LOCUS       NZ_CP066373            28218 bp    DNA     circular CON 03-APR-2024
DEFINITION  Staphylococcus epidermidis strain PH1-28 plasmid pSE3, complete
            sequence.
ACCESSION   NZ_CP066373
VERSION     NZ_CP066373.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN16085533
            Assembly: GCF_016406625.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus epidermidis
  ORGANISM  Staphylococcus epidermidis
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 28218)
  AUTHORS   Hilaire,P., Landemaine,L., Contreras,S., Blanquart-Goudezeune,H.,
            Siguier,P., Cornet,F., Chiapello,H., Loux,V., Clavaud,C. and
            Morand,S.C.
  TITLE     Complete Genome Sequence of Staphylococcus epidermidis PH1-28,
            Isolated from the Forehead of a Hyperseborrheic Donor
  JOURNAL   Microbiol Resour Announc 10 (9), e00165-21 (2021)
   PUBMED   33664152
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28218)
  AUTHORS   Morand,S.C., Contreras,S., Hilaire,P., Blanquart-Goudezeune,H. and
            Clavaud,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-DEC-2020) Advanced Research, L'Oreal, 1 Avenue Eugene
            Schueller, Aulnay-Sous-Bois 93600, France
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: NOV-2020
            Assembly Method :: MaSuRCA v. v3.3.0; SPAdes v. v3.10.1; CANU v.
            v2.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 4828.0x
            Sequencing Technology :: Oxford Nanopore MinION; Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016406625.1-RS_2024_04_03
            Annotation Date                   :: 04/03/2024 04:47:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,504
            CDSs (total)                      :: 2,420
            Genes (coding)                    :: 2,334
            CDSs (with protein)               :: 2,334
            Genes (RNA)                       :: 84
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 54 of 86
            Pseudo Genes (incomplete)         :: 39 of 86
            Pseudo Genes (internal stop)      :: 39 of 86
            Pseudo Genes (multiple problems)  :: 35 of 86
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP066373.1.
            Bacteria and source DNA available from L'Oreal Advanced Research.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..28218
                     /organism="Staphylococcus epidermidis"
                     /mol_type="genomic DNA"
                     /strain="PH1-28"
                     /host="Homo sapiens"
                     /db_xref="taxon:1282"
                     /plasmid="pSE3"
                     /geo_loc_name="France"
                     /collection_date="2012-06"
     gene            534..2384
                     /gene="tdc"
                     /locus_tag="ICN77_RS00020"
                     /old_locus_tag="ICN77_002459"
     CDS             534..2384
                     /gene="tdc"
                     /locus_tag="ICN77_RS00020"
                     /old_locus_tag="ICN77_002459"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829536.1"
                     /GO_function="GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="WP_002503027.1"
                     /translation="MKRKDDINLHALFIGDKSENGELYKDMLINLVDEHLGWRQNYMPQ
                     DKPVISSHEKNSDSYLNTIEHMKEVMNEISSRMRTHSVPWHSAGRYWGHMNSETLLPSI
                     LAYNFAMLWNGNNVAYESSPATSQMEEEVGYDLAKLMSYNNGWGHIVADGSLANLEGLW
                     YARNIKSLPLAMKECAPSLVETKTDWELLNMSTQEIIDLMEKAEDKIDDLKQYSARNGK
                     NLQSLGKWLVPQTKHYSWLKAADIIGIGIDQIVSVPVDSSYRMDIDELEKIIRKLVNEG
                     TPILGVVGVVGSTEEGAVDSIDKIVALRDKLFNEGIYYYIHVDAAYGGYARSIFLDEDN
                     NFIPFNDLQKVHHEYGVFTENTEYITKEVYEAFKAIELTESVTIDPHKMGYVPYSAGGI
                     AIKDIRMREVISYFATYVFEKNAEIPALLGAYILEGSKAGATAVSVWAAHHVLPLNITG
                     YGKLMGASIEGALRFYDFLNTQSFKVGDKEIELYTLTRPDFNMVDYVFKEKGNNDLVSM
                     NELNHSFYEQASYVSGNIYGNEFITSHTDFAIPDYGNSPLSFVESLGFNKEEWARAGKV
                     TILRAAVLTPYMNDKEKFEEYAPKIKAAIQDKLEKIYKIK"
                     /name="tdc"
     gene            2422..3861
                     /gene="tyrP"
                     /locus_tag="ICN77_RS00025"
                     /old_locus_tag="ICN77_002460"
     CDS             2422..3861
                     /gene="tyrP"
                     /locus_tag="ICN77_RS00025"
                     /old_locus_tag="ICN77_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829533.1"
                     /GO_function="GO:0070908 - tyrosine:tyramine antiporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-tyramine antiporter"
                     /protein_id="WP_001829533.1"
                     /translation="MSSQHKIALSTFIGLTMALCATVRSIPTLAAAGWTLLVYIIFAVL
                     FFAAPIAFISGELSTMLPQEGGPQLWVKTALGNKWGFVVAWLLWVQMFPGMVMVASTLG
                     PLLGNTFGNVPLGNNHWFILGCILIIYWIITFLNLKFDMAKVGGNIGVWLGVYIPVLVI
                     FIMGAFALSKVGIVSHGYLGSFSWSKVVPNLQNMETFKYLAGIMFIFVGIEMSSVFMPR
                     LKDATKNYTKGVFISLIGLVLLNLVNAALVANVVPNGKMELSNITQPILIYCHILGLPT
                     IIANIFSFMVFIGVLLQLSAWVTGPSKTIIQVARDGFLPPKFNFHRQNEYGVSRNVVLT
                     QSIIISLFALLYGVMEDVNTVFLTLTNATTIIYSIVYVLIAVALIKLRVDQPDTPRPYR
                     IGRKGNGKAYTVATVLILSILIVVITTLISSTWIIGVLVSLITIVMFVIPLLINNVKKD
                     MWLTETQKDLELYGDNANNED"
                     /name="tyrP"
     gene            3990..5375
                     /gene="nhaC"
                     /locus_tag="ICN77_RS00030"
                     /old_locus_tag="ICN77_002461"
     CDS             3990..5375
                     /gene="nhaC"
                     /locus_tag="ICN77_RS00030"
                     /old_locus_tag="ICN77_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829554.1"
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]; GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="WP_001829554.1"
                     /translation="MNAKKSETKKVSFVESLIILLLLLAILGYLIIFQKLSPHVPILFV
                     FMILLFYGRIRGFSWDEIQSGIISGISSGIVPIIIFILIGVLVSTWIMSGTIPTIMAYG
                     FKIISVKFFLPTVFIVCSLVGITVGSSFTTISTMGIAFLGIGHILGFDNAITAGAIVSG
                     AFLGNNISPLSDTTNLAASIGEVNLFTHIMNVMWTAIPGFIISFLGYMFIGTPNGNANL
                     NSLNDMIKTLNSSFHISVITLLPLVFLFLFAWKKVPAIPTLLVGSTIAIILSIINEPSL
                     NIQKISNTIMNGYIANTGDQSLDNLLSRGGIMSMLGSACLIILALALGGLLIKFEIVST
                     LINKIKDFVNNAPKLIGLTTLSSIMINILVGEQYLSIILPGKTFKDSFDSIGLSKKYLT
                     RTLADAGTAVNAIIPWGVSGTFIMGALKVSTLAYFPYAFFPLLCPIITIILGLTLKTKK
                     YKV"
                     /name="nhaC"
     misc_binding    5425..5635
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5691..6944
                     /gene="tyrS"
                     /locus_tag="ICN77_RS00035"
                     /old_locus_tag="ICN77_002462"
     CDS             5691..6944
                     /gene="tyrS"
                     /locus_tag="ICN77_RS00035"
                     /old_locus_tag="ICN77_002462"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829539.1"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="WP_001829539.1"
                     /translation="MNIIDELQWRDAINQQTNEEGLRELVENNSISLYCGVDPTGGSMH
                     IGHLIPFMMMKRFQLAGHKPFILIGGATGTIGDPSGRTSERMLQTLETVQENVEGLSSQ
                     MKKLFGKDANVTIVNNYDWLSSLTLLDFLRSYGKDFNINTMLAKDIVASRLDKGISFTE
                     FAYQILQSIDFLHLFKNHNVQLQIGGADQWGNITSGLDLIRKKEGNDAKVFGLTIPLML
                     KADGTKFGKTAGGAIWLDPKRTSPYEFYQFWLNQDDRDVIKYLKFFTFLDKEEIDFLEE
