LOCUS       NZ_CP068975             6635 bp    DNA     circular CON 16-MAY-2024
DEFINITION  Klebsiella pneumoniae strain fekpn2511 plasmid pfekpn2511-3,
            complete sequence.
ACCESSION   NZ_CP068975
VERSION     NZ_CP068975.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN17506720
            Assembly: GCF_016800965.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 6635)
  AUTHORS   Hu,L.M., Zhang,X.T., Zeng,X., Chen,Y., Liu,L. and Li,G.Q.
  TITLE     Genomic Characterization of a Carbapenemase-Producing, Extensively
            Drug-Resistant Klebsiella michiganensis Strain from a Renal Abscess
            Patient
  JOURNAL   Microbiol Resour Announc 11 (12), e0082522 (2022)
   PUBMED   36321904
REFERENCE   2  (bases 1 to 6635)
  AUTHORS   Zhang,X.T.
  TITLE     ESBL klebsiella pneumoniae
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 6635)
  AUTHORS   Zhang,X.T.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JAN-2021) Clinical Research institute, University of
            South China, 35 Liberation Ave., Hengyang 421001, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: unicycler v. 0.4.8; SPAdes v. 3.1.14
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50.0x
            Sequencing Technology             :: Illumina MiSeq; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016800965.1-RS_2024_05_16
            Annotation Date                   :: 05/16/2024 03:54:16
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,427
            CDSs (total)                      :: 5,302
            Genes (coding)                    :: 5,153
            CDSs (with protein)               :: 5,153
            Genes (RNA)                       :: 125
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 88
            ncRNAs                            :: 12
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 72 of 149
            Pseudo Genes (incomplete)         :: 82 of 149
            Pseudo Genes (internal stop)      :: 37 of 149
            Pseudo Genes (multiple problems)  :: 29 of 149
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP068975.1.
            Bacteria and source DNA available from Xiaotuan Zhang, The Second
            Affiliated Hospital, University of South China, 35 AVE. jiefang,
            Hengyang, Hunan province.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..6635
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="fekpn2511"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="pfekpn2511-3"
                     /geo_loc_name="China:Hengyang, Hunan"
                     /lat_lon="26.89 N 112.57 E"
                     /collection_date="2019-12-25"
                     /collected_by="XiaoTuan Zhang"
     gene            complement(join(6467..6635,1..284))
                     /locus_tag="JN237_RS26965"
                     /old_locus_tag="JN237_26965"
     CDS             complement(join(6467..6635,1..284))
                     /locus_tag="JN237_RS26965"
                     /old_locus_tag="JN237_26965"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)--rifampin ADP-ribosyltransferase Arr-2"
                     /protein_id="WP_000237816.1"
                     /translation="MVKDWIPISHDNYKQVQGPFYHGTKANLAIGDLLTTGFISHFEDG
                     RILKHIYFSALMEPAVWGAELAMSLSGLEGRGYIYIVEPTGPFEDDPNLTNKKFPGNPT
                     QSYRTCEPLRIVGVVEDWEGHPVELIRGMLDSLEDLKRRGLHVIED"
                     /name="NAD(+)--rifampin ADP-ribosyltransferase Arr-2"
     gene            457..1569
                     /gene="intI1"
                     /locus_tag="JN237_RS26970"
