LOCUS       NZ_CP069921             9515 bp    DNA     linear   CON 03-DEC-2023
DEFINITION  Klebsiella oxytoca strain FDAARGOS_1334 plasmid unnamed10.
ACCESSION   NZ_CP069921
VERSION     NZ_CP069921.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN16357476
            Assembly: GCF_016903415.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella oxytoca
  ORGANISM  Klebsiella oxytoca
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 9515)
  AUTHORS   Sokurenko,E., Tallon,L., Sadzewicz,L., Zhao,X., Boylan,J., Ott,S.,
            Bowen,H., Vavikolanu,K., Mehta,A., Aluvathingal,J., Nadendla,S.,
            Yan,Y. and Sichtig,H.
  TITLE     FDA dAtabase for Regulatory Grade micrObial Sequences (FDA-ARGOS):
            Supporting development and validation of Infectious Disease Dx tests
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9515)
  AUTHORS   Sokurenko,E., Tallon,L., Sadzewicz,L., Zhao,X., Boylan,J., Ott,S.,
            Bowen,H., Vavikolanu,K., Mehta,A., Aluvathingal,J., Nadendla,S.,
            Yan,Y. and Sichtig,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-FEB-2021) Institute for Genome Sciences, University of
            Maryland School of Medicine, BioPark II, 801 W. Baltimore St., Suite
            619, Baltimore, MD 21201, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. 1.8
            Genome Coverage                   :: 591.2x
            Sequencing Technology             :: Pacbio; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 12/03/2023 03:56:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,915
            CDSs (total)                      :: 5,798
            Genes (coding)                    :: 5,689
            CDSs (with protein)               :: 5,689
            Genes (RNA)                       :: 117
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 47 of 109
            Pseudo Genes (incomplete)         :: 70 of 109
            Pseudo Genes (internal stop)      :: 26 of 109
            Pseudo Genes (multiple problems)  :: 29 of 109
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP069921.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..9515
                     /organism="Klebsiella oxytoca"
                     /mol_type="genomic DNA"
                     /strain="FDAARGOS_1334"
                     /host="Homo sapiens"
                     /culture_collection="FDA:FDAARGOS_1334"
                     /db_xref="taxon:571"
                     /plasmid="unnamed10"
                     /geo_loc_name="USA: WA"
                     /collected_by="ARMADA"
     gene            80..385
                     /locus_tag="I6K64_RS28690"
                     /old_locus_tag="I6K64_28685"
     CDS             80..385
                     /locus_tag="I6K64_RS28690"
                     /old_locus_tag="I6K64_28685"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_225089217.1"
                     /translation="MAVAVAGDHPAAVQVTMTLVNDTGFDPVFSGSIAESWRQQPCTPS
