LOCUS       NZ_CP069906            27963 bp    DNA     linear   CON 05-JAN-2024
DEFINITION  Klebsiella pneumoniae strain FDAARGOS_1313 plasmid unnamed6.
ACCESSION   NZ_CP069906
VERSION     NZ_CP069906.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN16357455
            Assembly: GCF_016903395.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 27963)
  AUTHORS   Sokurenko,E., Tallon,L., Sadzewicz,L., Zhao,X., Boylan,J., Ott,S.,
            Bowen,H., Vavikolanu,K., Mehta,A., Aluvathingal,J., Nadendla,S.,
            Yan,Y. and Sichtig,H.
  TITLE     FDA dAtabase for Regulatory Grade micrObial Sequences (FDA-ARGOS):
            Supporting development and validation of Infectious Disease Dx tests
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 27963)
  AUTHORS   Sokurenko,E., Tallon,L., Sadzewicz,L., Zhao,X., Boylan,J., Ott,S.,
            Bowen,H., Vavikolanu,K., Mehta,A., Aluvathingal,J., Nadendla,S.,
            Yan,Y. and Sichtig,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-FEB-2021) Institute for Genome Sciences, University of
            Maryland School of Medicine, BioPark II, 801 W. Baltimore St., Suite
            619, Baltimore, MD 21201, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT v. 8.0.0, HGAP v. 4
            Genome Coverage                   :: 1345.58x
            Sequencing Technology             :: Pacbio; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/05/2024 08:17:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,757
            CDSs (total)                      :: 5,632
            Genes (coding)                    :: 5,468
            CDSs (with protein)               :: 5,468
            Genes (RNA)                       :: 125
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 88
            ncRNAs                            :: 12
            Pseudo Genes (total)              :: 165
            CDSs (without protein)            :: 164
            Pseudo Genes (ambiguous residues) :: 0 of 165
            Pseudo Genes (frameshifted)       :: 77 of 165
            Pseudo Genes (incomplete)         :: 94 of 165
            Pseudo Genes (internal stop)      :: 28 of 165
            Pseudo Genes (multiple problems)  :: 29 of 165
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP069906.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..27963
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="FDAARGOS_1313"
                     /host="Homo sapiens"
                     /culture_collection="FDA:FDAARGOS_1313"
                     /db_xref="taxon:573"
                     /plasmid="unnamed6"
                     /geo_loc_name="USA: WA"
                     /collected_by="ARMADA"
     gene            complement(<1..445)
                     /locus_tag="I6K43_RS02730"
                     /old_locus_tag="I6K43_02730"
                     /pseudo=""
     CDS             complement(<1..445)
                     /locus_tag="I6K43_RS02730"
                     /old_locus_tag="I6K43_02730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008109360.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="reverse transcriptase domain-containing protein"
                     /name="reverse transcriptase domain-containing protein"
     gene            complement(1480..1785)
                     /locus_tag="I6K43_RS02735"
                     /old_locus_tag="I6K43_02735"
     CDS             complement(1480..1785)
                     /locus_tag="I6K43_RS02735"
                     /old_locus_tag="I6K43_02735"
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="WP_004181854.1"
                     /translation="MTRKLSTEFKREFADLVIVHGYKHKDAADAMGVGLSSIQRWVSQF
                     KKEQQGITPKATALTPEQLRIQQLEKQVKQLESDNALLKKASPFFAMEMNNGSKSR"
                     /name="IS3 family transposase"
     gene            2067..3035
                     /locus_tag="I6K43_RS02740"
                     /old_locus_tag="I6K43_02740"
     CDS             2067..3035
                     /locus_tag="I6K43_RS02740"
                     /old_locus_tag="I6K43_02740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611102.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS903B family transposase"
                     /protein_id="WP_077265954.1"
                     /translation="MKDQITHLPDNADRSVAKQKLKITNWPTYNKALINRGSITFWLDD
                     EAIQAWYESATPSSRGRPQRYSDLAITTVLVIKRVFRLTLRAAQGFIDSIFSLMNVPLR
                     CPDYSCVSRRAKSVNVSFKTSTRGEIAHLVIDSTGLKVFGEGEWKVKKHGQERRRIWRK
                     LHLAVDSNTHEIICADLSLNNVTDSEAFPGLIRQTHRKIRAASADGAYDTRLCHDELRR
                     KKISALIPPRKGAGYWPGEYADRNRAVANQRLTGSNARWKWTTDYNRRSIAETAMYRVK
                     QLFGGSLTLRDYDGQVAEAMALVRALNKMTKAGMPESVRIA"
                     /name="IS5-like element IS903B family transposase"
     gene            3101..3889
                     /locus_tag="I6K43_RS02745"
                     /old_locus_tag="I6K43_02745"
     CDS             3101..3889
                     /locus_tag="I6K43_RS02745"
                     /old_locus_tag="I6K43_02745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014611871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heteromeric transposase endonuclease subunit
                     TnsA"
                     /protein_id="WP_048268744.1"
                     /translation="MNWVKQGRGKGSGKDYQPWLTVRDLPSAGRSHRIWGFQTQRTHHL
                     LSDLELAAFFLFDWNPSVTDIREQYPLRLEDTIELAAQARIRHPEVRGQIQVMSTDFLV
                     DTNKPELPRMAIQVKTSSDLSNPRTIEKLELERRYWALKEVPWYLLTEKQIPKTVTKNI
                     AWLYPAQLVLDGIEDTLHMASLYLSFFINHPTLLISQVAMMLDQAYSLSPGESLQKIRS
                     LLALRVFLFDIRRPWSTLTVGELQASSDIDSLRNYYVANQ"
                     /name="heteromeric transposase endonuclease subunit TnsA"
     gene            3873..5947
                     /locus_tag="I6K43_RS02750"
                     /old_locus_tag="I6K43_02750"
                     /pseudo=""
     CDS             3873..5947
                     /locus_tag="I6K43_RS02750"
                     /old_locus_tag="I6K43_02750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000944484.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /name="transposase"
     gene            5944..6366
                     /locus_tag="I6K43_RS02755"
                     /old_locus_tag="I6K43_02755"
     CDS             5944..6366
                     /locus_tag="I6K43_RS02755"
                     /old_locus_tag="I6K43_02755"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_048268742.1"
                     /translation="MTLPKGMVQAIYNDTGISQYQGNPLIEALPPILDRRQLKDGLSGQ
                     IMFRPTDVYLDGQTRVHVISQLLDNFFQPLSRHIELESKLSVMLRQGYVGRNLATGELN
                     AHIQNGYERVMQGGLAVFRFEHVESTAKEGANKFLI"
                     /name="hypothetical protein"
     gene            6407..7387
                     /locus_tag="I6K43_RS02760"
                     /old_locus_tag="I6K43_02760"
     CDS             6407..7387
                     /locus_tag="I6K43_RS02760"
                     /old_locus_tag="I6K43_02760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000019445.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element ISKpn26 family transposase"
                     /protein_id="WP_004179076.1"
                     /translation="MSHQLTFADSEFSTKRRQTRKEIFLSRMEHILPWQNMTAVIEPFY
                     PKAGNGRRPYPLETMLRIHCMQHWYNLSDGAMEDALYEISSMRLFARLSLDSALPDRTT
                     IMNFRHLLEQHQLARQLFKTINRWLAEAGVMMTQGTLVDATIIEAPSSTKNKEQQRDPE
                     MHQTKKGNQWHFGMKAHIGVDAKSGLTHSLVTTAANEHDLNQLGNLLHGEEQFVSADAG
                     YQGAPQREELAEVDVDWLIAERPGKVKTLKQHPRKNKTAINIEYMKASIRARVEHPFRI
                     IKRQFGFVKARYRGLLKNDNQLAMLFTLANLFRVDQMIRQWERSQ"
