LOCUS       NZ_CP067388             9581 bp    DNA     circular CON 31-MAR-2024
DEFINITION  Klebsiella grimontii strain 5512.56 plasmid p5512.56-4, complete
            sequence.
ACCESSION   NZ_CP067388
VERSION     NZ_CP067388.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN17215154
            Assembly: GCF_017863935.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella grimontii
  ORGANISM  Klebsiella grimontii
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 9581)
  AUTHORS   Campos-Madueno,E.I., Moser,A.I., Risch,M., Bodmer,T. and
            Endimiani,A.
  TITLE     Exploring the Global Spread of Klebsiella grimontii Isolates
            Possessing blaVIM-1 and mcr-9
  JOURNAL   Antimicrob Agents Chemother 65 (9), e0072421 (2021)
   PUBMED   34181480
REFERENCE   2  (bases 1 to 9581)
  AUTHORS   Campos-Madueno,E.I. and Endimiani,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JAN-2021) Institute for Infectious Diseases,
            University of Bern, Friedbuehlstrasse 51, Bern 3001, Switzerland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 262.28x
            Sequencing Technology :: Illumina NovaSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_017863935.1-RS_2024_03_31
            Annotation Date                   :: 03/31/2024 06:04:30
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,919
            CDSs (total)                      :: 5,803
            Genes (coding)                    :: 5,650
            CDSs (with protein)               :: 5,650
            Genes (RNA)                       :: 116
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 84
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 153
            CDSs (without protein)            :: 153
            Pseudo Genes (ambiguous residues) :: 0 of 153
            Pseudo Genes (frameshifted)       :: 71 of 153
            Pseudo Genes (incomplete)         :: 96 of 153
            Pseudo Genes (internal stop)      :: 26 of 153
            Pseudo Genes (multiple problems)  :: 34 of 153
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP067388.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..9581
                     /organism="Klebsiella grimontii"
                     /mol_type="genomic DNA"
                     /strain="5512.56"
                     /isolation_source="Not defined"
                     /host="Homo sapiens"
                     /db_xref="taxon:2058152"
                     /plasmid="p5512.56-4"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.38824 N 8.34350 E"
                     /collection_date="2014-09"
                     /collected_by="Institute for Infectious Diseases,
                     University of Bern, Friedbuehlstrasse 51, 3001 Bern,
                     Switzerland"
     gene            complement(206..1033)
                     /locus_tag="JJJ11_RS00610"
                     /old_locus_tag="JJJ11_00610"
     CDS             complement(206..1033)
                     /locus_tag="JJJ11_RS00610"
                     /old_locus_tag="JJJ11_00610"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004198917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family A protein"
