LOCUS       NZ_CP065550            44323 bp    DNA     circular CON 14-FEB-2024
DEFINITION  Enterococcus faecium strain Dallas 1 plasmid p1_44kb, complete
            sequence.
ACCESSION   NZ_CP065550
VERSION     NZ_CP065550.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN17012772
            Assembly: GCF_015999605.1
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44323)
  AUTHORS   Islam,M.J.
  TITLE     Molecular characterization of VREfm isolates from Dallas, Texas
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 44323)
  AUTHORS   Islam,M.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2020) Biological Sciences, University of Texas at
            Dallas, 1520 Richardson Dr Apt 1418, Richardson, TX 75080, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2019
            Assembly Method                   :: Unicycler v. 0.4.7
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 30.0x
            Sequencing Technology :: Oxford Nanopore MinION; Illumina NextSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/14/2024 02:49:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,130
            CDSs (total)                      :: 3,039
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 5, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 5, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 40 of 112
            Pseudo Genes (incomplete)         :: 66 of 112
            Pseudo Genes (internal stop)      :: 30 of 112
            Pseudo Genes (multiple problems)  :: 20 of 112
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP065550.1.
            Bacteria and source DNA available from Dr. Kelli Palmer, UTDallas.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..44323
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /strain="Dallas 1"
                     /isolation_source="Rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /plasmid="p1_44kb"
                     /geo_loc_name="USA: Dallas"
                     /collection_date="2015"
     gene            1..1041
                     /locus_tag="I7089_RS15205"
                     /old_locus_tag="I7089_15205"
     CDS             1..1041
                     /locus_tag="I7089_RS15205"
                     /old_locus_tag="I7089_15205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_000997689.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLLK
                     DRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGRVN
                     KRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTTVIA
                     KIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVDIMKE
                     DSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELESYGIDA
                     DKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFNELPTVS
                     TENWLE"
                     /name="replication initiator protein A"
     gene            complement(1657..2337)
                     /locus_tag="I7089_RS15210"
                     /old_locus_tag="I7089_15210"
     CDS             complement(1657..2337)
                     /locus_tag="I7089_RS15210"
                     /old_locus_tag="I7089_15210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_002287920.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIGADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            2483..2566
                     /locus_tag="I7089_RS15215"
                     /old_locus_tag="I7089_15215"
     CDS             2483..2566
                     /locus_tag="I7089_RS15215"
                     /old_locus_tag="I7089_15215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]; GO:0031556 - transcriptional attenuation by ribosome
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="WP_001814874.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
                     /name="23S rRNA methyltransferase attenuation leader
                     peptide"
     gene            2691..3428
                     /gene="erm(B)"
                     /locus_tag="I7089_RS15220"
                     /old_locus_tag="I7089_15220"
     ARG             2692..3425
                     /name="erm(B)"
                     /gene="erm(B)"
                     /gene_name="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /tool="amrfinderplus"
                     /drug_class="LINCOSAMIDE/MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            <3598..3858
                     /locus_tag="I7089_RS15225"
                     /old_locus_tag="I7089_15225"
                     /pseudo=""
     CDS             <3598..3858
                     /locus_tag="I7089_RS15225"
                     /old_locus_tag="I7089_15225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /GO_component="GO:0005694 - chromosome [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
                     /name="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            4021..>4686
                     /locus_tag="I7089_RS15230"
                     /old_locus_tag="I7089_15230"
                     /pseudo=""
     CDS             4021..>4686
                     /locus_tag="I7089_RS15230"
                     /old_locus_tag="I7089_15230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
                     /name="IS1182-like element IS1182 family transposase"
     gene            4722..4967
                     /locus_tag="I7089_RS15235"
                     /old_locus_tag="I7089_15235"
     CDS             4722..4967
                     /locus_tag="I7089_RS15235"
                     /old_locus_tag="I7089_15235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="WP_000567888.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRLL
                     LGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
                     /name="single-stranded DNA-binding protein"
     gene            5070..5939
                     /locus_tag="I7089_RS15240"
                     /old_locus_tag="I7089_15240"
     CDS             5070..5939
                     /locus_tag="I7089_RS15240"
                     /old_locus_tag="I7089_15240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing protein"
                     /protein_id="WP_000228166.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIYY
                     NSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIKRV
                     EQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETYPNA
                     LQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYCINEK
                     KAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINNFLNEE
                     SSDERKQI"
                     /name="nucleotidyltransferase domain-containing protein"
     gene            5920..6654
                     /locus_tag="I7089_RS15245"
                     /old_locus_tag="I7089_15245"
     CDS             5920..6654
                     /locus_tag="I7089_RS15245"
                     /old_locus_tag="I7089_15245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]; GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_000662263.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGKR
                     VLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDFPE
                     ESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNEKGE
                     ILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPENMMD
                     IPGMADEMRRPMMLIVSAKKKM"
                     /name="class I SAM-dependent methyltransferase"
     gene            6687..7595
                     /gene="ant(6)"
                     /locus_tag="I7089_RS15250"
                     /old_locus_tag="I7089_15250"
