LOCUS       NZ_CP066675            25974 bp    DNA     circular CON 20-FEB-2024
DEFINITION  Enterococcus faecium strain Dallas 163_1 plasmid p2, complete
            sequence.
ACCESSION   NZ_CP066675
VERSION     NZ_CP066675.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN17038111
            Assembly: GCF_016415485.1
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25974)
  AUTHORS   Islam,M.J. and Palmer,K.
  TITLE     Molecular characterization of VREfm isolates from Dallas, Texas
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 25974)
  AUTHORS   Islam,M.J. and Palmer,K.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-DEC-2020) Biological Sciences, University of Texas at
            Dallas, 1520 Richardson Dr Apt 1418, Richardson, TX 75080, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2019
            Assembly Method                   :: Unicycler v. 0.4.7
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 137.0x
            Sequencing Technology :: Illumina NextSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/20/2024 02:34:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,080
            CDSs (total)                      :: 2,989
            Genes (coding)                    :: 2,842
            CDSs (with protein)               :: 2,842
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 53 of 147
            Pseudo Genes (incomplete)         :: 94 of 147
            Pseudo Genes (internal stop)      :: 38 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP066675.1.
            Bacteria and source DNA available from Dr. Kelli Palmer, UTDallas.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..25974
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /strain="Dallas 163_1"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /plasmid="p2"
                     /geo_loc_name="USA: Dallas"
                     /collection_date="2015"
     gene            1..1041
                     /locus_tag="JCP82_RS14850"
                     /old_locus_tag="JCP82_14850"
     CDS             1..1041
                     /locus_tag="JCP82_RS14850"
                     /old_locus_tag="JCP82_14850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_000997689.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLLK
                     DRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGRVN
                     KRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTTVIA
                     KIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVDIMKE
                     DSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELESYGIDA
                     DKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFNELPTVS
                     TENWLE"
                     /name="replication initiator protein A"
     gene            complement(1657..2337)
                     /locus_tag="JCP82_RS14855"
                     /old_locus_tag="JCP82_14855"
     CDS             complement(1657..2337)
                     /locus_tag="JCP82_RS14855"
                     /old_locus_tag="JCP82_14855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_002287920.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIGADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            2483..2566
                     /locus_tag="JCP82_RS14860"
                     /old_locus_tag="JCP82_14860"
     CDS             2483..2566
                     /locus_tag="JCP82_RS14860"
                     /old_locus_tag="JCP82_14860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]; GO:0031556 - transcriptional attenuation by ribosome
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="WP_001814874.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
                     /name="23S rRNA methyltransferase attenuation leader
                     peptide"
     gene            2691..>3017
                     /locus_tag="JCP82_RS14865"
                     /old_locus_tag="JCP82_14865"
                     /pseudo=""
     CDS             2691..>3017
                     /locus_tag="JCP82_RS14865"
                     /old_locus_tag="JCP82_14865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA adenine N-6-methyltransferase family
                     protein"
                     /name="rRNA adenine N-6-methyltransferase family protein"
     gene            complement(3179..4327)
                     /gene="tnpB"
                     /locus_tag="JCP82_RS14870"
                     /old_locus_tag="JCP82_14870"
     CDS             complement(3179..4327)
                     /gene="tnpB"
                     /locus_tag="JCP82_RS14870"
                     /old_locus_tag="JCP82_14870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element RNA-guided
                     endonuclease TnpB"
                     /protein_id="WP_002287525.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYEE
                     VKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRFKS
                     KKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSSGKY
                     YISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQRKLS
                     RRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDIICIED
                     LNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICSECGHKD
                     GKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
                     /name="tnpB"
     gene            complement(4344..4748)
                     /gene="tnpA"
                     /locus_tag="JCP82_RS14875"
                     /old_locus_tag="JCP82_14875"
     CDS             complement(4344..4748)
                     /gene="tnpA"
                     /locus_tag="JCP82_RS14875"
                     /old_locus_tag="JCP82_14875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="WP_002287522.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERISE
                     SYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKEMF
                     WSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
                     /name="tnpA"
     gene            <4909..5319
                     /locus_tag="JCP82_RS14880"
                     /old_locus_tag="JCP82_14880"
                     /pseudo=""
     CDS             <4909..5319
                     /locus_tag="JCP82_RS14880"
                     /old_locus_tag="JCP82_14880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA adenine N-6-methyltransferase family
                     protein"
                     /name="rRNA adenine N-6-methyltransferase family protein"
     gene            <5489..5749
                     /locus_tag="JCP82_RS14885"
                     /old_locus_tag="JCP82_14885"
                     /pseudo=""
     CDS             <5489..5749
                     /locus_tag="JCP82_RS14885"
                     /old_locus_tag="JCP82_14885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /GO_component="GO:0005694 - chromosome [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
                     /name="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            5912..>6577
