LOCUS       NZ_CP068070            28553 bp    DNA     circular CON 06-FEB-2024
DEFINITION  Staphylococcus equorum strain FDAARGOS_1149 plasmid unnamed1,
            complete sequence.
ACCESSION   NZ_CP068070
VERSION     NZ_CP068070.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN16357318
            Assembly: GCF_016725305.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus equorum
  ORGANISM  Staphylococcus equorum
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 28553)
  AUTHORS   Sproer,C., Gronow,S., Severitt,S., Schroder,I., Tallon,L.,
            Sadzewicz,L., Zhao,X., Boylan,J., Ott,S., Bowen,H., Vavikolanu,K.,
            Mehta,A., Aluvathingal,J., Nadendla,S., Lowell,S., Myers,T., Yan,Y.
            and Sichtig,H.
  TITLE     FDA dAtabase for Regulatory Grade micrObial Sequences (FDA-ARGOS):
            Supporting development and validation of Infectious Disease Dx tests
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 28553)
  AUTHORS   Sproer,C., Gronow,S., Severitt,S., Schroder,I., Tallon,L.,
            Sadzewicz,L., Zhao,X., Boylan,J., Ott,S., Bowen,H., Vavikolanu,K.,
            Mehta,A., Aluvathingal,J., Nadendla,S., Lowell,S., Myers,T., Yan,Y.
            and Sichtig,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-JAN-2021) Institute for Genome Sciences, University of
            Maryland School of Medicine, BioPark II, 801 W. Baltimore St., Suite
            619, Baltimore, MD 21201, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: SMRT v. 8.0.0, HGAP v. 4, SPAdes v. 3.11.1
            Genome Coverage                   :: 1545.66x
            Sequencing Technology             :: Pacbio; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/06/2024 04:18:16
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,662
            CDSs (total)                      :: 2,576
            Genes (coding)                    :: 2,546
            CDSs (with protein)               :: 2,546
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 30
            CDSs (without protein)            :: 30
            Pseudo Genes (ambiguous residues) :: 0 of 30
            Pseudo Genes (frameshifted)       :: 16 of 30
            Pseudo Genes (incomplete)         :: 11 of 30
            Pseudo Genes (internal stop)      :: 10 of 30
            Pseudo Genes (multiple problems)  :: 6 of 30
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP068070.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..28553
                     /organism="Staphylococcus equorum"
                     /mol_type="genomic DNA"
                     /strain="FDAARGOS_1149"
                     /culture_collection="DSM:20674"
                     /type_material="type strain of Staphylococcus equorum"
                     /db_xref="taxon:246432"
                     /plasmid="unnamed1"
                     /geo_loc_name="Germany: Braunschweig"
                     /collected_by="DSMZ"
     gene            28..702
                     /locus_tag="I6J06_RS13060"
                     /old_locus_tag="I6J06_13055"
     CDS             28..702
                     /locus_tag="I6J06_RS13060"
                     /old_locus_tag="I6J06_13055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002498865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_115076074.1"
                     /translation="MKSVKMLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESATEDKQKKESDNINVESKSDTQIVEILKNQIDTLNDQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEEERHLNYSFDTSTNDR
                     QNVDAQEATYTTDSVNINQHQEEEKEAEIQHKDIDESKSDESTRYEETQPKKGFWSRLF
                     GG"
                     /name="DUF536 domain-containing protein"
     gene            906..1505
                     /locus_tag="I6J06_RS13065"
                     /old_locus_tag="I6J06_13060"
     CDS             906..1505
                     /locus_tag="I6J06_RS13065"
                     /old_locus_tag="I6J06_13060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009334164.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_236593618.1"
                     /translation="MKTNKQKMIINSSIKEFVKNGFDKASTNEIVKKANISKGSLFNYF
                     NSKKDLYIYLINYSTQILENMYREIDLSEKDLFNRIENIGLQKLYVQQKHPEIFDFLKH
                     SIQEESLEVKAIIEKKVDHIYENGRQKIFANIDYSKFRDDIDIEKAIEILNWTMSGFGE
                     KGLQQIKSFENISDFGNQYLKEWHDYAQILKNSFYK"
                     /name="TetR/AcrR family transcriptional regulator"
     gene            1557..2438
                     /locus_tag="I6J06_RS13070"
                     /old_locus_tag="I6J06_13065"
     CDS             1557..2438
                     /locus_tag="I6J06_RS13070"
                     /old_locus_tag="I6J06_13065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343783.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_056935283.1"
                     /translation="MREVVKITGLQKNFGDFKALNDVSFTVNKGEVLGFIGPNGAGKST
                     TLRTLLGVIKRDAGEVEIFGKDVWKESLKIHKRISYVPGDIALWGNLTGGEIIDLFMKL
                     HGSGDTEKRDELIKRFELDPKKKSKGYSKGNRQKVGLIAALSVDSDLYIFDEPTSGLDP
                     LMEVTFQEEVEKIKATGKSILLSSHILSEVERLADRVAIIRQGEIVETGTLDELRHLTR
                     STLMIETEEDVAKLSEIQGVFDFKQSNNQATFSADNKHLNSILSEAVKLGVKKLESTPP
                     TLEDLFIRHYEG"
                     /name="ABC transporter ATP-binding protein"
     gene            2464..4071
                     /locus_tag="I6J06_RS13075"
                     /old_locus_tag="I6J06_13070"
     CDS             2464..4071
                     /locus_tag="I6J06_RS13075"
                     /old_locus_tag="I6J06_13070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017795875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="WP_069819293.1"
                     /translation="MHEKFSGWNTLFLHYLKLDWKKMIIWILSIGLFSAGFVPAFKEIA
                     QGKGLIGMFETLQNPAMISMVGPTPIETATDYTLGAMYAHEMLLFCGLFAMIVSILHII
                     GHTRKEEELGLTELVRSFQIGRQANSLATIIEIVLINGLIAMFISAVMVSFNAETISLQ
                     GALLFGITIGMAGVMGASIALVVSQIMPTSSSAIGLSLGIVGLLYIIRAGTDVSNIELS
                     IFNPLGWTYLTYPFTDNNWLPIAIAFIFSIIVVIIAFMLEGARDMGDSYIPEKKGKRNA
                     KKSLLSIRGLLCKINQSIIISWLVAFMVMGIAYGSIYGDMQTFLESNEMMKQMFSTSNV
                     SIETSFTSTIMVVMVSLVAILPIVIVNKLFSEENKLHLSQIYPTKVTRSRIYWTNIGLA
                     FFSSVLGVLVASLSLGVTAINVMEGHGEMQLIDFLAAGYNFLPAILFFTSLATLAFGWA
                     PKLGKIAYAYLGYTFALNYFGGTLDLPEWLSKTAILNWLPQMPKENFDIFSFVILSMIS
                     IVFIILGYIGYKKRDLIG"
                     /name="tetronasin resistance protein"
     gene            complement(4225..4773)
                     /locus_tag="I6J06_RS13080"
                     /old_locus_tag="I6J06_13075"
     CDS             complement(4225..4773)
                     /locus_tag="I6J06_RS13080"
                     /old_locus_tag="I6J06_13075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019469005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_069819292.1"
                     /translation="MNFIVWLIIFCEVAFWVVILLGLVTRYILKQKTLGLLFLALTPVI
                     DLIILITTSIDLMNGATAEIPHAIAAVYISVSLVFGKSMINWADDRFRYYVMKQGSKPY
                     KAVGLAYAKNYAKSWLKHLLSYIIGTGILHLIVFLINDKSRTEAIDNVIHVWTIVIIID
                     LIICISYFLWPPKKKVNHN"
                     /name="hypothetical protein"
     gene            complement(4787..5368)
                     /locus_tag="I6J06_RS13085"
                     /old_locus_tag="I6J06_13080"
     CDS             complement(4787..5368)
                     /locus_tag="I6J06_RS13085"
                     /old_locus_tag="I6J06_13080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001124173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator C-terminal
