LOCUS       NZ_CP069650            33290 bp    DNA     circular CON 18-JUN-2023
DEFINITION  Escherichia coli O7:H4 strain MIN14 plasmid pMUB-MIN14-MCR, complete
            sequence.
ACCESSION   NZ_CP069650
VERSION     NZ_CP069650.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN17831486
            Assembly: GCF_017570585.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli O7:H4
  ORGANISM  Escherichia coli O7:H4
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 33290)
  AUTHORS   Majewski,P.
  TITLE     Plasmid mediated mcr-1.1 colistin-resistance in clinical
            extraintestinal Escherichia coli strains isolated in Poland
  JOURNAL   Front Microbiol (2021) In press
REFERENCE   2  (bases 1 to 33290)
  AUTHORS   Majewski,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-FEB-2021) Department of Microbiological Diagnostics
            and Infectious Immunology, Medical University of Bialystok,
            Waszyngtona 15A, Bialystok 15-269, Poland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: Unicycler hybrid assembly v. v0.4.8-beta
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 06/18/2023 02:17:14
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,979
            CDSs (total)                      :: 4,859
            Genes (coding)                    :: 4,636
            CDSs (with protein)               :: 4,636
            Genes (RNA)                       :: 120
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 90
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 223
            CDSs (without protein)            :: 223
            Pseudo Genes (ambiguous residues) :: 0 of 223
            Pseudo Genes (frameshifted)       :: 61 of 223
            Pseudo Genes (incomplete)         :: 160 of 223
            Pseudo Genes (internal stop)      :: 47 of 223
            Pseudo Genes (multiple problems)  :: 45 of 223
            Pseudo Genes (short protein)      :: 4 of 223
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP069650.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..33290
                     /organism="Escherichia coli O7:H4"
                     /mol_type="genomic DNA"
                     /strain="MIN14"
                     /serotype="O7:H4"
                     /isolation_source="upper respiratory tract"
                     /host="Homo sapiens"
                     /db_xref="taxon:2810404"
                     /plasmid="pMUB-MIN14-MCR"
                     /geo_loc_name="Poland: Bialystok"
                     /lat_lon="53.12523570 N 23.15905989 E"
                     /collection_date="2016-07-21"
                     /genotype="ST-93"
     gene            complement(302..1024)
                     /locus_tag="JSU15_RS24260"
                     /old_locus_tag="JSU15_24260"
     CDS             complement(302..1024)
                     /locus_tag="JSU15_RS24260"
                     /old_locus_tag="JSU15_24260"
                     /inference="COORDINATES: protein motif:HMM:NF028536.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAP2 family protein"
                     /protein_id="WP_039003037.1"
                     /translation="MPYLSNKRLLAEMSIALVMAIVATLTLEHSQIDLMVADWFYLGMG
                     HWMVAKQAFLPDLLLYSGLKKLLMAMLIYLLVATICRAYHEKKGNAITAKWLVPVTKFR
                     VRELAYLVLTLILVPTVVASLKAYTHVVCPVHLTIFDGTLPYLPMLDSMRNTIPDKCFP
                     AAHASSGFALFAFAFAPSLRRRRGAIIIVVMALGWAMGCYKMIIGDHFLSHTVVSMMLA
                     WAMSAGLAWVFFKKGEQV"
                     /name="PAP2 family protein"
     gene            complement(1096..2721)
                     /locus_tag="JSU15_RS24265"
                     /old_locus_tag="JSU15_24265"
     CDS             complement(1096..2721)
                     /locus_tag="JSU15_RS24265"
                     /old_locus_tag="JSU15_24265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_049589868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine--lipid A transferase MCR-1.1"
                     /protein_id="WP_049589868.1"
                     /translation="MMQHTSVWYRRSVSPFVLVASVAVFLTATANLTFFDKISQTYPIA
                     DNLGFVLTIAVVLFGAMLLITTLLSSYRYVLKPVLILLLIMGAVTSYFTDTYGTVYDTT
                     MLQNALQTDQAETKDLLNAAFIMRIIGLGVLPSLLVAFVKVDYPTWGKGLMRRLGLIVA
                     SLALILLPVVAFSSHYASFFRVHKPLRSYVNPIMPIYSVGKLASIEYKKASAPKDTIYH
                     AKDAVQATKPDMRKPRLVVFVVGETARADHVSFNGYERDTFPQLAKIDGVTNFSNVTSC
                     GTSTAYSVPCMFSYLGADEYDVDTAKYQENVLDTLDRLGVSILWRDNNSDSKGVMDKLP
                     KAQFADYKSATNNAICNTNPYNECRDVGMLVGLDDFVAANNGKDMLIMLHQMGNHGPAY
                     FKRYDEKFAKFTPVCEGNELAKCEHQSLINAYDNALLATDDFIAQSIQWLQTHSNAYDV
                     SMLYVSDHGESLGENGVYLHGMPNAFAPKEQRSVPAFFWTDKQTGITPMATDTVLTHDA
                     ITPTLLKLFDVTADKVKDRTAFIR"
                     /name="phosphoethanolamine--lipid A transferase MCR-1.1"
     gene            complement(2815..3519)
                     /locus_tag="JSU15_RS24270"
                     /old_locus_tag="JSU15_24270"
     CDS             complement(2815..3519)
                     /locus_tag="JSU15_RS24270"
                     /old_locus_tag="JSU15_24270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000052343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2806 domain-containing protein"
                     /protein_id="WP_225236207.1"
                     /translation="MSLIDLSLSGLSEPGTKLIEKISDAIGVLYEPTRIRKKAKAEAEA
                     KRTELISRLELEGIEKRAVERFLKRETKRQENIENITMQAAQSLSESDNVSDIDEDWIE
                     AFFRECEDISDEQMQMLWGRILSEEAKSKGSFSRRTLKLLSTISKEEANLITYFGKFVW
                     QANKLTPILFTDENGDTEGITFDKLSVLDSLGVIQQGIGYSLQIINTLKCIFSMGLRND
                     CLIKFLKYFCIA"
                     /name="DUF2806 domain-containing protein"
     gene            complement(3680..3949)
                     /locus_tag="JSU15_RS24275"
                     /old_locus_tag="JSU15_24275"
     CDS             complement(3680..3949)
                     /locus_tag="JSU15_RS24275"
                     /old_locus_tag="JSU15_24275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001086090.1"
                     /translation="MAKLELPELEQNQEVNATKFVQDAGKRPTENKTKLASFRIPNELL
                     EFIDNESKRLHRPKTKIIKAALLAYQDLDENELINLWFRADRND"
                     /name="hypothetical protein"
     gene            complement(4024..4671)
                     /locus_tag="JSU15_RS24280"
                     /old_locus_tag="JSU15_24280"
     CDS             complement(4024..4671)
                     /locus_tag="JSU15_RS24280"
                     /old_locus_tag="JSU15_24280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001694199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division plane positioning ATPase MipZ"
                     /protein_id="WP_000587671.1"
                     /translation="MIIVIGGDKGGTGKSHLATNLTVCLSQQGKRTGLVETDLNGSTKK
                     WNKRREQAGLPPVALNEAYGDISAKITKMADVAEILIIDTAGYDSTEFRTALKVADIVI
                     VPIDPLAQVEADSLQTVTKIVRDAQKINPRLAAHVLLYKCQPNTFSEQQELRDSLNSHD
                     YWLKPMKSTVSFLRAFVRAMNQGMGVHELKSNVSGASQAKAQIELLLKELEL"
                     /name="division plane positioning ATPase MipZ"
     gene            complement(5331..5426)
                     /gene="dqlB"
                     /locus_tag="JSU15_RS25125"
     CDS             complement(5331..5426)
                     /gene="dqlB"
                     /locus_tag="JSU15_RS25125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinQ-like type I toxin DqlB"
                     /protein_id="WP_021534057.1"
                     /translation="MINMLIIVLRAVVAVANALIAVLELIRQFID"
                     /name="dqlB"
     gene            complement(6210..6912)
                     /locus_tag="JSU15_RS24285"
                     /old_locus_tag="JSU15_24285"
                     /pseudo=""
     CDS             complement(6210..6912)
                     /locus_tag="JSU15_RS24285"
                     /old_locus_tag="JSU15_24285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(6999..7463)
                     /locus_tag="JSU15_RS24290"
                     /old_locus_tag="JSU15_24290"
     CDS             complement(6999..7463)
                     /locus_tag="JSU15_RS24290"
                     /old_locus_tag="JSU15_24290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293133.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS family nucleoid-associated regulatory
                     protein"
                     /protein_id="WP_001293134.1"
                     /translation="MSELTKEDEYGIISRTMMNIRSLRVFAREIDFEQLLEMQEKLNVV
                     IEERREDAEREAAERQELEAKRQQAIEYIISLGLDPESLLAPVTADTVKTRRKAKGGVR
                     KAKYRFKDENGEIREWSGNGKRPLALQKLLDEGHFMEDFLIEKTKPEQAE"
                     /name="H-NS family nucleoid-associated regulatory protein"
     gene            complement(7481..7687)
                     /gene="hha"
                     /locus_tag="JSU15_RS24295"
                     /old_locus_tag="JSU15_24295"
     CDS             complement(7481..7687)
                     /gene="hha"
                     /locus_tag="JSU15_RS24295"
                     /old_locus_tag="JSU15_24295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="WP_000850859.1"
                     /translation="MKTKQEWLFQLRKCTSRDTLEKVIEINRYKLPLSESEAFYSAADH
                     RRAELVMNKLYDKVPSGVWKYVH"
                     /name="hha"
     gene            complement(7684..9837)
                     /locus_tag="JSU15_RS24300"
                     /old_locus_tag="JSU15_24300"
     CDS             complement(7684..9837)
                     /locus_tag="JSU15_RS24300"