                     /locus_tag="JCP82_RS14890"
                     /old_locus_tag="JCP82_14890"
                     /pseudo=""
     CDS             5912..>6577
                     /locus_tag="JCP82_RS14890"
                     /old_locus_tag="JCP82_14890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
                     /name="IS1182-like element IS1182 family transposase"
     gene            6613..6858
                     /locus_tag="JCP82_RS14895"
                     /old_locus_tag="JCP82_14895"
     CDS             6613..6858
                     /locus_tag="JCP82_RS14895"
                     /old_locus_tag="JCP82_14895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="WP_000567888.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRLL
                     LGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
                     /name="single-stranded DNA-binding protein"
     gene            6961..7830
                     /locus_tag="JCP82_RS14900"
                     /old_locus_tag="JCP82_14900"
     CDS             6961..7830
                     /locus_tag="JCP82_RS14900"
                     /old_locus_tag="JCP82_14900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing protein"
                     /protein_id="WP_000228166.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIYY
                     NSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIKRV
                     EQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETYPNA
                     LQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYCINEK
                     KAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINNFLNEE
                     SSDERKQI"
                     /name="nucleotidyltransferase domain-containing protein"
     gene            7811..8545
                     /locus_tag="JCP82_RS14905"
                     /old_locus_tag="JCP82_14905"
     CDS             7811..8545
                     /locus_tag="JCP82_RS14905"
                     /old_locus_tag="JCP82_14905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]; GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_000662263.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGKR
                     VLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDFPE
                     ESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNEKGE
                     ILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPENMMD
                     IPGMADEMRRPMMLIVSAKKKM"
                     /name="class I SAM-dependent methyltransferase"
     gene            8578..9486
                     /locus_tag="JCP82_RS14910"
                     /old_locus_tag="JCP82_14910"
     CDS             8578..9486
                     /locus_tag="JCP82_RS14910"
                     /old_locus_tag="JCP82_14910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="WP_001255866.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYDI
                     TYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLTLL
                     PLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNVTPY
                     VIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYISEDLW
                     EKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRDMYKKY
                     TGKTGCLDSTYAADIEERREQ"
                     /name="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
     gene            9483..10025
                     /gene="sat4"
                     /locus_tag="JCP82_RS14915"
                     /old_locus_tag="JCP82_14915"
     ARG             9484..10022
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            10118..10912
                     /gene="aph(3')-IIIa"
                     /locus_tag="JCP82_RS14920"
                     /old_locus_tag="JCP82_14920"
     ARG             10119..10909
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(11055..12347)
                     /locus_tag="JCP82_RS14925"
                     /old_locus_tag="JCP82_14925"
     CDS             complement(11055..12347)
                     /locus_tag="JCP82_RS14925"
                     /old_locus_tag="JCP82_14925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1251 family transposase"
                     /protein_id="WP_000122610.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIYT
                     AQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADTSV
                     AKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTPLPK
                     VLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREAVEWI
                     VIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQKHYQLG
                     KQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQLYQDFL
                     YAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPLECLNNHI
                     KVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
                     /name="ISL3-like element IS1251 family transposase"
     gene            12695..13237
                     /locus_tag="JCP82_RS14930"
                     /old_locus_tag="JCP82_14930"
     CDS             12695..13237
                     /locus_tag="JCP82_RS14930"
                     /old_locus_tag="JCP82_14930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="WP_002321977.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLEE
                     AGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAMYK
                     IKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPASGG
                     QEPESRMIEPVLLQSFK"
                     /name="HTH domain-containing protein"
     gene            complement(13267..13947)
                     /locus_tag="JCP82_RS14935"
                     /old_locus_tag="JCP82_14935"
     CDS             complement(13267..13947)
                     /locus_tag="JCP82_RS14935"
                     /old_locus_tag="JCP82_14935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(<14023..14115)
                     /locus_tag="JCP82_RS15490"
                     /pseudo=""
     CDS             complement(<14023..14115)
                     /locus_tag="JCP82_RS15490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /name="replication initiation protein"
     gene            15242..15436
                     /locus_tag="JCP82_RS14940"
                     /old_locus_tag="JCP82_14940"
     CDS             15242..15436
                     /locus_tag="JCP82_RS14940"
                     /old_locus_tag="JCP82_14940"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_198995318.1"
                     /translation="MKTSNRKYKVKTVNHRIPPKKALCVINNSKVINQELKPYLSEQEM
                     IKKISKDIFLTNSGSVAKF"
                     /name="hypothetical protein"
     gene            complement(15470..16150)
                     /locus_tag="JCP82_RS14945"
                     /old_locus_tag="JCP82_14945"
     CDS             complement(15470..16150)
                     /locus_tag="JCP82_RS14945"
                     /old_locus_tag="JCP82_14945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(16663..17343)
                     /locus_tag="JCP82_RS14950"
