LOCUS       NZ_CP066533             6373 bp    DNA     circular CON 30-NOV-2023
DEFINITION  Klebsiella pneumoniae strain WCHKP090361 plasmid p3_090361, complete
            sequence.
ACCESSION   NZ_CP066533
VERSION     NZ_CP066533.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN15649156
            Assembly: GCF_014041645.2
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 6373)
  AUTHORS   Wei,L., Wen,H., Liu,L., Feng,Y. and Zong,Z.
  TITLE     The complete genome of Klebsiella pneumoniae strain 090361
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6373)
  AUTHORS   Wei,L., Wen,H., Liu,L., Feng,Y. and Zong,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-DEC-2020) Center of Infectious Diseases, West China
            Hospital, Sichuan University, Guoxuexiang 37, Chengdu, Sichuan
            610041, China
REFERENCE   3  (bases 1 to 6373)
  AUTHORS   Wei,L., Wen,H., Feng,Y. and Zong,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-JUL-2020) Center of Infectious Diseases, West China
            Hospital, Sichuan University, Guoxuexiang 37, Chengdu, Sichuan
            610041, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 150.0x
            Sequencing Technology :: Illumina HiSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/30/2023 02:50:20
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,858
            CDSs (total)                      :: 5,737
            Genes (coding)                    :: 5,571
            CDSs (with protein)               :: 5,571
            Genes (RNA)                       :: 121
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 166
            CDSs (without protein)            :: 166
            Pseudo Genes (ambiguous residues) :: 0 of 166
            Pseudo Genes (frameshifted)       :: 59 of 166
            Pseudo Genes (incomplete)         :: 113 of 166
            Pseudo Genes (internal stop)      :: 19 of 166
            Pseudo Genes (multiple problems)  :: 23 of 166
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP066533.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..6373
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="WCHKP090361"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="p3_090361"
                     /geo_loc_name="China: Chengdu, Sichuan"
                     /collection_date="2019-06-19"
     gene            395..553
                     /locus_tag="H3G66_RS29610"
     CDS             395..553
                     /locus_tag="H3G66_RS29610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_071596352.1"
                     /translation="MHEPPVQPDCCALSGNYHLESNPDGHAKTPLAAAIGNWIYTREIL
                     RGLEVGA"
                     /name="replication initiation protein"
     gene            911..1237
                     /locus_tag="H3G66_RS29000"
                     /old_locus_tag="H3G66_029000"
     CDS             911..1237
                     /locus_tag="H3G66_RS29000"
                     /old_locus_tag="H3G66_029000"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_050516389.1"
                     /translation="MRERTNIMLDIGLKQSLQRLSNKTKMSLSDLINQRLSGSLSVEER
                     IGEKPEWMRNLDPYLANHFSNIELPLPSPLKEYQEKMDEIDSIINDMMVLKEYFRAKFY
                     DEIK"
                     /name="hypothetical protein"
     gene            1263..1808
                     /locus_tag="H3G66_RS29005"
                     /old_locus_tag="H3G66_029005"
     CDS             1263..1808
                     /locus_tag="H3G66_RS29005"
                     /old_locus_tag="H3G66_029005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_023317533.1"