                     /name="IS5-like element ISKpn26 family transposase"
     gene            7369..7566
                     /locus_tag="I6K43_RS28935"
     CDS             7369..7566
                     /locus_tag="I6K43_RS28935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001340235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_323128110.1"
                     /translation="MGEISVKTGNNARNGGKNSLNRLIRCVCGKKIGPDPRNFNQRVSL
                     GRNDLLIRTFLSGKCKTRHR"
                     /name="hypothetical protein"
     gene            7511..7858
                     /locus_tag="I6K43_RS02765"
                     /old_locus_tag="I6K43_02765"
     CDS             7511..7858
                     /locus_tag="I6K43_RS02765"
                     /old_locus_tag="I6K43_02765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_227651184.1"
                     /translation="MTCLFAPSLAENAKHGTANADEPVSVLDNDCQTTSGIDDQGNSID
                     GGKALQIADHERKLVAVTHGQVITEALNATSDFLDTDCVMDRLGISYEEAELRSSGAME
                     LHNALIEWSKD"
                     /name="hypothetical protein"
     gene            7919..8083
                     /locus_tag="I6K43_RS02770"
                     /old_locus_tag="I6K43_02770"
     CDS             7919..8083
                     /locus_tag="I6K43_RS02770"
                     /old_locus_tag="I6K43_02770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004026392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004026392.1"
                     /translation="MKINEQLLSALLAALEWIDAVPSDTVLPAMPGFDRDEVNELIANA
                     RKELQTETN"
                     /name="hypothetical protein"
     gene            8739..9074
                     /locus_tag="I6K43_RS28635"
     CDS             8739..9074
                     /locus_tag="I6K43_RS28635"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_228293761.1"
                     /translation="MTTATMATPAKAKNENVSLRTFLEKNGIGGRLGNGLVMDPTHLNI
                     ILALTHVPLAWVRLTGNSRKLRTTWRVWLSNMPIALWKWPLWLSRFVMVRLSFVRDTAV
                     TVQFPGK"
                     /name="hypothetical protein"
     gene            9246..9983
                     /locus_tag="I6K43_RS28640"
     CDS             9246..9983
                     /locus_tag="I6K43_RS28640"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_228293762.1"
                     /translation="MSIEELAADRKVSVTHVRKLLKVHTAPEALKGLIVKGVVAYYAAL
                     DVMEKYPDNCVAIIQEAFDKFGKATDKTIGQVLLAKRTGENDTNGESDGNVTTITTTDA
                     GNGSNSASDAAAGVIESSAGNDAGVAGGGSEEGEGGEKSEPKRTPAAKREPKQNIKSQP
                     SVFDVLPKKISKEIVDNSLDVINRIVTEAKEIPFMEDGAEVLAKAQYQLTLTYEEFLQL
                     TAAKDSYDKHLEKIQKKTQSNNI"
                     /name="hypothetical protein"
     gene            10823..11062
                     /locus_tag="I6K43_RS28645"
     CDS             10823..11062
                     /locus_tag="I6K43_RS28645"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_228293763.1"
                     /translation="MKGINQSNGNHLKFLYGVTSTDRLIQHEHADKFIDSCIKNIGSIH
                     KMSLACYRAGGPLTELVLFTVRTKHSQSPLALAM"
                     /name="hypothetical protein"
     gene            12020..13016
                     /locus_tag="I6K43_RS02785"
                     /old_locus_tag="I6K43_02785"
                     /pseudo=""
     CDS             12020..13016
                     /locus_tag="I6K43_RS02785"
                     /old_locus_tag="I6K43_02785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229637.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /name="IS110 family transposase"
     gene            complement(13198..13401)
                     /locus_tag="I6K43_RS02790"
                     /old_locus_tag="I6K43_02790"
     CDS             complement(13198..13401)
                     /locus_tag="I6K43_RS02790"
                     /old_locus_tag="I6K43_02790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004197809.1"
                     /translation="MSYGWLFESPDDDISGDNHINLEHLPPELKQVAIQIGVASENGIY
                     GHSRFCNTDFDDKLACLNLSGV"
                     /name="hypothetical protein"
     gene            complement(13415..13618)
                     /locus_tag="I6K43_RS02795"
                     /old_locus_tag="I6K43_02795"
     CDS             complement(13415..13618)
                     /locus_tag="I6K43_RS02795"
                     /old_locus_tag="I6K43_02795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HHA domain-containing protein"
                     /protein_id="WP_004197808.1"
                     /translation="MTKQEWILRLRRCTSKETLERIIEKNKYSLSDDELEHFNAAVDHR
                     LAEMTMGKLYDRVPSGVWKFVK"
                     /name="HHA domain-containing protein"
     gene            complement(13652..14020)
                     /locus_tag="I6K43_RS02800"
                     /old_locus_tag="I6K43_02800"
     CDS             complement(13652..14020)
                     /locus_tag="I6K43_RS02800"
                     /old_locus_tag="I6K43_02800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004197807.1"
                     /translation="MKTAIWVVVYLTMCFLLFTGWMFAFAQYAPYNGQEHAFSLTYLLN
                     LFFLHVVMVPYYEFFQTETYSNVLMSLADESGQMIRFHHVVPVLRIYSLSALLTFVGYI
                     IYAKWFTHNWLKGKLLPK"
                     /name="hypothetical protein"
     gene            complement(14064..14558)
                     /locus_tag="I6K43_RS02805"
                     /old_locus_tag="I6K43_02805"
     CDS             complement(14064..14558)
                     /locus_tag="I6K43_RS02805"
                     /old_locus_tag="I6K43_02805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020805591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_020802777.1"
                     /translation="MKVTEPGLNTLIDNLNTLICEDSLLTRQERETLVLAVAAIGAMKA
                     RVGLKKGEAPAVARREKREKKDRQPDPRFPRAGHPWQEDEKTLLSDALDSVPDEEIGRH
                     LFWLSEKLGRTPFSVAFQIAAIRELQDGWEEQFREISDIIRLSGLSISDYLKQNGTGHN
                     A"
                     /name="hypothetical protein"
     gene            complement(14589..15164)
                     /locus_tag="I6K43_RS02810"
                     /old_locus_tag="I6K43_02810"
     CDS             complement(14589..15164)
                     /locus_tag="I6K43_RS02810"
                     /old_locus_tag="I6K43_02810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_020317495.1"
                     /translation="MAAVTTSRRPSPLQRRVLIVLAALDAKRPGPVATRDIERVLEQGG
                     DAPVYGPNLRASCRRMEAAGWLRTLRAPNLQLAVELTEAGRGIAEPLFQAEREAETARQ
                     RLTDVRRLPLRQTAAGDAVELQLDDGHYTIREAAYVIRLDGTTCLQLTDAGGIRRIKEG
                     DPLQVASWYQACFDAGLPVIVQVNESRD"
                     /name="hypothetical protein"
     gene            complement(15152..15421)
                     /locus_tag="I6K43_RS02815"
                     /old_locus_tag="I6K43_02815"
     CDS             complement(15152..15421)
                     /locus_tag="I6K43_RS02815"
                     /old_locus_tag="I6K43_02815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019706036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_020804424.1"
                     /translation="MDEKVYFRLSYETMTADTEDFINGCLERAGRADCNDPDAEIAWAR
                     SAIELWYHLAMAGRAPEDVADRDHLRLTGMLLRAPTAEQRSWQQ"
                     /name="hypothetical protein"
     gene            15858..16547
                     /locus_tag="I6K43_RS02820"
                     /old_locus_tag="I6K43_02820"
     CDS             15858..16547
                     /locus_tag="I6K43_RS02820"
                     /old_locus_tag="I6K43_02820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020315560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RES family NAD+ phosphorylase"