                     /protein_id="WP_074177990.1"
                     /translation="MISVNLTTMHSRLDLCAATVWSIINQSVQPDKINLWISNEPYLSD
                     HGIYEIPAWVEELNKINNIVNVHYVKNTGPYRKIINAIINSEIDDILVYADDDVIYGRQ
                     WLEFLLDQFYENNCNVAIAARIRIMERNIFNKYKSYSSYSISMKKDKFEKDFIITGVGG
                     CVLSKRMIKPSIIGDDAYLTISPKTDDIWISKMLEASNTKVESSPDALRCVHEILHGYN
                     TLSSINTLTSKNSSLIIKAIRMVKNKFYSYFGLQKTNNDKSIKMVNLHFNGKL"
                     /name="glycosyltransferase family A protein"
     gene            1215..1913
                     /locus_tag="JJJ11_RS00615"
                     /old_locus_tag="JJJ11_00615"
                     /pseudo=""
     CDS             1215..1913
                     /locus_tag="JJJ11_RS00615"
                     /old_locus_tag="JJJ11_00615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /name="IS1 family transposase"
     gene            complement(2288..2401)
                     /locus_tag="JJJ11_RS00620"
                     /old_locus_tag="JJJ11_00620"
     CDS             complement(2288..2401)
                     /locus_tag="JJJ11_RS00620"
                     /old_locus_tag="JJJ11_00620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032634168.1"
                     /translation="MHEPPVQSDCCALSGNYRLESNPERHAKAPLAAATGN"
                     /name="hypothetical protein"
     gene            2973..3122
                     /locus_tag="JJJ11_RS00625"
                     /old_locus_tag="JJJ11_00625"
     CDS             2973..3122
                     /locus_tag="JJJ11_RS00625"
                     /old_locus_tag="JJJ11_00625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017880354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_015062850.1"
                     /translation="MPSEHDEQWDAADTQLPGEYDLFDLMAQVTEENLHAPVDSGPPVG
                     REAL"
                     /name="hypothetical protein"
     gene            3603..3794
                     /locus_tag="JJJ11_RS00630"
                     /old_locus_tag="JJJ11_00630"
     CDS             3603..3794
                     /locus_tag="JJJ11_RS00630"
                     /old_locus_tag="JJJ11_00630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_004187666.1"
                     /translation="MTKQQKTALNMAKFIQNQSLLLLEKLNELDLDVEADLCEKLHDDA
                     EHLFRTLSSRLDALQDGN"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            3794..4216
                     /locus_tag="JJJ11_RS00635"
                     /old_locus_tag="JJJ11_00635"
     CDS             3794..4216
                     /locus_tag="JJJ11_RS00635"
                     /old_locus_tag="JJJ11_00635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_015062851.1"
                     /translation="MARVSISEAAQLVKVSRPTIYKMINSGKLSYTSVVKHGKSIKVID
                     TSELIRVFGSLDGVIDTVKYDVKSDSESTGINSVVLHDLQHRIALLEAENDGLKGAVKA
                     RDEHIDSLRQAMQLLEHKHEPSSPPYSPWWKFWKKS"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(5320..6427)
                     /locus_tag="JJJ11_RS00645"