                     /translation="MFFKRYLTEKEIYKAALPIVRLQGRVNTSLRFLSKYSDVNKNGLI
                     ALHLNLLHFISYNIHGVESLKITQAGINKAVQQSPHADEIKNIAQAIGRKGPEYIEGLI
                     RNPWGKKNDNPLIFIMSIEESIKETLNSGYMLYRVAPITEGEAAAFMDVLKQLLLFEDN
                     FRLFGRDLVYKIEKLKIR"
                     /name="hypothetical protein"
     gene            complement(2210..2907)
                     /locus_tag="H3G66_RS29010"
                     /old_locus_tag="H3G66_029010"
     CDS             complement(join(2210..2658,2658..2907))
                     /locus_tag="H3G66_RS29010"
                     /old_locus_tag="H3G66_029010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558267.1"
                     /ribosomal_slippage=""
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /protein_id="WP_223174630.1"
                     /translation="MASVSVCCPSCSATEGVMRNGKSTAGHQRYLCSHCRKTWQLTFTY
                     AASQPGTHQKIIDMAMNGVGCRATARLMGVGLNTILRHFKKLRPQSVTSRIQPGSDVIV
                     CAEMDEQWGYVGAKSRQRWLFYAYDRIRRAVVAHVFGERTMATLERLLSLLSVFDVVVW
                     MTDGWPMYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSFSKSVELHDKVI
                     GHYLNIKHYQ"
                     /name="IS1 family transposase"
     gene            complement(3071..3337)
                     /locus_tag="H3G66_RS29015"
                     /old_locus_tag="H3G66_029015"
     CDS             complement(3071..3337)
                     /locus_tag="H3G66_RS29015"
                     /old_locus_tag="H3G66_029015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262326.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_004197762.1"
                     /translation="MVWTINYSDRALKSLRKMDKQNARRIVDFMSLRIAVAADPRQSGK
                     PLKGELGEFWRYRVGDYRVLCEIRDDELVILAATIGHRREVYD"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(3321..3545)
                     /locus_tag="H3G66_RS29020"
                     /old_locus_tag="H3G66_029020"
     CDS             complement(3321..3545)
                     /locus_tag="H3G66_RS29020"
                     /old_locus_tag="H3G66_029020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6290 family protein"
                     /protein_id="WP_000879771.1"
                     /translation="MLAIRLSDEIESRLDSLAKQTGRTKTFYAREAILAHLEDLEDYYL
                     SAETAARVRRGDEAVHSSEDVRKSLGLDD"
                     /name="DUF6290 family protein"
     gene            3708..3836
                     /locus_tag="H3G66_RS29515"
     CDS             3708..3836
                     /locus_tag="H3G66_RS29515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000523570.1"
                     /translation="MGLKPGPKRIADSTGEPDKRQRDNKKTPGNTDKLKPSKSSKK"
                     /name="hypothetical protein"
     gene            complement(4212..4424)
                     /locus_tag="H3G66_RS29025"
                     /old_locus_tag="H3G66_029025"
     CDS             complement(4212..4424)
                     /locus_tag="H3G66_RS29025"
                     /old_locus_tag="H3G66_029025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeD family mobilization/exclusion protein"
                     /protein_id="WP_021527181.1"
                     /translation="MTELEKQLLSALEQLQQDYSKRLDEWESAFGEWRKMSGLMQRENA
                     ALSERVTRLSQQVERLSGQLQRLSR"
                     /name="MbeD family mobilization/exclusion protein"
     gene            complement(4431..4940)
                     /locus_tag="H3G66_RS29030"
                     /old_locus_tag="H3G66_029030"
     CDS             complement(4431..4940)
