LOCUS       NZ_CP067238            25897 bp    DNA     circular CON 18-JUN-2023
DEFINITION  Escherichia coli strain SBF22 plasmid pSBF22c, complete sequence.
ACCESSION   NZ_CP067238
VERSION     NZ_CP067238.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN17214847
            Assembly: GCF_017638985.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 25897)
  AUTHORS   Biggel,M.
  TITLE     Characterization of fosA carrying plasmids from multidrug resistant
            Enterobacteriaceae food and environmental isolates
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 25897)
  AUTHORS   Biggel,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JAN-2021) Institute for Food Safety and Hygiene,
            University of Zurich, Winterthurerstrasse 272, Zurich 8057,
            Switzerland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology :: Illumina MiniSeq, Oxford Nanopore MinIon
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 06/18/2023 03:44:13
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,137
            CDSs (total)                      :: 5,018
            Genes (coding)                    :: 4,837
            CDSs (with protein)               :: 4,837
            Genes (RNA)                       :: 119
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 91
            ncRNAs                            :: 6
            Pseudo Genes (total)              :: 181
            CDSs (without protein)            :: 181
            Pseudo Genes (ambiguous residues) :: 0 of 181
            Pseudo Genes (frameshifted)       :: 64 of 181
            Pseudo Genes (incomplete)         :: 128 of 181
            Pseudo Genes (internal stop)      :: 28 of 181
            Pseudo Genes (multiple problems)  :: 34 of 181
            Pseudo Genes (short protein)      :: 4 of 181
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP067238.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..25897
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="SBF22"
                     /isolation_source="surface water"
                     /db_xref="taxon:562"
                     /plasmid="pSBF22c"
                     /geo_loc_name="Switzerland: Dietlikon"
                     /collection_date="2017"
                     /collected_by="ILS, University of Zurich"
     ARG             complement(2..906)
                     /name="floR"
                     /gene="floR"
                     /gene_name="major facilitator superfamily (MFS) antibiotic
                     efflux pump"
                     /tool="rgi"
                     /drug_class="phenicol antibiotic"
                     /identity="99.01"
                     /coverage="74.75"
     ARG             complement(25590..25897)
                     /name="floR"
                     /gene="floR"
                     /gene_name="major facilitator superfamily (MFS) antibiotic
                     efflux pump"
                     /tool="rgi"
                     /drug_class="phenicol antibiotic"
                     /identity="100.0"
                     /coverage="25.25"
     gene            complement(1123..2007)
                     /locus_tag="JJB19_RS25765"
     CDS             complement(1123..2007)
                     /locus_tag="JJB19_RS25765"
                     /inference="COORDINATES: protein motif:HMM:NF023271.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3363 domain-containing protein"
                     /protein_id="WP_001447541.1"
                     /translation="MLRSQRRGRDPPCWLSEKEPLVGKRRVNFQRCWLPVSRIGLHRRG
                     VERVNCGPKLLDLGEKGVYSSYTCRVPGGDYEGYVDAHVRRLEALRRAGIVERIDADQW
                     RIPDDLVSRAAAHDAGRDSQASVRVLSPVDLNKQIGSDGATWLDRRLIHGETADLAPTG
                     FGQQVREAMDQRREHHIEQGDATRSRDSRVFYRRNLLAILREREVAGVGSDMALSKGLP
                     FRAATDGESVSGKFTGTVHLSSGKFAVVEKSHEFTLVPWRPIIDRQLGREVMGIVQGGS
                     VSWQLGRQRGLER"
                     /name="DUF3363 domain-containing protein"
     gene            complement(2038..>2868)
                     /locus_tag="JJB19_RS25145"
                     /old_locus_tag="JJB19_25140"
                     /pseudo=""
     CDS             complement(2038..>2868)
                     /locus_tag="JJB19_RS25145"
                     /old_locus_tag="JJB19_25140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001120888.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS91-like element ISVsa3 family transposase"
                     /name="IS91-like element ISVsa3 family transposase"
     gene            2932..3636
                     /locus_tag="JJB19_RS25150"
                     /old_locus_tag="JJB19_25145"
     CDS             2932..3636
                     /locus_tag="JJB19_RS25150"
                     /old_locus_tag="JJB19_25145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067784.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1006 family transposase"
                     /protein_id="WP_001067784.1"
                     /translation="MNPFHGRHFQGEIILWAVRWYCKYGISYRELQEMLAERGVNVDHT
                     TIYRWVQRYAPEIEKRLRWYWRNPTDLSSWHIDETYVKVNGRWSYLYRAVDQRGDTIDF
                     YLSSRRNTKSAYCFLGKILNNVKKWQIPQVINTDKAPTYGRALSRLKREGKCPPDLEHR
                     QIKYKNNVIECDHGKLKRIIRATLGFKSMKTAYATIKGIEVMRALRKGQASSFYYGQPQ
                     GEVCLINRVFGL"
                     /name="IS6-like element IS1006 family transposase"
     gene            complement(3721..4197)
                     /locus_tag="JJB19_RS25155"
                     /old_locus_tag="JJB19_25150"
     CDS             complement(3721..4197)
                     /locus_tag="JJB19_RS25155"
                     /old_locus_tag="JJB19_25150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005108951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_223171565.1"
                     /translation="MAQQRQDRRGEVQAATASATGLACFIFRFLRRPLVVCGLAWQGAG
                     IFNLPFTVMLWTIIRLIIVVSLVFITGKFGLSREFTFPAAAVGLAFSLFPVLDHIALGY
                     SAKNFYETTNFMGQTVREFGASKITVWWGSIYAKIAYASLAGLIGYGVKVATDD"
                     /name="hypothetical protein"
     gene            complement(4131..>6527)
                     /locus_tag="JJB19_RS25160"
                     /old_locus_tag="JJB19_25155"
                     /pseudo=""
     CDS             complement(4131..>6527)
                     /locus_tag="JJB19_RS25160"
                     /old_locus_tag="JJB19_25155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004726714.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element TnAs3 family transposase"
                     /name="Tn3-like element TnAs3 family transposase"
     gene            complement(6577..7281)
                     /locus_tag="JJB19_RS25165"
                     /old_locus_tag="JJB19_25160"
     CDS             complement(6577..7281)
                     /locus_tag="JJB19_RS25165"
                     /old_locus_tag="JJB19_25160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            <7347..8861
                     /locus_tag="JJB19_RS25170"
                     /old_locus_tag="JJB19_25165"
                     /pseudo=""
     CDS             <7347..8861
