LOCUS       NZ_CP065558            12001 bp    DNA     circular CON 14-FEB-2024
DEFINITION  Klebsiella pneumoniae strain FK 6768 plasmid unnamed4, complete
            sequence.
ACCESSION   NZ_CP065558
VERSION     NZ_CP065558.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN17005574
            Assembly: GCF_015999625.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 12001)
  AUTHORS   Liao,W., Wang,L., Zheng,X., Zhang,Y., Chen,T., Zhou,C., Xu,Y.,
            Chen,L. and Zhou,T.
  TITLE     tetA Variant mediating Tigecycline Resistance Evolution in
            KPC-2-producing Klebsiella pneumoniae during tigecycline treatment
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 12001)
  AUTHORS   Liao,W., Chen,T. and Zhou,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-DEC-2020) Department of Clinical Laboratory, First
            affiliated hospital of Wenzhou medical university, Nanbaixiang
            Street, Wenzhou City, Zhejiang Province 325000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. SEP-2020
            Assembly Name                     :: FK 6768
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/14/2024 02:40:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,932
            CDSs (total)                      :: 5,810
            Genes (coding)                    :: 5,444
            CDSs (with protein)               :: 5,444
            Genes (RNA)                       :: 122
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 12
            Pseudo Genes (total)              :: 366
            CDSs (without protein)            :: 366
            Pseudo Genes (ambiguous residues) :: 0 of 366
            Pseudo Genes (frameshifted)       :: 262 of 366
            Pseudo Genes (incomplete)         :: 122 of 366
            Pseudo Genes (internal stop)      :: 26 of 366
            Pseudo Genes (multiple problems)  :: 44 of 366
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP065558.1.
            Bacteria and source DNA available from Department of Clinical
            Laboratory, the First Affiliated Hospital of Wenzhou Medical
            University.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..12001
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="FK 6768"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="unnamed4"
                     /geo_loc_name="China"
                     /lat_lon="28.01 N 120.65 E"
                     /collection_date="2019-05-23"
                     /collected_by="Department of Clinical Laboratory, the First
                     Affiliated Hospital of Wenzhou Medical University"
     gene            join(11736..12001,1..13)
                     /locus_tag="I7S93_RS29335"
                     /old_locus_tag="I7S93_29140"
     CDS             join(11736..12001,1..13)
                     /locus_tag="I7S93_RS29335"
                     /old_locus_tag="I7S93_29140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014542884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family ribbon-helix-helix protein"
                     /protein_id="WP_000093040.1"
                     /translation="MSSATSIRLDEELKDRLKTLADDRHRSAHALMLEAITEYIDREEK
                     RSQYLRDGQAAWQHYQETGLHLTAEEAEAWISTWGTENEQDAPPCHR"
                     /name="CopG family ribbon-helix-helix protein"
     gene            1..315
                     /locus_tag="I7S93_RS29340"
                     /old_locus_tag="I7S93_29145"
     CDS             1..315
                     /locus_tag="I7S93_RS29340"
                     /old_locus_tag="I7S93_29145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136729.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]; GO:0009432 - SOS response [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_071177730.1"
                     /translation="MPQVTISALAQRDLQRLQDFLKTKNRLAARKGGEVIVRAIQQLKT
                     LPDIGRPVPFLPLEYKELVIGFGDSGYVMLYRHDREMDQIVIVTVRHQKESGYPGADSL
                     "
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            480..908