                     /locus_tag="H3G66_RS29030"
                     /old_locus_tag="H3G66_029030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020325392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeB family mobilization protein"
                     /protein_id="WP_032433972.1"
                     /translation="MNSLLTLAKDLEQKSKAQQQSTGEMLKAAFSEHEKSVRAELSESG
                     KRISAAIRAHEQGMSAAMQSNRLSVMRMVGRTWLTITMVSGLLFASLSGVLWYQGSLIA
                     SNLAEIDRQNAALSKLNAKTWGVTYLEDSNGRFLVLPKGTAVDRTQSWTVGNGRSKQNA
                     LRLVKE"
                     /name="MbeB family mobilization protein"
     gene            complement(<4975..5679)
                     /locus_tag="H3G66_RS29615"
                     /old_locus_tag="H3G66_029035"
                     /pseudo=""
     CDS             complement(<4975..5679)
                     /locus_tag="H3G66_RS29615"
                     /old_locus_tag="H3G66_029035"
                     /inference="COORDINATES: protein motif:HMM:NF015397.3"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(5618..5962)
                     /locus_tag="H3G66_RS29040"
                     /old_locus_tag="H3G66_029040"
     CDS             complement(5618..5962)
                     /locus_tag="H3G66_RS29040"
                     /old_locus_tag="H3G66_029040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006122514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="WP_062955149.1"
                     /translation="MAVKRTRFLGIRVTDGEYQQLLERCNGRQLAVWMRETCLDTRPAR
                     SLRLPSIDPVLLRQLAGMGNNLNQIARKINGGQWSGADRVQVVAALMAIDAELERLRHA
                     VLEKGADDDR"
                     /name="MobC family plasmid mobilization relaxosome protein"
     gene            complement(5952..6128)
                     /locus_tag="H3G66_RS29045"
                     /old_locus_tag="H3G66_029045"
     CDS             complement(5952..6128)
                     /locus_tag="H3G66_RS29045"
                     /old_locus_tag="H3G66_029045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004197757.1"
                     /translation="MQKPKKKPLVVKKRSWHPAVMANLMRQAQEEDYRREQMAELERSA
                     RSHFADIGGEDGG"
                     /name="hypothetical protein"
     Typing          complement(6215..6291)
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="91.25"
                     /coverage="98.0"
                     /evalue="1.04e-21"
     Typing          107..504
                     /name="rep_cluster_2370"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="89.526"
                     /coverage="91.0"
                     /evalue="3.03e-139"
     Typing          complement(4097..5628)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.804"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 aatgacgcct cctcgctcac tcggtagctg cgctcctgcc gttcggctgc ggcgggcgtg
       61 accgactcac ggataacggg ataaagcaaa ggcgctcaaa tcagaaaggg ccggagaaaa
      121 ggatgcggcg ttgccgtttt tccataggct ccgcctcccc tgacgagcat cacagaaatg
      181 gacgctcaag tcagaggagg acgaaacccg acaggactta aagatgccgg tgatttctct
      241 ccggcggctc cctcgtgcgc tctcctgttc cgaccctgcc gtttaccgga tacctgttcc
      301 gcctttttcc ctttcgggaa gcgtggcgct ttctcatagc tcacgctgct ggtatctcgg
      361 ctcggtttag gtcgttcgct ccaagctggg ctgtatgcac gaaccccccg ttcagcccga
      421 ctgctgcgcc ctttccggta actatcatct tgagtccaac ccggacggac acgcaaaaac
      481 gccactggca gcagccattg gtaactggat atatacgaga gagatattga gaggtcttga
      541 agtgggtgcc taactgcggc tacactgaaa gaacagtttt ggtatctgcg gtctcgtata
      601 cccagttacc cggttaagca gttccccaac tgacttaacc ttcgatcaaa ccgcctcccc