                     /old_locus_tag="JCP82_14950"
     CDS             complement(16663..17343)
                     /locus_tag="JCP82_RS14950"
                     /old_locus_tag="JCP82_14950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_002287920.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIGADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            <17419..17985
                     /locus_tag="JCP82_RS14955"
                     /old_locus_tag="JCP82_14955"
                     /pseudo=""
     CDS             <17419..17985
                     /locus_tag="JCP82_RS14955"
                     /old_locus_tag="JCP82_14955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            complement(18032..18268)
                     /locus_tag="JCP82_RS15640"
     CDS             complement(18032..18268)
                     /locus_tag="JCP82_RS15640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_306297428.1"
                     /translation="MKQNTSIAKNTTKFKCTAAAWRISISPTNRTNNRGMILFIWISFF
                     LLGYRVLPAYFAPPKRRGRLERLVRNKNHSLSY"
                     /name="hypothetical protein"
     gene            18366..18545
                     /locus_tag="JCP82_RS14960"
                     /old_locus_tag="JCP82_14960"
     CDS             18366..18545
                     /locus_tag="JCP82_RS14960"
                     /old_locus_tag="JCP82_14960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001120991.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLLI
                     AQEKAGFEVPALKK"
                     /name="hypothetical protein"
     gene            18676..18945
                     /locus_tag="JCP82_RS14965"
                     /old_locus_tag="JCP82_14965"
     CDS             18676..18945
                     /locus_tag="JCP82_RS14965"
                     /old_locus_tag="JCP82_14965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /GO_component="GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="WP_000388479.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKRD
                     YDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
                     /name="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
     gene            18938..19195
                     /locus_tag="JCP82_RS14970"
                     /old_locus_tag="JCP82_14970"
     CDS             18938..19195
                     /locus_tag="JCP82_RS14970"
                     /old_locus_tag="JCP82_14970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /GO_process="GO:0008219 - cell death [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="WP_000588503.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLGK
                     PEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
                     /name="Txe/YoeB family addiction module toxin"
     gene            19654..20658
                     /locus_tag="JCP82_RS14975"
                     /old_locus_tag="JCP82_14975"
     CDS             19654..20658
                     /locus_tag="JCP82_RS14975"
                     /old_locus_tag="JCP82_14975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000455809.1"
                     /translation="MEYKFNLNLKEVLPTQGTININGQDNDDDIVIKKIEFIDSDINVF
                     FYSKEKLADFSNIAEMIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACEI
                     GVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRNKL
                     VHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNKSQITL
                     SKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD"
                     /name="hypothetical protein"
     gene            complement(20823..21437)
                     /locus_tag="JCP82_RS14980"
                     /old_locus_tag="JCP82_14980"
     CDS             complement(20823..21437)
                     /locus_tag="JCP82_RS14980"
                     /old_locus_tag="JCP82_14980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001261742.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRPV
                     FQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGNPL
                     LDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQRRL
                     VYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
                     /name="recombinase family protein"
     gene            21887..23212
                     /locus_tag="JCP82_RS14985"
                     /old_locus_tag="JCP82_14985"
     CDS             21887..23212
                     /locus_tag="JCP82_RS14985"
                     /old_locus_tag="JCP82_14985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="WP_000969590.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRAD
                     NTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNIFR
                     RYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIATVG
                     VGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRLNQMG
                     IMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQVLPRD
                     YTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKIPITDNT
                     KELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEENLDKIIDK
                     IRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
                     /name="Y-family DNA polymerase"
     gene            23205..23555
                     /locus_tag="JCP82_RS14990"
                     /old_locus_tag="JCP82_14990"
     CDS             23205..23555
                     /locus_tag="JCP82_RS14990"
                     /old_locus_tag="JCP82_14990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000568378.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTEE
                     IAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIRHI
                     EFYQDNKWSRLE"
                     /name="hypothetical protein"
     gene            23552..23731
                     /locus_tag="JCP82_RS14995"
                     /old_locus_tag="JCP82_14995"
     CDS             23552..23731
                     /locus_tag="JCP82_RS14995"
                     /old_locus_tag="JCP82_14995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001021554.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAAA
                     GYHNFRFYIFPLYI"
                     /name="hypothetical protein"
     gene            23867..24157
                     /locus_tag="JCP82_RS15000"
                     /old_locus_tag="JCP82_15000"
     CDS             23867..24157
                     /locus_tag="JCP82_RS15000"
                     /old_locus_tag="JCP82_15000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000026576.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITRQ
                     RRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
                     /name="hypothetical protein"
     gene            24525..25313
                     /locus_tag="JCP82_RS15005"
                     /old_locus_tag="JCP82_15005"
     CDS             24525..25313
                     /locus_tag="JCP82_RS15005"