                     /pseudo=""
     CDS             6687..7595
                     /gene="ant(6)"
                     /locus_tag="I7089_RS15250"
                     /old_locus_tag="I7089_15250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="ant(6)"
     gene            7592..8134
                     /gene="sat4"
                     /locus_tag="I7089_RS15255"
                     /old_locus_tag="I7089_15255"
     ARG             7593..8131
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            8227..9021
                     /gene="aph(3')-IIIa"
                     /locus_tag="I7089_RS15260"
                     /old_locus_tag="I7089_15260"
     ARG             8228..9018
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(9164..10456)
                     /locus_tag="I7089_RS15265"
                     /old_locus_tag="I7089_15265"
     CDS             complement(9164..10456)
                     /locus_tag="I7089_RS15265"
                     /old_locus_tag="I7089_15265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1251 family transposase"
                     /protein_id="WP_000122610.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIYT
                     AQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADTSV
                     AKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTPLPK
                     VLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREAVEWI
                     VIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQKHYQLG
                     KQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQLYQDFL
                     YAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPLECLNNHI
                     KVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
                     /name="ISL3-like element IS1251 family transposase"
     gene            10804..11346
                     /locus_tag="I7089_RS15270"
                     /old_locus_tag="I7089_15270"
     CDS             10804..11346
                     /locus_tag="I7089_RS15270"
                     /old_locus_tag="I7089_15270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="WP_002321977.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLEE
                     AGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAMYK
                     IKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPASGG
                     QEPESRMIEPVLLQSFK"
                     /name="HTH domain-containing protein"
     gene            complement(11376..12056)
                     /locus_tag="I7089_RS15275"
                     /old_locus_tag="I7089_15275"
     CDS             complement(11376..12056)
                     /locus_tag="I7089_RS15275"
                     /old_locus_tag="I7089_15275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            13372..14391
                     /locus_tag="I7089_RS15280"
                     /old_locus_tag="I7089_15280"
     CDS             13372..14391
                     /locus_tag="I7089_RS15280"
                     /old_locus_tag="I7089_15280"
                     /inference="COORDINATES: protein motif:HMM:NF019371.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="WP_010729551.1"
                     /translation="MKTSNRKYKVKTVNHRIPPKKALCVINNSKVINQELKPYLSEQEM
                     IKKISKDIFLTNSDTILLEKFLKKNSYFRFSIYVKLMKNIDKVTILDVIETYKLDSFIR
                     NQLHYFVNQIEIFWKKSLSDNMCVSYEETSIFPKNQCYLDKNIYSDLKWAEDIIGHFNS
                     FFYSNQSPTFKHHHIKKNHCLPIWALFEEITFGSLTTFINQLNTEYYNNWVMSCYDNPK
                     YKKAIRSWANVIRAYRNKIAHHSRIYAFKVTDAPTIIKNDSKSYFPENNLKETQKLYLY
                     GGLYVIKHLLIYEDSMTQTLWNKFLIDLEKKIDKIPSLEKSNYGFPENWRNKLKIMIV"
                     /name="Abi family protein"
     gene            complement(14893..15309)
                     /locus_tag="I7089_RS15285"
                     /old_locus_tag="I7089_15285"
     CDS             complement(14893..15309)
                     /locus_tag="I7089_RS15285"
                     /old_locus_tag="I7089_15285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002305824.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDVNNYSEAIRFLCMSYE
                     PDTNTTTTSNQAKLNAMGKEISIMTEIMAEFADLYLKDTGVLIGTNSKVYQEVKEKIEN
                     QLNPSRRNQPKNRQKETNQTFTSGNFDPTNFLKR"
                     /name="hypothetical protein"
     gene            complement(15311..15592)
                     /locus_tag="I7089_RS15290"
                     /old_locus_tag="I7089_15290"
     CDS             complement(15311..15592)
                     /locus_tag="I7089_RS15290"
                     /old_locus_tag="I7089_15290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000353845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000353845.1"
                     /translation="MDILVRNINPKIITRIDKRCQELTTKTGKKWSRNQYLKILIENDF
                     DHELMNYKKDQFDLLFEKFIAIQAENTNILNDYVHTNNQLIETLIGGI"
                     /name="hypothetical protein"
     gene            complement(15968..16492)
                     /locus_tag="I7089_RS15295"
                     /old_locus_tag="I7089_15295"
     CDS             complement(15968..16492)
                     /locus_tag="I7089_RS15295"
                     /old_locus_tag="I7089_15295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_002305828.1"
                     /translation="MTEKTIKELAEELGVSKTAINKKVSDENRKLWFSKIGNKFVINET
                     GQKAIKSMFFNENENSNQQLVGEKTKTENHKNANQVPELEVLSLLEQQLNQKDMQLQEK
                     DEQIKQMQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENKSTTLSEETESIEKQS
                     KTEKKWWQFWQ"
                     /name="DUF536 domain-containing protein"
     gene            complement(16509..>17390)
                     /locus_tag="I7089_RS15300"
                     /old_locus_tag="I7089_15300"
                     /pseudo=""
     CDS             complement(16509..>17390)
                     /locus_tag="I7089_RS15300"
                     /old_locus_tag="I7089_15300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332718.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /name="replication initiation protein"
     gene            complement(17446..18126)
                     /locus_tag="I7089_RS15305"
                     /old_locus_tag="I7089_15305"
     CDS             complement(17446..18126)
                     /locus_tag="I7089_RS15305"
                     /old_locus_tag="I7089_15305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            18409..19104
                     /gene="vanR-A"
                     /locus_tag="I7089_RS15310"
                     /old_locus_tag="I7089_15310"
     ARG             18410..19101
                     /name="vanR-A"
                     /gene="vanR-A"
                     /gene_name="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            19082..20236
                     /locus_tag="I7089_RS15315"
                     /old_locus_tag="I7089_15315"
     CDS             19082..20236
                     /locus_tag="I7089_RS15315"
                     /old_locus_tag="I7089_15315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-A"
                     /protein_id="WP_002305818.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGKL
                     GDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKYFD
                     EINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVMYLA
                     HDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRYNLQT
                     ITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFNNILKN
                     AAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSSDTGGAG
                     LGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
                     /name="vancomycin resistance histidine kinase VanS-A"
     gene            complement(20334..21626)
                     /locus_tag="I7089_RS15320"
                     /old_locus_tag="I7089_15320"
     CDS             complement(20334..21626)
                     /locus_tag="I7089_RS15320"
                     /old_locus_tag="I7089_15320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1251 family transposase"
                     /protein_id="WP_000122610.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIYT
                     AQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADTSV
                     AKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTPLPK
                     VLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREAVEWI
                     VIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQKHYQLG
                     KQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQLYQDFL
                     YAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPLECLNNHI
                     KVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
                     /name="ISL3-like element IS1251 family transposase"
     gene            21958..22926
                     /locus_tag="I7089_RS15325"
                     /old_locus_tag="I7089_15325"
     CDS             21958..22926
                     /locus_tag="I7089_RS15325"
                     /old_locus_tag="I7089_15325"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="WP_001059542.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKSA
                     PFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAYSP
                     DSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKAVIE
                     RLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQRMKQ
                     GAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQFLLKL
                     QRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
                     /name="D-lactate dehydrogenase VanH-A"
     ARG             22902..23950
                     /name="vanA"
                     /gene="vanA"
                     /gene_name="glycopeptide resistance gene cluster; Van
                     ligase"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="99.71"
                     /coverage="101.75"
     ARG             22920..23947
                     /name="vanA"
                     /gene="vanA"
                     /gene_name="D-alanine--(R)-lactate ligase VanA"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="99.71"
                     /coverage="100.0"
     gene            23956..24564
                     /locus_tag="I7089_RS15335"
                     /old_locus_tag="I7089_15335"
     CDS             23956..24564
                     /locus_tag="I7089_RS15335"
                     /old_locus_tag="I7089_15335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="WP_000402348.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTYE
                     LAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRTEM
                     ISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEAQNR
                     RRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
                     /name="D-Ala-D-Ala dipeptidase VanX-A"
     gene            24992..25903
                     /gene="vanY"
                     /locus_tag="I7089_RS15340"
                     /old_locus_tag="I7089_15340"
     CDS             24992..25903
                     /gene="vanY"
                     /locus_tag="I7089_RS15340"
                     /old_locus_tag="I7089_15340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="WP_000732308.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHLE
                     NSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLLDS
                     NIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGYSEH
                     NSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIRYVGL
                     PHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNLRYEIS
                     GNNIDGVIVTVFPGSTHTNSRR"
                     /name="vanY"
     gene            26056..26541
                     /gene="vanZ-A"
                     /locus_tag="I7089_RS15345"
                     /old_locus_tag="I7089_15345"
     ARG             26057..26538
                     /name="vanZ-A"
                     /gene="vanZ-A"
                     /gene_name="glycopeptide resistance protein VanZ-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(26828..27157)
                     /locus_tag="I7089_RS15350"
                     /old_locus_tag="I7089_15350"
     CDS             complement(26828..27157)
                     /locus_tag="I7089_RS15350"
                     /old_locus_tag="I7089_15350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000754864.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIKI
                     FYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDILS
                     AIRVF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            27462..27791
                     /locus_tag="I7089_RS15355"
                     /old_locus_tag="I7089_15355"
     CDS             27462..27791
                     /locus_tag="I7089_RS15355"
                     /old_locus_tag="I7089_15355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000629052.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEPK
                     KEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEELA
                     AEIGL"
                     /name="hypothetical protein"
     gene            27781..28068
                     /locus_tag="I7089_RS15360"
                     /old_locus_tag="I7089_15360"
     CDS             27781..28068
                     /locus_tag="I7089_RS15360"
                     /old_locus_tag="I7089_15360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_000312841.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQK
                     TGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(28347..28910)
                     /locus_tag="I7089_RS15365"
                     /old_locus_tag="I7089_15365"
     CDS             complement(28347..28910)
                     /locus_tag="I7089_RS15365"
                     /old_locus_tag="I7089_15365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000017403.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAVR
                     PQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTPHG
                     RLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQVYS
                     VKEITEMTGISKATLYRYLKDNRE"
                     /name="recombinase family protein"
     gene            29553..30506
                     /locus_tag="I7089_RS15370"
                     /old_locus_tag="I7089_15370"
     CDS             29553..30506
                     /locus_tag="I7089_RS15370"
                     /old_locus_tag="I7089_15370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="WP_000222571.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNFL
                     KCGGTALEYFEQYKENKRRCGRTEIIFPAEEKEYIEKRSTEGWTPDVIIGRAERTFSCS
                     ISTLYRRFKTGEFNVLHLPMQGKRKPNGYKEKRGKQAFKRNISERKKDYVVFEEEFGHL
                     EGDTIVGIHHKSAVITLVERLSKAIIVLKPEGRKAVDIENSINEWLQSVPKNLFKSITF
                     DCGKEFSNWKSISNTNDIDIYFADPGTPSQRGLNEHSNGLLRKDGLPKEMDFNQVNQGF
                     ISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA"
                     /name="IS30 family transposase"