                     YCCDWEAATMLRAFPLAKKGEGRARLPSLYASFGKLGETPTHEDIIDNNRSINWPV"
                     /name="hypothetical protein"
     gene            complement(942..1709)
                     /gene="fecE"
                     /locus_tag="I6K64_RS28695"
                     /old_locus_tag="I6K64_28690"
     CDS             complement(942..1709)
                     /gene="fecE"
                     /locus_tag="I6K64_RS28695"
                     /old_locus_tag="I6K64_28690"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418707.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate ABC transporter ATP-binding
                     protein FecE"
                     /protein_id="WP_000175457.1"
                     /translation="MTLRTENLTVSYGTDKVLNDVSLSLPTGKITALIGPNGCGKSTLL
                     NCFSRLLMPQSGTVFLGDNPINMLSSRQLARRLSLLPQHHLTPEGITVQELVSYGRNPW
                     LSLWGRLSAEDNARVNVAMNQTRINHLAVRRLTELSGGQRQRAFLAMVLAQNTPVVLLD
                     EPTTYLDINHQVDLMRLMGELRTQGKTVVAVLHDLNQASRYCDQLVVMANGHVMAQGTP
                     EEVMTPGLLRTVFSVEAEIHPEPVSGRPMCLMR"
                     /name="fecE"
     gene            complement(1710..2666)
                     /gene="fecD"
                     /locus_tag="I6K64_RS28700"
                     /old_locus_tag="I6K64_28695"
     CDS             complement(1710..2666)
                     /gene="fecD"
                     /locus_tag="I6K64_RS28700"
                     /old_locus_tag="I6K64_28695"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate ABC transporter permease subunit
                     FecD"
                     /protein_id="WP_000684856.1"
                     /translation="MKIALVIFITLALAGCALLSLHMGVIPVPWRALLTDWQAGREHYY
                     VLMEYRLPRLLLALFVGAALAVAGVLIQGIVRNPLASPDILGVNHAASLASVGALLLMP
                     SLPVMVLPLLAFAGGMAGLILLKMLAKTHQPMKLALTGVALSACWASLTDYLMLSRPQD
                     VNNALLWLTGSLWGRDWSFVKIAIPLMILFLPLSLSFCRDLDLLALGDARATTLGVSVP
                     HTRFWALLLAVAMTSTGVAACGPISFIGLVVPHMMRSITGGRHRRLLPVSALTGALLLV
                     VADLLARIIHPPLELPVGVLTAIIGAPWFVWLLVRMR"
                     /name="fecD"
     gene            complement(2663..3661)
                     /gene="fecC"
                     /locus_tag="I6K64_RS28705"
                     /old_locus_tag="I6K64_28700"
     CDS             complement(2663..3661)
                     /gene="fecC"
                     /locus_tag="I6K64_RS28705"
                     /old_locus_tag="I6K64_28700"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dicitrate ABC transporter permease FecC"
                     /protein_id="WP_000125187.1"
                     /translation="MTAIKHPVLLWGLPVAALIIIFWLSLFCYSAIPVSGADATRALLP
                     GHTPTLPEALVQNLRLPRSLVAVLIGASLALAGTLLQTLTHNPMASPSLLGINSGAALA
                     MALTSALSPTPIAGYSLSFIAACGGGVSWLLVMTAGGGFRHTHDRNKLILAGIALSAFC
                     MGLTRITLLLAEDHAYGIFYWLAGGVSHARWQDVWQLLPVVVTAVPVVLLLANQLNLLN