                     /old_locus_tag="JCP82_15005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302898.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA]"
                     /GO_process="GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000101106.1"
                     /translation="MARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVDIDPQGN
                     ATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAEREFTQVGSE
                     HRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLKGLIKLSET
                     IETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKTYIRRTITVD
                     EAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
                     /name="AAA family ATPase"
     gene            25300..25626
                     /locus_tag="JCP82_RS15010"
                     /old_locus_tag="JCP82_15010"
     CDS             25300..25626
                     /locus_tag="JCP82_RS15010"
                     /old_locus_tag="JCP82_15010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000796719.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKDQ
                     GSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLAKK
                     QNKI"
                     /name="hypothetical protein"
     ARG             8579..9483
                     /name="ant(6)-Ia"
                     /gene="ant(6)-Ia"
                     /gene_name="aminoglycoside nucleotidyltransferase
                     ANT(6)-Ia"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             4820..5319
                     /name="ErmB"
                     /gene="ErmB"
                     /gene_name="Erm 23S ribosomal RNA methyltransferase"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; lincosamide antibiotic;
                     streptogramin antibiotic; streptogramin A antibiotic;
                     streptogramin B antibiotic"
                     /identity="97.79"
                     /coverage="66.94"
     ARG             2692..3038
                     /name="ErmB"
                     /gene="ErmB"
                     /gene_name="Erm 23S ribosomal RNA methyltransferase"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; lincosamide antibiotic;
                     streptogramin antibiotic; streptogramin A antibiotic;
                     streptogramin B antibiotic"
                     /identity="98.17"
                     /coverage="46.37"
     ARG             9484..10025
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="99.44"
                     /coverage="100.0"
     ARG             8579..9486
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="100.0"
                     /coverage="109.42"
     Typing          2..1041
                     /name="rep_cluster_889"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atgaatgatt ttaattatta caaatcaaaa gaaatttatc gtgaaaaata ttatcaaatg
       61 cctaaggtat tttttactaa cgaaaaatac atggatctat caaatgatgc aaaaattgct
      121 tatatgctac ttaaagatcg atttgattat tcagtcaaaa ataactgggt agattctgat
      181 gataatatat ttttcatatt cacagttgaa gaattaatga aattgttaca atgccgcgaa
      241 ggtaaagtat ctaaaatcaa aaaggaatta gaaaaagcag gtcttctgaa acagaagaga
      301 ggaagagtaa ataaacgtga cggtaagatt gaatccatgc ctaatttatt gtacttaggc
      361 aagccagaag taacgaatca agacgtcttt aaaatcatgg aagaggaaga caatactgat
      421 accaccgtaa ttgcgaaaat cgcaaatacg gcaaaaccgc gagaaatcaa tgataccacc
      481 gtaattgcga aaatcgcaaa tacggcaaaa tccagtcata tcaaggactc aaccgtaatt
      541 gcgaaaatcg cagacaatct attctattct aattctatag acactaatag acacataata
      601 gacactgaaa ctgatcagtt acaaaatcaa gttttactag ataacttcgt cgacatcatg
      661 aaagaggaca gtataaatac atttgtacca gaaaatgtat taaacttgat aaaaacattt
      721 tctagtactt acgaagacgc tcaaaaaacc gtccaaacta ttcataatgc aaagaaaaaa
      781 gctgaagaat tagagcaaac agttgttgtt tatgaagaac tggaatctta tggaattgat
      841 gctgacaaag gattatatat gactttgctg aaagcttatc aaaaacaaaa aactgaaaaa
      901 gtaaacaatt tgcagaatct aattttcgtt tatgtaaaaa attggtttgt cgaaaaagct
      961 attgcggcaa agcttgcaaa cgaacaaaga gaaacattta acgaattacc aacagttagt
     1021 acggaaaatt ggctagagta gttgataaaa agcgatcact ataaaaatga tcaattttaa
     1081 attagaactt ttttatgatt ttaattttat tacaaatgtt acaaataaat agctattatt
     1141 ccggagtttt tagattaaaa gtttatgaaa acaatcacaa acgtaggttt taaagtcata
     1201 atcgttagat attttagtta tttttcattc aaaaaaatag ggaactagtg tttgcatatg
     1261 tgcttttttg agttataata attcatgaag agaggtaatt cacttatttc cccaagctga
     1321 aaagcctgat attacttctt ttcaggcagt gctgctaata ttcaattaca cttttttgta
     1381 tatttttagt tgttttaaat ttaattgtct gatatgcttg tgatgaattg attttcgttc
     1441 tgcacttttg gacgataaat tgtgataatt gaaaatacaa aaaaaagaaa ggcccctgta
     1501 aggctcggga gactggtaat ctccgtcagt gtcctacagg aaagcattaa gatgacgcct
     1561 taatgcgtgc ccttcagtgt tacggtatta cccgcaacgg acggttctgt tgcaaagttt
     1621 taaataaaga ataaaatccc ttacggtatc tatgatttaa gctgggattc ccaataatac
     1681 cttgatttca gtacagaccg aaaacccgaa gagagtgcct tcttttcggg ttttcttata
     1741 taatcctcga atggcttcca tgcctttaat cgtggtagag gcagtgcgta aacttcgata
     1801 gaatttattg cgtctcttta ctggacgatg gtcttgttca atcaaattat tcaggtattt
     1861 aatggtacga tgttctgtcc cttgataaaa gccgtattct tttagtttct taaaggcact
     1921 tgtaatagag ggggctttat ctgtgactac aaccttcggt tcatcaaact gcttcactaa
     1981 ccgcttaaga aaagcatagg ctgcttgtgt gtcccgtttt ttacgtaacc aaatatccaa
     2041 ggttaaacca tctgcaccga tggctcgata caaataatgc cattttcctt taattttgat
     2101 gtacgtttca tccattttcc atgaataaaa ggatttttta tttttctttt tccaaatttg
     2161 atagagtagt ttgccatatt cttgcaccca acgataaatc gtcgtatgag aaacgttaat
     2221 gccacgatca tataagattt cttgaacttc acgatagcta aggttataac gaagatagta
     2281 gcccacggct acaataatca catcctgctg aaattgcttt cctttaaaat gattcatcgt
     2341 cattcctcct gctatctttt tctattattc taccttattt gatagtagat ttaaaacttt
     2401 gcaacagaac cattttgtgt ataataggaa ttgaagttaa attagatgct aaaaatttgt
     2461 aattaagaag gagggattcg tcatgttggt attccaaatg cgtaatgtag ataaaacatc
     2521 tactgttttg aaacagacta aaaacagtga ttacgcagat aaataaatac gttagattaa
     2581 ttcctaccag tgactaatct tatgactttt taaacagata actaaaatta caaacaaatc
     2641 gtttaacttc tgtatttatt tacagatgta ataacttcag gagtgattac atgaacaaaa
     2701 atataaaata ttctcaaaac tttttaacga gtgaaaaagt actcaaccaa ataataaaac
     2761 aattgaattt aaaagaaacc gataccgttt acgaaattgg aacaggtaaa gggcatttaa
     2821 cgacgaaact ggctaaaata agtaaacagg taacgtctat tgaattagac agtcatctat
     2881 tcaacttatc gtcagaaaaa ttaaaactga acattcgtgt cactttaatt caccaagata
     2941 ttctacagtt tcaattccct aacaaacaga ggtataaaat tgttgggagt attccttacc
     3001 atttaagcac acaaattagt gaactactca ccacttagct aaacctgacg gttcttaacg
     3061 cttgaagtgg gagcttcttg ggaatagagc atacttgata gcgtatttct ttactaacag
     3121 cggtgtctct tatttaccaa gctatccccg tagttcctac ggttcttgat gattggatct
     3181 aagccaatcc catagaatgt agtcttagac cttcggtcag aatattgata ctagcattga
     3241 tatcacgatc atgatgagta tgacaaacag gacaagtcca ttctcgaatt tcaagagatt
     3301 tcttgccatc tttatgtccg cactctgaac aaatctgact agacggaaac catttatcta
     3361 ctttgatgat ttttcgtcca taccagtcag ccttgtattg taatttagtc acaaactttg