     gene            30484..31959
                     /locus_tag="I7089_RS15375"
                     /old_locus_tag="I7089_15375"
     CDS             30484..31959
                     /locus_tag="I7089_RS15375"
                     /old_locus_tag="I7089_15375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="WP_000443455.1"
                     /translation="MESFVSLNLTNNTSKKNQPKDIKDIVDTRMYKERDDLNYTLIINK
                     DGNYSWRPLVLLHPILYVDLVNCLTKEDHWEELKKRFSEFKKDKNINCYSIPVEASKGS
                     KRTDLGETILNWWEYFEQKSLAQNIKYQYCMFTDIADCYPSIYTHSITWAMYGKEKVKN
                     DENKCSGSLGDKIDKKISGMQHNQTNGIPQGSVLMDFVAEIVLGYVDLRLSKELKKLEN
                     LKDYKVLRYRDDYRIFSNNRNDLEQIMKVLSEVLYDLNFKLNSSKTKLSDDIIIDSIKK
                     DKLYWEEIKASIRMNATNLDGDREIRYSINLQKHLLEIKKLADKHPNSGQLKKALSEFN
                     KERIIKITSKPNDLLPLIGILVDIMINNPGSLPQCVLIIGQLLNFENESKAREIVEMII
                     NKYALKPNTEFMMIWFQRLTTIFGEMFDSVLSSEFVSKIKDPVSNQMFSVDWLNEDAKK
                     SFYEGTIKDEEKYIKMSKKIYITEFDDFNDYPF"
                     /name="RNA-directed DNA polymerase"
     gene            32297..>33741
                     /locus_tag="I7089_RS15380"
                     /old_locus_tag="I7089_15380"
                     /pseudo=""
     CDS             32297..>33741
                     /locus_tag="I7089_RS15380"
                     /old_locus_tag="I7089_15380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305144.1"
                     /GO_function="GO:0015666 - restriction
                     endodeoxyribonuclease activity [Evidence IEA]; GO:0009007 -
                     site-specific DNA-methyltransferase (adenine-specific)
                     activity [Evidence IEA]"
                     /GO_process="GO:0006306 - DNA methylation [Evidence IEA];
                     GO:0009307 - DNA restriction-modification system [Evidence
                     IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit M"
                     /name="type I restriction-modification system subunit M"
     gene            complement(33797..34477)
                     /locus_tag="I7089_RS15385"
                     /old_locus_tag="I7089_15385"
     CDS             complement(33797..34477)
                     /locus_tag="I7089_RS15385"
                     /old_locus_tag="I7089_15385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(35012..35692)
                     /locus_tag="I7089_RS15390"
                     /old_locus_tag="I7089_15390"
     CDS             complement(35012..35692)
                     /locus_tag="I7089_RS15390"
                     /old_locus_tag="I7089_15390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_002287920.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIGADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            <35768..36334
                     /locus_tag="I7089_RS15395"
                     /old_locus_tag="I7089_15395"
                     /pseudo=""
     CDS             <35768..36334
                     /locus_tag="I7089_RS15395"
                     /old_locus_tag="I7089_15395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            complement(36381..36617)
                     /locus_tag="I7089_RS15875"
     CDS             complement(36381..36617)
                     /locus_tag="I7089_RS15875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_306297428.1"
                     /translation="MKQNTSIAKNTTKFKCTAAAWRISISPTNRTNNRGMILFIWISFF
                     LLGYRVLPAYFAPPKRRGRLERLVRNKNHSLSY"
                     /name="hypothetical protein"
     gene            36715..36894
                     /locus_tag="I7089_RS15400"
                     /old_locus_tag="I7089_15400"
     CDS             36715..36894
                     /locus_tag="I7089_RS15400"
                     /old_locus_tag="I7089_15400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001120991.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLLI
                     AQEKAGFEVPALKK"
                     /name="hypothetical protein"
     gene            37025..37294
                     /locus_tag="I7089_RS15405"
                     /old_locus_tag="I7089_15405"
     CDS             37025..37294
                     /locus_tag="I7089_RS15405"
                     /old_locus_tag="I7089_15405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /GO_component="GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="WP_000388479.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKRD
                     YDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
                     /name="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
     gene            37287..37544
                     /locus_tag="I7089_RS15410"
                     /old_locus_tag="I7089_15410"
     CDS             37287..37544
                     /locus_tag="I7089_RS15410"
                     /old_locus_tag="I7089_15410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /GO_process="GO:0008219 - cell death [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="WP_000588503.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLGK
                     PEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
                     /name="Txe/YoeB family addiction module toxin"
     gene            38003..39007
                     /locus_tag="I7089_RS15415"
                     /old_locus_tag="I7089_15415"
     CDS             38003..39007
                     /locus_tag="I7089_RS15415"
                     /old_locus_tag="I7089_15415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000455809.1"
                     /translation="MEYKFNLNLKEVLPTQGTININGQDNDDDIVIKKIEFIDSDINVF
                     FYSKEKLADFSNIAEMIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACEI
                     GVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRNKL
                     VHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNKSQITL
                     SKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD"
                     /name="hypothetical protein"
     gene            complement(39172..39786)
                     /locus_tag="I7089_RS15420"
                     /old_locus_tag="I7089_15420"
     CDS             complement(39172..39786)
                     /locus_tag="I7089_RS15420"
                     /old_locus_tag="I7089_15420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001261742.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRPV
                     FQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGNPL
                     LDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQRRL
                     VYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
                     /name="recombinase family protein"
     gene            40236..41561
                     /locus_tag="I7089_RS15425"
                     /old_locus_tag="I7089_15425"
     CDS             40236..41561
                     /locus_tag="I7089_RS15425"
                     /old_locus_tag="I7089_15425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="WP_000969590.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRAD
                     NTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNIFR
                     RYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIATVG
                     VGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRLNQMG
                     IMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQVLPRD
                     YTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKIPITDNT
                     KELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEENLDKIIDK
                     IRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
                     /name="Y-family DNA polymerase"
     gene            41554..41904
                     /locus_tag="I7089_RS15430"
                     /old_locus_tag="I7089_15430"
     CDS             41554..41904
                     /locus_tag="I7089_RS15430"
                     /old_locus_tag="I7089_15430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000568378.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTEE
                     IAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIRHI
                     EFYQDNKWSRLE"
                     /name="hypothetical protein"
     gene            41901..42080
                     /locus_tag="I7089_RS15435"
                     /old_locus_tag="I7089_15435"
     CDS             41901..42080
                     /locus_tag="I7089_RS15435"
                     /old_locus_tag="I7089_15435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001021554.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAAA
                     GYHNFRFYIFPLYI"
                     /name="hypothetical protein"
     gene            42216..42506
                     /locus_tag="I7089_RS15440"
                     /old_locus_tag="I7089_15440"
     CDS             42216..42506
                     /locus_tag="I7089_RS15440"
                     /old_locus_tag="I7089_15440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000026576.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITRQ
                     RRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
                     /name="hypothetical protein"
     gene            42874..43662
                     /locus_tag="I7089_RS15445"
                     /old_locus_tag="I7089_15445"
     CDS             42874..43662
                     /locus_tag="I7089_RS15445"
                     /old_locus_tag="I7089_15445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302898.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA]"
                     /GO_process="GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000101106.1"
                     /translation="MARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVDIDPQGN
                     ATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAEREFTQVGSE
                     HRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLKGLIKLSET
                     IETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKTYIRRTITVD
                     EAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
                     /name="AAA family ATPase"
     gene            43649..43975
                     /locus_tag="I7089_RS15450"
                     /old_locus_tag="I7089_15450"
     CDS             43649..43975
                     /locus_tag="I7089_RS15450"
                     /old_locus_tag="I7089_15450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000796719.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKDQ
                     GSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLAKK
                     QNKI"
                     /name="hypothetical protein"
     ARG             21959..22923
                     /name="vanH-A"
                     /gene="vanH-A"
                     /gene_name="D-lactate dehydrogenase VanH-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             19083..20233
                     /name="vanS-A"
                     /gene="vanS-A"
                     /gene_name="vancomycin resistance histidine kinase VanS-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             24993..25900
                     /name="vanY-A"
                     /gene="vanY-A"
                     /gene_name="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="99.67"
                     /coverage="100.0"
     ARG             23957..24561
                     /name="vanX-A"
                     /gene="vanX-A"
                     /gene_name="D-Ala-D-Ala dipeptidase VanX-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             21959..22926
                     /name="vanH gene in vanA cluster"
                     /gene="vanH gene in vanA cluster"
                     /gene_name="vanH; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             18410..19104
                     /name="vanR gene in vanA cluster"
                     /gene="vanR gene in vanA cluster"
                     /gene_name="glycopeptide resistance gene cluster; vanR"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             24993..25903
                     /name="vanY gene in vanA cluster"
                     /gene="vanY gene in vanA cluster"
                     /gene_name="vanY; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="99.67"
                     /coverage="100.0"
     ARG             26057..26541
                     /name="vanZ gene in vanA cluster"
                     /gene="vanZ gene in vanA cluster"
                     /gene_name="vanZ; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             19083..20237
                     /name="vanS gene in vanA cluster"
                     /gene="vanS gene in vanA cluster"
                     /gene_name="vanS; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="100.0"
                     /coverage="94.79"
     ARG             23957..24564
                     /name="vanX gene in vanA cluster"
                     /gene="vanX gene in vanA cluster"
                     /gene_name="vanX; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="99.5"
                     /coverage="100.0"
     ARG             2692..3428
                     /name="ErmB"
                     /gene="ErmB"
                     /gene_name="Erm 23S ribosomal RNA methyltransferase"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; lincosamide antibiotic;
                     streptogramin antibiotic; streptogramin A antibiotic;
                     streptogramin B antibiotic"
                     /identity="98.37"
                     /coverage="98.79"
     ARG             6688..7352
                     /name="ANT(6)-Ia"
                     /gene="ANT(6)-Ia"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="95.02"
                     /coverage="77.0"
     ARG             7593..8134
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="99.44"
                     /coverage="100.0"
     Typing          2..1041
                     /name="rep_cluster_889"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(16514..17391)
                     /name="rep_cluster_1093"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.351"
                     /coverage="99.0"
                     /evalue="0.0"
ORIGIN
        1 atgaatgatt ttaattatta caaatcaaaa gaaatttatc gtgaaaaata ttatcaaatg
       61 cctaaggtat tttttactaa cgaaaaatac atggatctat caaatgatgc aaaaattgct
      121 tatatgctac ttaaagatcg atttgattat tcagtcaaaa ataactgggt agattctgat
      181 gataatatat ttttcatatt cacagttgaa gaattaatga aattgttaca atgccgcgaa
      241 ggtaaagtat ctaaaatcaa aaaggaatta gaaaaagcag gtcttctgaa acagaagaga
      301 ggaagagtaa ataaacgtga cggtaagatt gaatccatgc ctaatttatt gtacttaggc
      361 aagccagaag taacgaatca agacgtcttt aaaatcatgg aagaggaaga caatactgat
      421 accaccgtaa ttgcgaaaat cgcaaatacg gcaaaaccgc gagaaatcaa tgataccacc
      481 gtaattgcga aaatcgcaaa tacggcaaaa tccagtcata tcaaggactc aaccgtaatt
      541 gcgaaaatcg cagacaatct attctattct aattctatag acactaatag acacataata
      601 gacactgaaa ctgatcagtt acaaaatcaa gttttactag ataacttcgt cgacatcatg
      661 aaagaggaca gtataaatac atttgtacca gaaaatgtat taaacttgat aaaaacattt