                     KVKNEPEKREAQKRLAEEVTKFVHDEAALQEAQKITQALFSGNVKDLTVKEIEQGLQNM
                     PSFNTTNKTKNIVDWLVEINCEPSKRQAREDVINGAININGEKVTDINFLVNPNSAFEG
                     KYMIIRKGKRNYFLVKVL"
                     /name="tyrS"
     gene            complement(7086..7766)
                     /locus_tag="ICN77_RS00040"
                     /old_locus_tag="ICN77_002463"
     CDS             complement(7086..7766)
                     /locus_tag="ICN77_RS00040"
                     /old_locus_tag="ICN77_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002440810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_002503026.1"
                     /translation="MKSMKEIADELNVTKMTVYNNAKKANVKFQKIDNVNYLTSEDEII
                     VINRIRKNQNKNDDFESEKKEEPNNDNLVKDETIKQLYNQIDIYKEQSNRDKEQINTLN
                     RLLENQQVLALESNKKIKKLEDQLEEERRLNYSFDTSVNERQNVNVQEATFTGESKDTD
                     QQQEWEQPTEVQHKDIPEEKENENLNEEPSTIDDKQFEEIDNEYEDKEEKPPKKGFWSR
                     LFGN"
                     /name="DUF536 domain-containing protein"
     gene            8262..9233
                     /locus_tag="ICN77_RS00045"
                     /old_locus_tag="ICN77_002464"
     CDS             8262..9233
                     /locus_tag="ICN77_RS00045"
                     /old_locus_tag="ICN77_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002440813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_002503037.1"
                     /translation="MSNFNIKEIQKEKFYQLPKVFFTNPKYTKLSNDAKITWSILRDRL
                     DLSIRNNWVDENGDIFFIYTNEKLKSILNISSPNKLSKIKKELTEADLFNQIRVGLNKP
                     NKLYIKKPEVTEADVYYISQQENDIEQHNNTDVSLSYVQKYDNDTSRNINMIHHDISKE
                     YTNDTDLSNTDYIETENNDTYDMNDTYNNQTNHNHSDHTNYQQSEFNNDALKFQVLEEL
                     PQQIKDYLSNFEIREIRIIKSVLLKGKKSFNNTLNTYYRLEDVEFELVSVLKRFKAMLL
                     QKNETVEAMQGYLMQSIKAELEEIHTLNMRRQNMKKHNIFNQ"
                     /name="replication initiator protein A"
     gene            <9250..9543
                     /locus_tag="ICN77_RS12465"
                     /pseudo=""
     CDS             <9250..9543
                     /locus_tag="ICN77_RS12465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001568503.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(10120..10902)
                     /locus_tag="ICN77_RS00050"
                     /old_locus_tag="ICN77_002465"
     CDS             complement(10120..10902)
                     /locus_tag="ICN77_RS00050"
                     /old_locus_tag="ICN77_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002817982.1"
                     /GO_function="GO:0019152 - acetoin dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0045150 - acetoin catabolic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetoin reductase"
                     /protein_id="WP_002503036.1"
                     /translation="MKSENKVAIITGSAGGLGKAIAERLANDGFNIVVQDINNELLLET
                     ETEFKEKGYNVISFKSDVSKQKEQEELVNFAVKEFNQLDVFVNNAGVDAVTPFLEINEN
                     QLNKLFNINVFGTVYGTQAAAKQFIKQNTKGKIINACSIAGHESYEMLGTYSATKHAVR
                     SYTQVAAKELAKYKINVNAYCPGVAKTKMWDRIDEEMVKYDENLKPGDAFKEFSSAIKL
                     GRYQEPKDVANLVSFLSSEDAEYITGQSILTDGGLVYR"
                     /name="acetoin reductase"
     gene            complement(11050..12120)
                     /locus_tag="ICN77_RS00055"
                     /old_locus_tag="ICN77_002466"
     CDS             complement(11050..12120)
                     /locus_tag="ICN77_RS00055"
                     /old_locus_tag="ICN77_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002503035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002503035.1"
                     /translation="MESYDLYEKKYNYYKELLSLSYSDAVQSLIEKHGEVVDNYYKEKS
                     YNKFLNGEIKRIAYGKYTKTKEGLYCHHILENEYENISNKEYIAHYKYPYEYHHKENLV
                     YCDLIEHLILHALITKETNGDRGFKGLVEFLIPTAEEWYIDGYEPRVLWMQLCRERAFL
                     SEEYTEKLLSDVDELLKDVQVYQELLEEIREEELRKLEHEDRLRQMIEQQELEDEERIQ
                     RHMQNLNISREEYENNEDLIKEEAHRYINKDSIFELKISKKTPRKEVLELLQHYEELYD
                     SSKFYSDEYASSKLNIVKDDLIEELRELSKKVELKLENAKYYKKDGNYNIKVRKGLSFE
                     VTPESANIIIDGKRLQ"
                     /name="hypothetical protein"
     gene            12365..13039
                     /locus_tag="ICN77_RS00060"
                     /old_locus_tag="ICN77_002467"
     CDS             12365..13039
                     /locus_tag="ICN77_RS00060"
                     /old_locus_tag="ICN77_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105987.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(13444..13632)
                     /locus_tag="ICN77_RS00065"
                     /old_locus_tag="ICN77_002468"
     CDS             complement(13444..13632)
                     /locus_tag="ICN77_RS00065"
                     /old_locus_tag="ICN77_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002440614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="WP_002440614.1"
                     /translation="MSEEKFEQAKGNIKETIGDATDNKDLKAEGKGDKASGKAKEVVDD
                     VKDKANDLIDKVKGDKN"
                     /name="CsbD family protein"
     gene            complement(13824..14498)
                     /locus_tag="ICN77_RS00070"
                     /old_locus_tag="ICN77_002469"
     CDS             complement(13824..14498)
                     /locus_tag="ICN77_RS00070"
                     /old_locus_tag="ICN77_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105987.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            14862..15806
                     /locus_tag="ICN77_RS00075"
                     /old_locus_tag="ICN77_002470"
     CDS             14862..15806
                     /locus_tag="ICN77_RS00075"
                     /old_locus_tag="ICN77_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002440612.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="WP_002440612.1"
                     /translation="MSRKEQEIHSKQSTLQEVTNYTSTGYSNSRLGVHSVHPQNPKLSF
                     DAMTIVGNLSRDNAQKLSSFMSIEPQIRLWDILQTKFKAKALQEKVYIEYDKVKADTWD
                     RRNMRVEFNPNKLTHEEMLWLKQNIINYMEDDGFTRIDLAFDFEDDLSNYYAMTDKAVK
                     KTVFYGRDGKPETKYFGVRDSDRFIRIYNKKQERKDNADVEVMSDHLWRVEIELKRDMV
                     DYWNDCFNDLHILKPDWTSPEKLNEQAMVYMLIHEEDKWGELNKRTKYKYKNLIKEISP
                     VDLTELMKSTLRENEKQLQKQIEFWQTKGKKLF"
                     /name="replication initiation factor domain-containing
                     protein"
     gene            16452..17126
                     /locus_tag="ICN77_RS00080"
                     /old_locus_tag="ICN77_002471"
     CDS             16452..17126
                     /locus_tag="ICN77_RS00080"
                     /old_locus_tag="ICN77_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105987.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            <17187..17336
                     /locus_tag="ICN77_RS12470"
                     /pseudo=""
     CDS             <17187..17336
                     /locus_tag="ICN77_RS12470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002494364.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein Rep"
                     /name="replication protein Rep"
     gene            17442..17585
                     /locus_tag="ICN77_RS00085"
                     /old_locus_tag="ICN77_002472"
     CDS             17442..17585
                     /locus_tag="ICN77_RS00085"