                     /locus_tag="JJB19_RS25170"
                     /old_locus_tag="JJB19_25165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138014.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element TnAs1 family transposase"
                     /name="Tn3-like element TnAs1 family transposase"
     gene            complement(9002..9793)
                     /locus_tag="JJB19_RS25175"
                     /old_locus_tag="JJB19_25170"
     CDS             complement(9002..9793)
                     /locus_tag="JJB19_RS25175"
                     /old_locus_tag="JJB19_25170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_050394548.1"
                     /translation="MTKKTLAERFEVLEQEYNSVMSTKYMGTSAFSHRSQEYIDSARSN
                     NWIARAKKLLEDSYGKESDYYKDFNDTQRIAWSSNYQGLVKHYKPIFDAARDDLTYSGT
                     ASTIATKHAELDLIINILNKFPAFCRQLKQRYNERTPLEINDEYDVQDLVHALLLLHFD
                     DVRPEENSPSFAGSSSRQDFLLKKEKIVIEVKKTRRSLGANKIGEELLIDMARYRAHPD
                     CETLVCFVYDPEGWVTNPKGVIDDLEGKDTEGKTRVVIAQF"
                     /name="hypothetical protein"
     gene            10764..10847
                     /gene="dinQ"
                     /locus_tag="JJB19_RS25180"
                     /old_locus_tag="JJB19_25175"
     CDS             10764..10847
                     /gene="dinQ"
                     /locus_tag="JJB19_RS25180"
                     /old_locus_tag="JJB19_25175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165328.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible type I toxin DinQ"
                     /protein_id="WP_000565612.1"
                     /translation="MIDKAIIVLGALISLLELIRYLLQLMG"
                     /name="dinQ"
     gene            complement(11002..11646)
                     /locus_tag="JJB19_RS25185"
                     /old_locus_tag="JJB19_25180"
     CDS             complement(11002..11646)
                     /locus_tag="JJB19_RS25185"
                     /old_locus_tag="JJB19_25180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001503708.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001376796.1"
                     /translation="MTSNVPTSFVRAYLRASTAEQDASRALETIEAFARERDLIICSYY
                     IENESGSRLERPELFRLLRDCQQNDILLIEDVDRLSRLSGEDWNTLKKMIRQKDIRVMA
                     VNVPTTWINSGMSEFDSRLFAAINDMLLDMLAAVARRDYEQRRERQKQGIEKARKDGKY
                     KGRKPNQARHDAIIRLIESGSSWTQVQKVLGCSRGTISNALKRKTGQKSSK"
                     /name="recombinase family protein"
     gene            11939..12559
                     /locus_tag="JJB19_RS25190"
                     /old_locus_tag="JJB19_25185"
     CDS             11939..12559
                     /locus_tag="JJB19_RS25190"
                     /old_locus_tag="JJB19_25185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864791.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_001376797.1"
                     /translation="MKVISFLNPKGGSGKTTAVINIATALSRSGYNIAVVDTDPQMSLT
                     NWSKAGKAAFDVFTAASEKDVYGIRKDLADYDFAIVDGAGSLSVITSAAVMVSDLVIIP
                     VTPSPLDFSAAGSVVTVLEAQAYSRKVEARFLITRKIEMATMLNVLKESIKDTGVKAFR
                     TAITQRQVYVKSILDGDSVFESSDGAAKGEIEILTKEIVRIFE"
                     /name="ParA family protein"
     gene            12611..12841
                     /locus_tag="JJB19_RS25195"
                     /old_locus_tag="JJB19_25190"
     CDS             12611..12841
                     /locus_tag="JJB19_RS25195"
                     /old_locus_tag="JJB19_25190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid partition protein ParG"
                     /protein_id="WP_000051066.1"
                     /translation="MSLEKAHTSVKKMTFGENRDLERVVTAPVSSGKIKRVNVNFDEEK
                     HTRFKAACARKGTSITDVVNQLVDNWLKENE"
                     /name="plasmid partition protein ParG"
     gene            12857..13168
                     /locus_tag="JJB19_RS25200"
                     /old_locus_tag="JJB19_25195"
     CDS             12857..13168
                     /locus_tag="JJB19_RS25200"
                     /old_locus_tag="JJB19_25195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000358386.1"
                     /translation="MDKKIVDALRTLLEALPEEVITEVTSKLNPSANHIPEENSKQLIA
                     KARVLNFRLTEVYKEILEAEASRTRQSKTTILKAALAAFDSLDENRKNHWLLESAKLG"
                     /name="hypothetical protein"
     gene            13553..13726
                     /locus_tag="JJB19_RS25205"
                     /old_locus_tag="JJB19_25200"
     CDS             13553..13726
                     /locus_tag="JJB19_RS25205"
                     /old_locus_tag="JJB19_25200"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="WP_215249975.1"
                     /translation="MEKTEASKLIKEHEKQENIEPYGYILLIKKAALLVLSFAALFDFI
                     ILLFDYSSPKSP"
                     /name="aminopeptidase"
     gene            13815..14102
                     /locus_tag="JJB19_RS25210"
                     /old_locus_tag="JJB19_25205"
     CDS             13815..14102
                     /locus_tag="JJB19_RS25210"
                     /old_locus_tag="JJB19_25205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001722376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcxB family protein"
                     /protein_id="WP_227636918.1"
                     /translation="MKKIMRSNHSSEIKDQELMLRLKINRSYIEQVMKIGSSRVFWNNI
                     KKTYRKQGFLFIQTKENRCIIIPERVFKNEEETEKLYNFVKEKIAQNTME"
                     /name="YcxB family protein"
     gene            14120..14980
                     /locus_tag="JJB19_RS25215"
                     /old_locus_tag="JJB19_25210"
     CDS             14120..14980
                     /locus_tag="JJB19_RS25215"
                     /old_locus_tag="JJB19_25210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001714235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6685 family protein"
                     /protein_id="WP_063122221.1"
                     /translation="MMNIVNTIEFMVKDINKYLDDITLNAITVDGKTILKLEDMSNKNI
                     SPRLEKILRKLIKIEVEHIHNFDFSKLQSLENSKSFEHLPAKSKNPSCYRDLYSWGKGM
                     RHTEKLRAEDESDWKKNIQHIEEEGFRRNRPIEITYYTWLDRYFVSNNGGSHHAALVVW
                     QSVRDKLEYKREANITKLSIDKVSIKKLNSDYWSFILNFRYQTNINTLFNLFNSLVSKH
                     TDMLEPSHYHGNYRLFFVPKSQLKMNKYAFEYWYRNSVKNKKIIALPEYLENPLQFHTG
                     GILIQ"
                     /name="DUF6685 family protein"
     gene            complement(15001..15357)
                     /gene="ddp1"
                     /locus_tag="JJB19_RS25220"
                     /old_locus_tag="JJB19_25215"
     CDS             complement(15001..15357)
                     /gene="ddp1"
                     /locus_tag="JJB19_RS25220"
                     /old_locus_tag="JJB19_25215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001694624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA distortion polypeptide 3"
                     /protein_id="WP_001714234.1"
                     /translation="MKYQVRKFITDKYAKAVNILKDNLKEHYHVFYGVRLSEILFPAGE
                     YGSEQFFSDFEKINSILLPLLVFDLKTDVPVIVISLDDVSYCDVLNEIDIDFMKCNSLA
