LOCUS       NZ_CP066386             6895 bp    DNA     circular CON 20-FEB-2024
DEFINITION  Enterococcus faecium strain Dallas 16_1 plasmid p16_1_6.8kb,
            complete sequence.
ACCESSION   NZ_CP066386
VERSION     NZ_CP066386.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN17038069
            Assembly: GCF_016406485.1
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6895)
  AUTHORS   Islam,M.J. and Palmer,K.
  TITLE     Molecular characterization of VREfm isolates from Dallas, Texas
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6895)
  AUTHORS   Islam,M.J. and Palmer,K.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-DEC-2020) Biological Sciences, University of Texas at
            Dallas, 1520 Richardson Dr Apt 1418, Richardson, TX 75080, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2019
            Assembly Method                   :: Unicycler v. 0.4.7
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 247.0x
            Sequencing Technology :: Illumina NextSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/20/2024 03:07:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,275
            CDSs (total)                      :: 3,183
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 92
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 165
            CDSs (without protein)            :: 165
            Pseudo Genes (ambiguous residues) :: 0 of 165
            Pseudo Genes (frameshifted)       :: 72 of 165
            Pseudo Genes (incomplete)         :: 85 of 165
            Pseudo Genes (internal stop)      :: 37 of 165
            Pseudo Genes (multiple problems)  :: 24 of 165
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP066386.1.
            Bacteria and source DNA available from Dr. Kelli Palmer, UTDallas.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..6895
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /strain="Dallas 16_1"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /plasmid="p16_1_6.8kb"
                     /geo_loc_name="USA: Dallas"
                     /collection_date="2015"
     gene            1..933
                     /locus_tag="JCP87_RS16135"
                     /old_locus_tag="JCP87_16135"
     CDS             1..933
                     /locus_tag="JCP87_RS16135"
                     /old_locus_tag="JCP87_16135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_002313300.1"
                     /translation="MANEIVKYEPELNTIPLRKFTPIEMNLFFSIVSRMRDKGNQKIRF
                     YFSQLKDLSAYKQTAGEVFIKDLARTYDHLMDLRFGRKSNGGLTIERFTMFTDFEIHGE
                     VDNPYVDIKVHEKALPLLNNLESWVRFSLTEFRDLNSSYAKTMFRLLKQYRTQGWAEFS
                     KEDFLELLDIPKSYRQTNINQFVLKPIKEELTPLFKGLTIRKKYGKGRGKPVIGYRFTW
                     KAEINHADDFSKGKQEDLRIKLFNIEHNGELTQKEKWRAKDRILNLPLGTHEADFKKQQ
                     QTEKEEAEKQSISNELKQDLLENLQNLFD"
                     /name="replication initiation protein"
     gene            950..1420
                     /locus_tag="JCP87_RS16140"
                     /old_locus_tag="JCP87_16140"
     CDS             950..1420
                     /locus_tag="JCP87_RS16140"
                     /old_locus_tag="JCP87_16140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_002302544.1"
                     /translation="MIDKTIKELAEEFHVSKQAIRKRLSADFRENYVQTVTRNGVKTLV