                     /old_locus_tag="JJJ11_00645"
                     /pseudo=""
     CDS             complement(5320..6427)
                     /locus_tag="JJJ11_RS00645"
                     /old_locus_tag="JJJ11_00645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611476.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /name="IS3 family transposase"
     gene            complement(<6501..6886)
                     /locus_tag="JJJ11_RS00650"
                     /old_locus_tag="JJJ11_00650"
                     /pseudo=""
     CDS             complement(<6501..6886)
                     /locus_tag="JJJ11_RS00650"
                     /old_locus_tag="JJJ11_00650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558267.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /name="IS1 family transposase"
     gene            complement(7108..8043)
                     /locus_tag="JJJ11_RS00655"
                     /old_locus_tag="JJJ11_00655"
     CDS             complement(7108..8043)
                     /locus_tag="JJJ11_RS00655"
                     /old_locus_tag="JJJ11_00655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004198895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_224354408.1"
                     /translation="MMLLSIIIPCYNCESNIEKLLLSIKEQLNETVQLVLINDGSWDAT
                     HDIITKFTSDNPSIKIKYINSINQGAAKARSTGLNYAEGDYVFFCDSDDMISANFISVF
                     TELSNDKPDMIYFCSTVLDSQGNRFKKVHFPLAYIESNSNEVFNYLLKKGQWTAAVWTY
                     IFRKDLVLKSGAIFTDRKVHEDHLFTLRLLAGSEKISICNSELYFQNVTSGSLTKSPKK
                     IDYLTERYKSYKEAREDIIYKFSQESIVLYDRWSMSSLLQILKENKKMVFQGIMHTAIY
                     RVLWKEKLVILDFVKSKVKKKITRSKSLSQ"
                     /name="glycosyltransferase family 2 protein"
     gene            complement(8040..9506)
                     /locus_tag="JJJ11_RS00660"
                     /old_locus_tag="JJJ11_00660"
     CDS             complement(8040..9506)
                     /locus_tag="JJJ11_RS00660"
                     /old_locus_tag="JJJ11_00660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017803471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MOP flippase family protein"
                     /protein_id="WP_167876629.1"
                     /translation="MNLKSKTIHAVKWNLLSTVCVTGLGMVSLWILSSLFTTTDYGIIS
                     AALILSTVFSIITDFGISNSVIRSEKLNKYELSSLYIINVFLGMIFCLGLFIFSAQLAS
                     LFNGGTELAKQIKIMSFSLIISSFGGQPRALLARGLRFDVISRITILSAIFNFVFAVFL
                     SYVYRSPWCVAVSLLVSSSISSVLYIYSSKGLRDIKLQFFTLKEIKKHVSYGSQLVMDS
                     IINQISVNTYPVLMARLISLTAIGGYNISYNISVALFEKLNPVLSHALFPAFSKIQNDA
                     ASLKKTFLKVTMFSSLVNFPMLLGMMLISDYVVTVFFEQKWQFITPIVQILCLVGAARS
                     LDVPVISVLLAKGQMYRNVYLGVFKLALGIPLTWFLGKQYGLTGIVFSFLCIQIVNLVM
                     GYFFQVRPCLNIKVKSYIYAVFVPLIHTLPMLVTGYLLILFLTITSPILSMVVIIFSCM
                     SVYIASILTSPVKEIKEFNAIVLNNILRNK"
                     /name="MOP flippase family protein"
     Typing          2766..2980
                     /name="MOB_unknown"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.364"