                     /old_locus_tag="JN237_26970"
     CDS             457..1569
                     /gene="intI1"
                     /locus_tag="JN237_RS26970"
                     /old_locus_tag="JN237_26970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 integron integrase IntI1"
                     /protein_id="WP_024166810.1"
                     /translation="MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVHWVRAFI
                     RFHGVRHPATLGSSEVEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEI
                     GRPRPSRRLPVVLTPDEVVRILGFLEGEHRLFAQLLYGTGMRISEGLQLRVKDLDFDHG
                     TIIVREGKGSKDRALMLPESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALERKYPR
                     AGHSWPWFWVFAQHTHSTDPRSGVVRRHHMYDQTFQRAFKRAVEQAGITKPATPHTLRH
                     SFATALLRSGYDIRTVQDLLGHSDVSTTMIYTHVLKVGGAGVRSPLDALPPLTSGHCCK
                     VSDEAAFCLIQRPYISKTLLTRRISPRGSP"
                     /name="intI1"
     gene            complement(1515..2219)
                     /locus_tag="JN237_RS26975"
                     /old_locus_tag="JN237_26975"
     CDS             complement(1515..2219)
                     /locus_tag="JN237_RS26975"
                     /old_locus_tag="JN237_26975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(2466..2939)
                     /gene="dfrA14"
                     /locus_tag="JN237_RS26980"
                     /old_locus_tag="JN237_26980"
     ARG             complement(2470..2939)
                     /name="dfrA14"
                     /gene="dfrA14"
                     /gene_name="trimethoprim-resistant dihydrofolate reductase
                     DfrA14"
                     /tool="amrfinderplus"
                     /drug_class="TRIMETHOPRIM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(2967..3805)
                     /gene="aadA1"
                     /locus_tag="JN237_RS26985"
                     /old_locus_tag="JN237_26985"
                     /pseudo=""
     ARG             complement(3018..3805)
                     /name="aadA1"
                     /gene="aadA1"
                     /gene_name="ANT(3'')-Ia family aminoglycoside
                     nucleotidyltransferase AadA1"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(3822..4622)
                     /locus_tag="JN237_RS26990"
                     /old_locus_tag="JN237_26990"
     CDS             complement(3822..4622)
                     /locus_tag="JN237_RS26990"
                     /old_locus_tag="JN237_26990"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032488483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxacillin-hydrolyzing class D beta-lactamase
                     OXA-10"
                     /protein_id="WP_000846390.1"
                     /translation="MKTFAAYVIIACLSSTALAGSITENTSWNKEFSAEAVNGVFVLCK
                     SSSKSCATNDLARASKEYLPASTFKIPNAIIGLETGVIKNEHQVFKWDGKPRAMKQWER
                     DLTLRGAIQVSAVPVFQQIAREVGEVRMQKYLKKFSYGNQNISGGIDKFWLEGQLRISA
                     VNQVEFLESLYLNKLSASKENQLIVKEALVTEAAPEYLVHSKTGFSGVGTESNPGVAWW
                     VGWVEKETEVYFFAFNMDIDNESKLPLRKSIPTKIMESEGIIGG"
                     /name="oxacillin-hydrolyzing class D beta-lactamase OXA-10"
     gene            complement(4887..6146)
                     /locus_tag="JN237_RS26995"
                     /old_locus_tag="JN237_26995"
     CDS             complement(4887..6146)
                     /locus_tag="JN237_RS26995"
                     /old_locus_tag="JN237_26995"