                     VSYKGYLLLKQHFLGSNTTGNQVETVASNDENSIIVFLHEQLQEKDTQIKQMQKLLDQQ
                     QQLTLQANQQIEKLQEQLQLAYTEEPEEEELTSVNKENNNAITTEKKWWKFW"
                     /name="DUF536 domain-containing protein"
     gene            1504..1956
                     /locus_tag="JCP87_RS16145"
                     /old_locus_tag="JCP87_16145"
     CDS             1504..1956
                     /locus_tag="JCP87_RS16145"
                     /old_locus_tag="JCP87_16145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339186.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_060806732.1"
                     /translation="MTISKVIKQKRIEKQLTQEDLAEMLLVSKKTISNWENGRTIPDTE
                     NLIQFAKLFDLSLDNILLGEEKIMVKNHTKTLILLFHFVIFLSLVFTLIQSGFFYFSHS
                     IATWLLIFFLSLLLIINTLIIIFNKHRNLFLHSIFPIVLLIFLYFI"
                     /name="helix-turn-helix transcriptional regulator"
     gene            2083..3264
                     /locus_tag="JCP87_RS16150"
                     /old_locus_tag="JCP87_16150"
     CDS             2083..3264
                     /locus_tag="JCP87_RS16150"
                     /old_locus_tag="JCP87_16150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313302.1"
                     /GO_process="GO:0051301 - cell division [Evidence IEA];
                     GO:0009252 - peptidoglycan biosynthetic process [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="WP_002302539.1"
                     /translation="MKNNRIYKNQLNYGLLLPVFLLCIIGLLSLYVALYHDSYTNSKIT
                     KELIKQVLWYSIGFTSAITIYFFNPKILWKLTPIFYGLCIIMLLLLLKFYNPQLAVLTG
                     AKNWFYIAGFSFQPTELVKIGYTLMLAKITVNYQQKSITSNTKDDWIYLLKTFIATLPI
                     GILLFFQNDLGTMLVFIVIYIFILFTSNINIKIIAPIIAIGVVLSLIFLYLVISDTGRD
                     FLLKIGFHDYQFKRIDSWLNPFLDPNGSSYQLANSLIAIGSGGLLGTGFNVSNIHVPVR
                     ESDMIFSVIGENFGFIGSCLVIFLYFYLIYQMYKTCFKSNNLFFTYIGIGIVAMIFFHV
                     FENIGASIGLLPLTGIPLPYISQGGSAILSNFLGLGFMLCCSRYTNEKKGTQK"
                     /name="FtsW/RodA/SpoVE family cell cycle protein"
     gene            complement(3480..4628)
                     /gene="tnpB"
                     /locus_tag="JCP87_RS16155"
                     /old_locus_tag="JCP87_16155"
     CDS             complement(3480..4628)
                     /gene="tnpB"
                     /locus_tag="JCP87_RS16155"
                     /old_locus_tag="JCP87_16155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element RNA-guided
                     endonuclease TnpB"
                     /protein_id="WP_002287525.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYEE
                     VKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRFKS
                     KKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSSGKY
                     YISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQRKLS
                     RRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDIICIED
                     LNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICSECGHKD
                     GKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
                     /name="tnpB"
     gene            complement(4645..5049)
                     /gene="tnpA"
                     /locus_tag="JCP87_RS16160"
                     /old_locus_tag="JCP87_16160"