                     /old_locus_tag="JSU15_24300"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247728.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="WP_001235745.1"
                     /translation="MRLFIAEKPAVANDIVKALGGNFTRHDGWFESDNAIVTNCFGHII
                     ESQPPENYNPEYKAWKVETLPLRLYPVKYQPVESAAKQVKTILELIRRGDVTEIVHAGD
                     PDDEGQLLVDEVLEYAGNTKPVKRVLINDNTLPAVKKALANLKDNRDFKGLYLKALARS
                     VADAVYGFSMTRAYTIPAKARGYQGVLSVGRVQTPVLGLIVNRTRANQNHKSSFYYTMT
                     GVFQRGADVIRANWKPGEFAPLTDRKLLDKAWADGTAASLAGKPATVEAAATDDKKTAA
                     PLPFNLVRLQQYMNKKFKMTAQKTLDITQQLREKYKAITYNRSDCSYLSDEQFSEAPQV
                     IDALKSVFPQSLDIDSARKSKAFNSAKVTAHTAIIPTASVPDVNALSTDERNVYLAIAQ
                     HYLVQFMPEKAYQEVSVAIQCGDESFYARARKTTDSGFEAFLGAETTDEGESEDNDDSA
                     FELLCKIRTGETLTTKEVIVNEKKTTPPPLFTEASLLAALVRVADFVTDPTIKKLLKDK
                     DKDKKDEHGGIGTPATRAAILETLKKRNYITLEKGKLIPTDTGYALIDALPGIAVNPDM
                     TALWSEKQAAIENGDLTVEQFINDLYGELTGMISDVDLGEMKIEPAAPAGQFQRLDSPC
                     PSCGKHIVIRPKGYFCTGCEFKIWSEFSGKKITQAQAEKLVKSGKTDLIKGFKKKSGGT
                     YDTVLVLEDKKTGKLGFPARAKK"
                     /name="type IA DNA topoisomerase"
     gene            complement(9842..10414)
                     /locus_tag="JSU15_RS24305"
                     /old_locus_tag="JSU15_24305"
     CDS             complement(9842..10414)
                     /locus_tag="JSU15_RS24305"
                     /old_locus_tag="JSU15_24305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001198960.1"
                     /translation="MQYALFDGFERKFLLDALEFGVLKDWKENPVKELPDIDESAHPFH
                     ICYGGYLLNPGVSDSDISRKIKDQAGFWLAAIDDTRMDCHSIAYYDIHTLPLISCGHQK
                     IVPFAALIKADECIISKIASYSGFAVTAFLRIKEWDIATNILNREGIFAFNGCERRFRV
                     VSKDNWQHTVSEERAIRCAKRLIQCKG"
                     /name="hypothetical protein"
     gene            complement(10418..>10612)
                     /locus_tag="JSU15_RS24310"
                     /old_locus_tag="JSU15_24310"
                     /pseudo=""
     CDS             complement(10418..>10612)
                     /locus_tag="JSU15_RS24310"
                     /old_locus_tag="JSU15_24310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517490.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /name="ATP-binding protein"
     gene            complement(10725..11027)
                     /locus_tag="JSU15_RS25020"
                     /pseudo=""
     CDS             complement(10725..11027)
                     /locus_tag="JSU15_RS25020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001350475.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            complement(11011..11433)
                     /locus_tag="JSU15_RS24315"
                     /old_locus_tag="JSU15_24315"
     CDS             complement(11011..11433)
                     /locus_tag="JSU15_RS24315"
                     /old_locus_tag="JSU15_24315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001353737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="WP_015059903.1"
                     /translation="MMKKLVFLLISILAGCSSPPEPTPVQFEKANEVINPSLPYVPDFH
                     GVIKSDVSGKGWVYEITSLSGVQARTPTFYYALAHADRIVVTTHDAGLWFRIRDLLKME
                     GATAVVEWRNEKSFLPEQVKIVFIKAQNEVKNDWKK"
                     /name="cag pathogenicity island Cag12 family protein"
     gene            complement(11442..13304)
                     /gene="taxB"
                     /locus_tag="JSU15_RS24320"
                     /old_locus_tag="JSU15_24320"
     CDS             complement(11442..13304)
                     /gene="taxB"
                     /locus_tag="JSU15_RS24320"
                     /old_locus_tag="JSU15_24320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome-coupling protein TaxB"
                     /protein_id="WP_170324155.1"
                     /translation="MKTFNKSQSVFIFAVMLVAAWFAGSFIFFVLYFSQIKNLKPLKAV
                     FRSIDAYRMDIFTDSLTLSVVTTDIRVLAFVALGAGFVVSLIIPVAALIKLNEKKENIF
                     GDARFATINDIRESNSFTLDGDEKDGIIVGIKDKKIIRYVGAAFSAMGAGTRAGKGAGI
                     VITNLMKYWWSVIILDPKRECFNITSLIRKVILGHEVYKFDPFSSVTHRFNPLYYVSMG
                     TSEGFNQLENLSLIIYPYKTDGADAGSYLNKTAGGVFKSYAVALWFMIKNDKAGLKTLD
                     IEPVFSMSKINQLFERAEPEHLLSFMNDIRSELRGKDKTLADIGVAGLKAFIEMEDKTK
                     AQLKSNFLNGLSPFANPNVANATDGNDFDLRQVRKKRMTIYFCISGDNARLAEKITNIF
                     FQLAIQVNLEKMPTDDPEIKHDCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQV
                     GSQLEEIYSYAGSKTLLASAPCKIVYSASDVKDARELSEAMGTRTVTIGSKSKSRSRGG
                     TSRSESESLIERPLVTTNELLTLKFSEEILAMKGENPIRCEKAFYYLNEYFFGDFVKVA
                     PELANIFPRKKGKLVMPPQKVFENEIVAKGYLVVKDVPDLDKAA"
                     /name="taxB"
     gene            complement(13291..14319)
                     /gene="virB11"
                     /locus_tag="JSU15_RS24325"
                     /old_locus_tag="JSU15_24325"
     CDS             complement(13291..14319)
                     /gene="virB11"
                     /locus_tag="JSU15_RS24325"
                     /old_locus_tag="JSU15_24325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401678.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_077249170.1"
                     /translation="MSGVIPVSISNKSLDFYKNQVFQSFLDIEGLTEIAVNRPGEIWTE
                     INGDWTFHNNDSVTFDFCKRFSHTLASFRGDEIGETKPLLSATLESGERVQVVFPPACE
                     RNTISITIRKPSTRQITHKEYVANGFYDYVQSGKKHRTYDDELLDLFRARNIAAFMELA
                     VAAGKTIVFAGATGSGKTTYMKSLIDFIPLNTRLITIEDAEEIKFFIHKNYVHLFYPSE
                     SGSDSGSIITAAKLIKSCLRMKPDRILLAEIKGGDAWDFVKVTGSGHSGSMTSIHAASA
                     KDAIIQMVTKCYQNRECQNLPFDVLRKIIMDSIDIVVHVGRDGVVRHMSDIYYKGAECE
                     NF"
                     /name="virB11"
     gene            complement(14321..15439)
                     /gene="virB10"
                     /locus_tag="JSU15_RS24330"
                     /old_locus_tag="JSU15_24330"
     CDS             complement(14321..15439)
                     /gene="virB10"
                     /locus_tag="JSU15_RS24330"
                     /old_locus_tag="JSU15_24330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB10/TraB/TrbI family type IV secretion system
                     protein"
                     /protein_id="WP_000131271.1"
                     /translation="MTDMKKTDDLVDDANQSKLESKPVHDIGDIRNKNNRMRSGFLFGL
                     MAVLVIGIFALKTYKNYFADDQQKASESTGDTSISQVSKIRTGLGQNFDPVENKAIINP
                     GATGSGNTVSDGHKEVPQEGFRKYLSIPVAGQGGSQTGASGSSRTSQTSEPQEERKESK
                     ENVPGKSGMKVTAINLDPDLYIEENRLIPCALTTRFVSDVAGRISCVFTEDVWSANHHT
                     KLLEQGTKAFGRYQTGTLNHGQGRMFVMWEQLRTPDNKRIDMVNTAAAGPLGEAGIDGW
                     IDSHFWERFGGSLMLSMVQDVAAAAADNAPGKDRNVDYTENSRQAMAEMAKVALENSIN
                     IPPTMYKNQGDIITIMVGEDIDFSDIYELKVK"
                     /name="virB10"
     gene            complement(15432..16340)
                     /gene="virB9"
                     /locus_tag="JSU15_RS24335"
                     /old_locus_tag="JSU15_24335"
     CDS             complement(15432..16340)
                     /gene="virB9"
                     /locus_tag="JSU15_RS24335"
                     /old_locus_tag="JSU15_24335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001299943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein VirB9"
                     /protein_id="WP_001329500.1"
                     /translation="MMKKLFIATCLLLPGLVYSAATPLPSGFDARMQTVSYNGANTTVI
                     RSKTGFLTSVVFDEGEAVISAKAGFPAGWEITTDDNVVYINPRPVVQEQEGDEGEKLKK
                     VFQPTEKEWDTNLFVRTTKRIYSLDLILLSEEKQAQPAYVVQFRYPSEIAKKNAEEVRL
                     AKEKQEKLRQKKLISESFEKADAPKNWNYFMRVNEKYDSRRIAPDFAYDNGIFTFLGFN
                     SGKVFPAPFAVRDGQEQTLAFNVETKGKYKIMVIHNVNDKFVLRYGNSVVGVVNKSFGK
                     VLTDQRNTSSPAVERVEVNND"
                     /name="virB9"
     gene            complement(16337..17023)
                     /locus_tag="JSU15_RS24340"
                     /old_locus_tag="JSU15_24340"
     CDS             complement(16337..17023)
                     /locus_tag="JSU15_RS24340"
                     /old_locus_tag="JSU15_24340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_001290765.1"
                     /translation="MSEKIEKKIETAKSFERQLYAENERSKKNAWRVAVAASLLSLCLG
                     AAICVLVPLKEKELAIVAVGEKTGRTELITQVKQEKILQSEALGRYFVNTYITLREGYN
                     YPSLQYDYETVQLYSSNTVKDDYLRLYNSDMAPDKIYHNNGSYVAVEVISNIISDATAP
                     DKLASVRFKKTTRNFTTGQVSVSYWTARVTYRFEPEKSVKSSSRELNPLGFTVTSYQTD
                     REVRGE"
                     /name="type IV secretion system protein"
     gene            complement(17538..18632)
                     /locus_tag="JSU15_RS24345"
                     /old_locus_tag="JSU15_24345"
     CDS             complement(17538..18632)
                     /locus_tag="JSU15_RS24345"
                     /old_locus_tag="JSU15_24345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001677777.1"
                     /GO_process="GO:0030255 - protein secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000046889.1"
                     /translation="MAQGFFVKYNSTVMDSVDKISSSYQTQFANDIMSLATVSVTLYVL
                     WKGYQILASKTQTPLQDLVWDLSKFAIIIMFITNADGYLTAATDALQGMKDGFSGGVSV
                     WQTLDNLWKSTQNLGAEIYSLDKSTYVKDQGVVGQFLIWTGSLILMAVSVVVFLTADVT
                     MKLLIITAPIFIFCLMFGFIRSMFNNWLQSLFSSILTVLFASLVIRIAMDFQGMILSHA
                     IRAAQTGNVNLVSTGAMGFMAGFLGALLVLIAKGFAVQLAGAGVEGAVQGAAMMGLGAA
                     GMATGKSLMLGGRAGLGFGLGMAGRTGMNSLSGKAGNLMGRGARTAAEWAGEKGYQALA