                     /protein_id="WP_020315560.1"
                     /translation="MSSKSGVNPNDEVNQTVETSLNAGMNEQDVASLDKIGKLQDEQLQ
                     RCGMTVPSGTEVFRLQLGSHGGSSVFFNRNGEDCRYSLNDGENGSMYVAKTPDTAMKEV
                     FQHKTGLRESDLDNYIMGTVVIEKDIRVLQVSKLIKCSDLRLNDVTTSTRAVTHQLAEK
                     VHSAGFDGMEFPSNVTSDPCLVLWHDDPAGTGMAITRSQTSLSQFEYQGKEAADILVYD
                     LGIPVEE"
                     /name="RES family NAD+ phosphorylase"
     gene            complement(16579..17268)
                     /locus_tag="I6K43_RS02825"
                     /old_locus_tag="I6K43_02825"
     CDS             complement(16579..17268)
                     /locus_tag="I6K43_RS02825"
                     /old_locus_tag="I6K43_02825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004193995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004193995.1"
                     /translation="MNTSTQKRNGNDRSSTMHNFLDNSIAAERLENFFQDLVEEVRSGK
                     TPIAPESMGNTDAVFTMDVILKLLENRAVNSLTPEKKRQQRRLHSKALFLQRLENDGGV
                     YTSAKAAEMVGKSKPTVKTWKDTDQLLALDIDGEFYYPVFQFTDEEGISDKGVLRGVAE
                     LLTMLSSFSDRMKYSFFMEQRNTVLDGLNPAGRSFTVAEVLKGNPDEKVMNELRRLARN
                     YGTQNAV"
                     /name="hypothetical protein"
     gene            <17408..17652
                     /locus_tag="I6K43_RS28940"
                     /pseudo=""
     CDS             <17408..17652
                     /locus_tag="I6K43_RS28940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234208.1"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            17822..18040
                     /gene="ccdA"
                     /locus_tag="I6K43_RS02830"
                     /old_locus_tag="I6K43_02830"
     CDS             17822..18040
                     /gene="ccdA"
                     /locus_tag="I6K43_RS02830"
                     /old_locus_tag="I6K43_02830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin CcdA"
                     /protein_id="WP_004197642.1"
                     /translation="MKQRITVTIDSDSYQLLKSADVNISALVNRAMQNEARRLRAERWQ
                     AENQEGMAEVARFIEMNGSFADENRDW"
                     /name="ccdA"
     gene            18042..18347
                     /gene="ccdB"
                     /locus_tag="I6K43_RS02835"
                     /old_locus_tag="I6K43_02835"
     CDS             18042..18347
                     /gene="ccdB"
                     /locus_tag="I6K43_RS02835"
                     /old_locus_tag="I6K43_02835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin CcdB"
                     /protein_id="WP_016946795.1"
                     /translation="MQFKVYAYKRESRYRLFVDVQSDIIDTPGRRMVIPLASARLLSDK
                     VSCELYPVVHIGDDSYRLMTTDMASVTSSVTGEEVADLSHRENDIKNAINLMFWGI"
                     /name="ccdB"
     gene            18505..19188
                     /locus_tag="I6K43_RS02840"
                     /old_locus_tag="I6K43_02840"
     CDS             18505..19188
                     /locus_tag="I6K43_RS02840"
                     /old_locus_tag="I6K43_02840"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_023280892.1"
                     /translation="MADGISVWVPVISTLSGGILTGSIALLVSRLNHRYAGEREALAAA
                     ERHRHELKIAQELLDKERLFIATELIFLLEQFAEGCARMATDCGEPDPQGVYTPTENLP
                     ELIIKNISGDWRALPPPIMYRIHELPVLQNEVRRHLAAYYEQYWEPPYLSPYYRERQFH
                     YARLGIKAVILAQRLRKLVGLPGTRLDATEWSAQLVLSRVWRKKRKERTEAKIRRLRKK
                     TGENS"
                     /name="hypothetical protein"
     gene            19191..19967
                     /locus_tag="I6K43_RS02845"
                     /old_locus_tag="I6K43_02845"
     CDS             19191..19967
                     /locus_tag="I6K43_RS02845"
                     /old_locus_tag="I6K43_02845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016528858.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA];
                     GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="WP_049245386.1"
                     /translation="MPTIQGQRVTHTSAQLPVAIDYPAALALRQMALVQDELPKYLLAP
                     EVSALLHYVPDLHRKMLLATLWNTGARINEALALTRGDFSLAPPYPFVQLATLKQRTEK
                     ATRTAGRSPAGSQAHRLVPLSDHHYVSQLQMMVATLKIPLERRNKRTGRTEKARIWDIT
                     DRTVRTWIGEAVEAAAVDGVTFSVPVTPHTFRHSYAMHMLYAGIPLKVLQSLMGHKSIS
                     STEVYTKVFALDVAARHRVQFQMPEADAVAMLKGNI"
                     /name="site-specific integrase"
     gene            complement(20025..20282)
                     /locus_tag="I6K43_RS02850"
                     /old_locus_tag="I6K43_02850"
     CDS             complement(20025..20282)
                     /locus_tag="I6K43_RS02850"
                     /old_locus_tag="I6K43_02850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000764642.1"
                     /translation="MKLETIQIDNTVRSGLNSFTDGVIIRDTKVLITLNLPDGQKTTIE
                     GEWRHMSDANRLSERITMLQHAIYEQYEEYRADIPVSWSR"
                     /name="hypothetical protein"
     gene            complement(20411..20515)
                     /locus_tag="I6K43_RS02855"
                     /old_locus_tag="I6K43_02855"
     CDS             complement(20411..20515)
                     /locus_tag="I6K43_RS02855"
                     /old_locus_tag="I6K43_02855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032409716.1"
                     /translation="MRSFTIMSLLETFLTASQGATILFLAMLIYWQKR"
                     /name="hypothetical protein"
     gene            21050..21916
                     /locus_tag="I6K43_RS02860"
                     /old_locus_tag="I6K43_02860"
     CDS             21050..21916
                     /locus_tag="I6K43_RS02860"
                     /old_locus_tag="I6K43_02860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004118283.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_004118283.1"
                     /translation="MGKRSSSVLNYPLVDKVQIFPVDKYRDSLQFLFSLSLWVGKNLPI
                     GIEMDTQALLPATKTFKKRASIKQSNELTEAAYYLPLQAKRVLWLCLMQAYFNDSQEDD
                     SDVLPLFKISVSDYVKYFNVATSVASRDVKAGVNALGESTVTFYPKEGEFEEVKRPWLA
                     EAGMKRGRGSWQIEFNYKVMPFLVGLTSQFTTYSLYDCGQLNSVRVIRLYESLCQFRST
                     GVWITTHDWLCERFMLPASQKNNIAEMKRTFLEPALKKINEKTPLKVTYTTEEDGRLLF
                     NFLDKKQ"
                     /name="replication initiation protein"
     gene            complement(22273..22542)
                     /locus_tag="I6K43_RS02865"
                     /old_locus_tag="I6K43_02865"
     CDS             complement(22273..22542)
                     /locus_tag="I6K43_RS02865"
                     /old_locus_tag="I6K43_02865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000339857.1"
                     /translation="MDAPDYGKQVNFADGPDYGKQVNFTGGRECGEQVNFADGPDYGKQ
                     VNFAGGRDCGKQVNFADGPDCGKQVNFAGGRECGEQVNFADGPD"
                     /name="hypothetical protein"
     gene            22957..24162
                     /locus_tag="I6K43_RS02870"
                     /old_locus_tag="I6K43_02870"
     CDS             22957..24162
                     /locus_tag="I6K43_RS02870"
                     /old_locus_tag="I6K43_02870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000368714.1"
                     /translation="MDNIEQLRKVATRAGKLLTSLSESIRQQKEELKLTEFYQEYSKAA
                     LYKLPKLSKGSVEYAVSEMEAGGYIFKKKPSGNTMKYAMTIQNVIDLYNHRKVPKYRDR
                     FDKAFTIFVCNLKGGGSKTVSTASLSHAFRAHPQLLFEDLRILAIDFDPQASLTMFLSH
                     ENSVGLVENTAAQAMLQNVSREELLSDFIVPSIIPGVDVIPASIDDAFLAEGWKGLCEE
                     HLPGKNIHAVLKENIIDKLQHDYDFIFLDSGPHLDAFLKNCIGAADLMLTPLPPATVDF
