtgtcgcc gtcttcgctg ttaatgccac ccccaagtcc
    20161 aaagaaggag ggggttatta caccttgctt actggttttc cggtttgatt gctggaatcc
    20221 actcagaata actgtctggc ctgatttcag gtcaatagtc tgattaattg ttttcaaatc
    20281 cacattcggt gtttgtgctt tactgccgcc actttcgaac acctcaaaag taggtttgtc
    20341 agacagactc attgagaaca gcaattgcag gttttgtgaa tccggctgaa tgtatggaag
    20401 cagagtcata ttgaatccgg tcgttattgt tgccgcattc agtgacgtgg atgatcccac
    20461 attggcggtg gaatcggttg tgacactttc aatgaagccc tgctgattgg caatttgcat
    20521 agggacgggc gtcaggtttt tagtcacagc ggagttttgc gttacgacac tgacgctgcc
    20581 ttgtgacgac agggctttca gaaatgcttt tgagccagcc agcttaccgt ccacgatgga
    20641 tacaccactg gtaataacat tctcggcggc attaccaaat gagccaccaa gactcagacc
    20701 aagatgacca tcattaaata ctgcgttcca gtcgattccc gcctgttcct ggcttgattt
    20761 cttgatactc aggatttcaa cgttcagcac aacctgacga ctcatttcat tattgcgctt
    20821 gttcacaatc tcctgaacgc tgtccagtac atccggggta tctgttactg tcagtgaacc
    20881 agtggacaga tacatgcgcc ctgtgcctgg tgtcagcatt gaggaaactt cgcttttcag
    20941 gtcgttgtac agcgatgatt tcatttccac ggttgtagtt tgcgtatttg atgcgtcgcc
    21001 agtcataccg ccagagctgg tagagccggt actgccgctg gaagacattg tgccgctcac
    21061 aacttttgag ttgtatgcca cattgctgtc catatatgtg atcgggaatg agcgcgtttc
    21121 cagatagaag aatgtgatac gacctttatc gtatttccag gatattccca gccgtgagga
    21181 tacggtttgc agtagggcag gaagcccgga gatattcagt tccgggagtg atgtaccgcc
    21241 agaagagact tttactggct gactgcctac tgacgccaga ggaaccattc catttgcatc
    21301 cggtgctgga attgatcctg tcatttgttg tgttgagcca gtgcctgtac cgttcagata
    21361 ggtccagaca tcggcgctga ttcgtaccgg gatatgacag gtttgtgtga tgcgttgtgc
    21421 gatctggcgt agctcaatat ctgaacgagt attaatcaca atcgggcagg gcggcgctga
    21481 ttgctttacc tgcttttcaa taattggcgt tgtattaatc cattgttttg ttgagtcctg
    21541 gataaccggg ttattacgaa tttttttcgc gtattcagtc gctttttgtg cgtctttttc
    21601 ggctgcaagt tcattagtat tgattttttt gaagtttgca cagcctgata ataaaaaaga
    21661 ggatattaat aaacaaagca attttttatt catatttaat taactccggt actggaatga
    21721 taactgtgca tcctatttca tcgtgagagc gggttaacga tataactgtg tcgaaaaggt
    21781 tttgtatctg cacgccgcca tctgaaggag tcgtgacaac aataagacgt ttgccacgtt
    21841 tcctggctgt tttaataaat cgaacaataa actgaacaac ttttgattcc cgtaagttgt
    21901 taccgatggc tacactatta agaaccaacg ttttttcagg tgcagataaa aagtcaaaat
    21961 aatcaaaatt ttcatcgcaa agataatggt gttttagaag gggaaggtgt tcatggcgtt
    22021 tataaatatc acagaaatca aaatatttaa cgtcagtgtc attgattagc aattctgcta
    22081 aaagtgttga ttttccagtt ccagtttcgc ctataatcag aatatgtttt tcagagttta
    22141 tcaaaacatc aatggcttct ttcatcatat tcatattcat attcatattt atcatattcg
    22201 agtgttttat tctcataata gaatcctgtc tttgctaatc aatagtatct ttattgcgag
    22261 gattattcag atacgtctgt tttatcgtga ttatcaaggt ctggattagt aatcacattg
    22321 cctccggcaa ccatgacttt ttttcctcca gctttaggga gataaatttc tgcaattttt
    22381 gctatttcat ccatgacttc ttgtgtaaac aggtttggaa tgtcaacatg attgttacgg
    22441 gcgatatcca cgcggcgttt aaactctggt tcttcaaacc agattatttt gttggcaata