                     /coverage="100.0"
                     /evalue="3.53e-41"
     Typing          complement(2293..2841)
                     /name="rep_cluster_2335"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.948"
                     /coverage="90.0"
                     /evalue="0.0"
ORIGIN
        1 tatcccaaag taatgctgcc aacctgttgg tgaccatttg aatctgtagc cattcaaccc
       61 ttgtaatatc aggtgatcct ggcgtcagtg aaaatgcgaa atcaataaat tggcatcatt
      121 acccaaaaag caataacaat ttgctaacca ctacagttta ctgataacat tttgttttca
      181 gacaatccct gatgagaaag atcatttata atttaccatt aaaatgcaaa ttaaccatct
      241 tgatggattt gtcattgttt gttttttgca acccaaaata tgaatagaat ttgtttttaa
      301 ccatcctgat tgcctttata attaaactgc tatttttaga tgttaatgta tttattgagc
      361 taagtgtgtt atagccatgc aatatttcat gaacacatcg cagtgcatct ggggatgact
      421 cgaccttcgt attagaagcc tctaacattt tactaatcca gatatcatct gtcttaggtg
      481 aaatagttaa atatgcatca tctccgataa tgctaggctt aatcattctc ttacttaaaa
      541 cacaaccccc aacgccagtt attataaaat ccttttcaaa tttatccttt ttcatactaa
      601 tagaataaga gctataagat ttgtacttgt taaaaatatt cctctccatt attctaatcc
      661 tagcagcaat tgccacatta cagttgttct cataaaactg gtctaatagg aactcaagcc
      721 actgccgacc atatattaca tcatcatcag catatacaag aatgtcatca atctctgagt
      781 taataattgc gttaattatt ttacggtatg ggccggtatt ttttacataa tgtacattca
      841 ctatgttatt tattttattt agctcttcaa cccaagcagg tatctcatat atcccatgat
      901 ctgacaaata tggctcattt gatatccaaa ggtttatttt atctggctga acactctggt
      961 ttataattga ccacactgtg gcggcacata aatccagtcg agaatgcatt gtagttaaat
     1021 taactgatat catgctaccc tttaaagaaa aaattaattt aatgttatat tatatgtaaa
     1081 aaggttacat attcaatatg taggacgttt tttcgaaaaa atcagttttt ttcctgatga
     1141 accttcctcc gcgttgcccg gtaatgctgc caacttactg atttagtgta tgatggtgat
     1201 tttaaggtgc ttgcgtggct tccatttcca tcagatgccc ttcctgctcc gctactgaag
     1261 gcgtggtgcg taacggcaaa agcactgccg gacatcagcg ctatctctgc tctcactgcc
     1321 ataaaacatg gcagctacag ttcacttaca ccgcctctca gcccggtacg caccagaaaa
     1381 tcattgatat ggccatgaat ggcgttggat gccgggcaac cgcccgcatt atgggcgctg
     1441 gcctcaacac gattttacgt cacttaaaaa actcagtccg cagtcggtaa cctcgcgcat
     1501 acatccgggc agtgacgtca tcgtctgcac ggaaatggac gaacagtggg gctacgtcgg
     1561 tgctaaatca cgtcagcgct ggctgtttta cgcgtatgac aggatacgga ggacggttgt
     1621 ggcgcatgtc ttcggtgaac gcactctggc cacactggag cgtcttctga gcctgctgtc
     1681 accctttgac gtggtgatat ggatgacgga tggctggccg ctgtatgaat cacgcctgaa
     1741 gggaaagctg ccacgttatc agcaagcgtt atactcagcg cattgagcga cataacctga
     1801 atctgagaca acatctggca aggctgggac ggaagtcact gtcgttctca aaatcggtgg
     1861 agctgcatga caaggtcatc gggcattatc tgagcataaa acactatcag taagttggag
     1921 tcattaccgg gatatcgttc accacgggaa tacctgcggc ggcgaaccag taatgggtta
     1981 agtgataaaa agtgtatgga aatatagggg ccaatccagc tcttcagtca atgatggttt
     2041 tgatgagcct gaacattgat atcgtcgtag atcttgaaag gatcttcttg agatccgttt
     2101 ttgaacgtcg taatctcttg ctctgtaaac gaaaaaaccg cctttgcggg gcggtttttc
     2161 cgaaggttcg tagagtttgc ggctctttga accaaggtaa ctggctagtt agaggagcgc