                     domain-containing protein"
                     /protein_id="WP_107517820.1"
                     /translation="MPKIINHKEKKKQIIQYAFDSIVENGAKGSTVRQIAKLAKMTPGQ
                     IRYYFPNHSELLNAVMSAIELKVRRKIEVIFTSEDLNAIDKAKVSLLTVLPLDQERLAD
                     MEVWMAFRYDIHEYGQSTLDDGLDQLCHSVLTLLSNDHLLKDNLNIHLHSMKLHALIDG
                     LALHKLLNPNQTSNEDIQSIVDEEITRLTQ"
                     /name="TetR family transcriptional regulator C-terminal
                     domain-containing protein"
     gene            5787..7253
                     /gene="msr(A)"
                     /locus_tag="I6J06_RS13090"
                     /old_locus_tag="I6J06_13085"
     ARG             5788..7250
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="99.18"
                     /coverage="100.0"
     gene            7595..8494
                     /locus_tag="I6J06_RS13095"
                     /old_locus_tag="I6J06_13090"
     CDS             7595..8494
                     /locus_tag="I6J06_RS13095"
                     /old_locus_tag="I6J06_13090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000196697.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            8816..10276
                     /locus_tag="I6J06_RS13100"
                     /old_locus_tag="I6J06_13095"
     CDS             8816..10276
                     /locus_tag="I6J06_RS13100"
                     /old_locus_tag="I6J06_13095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019375671.1"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="WP_069828349.1"
                     /translation="MNNNKHQKYEYLADDPNFKTLPIILSLIIGAFFAILNETLLNIAL
                     TSLMKEFDITLPTVQWMTTGFMLIMGIVAPISALLLQWFTTRQLFLSTMTIFTLGTVIC
                     AAAPAFPILLIGRFIQAIGTGMLLPIIFNVFLLIYPPFKRGKIMGIVGFVIMFAPTIGP
                     TLSGVIVEYLGWRSLFIMVIPFSIFSIAFASKFLINVSEVTKPKIDYLSLVFSTIGFGA
                     VIYGFSSAGKSESGFLSINVLIPIIVGIIGIVLFSIRQLNLKEPLIDLRVFKYPMYTHA
                     ILMFLIIIMTMFASEIILPIYMQGPLALTAATAGLILLPGSLLNGAMSPFMGYLFDKFG
                     PRVLMIPASIVLSGAMYVMSRLNVDTPLWIVILSYILLMLSVSAIMMPAETNGLNQLPK
                     HLYPHGTAVMTTLQPVAGAIGVAVFVSIMNARQLQFLQNSGKPQDPDTINQAMVAGVEL
                     VYFISFSISIIAVILSFIVYRATPKKTD"
                     /name="MDR family MFS transporter"
     gene            10580..10879
                     /locus_tag="I6J06_RS13105"
                     /old_locus_tag="I6J06_13100"
     CDS             10580..10879
                     /locus_tag="I6J06_RS13105"
                     /old_locus_tag="I6J06_13100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002508712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002508712.1"
                     /translation="MVNSDKKEIEISKTNETRSNEISKMIEEGGLGADQYYTIDKQQPN
                     QKILIENIDQFKDEISQKDNDDLIDLLILNAQENINSKGNHALIIIKKELLSRM"
                     /name="hypothetical protein"
     gene            10958..11170
                     /locus_tag="I6J06_RS13110"
                     /old_locus_tag="I6J06_13105"
     CDS             10958..11170
                     /locus_tag="I6J06_RS13110"
                     /old_locus_tag="I6J06_13105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002508713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_069820938.1"
                     /translation="MKVKDQQPYILDNEQGSREEVEVREQRIKELEEDDEQEDKNQNNK
                     IIIFTTILIFILTIILSVIIQTNKK"
                     /name="hypothetical protein"
     gene            complement(11536..12381)
                     /locus_tag="I6J06_RS13115"
                     /old_locus_tag="I6J06_13110"
     CDS             complement(11536..12381)
                     /locus_tag="I6J06_RS13115"
                     /old_locus_tag="I6J06_13110"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaZ family penicillin-hydrolyzing class A
                     beta-lactamase PC1"
                     /protein_id="WP_000733283.1"
                     /translation="MKKLIFLIVIALVLSACNSNSSHAKELNDLEKKYNAHIGVYALDT
                     KSGKEVKFNSDKRFAYASTSKAINSAILLEQVPYNKLNKKVHINKDDIVAYSPILEKYV
                     GKDITLKALIEASMTYSDNTANNKIIKEIGGIKKVKQRLKELGDKVTNPVRYEIELNYY
                     SPKSKKDTSTPAAFGKTLNKLIANGKLSKENKKFLLDLMLNNKSGDTLIKDGVPKDYKV
                     ADKSGQAITYASRNDVAFVYPKGQSEPIVLVIFTNKDNKSDKPNDKLISETAKSVMKEF
                     "
                     /name="BlaZ family penicillin-hydrolyzing class A
                     beta-lactamase PC1"
     gene            12488..14245
                     /gene="blaR1"
                     /locus_tag="I6J06_RS13120"
                     /old_locus_tag="I6J06_13115"
     ARG             12489..14242
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.83"
                     /coverage="100.0"
     gene            14235..14615
                     /gene="blaI"
                     /locus_tag="I6J06_RS13125"
                     /old_locus_tag="I6J06_13120"
     ARG             14236..14612
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            14879..15472
                     /locus_tag="I6J06_RS13130"
                     /old_locus_tag="I6J06_13125"
     CDS             14879..15472
                     /locus_tag="I6J06_RS13130"
                     /old_locus_tag="I6J06_13125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690628.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNAYGCEKIFSDHISGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEEKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            15444..16886
                     /locus_tag="I6J06_RS13135"
                     /old_locus_tag="I6J06_13130"
     CDS             15444..16886
                     /locus_tag="I6J06_RS13135"
                     /old_locus_tag="I6J06_13130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mu transposase C-terminal domain-containing
                     protein"
                     /protein_id="WP_000790705.1"
                     /translation="MKNKEKYLTNFSEAKRKEATQKYNIIKPFILGKQSLSSISKSKGI
                     ALSTLYRWNKLYKEQGLTGLIHNTRVDKGEHKLKQNIIDEIKRLALKNKRNSIATIHRK
                     IANYCIENNFYKPSYKQVYSIIKAMPKSVIDFSHQGEKYYQNKYDLIQIRESSRPNEIW
                     QADHTLLDIYILDQKGNINRPWLTIIMDDYSRAIAGYFISFDAPNAQNTALTLHQAIWN
                     KNNTNWPVCGIPEKFYTDHGSDFTSHHMEQVAIDLKINLMFSKVGVPRGRGKIERFFQT
                     VNQTFLEQLPGYINNNDTSSDLIDFQNFEEKLRYFLIEDYNQKEHSAIQSTPINRWNSN
                     HFFPNMPSSLEQLDLLLLEIPKSRKIHSDGIHFQGFRYSNTNLTAYVGEYVLIRYNPND
                     MAEIRVFYRDEFLCTAISPDLADYSIDIKEIQHARSQRRKHLKQNIASPSTTDLIKEEK
                     SYGYSPQETTKNVKKLKRYRND"
                     /name="Mu transposase C-terminal domain-containing protein"
     gene            16879..17694
                     /locus_tag="I6J06_RS13140"
                     /old_locus_tag="I6J06_13135"
     CDS             16879..17694
                     /locus_tag="I6J06_RS13140"
                     /old_locus_tag="I6J06_13135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000164963.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWNTIEKQVNHRGWEDLASKTTDDILSVNKIFYTAPAEKQTRLSNDLYSISASIDL
                     GQKLHIVNKYGHDHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            17948..18499
                     /locus_tag="I6J06_RS13145"
                     /old_locus_tag="I6J06_13140"
     CDS             17948..18499
                     /locus_tag="I6J06_RS13145"
                     /old_locus_tag="I6J06_13140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002508682.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_002512562.1"
                     /translation="MAKIGYARVSTQDQSLDGQIDTLEEYGCERIFREKASGRKTKRTE