                     HSSLKFVASLPALIDSIEMDGHTCNLIGNVGFMSKILNKSDHKICHSQAKEVFGADMLD
                     MVLPRLDGFERCGETFDTVISANPATYDGSTEALKSAKSAAEDFAKAVFDRIEFIRTNG
                     GM"
                     /name="AAA family ATPase"
     gene            24162..25136
                     /locus_tag="I6K43_RS02875"
                     /old_locus_tag="I6K43_02875"
     CDS             24162..25136
                     /locus_tag="I6K43_RS02875"
                     /old_locus_tag="I6K43_02875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB family protein"
                     /protein_id="WP_000064120.1"
                     /translation="MSNEKRKTIGRQLNTQASMLEMADTGRSQVFTLKTGRKVTFRFVR
                     VPASEVESKTFVNQENNGRDQLALTRESLKSIIQTIKFQQFFPCIGIKQSERIEILDGS
                     RRRASAIFVRTGLDVMVTEEHLSADEARQLAKDIQTAKEHNLREIGLRLIALKESGFNQ
                     KEIAELEGLSQAKVTRALQAAAVPQDLISLFPVQSELSFSDYKLLLEVNEKLGEKGLTP
                     EELIQSVSAQLDAILSDGERPEDEQKASILKLISQASQALIDPSPKEKSVVSPLWSFEE
                     KDKFARKRVKGRTLTYEFSRMSKVIQDELDKAINEVLDRNLSQ"
                     /name="ParB family protein"
     gene            complement(25218..26487)
                     /locus_tag="I6K43_RS02880"
                     /old_locus_tag="I6K43_02880"
                     /pseudo=""
     CDS             complement(25218..26487)
                     /locus_tag="I6K43_RS02880"
                     /old_locus_tag="I6K43_02880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229773.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /name="Y-family DNA polymerase"
     gene            complement(26487..26918)
                     /gene="umuD"
                     /locus_tag="I6K43_RS02885"
                     /old_locus_tag="I6K43_02885"
     CDS             complement(26487..26918)
                     /gene="umuD"
                     /locus_tag="I6K43_RS02885"
                     /old_locus_tag="I6K43_02885"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229772.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translesion error-prone DNA polymerase V
                     autoproteolytic subunit"
                     /protein_id="WP_000776034.1"
                     /translation="MKLQLFSTGKELPPQAHPLFADLASCGFPSPAADYVESDLDLHDY
                     CIRHPSATYYLRASGDSMADGSLYNGDLLVVDSAEKPRHGDIVVASMQGEFTVKRLLLT
                     PRLTLQPMNASWSPIYPDPDELDIFGVVTHIIHRPREMY"
                     /name="umuD"
     gene            27323..>27958
                     /locus_tag="I6K43_RS02890"
                     /old_locus_tag="I6K43_02890"
                     /pseudo=""
     CDS             27323..>27958
                     /locus_tag="I6K43_RS02890"
                     /old_locus_tag="I6K43_02890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226014.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="reverse transcriptase domain-containing protein"
                     /name="reverse transcriptase domain-containing protein"
     Typing          21051..21945
                     /name="IncR"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.33"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gtaattgcac cgttcgaata gcgtgatgtc actgcgctct ggtctgaagc cgtaggacaa
       61 cgagtggaaa tcgtttccca tataggctcc attgccatca acatggcacg ttgtactatt
      121 ctgtctttca aggttggaat acctagtggc cgttgtttac catttgcttt gggaatatat
      181 actcgccttg ccggcatagg ttgatagtca cctgacaata aagtttgtct aatatcatca
      241 aggtaactat ctaaattgtc ctgcaagtgc gactttgtta ttccatcaca ccggccgttt
      301 tagcgccggc tgatgaaagc gtgatattag cagcatgcca cagccattca gggtgactga
      361 taagccttaa tagtcgatta actcgacgtc ctttatcagt caatgtccat gttgctaatt
      421 tgcgttgcat ttcactgatt atcaaaggtc ttcacctcat taaaggtcag gtagttcgct
      481 tcgcaaatca tataactgca ccccttcgcc atgtagtggg ctttccccac ctcagactac
      541 tacgggcgct ccgccaactt gcataacatc ggggtctgct ccctaacatt caatacaagt
      601 cttcctcggt tcatctattt gaactaaaac atagtgggtg gatgccgatc gcagtcttta
      661 accttatcgt actgtaagat ggcgatacca aaacgaagaa ttgtgtataa cgtttatcca
      721 gtgacaaatc catacgtgtt atttatcaaa tcggtgatgt tccccataca tgtagtcaca
      781 tcacggtatc cgcacagcct attaattcgt gtaggctggg cgacgtttca gcccatagat
      841 gcgggttaat cggttcatgt tcttcatccg tccactactc agtctagaaa agcatattgg
      901 cttaacgaat tcgcctcact tcccgttgtc agtgggttac atcacctcat tagcatacaa
      961 tgagtcactg ccactcagac tctgtcacct gcacaaccag ataacggcaa taaacattta
     1021 actcctgtta tttgttcatg aatttcaata gactcgtggt ttattaccaa cccccatatt
     1081 gacgttaaac tccgagcaca catacgtaat atcacccgac caatgtgtat ttaacaactc
     1141 aggattaaaa ctgtctattc agtgtattag gtgcaatcac agacgctttg ccaccaactg
     1201 ggatacttgt gttgtttagg ccgcttggca atgagcttga gtcgtttcaa aaacgacgaa
     1261 ccttatcaat ccccaattta aagcccatat ccaacagctc agataacatc ctgcgtttgc
     1321 cgtacgttgc atccatatca ttgtgaatat gcttcatagc ggctctagcg aactttctca
     1381 gcattaatcg atttaggctt aaccgataat aaatgaacta gcagctaact ttaaaacaac
     1441 gacatatttg ctgaacttga tgacccgcct tcttcagctt taccgcgact tgctgccgtt
     1501 gttcatttcc atagcgaaga agggtgacgc tttttttaat aaggcattgt cactttctaa
     1561 ctgtttaact tgtttttcta actgctgaat acgtaattgc tctggtgtta atgctgtagc
     1621 tttaggggtt ataccttgtt gttctttttt aaactggcta acccaacgct gaatcgacga
     1681 taaaccaacg cccatcgcat ccgccgcatc tttatgttta tatccatgaa cgataactaa
     1741 gtctgcaaat tctcgcttaa actcagttga taattttctt gtcatttaaa acctctttag
     1801 ttgtattaat aatacctcta actaggtctc caagataagt ctaccgttac agtaatccca
     1861 attgctctag actggagaac cgtcctcaaa catgaggacg gtaatgtttc ggacagtttg
     1921 gcaatgttta ctttacgcca aatgttttat tgaacatctc agcgatatga ccgcctactg
     1981 tgataggttc ggggtactct tcgtcgggct tgcgcaaagt tggaaccact gaagggcttt
     2041 gttgaataaa tcgaactttt gctgagttga aggatcagat cacgcatctt cccgacaacg
     2101 cagaccgttc cgtggcaaag caaaagttaa aaatcaccaa ctggcccacc tacaataaag
     2161 ccctcatcaa ccgtggctcc ataactttct ggctggatga tgaagctatt caggcctggt
     2221 atgagtcggc aacgccttca tcacggggaa gacctcagcg ctattctgac cttgccatca
     2281 cgactgtgct ggtcattaaa cgcgtattca ggctgaccct gcgcgctgca cagggtttta
     2341 ttgattccat tttttctctg atgaacgttc cgctacgctg cccggattac agctgtgtca
     2401 gcaggcgggc aaagtcggtt aatgtcagtt tcaaaacgtc cacccggggt gaaatcgcgc
     2461 atctggtgat tgattccacc gggctgaagg tctttggtga aggcgaatgg aaagtcaaaa
     2521 aacacggcca ggaacgccgt cgtatatggc gaaagttgca tctggcagtt gacagcaaca
     2581 cacatgaaat catctgtgca gacctgtcgc tgaacaatgt gacggactca gaagccttcc
     2641 cgggtcttat ccggcagact cacagaaaaa tcagggcagc atcggcagac ggcgcttacg
     2701 acacccggct ctgtcacgat gaactgcggc gtaagaaaat cagcgcgctt atcccgcccc
     2761 gaaaaggcgc gggttactgg cccggtgaat atgcagaccg taaccgtgct gttgcgaatc
     2821 agcggctgac cgggagtaat gcgcggtgga aatggacaac agattataac cgtcgctcga
     2881 tagcggaaac ggcgatgtac cgggtaaaac agctgttcgg gggttcactg acactgcgtg
     2941 actacgatgg tcaggttgca gaggctatgg ccctggtacg agcgctgaac aaaatgacga
     3001 aagcaggtat gcctgaaagc gtgcgtattg cctgaaaaca caacccgcta cgggggagac
     3061 ttacccgaaa tctgatttat tcaacaaagc ctctcgttca ctgaattggg ttaaacaagg
     3121 tcgtggaaag gggtcaggaa aagattacca accctggttg accgtcagag acctgccttc
     3181 tgctggacga tctcaccgta tctggggatt ccagactcaa cgaacccacc atctgttgtc
     3241 agacctagag ctggcggcgt tttttctgtt tgattggaat ccatctgtca ctgatatccg
     3301 ggagcaatac cctctccgat tggaggatac cattgagctt gcagcgcaag cgcgtatccg
     3361 tcatcccgaa gtacggggac aaattcaagt catgtccacg gattttctgg tggacaccaa
     3421 taagcctgag cttcccagaa tggcgattca ggtaaaaacc tcttcagatc tttcaaatcc
     3481 tagaacaatc gaaaaactgg aacttgaacg gcgttattgg gcgttgaagg aagtgccctg
     3541 gtatttgctg acagaaaaac aaattcccaa gaccgtcacc aaaaatattg cctggctgta