                     /function="4 : Transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001256773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloramphenicol efflux MFS transporter CmlA5"
                     /protein_id="WP_012300772.1"
                     /translation="MRSKNFSWRYSLAATVLLLSPFDLLASLGMDMYLPAVPFMPNALG
                     TTASTIQLTLTTYLVMIGAGQLLFGPLSDRLGRRPVLLGGGLAYVVASMGLALTSSAEV
                     FLGLRILQACGASACLVSTFATVRDIYAGREESNVIYGILGSMLAMVPAVGPLLGALVD
                     MWLGWRAIFAFLGLGMIAASAAAWRFWPETRVQRVAGLQWSQLLLPVKCLNFWLYTLCY
                     AAGMGSFFVFFSIAPGLMMGRQGVSQLGFSLLFATVAIAMVFTARFMGRVIPKWGSPSV
                     LRMGMGCLIAGAVLLAITEIWASQSVLGFIAPMWLVGIGVATAVSVSPNGALRGFDHVA
                     GTVTAVYFCLGGVLLGSIGTLIISLLPRNTAWPVVVYCLTLATVVLGLSCVSRVKGSRG
                     QGEHDVVALQSAESTSNPNR"
                     /name="chloramphenicol efflux MFS transporter CmlA5"
     ARG             complement(3826..4622)
                     /name="blaOXA-10"
                     /gene="blaOXA-10"
                     /gene_name="oxacillin-hydrolyzing class D beta-lactamase
                     OXA-10"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(4891..6146)
                     /name="cmlA5"
                     /gene="cmlA5"
                     /gene_name="chloramphenicol efflux MFS transporter CmlA5"
                     /tool="amrfinderplus"
                     /drug_class="PHENICOL"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(6468..6634)
                     /name="arr-2"
                     /gene="arr-2"
                     /gene_name="rifampin ADP-ribosyltransferase (Arr)"
                     /tool="rgi"
                     /drug_class="rifamycin antibiotic"
                     /identity="100.0"
                     /coverage="36.67"
     ARG             complement(4..284)
                     /name="arr-3"
                     /gene="arr-3"
                     /gene_name="rifampin ADP-ribosyltransferase (Arr)"
                     /tool="rgi"
                     /drug_class="rifamycin antibiotic"
                     /identity="100.0"
                     /coverage="62.67"
     ARG             complement(3015..3829)
                     /name="aadA"
                     /gene="aadA"
                     /gene_name="ANT(3'')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.62"
                     /coverage="103.04"
ORIGIN
        1 gtaagattcg gatcgtcttc gaacggtcct gttggctcaa ctatgtatat gtagccgcga
       61 ccctcgaggc cagacagtga catagcaagt tcagctcccc aaactgctgg ctccatcaag
      121 gctgaaaagt agatgtgctt aagaatacga ccgtcctcga aatgagagat gaaccctgtg
      181 gttagcaagt caccaatcgc caaattggct ttggttccat gatagaacgg tccttgcacc
      241 tgcttgtaat tatcatgaga gatgggaatc caatctttta ccattttaag acccttaatt
      301 gttgggattt ggctgcataa ctttgtttta gggcgactgc cctgctgcgt aacatcgttg
      361 ctgctccata acatcaaaca tcgacccacg gcgtaacgcg cttgctgctt ggatgcccga
      421 ggcatagact gtacaaaaaa acagtcataa caagccatga aaaccgccac tgcgccgtta
      481 ccaccgctgc gttcggtcaa ggttctggac cagttgcgtg agcgcatacg ctacttgcat
      541 tacagcttac gaaccgaaca ggcttatgtc cactgggttc gtgccttcat ccgtttccac
      601 ggtgtgcgtc acccggcaac cttgggcagc agcgaagtcg aggcatttct gtcctggctg
      661 gcgaacgagc gcaaggtttc ggtctccacg catcgtcagg cattggcggc cttgctgttc
      721 ttctacggca aggtgctgtg cacggatctg ccctggcttc aggagatcgg aagacctcgg
      781 ccgtcgcggc gcttgccggt ggtgctgacc ccggatgaag tggttcgcat cctcggtttt
      841 ctggaaggcg agcatcgttt gttcgcccag cttctgtatg gaacgggcat gcggatcagt
      901 gagggtttgc aactgcgggt caaggatctg gatttcgatc acggcacgat catcgtgcgg