                     LSDSTAHTLGVNLTRLRLVINMLVLLLVGACVSVAGPVAFIGLLVPHLARFWAGFDQRN
                     VLPVSMLLGATLMLLADVLARALAFPGDLPAGAVLALIGSPCFVWLVRRRG"
                     /name="fecC"
     gene            complement(3658..4560)
                     /gene="fecB"
                     /locus_tag="I6K64_RS28710"
                     /old_locus_tag="I6K64_28705"
     CDS             complement(3658..4560)
                     /gene="fecB"
                     /locus_tag="I6K64_RS28710"
                     /old_locus_tag="I6K64_28705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418710.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate ABC transporter
                     substrate-binding protein FecB"
                     /protein_id="WP_000879164.1"
                     /translation="MLAFIRFVFAGLLLVISHAFAATVQDEHGTFTLEKTPQRIVVLEL
                     SFADALAAVDVSPIGIADDNDAKRILPEVRAHLKPWQSVGTRAQPSLEAIAALKPDLII
                     ADSSRHAGVYIALQQIAPVLLLKSRNETYAENLQSAAIIGEMVGKKREMQARLEQHKER
                     MAQWASQLPKGTRVAFGTSREQQFNLHTQETWTGSVLASLGLNVPAAMAGASMPSIGLE
                     QLLAVNPAWLLVAHYREESIVKRWQQDPLWQMLTAAQKQQVASVDSNTWARMRGIFAAE
                     RIAADTVKIFHHQPLTVVK"
                     /name="fecB"
     gene            complement(4605..6929)
                     /gene="fecA"
                     /locus_tag="I6K64_RS28715"
                     /old_locus_tag="I6K64_28710"
     CDS             complement(4605..6929)
                     /gene="fecA"
                     /locus_tag="I6K64_RS28715"
                     /old_locus_tag="I6K64_28710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent Fe(3+) dicitrate receptor FecA"
                     /protein_id="WP_000188262.1"
                     /translation="MTPLRVFRKTTPLVNAIRLSLLPLAGLSFSAFAAQVNIAPGSLDK
                     ALNQYAAHSGFTLSVDASLTRGKQSNGLHGDYDVESGLQQLLDGSGLQVKPLGNNSWTL
                     EPAPAPKEDALTVVGDWLGDARENDVFEHAGARDVIRREDFAKTGATTMREVLNRIPGV
                     SAPENNGTGSHDLAMNFGIRGLNPRLTSRSTVLMDGIPVPFAPYGQPQLSLAPVSLGNM
                     DAIDVVRGGGAVRYGPQSVGGVVNFVTRAIPQDFGIEAGVEGQLSPTSSQNNPKETHNL
                     MVGGTADNGFGTALLYSGTRGSDWREHSATRIDDLMLKSKYAPDEVHTFNSLLQYYDGE
                     ADMPGGLSRADYDADRWQSTRPYDRFWGRRKLASLGYQFQPDSQHKFNIQGFYTQTLRS
                     GYLEQGKRITLSPRNYWVRGIEPRYSQIFMIGPSAHEVGVGYRYVNESTHEMRYYTATS
                     SGQLPSGSSPYDRDTRSGTEAHAWYLDDKIDIGNWTITPGMRFEHIESYQNNAITGTHE
                     EVSYNAPLPALNVLYHLTDSWNLYANTEGSFGTVQYSQIGKAVQSGNVEPEKARTWELG
                     TRYDDGALTAEMGLFLINFNNQYDSNQTNDTVTARGKTRHTGLETQARYDLGTLTPTLD
                     NVSIYASYAYVNAEIREKGDTYGNLVPFSPKHKGTLGVDYKPGNWTFNLNSDFQSSQFA
                     DNANTVKESADGSTGRIPGFMLWGARVAYDFGPQMADLNLAFGVKNIFDQDYFIRSYDD
                     NNKGIYAGQPRTLYMQGSLKF"
                     /name="fecA"
     gene            complement(7016..7969)