     3601 tccagcgcaa ttggttctgg atgggatcga agatactctg catatggcct ccctttatct
     3661 gagcttcttt ataaatcatc cgactttgct gatttctcag gttgcaatga tgcttgatca
     3721 agcctattca ctctctccag gcgaatccct gcaaaaaatt cgttcgctgt tagccttgag
     3781 ggttttctta tttgatatca gaaggccttg gtcaacactg actgtggggg agttacaagc
     3841 atcttcagac attgattcat tgaggaatta ttatgttgcg aatcaatgat gtcgtgatat
     3901 ttggggaggc tcggtatcgt attcttgatg tctcagatat tcgatataca tggattaata
     3961 tcgattccga caaagcattt cctgaacggg tttctctggc agagatggaa gacttcatcc
     4021 tttctgagac gttaaaaaaa attgatgatc cctattcgca tcttgctgct cagttcccgg
     4081 aacacggctc agtagcacag caaatccggg acaagcgtat ggccgttatt gagcctttaa
     4141 tacaccaacc ggatatctat tatcgcagcg gtcgaggcgc actggttcag caggttgtta
     4201 ctgaatctgg aacggctaaa aaaacaatat atgcctatct tcgccaatat tggcagcggg
     4261 gttgcactcc gaacgcgctt ttgccggact acgataaatc aggcgggcga ggaaagaaac
     4321 gtacagcttc aggaaaaaat taggccgtcc gagaagtata gcgccaggta cgggcgcaat
     4381 tgtagatact agtgttgaac gcatgtttcg cattgtgctt gatcgacact atctgacgga
     4441 gaagaatcat tctctaccct atgctcatcg acgtttcgag gacatgtttg aaacagctca
     4501 tcccgatgta ccgaaagaaa actttccgac agttgctcaa ctacgctatt tctacgagcg
     4561 ggaatatgtc cggcctgaac gtatccggct gagagctaat aaaatcgaat atcaaaagga
     4621 catcaggccg ttacaaggaa cagccacaag cggagttcac ggccccggtg cacgctacga
     4681 gatcgacgcg actattgctg atatctatct gctttctgcc gacagacaaa agattattgg
     4741 ccgaccaacc ttgtacgtgg ttgtcgatgt ctatagcaga ttgattgctg gtttctatgt
     4801 gggacttgaa aatccctcct atgtgactgc gatgttggca ttggtgaacg ccatgatcga
     4861 taaatcttcg ttatgccagt ctttcggtta tgacatagag tctgaagatt ggccgtcgat
     4921 tgggctgccg gacgccattt tggctgatcg cggtgagttg ctgggtcatc aaattgaata
     4981 tctggagcag gcctttggtg ttcggattga aaatacacca ccttatcgtg gggatgcgaa
     5041 gggtatcgtt gagcgacatt ttcgtaccat tcaagcggac ttcaaaccgt ttgcaccagg
     5101 agtggttgct ggaaccacca ttaaaaagcg gggcgggaaa gattatcggt tggatgcaac
     5161 acttacattg gacgatttca ctaaaataat tatcggttct atcctgcatc gcaaccagag
     5221 ttcggtattg gtcaagtatg accgcgatcc ggatatgcca gatacactcg cacctgtacc
     5281 gattaatatt tggcaatggg gtattcaaaa tcgtagtgga cggctgcgta acacatcgga
     5341 gtcggcgttg aagttggcat tattgcctcg tcaaaaagta acgctttccg attacggcat
     5401 tcaatgcttt ggtgcctttt atacctgtag ggagctgctg gcgtctggct ggctccatag
     5461 aaccgggcaa cagcgacctg gcccctttat ggctacgtat gacccctcgg tagccgacat
     5521 catttatgtc ttcccagatg caacaaaatc aggttattgg gagtgctctc taaccgaccg
     5581 ctcaagggaa tttaggggcc ggtcgatgtg ggagttatgg gacagccagc agcaacaacg
     5641 aaaatcaaca gcggcagcta aattgaaaga gagggaaagc aaaagatcac tggaaaatgt
     5701 gattcaggaa accatccaaa acgcggaaaa gctacgtcct tccaactttg gtgaatcaaa
     5761 aacagagact ttggcaggca tcaaccaaaa ccgacgggaa gcacgcgagc aggaacgcca
     5821 taaacgtcgt gaagattgca aacctactga gccaaagccc aaagcggatg tcaggtattt
     5881 gattgatcag cccgaagacg ccgcattccc tgattttctg gatgacctgt ttggagatga
     5941 tgaatgacac tacccaaagg catggtgcag gcgatttata atgataccgg gatcagtcag
     6001 tatcagggaa accctctcat tgaggctttg ccgcctatcc tggaccggcg tcagctaaag
     6061 gacgggttgt cgggtcaaat tatgtttcgc ccaactgacg tttatcttga tggccagacc
     6121 cgtgttcatg tcatatctca attactcgac aattttttcc agccgctatc ccgtcacatt
     6181 gagctggagt caaaattatc ggtcatgctt cgacaagggt atgtcggaag aaatctggca
     6241 acaggtgaac tgaatgccca catccagaat ggttatgagc gtgtcatgca gggggggttg
     6301 gctgttttcc ggttcgagca tgtggaatcc accgctaagg aaggtgcgaa caagttcctg
     6361 atatgagatc atcatattca tccggagcgc atcccagagg gacatcatga gccatcaact
     6421 caccttcgcc gatagtgaat tcagcactaa gcgccgtcag acccgaaaag agattttcct
     6481 ctcccgcatg gagcatattc tgccatggca gaatatgacc gctgtcatcg agccgtttta
     6541 tcccaaggcg ggcaatggcc gacggcccta tccgctggag accatgctgc gtattcactg
     6601 catgcagcat tggtacaacc tgagcgacgg tgccatggaa gatgccctgt acgaaatctc
     6661 ctccatgcgc ctgtttgccc gattatccct ggatagcgcc ctgccggatc gcaccaccat
     6721 catgaatttc cgccacctgc tcgagcagca tcaactggcc cgtcaattgt tcaagaccat
     6781 caatcgctgg ctggccgaag caggcgtcat gatgacccaa ggcactttgg tggatgccac
     6841 catcattgag gcacccagct ctaccaagaa caaagagcag caacgcgatc cggagatgca
     6901 tcagaccaag aaaggcaatc agtggcactt tggcatgaag gcccacattg gtgtcgatgc
     6961 caagagtggc ctgacccaca gcctggtcac caccgcggcc aacgagcatg acctcaatca
     7021 gctgggtaat ctgcttcatg gagaggagca atttgtctca gccgatgccg gctaccaagg
     7081 agcgccacag cgcgaggagc tggccgaggt ggatgtggac tggctgatcg ccgagcgtcc
     7141 cggcaaggta aaaaccttga agcagcatcc gcgcaagaac aaaacggcca tcaacatcga
     7201 atatatgaaa gccagcatcc gtgccagggt ggagcacccg tttcgcatca tcaagcggca
     7261 gttcggcttc gtgaaagcca gatacagggg gctgctgaaa aacgataacc aactggcgat
     7321 gttattcacc ctggccaacc tgtttcgggt ggaccaaatg atacgtcagt gggagagatc
     7381 tcagtaaaaa ccggaaataa cgccagaaat ggtggaaaaa atagcctaaa taggctgatt
     7441 cgatgtgttt gcgggaaaaa aatcggccca gatccgcgaa attttaatca gcgagtcagc
     7501 ttgggaagaa atgacctgct tattcgcacc ttccttagcg gaaaatgcaa aacacggcac
     7561 cgctaatgcc gatgagccag tatctgtcct cgataacgac tgtcagacaa ccagtgggat
     7621 agacgaccag ggcaacagca ttgatggagg caaagcatta cagatagccg atcacgagcg
     7681 caagttagtg gcggttaccc atggacaggt cattacagaa gctctgaacg ccacctctga
     7741 ctttctggat acggattgcg tcatggaccg cctcgggata tcgtacgagg aggctgagct
     7801 tcgttcttcc ggcgcgatgg aactgcataa tgcgcttatc gagtggtcga aagattgagt
     7861 ttgcactcag caaaagtaac tttttaaaga tagtaaaaag gttgaaatag gcggtctaat
     7921 gaaaattaat gaacaattac taagcgcact gcttgcggct cttgagtgga ttgatgccgt
     7981 tccttccgat acggttttgc ccgcaatgcc aggatttgac cgcgatgaag tgaacgagtt
     8041 gatcgcaaac gctcgcaaag agctgcaaac agagacgaac taaacagggg cgctggtctt
     8101 ctcatagcag gacaggatac ctgtacctgc tatgtatccg gcagcgtgaa acagcacagc
     8161 acctgaaaag taacttttta aaccccgaac atttgtctat ctgcgtacgg ggatcaacat
     8221 gacgggctga gcgtctatga tttgcacaat cagataaaaa tagtttcttc cttcccccgc
     8281 aagctttgcc tccttccccg aacgcaggtt ttatcaaaaa gtaacttttg aaagagtggg
     8341 ctcagcactg aaaaaagtta cttttctgtc ctgagaagcg tgttcaagtg tcgttatcac
     8401 cctcaaaaaa gtaacttttg acgatttatg tcctaaaaat caatgagaca tgcatcgtct
     8461 gtaatcacct tcactgttcg tatctccttc aaaattatcc aaaaattatg atcccggcat
     8521 accactgaaa aaattttctt cacataaaca ccgaaatccg gctcctggag cccttgccac
     8581 agaagaatca tgtgtaaaat ttttgccgtg aacaaaaaaa gtaacttttt tcacgccaaa
     8641 gtgaaaatag gggcttgatg gagcgttttg agaatgtatc ctgggtctaa caacggcaat
     8701 gaccgtttac ccacatacaa caggaagagg aaaattcaat gactactgca actatggcaa
     8761 ctccagctaa agccaaaaac gaaaatgttt ctctgcgtac cttcttagaa aaaaatggta
     8821 tcggtggtcg tctgggcaat ggtcttgtta tggacccgac gcatctgaac atcatcctgg
     8881 ctttaacaca cgtaccgctg gcctgggtga ggcttactgg gaactcccgg aagttaagga
     8941 ccacctggcg cgtctggctc agcaatatgc cgatagccct ctggaaatgg cccctatggt
     9001 tgtccaggtt cgtgatggtc aggttgtcat tcgtcaggga cactgccgtc accgtgcaat
     9061 tccctggcaa ataaaattcg cgcagaacgg ggtgagggcc cggttgataa aattcgtgtt
     9121 gacgaattcc gtggctctga cagtaaagca gaacttttaa tcttaaagga aacgatcaac
     9181 ttccggtctc gatcgttgct caggctgagt ccatgtatcg catgcacaac agcgcagaag
     9241 agcctatgag catcgaagag ctggccgcag accgtaaagt ctccgtaacc catgtccgta
     9301 aattgctcaa agttcacacc gccccggagg cgttaaaagg tctgatcgtt aaaggtgtag
     9361 tagcatacta cgcagcactc gacgtgatgg agaaataccc ggataactgt gtcgctatca
     9421 ttcaggaagc gtttgataag tttggcaaag ctaccgacaa aaccattggt caggtccttc
     9481 ttgctaagcg tacaggtgaa aacgacacta atggtgaatc tgatggcaat gtgacaacca
     9541 ttacaacgac tgatgcaggt aacggatcta atagtgcctc tgacgcggct gctggtgtca
     9601 ttgaaagctc tgcaggcaat gatgcaggcg ttgcgggtgg cggttcagaa gaaggggaag