      661 aggcggtttt ttcgtttaca gtgcaagaga ttacgcgcag aaaaaaagga tctcaagaag
      721 atcctttaaa tgatcgtcag ttctgttatc cccggagctc catccatccc acggaaaaac
      781 acccgccact gatgccctca gcgcactgca catcatgtac aaaccactcc ctccctcctt
      841 ttttattgcg tttcttaatg cgcaatggta gctttgtgcg caacaaaaaa cgcaatagca
      901 agggggggta atgagagaaa gaacaaatat catgctagat ataggattaa agcaatcctt
      961 acaacggctt tcgaataaaa ccaaaatgag tctaagtgat cttattaacc agagattatc
     1021 aggttcactt tcagttgaag aacgcattgg cgaaaagcct gaatggatga gaaaccttga
     1081 tccctatctc gccaatcact tttcaaatat tgagttaccg ctcccttcac cattaaaaga
     1141 ataccaagaa aaaatggatg agatagattc aattattaat gacatgatgg ttctaaagga
     1201 atatttcaga gctaagtttt acgacgaaat aaaataggca cgctatacgg aggcggagaa
     1261 ttatgttttt taaacggtat ttaacggaga aggaaatata caaggcagca ctcccaattg
     1321 ttaggcttca agggagagtt aacacttcat tacgtttttt atccaaatac tcagatgtaa
     1381 acaaaaatgg attaattgca ttgcatctta atttattaca ttttatctca tacaacatac
     1441 acggtgtaga gtctctgaaa atcactcaag caggcataaa caaagctgta caacaaagcc
     1501 ctcacgcaga tgaaataaaa aatattgcgc aggcaatagg acgcaaagga cctgagtaca
     1561 tcgaaggatt aattagaaac ccatggggga agaaaaatga taatccacta atatttataa
     1621 tgagcattga agaaagtata aaagaaaccc ttaactcagg ttatatgtta tatagagtag
     1681 ctcccataac tgagggtgaa gcagctgctt tcatggatgt tcttaaacaa ttattattat
     1741 ttgaggataa ttttcgcctt tttggtagag acttggttta taaaatagaa aaattaaaaa
     1801 tcagataaca aagtatggtg aacgaaaaat gaaagagagg atagtgaaat gtgtaatacc
     1861 aagattctca actatgtatt ggttaattgc gttcctagca tttatattcc ccggtcgatc
     1921 ttttgctgac ggttacaccg cttactaccg atgtaatggt actcaggaag catctcttac
     1981 tgttaaagat aacaaactaa gtatggttgt aggtctttct aagtttaata ggcaactgga
     2041 tacttataga ttcaaagaaa agggaatcga agtagtaatg cagagagctg cttctgatga
     2101 taactctgag gccataatgt cttttattat gcctgacgtt aacaatatga ccttattagt
     2161 taaaaataac ggctacatta tcgttaagac aaccggtaat gactccaatt tactgatagt
     2221 gttttatgtt cagatagtgc ccgatgactt tgtcatgcag ctccaccgat tttgagaacg
     2281 acagggactt cctgcccagc cttgccagat gctgtctcag attcaggttg tgtcgctcaa
     2341 ttcgctgcgt gtaacgctta ctgatgacgt gcagttttcc cttcagacgt gactcataca
     2401 tcggccagcc gtccgtcatc cataccacca cgtcaaaaac tgacagcagg ctcagaagac
     2461 gctccagtgt ggccatagtg cgttcaccga aaacgtgggc taccaccgcc ctgcgtatcc
     2521 tgtcatacgc gtaaaacagc cagcgctgac gtgattttgc accgacgtag ccccattgct
     2581 cgtccatctc cgcacagaca atgacatcac tgcccggctg tatccgggag gttactgact
     2641 gcggcctgag ttttttaaat ggcgcaaaat ggtgttgagg cccacgccca ttagtcgtgc
     2701 ggtggcacgg caaccgacgc cgttcatagc catatcaatg attttctggt gtgtaccggg
     2761 ctgagaagcg gcataagtga aggtgagctg ccatgtttta cggcagtgag agcagagata
     2821 acgttgatgc ccggcagtac ttttgccatt acgcatcacg ccttcagtag cggaacagga
     2881 gggacagcag acggagactg aagccacggg agcacctcaa aaacaccatt atacactaaa
     2941 tcagcaagtt ggtagcatca ccaagacaac ctgctggtta actaaaaccg acaaacagta
     3001 gaacacgtag ttagtcgagt atttaccata atacctgttg tcggcatcaa aaaagcccgc
     3061 atagcgggct tcagtcgtaa acttcgcggc gatgtccaat cgtggcggca aggataacaa
     3121 gctcgtcatc tcggatctca cacagaacgc gataatctcc cacccgatag cgccagaact
     3181 cgcccagctc acctttgagc ggcttccctg actggcgagg atcggcagca actgcaatgc
     3241 gtaaactcat aaaatccaca atccgtcgtg cgttctgttt gtccatcttg cgtaacgatt
     3301 tgagcgcccg atcggaatag ttaatcgtcc agaccaagtg acttcctcac gtcttcagac
     3361 gaatgcactg cttcatcacc acggcgaacg cgtgcagcag tttctgctga aagataataa
     3421 tcctccaggt cttccagatg cgccagtatt gcttcccgcg cataaaacgt ctttgttctg
     3481 ccggtttgct tcgccagcga gtccagacgg gactcaatct catcagataa ccggatagca