     2221 agtcaccaaa actgttcgtt tagtttagcc ttaaccggcg cataacttca agactatctc
     2281 ctctaaatca gttaccagtg gctgctgcca gtggcgcttt tgcatgtctt tccgggttgg
     2341 actcaagacg atagttaccg gataaggcgc agcagtcgga ctgaacgggg ggttcgtgca
     2401 tacagtccag cttggagcga actgcctacc cggaactgag tgtcaggcgt ggaatgagat
     2461 aaacgcggcc ataacagcgg aatgacaccg gtaaaccgaa aggcaggaac aggagagcgc
     2521 acgagggagc caccaggggg aaacgtctgg tatctttaag tcctgtcggg tttcgccacc
     2581 actgatttga gcgtcagatt tcgtgatgct tgtcaggggg gcggagccta tggaaaaacg
     2641 gcttcgccgc gaccttatcg cttccctgtt aagcttctcc ctggcatcta ctaccaggaa
     2701 gtttccgtcc cgcccgtaag ccggtaccgc tcgccgcagc cgaacgaccg agcgcagcga
     2761 gtcagtgagc gaggaagcgg aatatcttct gtatcgcata ttctgcttac gctctgctgc
     2821 agcatttttc tcctgccaca tgaggcgctt tcctgattat cgcactcatg ccaacataat
     2881 aagccattat acactctgct agcgctacgt gactggttca gggttgcgcc ccgaaacccg
     2941 ctaacaacct ctcagctact ggatatcatc ccatgccatc tgaacatgat gaacaatggg
     3001 atgctgctga tacgcagctt cccggcgaat atgacctttt tgatttaatg gcgcaggtta
     3061 ctgaagagaa cctgcatgcc cctgtggatt ccgggccacc tgtcggccgg gaagcgttat
     3121 agctttttcg cttgcccgcg tacgtggtaa tacgccggta ttacatttta tttctttatt
     3181 ttcatgtgat tacaggtgat tgtaatacgt tgcgtattac ataaataagc tggaatttca
     3241 gtttttacct tttaattcat gcagttgcga tgaaaatcgc ggctgcgtta ggtgtatgac
     3301 catttaaggg gcaaaaaatt atcattctgg ccgggtgtac tgcgcaggtt aaggagcatc
     3361 ggtgacgaaa aagcgtcctt agcgacctcg ttcatgctcg catgaacgga ttatttttcc
     3421 ggactacagg taaactacag aaagactaca aaagctgatg acttaatcct gatttttagt
     3481 gcgatgacta cagataaact acaaaataac tacaggatta cctcagattc gttctctgaa
     3541 ccattcgtac atccgacccc cttaccggtt ttacactgag cactgatgct ctgaggtccc
     3601 ttatgacgaa acaacagaaa acagcgctga acatggctaa attcatccag aatcagtctc
     3661 tgctcctgct ggagaagctt aacgagcttg atctcgatgt cgaggccgac ctttgtgaga
     3721 aactccacga tgatgcggag catcttttcc gtactctgtc ctctagactg gatgcattac
     3781 aggatggtaa ctgatggcca gagtgtctat tagtgaagcg gcacagcttg ttaaggttag
     3841 tcgccccacg atttacaaga tgattaacag tgggaagtta agttacacct ctgttgtaaa
     3901 gcacgggaag tctattaaag ttattgatac ttcagagctt attagggtgt ttggttctct
     3961 tgatggtgta atcgatactg taaaatatga tgtaaaaagt gactcagaat ctacaggtat
     4021 taacagcgtt gttttacatg atttacaaca tagaatcgct ttacttgaag ctgaaaacga
     4081 tggtcttaaa ggggctgtta aggctcgaga tgagcatatt gattcccttc gtcaggctat
     4141 gcagcttctg gaacacaagc acgaaccttc ttcaccaccc tattccccgt ggtggaaatt
     4201 ctggaaaaaa tcctgatccc gccatgcttc agttttcctc tccggtcatc ccggggcgtt
     4261 cctgaacctt cccagatacc gccagatctc tgaacgctcc tcaccactaa aaatacccat
     4321 acccacaccc cacgcaaaat taaaattttg aagataactc attaatatca gttagttagt
     4381 tgttactaaa ttacgcagta ttaccttctg taaggtcaat ccaagtcgtc ggcgattcgt
     4441 gtacgacttg ccgacgactc gtcatagagt catcgacgat tcactccaca ctatcagtaa
     4501 cttatgacga cttgactcta gagtcgaatc gtcattttgg tgtttttttg accttgacga
     4561 ctctagagtc aagtcacgag tcgaatcgcc ggtgaatcgt gtggtgagtc gtccggcgac
     4621 ttgccataac gtgattgccg gccgtcgacg aacccgattc ctgaacgtgc tgaaaatcgg