     9661 gcggtgaaaa atccgaaccg aaacggaccc ctgcggcgaa acgcgaacct aaacaaaata
     9721 tcaaatctca gccgtcggtg ttcgacgtgc tgccgaaaaa aatctccaaa gagattgtag
     9781 ataactctct tgatgttatt aaccgtatcg ttaccgaagc gaaagaaatt ccctttatgg
     9841 aagacggtgc agaggttctc gctaaagccc agtatcaact gacgttaacc tatgaagagt
     9901 ttttgcagct gactgcagcc aaagacagct acgataagca tctggaaaaa atccagaaaa
     9961 aaactcagag caataatatt taaggcgtaa ccggggagtt ttccccggct tgcctcatga
    10021 tttgtgaatt ggtatagaag gggataaaag atggttcttt ttttaaatta tcttacaaat
    10081 atcatgcgaa gatttttaga tattgtctgg gtaaagaccc acatcgcttt atcgtggtgt
    10141 taatcctgag ccttacactc ggctttgttt taatttactc ataagatata ttcaccgctg
    10201 gttgcgtcgc agggatttaa ttgcgcgtaa gcgggagaaa ggctgagcag gaattttatc
    10261 ttttatgagg ctcgataatc ttttagaaat tccagaaggc taaattcagt tgcttacaac
    10321 ataaaatagg ttgaatgatt tattggttta aatacattgt tattgtaagc ttctgtttgg
    10381 ccaacaaaag atcattttct aataatcttg ggtgatttta tggtatttat aaagggtttt
    10441 ctttttttta ttattatggt gctattggtc tacggagtca cgggattaac cgccaaagaa
    10501 tcaattgtgt ttactgcgtt tggttttggg atttcagcga tattatgttc attcattggc
    10561 attatggttg tgttggttgt gactatgtgt ttgtttgcat tcgaagaact tggcgcgttg
    10621 cctagattat tggtgcccag ataattttaa ttgctttgtg gaaccttata tttaccgtgg
    10681 ttttgccgga tggaaaagca cgcaccatac tcggttttga tctctacaat atttcatcgt
    10741 atttgcttta cggtatgacc gtccttttag gtataggctc ggtggcaatg ctttttacaa
    10801 aaataactcc tgaggctaat taatgaaagg tatcaatcaa tccaatggta accatttaaa
    10861 gtttctgtat ggagtgacct ctacagatcg tcttattcag cacgaacatg ccgataaatt
    10921 cattgatagc tgcattaaaa atattggcag cattcataaa atgtccctgg cttgttatcg
    10981 ggctggtgga ccattaactg agctggtgct ttttacggtt cggacaaaac attctcaatc
    11041 accattggcg ttggcgatgt agatgtttcc atggttaatg aagacgatgt ccgaatttct
    11101 cacaaacaaa tcactttgcc tgatacgacc gatacattaa tactcgttac tcgcattgca
    11161 agacgtagtg ggctgaagcg atgttacctg aagcagaaca atcagcacag ttttagactt
    11221 gtttgaagat tgccttaaac tgaaggagga agtatgacgc agagtgaaat tatttaattc
    11281 tttttgggat tgggaacttc attattaaca agtaacgcag ctgtaatatt ttatgccttg
    11341 cttgtggtat tggttcttgg cgctgttttg tttaaggact ttctttactg acaacatttg
    11401 cttccggact ggctggtatt gcactcctgt gtggagttat gtctgtgctg tggttttggt
    11461 tttggcaagc gaccagaagg aacaggactg gcaagacttt gcagtgagca ttgcaaagtt
    11521 atagaaaaaa gagaaggtgc taccacgacg ggagtgggtg tttcactaaa aggtcaggct
    11581 ggtgttttta ttggaggtga acctgaccag acagggtatc tctgtgacga tggtgtaacg
    11641 tactggaaga atgaataaat accgtgttgt caattttcta aacagtaaat ttaataagag
    11701 gtttacatga atcttgataa aagcttaccg ctttagtaat gaaaatgttg aggataacat
    11761 gggggttatt accaaatatc tcaagcaaac agaagataac gctcttgtat ttattattgg
    11821 agaaacaggg tctggtaaat cctgttggct gaacttgagt ttccggatgc tctctacccg
    11881 actgctcaac aatttgaaga atgtgatcac attcggaaat gttcacaggt tttgatgtag
    11941 tgattgatga catttaatga gatggtcact cctccttccg gtactatgct gaggacaggc
    12001 tttcattcgg agaactatca tggaaaacat tgcgctcatt ggtatcgatc tgggtaaaaa
    12061 ctctttccat attcattgcc agggattcgt cgcgggaagg ctgtttaccg taaaaaattt
    12121 accggccaaa gtgatcgaat tttggcgaca tgccgctaca accatcgcaa tggaagctgt
    12181 ggcggttctc acttatggca cgcaagttgg aagagttggg gcattcccca aagctgatat
    12241 caccacaatt tgtcgcccgt cgttcgttaa aagcaataaa aaacgacttg tcgacgcgaa
    12301 gctattgtga agctgcatcg cgtccgtcta tgcgtttgtg cagcccagaa cggaatctca
    12361 gcaggcaatg cgggctctgc atcgtgtccg tgaatccctg gttcaggata aggtaaaaac
    12421 aaccaatcaa atgcatgctt ttctgctgga atttggatta gcgttcccga ggagctgccg
    12481 ttattagccg actgagtacc attcttgagg ataatagttt gcctctttac ctcagccagt
    12541 tattgctgaa attacaacag cattatcact atcttgttga gcagattaaa gatttggaat
    12601 cccagttgaa acgaaagttg gacgaagatg aggttggaca gcgcttgctg agcattccct
    12661 gcgtcggaac actgacagcg agtactattt caactgagat tggcgacggg aagcagtacg
    12721 ccagcagccg tgactttgcg gcggcaacag ggcttgtacc tcggcagtac agcacgggag
    12781 gtaggacgac attgctggga attagtaagc gaggtaataa aaagatccga actttgttgg
    12841 ttcaatgtgc cagggtattc atacaaaaac tggaacacca gtctggcaaa ttggccgatt
    12901 gggtcaggga tttactgtgc cggaaaagca actttgtcgt cacttgtgct ctggcaaaca
    12961 agctggccag aatagcctgg gccctaacgg cacgacagca aacttatgta gcataacggc
    13021 agaaatacac cggtttaaag aattactgat ctggttttgc gaatactgat attgatgata
    13081 ctaacggccc accggcctgt tgaggaacct gtaaaacgga aaggctcatt gaagccgtat
    13141 attttctgga ggttcatcag gcgcggaact catcaaggcg cgggaataaa atcccattca
    13201 gacgccggat agattcaagc aagccaactt gtcgtcaaaa tcggtgttgc aaaaacggga
    13261 gtgaccatag attccgtttt ctgaggcgac ccctatctgg atagcaacct gttttagctc
    13321 aggagggagg tgttccagat tgatatgatt atcacccgaa atgtcatcat ccggactttc
    13381 gaagagccag ccgtaactca taaggtctcc tgttctattt cacaaatttc cagacacctg
    13441 acggtacccg gtcatacaac tttcccatcg tcatctccgc cagccggtga tcaaccgcgg
    13501 cattgaaatg ctcaagctca tcatctgaca gagaatattt atttttttct ataatccttt
    13561 ccagggtttc cttcgatgta cagcgccgta gtcgtaaaat ccattcctgt ttcgtcattg
    13621 gttttttata tccttaggtg tcccggtagt ttcattttgg aagaagcttt cctttcagcc
    13681 agttatgagt gaaccatttt gcatatatga tgtaacccac aaaagttaag agtgcggaca
    13741 gactatatat ccggagaaca ggtaccacgt gatgaaaacg tatcatctga ccggattcat
    13801 ctgccagact cattaataca ttgctgtatg tttcagtctg aaaaaactcg tagtaaggta
    13861 ccatcacaac atgaagaaaa aataaattaa gcagatacgt cagagaaaac gcgtgttcct
    13921 gcccgttata gggcgcatac tgcgcaaagg cgaacatcca tccggtgaaa agcagaaaac
    13981 acatcgttaa atacaccacc acccatatcg ctgttttcat cactgcccct cagttatata
    14041 atttttctgt aacgcaaatt tcttcaggcg ttatggcccg tgccgttctg cttcagataa
    14101 tcactgatgc tcaggccgga caagcgaatt atatccgaaa tctccctgaa ctgctcctcc
    14161 cagccgtcct gcagctccct gattgccgcg atctggaaag caacactgaa aggcgttctg
    14221 cccagtttct cggaaagcca gaacagatgc ctgccaatct cttcgtccgg taccgaatcg
    14281 agcgcatcac tcagtaaggt tttttcgtct tcctgccagg gatgaccggc tcgcggaaaa
    14341 cgcggatcag gctggcggtc ttttttctcc cttttttccc gtctggcaac ggccggcgct
    14401 tcgccttttt tcaagccgac gcgcgctttc atggcgccga tggcagcgac ggccagtacc
    14461 agcgtttcac gctcctggcg cgtgagcagg ctgtcctcgc aaatcagggt gttcaggtta
    14521 tcgatcagcg tattcagccc gggttcagtg actttcattt tatgctcctg ttccttgtgt
    14581 ggtggcgatc agtcccggct ctcattcacc tgaacgatga ccggcaggcc tgcatcaaaa
    14641 caggcctgat accagctggc cacctgcagg ggatcgccct cttttatccg gcgtatgccg
    14701 ccggcatccg tcagctgcag gcaggtggta ccgtccagac ggatcacgta ggccgcttcc
    14761 ctgatggtgt aatggccgtc atccagctgc agctccaccg cgtcaccggc agccgtctgg
    14821 cgtaacggca gacgccggac gtcggtcagt cgttgtcgtg ccgtttcagc ctcgcgttct
    14881 gcctggaaga gcggttctgc aatgccgcga ccggcctccg tcagctcgac ggccagctgc
    14941 aggttcggcg cgcgcagggt gcgcagccag cccgcggctt ccatgcgccg gcaggaggcg
    15001 cgcaggttcg gtccgtacac cggggcgtcc ccgccctgct ccagcacccg ctcgatatcc
    15061 cgcgtcgcca ccggccccgg acgtttcgca tcgagggcgg ccagcacaat cagtacccgt
    15121 cgctgcagcg gcgacggcct gcgggaggtt gttactgctg ccatgaacgt tgttctgctg
    15181 tgggagcgcg caggagcatt ccggtgaggc gcagatggtc cctgtcggcg acgtcttccg
    15241 gggcacggcc cgccatcgcc aggtggtacc agagttcgat cgcgctgcgt gcccaggcaa
    15301 tctccgcatc ggggtcattg cagtctgcgc ggccggctcg ttcgagacac ccgttaatga
    15361 agtcttccgt gtcggcggtc atcgtttcat agctgaggcg aaagtatact ttttcatcca
    15421 tcctgcacgc tccgtctgat aatgtctggt taagtgtaaa gtcatatcat gtatagttta
    15481 ttgctaatca attaaacatc atatcagata tgattttatt attaatgata aatatcattc
    15541 ttagtatgat tttatgcatg ttcattaatt atcatatcta ttgcggattt tccgcctcgc
    15601 agatccggtt tctggcttaa gcggatccgc acgtcttctt ttatgaatgg tagtccccct
    15661 ataccgtaat ttttctgccc ctctgtgcat tacaagccgt tgtttaacat tctcaatcgt
    15721 ttatgctttg agggtctgtc agcacagcga cagatacatc gtccagccgg gcattctgtc