    22501 aatggtcggc taaattcact ggttataatt tcacggattg caatatttct ggctttattc
    22561 ttcttatccc ggagagacac aatttcttca ggaagaagaa ccgggcgctc tattacatca
    22621 tcattccgtg tacgtgaact tcctccctta ccaccaccac tggatattga gcgtttggat
    22681 attttcatat cacgcacccc aatctcttct gaaatctttt tagccagagc attttttgat
    22741 ttcggcggat agtaaagcac aacagcactg ttttcagtga atgtggtcca tccttcctga
    22801 ccgtacatat cgcttttttg cccttgtcct tcattctgaa gaatgaacat aaagcgaagg
    22861 ttataacctg ctgtaaaacc aacagcgcgt tcaatgacct ccgatttacc cattgatgta
    22921 aattcatcca ggagaataag gcactggtat ttcaggtccg ggttatgttc cggcagttca
    22981 cgacagtttt cattaaccag taatgagaag aaaaggttta caattttctc atgagtgatt
    23041 aaggcatccg gtgtcagacc aagataaatt gacatgggtt ttttacgaat atcccggata
    23101 tcaaaatcac tgaaattcgt cgcttcagca gtaacagggt tgctgaatat attcagtggt
    23161 gatgaaaagt tcgtttttat acttcccctt gtgcgatctg gtgctgacat gaactcaaag
    23221 aagaatgatt ttgttttatc gctaatccag ctacgatttt caacttcctg tcccatccat
    23281 gcggcgagat cttttccatt atcgggaatc gacgttttca gtatggcgct gatggaaaca
    23341 aggacgtccg gtgcattatg acctttggct ttctggtcca ggtgaaaacg ctccttgtcc
    23401 agcaggtaaa gccctaaccc gacaaaaagg ttgcgtgcag aatcagacca tataggatca
    23461 tcacttgccg ggataaggat tgcggcaatt tttgccaggt ccgtttcacg aagtaaatca
    23521 ctgcgactga cgcaatccag aggattccag cggtgagagc gtatctgtcc tttaattgcc
    23581 tggtcgatag tttccgcgta tccggcgggc gcaaagagaa agcatttttg ccctaattct
    23641 ttttgcctga atccggctga taaaaaccag ttttcaagtt tgatatccag tatgaccata
    23701 cttcctggat agtttacgca gttggggata acaatcccca cccctttacc agaacgtgtc
    23761 ggggcataaa gaattaaaaa ttgttgtccg gcgaaataaa taaattgttt tttgtatctc
    23821 cccttgaaca ttttaccgat gagtattggt ggatgtttgt aaggtgattt tttatccggg
    23881 aaaaaacctg atttactcag gtccatatca gttgcgagcc gggcgtcacc gtagatgact
    23941 tttttaggca taatcccaat cacgacaatt aacatgaata tggcaaagaa tattaatgga
    24001 acgctgaatc caaaccatgc cataaaaacg agttttttat attgtgggtt gccagaaaat
    24061 gttgagatta cagaatggaa tgtatcccac ttgagcaaag acatatcaac ggatgaatat
    24121 cttaatgctg tgtatccacc gagatagttt gaggctataa gcacacccac aagaagcagt
    24181 aacaggaaga gaattaaccc ccccatcttt tttgcattca tagttatctc cacaatttac
    24241 attgtgctca aaaaacgatt tttttcttcg ggttcgtaat acagttcagt cattctggta
    24301 tggttgaaaa aaagaatgac atcaattgat gtttttatcg tgcgcatgat gaggtccata
    24361 tcaacagtca taccaacatc agattgtttt acaatacttg ccagtcgtga aaatgaggca
    24421 taagtattat tagcatgaat ggtactgatt gagccttcat gccctgtatt aagcgcctcc
    24481 agataactcc atgcttcgtt acccctaagt tcagcaagaa agatgtgatc tggctttaat
    24541 cgcatacacg cttcaatgat ttccttcgct tcaacggtat tttttttgta gaaaagccgg
    24601 atgtggtttg gatgcagcgg cagagacatt tccggtacat cttcaacggt tatataacgc
    24661 cgttcaggtg gaaagatatc tgcaattgcc tttgctatag ttgtcttacc ggagccagtc
    24721 ccacctacga ttaaaaaatt aagacggtct ttaactgcct ctcttaaaaa ttgagcttta
    24781 gattgaccat ccggacgccg ggataattca tacaggtagc gttgccgttc agtcagtatt
    24841 gcttcgtgtt ttgttgcaat cctgacatta tcaaaacgcc ctgttcggac ataatcatct