                     /locus_tag="I7S93_RS29345"
                     /old_locus_tag="I7S93_29150"
     CDS             480..908
                     /locus_tag="I7S93_RS29345"
                     /old_locus_tag="I7S93_29150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001140599.1"
                     /translation="MAKTLLNLSQAAQAAGITRRTLYNHVKQGKVTVSRDGKNNPVVDV
                     SELIRVYGNVNIPEKQIPGISHRENTQKNFPQEQLLAMQKELADLRQAVTLMLEDKTSR
                     EEERRQHDDERRKLQAEVDRLTTELTQKKKRFWSGWFS"
                     /name="hypothetical protein"
     gene            934..1113
                     /locus_tag="I7S93_RS29350"
                     /old_locus_tag="I7S93_29155"
     CDS             934..1113
                     /locus_tag="I7S93_RS29350"
                     /old_locus_tag="I7S93_29155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165970.1"
                     /translation="MTKQEKTALNMAKFIKDQSLLLLEKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(1140..1670)
                     /locus_tag="I7S93_RS29355"
                     /old_locus_tag="I7S93_29160"
     CDS             complement(1140..1670)
                     /locus_tag="I7S93_RS29355"
                     /old_locus_tag="I7S93_29160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_071177729.1"
                     /translation="MALYMVFIEDVEDKDGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGENPQWERDKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIEVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(1677..2408)
                     /gene="mobC"
                     /locus_tag="I7S93_RS29360"
                     /old_locus_tag="I7S93_29165"
     CDS             complement(1677..2408)
                     /gene="mobC"
                     /locus_tag="I7S93_RS29360"
                     /old_locus_tag="I7S93_29165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_071177728.1"
                     /translation="MTLEQYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRAKYPVDGRQVSVWGLTPHGVAFSFDEDEPLTDVIPFQP
                     SRVSAAQLPHRLAVQSLRLSMEGRGATGWRYLHRMALKGMKVPDALAELDGRTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRRANGIDEIWYICPDRPTLVRVQRAILAVDEIVNPQTGEA
                     RKTVELDRERLFACFKFMTTE"
                     /name="mobC"
     gene            complement(2408..3277)
                     /locus_tag="I7S93_RS29365"
     CDS             complement(2408..3277)
                     /locus_tag="I7S93_RS29365"
                     /inference="COORDINATES: protein motif:HMM:NF024108.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_232254647.1"
                     /translation="MRSSSRRGANIQQVLAAAYALPEALKKDVKGLITKLENVADLSVL
                     QTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARDEFRRWPHASIM
                     LDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPADFVKTTVLDNTPIR
                     WFYRAASQESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQKEARPLFDVNTL
                     QHLPDGFAVMTGLGVARLAFSSPLRVERREISLKTFPVLAKTDPLAEYLPPADGGGPKA
                     DDDFAGLY"
                     /name="TraM recognition domain-containing protein"
     gene            complement(3343..4005)
                     /locus_tag="I7S93_RS29370"
     CDS             complement(3343..4005)
                     /locus_tag="I7S93_RS29370"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA transfer
                     family protein"
                     /protein_id="WP_232254648.1"
                     /translation="MFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLVAGVLL
                     ARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNALADFS
                     TEQARKQQAVFLGKDEQGQPVLVPRDTWRKTNIQILGLPGSGKSAMATNALIRCVRDFG
                     DAVVYFDPKGGRVGAARLPGALPGLHPAGSAAGETGAAESVPRSRPVRPEESAGCRV"
                     /name="type IV secretory system conjugative DNA transfer
                     family protein"
     gene            complement(4230..4376)
                     /locus_tag="I7S93_RS29375"