                     LDKCLDYLREGDILVIYKLDRLGRTTKQLIELSQWFDENSIDLHIIDMNVSTKDAMGKM
                     FFTMMSAFAELEANLLSERTKKGLEAARARGRKGGRPSLPDHKKREIKFLYDEQKLTGE
                     EIAKQTGVSRSTVYRIIKNN"
                     /name="recombinase family protein"
     gene            <18563..18886
                     /locus_tag="I6J06_RS13150"
                     /old_locus_tag="I6J06_13145"
                     /pseudo=""
     CDS             <18563..18886
                     /locus_tag="I6J06_RS13150"
                     /old_locus_tag="I6J06_13145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467786.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing protein"
                     /name="LysR substrate-binding domain-containing protein"
     gene            18997..19521
                     /locus_tag="I6J06_RS13155"
                     /old_locus_tag="I6J06_13150"
     CDS             18997..19521
                     /locus_tag="I6J06_RS13155"
                     /old_locus_tag="I6J06_13150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011304038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="WP_002508681.1"
                     /translation="MENYKFPSDSKIVSTDQVLINDLNNYNTLFGGVLMKKIDNNATLS
                     ARRHARVKECVTASTDSVEFLYPITQSDSVCIESYVVYTGEKSMEIFCKVISEDMITAE
                     RKIAAVAFLTFVALDEKKKPIKIPKISPQSKEEKLLFMDGEARAKMRKIKRSQTKNIID
                     SLDINKPWELE"
                     /name="acyl-CoA thioesterase"
     gene            19529..19903
                     /locus_tag="I6J06_RS13160"
                     /old_locus_tag="I6J06_13155"
     CDS             19529..19903
                     /locus_tag="I6J06_RS13160"
                     /old_locus_tag="I6J06_13155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002508680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002508680.1"
                     /translation="MINEMEELNQIKLDLKKLRNEFPSMYEKLEYIASLTRQLSIHYKY
                     LGALMFSDNRENIQNERPILIRESVLKLYEQEVAKVKKDSDFVFFKDMMLKFQNVDYSQ
                     IFLIILGAEPGFVFNNTIIK"
                     /name="hypothetical protein"
     gene            complement(20027..21064)
                     /locus_tag="I6J06_RS13165"
                     /old_locus_tag="I6J06_13160"
     CDS             complement(20027..21064)
                     /locus_tag="I6J06_RS13165"
                     /old_locus_tag="I6J06_13160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019236158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-butanediol dehydrogenase"
                     /protein_id="WP_107377004.1"
                     /translation="MKAAVWYGQKDVRVEDRKSKELQDNEVKVKVSWAGICGTDLHEYL
                     EGPIFISTDKPDPFLGQKAPVTLGHEFAGVVDDIGSKVTKFNKGDRVVINPTVSNREKE
                     ENIDLYDGYSFIGLGSDGGFAEFTNAPEENVYKLPDNVSDKEGALVEPTAVAVQAIKEG
                     EVLFGDTVAIFGAGPIGLLTTIAAKAAGASKIFVFDLSEERLNKAKSVGATHTINSGES
                     NPSDIISKYTDNGVDVAFEVAGVAPTLKSAIDVTKARGTVVIVSIFGHPIEWNPMQLTN
                     TGVKLTSTIAYTPTTFQQTIDLINEGNLKVKDVVTDEIELDDIVESGFKQLVNDKSQAK
                     ILVKL"
                     /name="2,3-butanediol dehydrogenase"
     gene            complement(21208..22083)
                     /locus_tag="I6J06_RS13170"
                     /old_locus_tag="I6J06_13165"
     CDS             complement(21208..22083)
                     /locus_tag="I6J06_RS13170"
                     /old_locus_tag="I6J06_13165"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_107377005.1"
                     /translation="MKNNFSKHIILDKLNFNRMHKNIEDINSIFSKKISEAIKDINSKY
                     SKKISESIEVLAKSIPNLDEFKDALDSFIDNTTTVNSIFINYDYPPIDYVDINEVINYV
                     EMNSNHQEVTKENINLIMTRYFDEIHFNHLKSQVTTYKLPQEDITILKEILDGYKHEYY
                     YLIIPALLARLEGMIFNSVNYKGRTNYRLFNIVIEETINKYKSKHDYYVDADYVKIKEY
                     YKFKLKRNFEFGEKRMNEINRHSIMHGYDNQYGTKQNAVILLLHFEYLYHCLAELNEND
                     KQDIRNKMLK"
                     /name="hypothetical protein"
     gene            complement(22142..22339)
                     /locus_tag="I6J06_RS13175"
                     /old_locus_tag="I6J06_13170"
     CDS             complement(22142..22339)
                     /locus_tag="I6J06_RS13175"
                     /old_locus_tag="I6J06_13170"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_071561892.1"
                     /translation="MLNYSDQQYAIIKSVLGENAYNRLIEDIEGVVKDKTNSISIKIPD
                     GGDFLFINTDSIAFINIDKQ"
                     /name="hypothetical protein"
     gene            complement(22557..22658)
                     /locus_tag="I6J06_RS13180"
                     /old_locus_tag="I6J06_13175"
     CDS             complement(22557..22658)
                     /locus_tag="I6J06_RS13180"
                     /old_locus_tag="I6J06_13175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002497230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_002495781.1"
                     /translation="MLDNFVHITTTAASGCIVALFAHWLRNRNDKKK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(23427..24017)
                     /locus_tag="I6J06_RS13185"
                     /old_locus_tag="I6J06_13180"
     CDS             complement(23427..24017)
                     /locus_tag="I6J06_RS13185"
                     /old_locus_tag="I6J06_13180"
                     /EC_number="3.2.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002468647.1"
                     /GO_function="GO:0019172 - glyoxalase III activity
                     [Evidence IEA]; GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase family protein"
                     /protein_id="WP_107517807.1"
                     /translation="MKNALFLLLDEFADWEGSYLSSTLNQSESWSVKTISVEEKVVSLG
                     GFSVLVDYVIGSEPKDYDLLIMIGGNSWDNSSDDLLRFVQETFNKGIPVGAICGAVDYL
                     AKNGFLNNYKHTGNSICLWSDYDCYTSANKFIEKQAVKDGKTVTANGTAPLEFTELVLK
                     LIEFDAPENIEKTMFINRHGFYNYCEKYGNPFL"
                     /name="type 1 glutamine amidotransferase family protein"
     gene            complement(24032..>24145)
                     /locus_tag="I6J06_RS13190"
                     /old_locus_tag="I6J06_13185"
                     /pseudo=""
     CDS             complement(24032..>24145)
                     /locus_tag="I6J06_RS13190"
                     /old_locus_tag="I6J06_13185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832602.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4260 family protein"
                     /name="DUF4260 family protein"
     gene            complement(24206..24412)
                     /locus_tag="I6J06_RS13195"
                     /old_locus_tag="I6J06_13190"
     CDS             complement(24206..24412)
                     /locus_tag="I6J06_RS13195"
                     /old_locus_tag="I6J06_13190"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_069813475.1"
                     /translation="MPSLFFFVAQVVAPIYSVVAHHVVPIYGVVAHIVQHSKNKKIVLF
                     ASINEWITYMFIWNFFFNNFNKV"
                     /name="hypothetical protein"
     gene            complement(25155..25703)
                     /locus_tag="I6J06_RS13200"
                     /old_locus_tag="I6J06_13195"
     CDS             complement(25155..25703)
                     /locus_tag="I6J06_RS13200"
                     /old_locus_tag="I6J06_13195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_107517809.1"
                     /translation="MNSKFKVFLYDLFISFLVTLIINFSVYFFSLKSISFDFLIKYKFY
                     FYWFVLFLFVLVIRFFIKKYIDRLQDDIPRIVMASYNKWFVKTDYLGFTWTVLFNFLSE
                     NWKNLDLQKCKFEDLEEVEICDVKGPYCPDDKREMKVTRTYFGRYKYKCPKCKYKKKLL
                     KNHITLVNDTIDEFRSKFR"
                     /name="hypothetical protein"