                     PTGALGMKARRLASLEKARARNAA"
                     /name="type IV secretion system protein"
     gene            complement(18644..19360)
                     /locus_tag="JSU15_RS24350"
                     /old_locus_tag="JSU15_24350"
     CDS             complement(18644..19360)
                     /locus_tag="JSU15_RS24350"
                     /old_locus_tag="JSU15_24350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000832283.1"
                     /translation="MKRVKTLMLISLLTASFYSSAGIPVAIDASPEWAVEAARWTERLK
                     QWSETAQHYQSQIQAYKDQLATATGIRNIAAFTNELSNLQSELTNIYKQGNSYISDFTS
                     NPEGALSSQAKNLFSKYGAFDMCNTGYERNDNLCKARIVSTAASIEQGNEINKQLSSAM
                     SQIQSLSSRIEASKDIKESQDLANALQAQSLKMQAIKMQYDVWNNKNKADHEMLVTQEQ
                     EAFIKQQKEAEPLTFD"
                     /name="type IV secretion system protein"
     gene            complement(19372..22119)
                     /locus_tag="JSU15_RS24355"
                     /old_locus_tag="JSU15_24355"
     CDS             complement(19372..22119)
                     /locus_tag="JSU15_RS24355"
                     /old_locus_tag="JSU15_24355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
                     /protein_id="WP_000105985.1"
                     /translation="MSTLYKAMTRPAMYVGVPVVPLTVVAGALFLAGVYISKLIWLAIP
                     VAVFVLRMITKQDDHIFNLYFLKLKMLGNSVCNRFFGARAFLSGQYEAVEIDEFVNAMK
                     LNERITTGKYIPYSSHVDKNIVKTKNGDYVATWQLMGINFESISAEMLETIDSQVATLV
                     RSFSGLPVSFYNHSCRASFYDAFTTKSGNKYADIISDCYYGSMKKNKFKGNTLYFTLIY
                     RPDGRVEKLEKRKKSIKEKKDDINIHVKRMNEMINTFSGALDKFTCKLLGMYEENGKVF
                     SSQLSFYNYLLTGKLQKIRVTDSPVYNVLGGVDVFFNHDTGQICRIDGNKFFRSIEIKD
                     FCSETASGVFDVLQYSDADYIITHSYTSMSKSEALSTIKRAEKQLKSTEDDAVTQLQEL
                     EKAKNDIVSGDISFGYYHFTLMVMADSIRELDESVSKITADFTDLGIIPALSTMSLPAA
                     YFAQLPAVFHLRPRLSPVSNVNFVELASFHNFYQGKRDKNCWTEAVAILKTPSKQAYYL
                     NLHNSVLFKDETGEKNLANTKVIGTAGSGKTMFLSYLACSLQKYNNPETFADSAKNKKL
                     TCVFLDKDRGAELCIRMLGGEYYTVKSGEPTGWNPFALEATKRNRIFVKQLMEILCTRN
                     GERLSTRERLLISESVDAVMDFPPGEMREYGITRMLEHLMQRDDRDEQENGIILRLSQW
                     ANGQAHGWVFDNAKDTFNIQHVNNFGIDGTEFLDDPMVCAPITFYLLYRITQLLDGRRL
                     VIFLDEFWKWLQDEAFSDFVYNKLKTIRKLNGLVIPATQSPDEILKNKISRAVVEVCST
                     SIYLANPDADYNDYVEGLKLTPEEFNIVKNLDPMSRQFLIKKSSLKKGDGKSFSALATL
                     DLSGLGGYLKILSASADNLEIFESIYHEGMEPDDWVPEYLERAI"
                     /name="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
     gene            complement(22138..22464)
                     /locus_tag="JSU15_RS24360"
                     /old_locus_tag="JSU15_24360"
     CDS             complement(22138..22464)
                     /locus_tag="JSU15_RS24360"
                     /old_locus_tag="JSU15_24360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_000008647.1"
                     /translation="MSFKKSVCNRISSSVTAVMQRKNKVVMAVAGATVASPAFADGFSK
                     AETLLEKVKTGLSGLSLVTVTIACLWVGYKVLFGGSTIRECSPIIIGAIVIASAAEVAS
                     MMVN"
                     /name="TrbC/VirB2 family protein"
     gene            complement(22525..23097)
                     /locus_tag="JSU15_RS24365"
                     /old_locus_tag="JSU15_24365"
     CDS             complement(22525..23097)
                     /locus_tag="JSU15_RS24365"
                     /old_locus_tag="JSU15_24365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001690148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_227537772.1"
                     /translation="MASLFPALLLCAASVHPDTINDIARVESGFNPYAVAEIIPERERG
                     SYGKSVISHMPKSKEEALTVIREIENRKRRYSVGLMQITSSNFSFYSTSAEKLLDSCEN
                     LSVFEKIIVDCYKRGRSLENALSCYYTGNFSNGKRKEKEFNNTSYVERIGYTGNEKNML
                     YQVQEATGENSEKIVHTMRQLSGPKPF"
                     /name="lytic transglycosylase domain-containing protein"
     gene            complement(23453..23668)
                     /locus_tag="JSU15_RS24370"
                     /old_locus_tag="JSU15_24370"
     CDS             complement(23453..23668)
                     /locus_tag="JSU15_RS24370"
                     /old_locus_tag="JSU15_24370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="WP_000760375.1"
                     /translation="MKKYLLFALPFFVVGCSEEVKSVDWWGQHLTEAKQKQAECEKSGS
                     DSQNCKNVKQALFIQSQKDAPVPTFD"
                     /name="EexN family lipoprotein"
     gene            complement(23665..23958)
                     /locus_tag="JSU15_RS24375"
                     /old_locus_tag="JSU15_24375"
     CDS             complement(23665..23958)
                     /locus_tag="JSU15_RS24375"
                     /old_locus_tag="JSU15_24375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134733.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]; GO:0016987 - sigma factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="WP_060598542.1"
                     /translation="MTEHDAICISGLHQIFSDEEHLSEQQKDIILMYAYGYTLNEIADF
                     KGLKPSTVRKYLDSVRAELGGVSLAGIRTLVLIRTNALLVSSLSRISERGNL"
                     /name="sigma factor-like helix-turn-helix DNA-binding
                     protein"
     gene            complement(24035..25264)
                     /gene="taxC"
                     /locus_tag="JSU15_RS24380"
                     /old_locus_tag="JSU15_24380"
     CDS             complement(24035..25264)
                     /gene="taxC"
                     /locus_tag="JSU15_RS24380"
                     /old_locus_tag="JSU15_24380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001329504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA relaxase/nickase TaxC"
                     /protein_id="WP_001329504.1"
                     /translation="MGVYVEQEYRIKRAKGTGRDPKSPKLSGRHIHASKSAFNHKVRHG
                     ADKKAYTWTPTKEVTFKITGSGKTAAGIKNGIDYITRNGELEAYCYDGKGSEQTGKGED
                     FNREFTSTLSKGNDYSRTYRGENIDHVKNMVFSPPPEAGVSREDALKATVEFLKETYPN
                     HAFVAVYHDDKEDHPHVHVNIKLRDEETGRRLRLTKSETRKFRNGFHRKLKGMGYDVTA
                     TWKKDPERKREIERLQAENPKRLRNVYKVVDFGETSYQNKAGEKRTPFLTYETLKGGKQ
                     VTIWGKDLKNHFESEKLQPGTLIKVKKLAPTLVRSPMFNDDGTVAGYRETHRNNWQIEN
                     IALERNRERQVHERETRQPEESDVKKQLSRKHEQGHNIGFALEHGFTKDSEEHKKLRIQ
                     QERNWKGLGF"
                     /name="taxC"
     gene            complement(25268..25771)
                     /gene="taxA"
                     /locus_tag="JSU15_RS24385"
                     /old_locus_tag="JSU15_24385"
     CDS             complement(25268..25771)
                     /gene="taxA"
                     /locus_tag="JSU15_RS24385"
                     /old_locus_tag="JSU15_24385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000781813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome-coupling protein TaxA"
                     /protein_id="WP_000781813.1"
                     /translation="MKMIAFRLSDDELKFAEHNAILSGFTSINAFAKHNVLNIETKPVN
                     IPVNNEPAKLVSVRLYPHEIELVKRNAALHGMSMSREIAIRVRQSLLKSEVCLYPDEVK
                     ELKKLSTAVDRVGRNIHFIIKGERFCTVNDPDFRKDVIEVIELCKQIDSKLETLTKSVV
                     NRFG"
                     /name="taxA"
     gene            complement(26132..26479)
                     /locus_tag="JSU15_RS24390"
                     /old_locus_tag="JSU15_24390"
     CDS             complement(26132..26479)
                     /locus_tag="JSU15_RS24390"
                     /old_locus_tag="JSU15_24390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="WP_000681613.1"
                     /translation="MKHLKYKGYLGTVEPDFENNVLYGKLAFIRDLVTYEASTLAELEQ
                     EFKTSVDLYLQSCVEDGKEPDTPFKGVFNVRLDPELHRRVAEMAMEEDLSLNAFVNKAL
                     EKEVSNHRAGA"
                     /name="type II toxin-antitoxin system HicB family
                     antitoxin"
     gene            complement(26476..26724)
                     /locus_tag="JSU15_RS24395"
                     /old_locus_tag="JSU15_24395"
     CDS             complement(26476..26724)
                     /locus_tag="JSU15_RS24395"
                     /old_locus_tag="JSU15_24395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005653200.1"
                     /GO_function="GO:0003729 - mRNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family toxin"
                     /protein_id="WP_000520549.1"
                     /translation="MGKTDKLLAKFLNSKKTFEWDELVVLFSSLGYVKKEMQGSRVRFF
                     NAEINHTILMHRPHPESYIKGGTLKAIKQNLKEAGLL"
                     /name="type II toxin-antitoxin system HicA family toxin"
     gene            complement(27029..27379)
                     /locus_tag="JSU15_RS24400"
                     /old_locus_tag="JSU15_24400"
     CDS             complement(27029..27379)
                     /locus_tag="JSU15_RS24400"
                     /old_locus_tag="JSU15_24400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000854261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000854259.1"
                     /translation="MKTLKQAAMQFASDLRNNRCFKAAYNDALLELDREDLNAIVQCTF
                     LFEPKRTLAELDKLIKKIEVEEDYEFCVSLDKGKGLHEVRTFKSEREALDAYRILTLYG
                     YTVTIEKKEGND"
                     /name="hypothetical protein"
     gene            complement(27470..27769)
                     /locus_tag="JSU15_RS24405"
                     /old_locus_tag="JSU15_24405"
     CDS             complement(27470..27769)
                     /locus_tag="JSU15_RS24405"