                     /gene="fecR"
                     /locus_tag="I6K64_RS28720"
                     /old_locus_tag="I6K64_28715"
     CDS             complement(7016..7969)
                     /gene="fecR"
                     /locus_tag="I6K64_RS28720"
                     /old_locus_tag="I6K64_28715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric citrate uptake sigma factor regulator
                     FecR"
                     /protein_id="WP_001068910.1"
                     /translation="MNPLLTDSRRQALRSASHWYAVLSGERVSPQQEARWQQWYEQDQD
                     NQWAWQQVENLRNQLGGVPGDVASRALHDTRLTRRHVMKGLLLLLGAGGGWQLWQSETG
                     EGLRADYRTAKGTVSRQQLEDGSLLTLNTQSAADVRFDAHQRTVRLWYGEIAITTAKDA
                     LQRPFRVLTRQGQLTALGTEFTVRQQDNFTQLDVQQHAVEVLLASAPAQKRIVNAGESL
                     QFSASEFGAVKPLDDESTSWTKDILSFSDKPLGEVIATLTRYRNGVLRCDPAVAGLRLS
                     GTFPLKNTDAILNVIAQTLPVKIQSITRYWINISPL"
                     /name="fecR"
     gene            complement(7966..8487)
                     /gene="fecI"
                     /locus_tag="I6K64_RS28725"
                     /old_locus_tag="I6K64_28720"
     CDS             complement(7966..8487)
                     /gene="fecI"
                     /locus_tag="I6K64_RS28725"
                     /old_locus_tag="I6K64_28720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor FecI"
                     /protein_id="WP_001283626.1"
                     /translation="MSDRATTTASLTFESLYGTHHGWLKSWLTRKLQSAFDADDIAQDT
                     FLRVMVSETLSTIRDPRSFLCTIAKRVMVDLFRRNALEKAYLEMLALMPEGGAPSPEER
                     ESQLETLQLLDSMLDGLNGKTREAFLLSQLDGLTYSEIAHKLGVSISSVKKYVAKAVEH
                     CLLFRLEYGL"
                     /name="fecI"
     gene            8624..8692
                     /gene="ykiE"
                     /locus_tag="I6K64_RS29670"
     CDS             8624..8692
                     /gene="ykiE"
                     /locus_tag="I6K64_RS29670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_010051215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YkiE"
                     /protein_id="WP_211180522.1"
                     /translation="MGWSLCFWHVSVRMTHDVVCYY"
                     /name="ykiE"
     gene            8779..9467
                     /locus_tag="I6K64_RS28730"
                     /old_locus_tag="I6K64_28725"
                     /pseudo=""
     CDS             8779..9467
                     /locus_tag="I6K64_RS28730"
                     /old_locus_tag="I6K64_28725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558153.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /name="IS1 family transposase"
ORIGIN
        1 aaccgagact ggaaaaacgc taacgcggag gccagtgtta gttgaccaca acagactacc
       61 tgaagggagc cgcggtcgcg tggcagttgc agtagcagga gatcatccag ccgcagtaca
      121 ggtcacgatg actctggtta atgataccgg ctttgacccc gtattttccg gctctatcgc