                     ELLTSDKLDALFKD"
                     /name="ddp1"
     gene            complement(15494..15940)
                     /locus_tag="JJB19_RS25225"
                     /old_locus_tag="JJB19_25220"
     CDS             complement(15494..15940)
                     /locus_tag="JJB19_RS25225"
                     /old_locus_tag="JJB19_25220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001074384.1"
                     /translation="MAKIYQFPQGEERAKFRKEIARERKKRFAVKTGSTFVKWLGWGWF
                     YLRLLAASVLHFIFVFVLAILGAFKWAVFWLGGILCVITWYHLDHQLWTPQNLTIPVIT
                     ATWILGLLAEPLMELLNKTMPWHKLLVPEPADESTENSSEISQQ"
                     /name="hypothetical protein"
     gene            complement(15944..16786)
                     /locus_tag="JJB19_RS25230"
                     /old_locus_tag="JJB19_25225"
     CDS             complement(15944..16786)
                     /locus_tag="JJB19_RS25230"
                     /old_locus_tag="JJB19_25225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435061.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000435064.1"
                     /translation="MEQIKLHKQGGAAVIIIPASMIENTGWEDGTLLEVLEINETLHIR
                     RKTESGALATKACPSLFSSTMRHVNYDKIIRYNSGLNLLVNELSFSARRVFFICLYYYF
                     ENKLESDKSLLIRADKYAEFVGVERSVAYKQMKDAADFFSRNKNLITHCDYISNEGLLR
                     VMFSSKTINYITAIDSRKYQVTELPLKSALSLQGRYSWPLYQLIKFSHLKSFTIGVDEL
                     KKEIGYIQNQKFSFFKRDGINIAIDEITERTDVKNIKCVNAERQGRRVSKVRFEIEMR"
                     /name="replication initiation protein"
     gene            complement(16807..17646)
                     /locus_tag="JJB19_RS25235"
                     /old_locus_tag="JJB19_25230"
     CDS             complement(16807..17646)
                     /locus_tag="JJB19_RS25235"
                     /old_locus_tag="JJB19_25230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001722379.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_001352874.1"
                     /translation="MNLLSVTKKTKIRHRNEINSTFSSLPLSARRILFMAMAQIDSREE
                     LSEGATFRITAREYAFIADIDVTGAYRQLKEGAEELQASVIRIPRNQLLTAQGNQSSGH
                     TKKRGKLPSDAVRLMNLTAFCDYVESEGYIDIAFSHVIEPYITMLKDSYTTQVLISSVR
                     LADQNSNMLYQFIRKQYSSGKKTFFDIEVDVLKDELELFRIDNGEKVYLYQNFKDFNKV
                     FLQKNIEKINQYTEINHLEVKIVERVARRASKLRFSYKIDKESEGLDTRIPYGFRGA"
                     /name="replication initiation protein"
     gene            18881..19132
                     /locus_tag="JJB19_RS25240"
                     /old_locus_tag="JJB19_25235"
     CDS             18881..19132
                     /locus_tag="JJB19_RS25240"
                     /old_locus_tag="JJB19_25235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000121741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="WP_000121743.1"
                     /translation="MSYQILTTTAASITDLKKNPMGTVAEGEGDAVAILNRNEPAFYCV
                     PPKLYAYYRELAEDAELNAVADERMKNPEIVKVNLDDL"
                     /name="plasmid stabilization protein"
     gene            19122..19403
                     /locus_tag="JJB19_RS25245"
                     /old_locus_tag="JJB19_25240"
     CDS             19122..19403
                     /locus_tag="JJB19_RS25245"
                     /old_locus_tag="JJB19_25240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001694627.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_000220561.1"
                     /translation="MTYELAFDRRALKEWQKLGHTIREQFKKKLAERLENPRVPAARLH
                     GHADRYKIKLRASGYRLVYQVIDEKVVLLVIAVGRRESSEVYQIADMR"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            19753..20268
                     /locus_tag="JJB19_RS25250"
                     /old_locus_tag="JJB19_25245"
     CDS             19753..20268
                     /locus_tag="JJB19_RS25250"
                     /old_locus_tag="JJB19_25245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025391.1"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="WP_001025387.1"
                     /translation="MNIQEALNIFGLSGDLTEKDIKAAYRKAALKYHPDRNPLGAELMK
                     AVNAAFDFLMANIDKINQFQSTDENARYNYGEDLEKVLNTLSGLTGIVYEVIGNWVWIS
                     GETITHKETLKEIGCKWAAKKKQWFYRPEEHKSYWNREEHTIEEIRAKYGSTGQRRATG
                     WQQVETRA"
                     /name="J domain-containing protein"
     gene            20342..20890
                     /locus_tag="JJB19_RS25255"
                     /old_locus_tag="JJB19_25250"
     CDS             20342..20890
                     /locus_tag="JJB19_RS25255"
                     /old_locus_tag="JJB19_25250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001178641.1"
                     /translation="MQNDKFFERYQPVFEIVCRILGNGWRVNLLDDCQYRIKLTSPQYK
                     NYSIHIRMEKGRLVIIGSVDSRSWRSPYHTCTVSPERNPVEIAADIEKKILTDAFENVE
                     KAMEYERQLQKKREQTQILKGMLSRLIRLDSWHGTLTGFKVENGLDGNVSERGGGFEMV
                     IRGLSVDQLIKVAGFIKQL"
                     /name="hypothetical protein"
     gene            20899..21168
                     /locus_tag="JJB19_RS25260"
                     /old_locus_tag="JJB19_25255"
     CDS             20899..21168
                     /locus_tag="JJB19_RS25260"
                     /old_locus_tag="JJB19_25255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001006718.1"
                     /translation="MNEVLSDRKNKGNVTYRIVVSEDATRLFIELEKLMKVRSKEADKK
                     TTKKVVFHKSFYYEEFCNVKDEIDDPILLQFYTDTIVKVLNHEF"
                     /name="hypothetical protein"
     gene            21158..21400
                     /locus_tag="JJB19_RS25265"
                     /old_locus_tag="JJB19_25260"
     CDS             21158..21400
                     /locus_tag="JJB19_RS25265"
                     /old_locus_tag="JJB19_25260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000008708.1"
                     /translation="MSFKPTPEEVKQARIKAGFTQQEAAKRFGFSLSAWQAKETSGKTS
                     RGLAAGTYELLLLLADEHPDYQLVKREKNQNKETK"
                     /name="hypothetical protein"
     gene            21533..22237
                     /locus_tag="JJB19_RS25270"
                     /old_locus_tag="JJB19_25265"
     CDS             21533..22237
                     /locus_tag="JJB19_RS25270"
                     /old_locus_tag="JJB19_25265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            22243..22383
                     /locus_tag="JJB19_RS25275"
                     /old_locus_tag="JJB19_25270"
     CDS             22243..22383
                     /locus_tag="JJB19_RS25275"
                     /old_locus_tag="JJB19_25270"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001044210.1"
                     /translation="MNKTKGCLIANFATVPRDEQQHQEQKHVEKKQQQIEQRPRRAARI
                     G"
                     /name="hypothetical protein"
     gene            22869..23606
                     /locus_tag="JJB19_RS25280"
                     /old_locus_tag="JJB19_25275"
     CDS             22869..23606
                     /locus_tag="JJB19_RS25280"