                     /old_locus_tag="JSU15_24405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000650309.1"
                     /translation="MKCSSVFTSTTNHVFTFERVTLCTIILMHKDTGQQYVVIFTDNNK
                     IRDYKAGIVPQFGELKQSDVDLVLFYRDEYEKYFDSLKDGDECLSFKDFIECLC"
                     /name="hypothetical protein"
     gene            complement(28223..28450)
                     /locus_tag="JSU15_RS24410"
                     /old_locus_tag="JSU15_24410"
     CDS             complement(28223..28450)
                     /locus_tag="JSU15_RS24410"
                     /old_locus_tag="JSU15_24410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000801440.1"
                     /translation="MKPDNTPENVKKLRLKAGLTQKECSHIYGVGLRTWQKKEEVNTQN
                     SQSLSLVEFEFLLLLAGEHPEYVLCKRESK"
                     /name="hypothetical protein"
     gene            complement(28437..28688)
                     /locus_tag="JSU15_RS24415"
                     /old_locus_tag="JSU15_24415"
     CDS             complement(28437..28688)
                     /locus_tag="JSU15_RS24415"
                     /old_locus_tag="JSU15_24415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001565860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001230707.1"
                     /translation="MRKNKGDVTYFLEKEGDNYRLTKRIKARTNVKIGNKTTKITLYDA
                     VLNENELQHIDFTCAGLREDDETPVKNLIKEFMLNETR"
                     /name="hypothetical protein"
     gene            complement(28685..29227)
                     /locus_tag="JSU15_RS24420"
                     /old_locus_tag="JSU15_24420"
     CDS             complement(28685..29227)
                     /locus_tag="JSU15_RS24420"
                     /old_locus_tag="JSU15_24420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001083906.1"
                     /translation="MNSFFEQYHPVFEVVCRILGNGWRVNKLDDCSSRIKLTSPQFKNY
                     SVHIRMEKDRFSVVGSVDSRSWRSPHHVCTLSRKRNPVDIAADIERKILVNASQEVLQA
                     IEYEKHQVEKKDEILILKGMLSQLVQLESWYGALTGFKAENGLNGKVTEQGDSYDLQIR
                     GLSIDQLVKITGYLKQL"
                     /name="hypothetical protein"
     gene            complement(29332..29847)
                     /locus_tag="JSU15_RS24425"
                     /old_locus_tag="JSU15_24425"
     CDS             complement(29332..29847)
                     /locus_tag="JSU15_RS24425"
                     /old_locus_tag="JSU15_24425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025391.1"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="WP_001025395.1"
                     /translation="MNIQEALNVFGLSGELTEKDIKAAYRKAALKYHPDRNPLGAELMK
                     AVNAAFDVLMANIDKINQFQSTDEHARYNYGDDLEKVLNVLSGLSGLVFEVIGNWVWIS
                     GETITHKETLKEIGCKWAAKKKQWFYRPDEHKSYWNREEHTIEEIRAKYGTTGQRRATG
                     WQRVETRA"
                     /name="J domain-containing protein"
     gene            31259..31960
                     /locus_tag="JSU15_RS24430"
                     /old_locus_tag="JSU15_24430"
     CDS             31259..31960
                     /locus_tag="JSU15_RS24430"
                     /old_locus_tag="JSU15_24430"
                     /inference="COORDINATES: protein motif:HMM:NF013235.2"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_251361261.1"
                     /translation="MTTNKTSLSRLTKVRHRNELNSTLSTLPMAAKKVLFLAMCQINSK
                     NEFDDDHIFYVTVADYIKWVQVKPDAAYLALRDGSNILDTTLLKLKHDEILELSSDLGF
                     KFTKSNVPDSMNLSLTVFSTYYRNEGRVGIKFTKEAKRFLCKLIGEEKRYTTQVLLSVV
                     RLTSVNAASLYQLIRKIYSNNSRANSFEMTIDELKDELNLYTIGAGVKDYKYPDYPAFK
                     RDVLNKSVKKS"
                     /name="replication initiation protein"
     gene            32135..32539
                     /locus_tag="JSU15_RS24435"
                     /old_locus_tag="JSU15_24435"
     CDS             32135..32539
                     /locus_tag="JSU15_RS24435"
                     /old_locus_tag="JSU15_24435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012421203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_208232115.1"
                     /translation="MKDNIVDFQRIRDSMNDHSTDVANDAVYSDKKKISRFFYLLTPVR
                     YLLAASLYLVVVIPLGILAGFRFLLQFLGGIAVMGLTIARYMGADVSSYVVLAAWIALT
                     VCGCAEQIFEWWIESRFAFRLFGIGRTPEE"
                     /name="hypothetical protein"
     gene            32674..33201
                     /locus_tag="JSU15_RS24440"
                     /old_locus_tag="JSU15_24440"
     CDS             32674..33201
                     /locus_tag="JSU15_RS24440"
                     /old_locus_tag="JSU15_24440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001473365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2726 domain-containing protein"
                     /protein_id="WP_000577043.1"
                     /translation="MIFNRNKKRDEQHNSAVVLPSAENVFSDFIKNNPALTTNAFTAIG
                     EVDCFTKVPLLSNNESEFLGILSRNIIPDYSVFPKIRLIEFVRPHGSEEAVKDLIREVQ
                     NITCDFVLKSYDETVLAVIQFGETATVRQQKKKLIIQRVCAMTGISFFEFKNTVDMMGS
                     EDFCQFLRDDEE"
                     /name="DUF2726 domain-containing protein"
     ARG             complement(1100..2721)
                     /name="mcr-1.1"
                     /gene="mcr-1.1"
                     /gene_name="phosphoethanolamine--lipid A transferase
                     MCR-1.1"
                     /tool="amrfinderplus"
                     /drug_class="COLISTIN"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          31254..32122
                     /name="IncX4"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.428"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(24039..25264)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.511"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(11446..13304)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="98.71"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(15436..16340)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.669"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(16341..17023)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.4399999999999998e-137"
     Typing          complement(17566..18632)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.719"
                     /coverage="99.0"
                     /evalue="2.69e-172"
ORIGIN
        1 ggcagttttt gcggtcgctt ttaattatgg ttagtggaac tcagacaggt aactcgacct
       61 ctttacatat taataattga tagttttacc tggcttcctt caacatttat tttgttgagg
      121 aatttattta aatacgcaat atctggagtg gaaccgcata ttttcatcaa ttcttgaccg
      181 ataggcgtaa gtaaagccgt tcctattggt agtttccagg ttgatgaatc atcgctttga
      241 aactcaactg aaaaaaccgt tccgtaataa ccgatacgac cgtttttact tttaaaggcg
      301 attaaacttg ttcacccttc ttaaaaaaca cccacgcaag ccctgccgac atcgcccacg
      361 caagcatcat cgacaccacc gtatggctca aaaaatgatc gccaataatc atcttatagc
      421 agcccatcgc ccagcccaat gccatcacca cgatgatgat cgcaccacga cggcggcgca
      481 aacttggcgc aaacgcaaag gcaaacagcg caaatccgct actggcatgc gccgcaggaa
      541 agcacttatc aggaatggtg ttacgcatac tatcaagcat cggcaaatac ggcagcgtac
      601 catcaaaaat cgtcaaatgc acagggcaga ccacatgagt atatgccttc aatgacgcga
      661 caactgtcgg cactaggatc aaagtcagca ccagatacgc aagctcacgc acgcgaaatt
      721 ttgtcactgg gacaagccac ttggcagtga tagcattgcc ctttttctca tgataagcac
      781 ggcaaatggt cgcaaccagc aagtagatca gcatcgccat cagcagcttt tttagtccag
      841 aatacagtag caaatctggc aaaaaagctt gcttggcaac catccaatgc cccataccca
      901 gataaaacca atcagcgacc atcagatcaa tctgactgtg ctcaagggtc agcgtggcaa
      961 cgatcgccat gacaagagcg atactcatct cagcaagtag gcgtttattt gataaatacg
     1021 gcataacaaa ccccacccca ccgcccataa tacgaatgga gtgtgcggtg ggtttggaaa
     1081 aaatacaggg agaaatcagc ggatgaatgc ggtgcggtct ttgactttgt ccgcggtgac
     1141 atcaaacagc tttaataatg tcggcgtgat cgcgtcatgg gtcaggacgg tatcggttgc
     1201 cattggcgtg atgccagttt gcttatccgt ccagaaaaat gcaggcacac tgcgctgttc
     1261 ttttggtgca aaggcatttg gcataccatg tagatagaca ccgttctcac ccagactttc
     1321 gccatgatcg ctgacataca gcattgagac atcataggca ttgctgtgcg tctgcagcca
     1381 ctggatactt tgagcgatga aatcatcggt ggcaagcaag gcattgtcat aagcattgat
     1441 caaggactga tgttcgcact tggcaagctc attaccttca cacactggcg tgaatttggc
     1501 aaacttttca tcatatcgct taaaatacgc aggcccgtga ttgcccattt ggtgcagcat
     1561 gatcagcata tctttgccgt tattggcagc gacaaagtca tctaagccaa cgagcatacc
     1621 gacatcgcgg cattcgttat aaggattggt gttgcagatg gcgttgttgg tcgcggattt
     1681 ataatcggca aattgcgctt ttggcagctt atccatcacg ccttttgagt ccgaattatt
     1741 atcacgccac aagatactta cgcccaagcg atccagcgta tccagcacat tttcttggta
     1801 tttggcggta tcgacatcat actcatccgc gcccagatag ctgaacatac acggcacaga
     1861 atacgccgtc gatgtgccgc acgatgtgac attgctaaaa ttggtcacgc catcgatctt
     1921 ggcaagctgt gggaaagtat cgcgctcata gccattgaag ctgacatgat cggcgcgtgc
     1981 cgtctcaccg acgacgaaca ccactaggcg tggcttacgc atatcaggct tggttgcttg
     2041 taccgcgtct ttggcgtgat aaatggtatc ttttggcgca ctggcttttt tatactcaat
     2101 actggcaagc ttacccaccg agtagattgg catgatcgga ttgacatagc tacgcagcgg
     2161 cttatgcacg cgaaagaaac tggcataatg actgctgaac gccaccacag gcagtaaaat
     2221 cagcgcaaga cttgccacga tcaagcccaa tcggcgcatc aaacccttgc cccaagtcgg
     2281 ataatccacc ttaacaaaag ccacaagcaa acttggtagc acacccaaac caatgatacg
     2341 catgataaac gctgcgttta atagatcctt ggtctcggct tggtcggtct gtagggcatt
     2401 ttggagcatg gtcgtatcat agaccgtgcc ataagtgtca gtaaaataac tggtcaccgc
     2461 gcccatgatt aatagcaaaa tcaacacagg ctttagcaca tagcgatacg atgataacag
     2521 cgtggtgatc agtagcatcg cgccaaagag cacgacagcg atcgtcagca caaagccgag
     2581 attgtccgcg atgggatagg tttggctgat tttatcaaaa aaggtaagat tggcggtcgc