      181 tgaatcatgg cgtcagcagc cgtgcacacc atcctattgt tgtgactggg aggctgccac
      241 catgcttcgc gctttccctc tggcgaaaaa gggagaagga cgggcccgtc tgccttcact
      301 ttatgccagc ttcggtaagc tgggtgagac accgactcat gaagatatca ttgataacaa
      361 tcgatccatc aactggcctg tataacgtgg ctgccggtga ttaagaaagc tgcacctacc
      421 taagtagtag caaacgcaca ctttttagaa aaatcgatgg tcagaaactg gattagcaat
      481 tccgttccag ggttgctttt gatttacgtt ggcgtctgat cattgattta tcctcaaaag
      541 cccaacctca ttggtaatga accagctccg tgaatgtccg ctctggcaca gagcgaaatt
      601 ttttgatctc ccccctgaaa tctaaactta gtcatgtcac gtttttgggt ttctaaaatt
      661 ttaacttcgc gtttttcgtt gccgtaaggg ttatacagaa atgtccgtta agcagagttc
      721 aaaattgatt gccgtgatca cgactggttt gaaagccgcg cccaagcctg tacagctctg
      781 gtttgcgttg attatgaacc tgtcagccta aagcaagcgg atggacgatg agtattggta
      841 atctttcaga gtccggaaaa gttcagcccc agtctgaaca ggcttgctgg cgccagtcca
      901 gtttcattca gtcgtggttt ggttcttacg gcctgtgcaa tctacctcat taggcacatc
      961 ggcctgccag ataccggctc ggggtgtatt tccgcttcca cgctgaatac tgttctcagc
     1021 aatcctgggg tcatcacctc ttctggtgtg ccttgcgcca taacatgtcc gtttgccatt
     1081 accaccagtt gatcgcagta ccggctagcc tgattaaggt cgtgcagcac agcgaccacc
     1141 gttttcccct gagtccggag ttcgcccatc aaccgcatca ggtccacctg gtgattgata
     1201 tcaagatagg tggttggctc atcaagtaat acaacgggcg tattctgggc caggaccatt
     1261 gccagaaatg cgcgctggcg ctgaccgccg gaaagctcgg ttaaccgacg aacggcaaga
     1321 tgattgatcc gggtctggtt catggcgaca ttaactcgtg cattgtcttc agcggagaga
     1381 cgcccccaga gtgacagcca gggattacga ccatacgaaa ccagctcctg gactgtgatc
     1441 ccctctggcg ttaaatggtg ctgaggcagc agcgaaagcc tgcgggccaa ctggcgcgat
     1501 gagagcatat ttatgggatt atcgccgaga aatacggtgc cagactgcgg cattaaaagc
     1561 cgcgaaaaac agtttaacag cgtcgatttc ccgcaaccgt tagggccgat cagggcggtg
     1621 atcttccccg ttggcagtga gagtgaaacg tcgttaagta ccttgtctgt cccgtaactg
     1681 accgtcagat tttcagttcg taaagtcatt tatcgcattc tcacaagcaa ccagacaaac
     1741 cacggcgcac cgataatggc ggtcagcacg ccaaccggga gctccagtgg gggatgaata
     1801 attctcgcca gcagatcggc aaccaccaac agcaacgcac ctgtcagggc cgaaacaggc
     1861 agcagtctgc ggtgacgtcc accggtgatg ctacgcatca tatgcggcac cacgagacca
     1921 ataaagctaa tcgggccgca ggcggccacg ccggtagatg tcatggcgac agctagtaac
     1981 aaagcccaga atcgggtatg gggcaccgac acaccgagcg tggtggcgcg cgcatcgccg
     2041 agtgcaagga ggtcgagatc gcggcaaaaa ctcaggctca gcggcagaaa taaaatcatc
     2101 agcgggatgg caatcttcac aaagctccag tcacggcccc ataagctgcc ggtcagccac
     2161 agcagggcgt tgttcacatc ctgcgggcgc gagagcatca gataatccgt caggctggcc
     2221 cagcatgcag aaagcgccac gccggtgagc gccagcttca tcggctggtg ggtctttgcc
     2281 agcatcttca gcaatatcaa ccccgccatg ccgcccgcaa aggccagcag cggcagcacc
     2341 atcacgggca gtgacggcat aagaagtaga gcccccacag aggccaggct ggcggcatgg
     2401 ttaacaccga gaatatccgg tgatgccaga gggttgcgca caatcccctg tatcagcacg
     2461 cccgccacgg cgagggctgc accgacaaac agtgccagca gcaagcgcgg cagtcggtac