                     /old_locus_tag="JJB19_25275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001370723.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001446887.1"
                     /translation="MRRTKPVAAPMVARVYLRVSTDAQDLERQEAITTAAKAAGYYVAG
                     IYREKASGARADRPELLRMIGDLQPGEVVIAEKIDRISRLPLPEAERLVASIQAKGASL
                     AVPGVVDLSDLAAEAQGVAKIVLEAVQIMLFRLALQMARDDYEDRRERQRQGIELARQA
                     GRYKGRRADPKRRAQVVALRKSGYSINKTAELAGYSAAQVKRIWAEVSQAEAKQHGAFV
                     EDALTEADALAAVGQDERQEERA"
                     /name="recombinase family protein"
     gene            23603..23827
                     /locus_tag="JJB19_RS25285"
                     /old_locus_tag="JJB19_25280"
     CDS             23603..23827
                     /locus_tag="JJB19_RS25285"
                     /old_locus_tag="JJB19_25280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000743213.1"
                     /translation="MKKPNQDDEPFFITEEIAAEMIAGGYEFELPPIPCTIRLRDVLER
                     MTDAELALQPGEIADQERERCRRKPCSTS"
                     /name="hypothetical protein"
     gene            24038..>24775
                     /locus_tag="JJB19_RS25290"
                     /old_locus_tag="JJB19_25285"
                     /pseudo=""
     CDS             24038..>24775
                     /locus_tag="JJB19_RS25290"
                     /old_locus_tag="JJB19_25285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001120888.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="transposase zinc-binding domain-containing
                     protein"
                     /name="transposase zinc-binding domain-containing protein"
     gene            complement(<24755..25144)
                     /locus_tag="JJB19_RS25295"
                     /old_locus_tag="JJB19_25290"
                     /pseudo=""
     CDS             complement(<24755..25144)
                     /locus_tag="JJB19_RS25295"
                     /old_locus_tag="JJB19_25290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001120888.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="transposase zinc-binding domain-containing
                     protein"
                     /name="transposase zinc-binding domain-containing protein"
     gene            complement(25256..25561)
                     /locus_tag="JJB19_RS25300"
                     /old_locus_tag="JJB19_25295"
     CDS             complement(25256..25561)
                     /locus_tag="JJB19_RS25300"
                     /old_locus_tag="JJB19_25295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001255015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_001255015.1"
                     /translation="MRRTNHRNLVNVGILSGRIPLISLVQFIAVAEHLNFRHAAKALGI
                     SQSSVSARVKALEDNLGVLLFERHARGVRLTDAGRHFMERVTAGVDQLDHAVKTAE"
                     /name="LysR family transcriptional regulator"
     Typing          complement(15495..15940)
                     /name="IncX1"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.776"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gccgtaaagt tcgccgatcc ccaacaggac cgctccgcaa acaagcaacg ccatcccacg
       61 cgccacgcat cctgcgatgc cccatctggc gacaaaggac ttcgcgaaac gggttgtcac
      121 gatcattaca agcgcgacag tggcgaaggc aaagctgaat ccgatctcgg aatattccgc
      181 ttggcctatg agcacacggg gagccgtcga gaagaagacg aagtaggtgc ccataccggc
      241 gctaaagccg acagtgtaaa cccaaaaagc cggactcgcg aagatcggca agacagatcg
      301 gcgcgtcttg acttgatcca gagggcgggt ttcgtgccac ctgaaacccg catttaggag
      361 tgcgagcatc gccagtatag ccaaagtaat gaatatcgcc tgccatccca agaactcgcc
      421 gatcaatgtt ccggcgatag ggccgagcgc aggcacgaac gccagcatcg aactgaaaag
      481 gccgtagatg acgacaccct caggacggtt ggcataaacg tcgcgaaccg tcgcgaacgt
      541 cgccaccagc atggccgacg cgcccactgc ttgaagtaga cggaaagcga caaaggccgg
      601 tgcagttgaa gaccaagctg ctcccagaga cgcaatgacg aaagccgttg cgcccgcaag
      661 tagaattggc cgtcgcccga ttctgtctga gagcggacca aaaatcacct ggcccacgcc
      721 gagcatcacc atatagaggc tcaacgtgag ttggatcata gcgggcgtcg tgttcaggat
      781 gccgggcatc gctggaacga cagggagata aatatccatc gccagtgaag cgaggatgtc
      841 gaaaggagcc atcagcagca gtgctgccgg cagcgtatag gcccacgcgg ggcgtgtggt
      901 ggtcatgacg aatcaaccct cgattaagga ataccgggcg acgtctgctc gtcagcaatc
      961 agatgagact agccttacag agcgccgcaa caacaatact ggttgttgcg gcttacttgt
     1021 ctgctgactt ggaatttccc atctgattac tccacgctta cgaatatgaa ttgctacatt
     1081 ttatccgatt atcttttgct tcgcaatgcg gcatgggcgc actcagcgtt ccagccccct
     1141 ctgccgccct aactgccacg acaccgaccc gccctgcacg atgcccataa cctcgcggcc
     1201 gagttggcgg tcgatgatcg gccgccacgg gacaagggtg aactcatggg atttctcgac
     1261 cacggcgaac ttgccgctcg atagatgcac ggttccggta aacttgccgc tgacgctctc
     1321 gccgtccgtg gcggcgcgga acggcaggcc cttactcaaa gccatatccg atccgacgcc
     1381 ggctacctcg cgctcccgca ggatggcgag aaggttgcgc cggtagaaga cgcggctgtc
     1441 ccggctgcgg gtggcgtcgc cctgttcgat atggtgctcg cggcgctggt ccatggcttc
     1501 gcggacttgt tgcccgaagc cggttggcgc aaggtcggcc gtctcgccgt ggatcagccg
     1561 ccggtccagc caggtcgcgc cgtccgatcc gatctgtttg ttcagatcga ccggggaaag
     1621 gacgcgaacg ctggcctgac tgtctcggcc ggcgtcatgg gcggcggcac ggctgaccag
     1681 atcatcgggg atgcgccatt ggtcggcgtc gatccgctcg acgataccgg cccggcgtag
     1741 cgcctccagc cggcgcacat gggcatcgac atagccctca tagtcgccgc ctggaacgcg
     1801 gcacgtatag gaagaataaa cgcccttttc acccaagtcc aacagctttg gaccgcagtt
     1861 gactctttcg acacccctgc gatgcaaccc aatccggctg acggggagcc agcaacgctg
     1921 aaaatttacc ctcctctttc ccactagcgg ctccttttcc gacaaccagc acggcggatc
     1981 cctgccgcgg cgctgtgaac gcagcatttt gattggtatc gttggccttc aggctcgtca
     2041 gtcaaacaga cccaggagca gctcagccgg tggcgcccgg ctttcgggta acgccctggt
     2101 cccgctggtt tcggctttgt gcttcaggtg atcaaggatc tgcttgatca ctatagggtc
     2161 ttcaatgcag gcgatgactt tcatggcgcc gccgcagccg ctgcaggtct cgatgtcgat
     2221 attgaaaaca cgcttgagcc gttgcgccca tgtcatcgac gctcgccgtt gtgctggtgt
     2281 tgccggttca tcagccaccc tgaccttgtt gcccctgccc cgttttgccg gcgtgaccaa
     2341 cgcccggtgc cgactgttgg gtgcgaacac cccgtggaag cgggttaggt tgactctggg
     2401 cttcggtacc agggcggcca gccttgcaat gaaatccaat ggttcgaaaa tgacgtgcgt
     2461 ggtgccgtcc cggtacggcg tcttgagctg gtagcgcacg ttgccgcctc gtgttaacga
     2521 cagccgcttc tcggataccg ccgggcggct gatgtaccgg cacagccgtt cgagcttctt
     2581 gcgttcatcg gccctggccg ccacgccggc gtgcaggctg gacccggcta ccttgccaat
     2641 cccgtcaccg aacggatcac cactggtcgg cagagtttgc aaagtgaaca cctttcgccc
     2701 cgcctgtgaa ccgacagcga tacggtaagt gatcgagtgc cccagcaggg gtgtcatcgg
     2761 gtcgtcatcc accgcatccg aggccagata gctgttttcg acatcccgtt ccagcaggcc
     2821 ttgccgttcc agatagcgac ccacccggtg ggcgatggtg tgcgtcagcg gcactgttgc
     2881 aaataaccac gaatggtaag ctgaagactg ttttagctaa aggtgcagca tatgaatcct
     2941 ttccatggtc ggcattttca gggcgaaatc attctttggg ctgtgcgctg gtattgtaaa
     3001 tatggcatta gctatcgtga actgcaggaa atgctggccg aacggggtgt gaatgttgat
     3061 cacacgacta tttaccgttg ggttcaacgt tatgctcctg aaatagaaaa acgtttacgc
     3121 tggtattggc gtaatcctac agatctgagc tcgtggcata ttgatgaaac ctatgtaaaa
     3181 gtgaatggac gatggtctta tctgtatcgt gcagtcgatc aacgtggcga taccattgat
     3241 ttttatcttt cttctagacg taataccaaa tcagcatatt gttttcttgg aaaaatttta