     gene            complement(26588..27016)
                     /locus_tag="I6J06_RS13205"
                     /old_locus_tag="I6J06_13200"
     CDS             complement(26588..27016)
                     /locus_tag="I6J06_RS13205"
                     /old_locus_tag="I6J06_13200"
                     /EC_number="2.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024812.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="WP_236593617.1"
                     /translation="MTQYQTWGPQSYEETQQFINVVLDKESNWIYNVLVDPDTDKVIGA
                     IQLAIDEVNQSAEINFIVHPNYWGDGVATDIAKTIIKYAFKVLKLNRIGAAIDSNNIAS
                     GIVLEKLGMKREGMLRKDKLVQDEYRDTLIYGLLRSEY"
                     /name="GNAT family protein"
     gene            complement(27191..28162)
                     /locus_tag="I6J06_RS13210"
                     /old_locus_tag="I6J06_13205"
     CDS             complement(27191..28162)
                     /locus_tag="I6J06_RS13210"
                     /old_locus_tag="I6J06_13205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017175392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_115076075.1"
                     /translation="MSRKNIKNQASQNFYMLHKVLFINEKYKKLSDSAKVTYAILNDRV
                     SLSIKNNWIDQNGDIYFIFTNENLQEVLDKSKNTITKIKKELQEVGLLEQVKTGFNRPN
                     KLYLHEIETNINIEKEIQNSTSNNDESSDSKESQIMGVQNPKQWEPRIPNNGSPESQNL
                     DSNDTDLSNTDYIETENNDTNDLNDTYNNPINNNHSDHTNHQQTEFNNDALKFQVLEEL
                     PQQLQDYLSKFEIREIRIIKSVLLKGKKSFNNAHDTYYRLEDVEFEIVSVLKRFKAMLL
                     QKNETVEAMQGYLMQSIKAEFEETHALYMRRQNMKQHNIFNQ"
                     /name="replication initiator protein A"
     ARG             7596..8491
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(11540..12381)
                     /name="blaPC1"
                     /gene="blaPC1"
                     /gene_name="BlaZ family penicillin-hydrolyzing class A
                     beta-lactamase PC1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             5788..7253
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.77"
                     /coverage="100.0"
     ARG             7596..8494
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             complement(11537..12381)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.09"
                     /coverage="100.0"
     Typing          29..657
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.393"
                     /coverage="85.0"
                     /evalue="0.0"
ORIGIN
        1 ataaacattt tataaagggt tgatgatatg aaaagcgtga aaatgttgag tgaagaatta
       61 ggggttagta agcaaacgat ttttaataac attaaacgat tgaatataga gacaataaaa
      121 caggaaaaca cttcgtttat taaagaagat accgatatag aaaaaatcat tcaaagagta
      181 aatgaaaata aaaagaaata tggttttgaa agtgctactg aagacaaaca aaaaaaagag
      241 tcagataata ttaatgttga atccaaaagt gatactcaaa tagtagaaat ccttaaaaat
      301 cagattgata ctttgaatga tcaaattgaa aaacaagaaa gtcgtcatga aacaacaatt
      361 gaattctaca gaaaagagtt gcaggaaaga tcaaaattgc ttgagaatca gcaagttctg
      421 gcattagaga gtaataaaaa aattcaaaag ttagagaatc aattagagga agagagacac
      481 cttaattatt cctttgatac atctactaac gatagacaaa acgttgatgc acaagaagca
      541 acatatacta ctgattctgt aaatattaat caacaccagg aagaagaaaa agaagcagag
      601 attcaacata aggatataga tgaaagtaaa agcgatgaaa gtacgcgata tgaagaaaca
      661 caacctaaaa aaggcttctg gagtcgtttg tttggtggct aataatagtt ttaaaagacc
      721 atattcatta aataagcgct acaagtcgaa taacttgtag cgcttattta tatcatcgga
      781 acttctgata atcatcgatt atgtaaaaaa ttgactactt tggtcatatg atgtaaactc
      841 caaatgaccg aagtagtcat tttgaatgaa aaggaggcat ttttattaac actatattta
      901 ataacttgaa aacgaacaaa caaaaaatga ttattaactc atcaatcaaa gaatttgtga
      961 aaaatggttt tgacaaggca tctacaaatg aaattgttaa aaaagcgaat atttccaagg
     1021 gatcattatt taattatttt aatagtaaaa aagacctcta tatttattta attaattata
     1081 gtacacaaat tttagagaat atgtatagag aaattgattt aagtgagaag gatttattta
     1141 ataggattga gaatattggt ttacaaaaat tatatgttca acaaaagcat cctgaaatat
     1201 ttgattttct aaaacattct attcaagaag aatcattaga agtaaaagct attattgaga
     1261 aaaaagttga ccatatatat gaaaatggac gacaaaaaat atttgctaac atcgactatt
     1321 ctaaatttcg tgatgatatt gatatcgaaa aagcaattga aattcttaat tggacaatgt
     1381 ccggttttgg agaaaaggga cttcaacaaa taaaatcttt tgaaaatatt tccgattttg
     1441 gtaatcagta tctcaaagag tggcatgatt acgctcaaat attaaagaat agtttttata
     1501 agtaaaagga agtattaaaa aaagaaacga gtactacaaa agggggcttc actattatga
     1561 gggaagttgt gaaaattaca ggattacaaa agaactttgg tgatttcaag gctttaaatg
     1621 atgtgtcttt tacagttaat aaaggtgaag ttttaggatt tattggtcct aatggtgcag
     1681 gaaaatctac tactttgcgt acactattag gagttattaa acgagatgca ggtgaggtag
     1741 aaatattcgg aaaagatgta tggaaagaaa gtcttaaaat tcataaaaga atatcttatg
     1801 ttccagggga tattgcatta tggggtaatt tgacgggtgg agaaattatc gatttattca
     1861 tgaaattaca tggtagtgga gacacagaaa aacgagatga gttaattaaa cgttttgaac
     1921 tagatcctaa gaaaaagtct aaaggatatt caaaaggtaa ccgtcaaaaa gttggtttga
     1981 ttgcagcatt atcagttgat tccgacttat acatctttga tgaaccgacc tctggccttg
     2041 atccattaat ggaagtaaca tttcaagaag aagttgaaaa aattaaagca actggaaaat
     2101 ctattttgct atcctcacat attttaagtg aggtggaacg tctagcagat agagttgcta
     2161 ttattagaca aggagaaatc gtagaaactg gaacactcga tgaattacgt catttaactc
     2221 gttcaacgct gatgatcgaa acagaagaag atgtagctaa attatcagaa atacaaggcg
     2281 tatttgattt taaacaaagc aataatcaag cgacattttc tgctgataat aaacacctta
     2341 attctattct aagcgaagca gttaaattgg gtgttaaaaa acttgaatct acaccaccta
     2401 cacttgaaga tttatttata cgtcattatg aaggctaaat aatggaaagg aggttgagtt
     2461 catatgcatg aaaaattttc tggttggaac acactgtttt tgcattatct aaagcttgat
     2521 tggaaaaaaa tgattatatg gattttaagt attggtttgt tttcagcagg atttgttcca
     2581 gcttttaaag agatagcaca agggaaaggg ttaattggta tgtttgaaac attacaaaac
     2641 cctgcaatga tttctatggt aggtcccaca ccaattgaga cagcaacaga ttatacttta
     2701 ggcgccatgt atgcacatga aatgttatta ttttgtggac tttttgcgat gatagtctct
     2761 atattgcata taattggaca tacacgtaag gaagaagaat tggggcttac agaattagta
     2821 cgctcgtttc aaataggtcg acaagcaaat tcacttgcta caataataga aatagtgtta
     2881 attaatggct taatagcgat gtttatttct gcagtaatgg tgagttttaa tgcagaaacg
     2941 atttctcttc aaggtgccct gctttttgga ataacaattg gaatggcagg agtaatgggt
     3001 gcaagcattg ctctcgttgt ctctcaaatc atgccaacct catcatctgc cattggattg
     3061 tctcttggta ttgtaggttt gctatatatt atccgtgctg gcacagatgt atccaacatt
     3121 gagttgtcta tttttaatcc tcttggttgg acatatctca cttacccttt tacagataat
     3181 aattggcttc cgattgccat tgcttttata tttagtatca tagtagttat tattgcattt
     3241 atgcttgaag gcgcacgcga tatgggagat agctatattc ctgaaaaaaa aggaaagagg
     3301 aatgccaaaa agtcattatt atctatccgt ggtttattat gcaaaattaa tcaaagtatt
     3361 atcatcagtt ggttagttgc atttatggtt atgggcattg cttatggatc aatttatgga
     3421 gacatgcaga ctttcttaga aagtaacgaa atgatgaaac aaatgttttc tacttcaaat
     3481 gtttctattg aaacatcatt tacgagcacg attatggtgg ttatggttag tttagttgct
     3541 atattgccga ttgtaattgt taacaaatta ttttcagaag aaaataaact tcatcttagc
     3601 caaatatacc ctactaaagt gacgcgtagt agaatatatt ggactaatat tggtttagca
     3661 ttttttagta gcgtattagg tgttttagtg gcttcactta gcctaggtgt gacagcaata
     3721 aacgtgatgg aaggtcatgg ggaaatgcag cttattgatt tccttgcagc tggatataat
     3781 tttttacctg ctatattatt tttcactagt cttgctactc ttgcattcgg gtgggcaccc
     3841 aaacttggaa aaatagctta tgcttatctt ggatatactt ttgcactcaa ttattttgga
     3901 ggtactttag acttacctga atggctttca aaaacagcta tattgaattg gctcccacaa
     3961 atgccaaaag aaaattttga tatcttcagt tttgtcattc tatctatgat tagcattgta
     4021 tttataattt taggctatat tggatataaa aaacgagatt taattgggtg aaattaaggt