     2521 tccatcaata cataataatg ctcgcgtccg gcctgccagt cggtcagcag cgcgcgccac
     2581 ggcacgggga tcactcccat atggagtgat aacagcgcac agcccgccag ggcaagggtg
     2641 atgaaaataa ccagcgcaat tttcatcctc gcctcctcac aagccagaca aagcaagggc
     2701 tgccaatcag cgccagcact gcgcctgcgg gcagatctcc ggggaaggcc agtgcgcgtg
     2761 cgagtacatc tgccagcagc atcagcgtgg cccccagcag catgctcact ggcagtacgt
     2821 tgcgctgatc gaagcctgcc cagaagcgcg ccagatgtgg caccagcaga ccgataaacg
     2881 ccaccggacc tgccacgctg acgcacgcac caaccagaag cagcactaac atattgatga
     2941 ccaaacgtag cctcgtcagg ttcactccca gcgtatgggc ggtgctgtcg ctgaggttga
     3001 gcaggttcag ttgattcgcc agcagcaaca cgacagggac tgcagtgacc accaccggca
     3061 agagctgcca gacatcctgc cagcgggcgt gggacactcc gcctgccagc cagtaaaaga
     3121 tgccgtaagc atgatcttcg gccagcagca gggtgatgcg ggtaaggccc atacaaaagg
     3181 ccgacagcgc gatacccgcg aggatcagtt tgtttctgtc atgggtatga cgaaatccgc
     3241 ctcctgcggt catgaccagc agccagctca cgccgccccc gcatgccgcg atgaacgaca
     3301 gagaatagcc tgcaatcggc gtcggactca gcgcgctggt aagcgccata gccagcgccg
     3361 cgccgctgtt aatgccgagc agtgaaggag aggccattgg gttgtgggtc agggtttgca
     3421 gcagcgtgcc cgcgagcgcc aggcttgcgc cgatcagaac ggcgaccagg cttcgtggca
     3481 aacgaaggtt ttgcaccagc gcttctggta gcgttggcgt gtgtccaggc agcagggcgc
     3541 gggttgcatc tgctccggaa acaggaatgg ccgagtagca aaacagactc agccagaaaa
     3601 taataataag tgctgcaacg ggaagccccc acagcagcac cgggtgtttt atcgcggtca
     3661 tttcacaacg gtaagcggct gatggtggaa gatttttacc gtgtcagcgg caatacgctc
     3721 tgcagcaaaa ataccgcgca tccgcgccca ggtgttactg tcgaccgaag caacctgctg
     3781 cttctgcgcg gcggttaaca tctgccagag cggatcttgt tgccagcgtt taacaatgct
     3841 ctcttcgcga tagtgggcaa ccagcagcca ggcaggattg accgccagca gttgctccag
     3901 gccgatggac ggcatggacg cacccgccat cgcagcggga acgttcagcc ccagagaggc
     3961 cagcacgctg ccggtccagg tctcctgagt atgcaggttg aattgctgtt cgcgtgatgt
     4021 gccaaaggcc acgcgtgtcc ctttgggaag ctggctggcc cactgcgcca tcctctcttt
     4081 atgttgttcc aggcgtgcct gcatctctcg ctttttaccc accatttcgc cgatgatagc
     4141 cgcagattgc aaattttcag cgtaggtttc gttgcgggac ttaagcagca gtaccggcgc
     4201 gatttgctgc aaggcgatgt aaacccccgc atggcgactg ctgtcggcaa tgatcaggtc
     4261 tggtttcaga gcggcaatgg cttccaggct cggctgcgcg cgcgttccga cggactgcca
     4321 cggtttcagg tgcgcacgca cttcgggcag gatgcgtttt gcatcgttat cgtcggcaat
     4381 accgatcggg ctgacgtcca cggcggccag cgcatcggcg aacgagagtt ccagcaccac
     4441 aatccgttgt ggcgtttttt cgagtgtaaa cgtgccgtgt tcgtcctgaa ccgtggcggc
     4501 aaaggcgtgg ctgatcacca gcagcaggcc tgcaaaaaca aaacggataa atgccaacat
     4561 aatcacattc cagctaaaag cccggcaagc cgggcgttaa cacatcagaa cttcaacgac
     4621 ccctgcatat acagcgtgcg cggctggcct gcatagatgc ctttgttgtt gtcgtcataa
     4681 gagcggatga agtagtcctg gtcgaagatg tttttcacac cgaatgccag gttcagatct
     4741 gccatctgcg ggccaaagtc atacgccacg cgtgcgcccc agagcatgaa gccgggaatg
     4801 cggccggtac tgccgtcggc gctctctttc accgtattgg cgttatccgc aaactggctg