     3301 aataatgtga agaagtggca aattccacaa gtgatcaaca cggataaagc acccacatat
     3361 ggacgtgctt tatcacggtt aaaacgggaa ggtaaatgtc caccagacct tgagcacagg
     3421 cagattaagt ataaaaataa cgtgattgaa tgtgatcatg gcaagctaaa gcggatcatc
     3481 agggccacat taggattcaa atctatgaag acggcttatg ccacaattaa aggtattgaa
     3541 gtcatgcgtg cactacgtaa aggacaagca tcgtcatttt attatggtca gcctcagggt
     3601 gaagtgtgtc taatcaacag ggttttcggt ctctaagtac tttttaaagg gaacatcatc
     3661 gactcaaatc tctatttgca acagtgccaa aaaaaccaac ttcaagttgg tttttctttt
     3721 ttaatcatca gtggcgacct taacaccata tccaattaaa cctgcaaggc tagcataggc
     3781 tattttggca taaatcgaac cccaccagac cgtaatttta ctggcaccaa attcccgaac
     3841 cgtttgcccc ataaaattag tggtttcata gaaattttta gcagaataac ctaacgcaat
     3901 atgatcaagg acagggaata aactaaaagc taaacctact gctgctgcgg ggaaagtaaa
     3961 ctctcttgat agaccgaatt ttccagtaat aaatacaagc gataccacga taattaatct
     4021 aatgatagtc catagcatca ctgtgaaagg caagttaaag atgcctgctc cctgccacgc
     4081 aagaccgcaa acaactaggg gtcgtctcag aaaacggaaa ataaagcacg ctaagccggt
     4141 tgcagaggcc gtagcggcct gaacttcccc gcgccgatct tggcgctgct gcgccatagg
     4201 taatcaccgg tcaggttgat gtgctcccag ccgagtggcg acaggtactg caatagcgag
     4261 tcatcgacgg catgaccatt gccgcgcaac gcatgcgccg cacgctccag gtagaccgtg
     4321 ttccacagca cgatggccgc cgtcaccagg ttgaggccgc tggcccggta gcgctgctgc
     4381 tcgaaactgc ggtcacggat ttcaccaagg cggttgaaga acacggcacg ggccagcgca
     4441 ttgcgcgcct cgcccttgtt cagcccggca tgcacgcggc ggcgtagctc gacgctttgc
     4501 agccagtcga ggatgaacag cgtgcgctcg atgcggccca actcgcgcag cgcgacggcc
     4561 aagccgttct ggcgcgggta gctgccgagt ttcctgagca tcagcgaggc cgtcaccgtg
     4621 ccctgcttga tcgaggtggc cagccgcagg atttcgtccc aatgggcgcg gacgtgcttg
     4681 atgttgagcg tgccgccgat catcggcttg agcgcgtcat aggcggcatc gcccttcggg
     4741 atgtagagct tggtgtcgcc caggtcgcgg atgcgcggcg cgaagcggaa gcccaagagg
     4801 tgcatcaggg cgaagacgtg atcggtgaag cccgccgtgt cggtgtagtg ctcctcgatc
     4861 cgcaggtcgg attcgtggta cagcaggccg tcgagcacgt aggttgagtc gcgcaggccg
     4921 acattgacca ccttggtgtg gaatggcgcg tattggtcgg agatgtgggt gtagaaagtc
     4981 cgtcctgggc tgctgccata ttttgggttg atgtgccccg tgctctttgc cttgctagcg
     5041 gttcggaaat tctgtccgtc cgatgatgat gtggtgccat cgccccagtg cccggcaaag
     5101 ggatgccgaa actgagcgtt gaccagttca gccaacgctg tcgagtacgt ttcgtcgcgg
     5161 gtatgccagg cttgcagcca agcgagcttc gcgtaggtcg tgccggggca ggactcggcc
     5221 atcttggtca ggcccaggtt gatcgcgtcg gccaggatcg tggtcaacaa caggttcttg
     5281 tccttggcca gatcgcccga tttcaagtgc gtgaagtgcc gggtgaagcc cgtccactca
     5341 tcgacttcga gcagcagttc ggtgatcttg acgtgcggca ggaccatggc tgtctggtct
     5401 atcagcgcct gcgcggtgtc gggcaccgcc gcatccagcg gcgtgatctt caagcccgac
     5461 tcggtgatga tggcatccgg caggtcgttg gctgccgcca tgcggttgac ggtggcaagt
     5521 tgtgcttcca gcagcgtcag ccgctcatgc agatattgtt cgcagtcggt ggccacggcc
     5581 agcggcaatt cgctggactg cttgaggctg gtgaacttct cgggcggtac caggtagtcc
     5641 tcgaagtcct tgaactggcg tgaaccctgc acccagatgt cgcccgagcg cagggagttc
     5701 ttcaactcgg acagcgcgca cagttcgtag tagcgccggt cgatgccggc gtcggtcatc
     5761 accagtttct gccagcgcgg cttgatgaag ccggtcggtg catcggctgg cagcttgcgg
     5821 gcgttgtcgg tgttcatgcc gcgcagcacc tcaatggcat caagcacgtt tttggcggcg
     5881 ggcgcggccc gcagcttgag cacggcaagg aattccggtg catagcggcg cagggtggcg
     5941 tagctctcgc cgatgcgatg caggaaatcg aagtcatcgg gttgcgcgag cttctgcgcc
     6001 tcggtgacgc tctcggcaaa ggaatcccag gacatgacgg cctcgatggc ggcaaacgca
     6061 tcgcggcctg attgcttggc gtcgatcagc gcctgaccga tgcgcccgta cagacgtacc
     6121 ttggcgttga tggccttgcc tgacgcctgg aactgctgct gatgcttatt cttggcagcg
     6181 ttaaacagct tacccaggat gcggtcgtgc aggtcgatga tttcgtcggt gacggtggcc
     6241 agcgccacga gagtggcgta gcgccgttgc ggctcgaatt tggccaggtc ggcgggtgtc
     6301 atctggccgc cctcgcgggc aatcttgagc aggcggttct ggtgaaccag ccgctcgatg
     6361 ccggtaggca gatcgagtgc ctgccatgcc ttgaggcgtt cgatgtgttc cagcatatgc
     6421 cgcgaatttg gcttggccgg agactggcgc aaccaagcca accaggtcgt cttgccgttg
     6481 tcccggcgct tgagcagatc gtcgaggcgg cggcgatgcg cgtcggcact gttgcaaagt
     6541 tagcgatgag gcagcctttt gtcttattca aaggccttac atttcaaaaa ctctgcttac
     6601 caggcgcatt tcgcccaggg gatcaccata ataaaatgct gaggcctggc ctttgcgtag
     6661 tgcacgcatc acctcaatac ctttgatggt ggcgtaagcc gtcttcatgg atttaaatcc
     6721 cagcgtggcg ccgattatcc gtttcagttt gccatgatcg cattcaatca cgttgttccg
     6781 gtacttaatc tgtcggtgtt caacgtcaga cgggcaccgg ccttcgcgtt tgagcagagc
     6841 aagcgcgcga ccataggcgg gcgctttatc cgtgttgatg aatcgcggga tctgccactt
     6901 cttcacgttg ttgaggattt tacccagaaa ccggtatgca gctttgctgt tacgacggga
     6961 ggagagataa aaatcgacag tgcggccccg gctgtcgacg gcccggtaca gatacgccca
     7021 gcggccattg accttcacgt aggtttcatc catgtgccac gggcaaagat cggaagggtt
     7081 acgccagtac cagcgcagcc gtttttccat ttcaggcgca taacgctgaa cccagcggta
     7141 aatcgtggag tgatcgacat tcactccgcg ttcagccagc atctcctgca gctcacggta
     7201 actgatgccg tatttgcagt accagcgtac ggcccacaga atgatgtcac gctgaaaatg
     7261 ccggcctttg aatgggttca tgtgcagctc catcagcaaa aggggatgat aagtttatca
     7321 ccaccgacta tttgcaacag tgccacttcg acgactacct gctgccggcc gagaagttcg
     7381 ccgcactcaa gcgcgagcag gccctgcccc tggcgatcaa cccgaacagc gaccagtacc
     7441 tggaagagcg tttgcagctg ctggacgagc agttggccac cgtcacccgc ctggccaagg
     7501 acaacgagct gcccgatgcc atcctcaccg agtcagggct gaaaatcacc ccgctggatg
     7561 cggcggtgcc ggatcgggcg caggcgctga tcgaccaaac cagccagtta ctgccgcgca
     7621 tcaagatcac cgaactgctg atggacgtgg acgactggac gggcttcagc cgccacttca
     7681 cccacttgaa ggacggggcc gaggccaaag acaggacgtt gctgctgtcc gcaatcctcg
     7741 gtgatgcgat caacctcggg ctgaccaaga tggccgagtc gagccccggc ctgacctacg
     7801 ccaagctgtc ctggctgcaa gcctggcaca tccgcgacga aacctattcg gcggccttgg
     7861 ccgagctggt caaccaccag tatcgccacg cctttgccgc ccactggggc gacggcacga
     7921 cctcatcctc cgatggccag cgcttccgcg cgggtggccg gggcgagagc accgggcacg
     7981 tcaacccgaa gtacggtagc gagccgggac ggctgttcta tacccatatc tccgaccagt
     8041 acgcgccgtt cagcacccgc gtggtgaatg tcggcgtccg cgattccacc tatgtgctcg
     8101 acggcctgct gtaccacgag tccgacctgc ggatcgagga gcactacacc gacacggccg
     8161 gcttcaccga tcacgtcttt gccctgatgc acctgctagg cttccgcttc gcgccgcgca
     8221 tccgcgacct cggcgaaacc aagctgtacg tgccgcaggg cgtgcaagcc tacccgacgt
     8281 tgcgcccgct gatcggcggc accctgaaca tcaagcacgt gcgtgcccac tgggacgaca
     8341 tcctgcgcct ggccagctcg atcaagcagg gcaccgtcac cgcctcgctg atgctgcgca
     8401 agctcggcag ctacccgcgc cagaacggac tggccgtggc cctgcgcgag ctgggccgga
     8461 tcgagcgcac gctgttcatc ctggactggc tgcaaagtgt tgaactgcgc cgccgcgtgc
     8521 atgccggcct gaacaaaggt gaggcgcgca actcgctggc cagggcggtg ttcttcaacc
     8581 gccttgggga aatcagggat cggagcttcg agcagcagcg ctaccgggcc agcggcctca
     8641 acctggtgac ggcggctatc gtgctgtgga acacggtgta cctggaacgc gccacccagg
     8701 ggttggtcga ggccggcaag ccggtggacg gcgagctgct gcaattcctg tcgccgctgg
     8761 gctgggagca catcaaccta accggcgatt acgtctggcg gcagagccgc agactggaag
     8821 acgggaagtt tcggccctta cggatgcccg gaaaacctta gcgtacgatt ttttccgaat
     8881 tctgcgggct cccccttata gaagattatc ggcattatag gaaggttgac actggttgta