     CDS             complement(4230..4376)
                     /locus_tag="I7S93_RS29375"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_232254649.1"
                     /translation="MFNTDSLAWQWHIPELARQIYPWVSWLYREYYSLAGFFSGYRPVF
                     RSG"
                     /name="hypothetical protein"
     gene            5506..5655
                     /locus_tag="I7S93_RS29825"
     CDS             5506..5655
                     /locus_tag="I7S93_RS29825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001318239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_319922287.1"
                     /translation="MGCKQELPVQPDCCALSGNCSLESNPGKHAKTPLAAAIGNWEFAE
                     DLFS"
                     /name="replication initiation protein"
     gene            complement(5871..6023)
                     /locus_tag="I7S93_RS29380"
                     /old_locus_tag="I7S93_29175"
     CDS             complement(5871..6023)
                     /locus_tag="I7S93_RS29380"
                     /old_locus_tag="I7S93_29175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_232254650.1"
                     /translation="MKKGKDYFFFFILIVAGFLLAACQANYIRDVQGGTVAPSSSSELT
                     GIAVQ"
                     /name="colicin release lysis protein"
     gene            complement(6109..6366)
                     /locus_tag="I7S93_RS29385"
                     /old_locus_tag="I7S93_29180"
     CDS             complement(6109..6366)
                     /locus_tag="I7S93_RS29385"
                     /old_locus_tag="I7S93_29180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /GO_function="GO:0015643 - toxic substance binding
                     [Evidence IEA]"
                     /GO_process="GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E3-like toxin immunity protein"
                     /protein_id="WP_032440455.1"
                     /translation="MGLKLRLTWFDKKTEEFKGEEYSKDFGDDGSVIESLGMPLKDNIN
                     NGEFDLKKEWVPLLQPFFKNQIKPDVDNCYIAFDYRDGNW"
                     /name="colicin E3-like toxin immunity protein"
     gene            complement(6376..6537)
                     /locus_tag="I7S93_RS29390"
     CDS             complement(6376..6537)
                     /locus_tag="I7S93_RS29390"
                     /inference="COORDINATES: protein motif:HMM:NF020569.4"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]; GO:0043022 - ribosome binding
                     [Evidence IEA]; GO:0003723 - RNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E3/pyocin S6 family cytotoxin"
                     /protein_id="WP_232254643.1"
                     /translation="MAIKKRKIYEWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDP
                     KRNIKKYL"
                     /name="colicin E3/pyocin S6 family cytotoxin"
     gene            complement(6518..6790)
                     /locus_tag="I7S93_RS29395"
     CDS             complement(6518..6790)
                     /locus_tag="I7S93_RS29395"
                     /inference="COORDINATES: protein motif:HMM:NF020569.4"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]; GO:0043022 - ribosome binding
                     [Evidence IEA]; GO:0003723 - RNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E3/pyocin S6 family cytotoxin"
                     /protein_id="WP_232254644.1"
                     /translation="MNPYPEIRLHLPGRWRAGNKRRKKAKDAENKLNEEKNKPRKGTKD
                     YGHDYHPVPKTEDIKGLGELKRGDPKTPKQGGGGKRARWYGDKKT"
                     /name="colicin E3/pyocin S6 family cytotoxin"
     gene            complement(6699..6983)
                     /locus_tag="I7S93_RS29625"
     CDS             complement(6699..6983)
                     /locus_tag="I7S93_RS29625"
                     /inference="COORDINATES: protein motif:HMM:NF023002.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_269475550.1"
                     /translation="MQGLLFRKPIKKVKEAEANKDDFVTYNPPHEYGSGWQDQVRYLDK
                     DIQNQNEKLKAAQASLNAMNESLSRDKAALTGAMESRKQKEKKSEGCRK"