                     /old_locus_tag="ICN77_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002467993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002958656.1"
                     /translation="MSNKYNIHPALYIGGFAVFFSFIFGFPVGTLMGLAIGIGVSKKNK
                     NL"
                     /name="hypothetical protein"
     gene            complement(18111..18476)
                     /locus_tag="ICN77_RS00090"
                     /old_locus_tag="ICN77_002473"
     CDS             complement(18111..18476)
                     /locus_tag="ICN77_RS00090"
                     /old_locus_tag="ICN77_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020368092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002494365.1"
                     /translation="MKWLKIIILILSLVPIEFIGLFTDYQTGLLIGYIPFIIVAILISR
                     SIFKFGLKNNISIIISRCIGTFLSWECVHWFMNIYDSSDYFKPLTTDIFALFLGAIHFI
                     VIMLIYLVIYGFSHRNN"
                     /name="hypothetical protein"
     gene            18540..18930
                     /locus_tag="ICN77_RS12475"
                     /pseudo=""
     CDS             18540..18930
                     /locus_tag="ICN77_RS12475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015310584.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF334 domain-containing protein"
                     /name="DUF334 domain-containing protein"
     gene            19058..19282
                     /locus_tag="ICN77_RS00110"
     CDS             19058..19282
                     /locus_tag="ICN77_RS00110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002500874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_080034836.1"
                     /translation="MLVKISERIKKGGFILKIVLFFTYYFVSCFILSSLCDLLLSTKFD
                     VYINVIAALIFAVCMTPLTFILKDDKNKK"
                     /name="hypothetical protein"
     gene            complement(19599..20336)
                     /locus_tag="ICN77_RS00115"
                     /old_locus_tag="ICN77_002478"
     CDS             complement(19599..20336)
                     /locus_tag="ICN77_RS00115"
                     /old_locus_tag="ICN77_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002470105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiX/YebB-like N1pC/P60 family cysteine
                     hydrolase"
                     /protein_id="WP_049389762.1"
                     /translation="MKKLMMSLLCCTVLTTGNVNAQGDSSTNSESLKELQNEGIVSKSI
                     TEQQWQQMKAQERKDEAEFEKTAEVQWQKQQKQDRIDRENRSRKKKFHLKKGDFFITNN
                     VSSKGFTGHAAIYIGKGKVKEAPGYGKPVRVKSFSNWKKSTLKKRKGSPKHRYIKVYRA
                     PKKYRGKAGSYAKSHFNGVPYSITTNPYSKSVTYCSKLVWQSYYYGAGRLSVLPVVTSQ
                     FIIEPYSLNQYIPSKAVRSYKRS"
                     /name="YiiX/YebB-like N1pC/P60 family cysteine hydrolase"
     gene            20454..20849
                     /locus_tag="ICN77_RS00120"
                     /old_locus_tag="ICN77_002479"
     CDS             20454..20849
                     /locus_tag="ICN77_RS00120"
                     /old_locus_tag="ICN77_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002502726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="WP_049389761.1"
                     /translation="MKRKYKIIGIIFIVLLIVLTLIFSIVHHYANVQKHEEAKLRQKVH
                     HIFKQKGWEDKVKEEQNIFTFNTGDNDLQVTFKDEPYNTYTYSIDENNKVYGNAVLKDE
                     YDKDFDSKKKYKEYLRKMHFEEKYDLK"
                     /name="DUF3139 domain-containing protein"
     gene            complement(20890..21297)
                     /locus_tag="ICN77_RS00125"
                     /old_locus_tag="ICN77_002480"
     CDS             complement(20890..21297)
                     /locus_tag="ICN77_RS00125"
                     /old_locus_tag="ICN77_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002958643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_198895598.1"
                     /translation="MPKKQNSKEKILTIRVSQSQYEKICELADIREMNVTEYIRHTAIG
                     NRIKPTVIEQIKESSEVSELFKKDNEALKSNNQELQQHIHQLEDEIDQLRQENDVFHHL
                     LQHFDSTAFFNFNTYRDDRQLKNAIKRLKEQ"
                     /name="hypothetical protein"
     gene            21752..22960
                     /gene="mobV"
                     /locus_tag="ICN77_RS00130"
                     /old_locus_tag="ICN77_002481"
     CDS             21752..22960
                     /gene="mobV"
                     /locus_tag="ICN77_RS00130"
                     /old_locus_tag="ICN77_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002958641.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /protein_id="WP_198895600.1"
                     /translation="MKLAWNTQKNKMSDVKGKEMEQERKGRIKNDEIDLKRTNLNFDLV
                     EDERHLYHRVKDRIEYYKKQGSRVQKNSVVMYSNIITLSKEEADRMGETRTKHYFKTCK
                     DYFSERFGEANVVSAKVHMDESAPHMHLHFIPVNHQGRLSARTAMNRQAINHIHDELTT
                     HLCQQGFDVERGSTDDNKTYIQDIHEYKKKAKVLSELDQQIETKKQLLRDINDLHDEKE
                     NLTRDIQNLKRKNHFLQEDSQQAQEDIDLYKQLRTISRDDFKKEEEKYQKEIKAYEASL
                     SGLRMNYRDLDKRNQHLTTQNNQLEHHLDMLNARHQAMNDMVRNDTRILFAGLRCALKD
                     MNIELSAEIKYQRMPEVGIDPDTVDQGALTHAYQGGVSGIDHHIRKASSPIKKEAENDL
                     ELE"
                     /name="mobV"
     gene            complement(23717..23872)
                     /locus_tag="ICN77_RS00135"
                     /old_locus_tag="ICN77_002482"
     CDS             complement(23717..23872)
                     /locus_tag="ICN77_RS00135"
                     /old_locus_tag="ICN77_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002498916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class phenol-soluble modulin"
                     /protein_id="WP_002455859.1"
                     /translation="MEHISKLGEAIVNTISASQSGDSAELAKSIVDIAANGIGVISDVA
                     KAFGLM"
                     /name="beta-class phenol-soluble modulin"
     gene            24302..>25066
                     /locus_tag="ICN77_RS00140"
                     /old_locus_tag="ICN77_002483"
                     /pseudo=""
     CDS             24302..>25066
                     /locus_tag="ICN77_RS00140"
                     /old_locus_tag="ICN77_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020360739.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /name="RepB family plasmid replication initiator protein"
     gene            25129..25803
                     /locus_tag="ICN77_RS00145"
                     /old_locus_tag="ICN77_002484"
     CDS             25129..25803
                     /locus_tag="ICN77_RS00145"
                     /old_locus_tag="ICN77_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105987.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            25837..26346
                     /locus_tag="ICN77_RS00150"
                     /old_locus_tag="ICN77_002485"
     CDS             25837..26346
                     /locus_tag="ICN77_RS00150"
                     /old_locus_tag="ICN77_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011251335.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_198895604.1"
                     /translation="MFFYFATEPKIEIYTKNILKETHANNKKRNELKTLLNSKLVFGDT
                     LYITDLCIIADSTKHLVDILDLLSAKGISLYIINLNKNLIADTNENFIKTLHEITDFQS
                     DIVKFRTRMGLENYTREGKRLGRPKRDDKNLRDAIEMYMSKKYTLDEIKEKTNISRATL
                     YRHLDK"
                     /name="recombinase family protein"
     gene            26814..27392
                     /locus_tag="ICN77_RS00155"
                     /old_locus_tag="ICN77_002486"
     CDS             26814..27392