    24901 atagtgaagc gtgttaatga tggcttgcgg atagatatca caacgctgtt attttccgtt
    24961 gcaggtggaa tgatgatttg tccacgttcc ccaccgggaa gaactaccga tgcaatggga
    25021 ttatcatggc taagtggtat ttttatcttt gataagttcg tcagagtttt ggcaagtgtc
    25081 attaaattat caaaagtcgc gtctggcgca tctttagatt cccagccatt tttcccttca
    25141 aaccatattg ttcctggttt attcacagat atttctgtga catgttcaat attaagaaca
    25201 gactggatac ccgtcatatc cagatatcgt cttgcggttt tactgttatc tcgtggttgt
    25261 gatgtattac tggtatctct gatgttattc atatcaattg ctttactgaa ttactgaagt
    25321 tcatatacgg atgaaaagtc gatatttcgc ggaacaataa cagacaatac agtcccctga
    25381 ttaatatatg ccgtgggggg aatatttatc gtattgtcca gcgttgtttt tgccatttct
    25441 tttgttgcgt cagatgtgtt ttcgtaggtg atattgctgt ttgagcctgt ttgttgcgtg
    25501 ctgtttttca gaatatctaa accatcacca agtaatgaca gcagcaatgc accaccaaaa
    25561 cgctgaccaa aatgattatc gacccatgca ggaaggccgg aagcgcccag actgtcagtg
    25621 ccaagtgcgc caatgcgcac attgacattt tcatctttga gcgttgtcca gttaacgaac
    25681 acacgggcta ctccctgtgt catgacttta ttctgctccc cgatcagtaa tgctccttta
    25741 cgggcaagaa gcacttcgcc gttatccgac cagacgtctc gtgttaactg acacattgtg
    25801 ataccgggat aagaggttac gattttcgtt ttgagcacac aggataatgc tgttcccgca
    25861 gataacagat atcggcggtt cagcacaggg gatacctttc cgtctgcgta ctgactgccc
    25921 tgtaaatcat ctctttcctg gtttttttcg cctggttcct gattgtcgat cttcaccatt
    25981 gtgtcgccca tcagttgtcg gacggatttt ggcaatggtt gtggttggtt tggatctcca
    26041 ctggcggttt ggggactgcc gttggctatc acattgacgg ctgtttgatc ggccttttgt
    26101 gatgctggcg ctgacggggc attgtctgcc tgtttctgtt cttgctcctc ctgtgctttc
    26161 ctgcggttag cggcatcgag tttttccttt tcttcgatgt ttttcatcat tgttgtcagt
    26221 gaaacgccat tgttggtatt tgtgaccagt gtctcgtcag acttctcaag aggtgtttgc
    26281 tgaacgacct gttctcgtga aagaacttta aacaagataa tgatcacaaa taacgcggca
    26341 atcagtaata tgatgaggat taatattttt tttggtgctg ctttaccttt tacttcgata
    26401 attccgcgat ttcccgcgtc attatttttt tcatcatctt tatttttcat agctgaactt
    26461 ctctactcgt gtttttccgt ttgacgtacc ttttttattc cacggacgat taacgattga
    26521 tgatgttctg atatctgcaa cctgatcacc caggcgcaaa cggagatttt cagccacgtc
    26581 atagtaaacc attgtgtttt tatttctgtc tccgttaacc agatgttcat ttccatcggc
    26641 atcaacacga taaaggaccg gaatttcctg tttattagtc catctcatgc atgtaaattc
    26701 gccattatcc catacctgat aagggaaaat tgatttgtcc cccttgagtt gataatgacc
    26761 attaattatt ccaccatcag tgcatggaaa tggcttttca gtcattacgg tagctgacgg
    26821 tggtttcgga taattaaaac gcagaatata cgtgggttgt ttcgtggttg atatcaggta
    26881 aagaggatat atatgcttat tggtctgaac ggtaacgttt gtatccggtt cttctgcttt
    26941 tggacgcaga aacagagtgt tgtccctgac cgatactgac caggcttctg gatcaccaat
    27001 tccgacatct tttattgttt cgtcttgtcc gaacttaatt gttgtttgtg cgcctgcttt
    27061 tacgcgcaca ttaaatacat cctgctcgtt ataatctacg gtctgaatac gcccgtctcg
    27121 ttccgatggt gtgccgtaca tagctgctaa agcaccaggt acttgtagca tcgacaaaag
    27181 aactatcgca gtagtgcgtt taagcatcat tttataacct ctggatcagg ttggtagctc
    27241 agaacttgca gtcccagcgg attcacaagg cgctcttttt ct
//