    15781 cgggggacaa aacatcaaaa cgatggagat taagcctatg gcttatgtta atccttatat
    15841 gaaaggtggt ggaaaatatg agttcaaaat caggggtaaa cccaaacgac gaagttaatc
    15901 agactgttga aacttctcta aatgcaggca tgaatgaaca ggacgtggca tctctcgata
    15961 aaatcgggaa gttacaggac gaacagctcc agcggtgcgg aatgactgtg ccatcaggaa
    16021 ctgaggtgtt ccggcttcag ctcggtagtc acggcggaag cagtgtcttt ttcaatcgta
    16081 atggcgagga ttgccgttac agtcttaatg atggtgagaa tggctctatg tacgtggcca
    16141 aaactcccga cacggcaatg aaggaagttt ttcagcataa aacagggctc agggaatcag
    16201 atctcgataa ttacataatg ggtacagtag tcattgagaa agatattcgg gtccttcagg
    16261 tcagtaagct gattaaatgc agtgatttaa ggttgaatga tgtaacaact tcaacacgtg
    16321 cagtgactca tcaactggct gaaaaagttc attcagcagg gtttgatgga atggagtttc
    16381 cgtcaaatgt caccagtgac ccatgccttg tgctatggca tgacgatccg gccggaaccg
    16441 ggatggccat aacccggagc cagacaagtc tcagtcagtt tgagtatcag ggtaaggaag
    16501 cggcagatat tcttgtttat gacctgggaa ttcctgttga ggaataattg ataaaggggg
    16561 ggcaagcacc ccctttcatt aaacggcgtt ctgtgtgcca tagttgcgag ccagccggcg
    16621 taattcattc atcacttttt catccggatt gcctttcaga acctcggcga cggtaaacga
    16681 acgccctgca gggttcagcc catccaggac agtatttctc tgttccataa agaaagaata
    16741 cttcattcgg tcactgaagc tgctcagcat agtcagcagt tcggccacac cccggagcac
    16801 gcctttgtcc gagatccctt cctcatcagt aaactgaaac accgggtagt aaaactcacc
    16861 gtcaatatca agagcaagta actgatcggt atctttccag gttttaactg tgggtttact
    16921 cttgcccacc atttctgcag ctttagctga ggtgtaaacc ccgccgtcat tttccagtct
    16981 ctgaaggaaa agggccttac tgtgtaaacg tcgctgctga cgtttttttt caggcgtcag
    17041 gctgttaact gcgcgatttt caagtaactt caggatgaca tccatggtaa aaaccgcatc
    17101 ggtattcccc atactttcag gagcaatcgg tgttttacct gaccgaactt cctctaccag
    17161 atcctgaaaa aaattctcaa gacgctctgc agcaatgctg ttgtccaaaa aattatgcat
    17221 agtggaggaa cgatcattac cgtttcgttt ttgagttgat gtgttcataa aacctccttt
    17281 tcgatttcat gctttataga ctacgttaaa tcgttaagtt gtgcaagttt tgttctcacc
    17341 ccacctttta tagtttttaa ctattgatta ttgaattttc ttcggtatta attatttcgt
    17401 catttgagat ccgaaaaaag gttgttccgg atctgccgga gccctaccgg cgctcagtgg
    17461 ccaagaaaca caatatgcag cggtgttatt agcttctttg acgctatatg ttgtatccct
    17521 cccctgccca gagatcggtc gctcagcacc agaaaagggc ggtgtggtta ttccctgacc
    17581 gtggtacact tccggaaact tcgtaaagcg cgaaaagtcg gatcaggacg gaacggccgt
    17641 ccggtaattt aacggcgtgg ctgtatggct gcttgttatc tctaaggtga ttattttgta
    17701 tgtgaatttc acggtgtgaa atgaatggcg acataacagt atgtttcagg cgggcgtgag
    17761 tcagctgcat ccttacgcta tactgatatg catatcatca gtatgtattc cggagtgcat
    17821 tatgaagcag cgcatcaccg tcaccataga cagcgacagt tatcagttac tgaaatccgc
    17881 agacgtcaat atctccgccc tggtgaacag ggccatgcag aatgaggccc gtcgtctgcg
    17941 tgccgaacgc tggcaggctg aaaatcagga aggaatggcc gaggttgccc gctttattga
    18001 gatgaacggt tcattcgccg acgaaaacag ggactggtga gatgcagttt aaggtttatg
    18061 cctataaaag agagagccgc tatcgtctgt tcgtggatgt gcagagtgac atcatcgata
    18121 cccccgggcg acggatggtg atcccgctgg ccagcgcccg gctgctgtcg gataaggttt
    18181 cctgtgaact ctatccggtg gtgcacatcg gggacgacag ctaccgcctg atgaccacgg
    18241 acatggccag cgtcacgtcc tccgtcaccg gggaggaagt ggccgatctc agccaccggg
    18301 aaaatgacat caaaaatgcg ataaacctga tgttctgggg aatttgacag cctccccgcc
    18361 ctgaaagaca tcgaggatgt caaaacgaag tattgccgca gagcttaacc ctcagcatga
    18421 actgctctcc ggagcggatg ccctgcaggc tttcgcgggg tcagcttaaa cgaacggttc
    18481 acgcaaaaac cctaaggaac aaatatggcg gacggaattt cagtctgggt accggtgatc
    18541 tccacgttat cgggagggat actgaccgga agcattgccc ttctggtgag ccggttgaat
    18601 catcgttacg ctggcgaacg tgaggcttta gcggctgcag aacggcatcg ccacgagcta
    18661 aagattgctc aggaattact ggataaagaa cgtttattca tagcaactga gttgattttc
    18721 ttactggaac aattcgcgga aggctgcgct cgtatggcca cagactgcgg cgagcctgat
    18781 ccgcagggtg tatacactcc aacggaaaat cttccggagc tgataatcaa gaatatttcg
    18841 ggtgactggc gggcactccc ccccccgatt atgtaccgga tccatgaact tccggtactt
    18901 cagaatgaag tccggagaca tctcgcggct tattatgagc agtactggga gcctccctat
    18961 ctctccccat attatcggga acgtcagttc cattatgccc gtctggggat aaaggccgtt
    19021 attctggccc agagactgcg aaaactcgtc ggtctgcctg gaacccgcct cgatgcaacg
    19081 gaatggtctg cacaactcgt cctctctagg gtgtggcgga aaaaacgtaa agaaagaacc
    19141 gaagctaaaa ttcgtcgtct gcgtaaaaag actggggaga attcatgata atgcctacca
    19201 ttcaggggca gagagtcaca catacctctg ctcagttgcc ggtggccatt gattatccgg
    19261 cggcactggc gttgcgtcag atggcgctcg tacaggatga actgccgaaa tacctgctgg
    19321 cgccggaagt cagcgccctg ctccattacg tgccggatct tcaccgcaag atgttgcttg
    19381 cgacgctgtg gaacaccggt gcgcgtatta atgaagcgct ggcgctaact cgtggggatt
    19441 tttcgctggc accgccgtat ccgtttgtgc agctggccac actcaaacaa cgaacggaga
    19501 aagcgaccag aacggccggc cgttcacccg ccggtagtca ggcgcatcgc ctggttccgc
    19561 tctccgatca ccactacgtc agccagctgc agatgatggt ggccaccctg aaaatacctt
    19621 tggaaagacg caacaagcgt accggcagaa cagagaaagc ccgcatctgg gacatcaccg
    19681 accggacagt acggacctgg attggcgaag cggttgaagc ggccgccgtc gacggggtga
    19741 cattctcggt gccggtcacc ccgcatacgt tccgccactc ctacgcgatg catatgctgt
    19801 atgccggcat accactgaag gttttgcaga gcctgatggg ccacaaatcg attagctcga
    19861 cggaagtcta tacgaaggtg ttcgcacttg atgttgctgc gcggcatcga gttcagtttc
    19921 agatgcccga agcggatgcg gtagccatgc tgaaagggaa tatttaagta cttaggagaa
    19981 tgatgctggc gaacgtcctg ctcgccgggg aggtctgtca gacgttatct ggaccagctg
    20041 acgggaatat ctgctctgta ttcctcatac tgctcataga tcgcatgctg aagcatcgta
    20101 atacgttctg acaacctgtt ggcgtccgac atatgccgcc attccccctc aatagtggtt
    20161 ttctgtccat ccgggagatt gagcgtgatc aatacctttg tatcacgaat aatcaccccg
    20221 tcagtgaaag aattaagacc actccttacg gtattatcta tctgtatagt ttcaagtttc
    20281 atcttgttac ctcctgttga ccggatccca agcatagata tctgaattca aattgcctag
    20341 tgaaatgtct ggatatgccg catttttccc cttatacagc gaagctggcc aaaggccagc
    20401 ccgcttggat ttatcgcttt tgccagtaga tcagcatggc aaggaacagg attgttgccc
    20461 cctgagaagc ggtcaggaaa gtttccagca atgacattat cgtaaaactc cgcattatta
    20521 atttcaggtg tgtgattcag gggccttagt ccccctttta caggacgtag tgttctgtca
    20581 cgacggaagc cagggttaat aaaaacgatt cgaatatgtc tgcagggacg atagaaatct
    20641 tcgtgcgggt tgtctcgctg tagccggctc tggagagcga ctcgggggag gagtagtatc
    20701 ttccggccac ggatatgatc gagccagcag tgctcgccgc agtcgagcga cagggcgaag
    20761 ccccgagtga gcgaggaagc accagggaac aaaacttata aattctgctt acgctcaatg
    20821 cctgaaaaat cacctcccct cggggttatc cacttatcca cgggcatatt tttataaagt
    20881 acttttttat tctttttctt tattttacat cttttaggga gcctgaaagc cgcgtacagt
    20941 gcggcctgag agggggcctg tatgggcaac tggtaaacat aatatgggaa attaatcacg
    21001 tatcagtggg ttttgtgtca acaagctatg ggatacgcat caacaagcta tgggaaagag
    21061 gtcaagttca gttctcaatt atccacttgt ggataaagtg cagatttttc cggtggataa
    21121 gtatcgcgat agcttgcaat ttctgttttc actgtcatta tgggtgggta aaaatttacc
    21181 cataggcatt gaaatggata ctcaagcact cttgccagct actaaaacgt ttaaaaaacg
    21241 cgccagtata aagcaatcta acgaattgac cgaagctgca tattacctgc ctcttcaggc
    21301 aaaacgtgtg ctgtggttat gcctcatgca ggcctatttt aatgacagcc aggaagatga
    21361 ctctgacgta ttgccgctct tcaaaatcag cgtttccgat tacgtcaaat acttcaatgt
    21421 cgctacgtct gtcgccagtc gtgatgtgaa ggctggggta aatgctctgg gcgaatcaac
    21481 ggttaccttt tatccaaaag aaggtgagtt tgaagaagtt aaacgtccgt ggctggctga
    21541 agcaggaatg aagcgaggcc ggggttcttg gcagattgaa tttaactaca aggtcatgcc
    21601 attcctggtc ggcttaacct cccagttcac tacctattct ctctatgact gtggccagct
    21661 taatagtgtt cgtgtcatcc ggctttatga aagcctgtgt cagttccgga gcactggtgt
    21721 ctggatcacc acacatgact ggttatgtga aaggtttatg ctccctgcct cgcagaaaaa
    21781 caatattgct gaaatgaagc gtaccttcct ggaacctgct ctgaagaaaa ttaatgagaa
    21841 gacgccatta aaggtaacat ataccactga agaagatggt cgcttgctgt ttaattttct