                     /locus_tag="ICN77_RS00155"
                     /old_locus_tag="ICN77_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_002455810.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNQYGCEKIFSDHISGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNNRGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLKLLKTLYDNGTPI
                     KTIAEQWKVSRTTIYRYLNKLNNQENKDK"
                     /name="recombinase family protein"
     gene            27519..28127
                     /locus_tag="ICN77_RS00160"
                     /old_locus_tag="ICN77_002487"
     CDS             27519..28127
                     /locus_tag="ICN77_RS00160"
                     /old_locus_tag="ICN77_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002436987.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_198895602.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEVINTVNYLKDKEVQLMITSLPMMNEVIGIPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQEQGIKVAKEKGVYKGRPLLYSANAKDPQKRI
                     IYHRVVEMLEEGKAISKIAREVNITRQTIYRIKHDKGEI"
                     /name="recombinase family protein"
     Typing          8263..9233
                     /name="rep_cluster_1110"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.538"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          9362..9547
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="94.118"
                     /coverage="99.0"
                     /evalue="1.32e-74"
     Typing          14959..15781
                     /name="rep_cluster_1118"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.204"
                     /coverage="97.0"
                     /evalue="0.0"
     Typing          24303..25004
                     /name="rep_cluster_1439"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.011"
                     /coverage="98.0"
                     /evalue="0.0"
     Typing          21681..22957
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="96.948"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 ttttgttaaa aagatatata tcatatagac aagaaaagga atatacaatt atactaacaa
       61 aaattgatat ttgttacact aatattacta ttctatacat aaagtagtaa accataacta
      121 ttcttcgtat ttcttttttc tttctaaaaa gttatttttt ggctctctac aaagaaagac
      181 gctcaatttg agtgtctttt ttcatattaa aagtaacttt aaaaaattaa gacagaaaca
      241 cttatattgt atcgttatct taagaagagg atttaaatag tgatatagcg atagaagaat
      301 aaaatgtaca aataattata gtgagggact atttagtaag ttattttata gtcaataaaa
      361 gagtatgtta atcatttatt ctttcagatt tttaataatt taattttata gtattcagac
      421 atgatccata aatcaatttt aattgttaac aaaaacttca cattttttat aactgtattt
      481 taccattttt tcacatcaag agtataatga aaaaggagaa aggagtttta attatgaaaa
      541 gaaaagacga tatcaatttg catgctttat ttattgggga caaatctgaa aatggagaat
      601 tatacaaaga catgctaatt aatcttgtag atgagcattt aggttggaga caaaattata
      661 tgcctcaaga taaacctgtc atttcaagtc acgaaaaaaa ttctgatagt tatctaaata
      721 ctattgagca tatgaaagaa gtgatgaatg aaatttcttc tcgtatgaga actcattcag
      781 taccttggca ttcagccggt cgatattggg gacatatgaa ctctgaaact ctattaccat
      841 caattctagc gtataatttt gcaatgctat ggaacgggaa taacgtagct tatgaatcat
      901 ctcctgcaac ttcacagatg gaagaagaag tgggatacga ccttgcaaaa ttaatgagtt
      961 ataacaatgg ttggggacac attgttgctg atggatcact agctaatctt gagggtttgt
     1021 ggtatgcacg aaatattaag tctttaccct tagctatgaa agaatgtgct cctagtttag
     1081 tagaaactaa aactgattgg gaattattaa atatgagtac acaagaaatt atagatttaa
     1141 tggaaaaagc tgaagataag atagacgatt taaagcaata ttctgcaaga aatggtaaga
     1201 acttacagag tcttggtaaa tggcttgttc cacaaactaa gcattattct tggttaaaag
     1261 ctgctgatat tatcggtatt ggtattgatc aaatagtttc agtgcctgta gattcttctt
     1321 atagaatgga tattgatgaa ctagaaaaaa ttataagaaa gttagtaaat gaaggaacac
     1381 ctattttagg cgtagttggt gtagttggct ctactgaaga aggtgctgta gatagcattg
     1441 ataaaatagt agcacttaga gataaattat ttaatgaagg aatttactat tatattcatg
     1501 ttgatgctgc atatggtggc tatgctagat ctatattctt agatgaagat aataatttta
     1561 tacctttcaa tgatttacaa aaagttcatc atgaatatgg tgtattcaca gaaaatacag
     1621 aatatattac aaaagaagtt tatgaagctt ttaaggctat agaattaact gagtctgtga
     1681 ctattgatcc tcataaaatg ggttatgtac cttattcagc tggaggaata gcaattaaag
     1741 acatccgtat gagagaagta atatcatatt ttgcaacgta tgtttttgaa aagaatgctg
     1801 aaatccctgc tttattaggt gcctatattt tagaaggatc caaagctggt gctacagctg
     1861 tttctgtatg ggctgctcac catgttcttc ctttaaatat tacaggatac ggaaaactaa
     1921 tgggagcatc tattgaaggt gctttaagat tctatgattt cttaaatact caatcattta
     1981 aagttggaga taaagagatt gaactttata ctcttactcg acctgatttt aatatggtag
     2041 actatgtttt caaagaaaaa ggtaataatg acttagtatc tatgaatgaa ttaaatcaca
     2101 gtttttatga acaagcttca tatgtatcag gtaatatata tggtaatgaa tttataactt
     2161 ctcacactga ttttgctata cctgattatg gtaatagtcc gttgagtttc gtcgaaagct
     2221 taggatttaa taaagaggaa tgggctagag ccggtaaagt aactatatta agagctgctg
     2281 tacttactcc ttatatgaat gataaagaaa aatttgaaga atatgcacca aaaataaaag
     2341 cagcaattca agataaatta gaaaaaattt ataaaataaa ataatcaaac ttaattattg
     2401 ctttaatgag gagtgtacaa aatgagcagt caacacaaaa tcgccttaag tacgtttata
     2461 ggtttaacaa tggcattatg cgcaacagtg cgtagtatac ctacattagc agctgcagga
     2521 tggacattac ttgtatatat aatttttgct gttctgtttt ttgctgctcc tattgcattt
     2581 atatctggag aactttctac aatgcttcct caagaaggtg gtcctcaact ttgggtgaaa
     2641 acagcgttag gtaataaatg gggatttgtt gtagcatggc ttttgtgggt tcaaatgttt
     2701 cccggcatgg tcatggtcgc ctcaacatta gggcccttac tcggtaatac ttttgggaat
     2761 gttcctttag gaaataacca ctggtttatt ttaggatgta ttttgattat ttattggata
     2821 ataacattct taaatttaaa atttgatatg gcaaaagttg gaggtaatat aggtgtttgg
     2881 ttaggggttt atatccctgt tttagtaatt tttataatgg gagcatttgc tttatccaaa
     2941 gttggaattg tatcacatgg ttacttaggc tctttttcat ggtctaaagt agttcctaat
     3001 ttacaaaaca tggaaacttt taaatattta gctggcatta tgttcatatt tgttggtatc
     3061 gaaatgtctt ctgtttttat gccaagatta aaagatgcta ctaaaaatta tactaaaggt
     3121 gtattcatct cccttatagg tttagtttta ctaaacttag ttaacgccgc tcttgtagcc
     3181 aatgttgtac ctaatggcaa aatggaatta tcaaacatta cacaaccaat attaatatat
     3241 tgccatattt tagggttacc tacaataata gctaatatat ttagctttat ggtgttcata
     3301 ggtgtattac tacaattatc agcttgggtt accggcccat caaaaacaat tattcaggta
     3361 gctagagatg gatttttacc tcctaaattt aattttcata gacaaaatga atatggtgtg
     3421 tcacgtaatg ttgtactaac acagtctata attatttctt tatttgcatt attatatggt
     3481 gtcatggaag atgtaaacac agttttctta acccttacaa atgcaactac aataatttat
     3541 agtatagttt atgtattaat tgctgtagct ttaataaaat taagagtaga tcagccagat
     3601 actccaagac cttatagaat aggtcgaaaa ggaaatggaa aagcctacac tgtagcaact
     3661 gttctaatat taagtattct catagtagtt attactactc taatatcttc tacttggatt
     3721 attggtgtat tagttagttt aattactatt gtcatgtttg ttataccatt actaattaat
     3781 aacgtaaaaa aagatatgtg gttaacagaa actcaaaaag atttagaatt atatggcgat
     3841 aatgctaaca atgaagacta aattaatata ttaaaaaaag ccattttgta ttagccactt
     3901 atattatgtt ttcaaaagta tatagtgggt ctattacaag atggctttta ttttttcaat
     3961 gtttttaatt taaaataagg ggagagttta tgaatgctaa aaaaagtgaa acaaaaaaag
     4021 tatcttttgt agaaagttta ataatactac tacttttgct agctatatta ggatacctta
     4081 ttatatttca aaaattgtct cctcatgtac ctatcctttt tgtttttatg attttgttat
     4141 tttatggtag gattagagga ttttcttggg atgaaataca aagtggtatt atctctggca
     4201 tttcttctgg tatagttcct ataataattt ttatattaat aggtgtatta gtttcaacat
     4261 ggataatgtc aggaacgatt cctacaataa tggcttatgg gtttaaaatt atctctgtaa