      961 gagggcaagg gctccaagga tcgggccttg atgttacccg agagcttggc acccagcctg
     1021 cgcgagcagc tgtcgcgtgc acgggcatgg tggctgaagg accaggccga gggccgcagc
     1081 ggcgttgcgc ttcccgacgc ccttgagcgg aagtatccgc gcgccgggca ttcctggccg
     1141 tggttctggg tttttgcgca gcacacgcat tcgaccgatc cacggagcgg tgtcgtgcgt
     1201 cgccatcaca tgtatgacca gacctttcag cgcgccttca aacgtgccgt agaacaagca
     1261 ggcatcacga agcccgccac accgcacacc ctccgccact cgttcgcgac ggccttgctc
     1321 cgcagcggtt acgacattcg aaccgtgcag gatctgctcg gccattccga cgtctctacg
     1381 acgatgattt acacgcatgt gctgaaagtt ggcggtgccg gagtgcgctc accgcttgat
     1441 gcgctgccgc ccctcactag tgggcactgt tgcaaagtta gcgatgaggc agccttttgt
     1501 cttattcaaa ggccttacat ttcaaaaact ctgcttacca ggcgcatttc gcccagggga
     1561 tcaccataat aaaatgctga ggcctggcct ttgcgtagtg cacgcatcac ctcaatacct
     1621 ttgatggtgg cgtaagccgt cttcatggat ttaaatccca gcgtggcgcc gattatccgt
     1681 ttcagtttgc catgatcgca ttcaatcacg ttgttccggt acttaatctg tcggtgttca
     1741 acgtcagacg ggcaccggcc ttcgcgtttg agcagagcaa gcgcgcgacc ataggcgggc
     1801 gctttatccg tgttgatgaa tcgcgggatc tgccacttct tcacgttgtt gaggatttta
     1861 cccagaaacc ggtatgcagc tttgctgtta cgacgggagg agagataaaa atcgacagtg
     1921 cggccccggc tgtcgacggc ccggtacaga tacgcccagc ggccattgac cttcacgtag
     1981 gtttcatcca tgtgccacgg gcaaagatcg gaagggttac gccagtacca gcgcagccgt
     2041 ttttccattt caggcgcata acgctgaacc cagcggtaaa tcgtggagtg atcgacattc
     2101 actccgcgtt cagccagcat ctcctgcagc tcacggtaac tgatgccgta tttgcagtac
     2161 cagcgtacgg cccacagaat gatgtcacgc tgaaaatgcc ggcctttgaa tgggttcatg
     2221 tgcagctcca tcagcaaaag gggatgataa gtttatcacc accgactatt tgcaacagtg
     2281 ccgtcctgcg aatatgtgag ttttgaccta atgagccaca aaaactcatt ttcgcccacg
     2341 ataatttttc tacttccttt ctttggaatg ctcatttcaa tattcacata acgtcgctat
     2401 caatcgcgga aaaggcgtag tgcgcgaagc gaacgaagct ttttgccgtc gattgcatag
     2461 ctttgttaac cctttttcca aatttgatag caatagttaa tgtttgaagt aaagtgttgc
     2521 tcaaaaacaa cttcgaaggt atttggaata ctcgggaaga aaacatcccc ctctggctcg
     2581 atgtcgatcg tcgataagtg gagcgtagag gccatgggta atgtttctcg gtaaatttct
     2641 ccgccaccag acactataac gtgaccggtg aattcagcta gcctgtccat ggcctcttcg
     2701 attgactgaa atacaactac attgtcatca tttgatgtcc aacctgagcg ggtaacgacc
     2761 gcgtatttcc tattggggag tgcgcccata gattcaaacg tcttgcgacc caccagaagc
     2821 cactgattgt aggtcaatgc tttaaaaagt agctgctccc ctttcgcgga ccagggtatg
     2881 tctggaccgc aaccaatcac gccgtttttc gctttcgcag ccatcaatga tactttcaag
     2941 gttctcatcc tgggttaacg cttgagttaa gccgcgccgc gaagcggcgt cggcttgaac
     3001 gaattgttag acattatttg ccgactacct tggtgatctc gcctttcacg tagtgaacaa
     3061 attcttccaa ctgatctgcg cgcgaggcca agcgatcttc ttcttgtcca agataagcct
     3121 gtctagcttc aagtatgacg ggctgatact gggccggcag gcgctccatt gcccagtcgg
     3181 cagcgacatc cttcggcgcg attttgccgg ttactgcgct gtaccaaatg cgggacaacg
     3241 taagcactac atttcgctca tcgccagccc agtcgggcgg cgagttccat agcgttaagg
     3301 tttcatttag cgcctcaaat agatcctgtt caggaaccgg atcaaagagt tcctccgccg
     3361 ctggacctac caaggcaacg ctatgttctc ttgcttttgt cagcaagata gccagatcaa
     3421 tgtcgatcgt ggctggctcg aagatacctg caagaatgtc attgcgctgc cattctccaa
     3481 attgcagttc gcgcttagct ggataacgcc acggaatgat gtcgtcgtgc acaacaatgg
     3541 tgacttctac agcgcggaga atctcgctct ctccagggga agccgaagtt tccaaaaggt
     3601 cgttgatcaa agctcgccgc gttgtttcat caagccttac ggtcaccgta accagcaaat
     3661 caatatcact gtgtggcttc aggccgccat ccactgcgga gccgtacaaa tgtacggcca
     3721 gcaacgtcgg ttcgagatgg cgctcgatga cgccaactac ctctgatagt tgagtcgata