     8941 gtacgatcac aattcctcgc acacttggac atacaggtga ttctgtccag catagtgaaa
     9001 atcagaactg agctatcacg actctagtct ttccttcggt atctttcccc tcaagatcgt
     9061 ctatcacacc tttagggtta gtcacccaac cttcagggtc gtatacaaag catactagcg
     9121 tctcacagtc cggatgtgca cggtaacggg ccatatcaat gagcagttcc tctccaattt
     9181 tatttgcccc tagagagcgg cgagttttct tcacttcaat gacaatcttc tctttcttca
     9241 gaagaaaatc ctgtctggat gatgaacctg cgaagctagg tgaattttct tcaggtctga
     9301 catcatcaaa atgcagcagc agaagagcat gaacaagatc ctgtacatca tactcgtcat
     9361 taatctcaag cggcgttctt tcattgtatc gttgctttaa ttgacgacaa aaagctggaa
     9421 atttattgag tatatttata atcaaatcca gttctgcatg ttttgttgct atagtcgatg
     9481 ccgtgccgga gtaagttaaa tcgtctctgg ctgcatcaaa aataggtttg taatgtttaa
     9541 ccaatccctg ataattacta gaccaagcaa tcctttgtgt atcattaaaa tctttgtagt
     9601 aatcagattc ctttccataa ctgtcttcaa gtaacttttt tgctcttgca atccagttat
     9661 tacttctagc cgaatcaata tattcctggc ttctgtgact aaatgcactt gttcccatat
     9721 attttgtcga catgacagaa ttatactctt gttcaagcac ttcaaatctt tcagctaagg
     9781 tcttcttcgt catagtgcaa tccaaattat atgctaataa tatctgtgaa ttttaatatt
     9841 ctaccatgtc tggctttctt ccgttcacat tggacattca ggtaattctg tccataccta
     9901 attagttaca acattcacat gttctgttcc tttatctggt gccctgttcc gacatatgtg
     9961 cccatatcct gggttattca ggataaccgc ttccttttca ccctgccctg tcgttcatat
    10021 tcctctggac aaaaatgcat tatcggaaaa aatgtccaaa tttttttttg gtgatcggaa
    10081 tttttgttgt cggacgcacc tctgcttcag gtcataattg ctggcacgtc cagaaaaaca
    10141 ggtgcggaga ttaaaaaatt gagtcactta cccgccaaaa ttttccagat ttcacgtagc
    10201 acaccaccgc tactgcatcc atcaacaaaa aatgacgttt ttttaattac tttgtatgct
    10261 gcaacttact gaaaaaacgg gattcatgat aatgccggta acggcatcgt tctgttggcc
    10321 aacgcgatca gcagtattgg ctgcaacaaa aaataaaaga aaaatccctc aaatgaaggg
    10381 gaaaaaacgg aagtacaggc aaacgacagg cacaaaaaaa cccgacgggt aatcgggctt
    10441 ttttgtgttt tccagccctg agttggtggc tctgactgga gaagaactct cttcaaccaa
    10501 catagacata atatgtctac atgatatgga atgcaaccgt atccgcttat gcgtataata
    10561 caccggttgg ttctgatccg ttataactcc agccttcccg caaggattaa gcgattttaa
    10621 gtcctggctg aaaaacaggt ggtgctgttg tcagtgctct ggctggagtg gaactgtctt
    10681 caaccaacac cgaagaacaa ccgatatgac aggcagtgta agagtaagta tcgggagtct
    10741 gctccatata atggagtaaa cggatgattg ataaagcaat catcgttctg ggggcactaa
    10801 tctcgcttct tgaactgatt cgctaccttc tccagttgat gggctgatgg cggaaacgta
    10861 actaaggccg ggggctaacc acctccggcc tttaataaaa acatatttta gttacaatat
    10921 tcaaatgcat tgactaaaca ccacacaccc aatctcctga gttaatatcc tgccttgcag
    10981 gtatattagc cccctactcc tctacttact ggatttctgc ccggttttac gttttagcgc
    11041 attactgatt gtgccacggc tgcaccctag cactttctgt acctgtgtcc aggagctacc
    11101 gctttctatc aacctgataa ttgcatcatg tctggcttga ttaggtttac gccctttata
    11161 tttgccgtct ttccttgctt tctctatccc ttgtttctgg cgttccctac gttgttcata
    11221 gtcccttctg gcaactgcgg ccagcatatc cagcagcata tcgttaatgg ctgcaaacaa
    11281 ccggctgtca aactcactca taccagaatt aatccatgtc gtcggcacat tcaccgccat
    11341 aacccggatg tctttctgcc ggatcatttt cttcaacgta ttccagtctt cccctgacag
    11401 gcgggaaagt ctgtccacat cctcgataag caaaatgtca ttttgctggc aatctctcag
    11461 aagacgaaaa agttccgggc gctcaagacg ggagccggat tcattctcaa tatagtagct
    11521 gcaaatgatc aggtctcttt ccctggcaaa agcctcgata gtttccaggg cacgcgaagc
    11581 atcctgttct gctgttgaag ctctcagata agcgcgaaca aagcttgttg gtacatttga
    11641 agtcatatta cagaaccggt tcacataagg tcacaccact atacccaaaa tgcaccagaa
    11701 agtagatcga caggaaaggc acactctaaa agaaccaaaa aacaaataat gagtagatgt
    11761 gaccttgtca ctatacactc ataaactcaa atgcccacac acacaaaaac ccatatgagt
    11821 aaacactctt taactcatat atacatagac tcatattaac ctttactcat acaaagagta
    11881 tggtaaactc aaaaactcac aggagtaatt gagtagacac acaattgagt atttaagtat
    11941 gaaagtgatc tcatttctga atccgaaagg gggttcaggt aaaacaactg ccgtaatcaa
    12001 catagccact gcgttgagca gaagcggata caacattgct gtggtagata cagatccaca
    12061 aatgagcctg acgaactgga gcaaagcagg caaagcagca tttgacgtat ttacagcagc
    12121 atcagaaaaa gacgtctatg gaattcgaaa agatctggcg gactatgact ttgctatcgt
    12181 ggacggggca ggttcactct cagtaatcac atccgcagcc gttatggtaa gcgacctggt
    12241 aattatccct gtcaccccca gccctctgga tttctccgca gcaggaagtg tggttacagt
    12301 cctggaagca caggcttaca gccgcaaagt agaagcccgc tttcttatca cccgtaagat
    12361 agaaatggca accatgttga atgtgcttaa agaaagtatc aaagacaccg gtgttaaagc
    12421 atttcgtaca gctattacac aacgtcaggt ttacgtgaaa tcgattcttg atggcgacag
    12481 cgtgtttgaa tccagtgatg gcgctgcaaa aggtgaaata gaaatcctta caaaagagat
    12541 agttagaata tttgagtaat tacacattta ctcatataat caaataagta taaaaacagg
    12601 agtagcctga atgtcacttg aaaaagcgca tacgtcagta aaaaaaatga cctttggtga
    12661 aaacagagat ctggaacgag tagtaacagc accagtatca tctggaaaaa tcaaacgtgt
    12721 taacgttaat tttgatgaag aaaagcacac ccggtttaag gctgcatgcg ccaggaaagg
    12781 tacatcaatt actgacgtgg tgaaccagct tgtagataac tggctcaaag agaacgaata
    12841 aaatttgagg aatatcatgg ataaaaaaat cgttgatgcg ctgagaacgc tattagaagc
    12901 gttacctgaa gaggtgataa cagaagtcac atcaaaacta aatccttcag caaaccatat
    12961 tcctgaagaa aacagtaagc aattgatagc aaaagcaaga gtactgaatt tccggctaac
    13021 cgaagtctat aaagaaatcc tggaagccga agcgagcaga acaagacaga gcaaaacaac
    13081 catccttaaa gcggcgctgg ccgctttcga tagcctggac gagaaccgga aaaaccattg
    13141 gctgcttgaa tctgcaaagt taggttagct cacagaagca ataaagcctt tacctgtgag
    13201 tatggaataa ggattgtcga gccgtcttac tgattgagga caggaaaggc aaaataataa
    13261 tgagaatatt catcgtatta gttggtcttt tattgggatg ctggaggtta tttgataact
    13321 acagatccta taaaaaagga atttataaag aacatcgcaa gatggctccg cctgtttatt
    13381 attatcgtgg agatcatacg tttgtcatac ggatagtaat tgattcactt ttgaccatag
    13441 tgatgattgg ttttgttgtc tggttctggt ttagaactgc ttaacagcat aatatcgagg
    13501 aagaaaaatt gcatcagatt atagatacag tattaacttc acgctatctg ttttggaaaa
    13561 aacagaagca agcaaattga taaaagagca tgaaaaacaa gaaaatatag aaccttatgg
    13621 ctatattttg cttataaaaa aggcagcatt gttagttctt tcatttgcag cattatttga
    13681 ttttataata cttttgtttg attactctag ccccaaaagc ccctgattat gtagaaagag
    13741 caaaatttct ttccatcctt acatttacac taatagctat atttatcggt ctgttatata
    13801 tatatgatta tttaatgaaa aaaataatga ggagtaacca ttcatcagaa ataaaagacc
    13861 aagaactaat gttacgtcta aaaataaatc gttcatacat tgaacaagtc atgaaaattg
    13921 gtagttcgag ggttttctgg aataacataa aaaagacata ccgaaagcaa ggatttctgt
    13981 ttatccagac aaaagaaaac agatgcatca tcatcccaga aagagtgttt aaaaatgaag
    14041 aagaaaccga aaaattatat aattttgtaa aagagaaaat agcacaaaac acaatggaat
    14101 gaaaaaggaa tattaagtaa tgatgaatat agtaaacaca atcgaattta tggtaaaaga
    14161 cattaataaa tatctggatg atatcactct gaacgccatc acagtggatg gcaaaactat
    14221 attaaaactt gaggatatgt ccaataaaaa tatatcccct cgccttgaaa agatactcag
    14281 aaagcttata aaaattgaag ttgaacatat acataacttt gatttcagta agctccagtc
    14341 tcttgaaaac tccaagagtt tcgaacatct tccagctaaa agtaaaaacc ctagttgcta
    14401 cagagacctg tattcgtggg gaaagggaat gcgtcacaca gaaaaactca gggcagaaga
    14461 cgagtccgac tggaaaaaga atatacaaca tatagaagaa gaaggattcc gtcgtaatag
    14521 gccaattgaa ataacatact acacatggct tgataggtat tttgtatcaa ataatggagg