      721 tctagtactt acgaagacgc tcaaaaaacc gtccaaacta ttcataatgc aaagaaaaaa
      781 gctgaagaat tagagcaaac agttgttgtt tatgaagaac tggaatctta tggaattgat
      841 gctgacaaag gattatatat gactttgctg aaagcttatc aaaaacaaaa aactgaaaaa
      901 gtaaacaatt tgcagaatct aattttcgtt tatgtaaaaa attggtttgt cgaaaaagct
      961 attgcggcaa agcttgcaaa cgaacaaaga gaaacattta acgaattacc aacagttagt
     1021 acggaaaatt ggctagagta gttgataaaa agcgatcact ataaaaatga tcaattttaa
     1081 attagaactt ttttatgatt ttaattttat tacaaatgtt acaaataaat agctattatt
     1141 ccggagtttt tagattaaaa gtttatgaaa acaatcacaa acgtaggttt taaagtcata
     1201 atcgttagat attttagtta tttttcattc aaaaaaatag ggaactagtg tttgcatatg
     1261 tgcttttttg agttataata attcatgaag agaggtaatt cacttatttc cccaagctga
     1321 aaagcctgat attacttctt ttcaggcagt gctgctaata ttcaattaca cttttttgta
     1381 tatttttagt tgttttaaat ttaattgtct gatatgcttg tgatgaattg attttcgttc
     1441 tgcacttttg gacgataaat tgtgataatt gaaaatacaa aaaaaagaaa ggcccctgta
     1501 aggctcggga gactggtaat ctccgtcagt gtcctacagg aaagcattaa gatgacgcct
     1561 taatgcgtgc ccttcagtgt tacggtatta cccgcaacgg acggttctgt tgcaaagttt
     1621 taaataaaga ataaaatccc ttacggtatc tatgatttaa gctgggattc ccaataatac
     1681 cttgatttca gtacagaccg aaaacccgaa gagagtgcct tcttttcggg ttttcttata
     1741 taatcctcga atggcttcca tgcctttaat cgtggtagag gcagtgcgta aacttcgata
     1801 gaatttattg cgtctcttta ctggacgatg gtcttgttca atcaaattat tcaggtattt
     1861 aatggtacga tgttctgtcc cttgataaaa gccgtattct tttagtttct taaaggcact
     1921 tgtaatagag ggggctttat ctgtgactac aaccttcggt tcatcaaact gcttcactaa
     1981 ccgcttaaga aaagcatagg ctgcttgtgt gtcccgtttt ttacgtaacc aaatatccaa
     2041 ggttaaacca tctgcaccga tggctcgata caaataatgc cattttcctt taattttgat
     2101 gtacgtttca tccattttcc atgaataaaa ggatttttta tttttctttt tccaaatttg
     2161 atagagtagt ttgccatatt cttgcaccca acgataaatc gtcgtatgag aaacgttaat
     2221 gccacgatca tataagattt cttgaacttc acgatagcta aggttataac gaagatagta
     2281 gcccacggct acaataatca catcctgctg aaattgcttt cctttaaaat gattcatcgt
     2341 cattcctcct gctatctttt tctattattc taccttattt gatagtagat ttaaaacttt
     2401 gcaacagaac cattttgtgt ataataggaa ttgaagttaa attagatgct aaaaatttgt
     2461 aattaagaag gagggattcg tcatgttggt attccaaatg cgtaatgtag ataaaacatc
     2521 tactgttttg aaacagacta aaaacagtga ttacgcagat aaataaatac gttagattaa
     2581 ttcctaccag tgactaatct tatgactttt taaacagata actaaaatta caaacaaatc
     2641 gtttaacttc tgtatttatt tacagatgta ataacttcag gagtgattac atgaacaaaa
     2701 atataaaata ttctcaaaac tttttaacga gtgaaaaagt actcaaccaa ataataaaac
     2761 aattgaattt aaaagaaacc gataccgttt acgaaattgg aacaggtaaa gggcatttaa
     2821 cgacgaaact ggctaaaata agtaaacagg taacgtctat tgaattagac agtcatctat
     2881 tcaacttatc gtcagaaaaa ttaaaactga acattcgtgt cactttaatt caccaagata
     2941 ttctacagtt tcaattccct aacaaacaga ggtataaaat tgttgggagt attccttacc
     3001 atttaagcac acaaattatt aaaaaagtgg tttttgaaag ccatgcgtct gacatctatc
     3061 tgattgttga agaaggattc tacaagcgta ccttggatat tcaccgaaca ctagggttgc
     3121 tcttgcacac tcaagtctcg attcagcaat tgcttaagct gccagcggaa tgctttcatc
     3181 ctaaaccaaa agtaaacagt gtcttaataa aacttacccg ccataccaca gatgttccag
     3241 ataaatattg gaagctatat acgtactttg tttcaaaatg ggtcaatcga gaatatcgtc
     3301 aactgtttac taaaaatcag tttcatcaag caatgaaaca cgccaaagta aacaatttaa
     3361 gtaccgttac ttatgagcaa gtattgtcta tttttaatag ttatctatta tttaacggga
     3421 ggaaataatt ctatgagtcg cttttttaaa tttggaaagt tacacgttac taaagggaat
     3481 ggagataaat tattagatat actactgaca gcttccaaga agctaaagag gtccctagcg
     3541 cctacgggga atttgtatcg ataaggggta caaattccca ctaagcgctc gggacccctt
     3601 gtaggaaaat gtcctaagtg tggcaacaat attgtattaa aaaaatcgtt ttatggttgt
     3661 tcaaattatc ctgaatgtaa gtttacttta gctgaacatt ttagaaagaa aaaactaacc
     3721 aaaacgaatg taaaagaatt actggaggga aaagaaaccc tggtaaaagg aatcaaaaac
     3781 aaagagaaaa agccctacaa tgccgttgta aaaattgggg aaaagggata tattgatttt
     3841 atctcttttt caaaataaac atggggctga cccaaaagta gctcctatat gaaaaataga
     3901 ggtctttcca tttagatagt agtggaaaga cctctattta tcttttgaaa gtgaatacaa
     3961 aaataaagca cactctgcta taatataggt gattaatcca tttgagagag gtgctttatc
     4021 atgtatcaaa attataccat aaaccaactt tgtttgccta tagatcttga aattaaatta
     4081 gaagaaaatg attttgctca tgccattgtg cagtttgttg actctattcc cgatgaagtc
     4141 tttcttcctt attatcaatc tatgggtaga ccccaatatc atcctcgtat gctactttcc
     4201 attattcttt gtgcctatat tcaaggggtt tattcgggcc gccaaataca aaatatgctg
     4261 atagatagta ttcggatgcg ctacttatct caagagcaat tccctaactt tcgtactatt
     4321 aatcgttttc gcgttcatcc gattatgaac gatattctag atcattcatt tgttcaattt
     4381 cgtgagctac tggttcaaag tggcttaatc agtggcagtg ctctatacat tgatggtaca
     4441 aaaattgaag cggatgcgaa taaatactct ttcgtttgga aaaaaagtat tttaaagtat
     4501 aaggatagcc ttgatcaaaa agcccttgaa aactaccaac aaatggtgga aacaaaaatc
     4561 ttacctgagt taatagatga tttaaaggat gaactttcta tagaagagat tgaaaggatt
     4621 cgtcaatctt tggaagaaaa ggaaaatcaa ttaattgaag cgattgacca aaccgaaaca
     4681 gtagaagggg gctgacccat tattaataag gagtggacaa catgattgat gtaaatgagc
     4741 tattggaaga agctattaga gaaactgaaa atctaaatga tggcgaagtt tttcttgtta
     4801 aagatttatt caagggatat gtggggaata ggatacccag aaaggatcga cttctgcttg
     4861 gaacgttatt tttaaaccat gttagcaaaa tgaatggtaa tttaaaggct attgaaaaga
     4921 cttcatctaa tcagcagagg tataaaaaga caattgataa gttttaacta tcttttgtga
     4981 aattaaaaaa attataaata tgttgagtag aagcaaaaga tttggcttgg aatttttaca
     5041 gcagtgaatc gataaaagga gcatgcttga tggtagataa tattattaaa tcagtagcag
     5101 agaaattatc ctctctgtct tatatagaag gtattgtttt aggtggttca cgtgcaaggg
     5161 gcacccatac agaggattcg gatatagata tcggcatcta ttacaattca gaatcatttg
     5221 acataaatac tattaatcaa ttcgctacaa agctggatga tgagcataga aataaccttg
     5281 ttgtacctcc cggagcatgg ggtgattgga ttaatggcgg cggatggtta gtcataaacg
     5341 ggtatcatgt ggatttaatt ttacgtgata ttaaacgtgt ggaacaaata atgaaagata
     5401 cagagcacgg aattgttact gccaattatc agactgggca tccccatggt tatattagtg
     5461 caatgtatcg aggagaatta gcgattagca aaatactata tgctaagaat gaaagcttat
     5521 gcgaattaaa aaaacaggca gaaacttatc ccaatgcttt gcagaaaagt ttagttaact
     5581 tttttatgtt tgaagcaggg ttctctttaa tgtttgtaaa agcaaattcg ggaacagacg
     5641 ataaatatta tattgcgggt catgtttttc gtatagtttc atgtttaaat caagtgttat
     5701 ttgcatgtaa taatgcttat tgtatcaacg aaaagaaagc tataaaactg cttgaaactt
     5761 ttgaacataa acctgaaaaa tataccgaga aggtaaatca tatttttgaa gtactcggta
     5821 tctcactttt tgaatgctac gacatgaccg agaagcttta taatgaagtg aatgaaattg
     5881 tatcggagat aaataacttt ttaaacgagg agagttcaga tgaaagaaaa caaatatgat
     5941 gataatatat tttttcaaaa atacagtcaa atgagtcgct cgcagaaagg actggctggt
     6001 gcgggagaat gggagacttt gaaaaagatg ctacctgatt ttaagggtaa gcgtgtgctt
     6061 gatttaggat gcggctatgg atggcactgt atatatgcga tggaaaacgg tgcttcctct
     6121 gtagtaggtg ttgatatttc tcataaaatg ctcgaagtag caaaaggaaa aacccatttt
     6181 ccacagattg aatatgaatg ctgtgccata gaagatgtgg atttcccaga ggagagcttt
     6241 gatgtaatac taagttcgct tgcgtttcat tatgtagcag actatgagaa tttaataaaa
     6301 aagatatata ggatgctgaa ggctggtggc aatttagttt ttacagttga acatcctgtt
     6361 tttactgctc atggaacaca agactggtat tataacgaaa aaggagaaat actgcatttc
     6421 ccggtggaca attattatta tgagggcaaa cggacagcta tgtttttgga agaaaaggtt
     6481 acaaaatatc atagaacact gaccacatat ctaaatacac tgctttcaaa tagttttata
     6541 ataaatcaga ttgtggagcc acagccgcca gagaacatga tggatattcc ggggatggcg
     6601 gatgaaatgc gacgcccaat gatgctgatt gtatcggcaa aaaagaagat gtaataatat
     6661 agaaaaaata aacgaggagt atgtaaatga gatcagaaaa agaaatgatg gatttagtac
     6721 tttctttagc agaacaggat gaacgtattc gaattgtgac ccttgagggg tcacgcgcaa