     3781 cttcggcgat caccacttcc ctcatgatgt ttaactttgt tttagccacc aatgatgccc
     3841 tcactttcca tgattttggt gggaatggat tttcttagcg gcaacttact ttcgttgtct
     3901 atatccatgt taaaggcgaa aaagtaaacc tctgtctcct tctcaaccca cccaacccac
     3961 catgcgacac caggatttga ctcagttccc acaccagaaa aaccagtttt tgaatgcact
     4021 agatattcag gtgccgcctc cgttaccaaa gcctctttta ctattagctg gttttcttta
     4081 gatgctgaca atttatttaa atatagagac tctagaaact ccacttgatt aactgcggaa
     4141 attctaagct ggccttccaa ccagaatttg tcaatgccac cactgatatt ctggttgcca
     4201 taggaaaatt ttttaaggta tttctgcatt cttacttcgc caacttctct ggcgatttgt
     4261 tgaaatacgg gaacagctga aacttgtatt gcccctctta aggtcaagtc tctttcccat
     4321 tgcttcatgg ctcttggctt tccgtcccat ttgaaaacct gatgctcatt ctttatgaca
     4381 ccagtttcta ggccgataat tgcgttgggg atcttaaatg ttgatgctgg aagatattcc
     4441 tttgatgcac gagctaagtc attggtagcg caggatttac tgctactttt acaaagcacg
     4501 aagacaccat tgacggcttc ggcagagaac tctttgttcc aagacgtatt ttctgtaatt
     4561 gaaccagcta atgccgtact cgaaagacac gcgataatta catatgcggc aaatgttttc
     4621 atggcacctt cttggtggct aacgttaatt cgacctcaga ggcgtttaag tcaaaatacc
     4681 tctgacgtct aacatgatta atcaaagtct gattttttaa caaaatcaga aagatagacg
     4741 cgaaacttta aaacaaaggc gtcaacactt caagtagcga tctttcgctt cggcgaggcc
     4801 taacgcctga gctcagccga ccgaaaccgc gtagcggttt tgggtcggct gcagcgattt
     4861 gttgggcgat agcttgccac attctctcaa cgattgggat ttgatgtact ttccgcactt
     4921 tgtagcgcga ccacatcatg ctccccctgg ccgcgagagc ccttcactcg ggaaacacaa
     4981 gacagaccga gcacgactgt tgcaagggtc aaacagtaca cgacaaccgg ccaagccgtg
     5041 ttgcgcggca acagcgaaat gatcaacgtt ccgatgcttc ctagcagtac accgcccaag
     5101 cagaagtaga ctgccgtgac cgttccagca acatggtcga atcctcgaag agcgccattg
     5161 ggcgacacag ataccgctgt ggcgacacca atacccacta gccacattgg agcaataaag
     5221 cctaacacgg actgcgaagc ccatatttcg gtgatggcaa gcaatactgc tccagctatc
     5281 aggcatccca ttcccattcg caagacactt gggctgcccc acttgggtat cacacgcccc
     5341 ataaaacgag ccgtaaacac catggcaatt gccactgtgg cgaacagcag gctgaagcca
     5401 agctgagaca caccttgcct gcccatcatt agtccgggcg caatggagaa aaagacgaag
     5461 aagctaccca ttccagcggc gtaacacaac gtgtacaacc agaagttcag gcacttaacg
     5521 gggagtagca gctgcgacca ttgcaagccc gcaactcgtt gcacccgggt ttcaggccag
     5581 aatcgccacg ctgctgcaga tgcagcgatc atgcccaaac ctagaaacgc aaagatagcc
     5641 cgccacccaa gccacatgtc gacgagcgct ccgagcaatg ggcctaccgc cgggaccatg
     5701 gccagcatgg atccgagtat gccgtaaatg acattacttt cctcgcgacc tgcgtaaatg
     5761 tcacgtactg ttgcaaatgt ggaaacaagg cacgccgagg caccacaagc ctgaagaatc
     5821 cgaagcccca gaaagacttc agccgatgac gtaagagcga ggcccattga cgccacaacg
     5881 taggcgaggc cacctcccag tagaacgggg cggcgcccca gtcggtccga tagcggtcca
     5941 aacaagagct gaccggcacc aatcatgacc aagtacgttg tcagcgtaag ctgaattgtg
     6001 ctcgctgtcg taccaagcgc gtttggcata aacggcactg ctggcaagta catgtccatg
     6061 ccgagtgatg ccaataaatc gaacggtgat aacaacaaca ccgtggcggc aagggagtac
     6121 cgccaactaa agttttttga gcgcacgaaa ccatctcctt gaacaaagga tttggcggcg
     6181 ctcccgtaga gcaaaaggat tcatgagaac gccgcaacaa ccgaaaaatg aaggttgctg
     6241 cggcttactt gtctgcgttc ttggaagtgc tcatctgctg actatctcat gattgaattt
     6301 gaatcgtaac aactttcaag caactctgcg aggagcctta ttgtgcgccc aacgccgcca
     6361 taaacggcga cagggtggcg cgcctattgc gcataaaatg gcgaagccat gcgcaacagg
     6421 cgcggaatct ctggcgtccg gtttgatggc tttgttatgc aaaggactag tcttcaatga
     6481 cgtgtaaacc acggcgcttt aagtcctcta acgaatccaa cattcccctt attaattcaa
     6541 caggatgccc ctcccagtct tcaacaacgc caacaattct caagggttcg caggttctat
     6601 aggactgtgt tggattaccg ggaaattttt tgttc
//