     4321 aattcttttt gccaactgtt tttatagtat gtagtttggt aggtataacc gttggtagct
     4381 cttttacaac tatttcaacc atgggtatag cttttttagg tattggccat atattagggt
     4441 ttgataatgc gattactgct ggtgcaatag tttccggagc ttttttaggt aataatatat
     4501 cccctttgtc tgatacaact aatttagcag caagcatagg tgaagttaac ttatttacac
     4561 atataatgaa cgttatgtgg actgctatac ctggatttat tattagcttt ctaggttata
     4621 tgtttattgg aactccaaat ggtaatgcta atttaaatag tcttaatgat atgattaaaa
     4681 cattaaatag tagctttcat atttccgtta taactttatt accattagtt tttctttttt
     4741 tattcgcttg gaaaaaagta cctgctattc caactttatt agtaggctca acaatagcta
     4801 taattttatc tattattaat gaacctagtt taaacatcca aaagatatct aatacaatta
     4861 tgaatggtta tatcgctaat actggtgatc aaagtttaga taacctttta tcacgtggtg
     4921 gtataatgag catgttagga tcagcttgtt tgataatact agctttagca ttaggtggac
     4981 ttttaattaa gtttgaaatt gtatcaactt taatcaacaa aataaaagat tttgtcaata
     5041 atgcaccaaa actaattggc ttaactacat taagttcaat aatgattaac atattagtcg
     5101 gtgagcaata tttatctatt attcttccag gaaaaacttt taaagattcg tttgactcaa
     5161 taggattgtc caaaaaatat ctaacaagaa ctttggcaga tgctggaact gcagtaaatg
     5221 ctattattcc atggggagta agtggaactt tcattatggg cgctttaaaa gtcagtactt
     5281 tagcatattt tccatatgct ttctttccat tactttgtcc aataataact ataatattag
     5341 gtttgacatt aaaaactaaa aagtataaag tttaagctaa cttgactatt tttagtttta
     5401 gagtaatact ataattaata ataatttatt gcaatgaaag aaatagtaga gctattatac
     5461 tgcttttaga gagttaatgg atggtgaaaa ttaacacata ttttagcttg aattacattt
     5521 tggagcattt atcttttata aagattcgtt taaccacgtt ataggttgtt gaggtatata
     5581 gatattttct ttctatatat gaagttgggt ggtaccacga aaaatcgtcc ctaagtcttt
     5641 aaaagactta gggacttttt tataaatttt ttaaattgga gatgtttatc atgaatatta
     5701 ttgatgaatt acaatggaga gatgcaatca atcaacaaac aaacgaagaa ggtttacgtg
     5761 aacttgttga aaataatagt atatctttat attgtggggt tgatcctact ggaggtagta
     5821 tgcatattgg ccatttaatt ccttttatga tgatgaaaag atttcaacta gcagggcaca
     5881 aaccttttat tttaataggt ggcgctactg gtacaattgg tgatcctagt ggtaggactt
     5941 ccgaaagaat gttacaaact cttgaaactg tacaagaaaa tgttgaaggt ctatcaagtc
     6001 aaatgaaaaa attattcggt aaagatgcca atgttactat tgtaaataat tatgattggt
     6061 tatctagttt gactttatta gatttcttaa gaagctacgg aaaagatttt aatattaata
     6121 ctatgctagc caaagatata gtggcaagca gattagataa aggaatttca tttactgaat
     6181 ttgcttatca aattttacaa tctattgatt ttttacactt atttaaaaac cataatgtgc
     6241 aattgcaaat tggtggtgct gatcaatggg ggaatataac ttctggttta gatttaatta
     6301 gaaaaaaaga aggaaacgat gcaaaagtat ttggtttaac tattccatta atgttaaaag
     6361 ctgatggcac taagttcggt aagacagcag gtggagctat ttggcttgat cctaagcgta
     6421 catctcctta cgaattttac caattttggt taaaccaaga cgatagagat gttataaaat
     6481 acttgaaatt ttttacattc ttagataaag aagaaattga ttttctagaa gaaaaagtaa
     6541 aaaatgaacc agaaaaaaga gaagctcaaa aaagattagc agaagaagta actaagtttg
     6601 tacatgatga agcagcttta caagaagctc aaaaaatcac ccaagcttta ttttctggca
     6661 atgtaaaaga cttaacagta aaagaaatcg aacaaggttt acaaaacatg ccttcattca
     6721 atactactaa caaaactaaa aatatagtag attggttagt agaaataaat tgtgaaccat
     6781 ctaaaagaca agcacgcgaa gatgtaataa atggtgctat taatattaac ggagaaaagg
     6841 taactgatat taattttctt gttaatccta atagtgcctt tgaaggtaag tatatgataa
     6901 ttagaaaagg gaaaagaaac tacttcttag taaaagtttt ataatttaat ccttaaacac
     6961 ttcagcatta atcaatgtat tgaaaaacaa gagttgtact ttggtttaac ataatcgatg
     7021 attatcagaa gttctagtat aaaaaagcac tacaagttca tgagcttgta gtgcttttta
     7081 ttgtgttaat taccaaacaa ccgactccag aaaccttttt taggtggttt ttcttcctta
     7141 tcttcgtatt cattatctat ttcttcgaat tgtttatcgt ctattgtgga tggttcttca
     7201 ttgaggtttt cattctcttt ctcttcaggt atatctttat gctgcacctc tgtaggctgt
     7261 tcccattctt gttgttgatc agtatcttta gactctccag taaatgttgc ttcttgtaca
     7321 ttaacatttt gtctctcatt aacagacgta tcaaaagaat aattaagtcg tctttcttcc
     7381 tctaattgat cttctaattt tttaatcttt ttattacttt ctaatgctaa tacttgttga
     7441 ttctctaaaa gtctattaag tgtatttatt tgctctttat ctctatttga ttgttcttta
     7501 tatatatcta tctggttata taattgtttt attgtctcat ctttcaccag gttatcatta
     7561 ttaggttctt cttttttttc gctttcaaaa tcatcattct tattttgatt ttttcttatt
     7621 cggtttatta ctataatttc atcttcactg gttaagtaat ttacgttatc gattttttga
     7681 aatttcacat ttgctttttt agcattatta taaacagtca tttttgttac gtttaattca
     7741 tcagcaattt ctttcatact cttcatataa cgccctccat atagttatat acataacgtt
     7801 tataccatta tacagccatt atatttgtta ttacaaggtt atataattct ttatacacat
     7861 aaccatatat aactatacgt ataaggtttc accccccaat tatataacac ttatacaccc
     7921 tttatacttg ctatataagc gtttatacgg ttttatacga tatacccata taaaataatt
     7981 tatacaaaga tttatctttc tttgaaagtg catacaccca aatgtatata aacaatttaa
     8041 caaaactttt aaaagtgtta atataaatat ataaaagaaa cctaactacg ggaatagtca
     8101 ggtttcttcg gtaataaaac aagtagtttg tttgtttata tagttgttat atttttatta
     8161 tatatactaa gaattattag tgcaagtcga atacatataa acttacttat agctttttta
     8221 ttacctcttt tagaaattta aatatgaaag aggttttttg tatgtccaac tttaatatta
     8281 aagaaatcca aaaagagaaa ttttatcaat tacctaaagt tttttttacg aatcctaaat
     8341 atactaaact atctaatgat gcaaaaataa cttggtcaat actaagagat cgtttagatt
     8401 tatctataag aaataattgg gtagatgaaa atggagatat attttttatt tataccaatg
     8461 aaaagcttaa gtctatttta aatattagta gtccaaataa gctatctaaa ataaaaaaag
     8521 aattaacaga agctgattta tttaatcaaa taagagtagg tttgaataaa cctaataagt
     8581 tatatattaa aaaaccagaa gtaacagaag ctgatgtata ttatatttca caacaagaaa
     8641 acgatataga acagcataat aacacggacg tatcattatc atacgtccag aaatatgata
     8701 atgatacgtc aagaaatatt aatatgatac atcatgacat atcaaaagaa tacactaatg
     8761 atactgattt aagtaatact gattatatag agactgagaa taatgatacg tatgatatga
     8821 atgatacata taacaatcaa acaaaccata atcattcgga tcatacaaat tatcaacaat
     8881 ccgaatttaa taatgatgca cttaaattcc aagtactcga agaattgcca caacaaatca
     8941 aagattactt aagtaatttt gaaatcagag aaattcgtat tattaaaagt gttttactca
     9001 aagggaaaaa atcttttaac aacacattaa atacatatta tcgtttagaa gatgtcgaat
     9061 ttgaacttgt cagtgtttta aaacgtttta aagccatgct gctacaaaag aatgaaaccg
     9121 ttgaagctat gcaaggatat ttaatgcaat cgattaaagc tgaacttgaa gaaatacaca
     9181 cacttaatat gcgtcgtcaa aacatgaaaa aacataatat ctttaaccaa taatttagat
     9241 aatcttatag caatcaaaga gacttcaaaa tactcggtta aatcatctga ttttttaact
     9301 gatgatgaaa aaaatcaaga aatcgtgaat gatttggaaa aaggttgata ccgaaaatgt
     9361 atgttgagtt atggtggatt gcttaaataa aaacataaaa ttttaaattt agacgatgcc
     9421 gaagatggca atttaattaa tacaagtgac gaagataaag caacagacga agaagaaaaa
     9481 gcacattcaa ttacggcaat ttggaatttt gaaaagcaaa attacttctt aaaaaatttg
     9541 taatgttgtc taaatataat aatattcttt gtaagaattt caaaaaaatg tataccaaat
     9601 gtagacattt ttgtgtagga ttgctcttat gctcttttga aaatacaaaa gttacattat
     9661 acacctattt tttaaggatt tagcttttta ttaagaagaa taaccgagat agaaaaacat
     9721 atttcgtatt ctaaaagatt tagaaaatga attttaaaat gatttatcgt ctctctgtcg
     9781 aacgaaaaaa gtttttagtc atttttttat acgtggaatg attaaatgtc ctagaaaggg
     9841 cttaaaatgc aaaataaaaa gactactcat tttttgagta gtctggagaa ttgtttttga
     9901 tatattaaat gaaaaggagt actacattaa tcatatcaca cgcatttatg ccgagaaaat
     9961 ttattgatgt tgggaagaac ccttaactaa acttggagac gaatgtcggc atagcgtgag
    10021 ctattaagcc gacgattcga caagttttgg gattgttaag ggttctgagg ctcaacgtca
    10081 ataaagcaat tggaataaaa attataatat ttaaactttt tatctataaa ctaacccacc
    10141 gtctgttaaa attgattgac cagttatata ttctgcatct tctgaagata aaaatgatac
    10201 taaattagca acgtctttag gctcttggta tctacctaat tttatagcac ttgaaaattc
    10261 tttaaaagcg tctccaggtt ttaagttttc gtcgtattta accatttctt catcgattct