     2641 ggtcaagaaa acggcaacac tcgccacaag aacaaacgga ctgaccgagc gtcggtacca
     2701 cacagaagta tgctgcatca tgagaaacta ctcaaaaaat aaacggcggg ataattgcgg
     2761 caattatact gcaatttttt aagaaatcca gtacaattta tctgatataa aaaattatgc
     2821 gatacagaaa tatttcagaa attttattag gcaatcattg cgcaatccca tactgaatat
     2881 acacttgaga gtatttataa tttgtaaact ataaccaatg ccttgttgaa taacgcctaa
     2941 ggagtctaaa accgaaagtt tatcgaaagt tataccttca gtatctccat tctcatcggt
     3001 aaataaaatt ggagtgagtt tgtttgcctg ccaaacaaac tttccaaaat aagtaataag
     3061 gttcgcttct tctttgctta tagtggataa tagttttaag gttctacgac taaacgaacc
     3121 ttttgacttt gcttcttcgg ataaaattct tccccaaagc atttgcattt gttcgtcact
     3181 aatatcctca cactccctga agaaagcctc tatccaatct tcgtcaatat cagaaacatt
     3241 atcactctca gatagacttt gtgctgcttg cattgttata ttttcaatgt tttcctgtcg
     3301 tttcgtttca cgtttgagaa aacgctcaac tgcccgtttt tctattccct caagctctaa
     3361 cctagaaatt agctctgtgc gtttagcttc agcttcagcc ttcgcttttt tcctgattct
     3421 tgtaggttca taaagcacac caatagcatc acttattttt tcaataagtt ttgttcctgg
     3481 ttctgataat cctgataaac ttaaatcgat aaggctcatc tagtgctcct aaatacccgt
     3541 gcaacaactg tacaagggta ttttattgca agagtaacta aaaatgaatc acaactacat
     3601 ttaaaagtga tgaagttagt acattcagat aagtatctaa aagaaaatga taaagagttt
     3661 attgggccac ttgctatgat taatcatttc tgtcagctct gaaccacaaa ttaatgagtt
     3721 cgttttcgtc cagatcctga taagccagta atgctgcttt gattattttt gtcttgggac
     3781 gatgcagtct ttttgattcg ttatcaatga attcaagcaa ttcattcggt atgcggaatg
     3841 aagccagttt tgttttgttc tctgtggggc gttttcctgc gtcctgaaca aattttgtgg
     3901 cgttcacttc ctggttttgt tctagttctg gtagttccag ctttgccatg atgtaccttc
     3961 taatctgatt gtttcacact aatgtatatc atgatgatgt acattagtgt atgtcactat
     4021 gatttacagt tccagttctt tcagcaagag ttcgatttgt gcttttgcct ggctggcacc
     4081 gctaacatta ctttttaact cgtgaacccc cattccctga ttcattgctc ttacaaaggc
     4141 ccggagaaaa gaaaccgtgc ttttcattgg tttaagccag taatcatggc tgttgagaga
     4201 gtctcttaat tcttgttgtt cactgaacgt atttggctgg catttataca ggagcacatg
     4261 tgcagccagc ctgggattta ttttttgcgc atccctgaca atttttgtca cagtctgaag
     4321 actgtctgct tccacctggg caagcgggtc gatcgggaca atcacaatgt ctgcaacttt
     4381 tagtgcagtt ctgaactccg tgctgtcata tccggcagta tctataatga ggatttctgc
     4441 tacatctgcc atttttgtta ttttggcact gatgtcgcca taggcttcat ttaatgcgac
     4501 gggcggtaat ccggcctgtt ctctgcgttt attccatttt ttggtcgagc cattcaggtc
     4561 tgtttcaaca agccccgttc tctttccctg ttgtgagagg caaacagtta agttggttgc
     4621 cagatgtgat ttacctgtac cgcctttatc accaccgatt acgataatca tagtacccct
     4681 tgtatgtcac agtgatttac tcatgtgtat ttctatgtga tgtacgcatg cgtatgtcac
     4741 atggacatac tatagtgtat gtcacaatga attacaatga tgtacatcat gaagaaatac
     4801 attattgtat gtcagtgtga tgtacccgtt ggttggtcac ttgaaagcaa aagtgacagc
     4861 gttactttcg gtatcctccc ttgctgcgaa accttgtggc aatacagcaa tgagtatgtt
     4921 tagttacaac attcaaaatt aagcgattag attccgcccg tacgggcggg cgcgccactt
     4981 tctgtagtgg gaggggcagg aggttatgtt tgctggatga gcggaggatg gaatgagcta
     5041 ttagaatgtt gtaactaaag ggtatcccaa ttaaaggcca cttacgcggc ctttgtctgt
     5101 cggttcttcg gtctggtgac ataccacgat aaacatccca cagcaacact cataagcatt
     5161 ccggataagc gatcatcgat gccaggaaac aggcaaccga caaacatcgc aacagggaaa
     5221 ggaagaagta aacagcgccc caaaatgctc ataaaatcca taaatcctcc ttttttgtta
     5281 aagggcagga agcggttcac ttcctgccct tagttacgtt tccgttgtca tcaatcgatg
     5341 aattggcgga tcagttccag aactgcaatc agcgcgtttg caacggcgac cacagctctg
     5401 agaacgatga ttaacatatt aatcatccgt ttctccagta aaactggagg aaatcaccgt
     5461 tgcttgctca tacactgcct gtcacaacgg ctctctcgca ttgttaggtg tagagtgacc
     5521 tcctcctgcc agagcaccga atacagcacc acctgtttat ccagcccggg actttaaaat
     5581 cgttcatacc cgcagatacg ggaacagcag gattgcaagc caactacatg actaactgac
     5641 tgattatacg ctacacaaaa cacccgttac accactaaat gtggttcctt aaccacattt
     5701 agttgcttta cagcaccata gtgaataaaa tgtaaacgtt aggtgtagag taaccttctc
     5761 cggtcagagc caccaactca agactggaaa acgcaaaaaa gcccgattac cagtcgggtt
     5821 tttttgtgcc tgtcgttcgg ctgtagttcc gttttttctc cttcatttga gggatttttc
     5881 tttcattttt tttgttgctt ccaatactgc ctgtcgcgtt ggccaacagc ttgacgcgtt
     5941 accggcattt tcattactca atatttttca gtgaattaaa atgcaacagc gacagaaaag
     6001 gacattcagc tttttagatg aatgctatag caacggtgtg ctacgtaaaa tctgcgaaaa
     6061 aagcaggggt agggtaggtt atttttcacg tagcaacgcc atctggcact gtacataggt
     6121 atgtcacaca gacataccta tgtgtatgtc tgtgtgaggc actgttgcaa agttagcgat
     6181 gaggcagcct tttgtcttat tcaaaggcct tacatttcaa aaactctgct taccaggcgc
     6241 atttcgccca ggggatcacc ataataaaat gctgaggcct ggcctttgcg tagtgcacgc
     6301 atcacctcaa tacctttgat ggtggcgtaa gccgtcttca tggatttaaa tcccagcgtg
     6361 gcgccgatta tccgtttcag tttgccatga tcgcattcaa tcacgttgtt ccggtactta
     6421 atctgtcggt gttcaacgtc agacgggcac cggccttcgc gtttgagcag agcaagcgcg
     6481 cgaccatagg cgggcgcttt atccgtgttg atgaatcgcg gatctgccac ttcttcacgt
     6541 tgttgaggat tttacccaga aaccggtatg cagctttgct gttacgacgg gaggagagat
     6601 aaaatcgaca gtgcggcccc ggctgtcgac ggcccggtac agatacgccc agcggccatt
     6661 gaccttcacg taggtttcat ccatgtgcca cgggcaaaga tcggaagggt tacgccagta
     6721 ccagcgcagc cgtttttcca tttcaggcgc ataacgctga acccagcggt aaatcgtgga
     6781 gtgatcgaca ttcactccgc gttcagccag catctcctgc agctcacggt aactgatgcc
     6841 gtatttgcag taccagcgta cggcccacag aatgatgtca cgctgaaaat gccggccttt
     6901 gaatgggttc atgtgcagct ccatcagcaa aaggggatga taagtttatc accaccgact
     6961 atttgcaaca gtgccctgtg tgatgtatac ctggcgggtt attctgcctg ttccggctta
     7021 gttttctcaa tgaggaaatc ttccatgaaa tgcccctcat caagcagctt ctgtaaagca
     7081 agcggacgct tgccattacc agaccattct ctgatctcgc cattttcatc cttaaagcgg
     7141 tatttagcct ttcttactcc gcctttggct ttccgcctgg tttttactgt atctgctgtt
     7201 acaggagcaa ggagtgattc gggatcaaga cctaaagata tgatgtattc aatggcctgc
     7261 tgacgtttgg cttcaagttc ctggcgttca gccgcttcac gttcagcatc ttcacgacgt
     7321 tcttcaataa caacgttgag cttttcctgc atttcgagca actgctcaaa atcaatctca
     7381 cgggcaaaaa cacgcaatga acgaatattc atcatagtac ggctgataat gccgtattca
     7441 tcttctttag tcagttcgct catataatta atcctcttat ttagtgtacg tacttccaga
     7501 cgccggaagg caccttatca taaagtttat tcatcaccag ttctgctcgg cgatgatctg
     7561 cggcagaata aaatgcctct gattctgata aaggcagttt gtaacggtta atctcaataa
     7621 ctttttcaag agtatctctt gatgtacatt ttcttaactg aaaaagccat tcctgctttg
     7681 ttttcacttc ttagcccttg ccggaaaacc cagcttccct gttttcttat cctcaaggac
     7741 aagaactgta tcatacgttc caccactttt ctttttaaat cccttaatca aatcggtttt
     7801 ccctgattta accagttttt cggcctgtgc ctgggtgatt ttcttaccag aaaactcact
     7861 ccagatttta aattcacatc cggtacagaa ataacctttc ggcctgataa caatatgttt
     7921 accacaggaa gggcagggag agtccaggcg ttgaaactgc cctgctggcg cagcgggttc
     7981 aatcttcatc tcgcccaggt caacatcaga aatcatgcct gtcagttcac cgtacagatc
     8041 attaataaac tgttcaaccg tcaggtcgcc attttctatg gcagcctgct tttcagacca
     8101 taatgctgtc atatcaggat taaccgctat accaggcagg gcatcaataa gcgcatatcc
     8161 ggtatcagta ggaataagtt tccctttttc cagcgtgata tagtttcttt tcttcagcgt
     8221 ttccagaatg gctgcgcggg tagctggcgt accaatgcca ccatgttcat cttttttgtc
     8281 tttatcctta tccttcaaca attttttaat tgttggatca gtgacaaaat ccgcgacacg
     8341 aacaagcgca gcaagcaagg aggcttcggt gaataacggc ggcggtgttg ttttcttctc
     8401 attaacaata acttcttttg tcgtcagtgt ttctcctgtg cgaattttac agagcagttc
     8461 aaaagcggaa tcatcattat cttctgattc accttcgtct gtggtttccg cgccaagaaa
     8521 cgcctcaaat ccgctgtcag ttgtttttct ggcacgggca tagaacgact catcaccaca
     8581 ctgaatggca accgatactt cctggtatgc tttttcaggc atgaactgaa caagatagtg
     8641 ttgtgcgatc gccaggtaaa cattgcgctc gtcggtgctg agtgcgttaa catcaggcac
     8701 actggcggtc gggattatcg cagtatgcgc agtcaccttt gcactgttaa acgctttgct
     8761 tttacgtgca gaatcaatat ccagcgactg aggaaagact gatttcaggg catcgataac
     8821 ctgcggcgct tcgctgaatt gttcatctga aagatatgag cagtcagagc ggttatacgt
     8881 aattgcttta tatttttcgc gtagttgttg cgtaatatcc agcgtttttt gtgccgtcat
     8941 tttaaacttc ttgttcatgt attgctggag tctgaccaga ttaaacggca acggcgcagc
     9001 cgttttttta tcatcagttg ctgctgcttc aactgtagcc ggttttcctg caagggatgc
     9061 agccgttccg tctgcccacg ctttatcaag taatttacgg tctgtcagcg gagcaaattc
     9121 ccctggcttc cagttcgccc tgataacatc agcaccacgc tgaaagactc cggtcatggt
     9181 gtagtaaaaa ctggatttat ggttctggtt agcacgggta cgattcacaa tcaggccaag
     9241 aacgggagtc tggacgcgcc cgacagacag aacgccctga tatcctctgg cttttgccgg
     9301 aatggtgtac gcacgtgtca tagagaagcc atagacggca tcggcaactg accgcgccaa
     9361 cgccttaagg taaagtcctt tgaaatcacg attgtcttta agatttgcca gtgccttttt
     9421 cactgccgga agcgtgttgt cgttaatcag aacgcgcttt acgggttttg tgttgcctgc
     9481 atattccagg acttcatcaa ccagtagctg tccctcatca tcaggatcgc cagcgtgaac
     9541 aatttcagtc acgtctccac gtctgataag ttcgagaatc gttttaacct gttttgctgc
     9601 actttcaaca ggctgatact tcacgggata aagacgtaaa ggaagcgttt caaccttcca
     9661 ggctttgtat tcaggattat agttttccgg cggttgtgat tcgataatat gaccaaaaca
     9721 gttagtcaca atggcgttat cactttcaaa ccagccatca tggcgggtaa aattgccacc
     9781 aagtgcctta acaatatcat ttgctactgc gggtttttct gcgataaaaa gtctcatttt
     9841 gttatccttt acattgaatt aatcttttgg cacaacggat agcgcgttct tccgatactg
     9901 tatgttgcca gttatcttta cttactactc tgaatctgcg ctcacagcca ttaaaggcaa
     9961 aaattccctc acggttaagt atattagttg caatatccca ctctttaatt ctcaaaaagg
    10021 ctgttacagc aaaaccagaa tacgaagcaa tttttgaaat gatgcattca tcagctttta
    10081 ttaacgcggc aaaaggaact atcttttgat gaccacacga aatcagaggg agtgtgtgaa
    10141 tatcataata agctattgaa tgacaatcca tgcgggtatc atcaatagct gccagccaga
    10201 atcctgcctg gtcttttatt tttctgctaa tatctgaatc tgaaacacca gggtttaata
    10261 aatatccacc ataacagata tggaaggggt gagcagattc atcaatatca ggaagttctt