     4681 ttttccggct gcgccggcaa cgcttcatgg ccacgcaata aattgcgtcc ccgttcaccg
     4741 ttttcggatg ggaagaacgc cggaaacagg acttaccccg gctgaatggc gtgaatttcc
     4801 gcgctatgca cttgcgtgca tactcatgca tgccgtaaaa acagagccag cgcgtttctg
     4861 gcggattttc ggggggggtg ttgcctgttt taccggtttc ctgccagaaa cgccctgagg
     4921 ccgttttcgc ggtgcgcgta agaagggatt atggtaaata gggcgctatc gcctaaatac
     4981 acggctgatt gttttttttc tctgaagtat gagattcctg agtagacagc tacaacaagt
     5041 agcgcaatgg cgatagcaag tgaaatccag tccataaatg cctgattaat ttaataaaaa
     5101 cagcctgtta tgatttcata aagataatat catctttttt ttagcatgat actgtcgtta
     5161 cttattgtgg tgagatgaaa cataaccgct gtttttgtat gtgtttgtta aggctgctaa
     5221 gattattcct aaccactgat tttgtacata tcatcaaaaa aataaaaaaa ctaatgccct
     5281 gtggtgggta tgacctgccc ccaggattag atacaacctt cagttagtaa tgtcggttcg
     5341 tttttcttca tatttcccgt ttcgccagcc cgccgcaaat tcagccggag tctggtagtt
     5401 cagcgatgaa tgtggacgac actcgctcta atcctgccgc cagtcattaa tcgttttcct
     5461 cgcgtgaacg atatcgcgga accagtgctc attgaggcac tcatccctga atcgtccgtt
     5521 aaaactttca ataaatccgt tctgtgttgg cctgcccggc tggataagcc gcagctccac
     5581 cccatgctca taagcccact ggtcgagtgc tctgcaggta aactccgccc cctggtcagt
     5641 tcttatcgtc gccggatagc cgcgaaacag tgcaatgctg tccagcattc gcgtgacctg
     5701 aacgcctgaa atcccaaagg cggcggtaat tgtcagacac tccttcgtga agtcgtccac
     5761 gcaggtcagg cacttgatcc tgcgaccggt ggccagcgcg tccatgacaa aatccatcgg
     5821 ccaggtcagg ttgggcgcct ccgggcggag cagcggcaga cgttctgttg ccagaccttt
     5881 acgacgtcgt ctgcgtttta cacccagccc gttaagatgg taaagacggt acacgcgctt
     5941 gtgattaaca tgaaggcctt cacggcgcag taactgccag atgcgtcggt agccaaaacg
     6001 cctgcgctcc agtgccagct cagtgatgtg ccctgataaa tgcgcatcag ccgcgggacg
     6061 ctgagcctca tagcggcagg tcgacaggga caaacctgta agcctgcagg cacgacgttg
     6121 cgacagaccg gtcgcatcac acataaactc aacggcttcc gtttctggtc tgtcgtcagt
     6181 actttcgccc cagagccacc tgaagtgcct ccttatccag catggcttcg gcaagcagtt
     6241 tcttgagtct ggcgttctct tcctcaagcg acttaaggcg cttaacctcg ggcacctcca
     6301 taccgccata catcttacgc caggtgtaaa agatggcgtc ggaaatggcg tgcttacggg
     6361 cagaaacccc ggcttcggcc tcgcggagaa tactgatgat ctgttcgtcg gaaaaacgct
     6421 tcttcatgag gatgtcctca tgtggcttat gaagacatta ctaacatcac ggtgtattaa
     6481 ccaacgggga gcaggtcact gtcatacgcg taaaacagcc agcgctgacg tgatttagca
     6541 ccgacgtagc cccactgttc gtccatttcc gtgcagacga tgacgtcact gccaggatgt
     6601 atgcgcgagg ttaccgactg cggactgagt tttttaagtg acgtaaaatc gtgttgaggc
     6661 cagcgcccat aatgcgggcg ctggcccggc atccaacgcc attcatggcc atatcaatga
     6721 ttttctggtg cgtaccgggc tgagaggcgg tgtaagtgaa ctgtagctgc catgttttac
     6781 ggcagtgaga gcagagatag cgctgatgtc cggcagtgct tttgccgtta cgcaccaccc
     6841 cgtcagtagc tgaacaggag ggacagctga tagaaacaga agccacgcaa gcaccttaaa
     6901 aacaccatca tacactaaat cagtaagttg gcagcatcac ccagaaagac cataaaatta
     6961 gcctataacg gcaaatagta atgctgccaa cctgttggtg accatttgaa tctgtagcca
     7021 ttcaatcctt gtaacatcag gtgatcctgg cgtcagtgaa aatgcgaaat caacaaattg
     7081 gcatcattac ccattatacg ataatcccta ttgggatagg ctcttagatc tcgtgatttt