     6781 atattaatat acctaaagat gaatttcagg attatgatat tacatatttt gtaagtgata
     6841 tagaaccgtt tatatctaat gatgactggc ttaatcaatt tgggaatata ataatgatgc
     6901 aaaagccgga ggatatggaa ttattcccac ctgaagaaaa gggattttcc tatcttatgc
     6961 tatttgatga ttacaataaa attgatctta ccttattgcc cttggaagag ttagataatt
     7021 acctaaaggg cgataaatta ataaaggttc taattgataa agattgtaga attaaaaggg
     7081 acatagttcc gactgatata gattatcatg taagaaagcc aagcgcaagg gagtatgatg
     7141 attgctgcaa tgaattttgg aatgtaacac cttatgttat taaaggattg tgccgtaagg
     7201 aaattttatt tgctattgat cattttaatc agattgttcg ccatgagctg ctgagaatga
     7261 tatcatggaa ggtcggcatc gaaacaggct ttaaattaag tgtaggcaag aactataagt
     7321 ttattgaaag gtatatatcc gaggatttgt gagagaaact tttgtccacc taccggatgg
     7381 attcctatga aaacatatgg gaagcattat ttctatgcca tcaattgttc agggcggtat
     7441 ccggtgaggt ggcggaaagg cttcattatg cctatccgga gtatgatagg aatataacaa
     7501 aatataccag ggacatgtat aaaaaataca ctggtaaaac cggctgcctg gatagcacat
     7561 atgccgctga tatagaagag aggcgggaac agtgattaca gaaatgaaag cagggcacct
     7621 gaaagatatc gataaaccca gcgaaccatt tgaggtgata ggtaagatta taccgaggta
     7681 tgaaaacgag aattggacct ttacagaatt actctatgaa gcgccatatt taaaaagcta
     7741 ccaagacgaa gaggatgaag aggatgagga ggcagattgc cttgaatata ttgacaatac
     7801 tgataagata atatatcttt actaccaaga cgataaatgc gtcggaaaag ttaaactgcg
     7861 aaaaaattgg aaccggtacg cttatataga agatatcgcc gtatgtaagg atttcagggg
     7921 gcaaggcata ggcagcgcgc ttatcaatat atctatagaa tgggcaaagc ataaaaactt
     7981 gcatggacta atgcttgaaa cccaggacaa taaccttata gcttgtaaat tctatcataa
     8041 ttgtggtttc aaaatcggct ccgtcgatac tatgttatac gccaactttg aaaacaactt
     8101 tgaaaaagct gttttctggt atttaaggtt ttagaatgca aggaacagtg aattggagtt
     8161 cgtcttgtta taattagctt cttggggtat ctttaaatac tgtagaaaag aggaaggaaa
     8221 taataaatgg ctaaaatgag aatatcaccg gaattgaaaa aactgatcga aaaataccgc
     8281 tgcgtaaaag atacggaagg aatgtctcct gctaaggtat ataagctggt gggagaaaat
     8341 gaaaacctat atttaaaaat gacggacagc cggtataaag ggaccaccta tgatgtggaa
     8401 cgggaaaagg acatgatgct atggctggaa ggaaagctgc ctgttccaaa ggtcctgcac
     8461 tttgaacggc atgatggctg gagcaatctg ctcatgagtg aggccgatgg cgtcctttgc
     8521 tcggaagagt atgaagatga acaaagccct gaaaagatta tcgagctgta tgcggagtgc
     8581 atcaggctct ttcactccat cgacatatcg gattgtccct atacgaatag cttagacagc
     8641 cgattagccg aattggatta cttactgaat aacgatctgg ccgatgtgga ttgcgaaaac
     8701 tgggaagaag acactccatt taaagatccg cgcgagctgt atgatttttt aaagacggaa
     8761 aagcccgaag aggaacttgt cttttcccac ggcgacctgg gagacagcaa catctttgtg
     8821 aaagatggca aagtaagtgg ctttattgat cttgggagaa gcggcagggc ggacaagtgg
     8881 tatgacattg ccttctgcgt ccggtcgatc agggaggata tcggggaaga acagtatgtc
     8941 gagctatttt ttgacttact ggggatcaag cctgattggg agaaaataaa atattatatt
     9001 ttactggatg aattgtttta gtacctagat ttagatgtct aaaaagcttt aactacaagc
     9061 tttttagaca tctaatcttt tctggctctt tgtcaaatga tgttggtaaa gagaaatctt
     9121 agaataattg gagatcaagt ggatcagttc ctcttgatct tttttagttg aaaatcaatg
     9181 cgttgccatg acgaatcatg atgcgcaatt tgaaattata aaagctacga aagccatatg
     9241 catttcgttt taacactttg atatggttgt tcagacattc aagtgggcca tttgaataac
     9301 tttgttgtaa agcatttttg atttgtggca gaaatttctg gaacgttctc aaggtcgtct
     9361 gatagccttc gggaagcatg atattattgg taagtagttc ttcaaacgat acgtagtctc
     9421 gttcctttac agcgtaaaga aagtcttgat ataactgata gcctacacgc aaagcagggc
     9481 tccctttcag taagcgatcc acaatatcgg tctctgttaa atgagctttg aagccaggtc
     9541 gccaaaggcg tcgagtataa tcaagcttgc gttcatcttt ttgaagaagt ttccagtatc
     9601 tttttaattg cttacctaat tgatagtgtt tttgttcttt gctttttaat agttggttcg
     9661 tttctttgat tcgatgattg cgaaaggtac gaccaatatg ttggacgatg tgaaaccggt
     9721 caataatcag ctgtgctttt ggaaacagct ttttaacgag cgatacataa ggagcgtaca
     9781 tatcaatcac gatccattcg accgcttcac gaatttctcg tgaaaaatga ctaaaataac
     9841 gttttaaaaa aggcagttgt cggttctcga caatgtccaa taagcgctgt gtttgtccat
     9901 ccatcatgat gaaactcata gcacctgaaa caccccgaac tgatttgaat tcatcaaaac
     9961 aaagtacctt aggtaacggt gtccgaaaag gattcaacgg acgataaaat cgcttcataa
    10021 tacggtaaac agaagagacc gatagatttt tctgagcggc gatctctgtc attgaggtat
    10081 tttttttcag acgagtcacg acagaccagc ggactttctc actgatgaaa caatgttttt
    10141 tcgcaacaga agtatctgcg acaaaggtcc gctgacaagc tttgcatttg aagcgttgct
    10201 ttttcaattc gaggtaggta cggtattcag aaacatcgtt cattaacaac cggacggttg
    10261 ttgtacccca acgcacaata tctgaagcaa tctggtgttt acagtggatg cattcttggg
    10321 ctgtataaat caagtttcca cgataaatat gacagatttg ccctttgtat ttttcttttg
    10381 tgagacaatt ttcgttaaaa gtaactgata agtctagaat atctaatgtt tctttgataa
    10441 ggtgagtgta agacatcttg attcctcctt ttgggttggt tcgccaaatt aattctaaag
    10501 gatttcaagg tgtcttttct atatgttttg gaaaataaaa aagatgctgg tgtcatccac
    10561 caacatcaaa aagtatagag cctcttttct gaagtacatc cgcaactgtc catactctga
    10621 tgttttatat cttttctaaa agttcgctag atagagttct atattagaga tgtaaagagt
    10681 tttggtgaag aggtttgtga gtatggcttt tataaccagg gtgcaatgag aagcactaac
    10741 agcagctagc ttaagaacgc ataggatata ctttttatgg aagtcacaga ggaggaataa
    10801 aatttgaaca ggattaacag agtaacctct attcttattc agctgcaatc aaaaaaaata
    10861 attcctgcca aagaaattgc acagcgattt aatataagct taaggacagt ttacagagat
    10921 atccggacac ttgaagaagc cggaatacca attggatctg aggccggaaa aggatatttt
    10981 cttgtagagg gcttcctact tccgccggta atgtttacag cggcggaagt gggtgcattg
    11041 attacagcag ggaaattttt aaattgccat ggagatgaat catttataaa ggattttgat
    11101 tcagctatgt ataaaatcaa atctattttg aagcatggtg aaaaaaacta tgcacaggag
    11161 ttggagaaca gtattaacgt gtacagcaca tctggacaga aaaatacatt ggcggataac
    11221 gttattgcag caattcagac tgcaatctgc aataaaaggg taatatcaat tcaatatcct
    11281 gcatcaggag ggcaagaacc ggaaagcaga atgatagagc cggttctgtt gcaaagtttt
    11341 aaataaagaa taaaatccct tacggtatct atgatttaag ctgggattcc caataatacc
    11401 ttgatttcag tacagaccga aaacccgaag agagtgcctt cttttcgggt tttcttatat
    11461 aatcctcgaa tggcttccat gcctttaatc gtggtagagg cagtgcgtaa acttcgatag
    11521 aatttattgc gtctctttac tggacgatgg tcttgttcaa tcaaattatt caggtattta
    11581 atggtacgat gttctgtccc ttgataaaag ccgtattctt ttagtttctt aaaggcactt
    11641 gtaatagagg gggctttatc tgtgactaca accttcggtt catcaaactg cttcactaac
    11701 cgcttaagaa aagcataggc tgcttgtgtg tcccgttttt tacgtaacca aatatccaag
    11761 gttaaaccat ctgcatcgat ggctcgatac aaataatgcc attttccttt aattttgatg
    11821 tacgtttcat ccattttcca tgaataaaag gattttttat ttttcttttt ccaaatttga
    11881 tagagtagtt tgccatattc ttgcacccaa cgataaatcg tcgtatgaga aacgttaatg
    11941 ccacgatcat ataagatttc ttgaacttca cgatagctaa ggttataacg aagatagtag
    12001 cccacggcta caataatcac atcctgctga aattgctttc ctttaaaatg attcatcgtc
    12061 attcctcctg ctatcttttt ctattattct accttatttg atagtagatt taaaactttg
    12121 caacagaacc ctatagagaa gaataaattc atttctactg acgtaaattt gcgtaaagga
    12181 atcgtattta attcatggtg gtatttcaca atttcatttg ccataaaatc ctccttcaag
    12241 attaactact taacaaaatt ataaagagct ttctaatagg ggtcaagccc ctaattaaag
    12301 acccctaaaa acagacaaaa agacccccaa aaacagacaa aaagacccct aaaaacagac
    12361 aaaaagaccc ctaaaaacag acaaaaagac ccccaaaaga ttctgcacac cttgggagag
    12421 taagcataca gccgacggta aagaggttta aaaagaggtt taaaaagaga ttataaaaga
    12481 ggagaggggc aaaatttccc gcctaaaaat tttctgcttt tttagccaaa caggttcgcg
    12541 aattttacta aactgggaaa cttgctccct ctggtcgcta aaaaggtgtg agggaaaaac
    12601 accctcacat tgtactgcgc agtcgcctaa aggctccttt gctaaaaacg ttgtttaaag
    12661 agattttttt agaggctctg cgcgctcgtt taagccgttt taagacagtt tagtatggat
    12721 aacccttatc ttgttcttaa agcaccttac aggcggtcag ggcaagccct aacaaccctt
    12781 aaagagcata aaaccatcct aaaattcgat ttaatctgtc ttatctatgt tcttgtatat