                     /name="hypothetical protein"
     gene            complement(6953..7177)
                     /locus_tag="I7S93_RS29630"
     CDS             complement(6953..7177)
                     /locus_tag="I7S93_RS29630"
                     /inference="COORDINATES: protein motif:HMM:NF023002.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_269475551.1"
                     /translation="MFLPPAQVKQRQEEEKRRQQAWDAAHPEEGLKRDYDKAKAELDAE
                     DKKYCDLKQPHCIDREGAPRCKGCCSGSR"
                     /name="hypothetical protein"
     gene            complement(7071..7331)
                     /locus_tag="I7S93_RS29405"
                     /old_locus_tag="I7S93_29190"
     CDS             complement(7071..7331)
                     /locus_tag="I7S93_RS29405"
                     /old_locus_tag="I7S93_29190"
                     /inference="COORDINATES: protein motif:HMM:NF015479.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_232254645.1"
                     /translation="MFRQRKPRQKALLLKKGDSRPAGFTAGGNSREAVIRFPKETGQKP
                     VYVSVTDVLTPGTGKTASGGRKASPAGMGRRSSGRGAEKRL"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            complement(7279..7842)
                     /locus_tag="I7S93_RS29410"
                     /old_locus_tag="I7S93_29195"
     CDS             complement(7279..7842)
                     /locus_tag="I7S93_RS29410"
                     /old_locus_tag="I7S93_29195"
                     /inference="COORDINATES: protein motif:HMM:NF015479.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_232254651.1"
                     /translation="MVVTAAIIAVALVADSLRPLRWPSVCLPWLLRGAEGLALSVSGDA
                     LSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSKIMTSLPADAVTETPAS
                     TLPLDQATVRVRQRVVDVVKDERQHIAVVAGRPMSVPVVDAKPTKRPGVFSVSIPGLPS
                     LQVSVPKGVPTAKAPPKGIVAEKR"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            complement(8173..9662)
                     /gene="ltrA"
                     /locus_tag="I7S93_RS29415"
                     /old_locus_tag="I7S93_29200"
                     /pseudo=""
     CDS             complement(8173..9662)
                     /gene="ltrA"
                     /locus_tag="I7S93_RS29415"
                     /old_locus_tag="I7S93_29200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226014.1"
                     /GO_function="GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /name="ltrA"
     gene            10308..10553
                     /locus_tag="I7S93_RS29420"
                     /old_locus_tag="I7S93_29205"
     CDS             10308..10553
                     /locus_tag="I7S93_RS29420"
                     /old_locus_tag="I7S93_29205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032440458.1"
                     /translation="MTHLKLTPAEEKRLADAFVAQALAMGLKGNKTLPKAVKQQVRERV
                     LRAIQDEREARRAQEMRREKYEATETTFTWQPQRRR"
                     /name="hypothetical protein"
     gene            10827..11198
                     /gene="tolA"
                     /locus_tag="I7S93_RS29425"
                     /old_locus_tag="I7S93_29210"
     CDS             10827..11198
                     /gene="tolA"
                     /locus_tag="I7S93_RS29425"
                     /old_locus_tag="I7S93_29210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237044.1"
                     /GO_component="GO:0098567 - periplasmic side of plasma
                     membrane [Evidence IEA]"
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein TolA"
                     /protein_id="WP_001237044.1"
                     /translation="MRLIPFILLALCSPLLLTACKHSTTQPPKIYTLDKSSKISSYAAA
                     IKTAVEMQMFEPEAYAGKMCTVRISIQRDGTLNSAIAEGGDPKLCKAAISAVTHAKIPP
                     APDENTWQIFKNAPLDFRP"
                     /name="tolA"
     gene            11195..11479
                     /locus_tag="I7S93_RS29430"
                     /old_locus_tag="I7S93_29215"
     CDS             11195..11479