     3541 agcatataaa cctcccgaac accatttgct atacatgtat atcaacagta ccacaatcaa
     3601 cctaaaagaa caaaaaataa tcttgttagc ccctcttgat aatccgtaac gcggtcaata
     3661 tatctagctt gagggctttc ctcttaacta ttgaaaggat aacgattatg ggtcttaagc
     3721 cgggtccgaa acgaattgcc gattcaacag gggaacctga taaacgccag cgtgacaata
     3781 aaaaaacgcc gggaaatact gacaaattga aacccagcaa atcttcaaaa aaataagtca
     3841 gtagttaaaa gccctccggg gcttttttgt atctgccgtt cacgctgatt aaacataaca
     3901 cccgttgccc gcaccgcccc ggacgggttc gccgcgaacg gggtggcagt caggtaaaac
     3961 cggcaacaaa ccacccgata aaccgccccg ttcgcgacag ataaatttta cctggctgca
     4021 tagccatgca gccaggtgaa tgacatccgg tttcagcgta aatgcccgat gagaaccctg
     4081 ttttcctgca tttcagccca gcgacggacc gtcatagctt cgctgccggg aacgcgcttc
     4141 cgtcagttcc ttttcgtgct gccgttgctc gtgcgcccgt tctgcggcca cggccatctc
     4201 atgacgctgc actaccggct caaacgctgc agttgcccgc tcaagcgttc cacctgctga
     4261 ctcaagcgcg tcacgcgctc gctcagcgcc gcgttctccc gttgcataag ccctgacatt
     4321 ttccgccatt ccccgaaggc gctctcccac tcgtccagcc ttttcgagta gtcctgctgt
     4381 agctgctcta atgcgctcag caactgtttt tccagctcgg tcatcggcac ttactccttc
     4441 accagtctca gcgcgttctg cttcgaccgc ccgttcccga ccgtccagct ctgcgtcctg
     4501 tctacggccg tccccttcgg cagcaccaga aaacgtccgt tgctgtcttc caggtacgtc
     4561 acgccccagg tcttcgcgtt cagcttcgac agcgctgcgt tctgccggtc gatttcggcc
     4621 agatttgacg ctatcaagct cccctgatac cacaacaccc cgctcaggct ggcgaacagc
     4681 agtcctgaca ccatcgtgat ggtcagccat gtccgcccga ccatacgcat cacgctcagg
     4741 cggttcgact gcatggccgc gctcataccc tgctcgtggg cgcggatggc ggcgctgatt
     4801 ctcttcccgc tttcgctcag ttccgctctg acagacttct cgtgctcgct gaatgcggct
     4861 ttcagcattt cgccggtact ctgctgctgc gctttcgatt tctgctctaa gtccttcgcc
     4921 agcgttaaaa gactgttcat agatggctcc cttaagtcgg atgtttcgcc ctccgtccgg
     4981 gtcggcaatg ctgatgctgc tctttgtggt gcgcacgacc tcaaaacctg cgctttccag
     5041 cgcctcagtg acgtcctgac gcgttttaag ctcccctgac gaggcgaggg ccagtaagcc
     5101 ccgcgtaata gcctctgcgg cttcctgctt cgttttgggt aacgaagatg gcgtcaccag
     5161 cgcgcgccgg ttctccggtg cgttcgggtc gtgcagcccc agtcgcccgt tcaccacggt
     5221 ctgccacgca tcgatgcgcg gacggtctgc ccggtcgtag tacggctgga gacgcctgcc
     5281 ggtcagcagt tccgtgttcg gtaccagaaa attcagttcc agccgcccct tgtcccggtg
     5341 ttcaacccac agcacgctgt actggtcttt atcgagtccg ggcatcagaa cccgctcgaa
     5401 gctcgccatc agcttttcac gctggccggg cggtaaatcc tgttcagcaa aagacaggac
     5461 gccggaggtg tactttttgg cgtagggcga ggcgtcgata agctcccgga cctcctccgg
     5521 ctttccctgc aggacgatgg ccccgtcgcg ctggcggtct ttccccagca gataatccac
     5581 cggcccggca ccgccgcctc gccctcgcgg atgaaactta acgatcatcg tctgccccct
     5641 tttccagcac ggcatgccgc agccgctcga gttcggcatc aatggccatc agcgcggcca
     5701 ccacctgaac ccggtcagcg cctgaccact ggccgccgtt aattttccgg gcgatctggt
     5761 tgaggttgtt ccccatcccg gcaagctggc gcagcaaaac cggatcgatg gacggcagcc
     5821 gcaacgaccg cgccgggcgc gtatcgagac aggtttcccg catccacacc gccagttgcc
     5881 ttccattgca gcgctccagc agctgctggt actccccatc ggtcacccgg atacctaaaa
     5941 aacgggtacg cttaaccgcc atcctctcct ccgatatccg caaaatgtga ccgggctgaa
     6001 cgctcaagct ctgccatctg ctcccggcgg taatcttcct cctgtgcctg acgcatcaga
     6061 tttgccatca ctgccggatg ccaggatctt ttttttacga cgagcggctt cttcttcggc
     6121 ttctgcatta tccctccttc gcaaacgccg gacggcacgg aaaagttttc cgggtcgctc
     6181 cggcgttgga caagcgccag cgcgtcagtg gtgttagcgg gtttcggggc gcagccctga
     6241 accagtcaca gcgtttacgc tgtgtatact ggcttactat gttggcatga gagcacgatt
     6301 catgaaagtg cctcatgtgg caggtgtgat atgtggctca ggagcgtccg caataccatg
     6361 cacggacaga tga
//