    10321 atcccacatt ttagttttag ccactcctgg acagtaagca tttacgttaa ttttatattt
    10381 agctaattct ttagctgcaa cttgagtgta tgaacgaaca gcgtgtttag tagctgaata
    10441 tgtacctaac atttcgtaag attcatgacc tgctatacta caagcattta ttattttacc
    10501 ttttgtattt tgttttataa attgttttgc agcagcttga gtgccgtaaa cagttccaaa
    10561 tacgttgatg ttaaataatt tgtttaattg attttcgttt atttctaaga aaggtgttac
    10621 agcatctaca cctgcattgt taacaaaaac atctagttga ttaaattctt ttacagcaaa
    10681 attaactagt tcttcttgtt ctttttgttt tgaaacatca cttttgaaag atattacatt
    10741 atatcctttt tctttgaatt ctgtttctgt ttctagtaat aactcgttat taatgtcttg
    10801 aacaacgata ttaaaaccat catttgctaa tctttcggct attgctttac ctaaaccacc
    10861 tgctgaacct gttattattg ctactttatt ttctgatttc atatatttac agcccctttt
    10921 ctttatgaaa tgtctttaat aaaaattgta ttcctataaa aaaactaaag caatatttat
    10981 gtcttttgag gttctgttgc aaagttgaat ctatagtata attttaactt tgcaacagaa
    11041 ccgttttatt tattgtaatc tttttccatc tataataatg tttgcacttt caggcgtaac
    11101 ctcaaaacta agccctttac gtaccttaat attatagttc ccatcctttt tataatattt
    11161 agcattttct aattttaatt ctactttttt agaaagttca cgtagctcct ctattaagtc
    11221 atcttttaca atatttagtt ttgaagaagc atattcatca ctgtagaatt tactagaatc
    11281 atataattct tcataatgtt gaagtaactc aagaacttct tttctaggtg ttttcttgct
    11341 tattttaagt tcaaaaatac tatctttatt tatatatcta tgtgcttctt ctttaattaa
    11401 atcttcatta ttttcatatt cttctctact aatatttaag ttctgcatat gtctttgaat
    11461 tctttcttca tcttctaatt cttgttgttc aatcatttgt cgaagtctat cttcatgttc
    11521 taattttcgt agctcttctt ctcttatttc ttctaacaat tcctgatata cttgaacatc
    11581 ctttaatagt tcatcaacat ctgaaagtaa tttttcagtg tactcttctg ataagaatgc
    11641 tctttctcta cataattgca tccataatac tctaggttca taaccgtcta tataccattc
    11701 ttcagccgtt ggtataagaa actcaacaag tcctttaaac cctctatctc catttgtctc
    11761 tttggtaatt aaagcatgta atatcaaatg ctctattaag tcacaatata ctagattctc
    11821 tttatgatga tattcataag ggtatttata atgagctata tattctttgt tagatatatt
    11881 ttcatattca ttttccaata tgtgatgaca atataaacct tcttttgttt ttgtatattt
    11941 accgtatgca attctcttta tttccccatt taaaaatttg ttataagatt tttctttata
    12001 gtagttatct acaacttcac catgtttttc aattaaagat tgaacagcat cactgtatga
    12061 taaacttaac agctctttat aataattata ttttttttcg tataaatcat aagattccat
    12121 aaaactattt tctcccaaca ttgtataata ctgttttcaa ttgattatta atttaatttt
    12181 ctaaatttgc aacagaacta gaataattaa cacgaaaaat gagtagcata attgctactc
    12241 ataaatattt ttatcaaaaa cttccaactt ggttacttta ggaatttcag gaaacaaacc
    12301 aaaattaagg ttctgttgca aagttgaatt tatagtataa ttttaacaaa aaggagtctt
    12361 ctgtatgaac tatttcagat ataaacaatt taacaaggat gttatcactg tagccgttgg
    12421 ctactatcta agatatgcat tgagttatcg tgatatatct gaaatattaa gggaacgtgg
    12481 tgtaaacgtt catcattcaa cggtctaccg ttgggttcaa gaatatgccc caattttgta
    12541 tcaaatttgg aagaaaaagc ataaaaaagc ttattacaaa tggcgtattg atgagacgta
    12601 catcaaaata aaaggaaaat ggagctattt atatcgtgcc attgatgcag agggacatac
    12661 attagatatt tggttgcgta agcaacgaga taatcattca gcatatgcgt ttatcaaacg
    12721 tctcattaaa caatttggta aacctcaaaa ggtaattaca gatcaggcac cttcaacgaa
    12781 ggtagcaatg gctaaagtaa ttaaagcttt taaacttaaa cctgactgtc attgtacatc
    12841 gaaatatctg aataacctca ttgagcaaga tcaccgtcat attaaagtaa gaaagacaag
    12901 gtatcaaagt atcaatacag caaagaatac tttaaaaggt attgaatgta tttacgctct
    12961 atataaaaag aaccgcaggt ctcttcagat ctacggattt tcgccatgcc acgaaattag
    13021 catcatgcta gcaagttaag cgaacactga catgataaat tagtggttag ctatattttt
    13081 ttactttgca acagaaccat aaactataaa tgactgtact actacttgtg caaaagataa
    13141 tgctatacga atgcttttct tagttttctc actcattttc ttcaactcct tttgttgctt
    13201 tattccaatt gctttattga cgttgagcct cggaaccctt aacaatccca aaacttgtcg
    13261 aatggtcggc ttaatagctc acgctatgcc gacattcgtc tccaagttta gttaagggtt
    13321 cttctcaaca tcaataaatt ttctcggcat aaatgcgtgt cttattattt atttttattc
    13381 actttaaata aaaaacgtcc caagtatgct acataataat acttaagacg ttttaatttt
    13441 tatttagttt ttatctcctt taactttatc aatcaagtca ttagctttat ctttaacatc
    13501 atctactact tctttggctt taccagaagc tttatctcct ttaccttctg cttttaaatc
    13561 cttattatca gtagcatctc caatagtctc tttgatattt ccttttgctt gttcgaattt
    13621 ttcttcgctc attttctatt cctcctaaat aatcaatgtc tacaatacaa ttctattatt
    13681 caaataccct ttttaaaagt gaaatcatat ccttttttat cccatgcatt aaaccttgta
    13741 ttatcccatg tatacaaaat gattggttct gttgcaaagt aaaaaaatat agctaaccac
    13801 taatttatca tgtcagtgtt cgcttaactt gctagcatga tgctaatttc gtggcatggc
    13861 gaaaatccgt agatctgaag agacctgcgg ttctttttat atagagcgta aatacattca
    13921 atacctttta aagtattctt tgctgtattg atactttgat accttgtctt tcttacttta
    13981 atatgacggt gatcttgctc aatgaggtta ttcagatatt tcgatgtaca atgacagtca
    14041 ggtttaagtt taaaagcttt aattacttta gccattgcta ccttcgttga aggtgcctga
    14101 tctgtaatta ccttttgagg tttaccaaat tgtttaatga gacgtttgat aaacgcatat
    14161 gctgaatgat tatctcgttg cttacgcaac caaatatcta atgtatgtcc ctctgcatca
    14221 atggcacgat ataaatagct ccattttcct tttattttga tgtacgtctc atcaatacgc
    14281 catttgtaat aagctttttt atgctttttc ttccaaattt gatacaaaat tggggcatat
    14341 tcttgaaccc aacggtagac cgttgaatga tgaacgttta caccacgttc ccttaatatt
    14401 tcagatatat cacgataact caatgcatat cttagatagt agccaacggc tacagtgata
    14461 acatccttgt taaattgttt atatctgaaa tagttcatac agaagactcc tttttgttaa
    14521 aattatacta taaattcaac tttgcaacag aacctagttt attatgctta caagcaatat
    14581 aaattatcta aagaaaatta atttttgatt atgtaataag ttttggtact aaaaaagact
    14641 tgatctgatt agaccaagcc ttttgatagt gttatattaa taaacaaata aaaagaagtc
    14701 gctcacccac cgaccaaagt ttgtgaacga caatccaaaa agaaaacatg agttgttttt
    14761 tatgaatttg tatatttaaa tactaaacga tatttaaata tacatcaaga taaatattcg
    14821 ggtgggcgac ttcttaaatt aaattaagga gtcgattttt tatgagtaga aaagagcaag
    14881 aaattcattc aaagcaaagc acattacaag aagttacaaa ttacacctca accggatact
    14941 ctaatagccg gttaggagtg cattctgtgc acccacaaaa tcctaaatta agttttgacg
    15001 ctatgacaat agttggaaat ctcagtcgtg acaacgctca aaagctatcg tcatttatga
    15061 gtatcgaacc acaaattcga ctttgggata tactacaaac gaaatttaaa gctaaagcac
    15121 tgcaggaaaa agtttatatc gaatacgaca aagtaaaagc agatacatgg gatagacgta
    15181 atatgcgtgt tgaatttaat ccgaataaac ttacgcatga agaaatgctt tggttaaaac
    15241 aaaacattat caactacatg gaagatgacg gttttacaag aatagattta gcttttgatt
    15301 ttgaagatga tttaagtaat tattatgcaa tgactgataa agcagttaag aaaactgtat
    15361 tttatggtcg tgacgggaaa ccagaaacaa aatattttgg cgttcgtgat agtgatagat
    15421 ttattagaat ttataacaaa aaacaagaac gtaaagataa cgcagatgtc gaagttatgt
    15481 ctgatcactt atggcgtgta gaaattgaac ttaaaagaga tatggtggat tactggaatg
    15541 attgttttaa tgatttacat atcttgaaac cagattggac ttcgccagaa aaattaaatg
    15601 aacaagcaat ggtttacatg ttaattcatg aagaagacaa atggggagaa ttgaataaaa
    15661 gaactaaata taaatataaa aatttaatta aagaaatatc tccagttgat ttaacggaat
    15721 taatgaaatc gactttaaga gaaaatgaaa aacaattaca aaagcaaata gaattttggc
    15781 agacaaaagg taagaagcta ttttaaaaat ggctaccatt tgactccctt ttagctccca
    15841 aatggctcca taaaaaggga gctatttggg agctattttt gattttatgt agccatttgg
    15901 gagtcatttt tgattttggg tagctattcg gtagcttttg tgtagtcgtt cgggagtcat
    15961 ataacaattt ttatcgcata aataggaatc ccatttgaca ctgtcaaatc aatattttgc
    16021 acagaaacgg ctaccgaatg gctacatacg gagacatttc tgtgtaggat tcctcttatg
    16081 ctcttttaaa atattttaaa atataaaagt tacattatac acctattttt ttcaggtttt
    16141 agctttttat tgagaaggat aattaaaata aaaaaacata tttttttctg aaagtgttga
    16201 gaaataaatt ttaaaatgat ttatagcctc tctgttgaac aaaaaaagtt tttagtcatt