    10321 ttaccggatt ttctttccag tccttcagaa caccgaattc aagagcatcc agcaaaaact
    10381 ttcgttcaaa tccatcaaac aatgcatatt gcatgtgtta atcctccagg taacttaaat
    10441 agtcaggttg tgccccgttc tttttataaa gttcttccct ttcctctata tcttcatctg
    10501 cttcctgaac gctcagatcg agggttcctt tcaaaaaggc acgagcattt tttattacat
    10561 ccacttatgc actaccagca gataagcaca ataaaatagc tataatagat ttggttactt
    10621 tcatttctaa cctcagtgat tgtaactaat catcacattt cgttggcgcg aaatgtgata
    10681 cttgcagtac cctgataccc gttggcgcgg ttatcaggtt ttaattaacc tctgacacga
    10741 ccaaacttac tcatgatttt tgatatagca gcaggatcag ccgttgaaca ctgattcaga
    10801 aatgctttac gggcatcaaa agttttactc cagcgaatgc ttcctttttc tttttcagaa
    10861 tattaaaaat ccttttcagc acttctgcat tcactccctc caccttgccc gactgctttt
    10921 ccatataagc aaagtaccga agcgcaaggg tcagatgcat tagcatttgt tgatattaat
    10981 cctaacgcca gcaaggctgg taaaaccact ctattttttc cagtcatttt tcacctcatt
    11041 ttgtgcttta atgaaaacta tttttacctg ttcaggtaaa aaacttttct cgtttcgcca
    11101 ttccacgact gctgttgccc cttccatctt caacagatct ctgattcgaa accacagccc
    11161 agcatcatgt gttgtcacta caatcctgtc cgcatgagcc agagcgtaat aaaacgtcgg
    11221 cgttctggcc tgtactccgg ataaggaagt gatctcataa acccatcctt taccgctaac
    11281 gtctgacttt atgacaccgt gaaaatcggg gacatatggc aatgagggat tgatcacttc
    11341 atttgccttt tcaaactgca cgggtgttgg ctctggcggt gatgaacaac cagcaagaat
    11401 ggaaatcaat aaaaacacta acttcttcat catgttctcc tttatgccgc tttatcgaga
    11461 tcaggaacat cttttactac cagataccct tttgcgacga tttcattttc aaatactttc
    11521 tgtggaggca taaccagctt tcctttcttc ctggggaaaa tgtttgcaag ttccggagca
    11581 accttcacaa agtcaccaaa gaaatactca ttgagatagt agaatgcctt ttcacaacga
    11641 atcgggtttt ctcccttcat tgccaggatt tcttcactaa atttcagtgt aagtagttca
    11701 tttgttgtta ccagtggacg ctcaataagg ctttctgatt cagatctcga tgttcctcca
    11761 cgactacgac ttttgctttt cgaaccgata gttactgttc gtgtccccat cgcttctgat
    11821 aactcccgcg catctttaac atcagaagcg gaataaacaa ttttgcaggg tgcacttgcc
    11881 agtaatgttt tactgcctgc ataactgtag atttcctcaa gctgagagcc gacctggtaa
    11941 acaatcaaca atttcagctt gtaaccagca atgagaccag atttactctt gatgtaatct
    12001 acagcaccaa ttgacgggaa ttcatccagt agaaaaaggc agtcatgctt tatttccgga
    12061 tcatccgttg gcatcttttc aagattcacc tgtatagcaa gctgaaagaa aatatttgtt
    12121 attttttcag ccaacctggc attatcacca gaaatacaga aataaattgt catccgcttt
    12181 ttccgcacct gccgcaaatc aaaatcattt ccatcagtag catttgccac attggggtta
    12241 gcaaacggtg ataatccatt aagaaagttg cttttgagtt gtgcttttgt tttatcctcc
    12301 atctcaatga atgccttaag gccagcgaca ccaatatcag caagcgtttt gtctttcccc
    12361 cttaattctg aacgaatatc attcatgaat gaaagaagat gttcgggttc tgcacgctca
    12421 aaaagctgat taattttaga cattgagaag acaggctcaa tatcaagcgt ttttagtcca
    12481 gccttatcat tcttaatcat aaaccataaa gcgacagcat aagatttaaa aacaccaccc
    12541 gccgtcttat taagatagct accagcatcc gcaccatctg tcttataggg gtaaataatc
    12601 aacgaaagat tttcaagctg attaaaacct tcactcgttc ccatgctgac ataatacaaa
    12661 gggttaaagc ggtgcgttac cgaactaaag ggatcaaatt tataaacctc atgacctaaa
    12721 atcaccttcc tgataagact ggtgatatta aaacactccc tttttggatc gagaataata
    12781 acactccacc agtacttcat aagattagtg atgactatac cagcaccttt accagccctt
    12841 gttccggctc ccatagcact gaatgctgct cccacatagc gtatgatttt cttgtctttt
    12901 ataccaacga taatcccgtc tttttcgtca ccgtcaagcg tgaaactgtt agactcacga
    12961 atatcattaa ttgttgcaaa tcgcgcatca ccgaaaatat tttctttctt ctcgttcagt
    13021 tttatcaacg ccgcaacagg gatgataaga gacacgacaa atcctgctcc aagtgcaaca
    13081 aaggctaaaa ctctgatatc cgtagtcaca acagataaag taaggctgtc tgtaaaaata
    13141 tccatcctgt acgcatcaat ggatctgaac acagccttca atggtttcag attctttatc
    13201 tggctgaagt aaagcacaaa gaaaataaat gaacctgcaa accatgccgc aacaagcata
    13261 acagcgaata taaaaacaga ttgcgactta ttaaaagttt tcacattcag cccctttgta
    13321 atagatgtcg ctcatatgcc tgacaacacc atccctgcct acatgaacaa caatatcaat
    13381 actgtccata atgattttac gaagaacatc aaaaggaaga ttctgacatt ctctgttctg
    13441 ataacatttt gtcaccatct gaatgatggc atcttttgcc gaggccgcgt gaatggacgt
    13501 catgcttcca ctgtgaccag aaccagtaac tttcacaaaa tcccaggcat cgccaccttt
    13561 aatttccgcc agtaaaattc tgtcaggttt catcctcaaa caggatttga ttaatttcgc
    13621 tgctgttatg atagagccgg aatcactgcc ggattccgaa gggtaaaaaa gatgcacata
    13681 atttttatgg ataaaaaatt tgatttcctc tgcatcttca atcgtaatca gccgtgtatt
    13741 caatggtatg aaatcgataa gactcttcat ataagttgtt ttaccggaac ccgttgctcc
    13801 ggcaaataca atggttttcc ctgctgctac ggcaagctcc ataaaagcag cgatatttct
    13861 cgctctgaat aaatcaagaa gctcatcatc gtatgtcctg tgtttttttc ctgactggac
    13921 ataatcataa aaaccgttcg ccacatattc tttatgtgtt atctgccgtg tcgatggttt
    13981 acgtatagtg attgaaatag tatttctctc acatgcagga ggaaaaacga cctgtacacg
    14041 ttctcctgat tccagtgttg ctgaaagtaa tggcttggtc tcgccgattt catctccccg
    14101 aaatgatgcc agcgtatgag aaaaacgttt acaaaaatca aaggtcacac tgtcattatt
    14161 atggaatgtc cagtcaccat taatttccgt ccagatttca ccaggacggt tgacagcaat
    14221 ttctgttagc ccttcaatat caagaaaaga ctggaatact tgatttttat aaaaatcgag
    14281 cgatttattg ctaatgctga caggaataac gccactcata ctattttacc tttaactcat
    14341 agatatcaga aaaatcaatg tcttccccga ccataatagt gattatgtca ccctggtttt
    14401 tatacattgt tggaggaata tttatcgaat tctcaagtgc gactttagcc atttcagcca
    14461 ttgcctgtcg tgagttttcg gtataatcca cattacgatc tttaccaggt gcattatccg
    14521 ccgccgccgc cgctacatcc tgaaccatac tgagcataag agaaccacca aaacgctccc
    14581 agaagtgaga atcgatccat ccatcaatgc ccgcttctcc caggggacca gctgctgctg
    14641 tatttaccat atcgattcgt ttattatcag gcgtccgcaa ctgctcccac ataacgaaca
    14701 ttctgccctg tccatgattc agcgttccgg tctggtaacg accaaaagcc ttagttccct
    14761 gttccagtaa ttttgtgtgg tgattagcac tccatacatc ttctgtaaaa acacaactga
    14821 tacgacctgc aacatcagaa acaaagcgtg tggttaaagc acacggtata agcctgtttt
    14881 cctcaatata gagatcagga tcgagattaa tcgcagttac tttcattcct gatttaccag
    14941 gcacattttc ttttgattct ttcctttctt cctgtggctc tgatgtctgc gatgtcctgc
    15001 tgctgccact cgcgccagtc tgactccctc cctgaccagc aacaggtatt gacaaatatt
    15061 tcctgaaccc ctcctgtggc acttctttat gaccgtcaga aacagtatta ccagaaccag
    15121 tagcgcctgg attgataatt gctttgttct caacagggtc aaaattctga ccaagaccag
    15181 tacggatttt acttacctga gaaatgctgg tatcgcctgt tgattctgat gctttctgct
    15241 ggtcatctgc aaaataattt ttatatgttt tcagcgcaaa aataccaata actaatacag
    15301 ccatcagacc aaacagaaag ccagaacgca tacgattatt tttgttcctg atatcaccga
    15361 tatcatgaac gggtttactt tccagctttg actgattcgc atcatcaact aaatcatctg
    15421 tttttttcat atcagtcatt attcacctca acacgttcta ccgcaggaga agatgtattc
    15481 ctctggtcgg ttaatacttt tccgaaagat ttattcacaa caccaacaac gctgtttcca
    15541 tagcgtaaaa caaatttgtc attaacgttg tggataacca taattttata cttgcctttt
    15601 gtttccacat taaaagcaag tgtctgttcc tgaccatctc ttacagcaaa tggagctggg
    15661 aatactttcc ctgagttaaa acctaaaaag gtaaatatgc cattatcata agcaaaatca
    15721 ggggcgatac gacgactgtc atatttttca ttgactcgca tgaaataatt ccagttttta
    15781 ggcgcatcgg ctttttcaaa actttcagaa atcagtttct tctgtctgag tttttcctgt
    15841 ttttcttttg ccagccttac ttcttctgca ttctttttcg ctatttctga tggatagcgg
    15901 aattgtacaa cataagcagg ttgcgcttgt ttttcttctg acagaaggat tagatccaga
    15961 ctgtaaatcc gctttgttgt tctgacaaaa agattcgtat cccattcctt ttctgttggc
    16021 tggaaaacct ttttcagttt ttcgccttca tcgccttcct gttcctgaac aacgggacgc
    16081 ggattgatgt aaacaacatt atcatcggtt gtgatttccc atccggcagg aaaaccagcc
    16141 tttgcactga taacagcctc accttcatca aaaacaactg atgtgagaaa tcctgtcttt
    16201 gaccggataa cggtcgtatt cgcaccgtta taactcacag tctgcatcct tgcatcaaat
    16261 ccagaaggta acggagtcgc tgctgaatac acaagcccag gaagcaataa acatgtagca
    16321 ataaataatt tcttcatcat tcccccctga cttcccgatc tgtctggtaa ctggttacag
    16381 taaaaccgag aggattaagc tcacgactgg aacttttaac cgacttttct ggttcaaaac
    16441 gatatgtcac acgagccgtc cagtatgaaa ctgaaacctg tccggtcgtg aagtttctcg
    16501 tcgttttttt aaagcgcaca gaggccagtt tatctggcgc ggttgcgtca gaaataatat
    16561 tggagatgac ctcaaccgca acgtaagaac cgttattatg ataaatttta tcaggagcca
    16621 tatcgctgtt atacagacga agataatcgt cctttactgt attcgagcta tatagctgta
    16681 cagtctcata atcatactga agagacggat aattataacc ttcacgtaaa gtaatatacg
    16741 tgtttacaaa ataccgccca agtgcttcag attgcaggat cttttcctgt ttaacctgag
    16801 taatcagttc tgtacggcct gttttttcgc caacagccac aatagcaagc tctttttctt
    16861 ttaatggcac aagaacacaa attgcagccc caagacataa ggacagtaat gatgctgcca
    16921 ctgcaacacg ccatgcattt ttcttagacc gttcattttc tgcatagagt tgtctttcga
    16981 aggatttagc tgtctcaatc ttcttttcga ttttttcact cataactgat tacctggctg
    17041 tggttaatgg gttccagttc gccggaaaca tcagaaggaa ggttattcct tgtggtacat
    17101 ccggaaatct gaaacaggaa aaacaaaaga atcacacatc gcataaattc accttattaa
    17161 gcgttcacga acacctttaa gagataaagg ccaagatgaa gaaaaagaat cccaccaata
    17221 agaagcaaaa agcgaagatc catacccttt ctccatttcc ccgcaagccc taaaccaagt
    17281 cttattcctg cgaagcaggt aaacactcct aaaagaagga ttaggacaaa ataaagtatc
    17341 atgacaaaat aatgaagcat gtcacaacca gctctgactg attccaccta agaccttaaa
    17401 taaggtaatt cccgtgatta aaataacaag ctgggttatt agctttctct tcctgctcca
    17461 tccggaggtg atatgtttat caacgaacac cagtatccag ttcagggaca tcacataaaa
    17521 aaaacgtttc attattttca tgcggcgttc ctcgctcgtg ctttttccag ggatgcaagt
    17581 cttctcgcct tcatccccaa agcacctgtc ggagccagcg cctgatatcc cttttcaccc
    17641 gcccattcag cggctgttcg cgcaccacgc cccatcagat tccctgcttt ccctgataaa
    17701 gaattcatgc ccgttcttcc ggccatccct aagccaaaac ctaaaccagc acgaccgcca
    17761 agcatcagag acttaccagt agccatacca gcagcaccca gccccatcat ggctgcgccc
    17821 tgaacagcac cttcaacacc tgcacctgct aactggacag caaaaccttt agctataaga
    17881 accaataaag cccccaaaaa cccagccata aagcccatag cacctgtaga tacaagattt
    17941 acattccctg tttgtgcagc acgaatagca tgggaaagga tcatcccttg aaaatccatt