     3421 accaagaaac atcagaaata cttttagcta atttatgatt tcgcaacata ccttttgtgt
     3481 ttaagtcttc aatacagata atatcgtgat ttttgatcat ttctgtactc aacttattca
     3541 gaaaatcagt acgttgattc attacttttt catgcaatct agctactttg cgtttttgtt
     3601 tttgataatt tttagcttca aatagattgg tacctttatt tttagccaat aaagcacgcc
     3661 tagacaattt gcgttgttca cgctttagtt tcttttccat tttggacgtg aatttattat
     3721 tatcaatttt ttgtccatca gaaagaatcg caaagtccat aatacctaag tcaataccaa
     3781 ttgtggaatt agttttaggt aattcgataa tttcttcttt acacaacaaa gaaatatagt
     3841 atttaccgct agaatgacgt gatattgtag cagatttgat aatccctttt ggttgtctat
     3901 gaagcttaat tcttactaat gacttcaatt taggaacttt gatgaattta ctatcaatca
     3961 aagcaactgt accattttga ttattcgttg tataactctg aacaggattt ttcttacttt
     4021 tgaaacgtgg aaatccaacg gatttatccc gaaaaaaatt cttgtatgct ttatctaaat
     4081 taagttgggc attggctaaa gcaaggctat caatttcttt caaaaacgga aattctttct
     4141 tgtatttagc tggtgtcgga aaagtcattt ttttagaaga atcattttta acttcttcat
     4201 acgccttttt tcggtcatca agcattagat tgtagacctt acggacacaa ccaaaagatt
     4261 tggcaaagaa gatttcttgt tcctctgttg gatagattct gaatttgtat gcttttagtt
     4321 gttccataaa gttcacctac tttctattta tgattgtttc cttgattttg gatatacttc
     4381 ttaatcacat caattggtgc gccaccagtt gtcagaagac aaaaactttt agaccagaac
     4441 atttctttcc aaagaaattg tttgactctt ggaaagtcac gttttatcaa tcttgagctg
     4501 gcacttttat aggcattgat gaattttgtc aattctgttt taggttgagc tttgaacata
     4561 atatgaacgt ggtctttatc atgattccac tccactaaag taatgtgata cgattctgaa
     4621 attctttcaa aagtagtttt ggcataatca gatatttcat catcaatcac ttgtctacga
     4681 tatttcgtta ctaaaacaag gtggtaataa agaagaaata ctgaatgatt atttgtatct
     4741 aattccatgt tatatcaact catttcttgt atagactgat tgtaacatgg aacaaaataa
     4801 aaaggcaata cgccttagtt gtcggtcttc gagttaccaa cggtaaccct cataccgaac
     4861 ggcattcatc acccacctat agaggatggg cgacttctgc ctaattctgt taaaaaagtg
     4921 gtttttgaaa gccatgcgtc tgacatctat ctgattgttg aagaaggatt ctacaagcgt
     4981 accttggata ttcaccgaac actagggttg ctcttgcaca ctcaagtctc gattcagcaa
     5041 ttgcttaagc tgccagcgga atgctttcat cctaaaccaa aagtaaacag tgtcttaata
     5101 aaacttaccc gccataccac agatgttcca gataaatatt ggaagctata tacgtacttt
     5161 gtttcaaaat gggtcaatcg agaatatcgt caactgttta ctaaaaatca gtttcatcaa
     5221 gcaatgaaac acgccaaagt aaacaattta agtaccgtta cttatgagca agtattgtct
     5281 atttttaata gttatctatt atttaacggg aggaaataat tctatgagtc gcttttttaa
     5341 atttggaaag ttacacgtta ctaaagggaa tggagataaa ttattagata tactactgac
     5401 agcttccaag aagctaaaga ggtccctagc gcctacgggg aatttgtatc gataaggggt
     5461 acaaattccc actaagcgct cgggacccct tgtaggaaaa tgtcctaagt gtggcaacaa
     5521 tattgtatta aaaaaatcgt tttatggttg ttcaaattat cctgaatgta agtttacttt
     5581 agctgaacat tttagaaaga aaaaactaac caaaacgaat gtaaaagaat tactggaggg
     5641 aaaagaaacc ctggtaaaag gaatcaaaaa caaagagaaa aagccctaca atgccgttgt
     5701 aaaaattggg gaaaagggat atattgattt tatctctttt tcaaaataaa catggggctg
     5761 acccaaaagt agctcctata tgaaaaatag aggtctttcc atttagatag tagtggaaag
     5821 acctctattt atcttttgaa agtgaataca aaaataaagc acactctgct ataatatagg
     5881 tgattaatcc atttgagaga ggtgctttat catgtatcaa aattatacca taaaccaact
     5941 ttgtttgcct atagatcttg aaattaaatt agaagaaaat gattttgctc atgccattgt
     6001 gcagtttgtt gactctattc ccgatgaagt ctttcttcct tattatcaat ctatgggtag
     6061 accccaatat catcctcgta tgctactttc cattattctt tgtgcctata ttcaaggggt
     6121 ttattcgggc cgccaaatac aaaatatgct gatagatagt attcggatgc gctacttatc
     6181 tcaagagcaa ttccctaact ttcgtactat taatcgtttt cgcgttcatc cgattatgaa
     6241 cgatattcta gatcattcat ttgttcaatt tcgtgagcta ctggttcaaa gtggcttaat
     6301 cagtggcagt gctctataca ttgatggtac aaaaattgaa gcggatgcga ataaatactc
     6361 tttcgtttgg aaaaaaagta ttttaaagta taaggatagc cttgatcaaa aagcccttga
     6421 aaactaccaa caaatggtgg aaacaaaaat cttacctgag ttaatagatg atttaaagga
     6481 tgaactttct atagaagaga ttgaaaggat tcgtcaatct ttggaagaaa aggaaaatca
     6541 attaattgaa gcgattgacc aaaccgaaac agtagaaggg ggctgaccca ttattaataa
     6601 ggagtggaca acatgattga tgtaaatgag ctattggaag aagctattag agaaactgaa
     6661 aatctaaatg atggcgaagt ttttcttgtt aaagatttat tcaagggata tgtggggaat
     6721 aggataccca gaaaggatcg acttctgctt ggaacgttat ttttaaacca tgttagcaaa
     6781 atgaatggta atttaaaggc tattgaaaag acttcatcta atcagcagag gtataaaaag
     6841 acaattgata agttttaact atcttttgtg aaattaaaaa aattataaat atgttgagta
     6901 gaagcaaaag atttggcttg gaatttttac agcagtgaat cgataaaagg agcatgcttg
     6961 atggtagata atattattaa atcagtagca gagaaattat cctctctgtc ttatatagaa
     7021 ggtattgttt taggtggttc acgtgcaagg ggcacccata cagaggattc ggatatagat
     7081 atcggcatct attacaattc agaatcattt gacataaata ctattaatca attcgctaca
     7141 aagctggatg atgagcatag aaataacctt gttgtacctc ccggagcatg gggtgattgg
     7201 attaatggcg gcggatggtt agtcataaac gggtatcatg tggatttaat tttacgtgat
     7261 attaaacgtg tggaacaaat aatgaaagat acagagcacg gaattgttac tgccaattat
     7321 cagactgggc atccccatgg ttatattagt gcaatgtatc gaggagaatt agcgattagc
     7381 aaaatactat atgctaagaa tgaaagctta tgcgaattaa aaaaacaggc agaaacttat
     7441 cccaatgctt tgcagaaaag tttagttaac ttttttatgt ttgaagcagg gttctcttta
     7501 atgtttgtaa aagcaaattc gggaacagac gataaatatt atattgcggg tcatgttttt
     7561 cgtatagttt catgtttaaa tcaagtgtta tttgcatgta ataatgctta ttgtatcaac
     7621 gaaaagaaag ctataaaact gcttgaaact tttgaacata aacctgaaaa atataccgag
     7681 aaggtaaatc atatttttga agtactcggt atctcacttt ttgaatgcta cgacatgacc
     7741 gagaagcttt ataatgaagt gaatgaaatt gtatcggaga taaataactt tttaaacgag
     7801 gagagttcag atgaaagaaa acaaatatga tgataatata ttttttcaaa aatacagtca
     7861 aatgagtcgc tcgcagaaag gactggctgg tgcgggagaa tgggagactt tgaaaaagat
     7921 gctacctgat tttaagggta agcgtgtgct tgatttagga tgcggctatg gatggcactg
     7981 tatatatgcg atggaaaacg gtgcttcctc tgtagtaggt gttgatattt ctcataaaat
     8041 gctcgaagta gcaaaaggaa aaacccattt tccacagatt gaatatgaat gctgtgccat
     8101 agaagatgtg gatttcccag aggagagctt tgatgtaata ctaagttcgc ttgcgtttca
     8161 ttatgtagca gactatgaga atttaataaa aaagatatat aggatgctga aggctggtgg
     8221 caatttagtt tttacagttg aacatcctgt ttttactgct catggaacac aagactggta
     8281 ttataacgaa aaaggagaaa tactgcattt cccggtggac aattattatt atgagggcaa
     8341 acggacagct atgtttttgg aagaaaaggt tacaaaatat catagaacac tgaccacata
     8401 tctaaataca ctgctttcaa atagttttat aataaatcag attgtggagc cacagccgcc
     8461 agagaacatg atggatattc cggggatggc ggatgaaatg cgacgcccaa tgatgctgat
     8521 tgtatcggca aaaaagaaga tgtaataata tagaaaaaat aaacgaggag tatgtaaatg
     8581 agatcagaaa aagaaatgat ggatttagta ctttctttag cagaacagga tgaacgtatt
     8641 cgaattgtga cccttgaggg gtcacgcgca aatattaata tacctaaaga tgaatttcag
     8701 gattatgata ttacatattt tgtaagtgat atagaaccgt ttatatctaa tgatgactgg
     8761 cttaatcaat ttgggaatat aataatgatg caaaagccgg aggatatgga attattccca
     8821 cctgaagaaa agggattttc ctatcttatg ctatttgatg attacaataa aattgatctt
     8881 accttattgc ccttggaaga gttagataat tacctaaagg gcgataaatt aataaaggtt
     8941 ctaattgata aagattgtag aattaaaagg gacatagttc cgactgatat agattatcat
     9001 gtaagaaagc caagcgcaag ggagtatgat gattgctgca atgaattttg gaatgtaaca