     4861 gactggaaat cgctgttcag attgaacgtc cagtttcctg gcttgtagtc cacgcccagc
     4921 gtgcctttat gtttcgggga gaatggtacc agattgccgt aggtgtcgcc tttctcgcgg
     4981 atttccgcgt tcacatacgc atagctggcg tagatggaaa cgttatcaag cgttggcgtt
     5041 agcgtaccca gatcgtaacg tgcctgcgtt tccagcccgg tatggcgcgt tttgccacgt
     5101 gcagtgacgg tgtcgttggt ctggttggag tcgtactgat tgttaaagtt aatcaggaac
     5161 agccccattt ccgccgtcag cgcgccgtcg tcgtagcggg taccgagttc ccaggttcgc
     5221 gctttttccg gttccacatt gccgctttgc acagccttgc caatctggct gtactgtacg
     5281 gtgccgaacg agccttcagt gtttgcataa agattccagc tgtcagtcag gtgatagagc
     5341 acgttcaacg ccggaagcgg tgcgttatag ctcacttctt cgtgcgtgcc tgtgatggcg
     5401 ttgttctggt atgactcgat atgttcgaaa cgcatacccg gcgtgatggt ccagttgccg
     5461 atgtcgattt tgtcatccag ataccaggcg tgcgcctcgg tgccggaacg cgtatcgcgg
     5521 tcgtaagggc ttgagccgga cggcaactgc ccgctgctgg tggcggtgta gtaacgcatt
     5581 tcatgcgttg attcattcac atagcgatag cccacgccca cttcgtgcgc ggaagggccg
     5641 atcataaaga tctggctgta gcgtggctca ataccgcgca cccagtagtt acgcggcgag
     5701 agggtgatgc gtttgccttg ctccaggtag ccgctgcgca gggtttgggt gtagaacccc
     5761 tgaatgttga atttatgctg gctgtctggc tggaactggt agcccaggct cgccagcttg
     5821 cgacgacccc agaagcggtc atacgggcgg gtggattgcc agcgatcggc gtcgtaatcc
     5881 gcgcgagaca ggccaccggg catgtcggct tcaccgtcgt aatattgcag caggctgttg
     5941 aaggtgtgca cctcatccgg cgcatatttg cttttcagca tcaggtcgtc gatgcgggtg
     6001 gcgctgtgct cgcgccagtc actgccgcgc gtgccggagt agagcagcgc ggtgccaaaa
     6061 ccgttgtccg ctgtgccgcc caccatcagg ttgtgcgtct ctttcgggtt gttttgtgaa
     6121 gaggttgggc tgagctgacc ttccacgccc gcctcgatac caaagtcctg cggaatggca
     6181 cgggtaacaa agttcaccac gccgcccacg ctctgcggtc cgtaacgcac cgcaccacca
     6241 ccgcgtacca cgtcaatggc atccatgttg ccgagcgaaa cgggagccag tgaaagctgc
     6301 ggctgaccgt aaggggcgaa ggggacgggg atgccgtcca tcaggacggt cgagcggctg
     6361 gtgaggcgcg ggttcaggcc ccggatgcca aagttcatcg ccaggtcgtg gctgccggtg
     6421 ccgttgtttt ccggcgcgct gacgccaggg atgcggttaa gtacctcacg catggtggtt
     6481 gcgccggttt tggcgaaatc ctcacggcgg atcacgtcac gcgcgccagc atgttcaaat
     6541 acgtcgtttt cacgcgcatc acccagccag tcgccgacca cggtcagggc atcttctttt
     6601 ggtgcgggcg cgggctccag cgtccagcta ttatttccca gcggttttac ctgcagtccg
     6661 ctgccgtcca gcagttgttg caggccgctc tcgacgtcgt aatcgccgtg caggccgttg
     6721 ctctgcttgc cgcgcgtcag gctggcgtca accgagaggg taaatccgct gtgtgcggca
     6781 tactgattga gcgctttatc gagcgatccc ggtgcgatat taacctgtgc agcaaaagcg
     6841 gaaaacgaga gaccggccag cggcagcagg ctcaggcgaa tggcgttaac caaaggtgtt
     6901 gttttacgaa aaacgcgtaa cggcgtcata ccttccccat catcattttt gttgtgttca
     6961 gctatgagtc gaacgagaag ggtaaaaagg acaatcgaaa taagaattat tttccttaca
     7021 gtggtgaaat gtttatccag taccgcgtaa tagactgaat tttaacggga agcgtttgcg
     7081 cgataacgtt caggatcgca tcggtatttt tcagcgggaa cgtcccgctc aggcgcagcc
     7141 cggcaacggc gggatcgcag cgcagcacgc cgttgcggta acgggttagc gtggctatca