    21901 tgataaaaaa caatagtctg taatttttat ttcctccccc cttagtttgt tgctgacata
    21961 tggggggata ctgaacttgc tgtgtttccc atagtgcttg cctaacttga cctgtttccc
    22021 gcaatcgcgg ctgtctgcgt agttgacctg tttcccacag tccgggccgt ctgcggagtt
    22081 gacctgtttc ccacagtccc ggtcgtctgc aaagttgacc tgtttcccac agtcccggtc
    22141 gtctgcaaag ttgacctgtt tcccacagtc cgggccgtac gcggagttga cctgtttccc
    22201 acactcccga ccgtccgaga agttgacctg tttcccatag tccgggccgt ccgagaagct
    22261 gacctgtttc ccttagtccg ggccgtccgc gaagttgacc tgttccccac actcccggcc
    22321 gcccgcgaag ttgacctgtt tcccacagtc cgggccgtct gcaaagttga cctgtttccc
    22381 acagtcccgg ccgcccgcga agttgacctg tttcccataa tccgggccgt ccgcgaagtt
    22441 gacctgttcc ccacactccc ggccgcccgt gaagttgacc tgtttcccat agtccgggcc
    22501 gtccgcgaag ttgacctgtt tcccatagtc cggagcgtcc attaaagttg acctgtttcc
    22561 cacagaggat ggaaaactct tcttgtgctg agcgtaagag ctatctgccg gaacggttcc
    22621 tcttcgcttc ctcgccagtt cgctcgctac gctcggttac atggctgcgg cgagcgctga
    22681 tacataaggc tcagcattgc actggtcgta actaaaatca gaatccttct gaatgactct
    22741 cctgtcttgc aagttgaata cctttctcaa agcccttttg tatgagttgc tgttgatggt
    22801 caaaagtgcg tctgcgtgtt gctgcagtgt gatttagtag cacgcccgtc gagcttcatc
    22861 ccccttctgt tgagagcgaa atcaaaacaa tatgattttt ttcttgcaac atgacacttt
    22921 ttgttcaaaa tgacaaaaaa cgtcatgagg tgataaatgg acaatattga gcagttacgg
    22981 aaagtcgcta cacgtgcagg taagcttctg acatctttga gcgaaagtat ccgacagcaa
    23041 aaagaggaat tgaagcttac cgagttctat caggaataca gcaaagccgc tctgtataag
    23101 ctgcctaagc tcagtaaagg cagtgttgag tatgctgtgt ccgaaatgga agccggtggc
    23161 tacattttta aaaagaaacc ttctggtaat acgatgaaat acgcgatgac gattcagaat
    23221 gtcatcgatc tgtataacca tcgtaaagta ccgaagtaca gggatcgctt cgataaagcc
    23281 tttacgattt ttgtatgtaa tcttaaaggt ggtggttcca agacagtttc taccgcttca
    23341 ttatcacatg cttttcgagc tcatcctcag cttctgttcg aagacctgcg tattctggcc
    23401 atcgatttcg atccgcaggc atctctgaca atgttcctga gccatgagaa ttcagtgggc
    23461 ttggttgaaa atacggctgc tcaggccatg ctccagaacg tgtctcgtga agaattactt
    23521 tccgatttta tagtaccgtc tattatccct ggtgttgatg taatccccgc ttccattgac
    23581 gatgcattcc ttgctgaagg ctggaaggga ttgtgtgaag aacatctgcc agggaaaaat
    23641 attcatgcgg tgcttaaaga gaacattatc gacaagctcc agcatgacta cgactttatt
    23701 ttccttgata gtggtcctca ccttgatgcg ttcctgaaaa actgcattgg ggcggcagac
    23761 ctgatgttga cccctcttcc accggcgacg gttgattttc attcttccct gaagtttgtg
    23821 gccagcctcc ctgccctcat agattccatc gaaatggatg ggcacacctg caatctcatc
    23881 ggtaatgtcg gcttcatgtc caagatcctg aacaagtctg atcacaaaat ttgccatagt
    23941 caggccaaag aggttttcgg tgccgatatg ctagacatgg ttctgccaag actggatggt
    24001 ttcgaacgtt gtggggagac ttttgacaca gttatttcag caaatccagc aacctatgat
    24061 ggaagtacag aggcactaaa aagcgcaaaa tcagcagcgg aagactttgc gaaggcagtc
    24121 tttgatcgca tcgagttcat tcgtactaac ggaggtatgt gatgtcgaat gagaaaagaa
    24181 aaaccatcgg cagacagtta aatactcagg cgtcaatgct cgaaatggct gacaccggta
    24241 gaagtcaggt atttacctta aaaaccggca ggaaggtaac gttcaggttt gttcgggtgc
    24301 ctgcatctga agttgaaagt aagaccttcg taaaccagga aaacaatgga agagatcaac
    24361 ttgcactgac cagggagtct ctgaaatcca ttatccagac gattaagttt cagcagttct
    24421 ttccctgtat tggtattaag caaagtgaaa ggattgagat actggatggt tcaagacggc
    24481 gagcctcagc aatttttgtc cgtacaggcc ttgatgtaat ggttaccgaa gaacatttat
    24541 cagctgatga agctcgccaa ctggctaaag atatccagac agctaaagaa cataatcttc
    24601 gggagattgg tctgagattg atcgctctta aagagtccgg atttaatcaa aaggaaattg
    24661 ctgaactgga gggattatct caggctaaag ttaccagggc gctgcaggcg gcggccgtac
    24721 cgcaagactt aatttctctg ttcccggttc agtcggagct atcgtttagt gattataaac
    24781 ttcttttaga agttaatgaa aaactcggtg aaaagggatt aacgcctgaa gaactcattc
    24841 agtctgtatc agctcagctc gatgcaattt tgagtgatgg cgagcgacca gaagacgaac
    24901 agaaagccag tattctgaag ctgatttctc aggcatctca ggcattgata gatccatctc
    24961 ccaaggaaaa gtcagtggtt tccccactct ggtcttttga agaaaaggac aagttcgcgc
    25021 gtaagcgtgt gaaagggcgc acgctgactt atgagtttag ccgtatgtca aaagtgattc
    25081 aggatgaact ggacaaggct atcaacgaag tccttgacag aaatttgagt caataatttc
    25141 gccatggcga tttcacatct aacttattgt aattaggcag tttaggttga gaatttcacg
    25201 gtgaaatcgc catagtttca cgccagtttc gctgcaggaa tatctgacca tcgtgtcgta
    25261 taagcaggag aaagcatctc ccgtttcatc tgccattccg ggccataccc cgccccgcaa
    25321 accatacttt acccagccct gagttgttga tcccgtccag aaccctcatc agctcagcac
    25381 tgtgagggcg tggcgggcgt tcgtcgaaca gttgcagctg cgaaactccg gagccggtga
    25441 agtcattcag cataactccg gctttggcat accggtgccc atccctccag atacgctcca
    25501 gagccgttgt agcggctgca atgatgtccc tggtgtcctg agtgggtgta agaagttttt
    25561 ccgtagccac gttgccgtag taaggctctt taatggcgaa cggagacgtt ttgatgaaaa
    25621 cggaaatatg ccggcaatac tggtgctctt tacgcagttt ttcagaggcc cgctctgcgt
    25681 gctgacagat agcctgacgg agtgactcgt actccgtgat cttcacgcca aaactgcggc
    25741 tgcagacaat ttgctgtttc gtcggagggg cttcctcaag cgaaaggcag ctttcccgtt
    25801 cagttcccgt accgttcgct caaggacgac agaaaaattt ttgcggatga aggccgggtt
    25861 cgtcagagcc agatcgagcg cggtttttat gcccagcaca tttagcttgc gtgcaatacg
    25921 gttacccacc ccccagattt cttcaaccgg ctgcagtgaa agcagtttcc gcgtcctttg
    25981 cggatttccc ctggtcagag cgagtacgcc atgaaactgt ttccactctt ttgaggccca
    26041 ctgggctgat tttgcgaggg ttttcgttgg tccggcgccc acgccaatgg tcaggcgggt
    26101 acagtcatac acctgctgac gcagctgccg ggcgaagtcc tcaagcccca tacagtgctc
    26161 cacgccggtc aggtcgagga acatctcatc aattgaatac tgttccaccc tgggggccag
    26221 ttcctccagg cagttcatca cgcgcgccga tatcgaggcg taaagttcat aattacttga
    26281 aaacgcatat attttttccg ggtatctttc gttttttatc tgaaaccacg gagttcccat
    26341 tttgatccag ggcttcgcct cggcactgcg agcgattaca ttcccgtcgt tgttgctcag
    26401 gacgactatc ggctttcctt tcaaatccgg gcggaaaaca cgttcacagc tggcatagaa
    26461 gctgttcaca tcggccaggg caaacatcag tacatctccc tcgggcggtg gatgatatgc
    26521 gtgacgacgc caaagatatc cagctcgtcg ggatcaggat aaatcggcga ccaggaggca
    26581 ttcatgggct gcagcgtcag tcgcggcgtc agcagaagcc gtttcaccgt aaactccccc
    26641 tgcatgctgg cgacaacgat atcgccgtgc cgcggctttt cagcactgtc cacaaccagc
    26701 agatcgccat tgtacagact gccgtcggcc atgctgtctc cgctggcacg caggtagtac
    26761 gtcgcgctcg gatgccgtat gcagtaatca tggagatcca gatcggactc gacatagtca
    26821 gcagcagggc tgggaaaacc gcagctggcc agatcggcaa acaatggatg ggcctgtggc
    26881 gggagttctt tcccggtgct gaaaagttgt agtttcatct ttcctcctga cactctaatt
    26941 ttactggtta tacatacagt gtgcgccggg agaccggtag agatcaaggg gtgaaagtcc
    27001 ccgaccattg aaggaccagc aatccacaag gtcctcgagt catgcgttgc ataccgcgag
    27061 gtatggggcg aagcgttgac aggggtgttg acaggccagc cattgagcca cgaaatgtat
    27121 attaaattac cgggtgccga cgttgtactg ttaacggaag gcaacatcat agggtgcgat
    27181 actgcgagtg ccacatggac ccggcggggt ctgagaccct ggcatgtcaa tacgatctct
    27241 acgcgggaac cgggagatct ccctctgacc atctgccagt gtcggagatg gcccgcaccg
    27301 ggaagacgag gagtcatagc cggtgatgta cggagaggag aagtcggact cgctcatagt
    27361 agcggcgaag caggcgaaca acccgaaagg agcggagtca gtggagcgaa ggagcggggc
    27421 caaggggaac gtggaacagc cacacatgcg ccggacacag agccgggaaa gcatgtcaca
    27481 gaggctgtca cgcgtgcggg aagctgcgaa gcagcggaag aaagaacggt ttacagcatt
    27541 gttccacctg ctgacagtcg aagcactgga agccgcattc ctctccctga gcaggaaagc
    27601 ggccgccgga gtggatggca tcaggtggat ggactacgcc ggaaacatga agaacaacat
    27661 aacagatctg caccggaggc tacatcaggg cagctacagg gcgcagcccg gcaggcgtca
    27721 ctacatccca aaagcggatg gaaaacaacg cccgctcggc atcgcctcgc tggaggacaa
    27781 gatcgtccag tatgcgctgg tgaaaatcct gaacgcagtc tatgaaaacg actttatggg
    27841 gttctcatac gggttcagac ccgggcgaag ccagcacgat gcactggacg cactggccac
    27901 agggctggta cgcactaacg taaactgggt actggatgcc gacatcagac agttcttttg
    27961 aca
//