     9061 ccttatgtta ttaaaggatt gtgccgtaag gaaattttat ttgctattga tcattttaat
     9121 cagattgttc gccatgagct gctgagaatg atatcatgga aggtcggcat cgaaacaggc
     9181 tttaaattaa gtgtaggcaa gaactataag tttattgaaa ggtatatatc cgaggatttg
     9241 tgggagaaac ttttgtccac ctaccggatg gattcctatg aaaacatatg ggaagcatta
     9301 tttctatgcc atcaattgtt cagggcggta tccggtgagg tggcggaaag gcttcattat
     9361 gcctatccgg agtatgatag gaatataaca aaatatacca gggacatgta taaaaaatac
     9421 actggtaaaa ccggctgcct ggatagcaca tatgccgctg atatagaaga gaggcgggaa
     9481 cagtgattac agaaatgaaa gcagggcacc tgaaagatat cgataaaccc agcgaaccat
     9541 ttgaggtgat aggtaagatt ataccgaggt atgaaaacga gaattggacc tttacagaat
     9601 tactctatga agcgccatat ttaaaaagct accaagacga agaggatgaa gaggatgagg
     9661 aggcagattg ccttgaatat attgacaata ctgataagat aatatatctt tactaccaag
     9721 acgataaatg cgtcggaaaa gttaaactgc gaaaaaattg gaaccggtac gcttatatag
     9781 aagatatcgc cgtatgtaag gatttcaggg ggcaaggcat aggcagcgcg cttatcaata
     9841 tatctataga atgggcaaag cataaaaact tgcatggact aatgcttgaa acccaggaca
     9901 ataaccttat agcttgtaaa ttctatcata attgtggttt caaaatcggc tccgtcgata
     9961 ctatgttata cgccaacttt gaaaacaact ttgaaaaagc tgttttctgg tatttaaggt
    10021 tttagaatgc aaggaacagt gaattggagt tcgtcttgtt ataattagct tcttggggta
    10081 tctttaaata ctgtagaaaa gaggaaggaa ataataaatg gctaaaatga gaatatcacc
    10141 ggaattgaaa aaactgatcg aaaaataccg ctgcgtaaaa gatacggaag gaatgtctcc
    10201 tgctaaggta tataagctgg tgggagaaaa tgaaaaccta tatttaaaaa tgacggacag
    10261 ccggtataaa gggaccacct atgatgtgga acgggaaaag gacatgatgc tatggctgga
    10321 aggaaagctg cctgttccaa aggtcctgca ctttgaacgg catgatggct ggagcaatct
    10381 gctcatgagt gaggccgatg gcgtcctttg ctcggaagag tatgaagatg aacaaagccc
    10441 tgaaaagatt atcgagctgt atgcggagtg catcaggctc tttcactcca tcgacatatc
    10501 ggattgtccc tatacgaata gcttagacag ccgattagcc gaattggatt acttactgaa
    10561 taacgatctg gccgatgtgg attgcgaaaa ctgggaagaa gacactccat ttaaagatcc
    10621 gcgcgagctg tatgattttt taaagacgga aaagcccgaa gaggaacttg tcttttccca
    10681 cggcgacctg ggagacagca acatctttgt gaaagatggc aaagtaagtg gctttattga
    10741 tcttgggaga agcggcaggg cggacaagtg gtatgacatt gccttctgcg tccggtcgat
    10801 cagggaggat atcggggaag aacagtatgt cgagctattt tttgacttac tggggatcaa
    10861 gcctgattgg gagaaaataa aatattatat tttactggat gaattgtttt agtacctaga
    10921 tttagatgtc taaaaagctt taactacaag ctttttagac atctaatctt ttctggctct
    10981 ttgtcaaatg atgttggtaa agagaaatct tagaataatt ggagatcaag tggatcagtt
    11041 cctcttgatc ttttttagtt gaaaatcaat gcgttgccat gacgaatcat gatgcgcaat
    11101 ttgaaattat aaaagctacg aaagccatat gcatttcgtt ttaacacttt gatatggttg
    11161 ttcagacatt caagtgggcc atttgaataa ctttgttgta aagcattttt gatttgtggc
    11221 agaaatttct ggaacgttct caaggtcgtc tgatagcctt cgggaagcat gatattattg
    11281 gtaagtagtt cttcaaacga tacgtagtct cgttccttta cagcgtaaag aaagtcttga
    11341 tataactgat agcctacacg caaagcaggg ctccctttca gtaagcgatc cacaatatcg
    11401 gtctctgtta aatgagcttt gaagccaggt cgccaaaggc gtcgagtata atcaagcttg
    11461 cgttcatctt tttgaagaag tttccagtat ctttttaatt gcttacctaa ttgatagtgt
    11521 ttttgttctt tgctttttaa tagttggttc gtttctttga ttcgatgatt gcgaaaggta
    11581 cgaccaatat gttggacgat gtgaaaccgg tcaataatca gctgtgcttt tggaaacagc
    11641 tttttaacga gcgatacata aggagcgtac atatcaatca cgatccattc gaccgcttca
    11701 cgaatttctc gtgaaaaatg actaaaataa cgttttaaaa aaggcagttg tcggttctcg
    11761 acaatgtcca ataagcgctg tgtttgtcca tccatcatga tgaaactcat agcacctgaa
    11821 acaccccgaa ctgatttgaa ttcatcaaaa caaagtacct taggtaacgg tgtccgaaaa
    11881 ggattcaacg gacgataaaa tcgcttcata atacggtaaa cagaagagac cgatagattt
    11941 ttctgagcgg cgatctctgt cattgaggta ttttttttca gacgagtcac gacagaccag
    12001 cggactttct cactgatgaa acaatgtttt ttcgcaacag aagtatctgc gacaaaggtc
    12061 cgctgacaag ctttgcattt gaagcgttgc tttttcaatt cgaggtaggt acggtattca
    12121 gaaacatcgt tcattaacaa ccggacggtt gttgtacccc aacgcacaat atctgaagca
    12181 atctggtgtt tacagtggat gcattcttgg gctgtataaa tcaagtttcc acgataaata
    12241 tgacagattt gccctttgta tttttctttt gtgagacaat tttcgttaaa agtaactgat
    12301 aagtctagaa tatctaatgt ttctttgata aggtgagtgt aagacatctt gattcctcct
    12361 tttgggttgg ttcgccaaat taattctaaa ggatttcaag gtgtcttttc tatatgtttt
    12421 ggaaaataaa aaagatgctg gtgtcatcca ccaacatcaa aaagtataga gcctcttttc
    12481 tgaagtacat ccgcaactgt ccatactctg atgttttata tcttttctaa aagttcgcta
    12541 gatagagttc tatattagag atgtaaagag ttttggtgaa gaggtttgtg agtatggctt
    12601 ttataaccag ggtgcaatga gaagcactaa cagcagctag cttaagaacg cataggatat
    12661 actttttatg gaagtcacag aggaggaata aaatttgaac aggattaaca gagtaacctc
    12721 tattcttatt cagctgcaat caaaaaaaat aattcctgcc aaagaaattg cacagcgatt
    12781 taatataagc ttaaggacag tttacagaga tatccggaca cttgaagaag ccggaatacc
    12841 aattggatct gaggccggaa aaggatattt tcttgtagag ggcttcctac ttccgccggt
    12901 aatgtttaca gcggcggaag tgggtgcatt gattacagca gggaaatttt taaattgcca
    12961 tggagatgaa tcatttataa aggattttga ttcagctatg tataaaatca aatctatttt
    13021 gaagcatggt gaaaaaaact atgcacagga gttggagaac agtattaacg tgtacagcac
    13081 atctggacag aaaaatacat tggcggataa cgttattgca gcaattcaga ctgcaatctg
    13141 caataaaagg gtaatatcaa ttcaatatcc tgcatcagga gggcaagaac cggaaagcag
    13201 aatgatagag ccggttctgt tgcaaagttt taaataaaga ataaaatccc ttacggtatc
    13261 tatgatttaa gctgggattc ccaataatac cttgatttca gtacagaccg aaaacccgaa
    13321 gagagtgcct tcttttcggg ttttcttata taatcctcga atggcttcca tgcctttaat
    13381 cgtggtagag gcagtgcgta aacttcgata gaatttattg cgtctcttta ctggacgatg
    13441 gtcttgttca atcaaattat tcaggtattt aatggtacga tgttctgtcc cttgataaaa
    13501 gccgtattct tttagtttct taaaggcact tgtaatagag ggggctttat ctgtgactac
    13561 aaccttcggt tcatcaaact gcttcactaa ccgcttaaga aaagcatagg ctgcttgtgt
    13621 gtcccgtttt ttacgtaacc aaatatccaa ggttaaacca tctgcatcga tggctcgata
    13681 caaataatgc cattttcctt taattttgat gtacgtttca tccattttcc atgaataaaa
    13741 ggatttttta tttttctttt tccaaatttg atagagtagt ttgccatatt cttgcaccca
    13801 acgataaatc gtcgtatgag aaacgttaat gccacgatca tataagattt cttgaacttc
    13861 acgatagcta aggttataac gaagatagta gcccacggct acaataatca catcctgctg
    13921 aaattgcttt cctttaaaat gattcatcgt cattcctcct gctatctttt tctattattc
    13981 taccttattt gatagtagat ttaaaacttt gcaacagaac cctatagaga agaataaatt
    14041 catttctact gacgtaaatt tgcgtaaagg aatcgtattt aattcatggt ggtatttcac
    14101 aatttcattt gccataaaat cctccttcaa gattaactac ttaacaaaat tataaagagc
    14161 tttctaatag gggtcaagcc cctaattaaa gacccctaaa aacagacaaa aagaccccca
    14221 aaaacagaca aaaagacccc taaaaacaga caaaaagacc cccaaaagat tctgcacacc
    14281 ttgggagagt aagcatacag ccgacggtaa agaggtttaa aaagaggttt aaaaagagat
    14341 tataaaagag gagaggggca aaatttcccg cctaaaaatt ttctgctttt ttagccaaac
    14401 aggttcgcga attttactaa actgggaaac ttgctccctc tggtcgctaa aaaggtgtga
    14461 gggaaaaaca ccctcacatt gtacctgcgc agtcgcctaa aggctccttt gctaaaaacg
    14521 ttgtttaaag agattttttt agaggctctg cgcgctcgtt taagccgttt taagacagtt
    14581 tagtatggat aacccttatc ttgttcttaa agcaccttac aggcggtcag ggcaagccct
    14641 aacaaccctt aaagagcata aaaccatcct aaaattcgat ttaatctgtc ttatctatgt