     4081 tcgttattaa gatgaaattt gattatgtaa ataagaggct aatcactata taaaatgatt
     4141 agcctcttta tataacctat ttcttataaa tgcaaagaga taaatgatat taattagaat
     4201 aataagataa attcaaatta attgttaatt atgatttact ttctttttgg gtggccataa
     4261 aaaatatgaa atacaaatga ttaagtcaat aataatgaca attgtccaaa catgaataac
     4321 attatctata gcttctgtac gacttttatc attaattaaa aaaacaatca aatgcaaaat
     4381 acctgttcct ataatgtaag aaagtaaatg tttcaaccaa cttttagcat agtttttagc
     4441 gtaagctaac cctacagctt tataaggttt agatccttgt ttcatcacat aatatctaaa
     4501 tctatcatct gcccaattta tcatgctttt cccaaagaca agagatactg aaatatagac
     4561 cgcagctata gcatgaggga tttcagctgt tgctccattc atgaggtcta tacttgttgt
     4621 tataagtatt attaaatcta taactggtgt aagtgctagg aatagtagac ctagtgtttt
     4681 ttgttttaag atatatcttg ttaccaaccc gagtaatata acaacccaaa aggctacttc
     4741 acaaaaaata atgagccata ctataaagtt catgggttac cctcctttat tgcgttagcc
     4801 tagttatttc ttcatctaca attgattgaa tatcttcatt tgaagtttga tttggattaa
     4861 gtaatttatg aagagctaaa ccatcaatta atgcgtgtaa tttcatagaa tgaaggtgga
     4921 tgtttaaatt atctttcaat aaatgatcat tgcttaataa agttaaaaca ctatgacata
     4981 attggtctaa cccatcgtca agcgtacttt gaccatactc atgtatgtca tagcgaaacg
     5041 ccatccaaac ttccatatca gctaatcttt cttgatctaa tggtaatact gttagcaagc
     5101 ttacttttgc tttgtcaatt gcattaaggt cttcggatgt aaatattact tcaattttcc
     5161 ttcttacttt tagttctatt gcagacataa cagcatttag taactctgaa tgattcggaa
     5221 aatagtatct aatttgtcca ggcgtcatct tagctagttt cgcaatttgt cttacagtag
     5281 atcctttggc accattttct acaattgaat caaaagcata ttgaattatt tgttttttct
     5341 tttctttgtg attaattatt tttggcatat ttaaagttta acatttttta atacgactgt
     5401 gttaaataaa aatagtgggc tcaatttgta tttttagagc ctacctttgt taaacattta
     5461 aagattcttg taaaaaaacc aataaaatgt tatattaaca ttactatttt atcgatgaag
     5521 gaggattaaa atgacagctt ctatgagact caaataaacc tttttgaata caaaattaaa
     5581 ttaattcaaa aaggcttgtc cgcaatacac actcatagga tgacttatgt cattttttat
     5641 ccttcgatag gaataataaa cgctttcaaa tactaaaaca tcgtaataat tctttaagtg
     5701 tttgaaagtg taatgtgaat gagacgggag tagcctgtct cattttttgc gtacacgtcc
     5761 tttaaatata caaggagtgt ataaatatgg aacaatatac aattaaattt aaccaaatca
     5821 atcataaatt gacagattta cgatcactta acatcggtca tctttatgct taccaatttg
     5881 aaaaaatagc acttattggg ggtaatggta ctggcaaaac cacattacta aatatgattg
     5941 ctcaaaaaac aaaaccagaa tctggaacag ttgaaacgga tggcgaaatt caatattttg
     6001 aacagcttaa catggatgtg gaaaatgatt ttaacacgtt agacggtagt ttaatgagtg
     6061 aactccatat acctatgcat acaatcgaca gtatgagtgg tggtgaaaaa gcaaaatata
     6121 aattagctaa tgtcatatca aattatagtc cgatattact tttagatgaa cctacaaatc
     6181 acttggataa aattggtaaa gattatctga ataatatttt aaaatattac tatggtactt
     6241 taattatagt aagtcatgat agagcactta tagaccaaat tgctgacaca atttgggata
     6301 tacaagaaga tggcacaata agagtgttta aaggtaatta cacacagtat caaaatcaat
     6361 atgaacaaga acagttagaa caacaacgtc aatatgaaca gtatataagt gaaaaacaaa
     6421 gattgtccca agccagtaaa gctaaacgaa atcaagcgca acaaatggca caagcatcat
     6481 caaaacaaaa aaataaaagt atagcaccag atcgtttaag tgcatcaaaa caaaaaggca
     6541 cggttgagaa ggctgctcaa aaacaagcta agcatattga aaaaagaatg gaacatttgg
     6601 aagaagttga aaaaccacaa agttatcatg aattcaattt tccacaaaat aaaatttatg
     6661 atatccataa taattatcca atcattgcac aaaatctaac attggttaaa ggaagtcaaa
     6721 aactgctaac acaagtacgt ttccaaatac catatggcaa aaatatagca ctcgtaggtg
     6781 caaatggtgt aggtaagaca actttacttg aagctattta ccaccaaata gagggaattg
     6841 attgttctcc taaagtgcaa atggcatact atcgtcaact tgcttatgaa gacatgcgtg
     6901 acgtttcatt attgcaatat ttaatggatg aaacggattc atcagaatca ttcagtagag
     6961 ctattttaaa taacttgggt ttaaatgaag cacttgagcg ttcttgtaat gttttgagtg
     7021 gtggggaaag aacgaaatta tcgttagcag tattattttc aacgaaagcg aatatgttaa
     7081 ttttggatga accaactaat tttttagata ttaaaacatt agaagcatta gaaatgttta
     7141 tgaataaata tcctggaatc attttgttta catcacatga tacaaggttt gttaaacatg
     7201 tatcagataa aaaatgggaa ttaacaggac aatctattca tgatataact taaaaactat
     7261 acactaattt atattaaata tttctttaaa gtattataat aaagtaaata acaatagtaa
     7321 cataaccgat gatttataaa ttttttgtga tttaaaagtg tataatttta atgtcttcgg
     7381 tataaaaaca acgtgttcat aacgctcagg aactgcaatc attaataaac aaccattccc
     7441 agcactatca attaagaagt attattattt ataatattag aacataaatt actttcatac
     7501 actatatccc gaagtcttga agattaggtt catttatatc aatataaaaa atacgttcac
     7561 aagaaaaata taatagaaat aaggagccaa taaaatgact cgacataatg aaattattaa
     7621 atgtgcagaa aaatatcaat tacacatcca acctcaaaca atctcattga atgaatcggg
     7681 acttgatttc caagttgcat ttggaaaaga taaacatgga gtagaatggg ttttgagact
     7741 accaagaaga cctgacgttt ataaacgaac aaaacccgaa aaacaaacgg tagacttctt
     7801 acagaagaat gtttcatttg aaataccgaa gtggaaagta catgcaaaag accttattgc
     7861 ttacccaaaa cttacaggta aacccgcagc cacaatagat ccagaaatac aaaattatgt
     7921 atgggaaatt gaacacaaac cattaccaga aaactttatt aacacattag ctgaaacact
     7981 cgtagattta cacaacatac cagaagaaaa cattaacgtt cagcatataa atatcaaaac
     8041 catacaagaa ataaaaaatg actttcaaag aagaatgaat aaagttaaag aaacttatgg
     8101 cgtatcagat gaattatgga acagatggaa acaatggtta gaaaacgacg aactatggcc
     8161 tcgacatgcg accatgatac atggggactt acatccagga catataatgg tagataacca
     8221 agcaaacgtc acaggtctca tagactggac tgaagcaacc cactccgacc catcaatgga
     8281 ctttatagga caccatcgtg tattcgacga cgaaggatta gagcaactta taacagcata
     8341 cggtaaagct ggaggtgaaa tatggccacg aatgaaagag catataatag aactcaatgc
     8401 agtattccca atgtttatcg ctgagtttgc tatggaatca ggagaatcgg cgtatgaaac
     8461 gatggcattg aaagagttag gtatgaaaga gtagaactta tattaaaaga ggcccctttt
     8521 aaagacgaag gcaatcctga tgaaatttta aaacggcgtt taattagtga tggtctttgg
     8581 ttttctataa tgtattgaat atctcgacat ggaacaaatg caacaaatgg aaagaatcgt
     8641 tttcgaaatt tctaactcct taaatcagga ggataaataa acggtcattt tcattgaaag
     8701 cacttatata aatttcatca attttaatac ctaccgtaaa tacatttcat aagtattaaa
     8761 cagatgatta aaatttttag ttaatttaaa tatttatgat agagagggcc ttaaaatgaa
     8821 caataataag caccaaaaat atgagtatct agcggatgat ccaaatttta aaacattacc
     8881 cattatattg tcgctaatta ttggagcttt ttttgctata ttaaatgaaa cattattaaa
     8941 tattgccctt acatctttga tgaaagaatt cgatatcact ttaccaactg tacaatggat
     9001 gacgacaggg tttatgttga ttatgggaat cgtagcaccg atttctgcgt tgttgttgca
     9061 gtggtttact acaagacagt tatttttaag tactatgacc atttttactc ttggaacagt
     9121 aatttgtgcg gcggcaccag cctttcctat acttcttatt ggacggttca ttcaagcaat
     9181 cgggaccggg atgcttttgc ctattatatt caatgtattt ttgctgattt accccccctt
     9241 taaacgtgga aaaatcatgg gaatcgttgg gtttgttatc atgtttgcgc caactattgg
     9301 cccaacgcta tctggagtga ttgttgaata tctaggttgg cgttctttat ttattatggt
     9361 aatcccattt tcaatattct caattgcatt tgcgtctaag tttttaatta atgtatcaga
     9421 agttactaaa cctaaaatcg attatttatc attagttttt tcaactatag gttttggggc
     9481 tgttatatat ggctttagta gcgctggaaa aagtgaatca gggtttttaa gtatcaatgt
     9541 attaattcca ataattgttg gaatcattgg aattgtctta ttttcaataa gacaattaaa
     9601 tttaaaagaa cctctaatag atttaagagt atttaaatat cctatgtata cacacgctat
     9661 tttaatgttt ttaataatca tcatgacgat gtttgcttca gaaataattt tacctatcta
     9721 tatgcaagga ccattggctt taactgcagc tactgcgggg ttaattttac tgccgggcag
     9781 tttacttaat ggggcaatgt cgccgtttat gggatatcta tttgataaat ttggcccgcg
     9841 tgttttgatg attcctgcat caattgtgct aagtggggca atgtatgtga tgagtagatt
     9901 gaatgtggat acgcctttgt ggatcgttat tcttagttat atcttgttga tgctatctgt
     9961 ttcagcaatt atgatgcctg ctgaaaccaa tgggttaaat caacttccaa aacatttata
    10021 tccacatggg actgcagtga tgacaacttt acaaccagtt gctggagcaa ttggtgttgc
    10081 agtatttgtt agtattatga atgcaagaca gcttcaattt ttacaaaatt cagggaaacc
    10141 acaagatcct gacacaataa atcaggcaat ggttgcagga gttgaactcg tttattttat