    14581 ttctcatcac gcagcccttg ttgtctggca atcagttcga gacaaacttg aatacaaaag
    14641 ggaagccaat ataactaaac tcagcattga taaagtctcc ataaaaaaac tgaatagtga
    14701 ttactggtct tttatactaa acttcagata tcaaaccaac ataaatacat tatttaatct
    14761 gttcaatagc ctggtcagca agcatacaga catgctggaa ccaagtcatt atcatggcaa
    14821 ttacagattg ttttttgtcc ctaaaagcca gctaaagatg aacaagtatg cttttgaata
    14881 ctggtacaga aattctgtta aaaataaaaa gataattgca ctacctgagt acttagaaaa
    14941 cccacttcag tttcataccg ggggcattct catccagtag acagagaagg aacataagag
    15001 tcaatcctta aataacgcat ccagcttatc gctggtaagc aattctgcca gcgaattaca
    15061 tttcataaaa tcaatatcta tttcgttcag aacatcacaa taactgacat catcaaggct
    15121 aatgacaatc acaggaacat cggttttgag atcaaacact aaaagaggta ataaaatcga
    15181 gtttatcttt tcaaaatcac taaaaaattg ttcagagcca tactcaccgg caggaaaaag
    15241 aatctcactt aatctaacac cataaaaaac atgatagtgt tctttaagat tatcctttaa
    15301 aatattaaca gccttcgcat atttatcagt aataaatttt ctcacctgat atttcataaa
    15361 attctccaac aagaaccgac tgtaggtcac cgggcaaacg ttgcggaatg gcgtcagaga
    15421 cgtcattttg cggcgtttgc cctatcctgc atcgcagtga aaaggcaggg actggcataa
    15481 ctgctgagta gcatcattgc tggcttatct cgctactgtt ctcggtgctt tcgtccgcag
    15541 gttcgggaac aagtaacttg tgccagggca tagttttgtt gagcagctcc atcagaggct
    15601 cagccagcag tcccaaaatc caggttgccg taatcaccgg tatagtcaga ttttgtggcg
    15661 tccataactg gtgatcgaga tgataccagg tgatgacaca caaaatcccc cccagccaga
    15721 acacagccca tttaaacgca ccaagaatgg ctaacacaaa aacaaagata aaatgtaaaa
    15781 cactcgcggc aagaagacga agataaaacc atccccagcc aagccactta acaaaagtgc
    15841 tccctgtttt cactgcaaaa cgtttcttac gctccctggc gatttctttc ctgaatttag
    15901 ctcgttcttc cccctgaggg aattgataga ttttagccat gagttacctc atttcgatct
    15961 caaaacggac tttgctgact cttctcccct gcctttcagc attaacacat ttaatgtttt
    16021 taacatctgt cctttctgtt atttcatcaa tagctatatt gattccatct cttttaaaga
    16081 aagaaaactt ttgattttga atataaccta tttctttctt aagttcatct acacctatag
    16141 tgaaagattt aagatggcta aattttatca gttgatataa aggccatgag tatcttcctt
    16201 gaagagacaa agcagatttt agaggaagct cggtaacctg atatttacgg gagtctatcg
    16261 ctgtaatata atttatcgtc ttagacgaaa acataacacg aagcaatccc tcattcgaaa
    16321 tatagtcaca atgtgtaatt aaatttttat ttcttgaaaa gaaatctgct gcatccttca
    16381 tttgcttata tgcgacagaa cgctcaacac caacaaattc tgcatactta tcagcccgga
    16441 tcaatagcga cttatccgat tcaagtttat tttcaaagta ataatataaa caaataaaaa
    16501 agacccttct tgccgaaaat gacagttcat taactaacag atttaatccg ctattatatc
    16561 taatgatttt atcgtaatta acatgcctca tagtagatga aaaaagagaa ggacaagctt
    16621 tagtagctaa agctcctgat tctgtctttc ttcttatatg aagagtctca tttatttcta
    16681 gtacctccaa taaggttcca tcttcccatc ctgtattttc tatcatacta gcaggaatga
    16741 taattactgc cgcaccacct tgtttatgta attttatttg ctccatagtg tatttacctt
    16801 tatatattaa gcacctctga aaccatacgg tattctggta tcaagtcctt cgctttcttt
    16861 atctatttta tacgaaaatc ttagctttga tgctcttctt gcgactctct caacaatttt
    16921 aacttcgaga tgattaatct ctgtatattg atttattttt tcaatatttt tttgcagaaa
    16981 aaccttatta aaatccttaa aattctgata aaggtaaact ttttcgccat tatctattct
    17041 gaataattca agttcatcct ttaatacatc tacttcaatg tcgaaaaatg tctttttacc
    17101 actgctgtat tgtttcctga taaactgata aagcatattt gaattttgat cagcgagtct
    17161 tacagacgat atcaaaacct gagtagtgta agaatccttt aacatcgtga tatatggctc
    17221 aatgacatgt gaaaaagcaa tatcaatata tccttcactt tcaacataat cacaaaacgc
    17281 agtcaggttc ataagcctga ctgcatcaga aggtaattta cctctcttct tcgtatgtcc
    17341 agagctttga ttgccctgag ctgtgagaag ttgatttcga ggaatacgaa taacactggc
    17401 ctgaagttct tctgccccct ctttcaactg ccggtaagca cctgttacat caatatcagc
    17461 gataaatgca tattcccgag ccgtaatacg aaaggttgcc ccctcagata actcttcacg
    17521 tgaatcaatc tgcgccatag ccataaacaa aattcttctg gcagacaaag gcaacgatga
    17581 gaatgtgctg ttaatttcat ttctgtggcg aatttttgtt ttctttgtaa cgctcagtaa
    17641 gttcatacat tacctttggt ttttaagttc ttatggtgaa atcataacca caaaggcgga
    17701 aatatgtaaa gtggtttatc caccttatat gtttccacca aaacacggat cacatgaaag
    17761 aatttttatc atttatattc aatatgatag aaatgcgcag gtatccacct tttaacgtca
    17821 tacgttagat tagagcacta taaagaacta aagaaatgaa gatacaaaga tacgaatatc
    17881 tgaataaaaa cagaaaaatg cgtacccatc cacctttcag tgcgtaccca tccacctttc
    17941 agtgcgcagc catccacctt tcatgaaaat tacagtgcgt acccatccac ctttcagtgc
    18001 gtacccatcc acctttcatt ttgaggcgac aaaaaacaac acctatctta atgaaattat
    18061 tgataaaaaa actggcacaa tgtttgcaga ataagttaga gtaagttaaa gatcttaaag
    18121 tagatctacc gatctacatt taagatctta aaaacaagaa gtttaataag caaaaaaaca
    18181 caaaaaatct gtggataact ttgctcaaaa caaaaaattc acactacctg tggataactt
    18241 tgcgtaaacc cagaggacag atcactctga accaagacaa ccacacataa aaacaatatg
    18301 ctcgcttttt aaccactgcg cgtaattgcc tgatgttatc cctgtgctgt tccgcttcct
    18361 cgctcactaa ctcgctacac tcggtcgttc ggctgcggcg agcggtgtct cctttctcaa
    18421 aaccagaaga gttcagatca tacgatccgt tgattgatcc tttttggatc tttcactgag
    18481 aagccctgaa tcgctttcta acgctttgtt cgatgtaacc atgaggaaaa ccatgtgaaa
    18541 tcgaaaaaat cgctcagaat gcgatacagc gcgttttaga gggtatttac aaaacagtcg
    18601 ttgccttgag gaaattttga tcaagattga actcctatcc ggatcatggc aacagatcac
    18661 agcaacaagg ccgctaaaaa gcgttgagcg gcgttaaaaa ccgttaaacc gtagctgact
    18721 ataacgaaac gggaaaaaac gctcagaacg cgttacagag cgttttaagg cgatgtcgga
    18781 aagagccata cctcacctgt tctgatgttt ttctcagcac aagcactttt aagagtactt
    18841 ttaaagatgc tattatgcca ataagacaag cggaggactt atgagctatc aaattctgac
    18901 aaccacagcg gccagtatta ctgacctgaa aaaaaatcct atgggaaccg tagctgaagg
    18961 tgaaggggac gctgttgcga tcctgaaccg aaacgaaccg gcgttctatt gcgttccacc
    19021 aaaactttac gcctactatc gggaactcgc tgaagatgct gagttaaacg ctgttgctga
    19081 tgagcgcatg aaaaacccgg aaattgtgaa ggttaacctg gatgacctat gaactggctt
    19141 ttgaccgcag agcactgaag gaatggcaga aactcggcca caccatccgt gaacaattca
    19201 aaaagaagct ggcagaacgg ctggaaaatc cacgcgtacc cgcagcccgg ttacatggtc
    19261 atgctgatcg ctataaaatc aaacttcgtg catctggcta cagacttgta tatcaagtca
    19321 ttgatgagaa agtcgtttta ctcgttattg ctgttggaag aagggaaagc agcgaagttt
    19381 atcagattgc agatatgcgc tgaactgaaa cccgccccgt aattcgcggc tgcagccgct
    19441 cagacgcgca gatgctacac accgtcacgg cgtaccgttc gcaagcttac gcgctaactg
    19501 cgaaaggcta attgcgtgtt gttagtccgg taatgggctt tgcagggagg ggggatgtcc
    19561 ctgatcttaa ttaagctggt ttgtttccgg cgattcggga atggcaattc tattcggcgt
    19621 ctggtgtgtc gccttccatg ccctgacggg cataaaaaac ttgccatacc atcatatgat
    19681 ggtatgatga gtttgttggt tgggaatggt tccctgccag attccagcag cccaaacggg
    19741 cgggagcgaa aaatgaatat tcaggaagca ttaaacattt ttggtttatc cggcgatctg
    19801 actgaaaagg acatcaaggc ggcctacaga aaagcggctt taaaatatca tccagatcgt
    19861 aatccactgg gtgccgaact gatgaaagca gttaacgctg cgtttgattt tctcatggct
    19921 aacattgaca aaattaatca gtttcaaagc actgatgaaa acgcacgtta caactacggt
    19981 gaagatctgg aaaaagtttt gaatactctt tccggcctga ctggaattgt ctatgaagtt
    20041 attggtaatt gggtatggat tagtggtgaa accattactc ataaagaaac gttaaaagaa
    20101 atcgggtgta aatgggccgc aaagaaaaaa caatggtttt atcgtccgga agaacataaa
    20161 agttactgga accgtgaaga acacacgata gaggaaatcc gcgcaaaata tggttcgacc