     7201 cctcacccag tggtttatcg ctgaagctca ggatgtcctt cgtccagctt gtactctcgt
     7261 catccagcgg tttcactgcg ccaaactcag aggcgctgaa ctgcaggctt tcaccagcgt
     7321 tcacgatgcg tttttgcgcg ggggcactgg cgagaagcac ttccacagcg tgctgctgaa
     7381 cgtcaagctg cgtgaaatta tcctgctggc ggacggtaaa ttctgtccct aaagcagtga
     7441 gctggccctg acgggtcagg acacggaagg ggcgttgcag ggcatctttc gcggtagtaa
     7501 tggcgatttc accgtaccag agccggacgg tgcgctgatg cgcatcaaaa cgcacatccg
     7561 ccgcgctttg ggtattcagc gtgagcaggg agccatcttc cagttgctga cggctgactg
     7621 tgcctttggc ggtgcggtaa tctgcccgca gaccttcgcc ggtttccgac tgccagagct
     7681 gccagcctcc gccagcgccg agcaacagca gtaatccttt catcacgtga cggcgggtga
     7741 ggcgggtatc gtgcaacgcc cggctggcaa cgtcgccagg cacaccgcca agctggttgc
     7801 gcaggttttc aacctgctgc caggcccact ggttatcctg atcctgttca taccactgtt
     7861 gccagcgcgc ttcctgttgt gggctgacgc gctcgccgct tagcacggca taccagtggg
     7921 aagctgaacg cagcgcctga cggcgggaat cggttaacaa aggattcata acccatactc
     7981 cagacggaac agcaggcagt gctcgacggc tttcgccacg tattttttca cggagctgat
     8041 ggaaacaccg agtttgtgcg caatctcgct gtatgtcaga ccatccagtt gcgaaagcag
     8101 aaacgcttca cgtgttttgc cgtttagccc gtccagcatg ctgtcgagga gttgtagggt
     8161 ctcgagttgg ctttcgcgtt cctcaggtga aggcgctccc ccctccggca taagcgccag
     8221 catctccaga tacgcttttt ccagcgcgtt tcggcgaaac aggtccacca tcacgcgttt
     8281 ggcgatagtg cagaggaagg agcgaggatc gcggatcgtc gagagcgttt cgctgaccat
     8341 tacccgcaaa aaagtgtcct gggcaatgtc atctgcatca aaagcagact ggagtttgcg
     8401 cgtcagccag cttttcaacc agccgtgatg tgtgccataa agcgactcga acgttaagga
     8461 agctgtggta gtggcgcggt cagacatgcg gagtgcatca aaagttaatt atcacgtagt
     8521 catattaata tgagaatggt tatcattaca attggaaata aaattgtttc caatagacat
     8581 ttttaacatg ttgtttttct aagtgttata aggtaggtat aaaatgggat ggagcctctg
     8641 cttctggcat gtgtcggtca gaatgactca tgatgtggtc tgctattatt gacatcctca
     8701 ctgccctaaa ggatggggat ttcggtaatg ctgccaactt actgatttag tgtatgatgg
     8761 tgattttaag gtgcttgcgt ggcttccatt tccatcagat gtccttcctg ctccgctact
     8821 gaaggcgtgg tgcgtaacgg caaaagcact gccggacatc agcgctatct ctgctctcat
     8881 tgccgtaaaa catggcaact acagttcact tacaccgcct ctcagcccgg tacgcaccag
     8941 aaaatcattg atatggccat gaatggcgtc ggatgtcgcg ccagtgcacg cattatgggc
     9001 gttggcctca acacggtttt acgtcactta aaaaactcag gccgtagtcg gtaacctcgc
     9061 gcatacaacc gggcagtgat gtgattgtct gcgctgaaat ggacgaacag tggggctacg
     9121 tcggtgctaa atcacgtcag cgctggctgt tttacgcgta tgacaggata cggaggacgg
     9181 ttgtggcgca cgtcttcggt gaacgcactc tggccacact ggagcgtctt ctgagcctgc
     9241 tgtcggcctt tgaggtcgtg gtatagatga cggatggctg gccgctgtat gaatcacgcc
     9301 tgaagggaaa gctgcacgtt atcagcaagc gttacactca gcgcattgag cgacataatc
     9361 tgaatctgag acaacatctg gcaaggctgg gacggaagtt actgtcgttc tcaaaatcgg
     9421 tggagttgca tgacaaggtg aaccgccccg ggaatcctgg agactaaact tcctgagaaa
     9481 gaggtaaaca ggatgactaa aaatactcgt ttttc
//