    16261 tttatacgtg gaatgattaa atgtcctaga aagggcttaa aatgcaaaat aaaaagacta
    16321 ctcatttttt gagtagtcta tctgtaggat agtttttgat attctaaatg aaaaggagta
    16381 atacataaat catttggttc tgttgcaaag ttgaatttat agtataattt taacaaaaag
    16441 gagtcttctg tatgaactat ttcagatata aacaatttaa caaggatgtt atcactgtag
    16501 ccgttggcta ctatctaaga tatgcattga gttatcgtga tatatctgaa atattaaggg
    16561 aacgtggtgt aaacgttcat cattcaacgg tctaccgttg ggttcaagaa tatgccccaa
    16621 ttttgtatca aatttggaag aaaaagcata aaaaagctta ttacaaatgg cgtattgatg
    16681 agacgtacat caaaataaaa ggaaaatgga gctatttata tcgtgccatt gatgcagagg
    16741 gacatacatt agatatttgg ttgcgtaagc aacgagataa tcattcagca tatgcgttta
    16801 tcaaacgtct cattaaacaa tttggtaaac ctcaaaaggt aattacagat caggcacctt
    16861 caacgaaggt agcaatggct aaagtaatta aagcttttaa acttaaacct gactgtcatt
    16921 gtacatcgaa atatctgaat aacctcattg agcaagatca ccgtcatatt aaagtaagaa
    16981 agacaaggta tcaaagtatc aatacagcaa agaatacttt aaaaggtatt gaatgtattt
    17041 acgctctata taaaaagaac cgcaggtctc ttcagatcta cggattttcg ccatgccacg
    17101 aaattagcat catgctagca agttaagcga acactgacat gataaattag tggttagcta
    17161 tattttttta ctttgcaaca gaaccgtcgc gccaatatac taatcgtgaa aagacaccta
    17221 aatggttaga cgacaagata tataaacaat ctcaagagtc acatggcgaa gatgcaaaat
    17281 taaaacaaga tcgagaggca tttcaacgtc aattagaaga aaaatgggag gaataataat
    17341 ttaaatgagc tacatgtata ttttaatctt atttccatta ataatgggat ttatcgtatc
    17401 aataaaaaag aaaaaacatg actaaggaga tataagaagg tatgagtaat aaatataata
    17461 tacatccagc actatatata ggaggatttg cggtattttt tagttttata tttggatttc
    17521 ctgtaggaac attaatgggg ctagctatag gaataggagt tagtaaaaaa aataaaaatt
    17581 tgtaaaagag tttacagatg aaggagttac aagatatact aaaaataaca aacagacaga
    17641 cacatcattg gatgtgaaaa ccccagcatg ccgaccaaag catatgctgg ggtttctttt
    17701 ttatcgttgt tcttgattta ataaataaag aacacgtcca acaataattg gacatacgat
    17761 atatttcaca acaaacagaa cgacaatcac tagatgtggc acctcctttc tgcacgggaa
    17821 gtgctttttt agtataacaa aatctgattt taataggttt tttaattttg aataaagata
    17881 caaaagttca cttaatgaaa aaatatgaaa acgcgtcgtt aaagggatgt ataaaagttg
    17941 tataaagagg aatgatgaca aatagggaca aacgccgtca tttcagcgtt tgtccctgat
    18001 atgttagtta acataattat gtattatggg tagtgccttt gtataaatac tcaaaaacac
    18061 aaacattgtt aaattaatct ttgtgtcctt taatataagt aacataatag ttaattattg
    18121 cgatgagaaa aaccatagat aactaaatat ataagcataa taactatgaa atgaatagct
    18181 cctaaaaata atgcgaaaat atctgtagta agaggtttaa aataatctga tgaatcgtaa
    18241 atattcataa accaatgaac acattcccaa gaaagaaatg ttccaataca tctacttatt
    18301 ataatactta tattattttt taagccgaat ttaaaaatag atctacttat taatatagca
    18361 actattataa atgggatgta gcctattaat aaacctgttt gataatcagt aaataatccg
    18421 ataaattcta ttggaactaa agataaaatt aatataatga tttttaacca tttcatttta
    18481 aaagttctct cctcaatata attattcttt taatatcatt ttatttaatg taatttttaa
    18541 ttgtaaataa aattaaaaat ttaaacaaag tcaatacaga agagattcaa gcagaactac
    18601 gacaagagat tcgtcaggtt caagatgaaa acaaagaaat gttacgtgaa gtgagagcat
    18661 cacatgagca ttatcagaaa agacaaaaac aattatttac agggattgga tcaatattat
    18721 gctatttgct ttaattatga ccataggcag tgactttatg agtttcttgc atgtagatat
    18781 attacaaaaa gccatagcaa gcaaaatcaa agcgtctgaa ggttttatga catttgtttg
    18841 gtatattgtg catatggttt gccttatata ttcgctatag gactatttat tggcttatat
    18901 gagtggatta gagtacgatt ccataattaa aaatgaatgt gataaagtct gtatgaaaaa
    18961 aggagcttta aatattttgg aattcttgta tgtttgtaaa aaaatcatgg atattttggt
    19021 tagtatagta acagttttgg aagaagacgt agcaagaatg ttagttaaaa tcagcgaaag
    19081 aattaaaaaa ggtggtttta ttttaaaaat tgttttattt ttcacatatt attttgtttc
    19141 ttgttttatt ttgtcttcct tatgtgattt attactttca acaaaatttg atgtatatat
    19201 aaatgtaatt gcagcattga tttttgcagt atgtatgaca cctcttactt ttatattaaa
    19261 ggacgataaa aacaagaagt agagcacgca tttatgccga gaaaatttat tgacatctag
    19321 agatgagtat aaaaggaaag gttaatttta tgttattaaa aaataagatt tattcaggca
    19381 ttattattgt tatttttata gtttgtttga ttataggatt gaatgaaaat atcattggaa
    19441 atcctttagg agaaaaaata tttcatttat taagtttttt attttttgta ttattaataa
    19501 ttggtacaac aaaaaaaaga aggcattaat gccttctttt ttatgctcca ttatgggtag
    19561 ttaaaatgta tagattatat atttaacacc ttaatttttt agcttctttt atacgaccga
    19621 actgcttttg atggaatata ttgattgaga ctatatggct caataataaa ttgagatgta
    19681 acaaccggaa gaactgataa tcgtccggca ccataataat acgattgcca aacaagtttc
    19741 gaacagtatg taacgctttt agaatatgga ttcgtcgtta tactgtaagg tacaccgtta
    19801 aaatgagatt tcgcatagct tccagcttta cctctatatt tttttggtgc tcgataaacc
    19861 ttgatataac gatgtttggg acttcctttt ctttttttca aagtactctt tttccaatta
    19921 ctaaaacttt ttaccctcac aggttttcca tatccaggcg cttctttaac ttttcctttt
    19981 ccaatatata ttgcagcatg acctgtaaac ccttttgaac ttacgttatt tgtgatgaaa
    20041 aaatcacctt ttttcaaatg aaatttcttt tttcttgaac gattttctcg atctattcga
    20101 tcttgttttt gttgtttctg ccattgtact tcagctgttt tctcaaattc tgcttcatct
    20161 ttacgctctt gagctttcat ttgttgccat tgttgttcag taattgattt agacacaata
    20221 ccttcatttt gaagttcctt taacgactca gagttagttg agctatcacc ttgtgcattt
    20281 acatttcctg tagttaaaac tgtgcaacat aataagctca tcattaactt tttcattgat
    20341 tctctcctct gatttgactt tattacattt aaaaacatat cataaatatg tattattgta
    20401 tttaatttta caaaatatta attaaataaa taaatttact taaggagacc aatatgaaaa
    20461 gaaaatataa aattataggt atcatcttta tcgttcttct tatcgtttta acattaattt
    20521 ttagtatagt gcaccattat gctaatgttc aaaaacatga agaagctaaa ctaagacaaa
    20581 aagttcacca tattttcaaa caaaaaggtt gggaagataa agttaaagaa gaacaaaata
    20641 tatttacgtt caatactgga gataatgatt tacaagtcac ttttaaagat gagccttata
    20701 atacgtatac atactctatt gatgaaaaca ataaagtata tggaaatgct gttttgaaag
    20761 atgaatatga taaagatttt gatagtaaaa aaaagtacaa agaatattta agaaaaatgc
    20821 attttgaaga aaaatatgat ctgaaataaa aaagcaagcg actatcaatt atcgtagtcg
    20881 cttgcttttt tattgttctt tcaatcgttt aatcgcattt ttcagttgac gatcatcgcg
    20941 atatgtattg aagttaaaaa atgctgtact atcaaaatgt tgtaataaat gatgaaaaac
    21001 gtcattttct tgtctcagtt ggtcgatttc atcttccagc tgatgaatat gttgctgaag
    21061 ttcttgattg ttcgatttga gtgcctcgtt gtctttttta aacaattcac tgacttcact
    21121 ggattcttta atttgttcga tgactgtcgg tttaatacga ttaccaatgg ctgtatgacg
    21181 tatgtattcc gtcacattca tctctcgaat atccgcaagt tcacaaatct tttcgtattg
    21241 cgattgactt acacgaattg ttaaaatttt ttcttttgaa ttttgttttt ttggcattga
    21301 accacctcat gattaatata tgataagcat acatatgtgt gcttatcttt atattaatat
    21361 aacatacata tgtatgctaa taaatatgta tgattcgagg tggtatgagc taacatttgg
    21421 catacatatt ttcaaacata gttgtttgat aaggtgtatg tcatttgtta gctatagaac
    21481 ggcattcaaa aatatatttt tgaatgccgt aatggcctcg ccagagcgaa gataactctt
    21541 acatttgaat gtaagagtat atcgagctat actctcattg cggaatcagc ctcacatgtt
    21601 tgaggcgtag cggtgagagt atccatcatt ttacataagc gaagcattgt cgaaggtaga
    21661 caatcacagc gcttgtaaaa tgatatttgc gaaggttctc gaaagtagag aaccacagac
    21721 aaatcaaaaa gcttcgggga gggcgctcaa tttgaaatta gcttggaata cgcaaaaaaa
    21781 taaaatgagc gatgttaaag gcaaagagat ggaacaagaa cgtaaaggga gaatcaaaaa
    21841 cgatgagatt gatttgaaac gaacaaactt aaactttgat ttagttgaag atgaacgtca
    21901 tttgtaccat cgtgtgaaag atagaattga gtactataaa aaacaaggct cacgtgtaca
    21961 gaaaaatagt gtggtgatgt attccaatat cattacgtta tcgaaagaag aggccgaccg
    22021 tatgggagag acgcgtacaa aacactactt taagacatgt aaagattact tcagtgaacg
    22081 ttttggtgaa gccaatgtcg tttcagcgaa agtgcatatg gatgaatcag cgcctcatat
    22141 gcaccttcac tttatacctg ttaatcatca agggcggtta tcagcacgta cagctatgaa
    22201 tcgacaagcc attaatcaca tccatgatga attaacaaca catctgtgcc agcaaggttt