     7141 ttttttaact ttgcttttaa caaaatctaa aatcactaat ttttccttcc acaatactcg
     7201 atatatagct gtatgcatta tcccctgaaa caccattttt ttattttctt ttaatatttg
     7261 cagtagcgaa gacatagacc atcgatcata aagaacaatg ctttcctgac tgaatttgta
     7321 aatgatatct tccctggcct ctttataaga cttataacgc tcagttaaat aatcaatttt
     7381 tttaggggat ttagtaagtg aacctgaagt cacattctga aagtaaagct cagaattaca
     7441 tattgatatt ttttcactac cagcgagaag tctcagcgtg aataagtgat cttcatgtac
     7501 ctttctgtct gtaaatatag cgccagattt caatacgaga tctttccgga aaatataagt
     7561 ccatacagca gctgtccact gccctttctt caaaagataa ttaaaaactt cgttactatt
     7621 gctttcgatg tatgctaatg gaaaatgtac ctttttaaac ctgtttcctt gcgaatctaa
     7681 taccgtagag caaaaatata tcatatccgg tttatcatta cttaactctg taaaaaccga
     7741 tatgaaatta gcagaaatca tatcatctga atcacagaag aatacataat ctccctctgc
     7801 gtaatttaag cccgttgatc tggcttttgc cgccccctga ttaatactat taatgtattt
     7861 tatttttata gaggggttgt cacttgtaaa tttagttatt atgtcatgcg ttgcgtccca
     7921 tgagccatca ttaatcaaca ctagttgtac ggtttcatta agctgctctt ttattgagag
     7981 aagcaatttt tcgatatttg actcacagtt ataacatggt atgattattg ataataacat
     8041 catttattcc tcagtatatt gtttagaacg attgcgttaa attcctttat ctcttttact
     8101 ggagaggtga gtatagaagc aatgtataca gacatacatg aaaaaataat cacaaccatt
     8161 gacaaaatag gagaggtaat agttaaaaaa agaatcaaca ggtaacccgt tacaagcata
     8221 ggtaaagtgt gtataagcgg tacgaagacg gcatagatgt aactctttac tttgatattt
     8281 aaacagggtc taacctggaa aaaatatccc ataacaagat ttactatttg aatacataag
     8341 aatgaaaaca ctatccctgt aagaccatat tgtttaccca gaaaccatgt taaaggaata
     8401 ccaagcgcta acttaaatac tcccaggtaa acatttctgt acatttgccc tttagcaagc
     8461 aagacagaga taacaggcac atcaagggat cgcgccgccc caaccaaaca taaaatctgt
     8521 acaatagggg tgatgaactg ccatttctgc tcaaaaaaaa cagtcactac atagtctgaa
     8581 attaacatca ttcccaataa catcgggaaa ttcaccaaag acgaaaacat agttactttt
     8641 agaaaagttt ttttcagaga tgctgcatca ttttgtatct tggaaaaagc tggaaataac
     8701 gcatgtgata aaacaggatt caatttttca aaaagcgcca cgctaatgtt gtaggatata
     8761 ttatatccac cgatagcagt caaacttatt aagcgtgcca ttagtacagg atatgtattc
     8821 acgcttatct gattaatgat agagtccatg accaactgag aaccgtagct gacatgtttt
     8881 tttatttcct tcaaagtaaa gaactgtaac ttaatatctc tcaagccttt gcttgaatat
     8941 atatacaata cgctactaat agatgaggaa accaacagtg aaacggcaac acaccagggg
     9001 gaacgataga cgtagcttaa gaagactgcg aacacaaaat taaaaatagc tgacaggatt
     9061 gttatcctgg atattacatc aaatctaagt cctctggcta acaaagctct tggctgtcca
     9121 ccgaaagacg atattataag agaaaatgac atgattttta tctgttttgc cagttctgtt
     9181 ccaccattga ataaggatgc taactgagca ctaaaaataa acaagccgag acaaaatatc
     9241 atacctaaaa agacatttat tatatacagt gaagacagtt catatttatt taacttttca
     9301 gatcttataa ctgagtttga tataccaaaa tcagttatga ttgagaaaac agtacttaat
     9361 attaatgccg cactaatgat accataatct gtcgttgtaa ataagctgga caagatccac
     9421 agtgagacca taccaagccc ggttacgcac actgtagaca acaaattcca cttcacagca
     9481 tgtattgttt tcgattttaa attcatattt attgtcagtg atataaaata attacattgg
     9541 tgtactaaaa ggaatttttt atacctttca gcgttagagc c
//