    10201 tagcttttct atatccatta ttgccgttat cttatcgttt attgtttacc gagcgacgcc
    10261 gaaaaaaaca gattaattat ttaacaaata attatacatt ttaaaagtat gacttaacaa
    10321 taagacatag aaattcaaca agaaaaaatg aaattaaaaa cgatccttat taagatggaa
    10381 tttgtttttg aaacgattaa gaggcacctt ggttgaccaa ggtgcctctt tgatatgaat
    10441 tctaataata atcatctatg taaacgatac caagaatgtc atttattaaa ccctcaataa
    10501 attattagtg agcagagtta ttgttatttt aaatatgtat tattacactg tgtgtaatgg
    10561 gcatataagg gggatagtca tggttaactc tgataaaaaa gaaatagaaa taagcaaaac
    10621 aaatgaaaca cgatctaatg aaatatcgaa aatgattgaa gagggtggtt tgggcgctga
    10681 ccagtattac actatagaca aacagcaacc caatcaaaaa attttaatag aaaatattga
    10741 tcaattcaaa gacgaaataa gtcaaaaaga taatgacgat ttaattgatc tattaatact
    10801 aaatgctcag gaaaacatca actcaaaagg taaccatgct ttgattatta taaaaaaaga
    10861 actgcttagc cgaatgtaat aaaaatgaaa ttaaaaaaac tgagacacct aaatctttag
    10921 gtgtctttgt tgttctaata ataaggagaa aaaatttatg aaagtaaaag accaacaacc
    10981 ctatatctta gataatgagc aaggctcaag agaagaagtt gaagtacgcg agcaaagaat
    11041 taaagaatta gaagaagatg atgagcaaga agataaaaat caaaataata aaattattat
    11101 ttttacaact atactgatat ttattttaac cataatttta tctgttatta tacagacgaa
    11161 taaaaaatag ataaaatctt taaagttaaa aacgttcgtt tttgacacaa aacctcttaa
    11221 cttaatatta agagtgtcac tttgcttgat atatgagaat tatttaacct tataaatgag
    11281 aaaaaagcaa cgcactttaa ataagatacg ttgctttttc gattgatgaa cacctataat
    11341 taaactattc atctattatt tataattttt tgtatataca atatttctag tttgttaaag
    11401 agaattaaga aaataaatct cgaaaataat agagggaaaa tcagtttttg atatcaaaat
    11461 tatacatgtc aacgataata caaaatataa tacaaaatat aagatgttat cagtatttat
    11521 tatgcattta gaatattaaa attccttcat tacactcttg gcggtttcac ttatcaactt
    11581 atcatttggc ttatcacttt tattgtcttt attcgtaaaa atgactaaaa caataggttc
    11641 agattggccc ttaggataaa caaaagcaac atcatttcta gaagcatatg ttattgcttg
    11701 accactttta tcagcaacct tatagtcttt tggaacaccg tctttaatta aagtatctcc
    11761 gcttttatta tttaacatta aatcaagtaa gaattttttg ttttctttgc ttaattttcc
    11821 atttgcgata agtttattta aagtcttacc gaaagcagca ggtgttgaag tatctttttt
    11881 gctctttggt gaatagtaat ttaattctat ctcatatcta actggatttg ttactttatc
    11941 tcctagttct tttagacgtt gtttaacttt tttgattcca ccgatttctt ttataatttt
    12001 attgtttgct gtattatcac tatatgtcat tgaagcctca ataagtgctt ttaaagtgat
    12061 atcttttcct acatattttt ctaaaatagg agaataagca actatatcat ctttgttaat
    12121 atgtactttt ttatttaact tattataagg tacttgttct aacaaaatag cactatttat
    12181 cgcttttgaa gttgaagcat aggcaaatct cttatctgaa ttaaatttta cttccttacc
    12241 acttttagta tctaaagcat aaacaccaat atgagcatta tatttttttt ctaaatcatt
    12301 taactctttg gcatgtgaac tgtttgaatt acatgcactt aaaactaaag caattacaat
    12361 taaaaatatt aactttttca aaataaaccc tccgatatta cagttgtaat ttttataaat
    12421 caataatatt acaattgtaa tatcggtgtc aatagtttat tataaatatt tgaaagaagg
    12481 tgttgaaatg gctaagttat taataatgag catagtaagc ttttgtttta tatttctatt
    12541 gttattattt tttaggtaca tattaaaacg ctattttaat tatatgttaa attataaagt
    12601 ttggtatcta actcttcttg caggattaat tcctttcatt cctattaaat tctctctttt
    12661 taaatttaat aatgtgaata atcaagcgcc cacagttgaa agtaagtcac acgacttgaa
    12721 ccataacata aataccacca aacctattca agagttcgca acagatatcc ataagtttaa
    12781 ttgggattca attgataata tctgcacagt tatttggata gttttagtta ttattttaag
    12841 ttttaaattt ttgaaagcct tattatatct taaatattta aagaaacagt cactttatct
    12901 aaacgaaaat gaaaaaaata aaatagatac gatacttttc aaccatcaat ataaaaaaaa
    12961 tattgtgatt cgaaaagcag agactattca atctccaata actttttggt atgggaaata
    13021 tattattttg attcctagtt catattttaa aagtgtaatt gacaaaagac taaaatatat
    13081 aatattgcat gaatatgctc atgctaaaaa tagagatact ttacatttaa ttatctttaa
    13141 tatcttctct attattatga gttacaatcc attagtacat attgtaaaaa gaaagataat
    13201 tcatgacaat gaagtagaag ccgatagatt tgtccttaat aatattaaca aaaatgaatt
    13261 taaaacttat gcggaatcta ttatggactc cgtattaaat gttccatttt ttaataaaaa
    13321 tatattaagc cattcattta atggtaaaaa gtcattactc aaaagaagat taattaatat
    13381 aaaagaagcc aatctgaaaa aacagtccaa attaattcta atttttattt gtatttttac
    13441 ttttttgctc atggtaattc aaagccagtt tttgatgggg caatccataa ctgattataa
    13501 ttataaaaag cccttacaca acgattacca aattttagat aaaagtaaaa tttttggttc
    13561 aaatagtgga tctttcgtca tgtacagcat gaagaaagac aaatactata tttataacga
    13621 aaaagaaagt agaaaaaggt attctcctaa ttcaacttat aaaatttatt tagctatgtt
    13681 tggacttgac cgacatatta taaatgatga aaattcacgt atgtcatgga atcataagca
    13741 ttaccctttt gatgcttgga ataaggaaca agatttaaat acagcaatgc aaaattcagt
    13801 taattggtac ttcgaacgta ttagcgatca aataccaaag aactatactg cgactcaact
    13861 caagcaatta aattatggta ataaaaattt gggaagttat aaaagctatt ggatggaaga
    13921 tagtttgaaa atatctaatc ttgaacaagt aatagttttt aaaaatatga tggaacaaaa
    13981 taaccatttt agtaaaaaag caaagaatca attatcttct tcattattga ttaagaaaaa
    14041 tgaaaagtat gaactgtatg ggaaaacagg tacaggtata gtaaacggga agtataataa
    14101 tgggtggttt gtaggttacg taattacaaa tcatgataag tattattttg ctacacattt
    14161 atcagatgga aagccatctg ggaaaaatgc tgaattaatc agtgaaaaaa tattaaaaga
    14221 aatgggtgtt ttaaatggcc aataagcaag ttgaaatatc tatggctgaa tgggatgtta
    14281 tgaatataat atggggtaaa aaatcagtat cagctaatga aattgtagtt gaaattcaaa
    14341 aatataaaga agttagcgat aaaacgatta gaacattaat cacaagacta tataaaaaag
    14401 agattataaa acgatacaaa tcagagaata tttattttta ctcatcaaat attaaagaag
    14461 acgatattaa aatgaaaact gctaaaacct ttcttaataa actgtatgga ggggacatga
    14521 aaagtttagt gctgaatttt gcgaaaaatg aagaattaaa taacaaagaa attgaagaat
    14581 tgcgagacat tttaaatgat attagtaaaa agtaattaga gatatgtttc aaacataata
    14641 catatgtaaa ctatgcttga ctcttattaa attagttttg ttaataacat ttaaaatata
    14701 ttattaaaga tgagagtgta cagaaaataa ccattttctg tacactctct ttttatgccg
    14761 aaataagtga gtaatacata tattttcgtg ttcaaaaacc caacaaaaaa tctatgttca
    14821 caaaagacct tgaaattaag ttatggtaca ctgtatatgt atataggagg tttgtatttt
    14881 gaaaataggt tatgcaagag tttcaactgg attacaaaat ctgaatttac aggaggaccg
    14941 attaaacgca tatggttgtg aaaagatatt tagcgaccat attagtggtt caaaaagtaa
    15001 aagacctgga ttagataaag caattgaatt tgcgagatca ggagatacga ttgttgtttg
    15061 gagactcgac agactaggac gtaatatgga ggatttaatc acattagtta atgagcttaa
    15121 cgaacgaggt gtaagtttcc atagtttaga agaaaatata acgatggata aatcaagttc
    15181 tacaggacaa ttattatttc atttattcgc agcgtttgca gaatttgaac gaaatttaat
    15241 tttagaacgt tcttcagctg gccgaattgc agcacgtgct agaggacgct atggaggtag
    15301 acccgaaaaa ttaaatcaaa aagatttaaa cttacttaag acactttatg ataatggcac
    15361 gccaattaag acaattgcag agcagtggca agtttcacgt acaacgattt atcgttacct
    15421 caataaattg gaggaaaagg aagatgaaaa acaaggagaa gtatctaact aatttttctg
    15481 aagccaaacg taaagaagct actcaaaagt acaatattat aaaacctttt atcttgggca
    15541 agcaatcttt atcaagcatt tctaaaagca aaggtattgc gttaagtaca ctttataggt
    15601 ggaataaatt atataaggaa caaggtctta ctggtctaat tcataataca agagttgata
    15661 aaggtgagca taaattaaaa caaaacataa tagacgagat taaacgcctt gcactcaaga
    15721 ataaaagaaa tagtattgct acgattcata ggaaaatcgc taattattgt atagagaata
    15781 atttttataa accaagttat aaacaagttt atagtattat taaagcaatg cctaagtctg
    15841 ttattgattt ctctcaccaa ggtgaaaaat actatcaaaa taagtacgat ttaatacaaa
    15901 taagagaatc ctcaagaccc aatgaaatat ggcaagccga ccatactttg ctagatattt
    15961 atatattaga tcaaaaaggt aatatcaata gaccatggct aaccattatt atggatgact
    16021 atagtcgtgc aattgcaggc tactttataa gttttgatgc tcctaatgct caaaacacag
    16081 cattaacact acaccaagca atatggaata agaataatac caattggcca gtatgtggta
    16141 tacccgaaaa attctacaca gatcacggga gtgactttac ctcgcaccac atggaacaag
    16201 tcgctattga tttgaaaatt aacttgatgt tttcaaaagt tggtgtccct cgtggtcgcg
    16261 ggaaaataga acggtttttt cagacagtta accaaacttt cttagaacaa cttcctggat