                     /locus_tag="I7S93_RS29430"
                     /old_locus_tag="I7S93_29215"
                     /inference="COORDINATES: protein motif:HMM:NF015506.4"
                     /GO_function="GO:0015291 - secondary active transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB family protein"
                     /protein_id="WP_232254646.1"
                     /translation="MKAFTLTVLAAMFLTPVHAIPLKPVTTLQPTYPVQAAAKRIEGQV
                     TATFDILDDGRVDNVSLTGCHLFFRETLTAMRHWLYPAGHPAMRQGYKF"
                     /name="TonB family protein"
     BGC             2279..12001
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          5185..5768
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="97.611"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(1681..2408)
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="93.416"
                     /coverage="100.0"
                     /evalue="1.35e-140"
ORIGIN
        1 atgccacagg taacgatttc cgcgctggca cagcgcgatt tacaacgcct tcaggacttt
       61 ctcaaaacca aaaatcggct ggcagccaga aaaggaggtg aggtgatcgt ccgggctatc
      121 cagcaactga aaacattgcc agacattggc cgcccggtgc cgtttctgcc gctggaatat
      181 aaggaactgg tgatcgggtt tggcgacagt ggctatgtga tgctctaccg ccacgaccgg
      241 gaaatggacc agattgtgat cgtcaccgtc aggcatcaga aagaatccgg gtatccgggg
      301 gcagacagcc tctaataacc gatgacgggg gcgcaattca ttgcgtggcc gtcgccggtt
      361 tgacaagcgc agcgcgtcag aaaaaccaca tcctgaacgg aaaaacgggt aaaattcagc
      421 gatacattta ccgtgagaaa ttacacacct ttcacacccg ataaaatcag gggtatacag
      481 tggcgaaaac attgctcaac ctttcacagg cagcacaagc cgcgggcatt accagaagaa
      541 cgctatacaa tcatgtaaaa cagggaaagg ttaccgtgtc acgtgacggg aaaaacaacc
      601 ctgtcgtgga tgtgtcagaa ctgatccgtg tatacggaaa tgtgaatatc cctgagaaac
      661 aaattcccgg catttcacac cgtgaaaata cacaaaaaaa tttcccacag gaacagcttc
      721 tggcaatgca aaaggaactg gccgatctcc ggcaggctgt caccctgatg ctggaagata
      781 aaacatcccg ggaagaagaa cgccgccagc acgatgatga gcgccggaaa ctccaggccg
      841 aagtggacag attgacaaca gaactgacac agaagaaaaa acgcttctgg tccggctggt
      901 ttagctgaga acttaccgaa gggaatggag aacatgacga agcaggaaaa aactgccctc
      961 aatatggcta aattcattaa ggatcagtcg ctgctgttgc tggaaaagct gaacgagctg
     1021 gacatggata ccccggccga catgtgcgaa cggcttcacg aggatgcgga aacactctgg
     1081 caggtgatgc gggataagct cggggaagaa taacagcacc ggccatgccg gtgctggcgt
     1141 tattttttgc cgaacggcca ccaccggcgg gcgggtttgt cctccggcag ttcaggcacc
     1201 ggcacgttaa aatagcggct gttatattcc cgcatcagct ccgctttcag cttctcgttc
     1261 accgcgcttt ccccgtgccg ctcgctgacc acctcaatca tcgcgttaat ctgctccggt
     1321 gagcacttcc cggcatcaac cacctgcaca ccgttctcga tggcgaaccg ctccaccttt
     1381 cgatagaggt aatcacacag cttcattcct gtgggtttgt cccgttccca ttgcggattt
     1441 tcaccggtga aaaagtacgt ggctttttcg tcgctgttga gccgctcgtc atacatcccg
     1501 atggatttca tcatcgccag atgctgggcc cggtcgacaa aacagaaaac atacgccccg
     1561 gtctgccagg cgagcaccac catgtcttcc agatgctcgc tggttggcat aatgcagcgc
     1621 tcgccgtctt tgtcttccac gtcctcaata aataccatgt acagcgccat aatccctcac
     1681 tccgttgtca taaatttaaa gcacgcgaac agcctctccc ggtccagctc caccgttttg
     1741 cgggcctcgc cggtctgtgg attcacgatt tcatccaccg ccagaatcgc ccgctgtacc
     1801 cggacaagcg tcggccggtc agggcagatg taccagattt catcgatgcc gttcgcccgg
     1861 cggttgaaca gatacccgga caccacttcc tgataccgcc tgcggctctt gacggtgcgc
     1921 tctacctcaa atgccaccgt tctgccgtcc agctccgcca gcgcgtccgg cactttcatc
     1981 cctttcaggg ccatacggtg caggtaccgc cagccggtgg ccccccggcc ctccatggag
     2041 aggcgcaggg actgcacggc cagccggtgc ggcagctgcg ccgccgacac ccttgacggc
     2101 tgaaacggaa taacgtccgt cagcggctcg tcctcgtcga acgagaacgc caccccgtgc
     2161 ggcgtcagcc cccacacgct gacctgacgg ccgtcaaccg ggtatttcgc ccggaccagc
     2221 agccctttcg ccaccagact gtccaggaag cggtaaaccg gctgtaccgc cgcaatcccc
     2281 agccgtcgcg caaccagctc cgccgtggaa cacagctctt cccgcagcca gcgcagggtc
     2341 agccgtgttt tctccgcgtt ccgcgcctgc cgcttcgcgt ggctgacgtt gtactgctcc
     2401 agtgtcatca gtaaagcccc gcaaaatcat catccgcttt tggtccgccg ccgtcggccg