     CDS             complement(4645..5049)
                     /gene="tnpA"
                     /locus_tag="JCP87_RS16160"
                     /old_locus_tag="JCP87_16160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="WP_002287522.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERISE
                     SYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKEMF
                     WSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
                     /name="tnpA"
     gene            5355..6044
                     /locus_tag="JCP87_RS16165"
                     /old_locus_tag="JCP87_16165"
     CDS             5355..6044
                     /locus_tag="JCP87_RS16165"
                     /old_locus_tag="JCP87_16165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_060806731.1"
                     /translation="MAFYLPYLLIFVSISGSIWLIYKIFQTRYSLKGSKIRFKRFFFLG
                     CIFSLIIVSSGLFGVLEGNKRVSRSILLGNVTQKYESARDKKKKEQVLAQKIEKFTACY
                     EDMNDIFVKQEKRLTDKNMETLTRLYRNLPEEQQKEYQEKYEQVKKDVQYVKDTKVEEA
                     CSDLFGDTIPFSTSEQERKERQQSVTYERYEILLQQAINIQNLTKKETALNYLKSVKEW
                     LDQQQQN"
                     /name="hypothetical protein"
     Typing          2..933
                     /name="rep_cluster_1249"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atggcaaatg aaatcgtaaa gtatgaacca gaattaaata ccattccttt aagaaaattt
       61 accccaatag aaatgaactt gtttttttct attgtctcta gaatgcgcga taaaggtaat
      121 caaaaaatac gcttttattt cagccaactt aaagatttaa gtgcgtataa gcagactgca
      181 ggagaagtct ttataaaaga tttggcaaga acatacgatc atttgatgga tttacgtttc
      241 ggaagaaaaa gcaatggtgg attaacaata gaacgattta caatgtttac tgattttgaa
      301 attcatggag aagtcgataa cccttatgta gatataaaag tccacgaaaa agctttgcct
      361 ttacttaata atctagaaag ctgggtacgt ttctctttaa cagaatttcg agatttaaat
      421 agcagttatg ctaaaacaat gtttagattg ctaaaacaat accgaactca aggatgggct
      481 gaattttcta aggaagattt tttagagcta ttagatattc ctaaaagcta tagacaaaca
      541 aatataaatc agtttgtact caaaccaata aaagaagaac taactccact atttaaagga
      601 ttaactattc gtaaaaaata tggtaaaggt cgaggtaaac ctgttattgg ttatcgtttt
      661 acttggaaag ctgaaatcaa ccatgctgac gatttttcaa aagggaagca agaagattta
      721 cgtataaaat tatttaatat tgaacacaat ggagaattaa cacaaaaaga aaaatggcgt
      781 gctaaagatc gaatactaaa tcttccgtta ggtactcatg aagctgattt taaaaaacaa
      841 caacaaaccg aaaaagaaga agcggaaaaa caatcaatct caaatgagct taaacaagat
      901 ttattagaaa acttacaaaa cttattcgat tgaagcataa ggagtattta tgatagataa
      961 aacgatcaaa gaactcgcgg aagaatttca tgtttcaaaa caagcaatta ggaaaaggct
     1021 atcagctgat tttagagaaa actatgtgca aactgttact aggaacggag tgaaaacctt
     1081 agttgtcagc tacaaaggat atttgctttt aaaacaacat tttttaggta gtaacaccac
     1141 tggtaaccaa gtagaaaccg ttgctagtaa cgatgaaaac tcgattattg tttttttaca
     1201 tgaacagctc caagaaaaag atactcaaat aaaacaaatg caaaagttac tcgaccagca
     1261 acaacaactc accttgcagg caaatcaaca gatcgaaaaa ctgcaagaac agttacaatt
     1321 agcttatacg gaagaacctg aagaagagga attaacttct gtcaataaag aaaacaacaa
     1381 tgcaataaca acagaaaaaa agtggtggaa attttggtaa caattaccaa ctttccataa
     1441 agaagaaatc aatttctata gactctatct ttctaagaat aaaaaatatg tttaggtgat
     1501 caaatgacta taagtaaagt aatcaaacaa aaaagaatag aaaaacaact aactcaagaa
     1561 gatttagctg aaatgctttt agtatctaaa aaaaccattt ctaattggga aaatggtcga