    20221 ggacagcgca gggcgacggg atggcaacaa gtggaaacca gagcgtaacc agaagggggc
    20281 gaaagcccct tattattata aatatgttca ctaaataacg aaggtgtcag ttgggaggga
    20341 tatgcaaaac gataagtttt ttgaacggta tcaacccgtt tttgaaatcg tatgtcgaat
    20401 cctggggaac ggctggcgtg taaacctgct cgatgattgc cagtacagga taaaactaac
    20461 ctcgcctcag tataaaaatt actctataca tattcgaatg gagaagggaa ggttagttat
    20521 cattggaagc gtagatagtc gaagttggcg aagtccttac catacttgca ctgtatcgcc
    20581 agaacgtaac cctgtagaaa ttgccgccga tattgaaaag aaaatcctga cagatgcttt
    20641 cgaaaatgta gagaaggcaa tggaatatga aaggcagtta caaaaaaaac gggagcaaac
    20701 gcaaattctg aaaggaatgc tatctcgttt aatacgtctt gatagctggc atgggacatt
    20761 gaccggtttt aaagttgaga atgggttaga tggtaacgtg tcagaacggg gcggcggttt
    20821 tgaaatggta atacgtggcc tgagtgtgga tcagctcata aaggtagcgg ggtttattaa
    20881 acagctatga ggcaaaagat gaatgaagtc ctgagcgaca ggaaaaataa aggtaatgta
    20941 acatacagga ttgttgtgtc tgaagatgca acacgtttgt ttattgaact tgaaaaacta
    21001 atgaaagttc gctctaaaga agcggataaa aaaacaacta aaaaggttgt tttccataaa
    21061 tcattttatt atgaagaatt ctgtaacgtt aaagatgaaa ttgatgatcc aattttattg
    21121 caattctata cagatactat tgtgaaggta ctaaatcatg agttttaaac ccacacctga
    21181 agaggtgaaa caagctcgta tcaaagctgg ctttacgcag caggaagccg ctaaacggtt
    21241 tggtttttcg ttatcagcct ggcaggccaa agaaacatcc ggcaaaacat ctcgcggtct
    21301 agccgctggt acgtatgaat tacttttgct cctggctgat gaacatcccg attaccagct
    21361 agtaaagcga gaaaaaaatc agaataaaga gactaaataa attgcattac catcatttga
    21421 tggtataatt tgtttgtagg tcaggaatag ttccttacca tgatccagtg gcactgttgc
    21481 aaatagtcgg tggtgataaa cttatcatcc ccttttgctg atggagctgc acatgaaccc
    21541 attcaaaggc cggcattttc agcgtgacat cattctgtgg gccgtacgct ggtactgcaa
    21601 atacggcatc agttaccgtg agctgcagga gatgctggct gaacgcggag tgaatgtcga
    21661 tcactccacg atttaccgct gggttcagcg ttatgcgcct gaaatggaaa aacggctgcg
    21721 ctggtactgg cgtaaccctt ccgatctttg cccgtggcac atggatgaaa cctacgtgaa
    21781 ggtcaatggc cgctgggcgt atctgtaccg ggccgtcgac agccggggcc gcactgtcga
    21841 tttttatctc tcctcccgtc gtaacagcaa agctgcatac cggtttctgg gtaaaatcct
    21901 caacaacgtg aagaagtggc agatcccgcg attcatcaac acggataaag cgcccgccta
    21961 tggtcgcgcg cttgctctgc tcaaacgcga aggccggtgc ccgtctgacg ttgaacaccg
    22021 acagattaag taccggaaca acgtgattga atgcgatcat ggcaaactga aacggataat
    22081 cggcgccacg ctgggattta aatccatgaa gacggcttac gccaccatca aaggtattga
    22141 ggtgatgcgt gcactacgca aaggccaggc ctcagcattt tattatggtg atcccctggg
    22201 cgaaatgcgc ctggtaagca gagtttttga aatgtaaggc ctttgaataa gacaaaaggc
    22261 tgcctcatcg ctaactttgc aacagtgccg cgcgacgagc agcagcacca ggagcagaag
    22321 cacgtcgaga aaaagcaaca gcagatcgag cagcgcccac ggcgggccgc tcgcatcgga
    22381 taagtcgaaa aatccggcta aagtggccga gctgcacatc aggccgcgcg gttttcctcc
    22441 ctgatcgccg gcgcggtttc ttcctccctg aaccgcatgc agacttgccg cctcggacac
    22501 cccgaggcgg ttttttttcg cctcgctcga gcatcgccgc atccgacgat gccgagacga
    22561 ccaggccgcg cacgtcgagc tgcagcatcg ccattgccga cgatggcacc aggtcgccgg
    22621 cggtggccac cgacctcgag ctcgcatcgc cacatccgac gatgcgcgcc ggcgtcgacc
    22681 atcgccaggt ctgacgatgg cggccgccct gccctggatc tcgcatcgcc atttctggcg
    22741 atgagatcca cggagcggcc atttagaccc gccaataacg acccggccaa gataaatcgc
    22801 atgacggcct ttttggccgg gggtagcatg accggacact ttgcgtatgc ccaaaggagc
    22861 ccgcaagtat gcgcaggacg aagccagtag ccgcgccgat ggtggcgcgg gtctatctgc
    22921 gcgtcagcac cgacgcgcag gacttggaac gccaagaggc gatcactacg gccgcgaagg
    22981 ccgccggcta ctacgtcgcc ggcatctacc gtgagaaggc atccggcgca cgcgccgacc
    23041 ggcctgagct gctgcgcatg atcggcgacc tacagcccgg cgaggtggtc attgccgaga
    23101 agatcgaccg catcagccgc ctacctttgc ccgaggccga gcgcctggtg gcctcgatac
    23161 aggccaaagg cgcaagcctg gccgtccctg gcgtggtcga tctatccgac ctggcggccg
    23221 aggcccaggg cgtcgccaag atcgtgctgg aagccgtgca gatcatgctt tttcgcctgg
    23281 ccttgcagat ggcccgcgac gactacgagg acaggcgcga acgccagcgc caaggcattg
    23341 agttggcccg ccaggccggg cggtacaagg gccgccgtgc tgatccgaag cgccgcgccc
    23401 aagttgtcgc gctgcgcaag tccggctaca gcatcaacaa gaccgccgag ctggccgggt
    23461 acagtgcggc ccaggtgaaa cggatatggg ccgaggtcag ccaggccgaa gcgaagcagc
    23521 acggcgcgtt cgtggaggac gcattgacgg aagccgatgc cctggccgct gtcggccagg
    23581 atgagcgcca ggaggaaagg gcatgaagaa gccgaaccaa gacgacgagc cgtttttcat
    23641 caccgaggag attgcggccg aaatgatcgc cggcggctat gagttcgagc tgccgcccat
    23701 tccttgcacc atccgcctac gcgacgtgct ggagcgcatg accgatgctg agctagcatt
    23761 gcagccgggc gagatcgccg accaggagcg tgaacgctgc cggcgcaagc cgtgttcaac
    23821 ctcatgatct ggtcatggta tttttcatgg cactgagcct gatagttctt gcaaattgtt
    23881 gtcactaaag ggttttgtgt gcttgtttac aatcgagtgg gagtgacggg cactggctgg
    23941 caatgtctag caacggcagg catttcggct gagggtaaaa gaactttccg ctaagcgata
    24001 gactgtatgt aaacacagta ttgcaaggac gcggaacatg cctcatgtgg cggccaggac
    24061 ggccagccgg gatcgggata ctggtcgtta ccagagccac cgacccgagc aaacccttct
    24121 ctatcagatc gttgacgagt attacccggc attcgctgcg cttatggcag agcagggaaa
    24181 ggaattgccg ggctatgtgc aacgggaatt tgaagaattt ctccaatgcg ggcggctgga
    24241 gcatggcttt ctacgggttc gctgcgagtc ttgccacgcc gagcacctgg tcgctttcag
    24301 ctgtaagcgt cgcggtttct gcccgagctg tggggcgcgg cggatggccg aaagtgccgc
    24361 cttgctggtt gatgaagtac tgcctgaaca acccatgcgt cagtgggtgt tgagcttccc
    24421 gtttcagctg cgtttcctgt ttgccagccg gcccgagatc atggggtggg tgctgggcat
    24481 cgtttaccgc gtcattgcca cgcacctggt caagaaagcg ggccataccc accaagtggc
    24541 caagacgggc gcggtcaccc tgatccagcg ttttggatcg gcgctcaatc tgaatgttca
    24601 cttccacatg ctgtttctcg acggtgtgta tgtcgagcaa tcccacggct cagcgcgttt
    24661 ccgctgggtc aaggcgccga ccagcccaga gctcacccag ctgacgcaca ccatcgccca
    24721 ccgggtgggt cgctatctgg aacggcaagg cctgctggaa cgggaagctc aacacccact
    24781 gacgcatggg ttgttcaggc agtacttcat caaccagcaa ggcggcactt tcggccatcc
    24841 gccgcgcccc acagctcggg cagaaaccgc gacgcttaca gctgaaagcg accaggtgct
    24901 cggcgtggca agactcgcag cgaacccgta gaaagccatg ctccagccgc ccgcattgga
    24961 gaaattcttc aaattcccgt tgcacatagc ccggcaattc ctttccctgc tctgccataa
    25021 gcgcagcgaa tgccgggtaa tactcgtcaa cgatctgata gagaagggtt tgctcgggtc
    25081 ggtggctctg gtaacgacca gtatcccgat cccggctggc cgtcctggcc gccacatgag
    25141 gcatgttccg cgtccttgca atactgtgtt tacatacagt ctatcgctta gcggaaagtt
    25201 cttttaccct cagccgaaat gcctgccgtt gctagacatt gccagccagt gcccgtcact
    25261 ccgcggtctt cactgcgtga tcgagttgat cgacacccgc cgtgacacgc tccatgaagt
    25321 gcctgcctgc gtctgttagc cgaacgcccc gcgcatggcg ctcaaatagc aggacaccaa
    25381 ggttatcctc cagcgctttc acacgcgcgc tgacgctcga ctggctgata ccaagtgcct
    25441 tggccgcatg ccgaaaattc agatgctcgg cgacggcgat gaactgaaca agggaaatga
    25501 gcggtatcct gccagacagg ataccgacat tcacgaggtt tcgatggtta gtgcgccgca
    25561 tcggagcggg cctgctacca gtcgtcggtt agacgactgg cgacttctcg gtggcagccc
    25621 cacggagccg aaggagcacc agccccaacg aaaccagtac cgccatcgcc gtggcgtaac
    25681 agatcacggg ccacgctgtg tcaccgttta aaagtgccac cgccaatgtc ccgacaatgc
    25741 tgactatcag gctttgaacg cagaagtaga acgcgaccgc tgatcccgcg atgtcgtcga
    25801 actctgccaa agcgccgttc gcggtaacgg acaccgtgaa gacaataccg accgcgacaa
    25861 cccacatcgg taggatgaag gtgaggaatg acggcga
//