    16321 atataaacaa taatgatact tctagcgatt taatagattt tcaaaatttc gaagaaaaat
    16381 tacgatactt tttaattgaa gattataatc aaaaagagca cagtgctatc cagagcactc
    16441 ctatcaatcg gtggaacagt aatcattttt ttcctaatat gccaagcagt ttagaacaac
    16501 ttgatttatt attattagaa atacctaaat ctagaaaaat tcattcagat ggtattcatt
    16561 ttcaaggctt tagatacagt aatacaaacc taactgctta tgtaggtgag tatgtattaa
    16621 ttcgttacaa tcccaatgat atggctgaaa tacgcgtttt ttatagagat gaatttcttt
    16681 gtacagcaat atcccctgat ttagctgatt attcaattga tataaaagag atacaacacg
    16741 cacgtagtca gagaagaaaa cacttaaaac aaaacattgc tagtccaagc accactgatt
    16801 taattaagga agaaaaaagt tatggttact cacctcaaga aacgaccaaa aacgtcaaaa
    16861 aattaaagag gtatcgtaat gactaaaaat cagaatttca ttgaaacgaa agagtataaa
    16921 cgatttgctg aattttgcga tgcttgtatc aaatatcaat atattgggat ctgctatggt
    16981 caacctggtg tcggaaaaac tttatcttct aggtattaca caaattggaa tactattgaa
    17041 aagcaagtta atcatagagg gtgggaagat ctagctagta aaacgactga tgatatatta
    17101 tcggtgaata agatatttta tactgcaccg gctgaaaaac aaacaagatt aagtaatgat
    17161 ctatatagta ttagtgcaag tattgatttg ggtcaaaaat tacacatcgt aaataagtat
    17221 ggtcatgatc atagtaaaca ttatagtgat atgtttaaat atattgattt aattatagta
    17281 gatgagattg atcgccttaa agtgcaacat ttagagcaat taagagctat ttatgatgaa
    17341 cataatttag caatgatatt tattggtatg ccaggtatag agaaaaaact atctcgttat
    17401 cctcaactat attcgcgtat aggttttgca catgaatttg ataatctaag taaagacgag
    17461 acgcatcata tattagaata taagtggcaa gatttaggat ttgatctaaa actcgaagat
    17521 tttactgatt atgaggcaat aacgacgatt attaaaatta caaaagggaa ttttaggctg
    17581 attcatcgtt tatttgcgca gatagataga attatggata taaatggctt agataaaatc
    17641 agtacagaag ttgtagaaac agctagagat agtttagtca taggtattcg ttaatagaaa
    17701 aagcaatgta ctttaatata ggacattgct tttctcattt actaggtaaa atcattctca
    17761 tatatcaagt aaagtaacat aagaggtttt tcttggatat ttaagtctat aaacttgtgt
    17821 tataatcaat gtatcataat tctcgaaaat tatgagtttt cagacgatga gagacgcgct
    17881 tatttgcatc gagaattaga tttcgttaat aagtacccat aaaacgatta aaagaggtgg
    17941 tatttaaatg gctaaaattg gttatgcacg tgtatcaaca caagatcaaa gtcttgatgg
    18001 acagattgat acacttgagg aatatggttg tgaacgtatc ttcagagaga aagcgagtgg
    18061 tcgcaaaacg aaaagaacgg aacttgataa gtgtttggat tatttacgag aaggagatat
    18121 tctagttatc tataaactag atcgtcttgg acgtacaacg aaacaattaa ttgagttatc
    18181 tcaatggttc gatgaaaaca gcattgattt acatattatt gatatgaatg tatcgaccaa
    18241 agatgcaatg ggtaaaatgt tctttaccat gatgagtgca tttgctgaac ttgaagctaa
    18301 cttattaagt gaacgtacga aaaaaggatt agaagcagca cgagcaagag ggcgaaaagg
    18361 cgggaggcct tcattacctg accataagaa aagagaaatt aagtttctat acgatgaaca
    18421 aaaacttaca ggagaagaaa ttgctaagca aactggtgta agtcgttcaa cggtatacag
    18481 aataataaaa aataattagt ttaaacaact ggtaacgtga agaaataata aaaactttaa
    18541 taaattctct tttttagaag aacaagaatt tattttattt aattctgatt tctgtttaaa
    18601 ccataaaatc aaaaatacat gtagaaatta tggctttaat cctaatatga tttttaaaac
    18661 cactcaatgg agcttcacag aagaaatatt attaaataat ctagggatat gtatattacc
    18721 cgaaggaata ctagacttat tagataataa tttacaagtc atcgatatta ataaaccttc
    18781 catgaaatgg gaacttacta ttatttggag aaaagatatt atagttgatt ctttaacaaa
    18841 aaattggatt aaatttctcc aagaaaaatt cttaattaac tattaaatat aaaagcattt
    18901 gagaaattta tagctatata aaaaaaggat attttatatt tatacactct cgctctataa
    18961 ttagaacgta aaacattata gaaacgggag ttttttatgg aaaattataa atttcctagt
    19021 gatagtaaaa ttgtcagtac ggaccaagta ttaattaatg atttaaacaa ttataataca
    19081 ctatttgggg gggtgttaat gaaaaaaatt gataataacg ccacactatc agctagaaga
    19141 catgcaagag ttaaagaatg tgttacagct tctacagatt cagtagaatt tttatatcca
    19201 atcacccaat ctgattcagt ttgtatagaa tcttatgtag tttatacagg agaaaaatct
    19261 atggaaatat tttgtaaagt catttcagaa gatatgatta ctgcagaaag aaaaattgct
    19321 gctgtagctt ttcttacttt tgtagctttg gatgaaaaga aaaaaccaat taaaataccc
    19381 aaaatctctc ctcagtccaa agaagaaaaa ttattattta tggatggcga agcaagagct
    19441 aaaatgcgaa aaattaaaag atcacaaact aaaaatataa ttgactctct tgatatcaat
    19501 aagccatggg aattggagta gtgataaaat gattaatgaa atggaagaat taaaccaaat
    19561 taagttagat ttgaaaaaac taagaaacga atttcctagt atgtatgaaa agttagaata
    19621 tatagctagt ttgacaagac aattaagtat ccattataaa tatttaggag cacttatgtt
    19681 ttcagataac cgtgaaaata ttcaaaatga gagaccaatt ttaataagag aatctgtttt
    19741 aaaattatat gaacaagaag tagcaaaagt taaaaaagat agtgattttg tgttttttaa
    19801 agatatgatg ttaaaattcc aaaatgtgga ctactcacaa atatttctta tcattttagg
    19861 tgctgaacct ggttttgtat ttaataatac aattattaaa taataagttc attaagaatg
    19921 cttagattaa caaattataa aaatttaaaa atcacttgac taaataaaac tatattttag
    19981 ctaataaaag agccactctg atttagattg gctcttttat tagcttttat aacttaacga
    20041 gaatttttgc ttgtgattta tcgtttacaa gttgtttaaa tcctgactcc acaatatcat
    20101 ctaactctat ctcatcagta acgacatctt taacttttaa attaccttcg ttaattaaat
    20161 ctattgtttg ttgaaatgta gtaggtgtat aagcaattgt cgaagtgagc tttacacctg
    20221 tatttgttaa ttgcattgga ttccattcaa taggatgacc aaatatagac actataacga
    20281 cagtacctct tgctttagta acgtctatag cagatttaag tgttggcgct acaccagcta
    20341 cctcaaatgc tacatcaacg ccattatcag tgtatttact aataatatca cttgggtttg
    20401 attcaccaga atttatcgta tgagtagcac ctactgattt agctttatta agtcgctctt
    20461 ccgataaatc gaaaacaaat attttgctag caccagctgc tttggctgct atagttgtta
    20521 ataaaccgat tggccctgct ccaaaaatag caacagtatc gccaaataga acttcgcctt
    20581 ctttaattgc ttgaactgca acagccgtcg gttctacaag ggcgccttct ttatcagaaa
    20641 cattatctgg taatttataa acattctctt ctggggcgtt tgtaaattct gcaaatccac
    20701 catcagaacc taagcctata aatgaataac catcataaag gtcaatattt tcttcttttt
    20761 cacgatttga aactgtagga ttaataacaa cacgatcgcc tttgttaaat tttgtaacct
    20821 tagaaccaat atcatctact acgcctgcaa attcgtggcc taatgtaacg ggcgcttttt
    20881 ggccaaggaa cgggtctggt ttgtctgttg aaataaatat agggccttct aagtattcat
    20941 gtagatctgt accacaaatg ccagcccaag acactttaac tttaacctca ttatcttgta
    21001 actctttaga ttttcgatct tcaactcgta catccttttg accataccaa actgctgctt
    21061 tcattgataa aacctccttg ttttagttaa tttaatagta tgccttttaa aaattacttt
    21121 caagtaaact aaccttttaa tatagtgttt ctaaattatt atatgattag agtgtaccct
    21181 aatcatgtaa aatattgaat tagtttacta tttcaacatt ttattacgaa tatcttgttt
    21241 atcattttca tttaattctg ctaaacaatg ataaagatac tcgaaatgta gcaataatat
    21301 tactgcattt tgttttgttc catactgatt atcataacca tgcataatag aatgtctatt
    21361 aatttcattc atcctttttt caccaaattc aaaatttcgt tttaatttaa atttataata
    21421 ttctttgatt ttgacgtaat cagcatcaac ataataatca tgcttagatt tgtacttgtt
    21481 tatcgtttcc tcaattacaa tattaaagag tcgataatta gttcttcctt tataattcac
    21541 tgaattgaat atcatacctt ctaatcttgc taataatgca ggtattataa gataataata
    21601 ttcatgctta tatccatcta aaatctcttt taatatagta atatcttctt gaggtagttt
    21661 gtaagtggtt acttggcttt ttaaatgatt aaaatgaatt tcatcaaaat accttgtcat
    21721 tatcaaatta atattttctt tagttacctc ctgatgattt gaattcattt caacataatt
    21781 aataacttca tttatatcta cataatctat tggcggataa tcatagttaa taaaaattga
    21841 atttactgta gttgtattat caataaaact atctaaagca tctttaaatt catctaagtt
    21901 aggtatactt ttagctaaaa cttctattga ttcagatatt ttcttactgt atttagaatt
    21961 tatatctttt attgcttcgg atattttctt gctaaatata gaatttatat cttctatatt
    22021 tttatgcatt ctattaaaat ttaatttatc tagtatgata tgtttactaa aattattctt
    22081 cattttaatt tcccttctta atttacataa tgaccgttat cgttaacttt tttattttaa
    22141 attattgttt atcaatattt ataaaagcta tagaatcagt atttataaat aagaaatcgc
    22201 cgccatccgg aatttttata gaaatgctat ttgttttatc tttgactact ccttctatat
    22261 cttcaatgag cctattataa gcattttcac ctaatacact ttttataatc gcatattgct
    22321 ggtcactata atttaacacc tattgttatt ctttcttctt catatgtact cacagcttac
    22381 ctacctccaa ttttggattt ttttaatata gtatactctt ctgctaattt aatcactttg