     1621 acaataccag atacagaaaa tttaattcag tttgctaagt tatttgattt atcactagac
     1681 aatattttgt taggagaaga aaaaattatg gtaaaaaatc atacaaaaac actaatacta
     1741 ttatttcatt ttgtaatttt tttaagttta gttttcacct taattcagtc cggattcttt
     1801 tattttagcc attcaattgc cacttggtta ttaatatttt ttctaagttt actattaata
     1861 attaatactt taattattat ctttaataaa catagaaact tatttcttca cagcatattt
     1921 ccaattgttt tattaatttt tctatacttt atataaaaag atagaactat ttagtaagat
     1981 aaaaaagtag ctaattgtaa ttttcgtcta aaactcaaaa ctagtaaaaa taactttatt
     2041 gtgttatttt tatttataaa ttatgaaaaa ggacctttcg aaatgaaaaa taatagaatc
     2101 tacaaaaatc agttgaatta tgggctttta ttgccagttt ttctgctatg tatcattgga
     2161 ttactttctt tatatgttgc tttatatcac gactcttaca ctaattcaaa aatcacaaaa
     2221 gaattaatta aacaagtatt gtggtatagt attgggttca cttcagcaat aactatttat
     2281 ttttttaatc ctaaaatttt gtggaaatta actcctatat tttacggatt atgcatcata
     2341 atgttattac ttctcttgaa attctataat ccacaattag cagtcttaac tggagcaaaa
     2401 aattggtttt atattgctgg tttttcgttt caacctactg agttagtcaa aataggatac
     2461 acccttatgc tagctaaaat aaccgtcaat tatcagcaaa aatctattac tagtaatacg
     2521 aaagatgatt ggatttattt acttaaaact tttattgcta ctcttccaat aggaatatta
     2581 ttattttttc agaacgatct aggaacaatg ttagtcttca ttgttattta tatttttatt
     2641 ttgtttacgt ctaacataaa tataaaaata attgccccaa taatcgccat tggtgttgtt
     2701 ttatccttaa tatttttata tttggttata tcagatacag gaagagattt cttattaaaa
     2761 ataggatttc acgactatca gtttaaaaga atagactcat ggttgaatcc atttttagat
     2821 ccaaatggat ctagctatca gttagcaaat agtttaattg ctattggctc tggcggactt
     2881 ttaggtactg gttttaatgt atcaaacatt cacgttcctg ttagagaatc cgatatgata
     2941 ttttctgtaa ttggagaaaa ttttggcttt ataggaagtt gtcttgtaat attcctatac
     3001 ttttatttaa tttatcaaat gtataaaaca tgttttaaaa gcaataactt atttttcacc
     3061 tatatcggta taggcattgt tgcaatgatt ttttttcatg tttttgaaaa tataggtgca
     3121 agtatcggat tactacctct aactggtatt ccactcccct atattagtca aggtggttct
     3181 gccattctta gtaatttttt ggggttggga tttatgttgt gttgtagtag atatactaac
     3241 gaaaaaaaag gaacacaaaa atgaattcaa aataacactt tatgaataga atgtctattt
     3301 caataaaaat tatgataccg tgaactactc accacttagc taaacctgac ggttcttaac
     3361 gcttgaagtg ggagcttctt gggaatagag catacttgat agcgtatttc tttactaaca
     3421 gcggtgtctc ttatttacca agctatcccc gtagttccta cggttcttga tgattggatc
     3481 taagccaatc ccatagaatg tagtcttaga ccttcggtca gaatattgat actagcattg
     3541 atatcacgat catgatgagt atgacaaaca ggacaagtcc attctcgaat ttcaagagat
     3601 ttcttgccat ctttatgtcc gcactctgaa caaatctgac tagacggaaa ccatttatct
     3661 actttgatga tttttcgtcc ataccagtca gccttgtatt gtaatttagt cacaaacttt
     3721 gaccaagaaa catcagaaat acttttagct aatttatgat ttcgcaacat accttttgtg
     3781 tttaagtctt caatacagat aatatcgtga tttttgatca tttctgtact caacttattc
     3841 agaaaatcag tacgttgatt cattactttt tcatgcaatc tagctacttt gcgtttttgt
     3901 ttttgataat ttttagcttc aaatagattg gtacctttat ttttagccaa taaagcacgc
     3961 ctagacaatt tgcgttgttc acgctttagt ttcttttcca ttttggacgt gaatttatta
     4021 ttatcaattt tttgtccatc agaaagaatc gcaaagtcca taatacctaa gtcaatacca
     4081 attgtggaat tagttttagg taattcgata atttcttctt tacacaacaa agaaatatag
     4141 tatttaccgc tagaatgacg tgatattgta gcagatttga taatcccttt tggttgtcta
     4201 tgaagcttaa ttcttactaa tgacttcaat ttaggaactt tgatgaattt actatcaatc