    18001 gctatccgaa tcactaaact ggcaaataga actgtcagaa tactggagaa taacgattgt
    18061 aaccaattat taaacatgct ccgaataaaa ccaaacatga gacaaaagat aaatatcggt
    18121 gctgtaataa tcaggagttt catcgttaca tctgctgtta aaaaaacaac cacactaaca
    18181 gccattaaaa taagcgagcc agtccatatt aaaaactgac caactacacc ttgatcttta
    18241 acatatgttg atttatctaa agagtatatt tccgcaccaa gattttgcgt acttttccat
    18301 aagttatcta aagtttgcca gacactcacc cctccagaaa aaccatcttt catgccttgc
    18361 aacgcatcag tagccgcagt taaataccca tccgcattag ttataaacat gattatgatt
    18421 gcaaattttg atagatccca tactaaatcc tgcaagggcg tctgagtttt actggcaagt
    18481 atttgatatc ctttccatag tacatataac gtaaccgata ccgttgctaa cgacataata
    18541 tcattagcaa attgtgtttg ataactggag ctgattttat ctaccgaatc cataacggta
    18601 gaattatatt taacgaaaaa cccctgagcc atatatccac cttttaatca aaagttaatg
    18661 gttcagcttc tttctgctgt ttaataaagg cctcttgttc ttgtgtgacc aacatctcat
    18721 gatctgcttt atttttatta ttccagacat catactgcat ttttatcgcc tgcattttta
    18781 acgactgcgc ctgtaatgcg ttagccaaat cctgggattc tttgatatcc tttgaagcct
    18841 caattcggct acttaaactc tgaatctgag acattgcact tgataactgc ttattgatct
    18901 catttccctg ttcaatactg gcagccgttg acacaatccg tgctttacag agattatcat
    18961 tacgttcata gcccgtatta cacatatcga aggctccata cttgctgaac agatttttag
    19021 cctggctgct caatgcacct tcgggattac tggtaaaatc agaaatataa ctgttcccct
    19081 gcttataaat atttgtcagt tctgattgta gattacttag ttcatttgtg aatgccgcaa
    19141 tattccttat acctgttgcc gtggctaact ggtctttata tgcctgaatc tgactctgat
    19201 aatgttgcgc agtttcggac cattgtttga gtcgttctgt ccatcttgcg gcttcaacag
    19261 cccattccgg actggcatca atagcaaccg gaattcctgc gctactataa aatgaagccg
    19321 tcaataatga tatcagcatc aatgttttta cacgtttcat aaattcacct gtcagattgc
    19381 ccgttcgaga tattcaggaa cccagtcatc aggctccatt ccttcatgat aaatactttc
    19441 aaaaatttcc agattatctg cactggcaga caatattttc agatatccac caagtcccga
    19501 taaatcgagt gtcgcaagtg ctgaaaatga tttaccatcc ccctttttaa gactgctttt
    19561 tttaatcagg aactgtctcg acattggatc aagattttta acaatattaa attcttctgg
    19621 tgtcagctta agcccttcca cataatcatt gtaatcggca tcagggttag ccagataaat
    19681 actggtgctg catacttcaa ccacagcccg tgaaatctta ttcttcagta tttcatccgg
    19741 agactgagtt gccggaataa ccagcccgtt cagcttacga attgttttca gcttgttata
    19801 gacaaagtcg ctgaatgctt catcctgtag ccatttccag aactcatcca ggaagataac
    19861 aagacgccga ccgtccagaa gctgcgtaat gcgatacagc agatagaaag taattggtgc
    19921 acataccatc ggatcatcaa gaaactcggt gccatcaatg ccaaaattat tgacatgctg
    19981 aatattgaat gtgtctttag cattatcaaa aacccagcca tgagcctgac cattagccca
    20041 ttgggacaaa cgaaggataa tcccgttctc ctgctcatcc cgatcatctc tctgcataag
    20101 atgctcaagc attctggtaa tgccatattc ccgcatttcg ccaggaggaa aatccatcac
    20161 agcatcaaca ctttcgctaa taagcaatct ttctcttgtc gataatcttt caccatttct
    20221 ggtacacaga atctccatca gttgcttgac aaaaatacgg ttacgttttg ttgcctccag
    20281 agcaaaagga ttccatcctg tcggctcacc gctttttacg gtgtaatatt ccccaccaag
    20341 cattcggata cataattcag cccctctgtc cttatcaaga aagacacacg ttaacttctt
    20401 attttttgca gaatcagcaa aagtttcggg gttattgtat ttctgtaatg aacaggcaag
    20461 atatgacaga aacattgtct tacctgaacc cgccgttcct ataactttag tattagcaag
    20521 attcttttca cctgtttcat ctttaaacag tactgagtta tgtaaattca gataatacgc
    20581 ctgtttgctt ggtgttttga gaatagcaac cgcttctgtc cagcagtttt tatcgcgttt
    20641 cccctggtag aaattatgga atgatgccag ttcaacaaaa tttacattcg ataccggaga
    20701 taaacgcggc cttaaatgaa aaaccgccgg aagttgggca aaatatgccg ctggcaatga
    20761 catggttgac aatgccggaa taatgcccag gtcagtaaag tctgccgtaa ttttacttac
    20821 agattcgtca agctccctga tactgtccgc cattaccatt agcgtgaaat ggtagtaacc
    20881 aaaggatata tcaccggaca caatatcatt ttttgccttt tccagttcct gcaattgagt
    20941 aaccgcatca tcttctgtac tctttaactg tttttccgca cgtttaatgg tactcaatgc
    21001 ttctgatttg ctcatggatg tatatgaatg cgtaataata tagtcagcat cagaatactg
    21061 gagcacatca aaaacaccgg atgcagtctc actacagaaa tctttaattt caatagaacg
    21121 aaagaattta tttccatcaa tgcggcatat ctgtccggta tcatgattaa aaaatacatc
    21181 cactccacca agaacgttat acaccggaga atcagtgact ctgatttttt gcaacttccc
    21241 tgtcagaaga taattataga atgacagttg agaagaaaat acctttccgt tctcctcata
    21301 cataccaaga agtttacagg taaatttatc aagagcgcca gagaatgtat taatcatttc
    21361 attcattctc ttcacatgaa tgttaatatc atctttcttt tctttaatac tttttttgcg
    21421 tttttccagt ttttctacac gcccatctgg tctgtagatc agcgtaaagt aaagagtgtt
    21481 ccccttgaat ttatttttct tcatcgaacc atagtaacaa tctgatatta tatcagcata
    21541 tttattacct gattttgtgg taaaggcatc ataaaaactc gccctgcatg aatggttata
    21601 aaatgaaacg ggcagtccgg aaaatgaacg aacaagagtg gcaacctgtg agtcaatagt
    21661 ttctaacatc tccgcagaga ttgactcaaa gttaatcccc atcagttgcc atgtcgctac
    21721 ataatcaccg ttctttgttt tgacaatatt tttatcaaca tggcttgaat agggtatata
    21781 tttaccagta gtgattcgct cattcagttt catggcatta acaaactcat caatttcaac
    21841 agcttcatat tgtccggaga ggaacgctcg tgcgccaaaa aaacgattac acactgagtt
    21901 tccgagcatt ttcagcttaa gaaagtaaag gttaaaaatg tggtcgtcct gtttagtgat
    21961 cattctgaga acaaaaaccg cgacaggaat agccagccag atcagcttgc tgatataaac
    22021 ccccgccaga aataacgccc ctgcaaccac agtaagaggg acgacaggaa cacccacata
    22081 catagcaggg cgtgtcatcg ctttataaag tgtagacata ctatcgtccc cgctttatta
    22141 gttaaccatc attgatgcaa cttcagccgc actggcgata acaattgccc cgatgatgat
    22201 aggtgagcat tcacgaatcg tgcttccacc aaacagaacc ttgtagccga cccacagaca
    22261 ggcaatagtc accgtgacca gtgaaaggcc actaagccct gttttaacct tttccagcag
    22321 tgtttccgct tttgaaaatc catccgcaaa ggccggtgat gcaactgttg ccccggcgac
    22381 tgccataact accttatttt tacgctgcat tacagcagtg acagatgaac tgatacgatt
    22441 acatactgat ttcttaaatg acattttata agtcctgtta attaataact tttgttggat
    22501 gtgagttatc aacaaaagca gatttcagaa tggtttcggg ccagataact gacgcattgt
    22561 gtgaacgatt ttttcgctgt tctcccccgt tgcttcttgt acctggtaca acatattttt
    22621 ttcgttccct gtataaccaa ttcgctcaac ataacttgta ttattaaatt ctttttcttt
    22681 tcgcttaccg ttactaaaat ttcctgtata gtaacaacta agcgcattct ccaggctcct
    22741 ccctcgttta taacaatcca cgataatctt ttcgaaaaca gacaagtttt cacacgaatc
    22801 aaggagtttt tctgcggacg tggaataaaa agaaaaatta ctgctggtaa tctgcatcaa
    22861 tccgacagaa taacgtcttt ttctgttttc aatttctctg ataactgtta gagcttcctc
    22921 cttacttttg ggcatatgac tgataacact tttgccatag ctaccgcgtt ccctttcagg
    22981 aataatttca gccacagcat aaggattgaa gccactctcg acccgtgcaa tatcatttat
    23041 cgtatccgga tgaactgacg ccgcacacag caacaaggct gggaataaag acgccatagc
    23101 taacgctcca tatatccatc aatacgcata ctctgcatta ataagtaaat aatttgcttc
    23161 ctcttactaa gcaaagatgt tttcgttttc tcttcgataa atgcattcaa cctgggatcg
    23221 agttttatcg tgacataaac ccctttttcc gatgacttat ctgatttctc cttcatttaa
    23281 tcaatccact ataagtgtgt tttggatttg ttttagatgc gaacatgatt cgcaaaataa
    23341 caatgctcaa caatacgatc aaataacatt gacaaaatgg tcatattatg attcgtgtga
    23401 tcatgcaaaa aaaagcgccc atatgggcgc tctagtatga ttgaaacatt agttaatcga
    23461 atgtagggac tggagcatcc ttctgagact gaataaacaa tgcttgttta acattcttac
    23521 agttctgaga atcagagcca gacttctcac actctgcctg cttttgttta gcttccgtaa
    23581 gatgctgccc ccaccaatcc acacttttta cttcttcact acaaccaaca acgaagaacg
    23641 gcaaagcaaa aagcagatat tttttcataa attccccctc tcactgatcc tggaaagact
    23701 tgacacgaga agggcattag tccgaatgag taccagtgtt ctgatccctg ccaacgagac
    23761 acctcccagt tcagctctta cagaatcgag atattttctg acagttgaag gctttagtcc
    23821 tttgaaatca gcaatttcat tcagggtata gccataagcg tacatcagaa taatgtcttt
    23881 ttgttgctca ctcaaatgtt cttcatcact aaaaatttga tgaagtccag aaatgcagat
    23941 agcatcatgc tcagtcatga taacctccct cgtaggttgt tgtgatcagc aggtgagcaa
    24001 agtagccgct ttgttcacct gcgccaaaat caaattaaaa tcccaggcct ttccagttcc
    24061 tctcttgctg tattcttagt tttttatgtt cttctgaatc ctttgtaaac ccgtgttcaa
    24121 gagcaaaccc gatattgtga ccttgctcat gttttctgga tagctgcttt ttaacgtcgc
    24181 tctcttccgg ctgcctggtt tcacgctcat gaacctgacg ttctctgttc cgctcaaggg
    24241 caatattttc aatctgccag ttattgcgat gcgtttccct gtagcctgca acagttccat
    24301 catcattaaa cattggacta cgtacaagcg taggagccag tttttttact ttgataagcg
    24361 ttcctggctg gagcttttca gactcgaaat gatttttcag gtctttaccc caaatcgtaa
    24421 cctgttttcc accttttaaa gtttcataag tgaggaaagg tgttcgtttt tcccctgcct
    24481 tattctgata tgaagtctcc ccaaaatcca ccaccttgta aacattccgg agtcttttcg
    24541 gattttcagc ctgtaatcgc tcaatctccc gtttacgttc gggatctttt ttccaggtag
    24601 cggtaacatc atatcccata cctttcagtt ttctatgaaa accgtttctg aacttcctgg
    24661 tttcagattt agtaagtctt aatcttcttc ctgtttcttc atcacgaagt ttaatattaa
    24721 catgtacatg aggatgatct tctttatcat catggtatac ggcaacgaaa gcatggtttg
    24781 gataagtctc tttaagaaat tctaccgtag ctttcagagc gtcttccctg cttactccag
    24841 cttctggtgg tggtgaaaag accatgtttt tcacatgatc gatgttttct ccacgatatg
    24901 tcctggagta atcatttcct ttagataaag ttgaagtaaa ctccctatta aagtcttctc
    24961 ctttccctgt ttgctctgaa ccttttccat cataacagta agcctcaagt tcaccattac
    25021 gggtaatgta atcaatacca tttttgatgc ctgcggctgt tttacctgag ccagtgattt
    25081 taaaagtgac ttcttttgta ggtgtccagg tatatgcttt cttgtccgca ccatgtctga
    25141 ctttatgatt aaaagccgat ttactggcat gtatatgtct tcccgataac ttaggagatt
    25201 tcggatcacg cccagtccct ttagcgcgtt taatacggta ttcctgttct acatacacac
    25261 ccataaatca cccaaatctg ttaacaacac tcttggttaa cgtttcaagt tttgaatcaa
    25321 tttgcttaca cagttcaatc acttcaataa cgtcttttct gaaatctgga tcgttaaccg
    25381 tacagaatct ttcacctttt atgataaaat gaatgttgcg accaacacga tctacagcag
    25441 ttgatagttt tttaagttcc ttaacttcat cagggtaaag acagacttca ctctttaaca
    25501 aagactgacg cacacgaata gcaatttctc tgctcatgct catgccgtga agagcagcat
    25561 tacgtttaac aagttctatt tcatgagggt aaagacgcac tgataccagc tttgctggtt