    22261 tgatgttgaa cgtgggagta ccgatgataa taaaacgtat attcaagata ttcatgaata
    22321 taaaaagaaa gcgaaagttt taagtgaatt agaccaacaa attgaaacga aaaaacaatt
    22381 gttgagggat atcaacgatt tacacgatga aaaagaaaat ttaactcggg atattcaaaa
    22441 cttaaaacgg aaaaatcatt ttttacaaga ggattctcaa caggctcaag aagatatcga
    22501 cctatacaag caactgagaa cgatttctag ggacgatttt aaaaaagagg aggaaaagta
    22561 ccaaaaagaa atcaaagcgt atgaggcgtc tctgagtggc cttagaatga attaccgaga
    22621 tttggacaag cgcaatcaac atttaacaac acaaaataat caactcgaac accatttaga
    22681 catgttaaat gcacgtcatc aagcgatgaa cgacatggta agaaatgata cacgtatttt
    22741 gtttgcggga cttagatgtg cattgaaaga tatgaacatt gaattaagcg cagaaattaa
    22801 atatcaacgt atgccagaag tcggtattga tcccgatacg gtggatcagg gggctttaac
    22861 acatgcatat caaggtggtg tgtcagggat agaccatcat ataagaaagg catcatcacc
    22921 tattaaaaaa gaggcagaga atgacttaga attagaataa atcaataaaa taagcactca
    22981 aacaagtatg atactcgcct gagtgcttat ctcatgaaaa gaggagataa aaatttaata
    23041 agtatgatta accgattaag aacaatcatt accttactta cagcgcttat taaatagttc
    23101 tgtaaggagg aacaatacct ttgcatttct atgttattat aagaattccg aggtagcaat
    23161 gatattgact taatatgagc aaattgatat tggaagcaaa agaaacccac tcgttcgttt
    23221 gagtgggttt tgaaaaatga tacgtattaa cttgataaaa ttaatcattt tatagtttaa
    23281 ggaaaaggaa tgcataatta tagtaacaca aattaatgtt tgttacgcta atagtgctgc
    23341 tcaatatata aagtagtaaa ccataactat tcttcgcatc tctttttaaa aagttaattt
    23401 tttgctttgt acaaggaaaa gcactcaaaa ttgagtgctt ttttcatatt aaaattaaac
    23461 tttaaaaatt aagacagcga cactgacatg tgtcgctgtc ttaagatata ttatatgagt
    23521 tcaaaagata tatagctatt gtagcataat agtgttttta ttaaaaaaca agacgaaata
    23581 gtttgaatta ctgaataact tatgtcttaa atcttttaat ttatttaaga tacgttgtta
    23641 ttaagaaaat aaaaaaagat ataaatcaat tatttagttg atttatatct tcatatgtat
    23701 tgatttaaaa tatttactac attaaaccaa acgctttagc aacgtctgat attacaccaa
    23761 taccattagc tgcaatatca acaattgatt tagctaattc ggcactatct ccagattgtg
    23821 atgctgaaat agtattaaca atagcttcac ctaattttga aatatgttcc atgaaaaaca
    23881 aacctcctta catatcaaat cattactcaa ataaaataac atatattacg ataattctct
    23941 tctactttta aataattgta attaaattta cgttttctta aaaataaata aagggattgc
    24001 aatgttgtta ctattaaaat taataaaaaa actgtgaata taataatagc tattttacat
    24061 ggaatttttt aatatctttt tataaacctt tttagaagtc gtttgagctt tagagccaca
    24121 gcttatttga gatgtttaag gagtagtttt gccacataaa aggagtagtt tttattataa
    24181 accttctttt gttaattgac attgttatca aagtgtttta acgtgaaaat atcaattcaa
    24241 taaggagtat cataaaaaaa catgctcctt attgaaataa ttatgttgag gtatctatat
    24301 aatgacggga gaaacagtag tatacaaaaa cgatttgaat ttagttcctt taagaaaatt
    24361 caccagtact gaaattaatt tattttttgc catgtgtaat aaacttaagg aaaaagaaac
    24421 taacacactt catttatctt ttgatgaatt gaaagaattg agtaactata gtccgaaaac
    24481 acgtaatatt aatagattcg ttaaagactt ggatgatgta tataagaaaa tgttggaact
    24541 aacaattaga tacgaagatg atgaggttat agaaagattt attttattta atcattatag
    24601 aattcataaa aaagataaat acttagaaat ttcaacttct cctaatttaa agcatatact
    24661 taattcaatt actagcaact ttactaaatt tgaattaaaa gaaatgacaa atttgaaatc
    24721 tacatattca aaaaacatgt ttagaatact taaacaatat aaacacactg gttatatgaa
    24781 aattaaaatt gatgatttta gagaacgcct agatatccct aaatcttata gaatgacaga
    24841 tattaataaa aatgttttga agcctattgt tacagagtta aacgctattt ttaacaatct
    24901 tcacattaat aaaatcaagg ctaaaaaagg acgtaaaatt gaatggttag agtttatctt
    24961 tgacgctgag aagtgtatac atagtaaacg aaaacctgaa agacaagata aaattatgtc
    25021 taagcgctat agtagtcgag aaaaaacacc taaatggtta gagaaaaaag aaggttctgt
    25081 tgcaaagttg aatttatagt ataattttaa caaaaaggag tcttctgtat gaactatttc
    25141 agatataaac aatttaacaa ggatgttatc actgtagccg ttggctacta tctaagatat
    25201 gcattgagtt atcgtgatat atctgaaata ttaagggaac gtggtgtaaa cgttcatcat
    25261 tcaacggtct accgttgggt tcaagaatat gccccaattt tgtatcaaat ttggaagaaa
    25321 aagcataaaa aagcttatta caaatggcgt attgatgaga cgtacatcaa aataaaagga
    25381 aaatggagct atttatatcg tgccattgat gcagagggac atacattaga tatttggttg
    25441 cgtaagcaac gagataatca ttcagcatat gcgtttatca aacgtctcat taaacaattt
    25501 ggtaaacctc aaaaggtaat tacagatcag gcaccttcaa cgaaggtagc aatggctaaa
    25561 gtaattaaag cttttaaact taaacctgac tgtcattgta catcgaaata tctgaataac
    25621 ctcattgagc aagatcaccg tcatattaaa gtaagaaaga caaggtatca aagtatcaat
    25681 acagcaaaga atactttaaa aggtattgaa tgtatttacg ctctatataa aaagaaccgc
    25741 aggtctcttc agatctacgg attttcgcca tgccacgaaa ttagcatcat gctagcaagt
    25801 taagcgaaca ctgacatgat aaattagtgg ttagctatat ttttttactt tgcaacagaa
    25861 ccgaaaatag aaatatatac aaaaaacatt ctaaaagaga cgcatgctaa taataaaaaa
    25921 agaaacgaac taaaaacatt attaaattca aaattagttt ttggtgatac attgtatatt
    25981 acagatttgt gtattattgc agattctaca aaacacttag tagatatact agatttactt
    26041 tctgccaaag gaatttcact atacataatt aatttaaata aaaatctcat tgcagatacc
    26101 aatgaaaatt ttataaaaac attacatgag attactgatt ttcaaagcga cattgtaaaa
    26161 tttagaacac gtatggggtt agagaattat acaagagaag gtaaacgtct tggtagacct
    26221 aaacgtgatg ataaaaattt aagagatgct atagaaatgt atatgagtaa gaaatataca
    26281 ttagatgaga taaaagaaaa aacaaatata agtagagcca cattatacag acatttagat
    26341 aaataataca ctccccttag ttgttaaata aggggaatgt atatagagta tgagtatttt
    26401 aattattatt tatattaata aaatagaata cctaaaataa taccaatcaa aacaatagct
    26461 caagaaggaa gtttaaaata cattaatatt ctttcccatt taaataatca gcagttttaa
    26521 tcacttcatc ataattacga cataaacgat tgccttaata aaaatagtat gagactcaga
    26581 ccaatagtta cttgtgtttc tttgttgttc gaaagaaaat ataagtgtag atatataata
    26641 taaaaagaga gtgtacagaa aatggttatt ttctgtacac tctcttttta tatctagata
    26701 tatagctagt atacatattt tagtgttcaa taacccaaca gaaaatctat gttcataaat
    26761 agggttagaa ttaagttatg gtacaatgaa aatgtacata ggaggtttgt attttgaaaa
    26821 taggttatgc aagagtctca actggtttgc aaaatttgaa tttgcaggaa gatcgattaa
    26881 atcaatatgg ttgtgaaaag atatttagcg atcatataag tggatcaaaa agtaaacgtc
    26941 ctggtttaga taaagctatt gaatttgcga ggtcaggaga tacgattgtt gtttggagac
    27001 tagatagatt aggacgtaac atggaagatt taatcacatt agttaatgaa cttaataatc
    27061 gaggcgtgag ttttcatagt ttagaagaaa atataactat ggataaatca agttctacag
    27121 gacaattgtt atttcattta ttcgcagcat ttgcagagtt tgaacgtaat ttaattttag
    27181 aacgttcttc agcggggcga attgcagctc gtgctagagg acgctatgga ggtcgacccg
    27241 aaaaattaaa taaacaagat ttaaaattac tcaaaacact ttatgataat ggaacaccaa
    27301 ttaaaactat tgcagaacaa tggaaagttt cacgtaccac aatctatcgt tatctcaata
    27361 agttaaataa ccaagaaaat aaagataaat aatattacta aattttaaga aagataaaaa
    27421 ttagacagga tacaccctaa tcatacagat gtagttgttg aatttatagc atcttaaacg
    27481 tatgattagg gtgtatatta attgtggggt gacgatgaat gattataggt tatgcaagag
    27541 tatcttcgat agatcaaaat ttagaaagac agctagataa tttgaaaaca tttggcgtag
    27601 agaaaatatt tacagaaaaa caatcgggaa aatcagtaga aaatagacct gtatttcaag
    27661 aggcacttaa ctttgtgaga atgggcgata gatttgtagt agaatcaatt gatcgtttag
    27721 gacgtaatta tgatgaagtt attaacacag ttaattattt aaaagataaa gaagttcaat
    27781 tgatgattac gagtttacct atgatgaacg aagttatcgg cattccctta ttagataaat
    27841 ttatgaaaga cttaattatt caaatattag cgatggtttc agaacaagaa agaaatgaaa
    27901 gtaaacgtcg acaagaacaa ggaattaaag tggctaagga aaaaggtgta tataagggac
    27961 gcccattact ttattcagcg aatgcaaagg atcctcaaaa acgtattatt tatcatcgag
    28021 ttgtggaaat gttagaagaa ggcaaagcta ttagtaagat tgcaagagaa gttaatatca
    28081 caagacaaac aatctacaga attaagcatg ataaagggga aatatgattc ttaatgagaa
    28141 tgagaacttt tcacaacgtt tcagcataca caacttaaga gttaattgag actttacatt
    28201 atatatatag tatatatt
//