     4261 aaagcaactg taccattttg attattcgtt gtataactct gaacaggatt tttcttactt
     4321 ttgaaacgtg gaaatccaac ggatttatcc cgaaaaaaat tcttgtatgc tttatctaaa
     4381 ttaagttggg cattggctaa agcaaggcta tcaatttctt tcaaaaacgg aaattctttc
     4441 ttgtatttag ctggtgtcgg aaaagtcatt tttttagaag aatcattttt aacttcttca
     4501 tacgcctttt ttcggtcatc aagcattaga ttgtagacct tacggacaca accaaaagat
     4561 ttggcaaaga agatttcttg ttcctctgtt ggatagattc tgaatttgta tgcttttagt
     4621 tgttccataa agttcaccta ctttctattt atgattgttt ccttgatttt ggatatactt
     4681 cttaatcaca tcaattggtg cgccaccagt tgtcagaaga caaaaacttt tagaccagaa
     4741 catttctttc caaagaaatt gtttgactct tggaaagtca cgttttatca atcttgagct
     4801 ggcactttta taggcattga tgaattttgt caattctgtt ttaggttgag ctttgaacat
     4861 aatatgaacg tggtctttat catgattcca ctccactaaa gtaatgtgat acgattctga
     4921 aattctttca aaagtagttt tggcataatc agatatttca tcatcaatca cttgtctacg
     4981 atatttcgtt actaaaacaa ggtggtaata aagaagaaat actgaatgat tatttgtatc
     5041 taattccatg ttatatcaac tcatttcttg tatagactga ttgtaacatg gaacaaaata
     5101 aaaaggcaat acgccttagt tgtcggtctt cgagttacca acggtaaccc tcataccgaa
     5161 cggcattcat cacccaccta tagaggatgg gcgacttctg cctaattctg ttaaaaaact
     5221 ccatcaagag ctattagacc agcgaaataa ggaacagaaa aaggtgctta ttcaacgatc
     5281 attggatttt cttgccccct tatgttgctt agtcctgaca ctgttcgcat tttggttagt
     5341 atggggaggc taaaatggca ttttatttac cctatctact catttttgtt agtatttcag
     5401 gaagtatttg gctcatctat aaaatttttc aaacaagata ttcattaaaa ggctctaaaa
     5461 ttcgatttaa gcgatttttc tttcttggct gtatattttc cttgataatc gtttcaagcg
     5521 gcttattcgg cgttttagag ggaaataagc gcgtttctag aagtatttta ttaggaaatg
     5581 tcactcaaaa gtatgaatca gcgcgtgata aaaagaaaaa agagcaagta ttagcacaaa
     5641 aaatagaaaa atttaccgct tgttatgagg acatgaatga tatttttgtg aagcaagaaa
     5701 agcgtttgac ggataaaaat atggaaacac tcactcgact ttatcggaat ttgccagaag
     5761 aacagcaaaa agagtaccaa gaaaaatatg aacaagtaaa aaaagacgtg caatatgtga
     5821 aagatacgaa agtggaagaa gcttgtagtg atttatttgg agatacaatt cctttttcaa
     5881 ctagcgaaca agaacgaaaa gaacgacaac aatcagtcac atatgaacgc tatgaaatct
     5941 tgcttcaaca agcaattaac atacaaaatc tgactaaaaa agaaacagct ttaaattatt
     6001 taaaaagcgt caaggaatgg ttagatcagc aacagcaaaa ttgaatttga ttgaaattca
     6061 tgttaaacta aacatgcaaa tgttcaaaca ttagatacac gaaagcccca gagaggtcgg
     6121 attctctggg gcttttttta ggttgatgtc gcctttactg attttacttc ttgtttcggt
     6181 tattcaacca ataactgaat acagagatac aaactcctac aagaaggggg caaataaaca
     6241 gttcaaacat cagatacacc tccttccagt cgcaagactg tcggataggc gacaagttat
     6301 tataccctac aaaattaaat ctgtgtggca attttaagta tctcttattt ccgggttgtt
     6361 agggcttgcc ctgaccgcct gtagggcgct ttaaatgcca gataaaggtt tttatactaa
     6421 gactgtctta aaacggctta gacaagctct tagagcctca accctccttt ttgaacaatg
     6481 gttttagcaa aggagctgga ggcgactgcg caggtataat gtgagagcgt agcgatcaca
     6541 cctttttggc gaccgtaggg agcgaggttt tgaattagca gtttagaaaa gttcgcgaac
     6601 ctgtttaaag aaaaaataat tgttttttta ggtgggaaat tttgtctccc tcttttataa
     6661 tcttttttta aacctctttt taaacctctt taccgtcggc tgtgtcctta ctcccccaag
     6721 ggatacaaaa ttttataggc atgaaattat ctgtttatag gcatgaaatt atctgtttat
     6781 aggcatgaaa ttatctgttt ataggcatga aattatctgt tttaggtatt gtttttagac
     6841 ataatatgtc ctaaaatgat gtcaataaaa tcatttagac tggagtaaca actaa
//