    25621 cattattaac tgggatgtta acaggcttgg tttcaatatt aagcacgtta tgcttagcaa
    25681 aagcattgat actggtaaat ccacttaaaa tagcgttatg ttctgcaaat tttaactcat
    25741 catcacttag cctgaacgct atcatcttca taagtcaccc caacagagcc tgcggcaggc
    25801 acaggcaaaa acatcgtttt tggacaatct gattcaaatg ttaacatttg acatcggatt
    25861 gtctatcctg cattgattgt accatatgtg gcactgtgcc tggctataaa atcgtcgctg
    25921 catatgtcca gatttcgttg ctgaaagatt ctttcgtctt cgaccatcag gcaaacgtat
    25981 agctgaaaga tttgtgaaag aaaaaacagg cctggcaggg ctgggaattg ttacggctga
    26041 agccgtaacg ctttttaagt cctcgctgcg ctgcggggct tccggcgcaa agcgcctccc
    26101 atgcccttac agggcataaa aacaagggca attaagcccc tgcgcgatga ttgctgactt
    26161 ctttttccag agccttatta acaaaggcat tcaacgataa atcttcttcc atcgccattt
    26221 ctgctacccg acgatgcagt tctggatcaa gcctgacgtt aaacacgcct ttaaacgggg
    26281 tatcaggttc ctttccatcc tccacacaag actgtaaata cagatcaaca gatgttttaa
    26341 actcctgttc cagttcagct aatgtagaag cctcataagt taccaggtcc cgaataaacg
    26401 ccagttttcc atacaggaca ttattttcaa aatcgggttc aaccgtgcct aaatatcctt
    26461 tatattttaa atgtttcata ataatccagc ctctttcaga ttctgtttaa ttgctttcag
    26521 cgtaccacct ttgatataac tttccggatg tggacgatgc attaatatgg tgtgattgat
    26581 ttcagcattg aaaaaccgca ctcttgaccc ctgcatttcc tttttgacat atcccaaaga
    26641 ggaaaacaaa acgaccagtt catcccattc aaacgttttt ttactgttta aaaactttgc
    26701 cagtagctta tctgttttcc ccataaatcc atcccctata gatatgcaac taattatagt
    26761 tacacatggc atttttgtca aaaaatacaa aggggcagaa agcccctttt tttatttaaa
    26821 acatttcata cccttgcaag tagtttaacc accaccggaa ttgatcccat tcgctaaatt
    26881 tcattgccgg aattctggtt tcccagcctt tgacaaggga atcagcaagc tgtacgatct
    26941 gccgcgttga catttaaaaa cctcattcag ttttgattgt cgataacgtg atcaggttgg
    27001 tggaacaacc tgatcacacc ttgaatagtc agtcattacc ctccttcttt tctatagtta
    27061 ctgtgtatcc gtaaagagtc aaaatgcgat aagcatccaa cgcctcacgc tcacttttaa
    27121 atgttctgac ttcgtgtaat cctttacctt tatcaaggga tacacaaaac tcataatctt
    27181 cttctacttc tatcttttta attaatttat caagttcggc taatgttcgt tttggctcaa
    27241 aaagaaatgt gcattgtaca atggcgttta aatcttcccg atcaagctct aacagagcat
    27301 cattataagc agctttaaaa cagcgattat tacgcagatc agatgcaaac tgcattgcgg
    27361 cttgttttaa cgttttcatg aatttccctt gcattgatgt taatagacaa tttcagaatc
    27421 aatattgaaa tttccagaaa atgcagggat gcccctgcat tcataatgct taacaaagac
    27481 actcaataaa atctttaaaa ctcaagcatt catcgccatc ttttaatgaa tcaaaatatt
    27541 tttcatattc gtccctgtag aaaaggacta aatcaacatc actctgctta agttcgccaa
    27601 actgaggaac aattccggct ttatagtcac gaattttatt gttatcagta aatatgacaa
    27661 catactgttg tccagtatcc ttatgcataa ggataatagt gcaaagcgtt actcgttcga
    27721 atgtgaaaac atgattagtg gttgaagtaa aaacagatga gcatttcatt ttaaatctcc
    27781 tgccctgctg ggctattgtg agaggggcca ttcccctttc gatgaaacaa taatacgacc
    27841 tttaagtcgt atttgcaagt tttctcccgt ttttttactc gataagtgat tgttatcacg
    27901 ttttttaatc cgcgtaagcg gatggaaggg gcgaacgaaa ataccagggc agcacaggag
    27961 ccacatcgcc ccgaagcgcg gcgcagccgc tgacgaacgt accagggtgc acaggccatc
    28021 ccttcaccct gcaaagccca actgaccagc aggccatgat tatgctgatt tgcgccgcag
    28081 aatgccgcag ttagcgcgag cgcaagcgag tttaccccgc cctggtgcat tgcagcatgg
    28141 cggggcgctg tactgcgcgt gtgagcgtca gcgagctacg agcgcaactc caggtactaa
    28201 tataaaacca tcacaggtca ttttattttg actccctttt gcagagcacg tattcaggat
    28261 gttctcctgc aagtaacaaa agaaactcaa actcaaccag tgacagactt tgactgtttt
    28321 gagtattaac ttcctctttt ttctgccagg ttcttagccc aacaccataa atatgactgc
    28381 attccttttg tgttaatcct gcttttaaac gtaatttttt tacattttca ggtgtattat
    28441 cgggtttcat ttaacataaa ctccttaatt aaattcttaa ctggcgtctc atcgtcttcc
    28501 cttaatccgg cacacgtaaa atcaatatgt tgtaattcat tctcattcag tacagcatca
    28561 tacaatgtaa ttttcgtagt tttgttcccg attttaacat ttgttctggc ttttatcctt
    28621 tttgtaagcc tgtaattgtc accttctttt tcaagaaaat aagtcacatc acctttattt
    28681 tttctcataa ctgtttcaaa taccctgtaa ttttaacaag ttgatctata ctcaagcccc
    28741 gaatctgtaa atcataactg tcgccctgtt cggtgacttt accgttcaat ccgttttcag
    28801 ctttaaagcc tgtcaatgcc ccataccagc tttcaagctg gacaagttgc gataacatac
    28861 ctttcaggat cagaatttcg tccttttttt ccacctggtg tttctcatac tcaatcgcct
    28921 gtaacacctc ctgcgaagca tttaccagaa tttttcgctc gatatcggct gcaatatcaa
    28981 cgggattccg ttttctggat aacgtgcaaa catgatgcgg actacgccag gaacgactat
    29041 ccacactccc caccacagaa aagcggtctt tttccatccg aatatgcaca gagtaatttt
    29101 taaactgcgg tgacgtcagt tttatacgag acgaacaatc atcaagtttg ttcacgcgcc
    29161 agccgttccc caggatacgg cagacaactt caaagacagg gtgatattgt tcaaaaaaag
    29221 agttcatctg tttccctttt tgctacgtgg ctgctgttcc cgtctttttg ggttcgatgc
    29281 cccaaaagac gggctggcta taatatcggg ggcttctcgc ccccgttctg gttacgctct
    29341 ggtttccacg cgttgccacc ctgtcgccct gcgctgtccg gttgtaccgt attttgcgcg
    29401 gatttcttct atcgtgtgtt cttcacgatt ccagtaactt ttatgttcgt ctggacgata
    29461 aaaccattgt tttttctttg ccgcccattt acacccgatt tcttttaaag tttccttatg
    29521 tgtaatggtt tctccactaa tccagaccca gttacctatc acttcaaata ccagaccaga
    29581 taaaccagaa agaacgttta atactttttc caggtcatca ccgtaattat atcgtgcatg
    29641 ttcatcagtg ctctggaact gatttatttt atcaatattt gccatcaata catcaaaagc
    29701 tgcatttacc gctttcatca gttcagcccc taacgggtta cgatctggat gatattttaa
    29761 agcggctttt ctgtatgctg ctttgatatc tttttcagtt aattcgccgg ataatccaaa
    29821 aacgtttaat gcttcctgga tattcatttt tttaatctcc tgccctgctg ggctattgtg
    29881 agaggggcca ttcccctttc gatgaaacaa taatacgacc tttaagtcgt atttgcaagt
    29941 tttctcccgt ttttttactc gataagtgat tgttatcacg ttttttaatc cgcgtaagcg
    30001 gatggaaggg gcgaacgaaa ataccagggc agcacaggag ccacatcgcc ccgaagcgcg
    30061 gcgcagccgc tgacgaacgt accagggtgc acaggccatc ccttcaccct gcaaagccca
    30121 actgaccagc aggccatgat tatgctgatt tgcgccgcag aatgccgcag ttagcgcgag
    30181 cgcaagcgag tttaccccgc cctggtgcat tgcagcatgg cggggcgctg tactgcgcgt
    30241 gtgagcgtta gcgaactacg ggcgcaatgc aggagaacta acagaacctc cctaaaacgc
    30301 tctgaatcgc attttaagcg atttttttca tttcgcatgg ttttcctcat ggttgtatcg
    30361 aacgaagcgg cagagcgcga ttcagggctt cttagtggaa gatccaaaaa ggatcaaata
    30421 acggatcata tgatctgaat ctctctggtt ttgagaaagg agataccgct cgccgcagcc
    30481 gaacggcagg agcgtagcga ctgagtgagc gaggaagcgg aattttgcga tgtgacatta
    30541 ggatcagtac gcacgaatat tatatttatt tcaataagtt aaagttaact agggacaaat
    30601 ttatggtctt gaaaattgag atacataagg catcaaatat tttttgatga ttttatgtta
    30661 ttgaaagtta tgagttttaa tgattgatga tgtttgtttt agcttgcggg taataatcat
    30721 cggggacaga tttatggtaa ggaaccatca tcgttgctgg ttttgttgag ttatccacag
    30781 ttcctgaata ttcgcacgca ttaaaagcct tatcttttct tgtttttctt aaaaacttaa
    30841 aaacttagag tagctctaat ttattgattt taagcgtgtt ttttgtctaa acatgagagc
    30901 ttcctcggtt aaacatgata acttcctcgg ttaaacatga gagcttcctc ggttaaacat
    30961 gagagcttcc tcggttaaac atgagagctt cctcggttaa acatgagagc ttcctcggtg
    31021 atatccacaa aatgtgtcat aagaatacta attcgttgtt ctttctggtg aatctatttt
    31081 gaatctgttg ttaatctgcc ttgaatccag tgtggatttt gagcatggat tacctttgtg
    31141 agataaatca cagatatgaa acatgagaag atactcggtt aaacatgata ttgattgtgt
    31201 tgtaatatca tgtttctggt gttaaagtct gattatcaag agtgttggaa caatgagaat
    31261 gacgacaaat aagacttccc tttctcgctt aacaaaagtg agacatcgaa atgaattgaa
    31321 ttcaacgctg tcaacattgc ctatggctgc taaaaaagtc ttatttttag ccatgtgcca
    31381 gataaactct aaaaatgaat tcgatgatga tcacatattt tatgtgacag ttgccgatta
    31441 cattaaatgg gttcaggtta agcctgatgc ggcttatctt gctttgaggg atggctctaa
    31501 tatattagat acgacgcttc ttaagctgaa acatgatgaa atattagaac tgagtagtga
    31561 tttgggattt aagttcacta aaagtaatgt acctgattca atgaatttga gtctgactgt
    31621 tttttctact tattacagga atgaaggtag agtggggatc aagtttacga aagaagcgaa
    31681 aagattttta tgtaaactta ttggtgaaga aaaacgttat acaacgcaag ttttattatc
    31741 tgttgttcga ctgacaagtg ttaatgctgc atcactatat caactcattc gtaaaatata
    31801 tagtaataat tctcgcgcga atagttttga aatgacaata gatgaactta aagatgaatt
    31861 gaatctttat acaatagggg cgggggtgaa ggattataag tatccagatt atcctgcttt
    31921 taaaagagat gttcttaata aatcagtaaa gaaatcatga aacatacgga agtaaagaac
    31981 ttaagtttcg tagtttcaga aaaaaattgg gagaaaagtt tataaattaa agttctctta
    32041 tacaattggt tatgagggcg ataccaggga agactcagag tttactaata tgtttgataa
    32101 aatgtaccca cctgaaaatt gaggtcataa caatatgaag gataatatcg tagattttca
    32161 aagaatcagg gacagcatga atgatcattc aaccgatgtt gcaaatgatg ccgtttattc
    32221 tgacaaaaag aaaatatcca ggttctttta tctgctgaca cctgtcagat accttctggc
    32281 tgcttccctt tatctggttg ttgttattcc attggggatt cttgcgggat ttcgtttctt
    32341 gttgcagttt ttaggcggta tcgcagtgat gggtttaact atcgcccggt acatgggtgc
    32401 agatgtcagt agttacgttg ttcttgctgc atggatcgcc ttaactgttt gtggttgcgc
    32461 agagcagatt tttgaatggt ggatcgaaag ccgttttgcg ttccgtcttt ttggtatcgg
    32521 gagaacgccg gaagaatgag cgccgatctt acagacagta aagaacaatg caggatagac
    32581 aatccgatgt caaatgttaa catttgaatc agattgtcca aaaacgatgt ttttgcctgt
    32641 gcctgccgca ggctctttta aaaggaatat gaaatgatat ttaaccgtaa taaaaaacga
    32701 gatgaacaac ataattctgc tgttgttttg ccatcagctg aaaatgtatt ctctgatttt
    32761 attaagaaca atccagcttt gacaaccaat gcttttacag ccattgggga ggttgattgt
    32821 tttactaaag tacccttact ctcaaataat gaatcagagt ttttaggcat tctttcacgt
    32881 aatattatac ctgattattc cgtttttccc aaaatacggc tcattgaatt tgttcgtcct
    32941 catggtagcg aggaagctgt aaaagattta atccgtgaag tgcagaatat aacctgtgat
    33001 tttgtcctga aatcatatga tgaaacagtc ctggctgtta tccagtttgg tgaaaccgca
    33061 accgtcagac agcaaaagaa aaaactgatt atccagcgcg tgtgtgctat gacaggaatt
    33121 tcttttttcg aatttaaaaa cactgtcgat atgatgggga gcgaagattt ttgtcagttc
    33181 ctgcgggatg atgaagagta attaaaaata agcccacata tttgcgggct taacaggctc
    33241 tttattagta cttgctgcat ttgtgattac tggcaacaca gttttcactg
//