    14701 tcttgtatat tttatatacc ttgggtagta aaacgtctga aaacgcaaat aagagcgtat
    14761 gaaacaaaac aataagcaac cgattcagca gaattccgga ggagccattt tcgtacgtta
    14821 gcaaaaaagt gctgttgcta aaagctgctt gcggtgcgga gcgaacaagg tctcctagag
    14881 cgagacgtgt acaaacaagc ttacaaattc gtgaaaggca ccggttttgc gccatttcca
    14941 agcaaaaaaa ggtctatcga gcaagctcga tagaccgatc gcatttagcc ccccgcattc
    15001 taacaggggg ggaataatgt gaaaaattat ggtagtaatg cttgatatat aggcatttct
    15061 tttggttgca cacttaaaaa aaatcacgat tttgacaact aaatttttaa ataaaaaagc
    15121 tttacagttt aattcaaatg tgttttaata tatctatcag tacttgccac gcctctgatt
    15181 taatatcatg cgcattatgg tagggctttt tttttatatt tttttaagaa agaagattct
    15241 tatgaagaca tcaaatagaa aatataaagt taaaacagtt aatcatagaa ttccacctaa
    15301 aaaggcatta tgtgtaatta ataattccaa agtaattaat caagagttaa aaccatattt
    15361 atccgagcaa gaaatgataa aaaaaataag taaagatatt tttttaacaa attccggttc
    15421 tgttgcaaag ttttaaataa agaataaaat cccttacggt atctatgatt taagctggga
    15481 ttcccaataa taccttgatt tcagtacaga ccgaaaaccc gaagagagtg ccttcttttc
    15541 gggttttctt atataatcct cgaatggctt ccatgccttt aatcgtggta gaggcagtgc
    15601 gtaaacttcg atagaattta ttgcgtctct ttactggacg atggtcttgt tcaatcaaat
    15661 tattcaggta tttaatggta cgatgttctg tcccttgata aaagccgtat tcttttagtt
    15721 tcttaaaggc acttgtaata gagggggctt tatctgtgac tacaaccttc ggttcatcaa
    15781 actgcttcac taaccgctta agaaaagcat aggctgcttg tgtgtcccgt tttttacgta
    15841 accaaatatc caaggttaaa ccatctgcat cgatggctcg atacaaataa tgccattttc
    15901 ctttaatttt gatgtacgtt tcatccattt tccatgaata aaaggatttt ttatttttct
    15961 ttttccaaat ttgatagagt agtttgccat attcttgcac ccaacgataa atcgtcgtat
    16021 gagaaacgtt aatgccacga tcatataaga tttcttgaac ttcacgatag ctaaggttat
    16081 aacgaagata gtagcccacg gctacaataa tcacatcctg ctgaaattgc tttcctttaa
    16141 aatgattcat cgtcattcct cctgctatct ttttctatta ttctacctta tttgatagta
    16201 gatttaaaac tttgcaacag aaccgtagcg atcactcctt cttacagcga ccatagggag
    16261 ctagattggc agtttaatat catgcgcgaa cctgtttatt ttaaaaagtg ggtgattttt
    16321 tggcgggaaa ttttgctcgc gcgcgcgcgt ttattttatt tattttttaa agatttttta
    16381 gaaccctttt tagggggcag ttgagcctta ctctcccaac ggatacagaa gggtactaac
    16441 aactttttat ctgagtacta acaacttttt atctgagtac taacaacttt ttatctgagt
    16501 actaatatcc ttttgtataa taacaaccaa cctatttacg agttggttgt taaaggttat
    16561 tatttatttg taaggggggg aagaaaggaa tggatgaaaa aacggaatgg ttctgttgca
    16621 aagttttaaa taaagaataa aatcccttac ggtatctatg atttaagctg ggattcccaa
    16681 taataccttg atttcagtac agaccgaaaa cccgaagaga gtgccttctt ttcgggtttt
    16741 cttatataat cctcgaatgg cttccatgcc tttaatcgtg gtagaggcag tgcgtaaact
    16801 tcgatagaat ttattgcgtc tctttactgg acgatggtct tgttcaatca aattattcag
    16861 gtatttaatg gtacgatgtt ctgtcccttg ataaaagccg tattctttta gtttcttaaa
    16921 ggcacttgta atagaggggg ctttatctgt gactacaacc ttcggttcat caaactgctt
    16981 cactaaccgc ttaagaaaag cataggctgc ttgtgtgtcc cgttttttac gtaaccaaat
    17041 atccaaggtt aaaccatctg caccgatggc tcgatacaaa taatgccatt ttcctttaat
    17101 tttgatgtac gtttcatcca ttttccatga ataaaaggat tttttatttt tctttttcca
    17161 aatttgatag agtagtttgc catattcttg cacccaacga taaatcgtcg tatgagaaac
    17221 gttaatgcca cgatcatata agatttcttg aacttcacga tagctaaggt tataacgaag
    17281 atagtagccc acggctacaa taatcacatc ctgctgaaat tgctttcctt taaaatgatt
    17341 catcgtcatt cctcctgcta tctttttcta ttattctacc ttatttgata gtagatttaa
    17401 aactttgcaa cagaacccga agaacaattg tatttggaaa gtgaaacgag tcaaacgaag
    17461 gtcacagtca gccataatcg tttagacgtg tataaacgtc gtcctgaaac ggtaaaaaaa
    17521 ggaacggagc ttctacgact agaaacagaa aaatacatca tgaatgttta cctagaaagg
    17581 agtgagctgg tcgaaaactt tgtcagctac acgatttgca ggaaacacta ttactcagaa
    17641 tcagaatatt attcaatttt tgagagcatg gaattaatgg aagaagaaat ggaagagcta
    17701 aacagcaaag atgcgacgat agacgattat taccttgtat ttactagatt tttgacgtgt
    17761 ggaacggaat ctatcgtgtt aatgggaatg gattatgaac tcgctgtacc cgaagcattt
    17821 ttgagggaat atgtagaaga agtagataac ccaggcgacg actggtacac gactttaact
    17881 gattttttag acacctatac ttacgacgat acagaagaaa tccaaaatga acttgaccgt
    17941 aaacgaatgc catatcaacg atttgaaagg aaaaaaaggc aataatcatt tataccgaaa
    18001 agtgagaatg tgtgaaataa ggacaaaaaa cctagtaact aagggaatgg ttcttatttc
    18061 gcaccaatcg ctccaaccgc ccccgccgct taggtggtgc gaaataagcg ggcaacaccc
    18121 gataacctaa gagaaagaag gagatccata tgaataaaat cattcctcta ttgttagtcc
    18181 tatttgttgg cgaaatactt atgcgccatg ctgcagctgt gcatttaaac ttcgtagtat
    18241 ttttggcaat actggtattt tgtttgatct tttggcgctt tgtattagcc cttgtgagtc
    18301 tactattcaa gatgattgca gccatatttt tcatagggtt atttcgatga aaggagagag
    18361 tactaatgcc aattgcaata ggaaataaac ggttacccgt tacgttggat gaaaagagac
    18421 aaaaagaatt gcagcaacta aagcagaagt acggcaaaag tgaatccagg attatgtgta
    18481 ttgcgttaga tttattgatt gcccaagaaa aagcaggatt tgaggtacca gcactcaaaa
    18541 agtgacgtca ctttttatcc taaaaactaa aagtgatagc acttttaatt ataagaagtt
    18601 agaatattaa tcatttgctt aattgtacaa tataatgtac aattgtttta tagaaataaa
    18661 taaggggtga aaggaatgga agcagtagct tattcaaatt tccgccaaaa tttacgtagt
    18721 tatatgaaac aagttaatga ggatgctgaa acacttattg taacaagtaa agatgtagaa
    18781 gatacagttg ttgtattatc aaaaagagat tatgattcta tgcaagaaac gttgagaaca
    18841 ctttctaata attacgtcat ggaaaaaatt cgtcgaggag atgaacaatt ctccaaaggt
    18901 gcatttaaaa cacatgactt aatcgaggtt gaatctgatg attaaggctt ggtctgatga
    18961 tgcttgggat gattatcttt attggcatga gcaaggaaac aaaagcaata taaaaaagat
    19021 taacaagtta ataaaagata tcgatcgttc cccctttgct ggattaggaa aacctgagcc
    19081 attaaagcat gatttatctg gaaaatggtc cagaagaatt acagatgaac atagactgat
    19141 atatagagtt gaaaatgaaa cgatatttat ttattctgca aaagatcact attaaccaat
    19201 cggaagtaag gaaagggtca gaaacttaaa agtttttgat ccttatttta tttaccctag
    19261 tcatttaaaa agctaatata gcttagtgtt gattgttatt aatgaatgtg tttgttacgc
    19321 gtattacgga tataaggtta gtaaaatcat ttctaaagtt gaggaaaagt aaatataaat
    19381 ggcttaaatt tcaacaattt gaagttgaat agatatgtta taatactatt gtagtgtggg
    19441 atgttagtta ctaaaggatg acgcttatat atatgactga atagaataag caataggttt
    19501 aataatctat tttaaatttt ttgtactagt tttagttaat tagcaaaaac aacaaaaata
    19561 aacttctcat agaatttagc taaaaattaa tgatttattt acatattaaa tttggataca
    19621 gttaagtaat ttttatatat tggaggagaa gtaatggaat ataaatttaa cttgaatttg
    19681 aaagaagtac tccccactca gggaacaata aacataaatg gtcaagataa tgatgacgat
    19741 atagtaataa aaaaaataga atttattgat tctgatataa atgttttttt ttattctaaa
    19801 gaaaaattag ctgattttag caatattgct gaaatgattg aacgtttaaa agattttatg
    19861 atcagtgttt gggatgtagc gatgcttgct gacgaatcaa attatacttc gagcatatac
    19921 agattagaag atagtaattg gatagaaatt tcattagagt taaagacact tcctaattcc
    19981 gttaactata taattagaga tataacttct gaagctcaac aattagttaa ttacatgcat
    20041 ggacacgaaa gtatcccctt ttctcttata ctccttaaaa gaagtaaaaa tatatcaaat
    20101 actagagata ggtttatttc gataattaca gcctgtgaaa taggggtaaa ggaattttat
    20161 caacaagaga aacctgattt aactctaata tttgagaatt tacaatctcc ccctgtagac
    20221 aaattattag ggagcatgtt taaagggtac tttaatattg agtttccgaa agaaataaga
    20281 aaggaaatta aaaatttcat agaaaaacgt aataaattgg ttcattctcc tcaaggaagt