     2461 gaggcaggta ctccgccagc gggtccgttt tcgccagcac cgggaaggtt ttcagcgaaa
     2521 tttcccggcg ctcaacccgc agcgggctgc tgaacgccag ccgcgccacg cccagcccgg
     2581 tcatcaccgc gaacccgtca ggcaggtgtt gcagggtgtt cacgtcaaac agcggccgcg
     2641 cctccttctg gatgaagctg tcgccgctga tgtgctccac gttccccgcc tcccggctgg
     2701 cccggcggcg ctccacgtcc acccggatct ccccggtctg gcccgccgcc cactgcgcgg
     2761 actcctggct ggccgcgcga tagaaccagc ggatcggcgt gttatccagt accgtggttt
     2821 tcacaaaatc agcgggcaga tcctgcccgc actgaccgaa gtcgcccagc gactggtgcg
     2881 cgagcagcag gttgcagtcc cggctgcgca gcgtccccag cgcgttcagc acgtacttcg
     2941 acagcagata tttaatctca tcgagcatga tgctcgcgtg cggccacctc cggaactcat
     3001 cccgcgcaat gatgatttgc gcgcagcggg caaacagcat cttctgcacc cggatcaccg
     3061 cctcatcgtc catcgagccg atgacgtaca ggcagccgcc gccgttgatt atccccgcca
     3121 catcgatacc gctgtccgtc tgcaggacgc tcaggtcggc cacgttctcc agcttggtga
     3181 tcagcccctt cacgtccttt ttcagggcct ccggcaacgc gtacgccgcc gccagcacct
     3241 gctgaatgtt tgcccccctg cgggaactgc tccgcaatca gcttcgccgc tttctgctcg
     3301 ctgatgcggt agtggtccgc cacgtcgccg gtctcactca ggttaaaccc ggcaaccagc
     3361 agattcttca gggcgtactg gtcgagatcg cggaacagat tcagctgcgc cggtttcccc
     3421 ggccgcagat ccagcagggt gaagtccggg cagtgcgccc ggaagacgtg cggcgcccac
     3481 gcgtccccct ttggggtcga agtacaccac agcgtccccg aaatcgcgta cgcagcgaat
     3541 gagcgcgttg gtggccatcg cgctcttgcc gctcccgggc aggccgagga tctgaatatt
     3601 ggtcttgcgc caggtatcac gagggaccag caccggctgg ccctgctcat ccttacccag
     3661 aaacaccgcc tgctgtttcc gggcctgctc cgtggaaaaa tcggccagcg cgttaaccgg
     3721 taccggctcc ccgaaatgca ggtggcggac gtctgtcatt tctccggtcc gctggctgct
     3781 gcgccggctc tcctgattca gtttcgcgtt caccgcctcg tcagcggccg caaaatgacc
     3841 atcaagcagc aggaacgcca gcagccgcgc cagaaggacg ccggcgacaa gccctccggc
     3901 acaccaggct atcccgaaca ggttagccgg ctgcagcagg taataatctg cgttcgcata
     3961 gaggtccggg cgcaggacgg tttctcccca gctctcgata aacacggcga caaccagccc
     4021 cccccagaag ggccagaccg gcagcgccgg tcagccagta cgcgtagttc cagacatgtc
     4081 gccgtgccct gaccatccgc ccgggtgaat ccagcgaggc cagcaccgaa aatggcacag
     4141 tccggttatt atcgcgctta tagcgatcgg catactcccg ccgcgcctta tggctcagcc
     4201 ccacaaaacg cattcggccg gcccagagtt cagccagacc gaaaaacagg ccgataacca
     4261 gaaaaaaacc cggccagact gtaatactcc cggtacagcc agctgaccca cgggtaaatc
     4321 tgccgggcca gctccgggat atgccactgc caggcaagcg aatccgtatt aaacatgcaa
     4381 tctctctcct tcagacgacg ggtttaccgg cgtgatgcgc agcccccgct gcacaagccg
     4441 cggacatgcc cccaaggcat ggcggcggcg gtcacgtccg tggtgattgc gttcagcttt
     4501 caccgcggag gccagcctct ttccgcccca tgcggaaaaa ggcgcagccc cggaggaaca
     4561 acgagcacgc cccagcgtgt gagaggaaaa ggcggcaccc cagtgcggtc tttttccggt
     4621 gttccggccc cccgtcagag ttcgccatag cgagcggctg accacccgca aaatcaggag
     4681 cagctttgct gcttcgtcag gtgcgtccag caccgtggat ttttgtgggt ggtcaggcgt
     4741 gagcctgacg gggggccggg tgaatttctg gcgtggccgg cgtccagccg gacagagcca
     4801 gaaagagggg aaaaagaccg tgcgtcggtg gcgtccagcc agcgtaagca aggtcttttc
     4861 ccctgaagtc agccacgccc cagcggggat gacttgcatt tctccgcaag gagaaaaaag
     4921 caacagagat aggttaacgt aaaatgttca gcgaaaaacc gacatggttc acctatcctg
     4981 ataattgatc gtcagggaat agaaagactt aatcagggga caatatccca catcagcgcg
     5041 tccggtgacc gtcttgcagg tgccggggaa attgcgcctc ctcgctcact cggtcgctac
     5101 gctccgggcg tgagactgcg gcgggcgctg cggacacata caaagttacc cacagattcc
     5161 gtggataagc aggggactaa catgtgaggc aaaacggcag ggccgcgccg gtggcgtttt
     5221 tccataggct ccgccctcct gccagagttc acataaacag acgctttttt cggtgcatct
     5281 gtgggagccg tgaggctcaa ccatgaatct gacagtacgg gcgaaacccg acaggactta
     5341 aagatcccca ccgtttccgg taggtcgctc cctcttgcgc tctcctgttc cgaccctgcc
     5401 gtttaccgga tacctgtccg ccgttctccc tttgcgggaa gtgtggcgct ttctcatagc
     5461 tcacactact ggtatctcgg ctcggtgtag gtcgttcgct ccaagctggg ctgtaagcaa
     5521 gaactccccg ttcagcccga ctgctgcgcc ttatccggta actgttcact tgagtccaac
     5581 ccgggaaagc acgcaaaaac gccactggca gcagccattg gtaactggga gttcgcagag