    22441 cattcctacc aattatgatg ttataatgca cttaacaaag ttattaagca taatacacca
    22501 atcccctcac tatcggaagt agtgagggga ttttttaggt gttggctaaa ggtcgcctat
    22561 tttttcttat cgttgcgatt gcgtagccaa tgcgcaaata acgctacgat acaaccactc
    22621 gctgccgtgg tcgtgatgtg aacaaagtta tcaagcataa ttacacctcc tctctacgtc
    22681 aacttgacgc ctgagagata ggcgactcta taattatatc atctgtaaac atgtaagcat
    22741 atatacttcc gataagttga actatgttaa ttaaaactcc aaactaataa tacaaattgc
    22801 taatataaaa agtttgaaaa tcataattat aatttaatat ttaattacaa atctcgtttt
    22861 tagatttgaa aatttcgaat taagttattt aaaattaacg ttaataaaaa atatcaagat
    22921 tgaaaagata caaaaaattg ctataaaaag gaatcttttg ggattcctcc gggattctaa
    22981 agattcccat cccctataaa tacctttaca acagctttta tagaaaatcg tgaacagttt
    23041 cataatgcca gttaatgaca ctttactttt tcgatttatt tttgtcctta atttactata
    23101 agtgttgtca tagtagtatt tatggaactt aaaattaagt attcaaaacc ctagctatgc
    23161 taggtgccat gtaaatggca ttgttcaccc ttatcctgtt gtctaggaat cccaaaagat
    23221 tcccctacac tttaatggtt cataaacata agttagtttg tacctttaag ttctatttta
    23281 ttaagttatt tatgtcactg aaatcaaaat aagtgtatgc aaatatgaca ctaatcaaaa
    23341 atattaaagg gagtttaaaa caataatata taagcaacca aaatgatggt tgctataatt
    23401 acttagtgct aaaattctta atttctttat aaaaatggat tcccatattt ctcacaataa
    23461 ttataaaaac catgcctgtt tataaacatc gttttttcaa tattttcagg agcgtcaaat
    23521 tcaattagtt ttaaaactaa ttcagtaaat tcaagtggag ctgtaccatt tgcagtaact
    23581 gttttcccat ctttcactgc ttgcttttct ataaatttat tcgccgatgt ataacaatca
    23641 taatcactcc ataaacaaat agaatttcca gtgtgtttat aattattcaa aaatccattt
    23701 tttgctaggt aatcaacagc accacatata gcgcctactg gaatcccttt attaaaagtt
    23761 tcttggacaa atcttaaaag gtcatcacta ctgttatccc aagaattacc accaatcatt
    23821 atcaaaagat cataatcttt aggttcagaa ccaataacgt aatcaaccaa aactgaaaaa
    23881 ccgcctaaag aaacaacttt ttcttcaact gaaatagttt taactgacca agattcgctc
    23941 tggtttaaag tcgaagataa ataagaacct tcccaatctg caaactcatc taacaaaaga
    24001 aataaagcat ttttcataat aaaactcctt tttatttaaa cttttgaatt gttgttttat
    24061 taaatccaat tgcatattca agaccctttt cgacagttcg attcatacta atatgagcta
    24121 accaaatcaa tccaatttct aataaaaaag cttaaagata ttttaaaatt actccacttg
    24181 ggataataaa ttcttatgtt ttcctttata ctttattgaa attattaaag aaaaaattcc
    24241 aaataaacat atatgtaatc cactcgttga ttgatgcaaa taatactatt ttcttgtttt
    24301 tactatgttg cacaatgtgt gcaacaacac catatatagg tacaacatga tgtgcaacaa
    24361 cactatatat tggtgcaaca acctgtgcaa caaagaaaaa aagtgatggc actgggttaa
    24421 tctttaaacc cttgatatgt ctggcttcgc cagacccacc acaaaaagtg gtggcatata
    24481 tcccttatgc tctttactcg tgtgcaacag cctgtgcaac ataatatccc tcatacttac
    24541 tttcgaatta attttgcatc ataaatttct attgattata tagtcttttt tggactaaat
    24601 aatcaataaa agataatagt tttactaatt aaaaagacaa agtcttttta attttcgttt
    24661 tatagatttg actattttca attacttttt agcattatcc tctaaaatat tcacagatat
    24721 tttagctact atatcgatac atattactaa tccaataaag tgaaaaacca ataaagtgaa
    24781 agcaattatt tgaggtctat taaaattttt aaaagtaaaa ttaagtgtta ataatacaat
    24841 attcaataaa attatcagtg tagatattat tattaagcga ggtatctttt ttgataaaag
    24901 taacttaagg cgtttaaaat catctttata atatgtacag ttaatttccg taaataattt
    24961 tccttatttt tgggaatcaa cagtgtattt tgtgttgtta agttggtcgt agtagccccc
    25021 aacgtttccc aaatttgtaa aatctaatcc caaaacttaa acaaaaaata gacccaatct
    25081 aaataagatt aggtcttcac tttaatatct ttgagttatt tctatatagt atcaagacaa
    25141 gaaaaaacaa aaaatcatct aaatttagaa cgaaattcat caatagtatc atttactaaa
    25201 gtaatatgat ttttaagtaa ttttttttta tatttacact ttggacattt gtatttataa
    25261 cgcccaaaat aagttctagt aactttcatc tctctcttat catcaggaca atacggtccc
    25321 ttaacatcac atatttcaac ttcttccaaa tcttcaaatt tacatttttg taaatcaaga
    25381 ttcttccaat tttcggaaag aaaattaaaa agaacagtcc aagtaaagcc caaataatca
    25441 gtttttacaa accatttatt atatgaagcc ataactattc taggtatatc atcctgcaat
    25501 ctatctatgt atttttttat aaaaaaacgt attactaaaa caaacaaaaa taatacaaac
    25561 caataaaagt aaaatttata tttgattaaa aaatcaaaac ttatagattt caaactaaaa
    25621 aaatatactg aaaaattaat gattaacgta actaaaaatg aaataaataa atcatataaa
    25681 aaaaccttaa acttcgaatt cataaaaacc tccttaactc ttattttact acaatctata
    25741 caaccttttt agttttctct taagaaaaaa ctttattcca attgctttat tgacgttgag
    25801 cctcggaacc cttaacaatc ccaaaacttg tcgaatggtc ggcttaatag ctcacgctat
    25861 gccgacattc gtctgcaagt ttagttaagg gttcttctca acataaatgc gggttctact
    25921 ttttattttt actgacctta atagcaaaaa aagccatacc aatacaaaac cacataccta
    25981 taattgacaa ccacatagca gtcataaaac cactcctttt caccaaactt catcacaaga
    26041 cttattaaat tattaaatgc ctttatttcg aattttaagg ggttatttta aagatctagg
    26101 tataacccct atgcttttat acctaaaagc atacataagc tcttaaaacg caaatatgag
    26161 caaaataaat atgttttaat ttcacaaaca ttttttggtc taaaccagtg gcaaattttt
    26221 tagacattgc ccagttacat gcaaatctaa aaattaacat gaaaattggg caaccatgcc
    26281 ggttgaacgc tatagttccc gcaggggcaa aaagacatca aaaaacgttg ctttttaagc
    26341 tagggtttat caaaaaacgc ttttaaaaaa tcgaattatt aacttgaaaa tattaggaat
    26401 aaatacaaat atctgaaata caatgtctga aataatctca ataaaagctg acttagttct
    26461 cttgtatttt gtactcataa atcaaactcc taaccttttt taagtaatga ttttgctttt
    26521 taaaaatttc aaatttcaat aactaaatgt gcttctcttt cttcctcact tgtataaaca
    26581 ttaacgctta gtattcactt ctcaaaagac catagatcaa tgtgtctcta tattcatctt
    26641 gcactaattt atcttttctc aacatgccct ctcgtttcat acctaacttt tccaacacaa
    26701 ttccggaagc tatattgttt gaatcaatgg ctgcccctat tctattgagt ttcagtactt
    26761 taaaggcata tttgatgatt gttttcgcga tatccgtcgc aacgccgtcg ccccaataat
    26821 ttggatggac aataaagtta atttcagcac tttggttcac ttcatctatg gctaattgta
    26881 tcgcccctat gactttatct gtatcaggat caacgaggac attgtaaatc caattggatt
    26941 ctttatctaa caccacatta atgaactgct gagtctcttc ataactttga ggaccccaag
    27001 tttgatactg agtcacttct ggtaaagcat ataattcatt taaatatcta tatctgtgtg
    27061 ctttaagtct ctagaataga acgccatacg cgccctccta aaatagtttg ctcctatgta
    27121 accctttatt tactagctac atataatata aagggtgttc tcttaattta aatgtgaaag
    27181 cacgccacat ctactgatta aagatattat gttgtttcat gttttgacgt cgcatataaa
    27241 gtgcatgtgt ttcttcgaat tcagctttaa tagattgcat taaataccct tgcatcgctt
    27301 caacggtttc attcttttgt agcagcatcg ctttaaaacg tttcaacaca cttacaattt
    27361 caaactcaac atcttctaaa cggtaatacg tatcatgtgc attattaaat gattttttac
    27421 ctttgagtaa tacactttta ataatccgaa tttctctaat ttcaaattta cttaaatagt
    27481 cttgaagttg ttgaggcaat tcttcgagga cttggaactt aagcgcatca ttattaaatt
    27541 cggtttgttg atgatttgta tgatccgaat gattattgtt tattggattg ttgtatgtat
    27601 cattcaagtc attcgtatca ttattctcag tctctatata atcagtatta cttaagtcag
    27661 tatcattaga gtctaagttt tgggattctg ggctcccatt gtttgggatt ctgggctccc
    27721 attgtttggg attctggact cccattattt gggattcctt gctatcactt gattcgtcat
    27781 tgtttgaagt gctattttgt atttcttttt caatatttat atttgtttca atttcatgaa
    27841 ggtatagttt gtttggtcga ttaaatccag ttttaacttg ttctaataaa cccacttctt
    27901 gtaattcttt tttaattttg gttattgtat ttttactttt atctaacact tcttgaagat
    27961 tttcatttgt gaaaataaaa tatatatctc cattttgatc tatccaatta tttttaatag
    28021 ataaacttac tctatcatta agaattgcat aggtaacttt tgcactatca cttaactttt
    28081 tatatttttc attgataaat aatactttat gtagcatata gaaattttga ctggcctgat
    28141 tttttatgtt ttttctagac ataataaaaa cccctttcct attcaaattt tggatagagg
    28201 taataaaaca ttacaagaac acataaattt tttgcttgca ctttgatgat atagttgtat
    28261 ataatacaga tatcaaaata tttataaacg tgctgcaacg ttttattacc aaaccccgac
    28321 tattaccagt agttggggtt tttgttgtat taaggttatt atagcacttt gaataagctt
    28381 ataaaaggga aaatgtagtg ttgtcaaggg ttgataaagg gtttgcaaac ccttgacaac
    28441 taccgtcaac cctttacaaa tacttgataa aagggttgac ggttttatat tttcgactta
    28501 tcaatcactt tattattaag cgtgataagc ttataatatg ttataaaggg ttg
//