    20341 aaaccaacta tagaagaatg ttttgaatgt tatatggcag tgctaaaaac atttaatttt
    20401 ttttataaaa ttaatgatag ctttatgtat agagattttt atgaagaatc tatagaattg
    20461 actccaacgg aaccaaataa atctcaaatc actttgtcaa aggagctaga gagaaaagta
    20521 gagtctcaag aactagctat aggaattagt ataaccaatg tgtcgacata caaagaatta
    20581 tacgaagcta aatcacaaga taataaggat tttgtagaaa atatagataa ggaaccaaca
    20641 aatacagtag gggattaacg taaataagtg aagattatat taacagactc tttatttagt
    20701 taagtaaaaa atggtttgtt ggaattttat gctttatctg ttctgagtaa gacttaattt
    20761 tatagatagt aattatatgt aggaaattaa agatgagaag ataataaaag cagcatgatc
    20821 aactatttgt cattgaccat gctgtctttt tttattctat acacggtttg tctcgtaaca
    20881 ttgtagtctt tagcaatctt agcaatcgca acaccatttt taagatcttc aacgatgctt
    20941 ttgtaaacaa ggcgacgttg gggatctttt gcgtctgcac tgtataattt gggccgccct
    21001 ttgtagacgc cgtttgcttt tgcgatctta attccttgtg cctggcgacg tttcgattca
    21061 gtccgttctt gttcagcgat catggccaaa atttggatga tcagatcctt aatgaattta
    21121 tccaggagag gattgccaat tgcttcagcc atgatcggta aactagtaat gatcagcttc
    21181 acatttttct tcttcaagta attgactgaa gcgatgatct cgtcataatt tcttccaagt
    21241 cgatcaatag cttccacaat aaaaatatct tgatctcgga cgtaatctaa tgcttcttgg
    21301 aaaacaggtc gatgagtaat cgttgcgcca gattgtttct cgatgaaaat tctctctgca
    21361 ccgaattttt tcatttcttc aatctggcgt tgttcatttt gatcgatcga tgagacacgt
    21421 atgtatgcaa ctctcaaaac ttttacctac tttctgcaac tatttaaaat acaccctaat
    21481 catacacgag gaagccatat ttttcaatgt tataccagtg tctatttagg gtatacctta
    21541 tatagacaaa aactaatgat ggaggaaata gtatgagaat tttttgtaag tgtctactga
    21601 taacttattc tcaaatgttg taaggatttt attcatttgt taatattaaa gaacggaact
    21661 ccaaaaaagt ccgtactcta atttgcagtc tctcactctt ttagagtgag agtttttatt
    21721 agattttcaa attaattagt aaagtgatag aataaattga tcatacaaat caaaagaaga
    21781 agcagggtga tagcatacct atgcttcttt ttttatgtat ttagctattt cttctttaca
    21841 atatcgaaca tatgtttgta taatgtgaaa gaatggagtg ttatttatga tggattattc
    21901 aaaagagcca gtaaatgatt actttttaat cgatatgaaa agcttttacg caagtgtcga
    21961 atgtatagaa agaaatttag atccattaac aacagaactt gttgttatga gtcgagctga
    22021 taatactggt tcaggattga tattagcttc ttctcctgaa gcaaaaaagc ggtatggtat
    22081 tacaaatgtg agtagaccac gtgacttacc acaaccattt cctaaaacac tacacgttgt
    22141 tccaccacgt atgaacctat atatcaagcg aaatatgcag gtaaataata ttttcagaag
    22201 atatgtggct gatgaagatc tactgattta ctcgatcgat gaatcaatct taaaagtgac
    22261 ccgatcactg aatcttttta cgactgaagg aacacgaagt caacggagaa agaagctggc
    22321 tcaaatgatc caggagaata ttaaagaaga gctaggattg attgctacag taggtgtcgg
    22381 agataatccc cttttggcta aactagcctt agacaacgaa gcaaagcata atgaaggatt
    22441 tgttgcggaa tggacgtacg aaaacgttcc tgaaaaagta tggaatattc ctgaaatgac
    22501 ggacttttgg ggaattggct ctcgaatgaa aaaaagactc aatcagatgg ggattatgag
    22561 cattagagat cttgctaact ggaatcctta tacgattaag aatagactag gtgtgattgg
    22621 cttacagctg tacttccatg ctaatgggat cgatcgaaca gatatagcaa tcccaccaga
    22681 accgacaaag gaaaaatcat atggaaattc acaagtgtta ccacgagatt atactagaag
    22741 aaatgaaatc gagctggtgg taaaagaaat ggcggaacaa gtagcgatac gcattaggca
    22801 gcataactgt aaaacaggtt gtgtccattt acacattggc acgtcgatct tagaaacgag
    22861 accagggttt tcacaccaga tgaagatccc tatcacagat aatacaaagg aattgcagaa
    22921 ttattgtctt ttcttgtttg ataagtatta tgaaggacaa gaagtaaggc atgttggaat
    22981 aacctatagc aagcttgtgt acaccgattc gcttcagctg gatttattta gtgatccaca
    23041 aaagcaaatt gacgaagaaa atttagataa aattattgac aagattcggc aaaaatatgg
    23101 ttttacgtcg attgtacatg cttcttcaat gttagaaggc gctagaagca ttactagaag
    23161 cacacttgtt ggtggtcatg cgggcggaaa tgggggaatt aaaaatgatt gattacaatg
    23221 atcgtggacg tttaaagtgg gcagggtttt atttatctga tcatactgaa gaaattgatg
    23281 ccgacaatga acaacgaacc agtcaaaatt tagcaaaaga acaaatgacg actgaagaga
    23341 ttgcggaagt attgaacgct gcagtcataa aaaatagatc agtatctatt caaaaagaag
    23401 aacgaaacgc tgaaggatac tatccagaag atatcattgg caagatctta ggtagtgatg
    23461 agctggggat ctacgttgga aaagacaaaa ttcactacga cgaaatacgt catatcgaat
    23521 tttaccagga taataaatgg agtcgattag aatgaacatt atccagcaat atgagctaaa
    23581 gtatataacc tttgatcagc tatcagaaga gatttggggt tatggccaac gtttgataaa
    23641 tgaggttggt gttgagcgct tctctttcta tgtagaagct gcagcaggtt atcataattt
    23701 taggttttat atcttcccgt tatatatata aggtatttta cggattctat agagttatct
    23761 ctatgaatcc ttttttgttt ttacaaatag gagtagatac tagaataatg cgtgtgttaa
    23821 actattattg caaacgcaat aataaaagaa agtaggctta cgcaccatgt ctatcaatac
    23881 atttgtttac tcgcacccga tcaatgttta cattatcaag aatttaggaa tcactgtaga
    23941 acaattttgt gagttatatg cctacccaca aggaacggtt gcaagctgga taacccgaca
    24001 acgtagaata aaatcattac ctgcttcatt cgtttatgat ttaagcctgg cctctagttt
    24061 aaacatgtct gatgtttatg aaaagctcct gtctttagaa aaagaatatg attccttcaa
    24121 gattaaacat gataaaaaaa taaaaaaaca tatataatat caatcacaat tgtataatat
    24181 tacgatatct taatatcatg atatcgtaat attgtttttt tctaagaaaa tgcactataa
    24241 gaagggaatt attagtaaca atatagacag tttagtaatg tttaaattat tctagttgct
    24301 gctcgcaaaa catatttctt atcattaata aaaaatttta aagtaataaa aagtgattat
    24361 tttaatttcg aataacatat gaataatctt tatatccgaa ccgatatata tctttaaaac
    24421 aaaataatca cacaatatta caatataatg catatacgat attgcaatat cacaatatta
    24481 tgatataatt atattataat ataagatgaa tgggggatat tttaatggca agaatattgt
    24541 cagtagccaa tcaaaaaggt ggagtttcta aaactacgac tagcgttaat ttagcagcat
    24601 gtttgaaatt tgtttacggt aaaaatgtac ttttagtgga cattgatcct cagggaaatg
    24661 ctacagataa tgtaggtttc gatatagatg gaacaaacca acctacaatt tatgaagtat
    24721 taaaagggga ggctgacatt acagatgcta ttctggacta taaaggaatt gatgttttgc
    24781 cagccgacat agccctttct tctgcagaga gggaatttac tcaagtagga agtgaacaca
    24841 ggcttaaaag agtacttcaa ccaatcaagg acaactatga ttatattata attgattgtc
    24901 caccaagttt aggaatgctt acagtcaacg catttactgt ttctgatgaa attatcattc
    24961 cagttgaagc tgcgtatttc tcattaaaag gactaataaa gttaagtgaa actattgaaa
    25021 cggtaaaaga atatacgaac gacaagcttg aagtacgagg agttctattt actaagtata
    25081 ataagcgtta taacatttct aaagaaatga cgtctgcagc aaccgaaatt tctagagtca
    25141 ttggtgcaaa aattttcaaa acttatattc gtaggacaat aaccgttgac gaagcgcaag
    25201 ctgctggatc agatctaatc aattttaata aaccctcaac agctgaagat gactataaag
    25261 catttacaga agaatattta aaagaagttg gtgattttga tggcagaaga taatcgcagt
    25321 caagctgcag taagtagatt actaggaaat aaaaataaaa agaattttaa atcaaaagaa
    25381 gtagaagaaa tcgaattaac caagaaaaat ataagtaaag tcataaaaga tcaaggaagt
    25441 agtgtaagaa cagcagatag cattcgtata aatccaattc taatgtcagc actcaaatat
    25501 tggacgacta ttgctgaatc agacaaaagt aaaccagacg ttatagaaga tgcgctatta
    25561 aagtccatac ctgaagaata cttgattgaa ggatataaac tagcaaagaa acaaaataaa
    25621 atttaattta cattcaatat cacgatatca taatatcgtg atattttttt tataaaaatc
    25681 agtagtatca aagctgataa gtcgcttatc ttcatattgt aatattacga tatcgtgata
    25741 taatattatt gtaatatcgt gatatagtta ctatgagctt aaaccttgaa atagagcggt
    25801 ttgctttaat ttatttttta aggtaaacta aaaaaagata aaaaaagact actgctttaa
    25861 caaagtttgg cgacttatca gcagtagaaa aatatatagt ggatagatat atttgtttaa
    25921 ttcattgtaa catagttttg aacaaaacgc tatcctacag aaagaggatt ggct
//