     5641 gatttgttta gctaaacacg cggttgctct tgaagtgtgc gccaaagtcc ggctacactg
     5701 gaaggacaga tttggttgct gtgctctgcg aaagcccagt taccacggtt aagcagttcc
     5761 ccaactgact taaccttcga tcaaaccacc tccccaggtg gttttttcgt ttacagggca
     5821 aaagattacg cgcagaaaaa aaggatctca agaagatcct ttgatctttt ctactgaacc
     5881 gcgatccccg tcagttcaga ggaggacgat ggtgccaccg ttccgccctg aacatcccgg
     5941 atataatttg cctgacatgc ggccagaaga aagccagcaa caatcaatat aaaaaagaaa
     6001 aaatagtctt tacctttttt catatacttt ccctgtattt aaagactccg gcattcatcc
     6061 ctgaacaccg gaagtcagta tttcaaatca tccttgataa tttttttgtt accagttacc
     6121 gtcccgataa tcaaaagcta tataacaatt atccacatca ggttttattt gatttttaaa
     6181 aaatggctgt agtaaaggaa cccattcttt cttcaaatca aactcaccat tattaatatt
     6241 atcctttaaa ggcattccca agctttcaat gacagaacca tcgtcaccaa agtctttaga
     6301 atactcttcc cctttaaact cttcagtttt cttatcaaac catgtcaaac gtaatttaag
     6361 ccccatattt acctctcaaa gatatttttt aatgttccgt tttggatctg gccctttaac
     6421 ctgcttaccc gttttgggat caaatgcgcc taggtgttcg ccatcactgg cacgataccc
     6481 ttcaagctca ccgtgctggg aatcccattc ataaatttta cgttttttta tcgccatacc
     6541 atcgggcccg cttaccacca ccaccttgtt taggtgtttt aggatcacct cgctttaact
     6601 ctccaagtcc ctttatgtct tctgttttag gtactggatg ataatcatgg ccgtagtctt
     6661 tagtcccctt gcgaggcttg ttcttttcct catttaactt attttctgca tccttcgctt
     6721 tttttctcct tttgtttccg gctctccatc gccccggtaa gtgcagcctt atctctggat
     6781 aaggattcat tcattgcgtt taaagatgcc tgagccgctt ttaatttctc attctgattc
     6841 tgaatatcct tatcaagata gcgaacctga tcctgccacc cggagccata ttcatgaggc
     6901 gggttataag tcacaaaatc atctttattt gcctctgcct cttttacctt ttttatcggc
     6961 ttcctgaaca gcagcccttg caccggggag cgccttctct gtcgatgcaa tgcggctgtt
     7021 taaggtcgca atatttttta tcttcggcat ccagctcagc tttcgcttta tcatagtctc
     7081 ttttcagccc ctcttccgga tgagcggcgt cccatgcctg ctggcgacgc ttttcttcct
     7141 cctgacgctg ttttacctgt gccgggggta agaacatctg tcaccgacac ataaaccggc
     7201 ttctgtccgg tctctttcgg gaaacgaata acggcctcac gggagttacc accggctgta
     7261 aaaccagccg gacgtgaatc accttttttc agcaacaatg ccttttggcg gggctttcgc
     7321 tgtcggaaca cctttcggta cgctcacctg cagagacggg agacccggaa tcgacacact
     7381 gaataccccc ggacgttttg tcggtttcgc atccaccaca gggacactca ttggccgacc
     7441 tgcgacaacc gcaatatgct gccgctcatc cttcaccaca tccacaaccc gttgtctgac
     7501 acgaaccgtc gcctggtcca gtggtaaagt acttgccgga gtctccgtca ccgcatcggc
     7561 cggtaatgac gtcataattt ttgacatcat tttcggatca tcttttgcaa tctcagaagg
     7621 cagcacaccg tagatcgcaa tcccccacag accaaactta aacggcccct tcagggcagc
     7681 cagcacatca gcaacggcgg ccgacaacgc atcgccggaa actgataaag ccagtccttc
     7741 agccccccgg agtagccagg gcaggcagac cgaaggccat cgcagtggcc gaagactgtc
     7801 cgccaccaga gctaccgcta tgattgccgc tgttaccacc attaccaccg ggtttactcc
     7861 cgccgttacc aaactccccc ggattatagt tatgaatatc tccattcggc gtatgcgtcg
     7921 taccccagcc cggcccgctg tttggatccg taccaccacc tgatgaaggg ccacctttac
     7981 cagacgtacc gttcacattc ccactggcct gaccaccatt atgtcccaga cctgaattac
     8041 ccggacctcg accgtctcca ccactcatac cgttttcctc tttgacattt aaaacaataa
     8101 attaaagcca acatgtcgcg gtagggatac ccgttaccgg ataccccccg cacagatccc
     8161 ggcgtgcgcg atttacgcac cgggctcctg cctcgggtgt ctggcggtga accgctccac
     8221 aggccatgga tgaagaaccc gaacccttgg tagccatgcg gctgccagtt tgtttgcttt
     8281 cgtccaggtc gtatcatcct tctggctcct gcgcctgagc gcccggcgcc agaggtttgt
     8341 tacgtgtgtc ctgaacttct gcatggtggg gaagttgccc ggtaccgagt gatagttcag
     8401 gtatccctga accactctcc tgagccattt tccctgttcg gggattgagt aatgccagcg
     8461 ccttcgcaga ccgtctttga tggctttcag agttgccgtc atccgatccc ggcgggtctt
     8521 tcgtatcagc atgaacctgc cgttgcgatc tttcccgctg atgtgcgtga acccgaggaa
     8581 gttgaacgtt tctggtttgc ctttttcccc ctgatggcac ggttttcggc agcgaagcgg
     8641 ccgaactcca tcagacgggt tttctccggg tgaaccgtga gtccgaactc cctcagtctg
     8701 cgctgcatgg ctatacggaa gcgccgggca tcgtatcgtt tgtcgaaccc gatgacgatg
     8761 tcatcggcgt atctgaccat taccacattg cctgtggcat agcgacgtcg ccactgatgc
     8821 gcccacagat cgaagacgta gtggaggtat atgtttgcca gcagcggtga gatgaccgca
     8881 ccctgtgggg tgccttcctc cgttgctcgc cattgaccct cctccgacgt cccggctgtg
     8941 agccacttac gtatgagcct gattaccctc cggtcgccga tccgatgctc tgtgaacctg
     9001 atcagccatt cgtggctcac cctgtcgaag aactgactga tgtcggcatc cagtacccag
     9061 tttacgttag tgcgtaccag ccctgtggcc agtgcgtcca gtgcatcgtg ctggcttcgc
     9121 ccgggtctga acccgtatga gaaccccata aagtcgtttt catagactgc gttcaggatt
     9181 ttcaccagcg catactggac gatcttgtcc tccagcgagg cgatgccgag cgggcgttgt
     9241 tttccatccg cttttgggat gtagtgacgc ctgccgggct gcgccctgta gctgccctga
     9301 tgtagcctcc ggtgcagatc tgttatgttg ttcttcatgt ttccggcgta gtccatccac
     9361 ctgatgccat ccactccggc ggccgctttc ctgctcaggg agaggaatgc ggcttccagt
     9421 gcttcgactg tcagcaggtg gaacaatgct gtaaaccgtt ctttcttccg ctgcttcgca
     9481 gcttcccgca cgcgtgacag cctctgtgac atgctttccc ggctctgtgt ccggcgcatg
     9541 tgtggctgtt ccgcgttccc cttggccccg ctccttcgct ccactgactc cgctcctttc
     9601 gggttgttcg cctgcttcgc cgctactatg agcgagtccg acttctcctc tccgtacatc
     9661 accggctatg actcctcgtc ttcccggtgc gggccatctc cgacactggc agatggtcag
     9721 aggggagatc tcccggttcc cgcgtagaga tcgtattgac atgccagggt ctcagacccc
     9781 gccgggtcca tgtggcactc gcagtgtcgc accctatgat gttgccttcc gttaacagta
     9841 caacgtcggc acccggtaat ttaatataca tttcgtggct caatggctgg cctgtcaaca
     9901 cccctgtcaa cgcttcgccc catacctcgc ggtatgcaac gcatgactcg gggaccttgt
     9961 ggattgctgg tccttcaatg gtcggggact ttcacccctt gatctctaac cggtctcccg
    10021 gcgcacactg tacatataca cagtataatt attaccttac tcctcccgtt ttcaggtgtc
    10081 aatatatgag attagttctc atcttcaggc acaaaaaaag cgcccggagc cacctgtaag
    10141 cagatcgcgt cttttcccga aaatttctca tggcaacaaa ttttattatt taagacattc
    10201 atcacactta catttcagat ggtatagaca catctgaaag ctaactggca tgaggagagg
    10261 acctgcggtt aaactgttcg ggaaacctga gacgcccgga ggccactatg acgcacctga
    10321 aactgactcc cgctgaagaa aagcgcctgg cggacgcctt tgtcgctcag gcactggcca
    10381 tgggcctgaa agggaacaaa acgctgccaa aggcggtaaa acaacaggtg cgggaaaggg
    10441 tgcttcgtgc cattcaggac gaacgtgaag ccaggcgggc gcaggaaatg cgtcgggaga
    10501 aatacgaggc tacggaaacc accttcacct ggcagccaca gcgccgccgg taaggggtat
    10561 ttaccataac gtcgcattgc ccgcaccgct cagacggtct gagggcgttt ccggcggcta
    10621 cgggataaaa caggcaacaa accacccgga aaaccgccgg aaacgcgccc ggtaaattgt
    10681 aacccgctgc atgcctatgc acgcaactgc atggcgggcc gtttggtgta aaaacgatac
    10741 gataagccgt gtttatgtaa atgaacgtgg ccgtaaagag tgacaaatat acatgtaaca
    10801 ttttttactg acaggtcatc aacccgatgc gtttaatacc ctttatcctg ctggcattgt
    10861 gcagcccctt actcctgacg gcctgtaagc attccaccac ccagccgccg aaaatttata
    10921 ctctggataa gtcatctaaa atcagtagct acgctgcggc catcaagacc gctgttgaaa
    10981 tgcagatgtt tgaaccagag gcctatgcgg gaaaaatgtg caccgtgcgg atatccatac
    11041 aacgtgatgg cactctgaac agcgccattg ctgaaggagg agatccgaaa ctctgtaaag
    11101 cagcaatatc agccgttacc cacgccaaaa ttccgccggc accggatgaa aatacctggc
    11161 aaatattcaa aaacgcccct ctggatttca gaccatgaaa gcttttactc tgacagtgct
    11221 ggcggccatg ttcctcactc cggtacatgc gataccacta aaacccgtaa ccacactgca
    11281 gccaacctac ccggtacagg ccgcagcaaa acgcatcgaa ggtcaggtga ccgccacgtt
    11341 tgatattctg gacgatggac gagtggacaa cgtgtcgctt accggctgtc accttttttt
    11401 tcgggaaacg ctgacggcaa tgaggcactg gctatatccc gcagggcacc cggcaatgcg
    11461 acagggttat aaattttgaa ttcagtctga aaaatgacgg cttacaggat ccgcgaccag
    11521 tcaccaccca aaagctcaat gatgatggtt gccgccagta acaggtcctt taacccgcag
    11581 gctgcaatag tcctggatga tgagtgagcc tgtagcagcc ctgattagtg gaagcgaagc
    11641 tgaaaaatgg gcagcaaaag ccgtatttct ggcaaatagc gccgccacgg attaaagtag
    11701 tcatgtgtaa tacatatgac tacaaagggg cttttatgtc atcagcaaca tccatcaggc
    11761 tcgatgaaga acttaaggac cggctgaaaa cgctggccga tgaccggcac cgctcagcgc
    11821 acgcgctaat gctggaggca atcaccgaat acatcgaccg ggaagagaag cgcagccagt
    11881 acctgcggga cggacaggcc gcatggcagc actatcagga aacgggtctg caccttactg
    11941 cggaagaagc ggaagcctgg ataagtacct ggggaactga gaacgagcag gatgctccgc
    12001 c
//