    12841 tttatatacc ttgggtagta aaacgtctga aaacgcaaat aagagcgtat gaaacaaaac
    12901 aataagcaac cgattcagca gaattccgga ggagccattt tcgtacgtta gcaaaaaagt
    12961 gctgttgcta aaagctgctt gcggtgcgga gcgaacaagg tctcctagag cgagacgtgt
    13021 acaaacaagc ttacaaattc gtgaaaggca ccggttttgc gccatttcca agcaaaaaaa
    13081 ggtctatcga gcaagctcga tagaccgatc gcatttagcc ccccgcattc taacaggggg
    13141 ggaataatgt gaaaaattat ggtagtaatg cttgatatat aggcatttct tttggttgca
    13201 cacttaaaaa aaatcacgat tttgacaact aaatttttaa ataaaaaagc tttacagttt
    13261 aattcaaatg tgttttaata tatctatcag tacttgccac gcctctgatt taatatcatg
    13321 cgcattatgg tagggctttt tttttatatt tttttaagaa agaagattct tatgaagaca
    13381 tcaaatagaa aatataaagt taaaacagtt aatcatagaa ttccacctaa aaaggcatta
    13441 tgtgtaatta ataattccaa agtaattaat caagagttaa aaccatattt atccgagcaa
    13501 gaaatgataa aaaaaataag taaagatatt tttttaacaa attccgatac aattttatta
    13561 gaaaagtttt taaagaaaaa tagttatttt cgatttagta tttatgttaa attaatgaaa
    13621 aatatagata aagttactat tctagatgtt attgaaacgt acaaattaga ttcattcatt
    13681 cgtaatcaat tgcattattt tgtgaatcaa atagaaattt tttggaaaaa atctctttca
    13741 gataatatgt gcgtttctta tgaagaaact agcatatttc cgaagaatca gtgttatttg
    13801 gataaaaata tttattcaga tttgaaatgg gctgaagata taattggtca ttttaatagt
    13861 tttttttatt caaatcaaag tcccactttt aaacatcatc atataaaaaa aaatcattgt
    13921 ttaccaatat gggctttatt tgaagaaata acatttggta gtttaacaac atttattaat
    13981 caacttaata cagagtatta taataattgg gtcatgagct gttatgataa tcctaaatac
    14041 aaaaaagcta tacgaagttg ggcaaacgta attagagctt atagaaataa gatagctcat
    14101 cattcaagaa tatatgcatt taaagttact gacgctccaa caatcataaa aaatgattcc
    14161 aaaagttatt ttcctgaaaa taacttaaaa gaaacccaaa agttatattt gtatggagga
    14221 ttatacgtta taaaacatct gttaatatat gaagatagca tgacacaaac tttatggaat
    14281 aaatttctaa tagatttaga aaaaaagatc gataaaatcc cttccttaga aaaatccaat
    14341 tatggttttc cggaaaattg gagaaacaag ttaaaaataa tgattgttta attgttattt
    14401 aaattgttag tagacataat gtacatacta ccaagtagcc cctggatcaa ccgatccagg
    14461 ggaagacttt gtgattttca attggtctat ctaaaacatc tttttaaaag cttgattctt
    14521 cgctgttggc ttttttcgat tctttgtgaa tattcagtga ttattttttt actacttgtt
    14581 attttccgag ggatttgtta aaagtttaat agcgtttctc agtaagggac gtcgtttttt
    14641 cattttccta tgtatggact gctcgaacga gcagcctttt tttattccag ggaacgtcct
    14701 attctttgag tttccatgct attgaataac cgggacttag ggattagggc agcgccccaa
    14761 aatgaaaaaa gaaaaatccg cttctgcgaa ttcttctttt ttttcgcaag ttggtaccaa
    14821 cttgcaaatc ttgctggaag accgatccct aaaaagaaat cgaggaattt ttttgttttt
    14881 cggtttcttt ttttatcttt ttagaaagtt tgttgggtca aaatttccag aagtaaaggt
    14941 ttgattggtt tctttttgac gatttttggg ttgatttcgt cgggaaggat tgagttgatt
    15001 ttcaattttt tctttcactt cttgatatac tttagaattt gtaccgataa gaacaccagt
    15061 atcttttaga tataaatcag caaattctgc catgatttct gtcatgatag aaatttcttt
    15121 tcccatggca ttgagttttg cttggttact ggttgtggtt gtattggtat caggttcata
    15181 actcatacat aaaaagcgaa tggcttctga ataattgtta acgtctggat ttttttcgat
    15241 gatggaatct aaaacgtcaa cgtgactggg ataaagggtt acgtgttttt gaacagaagt
    15301 ttttctcatg ttatattcct ccgataagtg tttcaatgag ttggttgttt gtgtgaacat
    15361 agtcatttag tatgttcgta ttttctgctt gaatggcaat aaatttttcg aataataaat
    15421 cgaattgatc ttttttgtaa ttcataagtt cgtggtcaaa atcgttttcg attaaaattt
    15481 ttaggtattg atttcgactc cattttttgc ccgttttggt tgttagttcc tgacaacgtt
    15541 tatctattct tgtaataatt ttgggattga tatttcgaac taaaatgtcc atggaaattt
    15601 tcctttcgta tcagtgtata atttatgtat atcatacaaa tatagtattt gtatagctat
    15661 ttttcgccaa aacactatac atagcctagc cacaatggca aaaaagtgat agcaaatttt
    15721 tttctgagaa acgtgatagg cacagcttat ctagcacctt tcgtaagaaa gtgataccac
    15781 gtttccttat gctctttcaa aattcagaaa aatcagctgt aaaacgagtg cagtccgagt
    15841 aagattcaac gaaaaaacgg ggattggggc gccaccaaaa tatcgcaaca tgggcccatg
    15901 ttgctctgct cgcaaaagaa aaaagaagaa taaaaccagc aatttttatt aatttaaatt
    15961 gctggtttta ttgccagaat tgccaccatt ttttctccgt ctttgattgt ttttctatcg
    16021 attctgtttc ttcagaaaga gtcgttgatt tattttccga agattcttcc gtataagtca
    16081 actgtagttg ttcctgcagt ttctcgattt gttggttggc ttgcagggtg agttgttgtt
    16141 gttggtcgag taatttttgc atttgtttta tttgctcgtc tttttcttgt agttgcatat
    16201 ctttttgatt taactgttgt tctaggagag aaaggacttc taattcggga acttggttgg
    16261 cgtttttgtg gttttcggtt ttagtttttt cgccaactag ttgttgattt gagttttcgt
    16321 tttcgttaaa aaacattgat tttatagcct tttgtccggt ttcattaatc acaaacttgt
    16381 ttccgatttt cgaaaaccaa agttttcgat tttcgtcaga aacttttttg ttaattgctg
    16441 ttttactaac tcctaattct tcagcaagtt ctttgattgt tttttctgtc ataaaatcta
    16501 aaaacccctc aatctttgaa taagttttga agattgtcta ataagtcttt ttttagttct
    16561 gaaggaatat cggaatttat ctctgatttt tgtgcattat tttctttatt ttgggtattt
    16621 tgttctcttt ctaacttttc taactgttgt aaaagttcca attttcgctt ttgttctttg
    16681 attttttctt gtaatgaagt aggtgctttt tcagattgaa cttgttggtt agctagttct
    16741 aatgctttgt tttgttcttc ttttgttggg gcatgtttgt taaagtcgtc tgattttttt
    16801 atctcaggtt taaatgtaaa ttgatagcca atgacaggct ttccccgtcc ttttccgtat
    16861 ctcttttgga ttgtcagacc tttgaagatt gcggttagtt cttggcgaat aggctttata
    16921 atttttttat ttatatcact ttctctataa cttttaggga tatcaagtaa ttcatgaaag
    16981 tcttcttttg aaaaataggc aattcctttg gttctgtatt gttttaataa tctaaacatg
    17041 gttttggaat aactgctttc taattcattg aattgttgga gagaatatcg aacccattct
    17101 tcaagattat taagtaaggg taaggctttc tcatggactt gtatttcagc aaaaggaata
    17161 tcagcttttc catcgatttt aaattgatta aataaaacaa atcgttcacg ttgcaaaccg
    17221 tcagcacttc ttctaccaaa acgtaaatcc attaatttgt catacgttgt ttctaaatca
    17281 tctatgaatc gaacatttgc agttgcttta taattgctta aatcttttaa ttgttcgaat
    17341 gtaaattgta cttttttatc gcctacgtca cgcattctag atactataga gggttctgtt
    17401 gcaaagtttt aaataaagaa taaaatccct tacggtatct atgatttaag ctgggattcc
    17461 caataatacc ttgatttcag tacagaccga aaacccgaag agagtgcctt cttttcgggt
    17521 tttcttatat aatcctcgaa tggcttccat gcctttaatc gtggtagagg cagtgcgtaa
    17581 acttcgatag aatttattgc gtctctttac tggacgatgg tcttgttcaa tcaaattatt
    17641 caggtattta atggtacgat gttctgtccc ttgataaaag ccgtattctt ttagtttctt
    17701 aaaggcactt gtaatagagg gggctttatc tgtgactaca accttcggtt catcaaactg
    17761 cttcactaac cgcttaagaa aagcataggc tgcttgtgtg tcccgttttt tacgtaacca
    17821 aatatccaag gttaaaccat ctgcatcgat ggctcgatac aaataatgcc attttccttt
    17881 aattttgatg tacgtttcat ccattttcca tgaataaaag gattttttat ttttcttttt
    17941 ccaaatttga tagagtagtt tgccatattc ttgcacccaa cgataaatcg tcgtatgaga
    18001 aacgttaatg ccacgatcat ataagatttc ttgaacttca cgatagctaa ggttataacg
    18061 aagatagtag cccacggcta caataatcac atcctgctga aattgctttc ctttaaaatg
    18121 attcatcgtc attcctcctg ctatcttttt ctattattct accttatttg atagtagatt
    18181 taaaactttg caacagaacc ctgtattccg ctaatgggca atatttttaa agaagaaaag
    18241 gaaactataa aatattaaca gcctcctagc gatgccgaaa agccctttga taaaaaaaga
    18301 atcatcatct taagaaattc ttagtcattt attatgtaaa tgcttataaa ttcggcccta
    18361 taatctgata aattattaag ggcaaactta tgtgaaaggg tgataactat gagcgataaa
    18421 atacttattg tggatgatga acatgaaatt gccgatttgg ttgaattata cttaaaaaac
    18481 gagaattata cggttttcaa atactatacc gccaaagaag cattggaatg tatagacaag
    18541 tctgagattg accttgccat attggacatc atgcttcccg gcacaagcgg ccttactatc
    18601 tgtcaaaaaa taagggacaa gcacacctat ccgattatca tgctgaccgg gaaagataca
    18661 gaggtagata aaattacagg gttaacaatc ggcgcggatg attatataac gaagcccttt
    18721 cgcccactgg agttaattgc tcgggtaaag gcccagttgc gccgatacaa aaaattcagt
    18781 ggagtaaagg agcagaacga aaatgttatc gtccactccg gccttgtcat taatgttaac
    18841 acccatgagt gttatctgaa cgagaagcag ttatccctta ctcccaccga gttttcaata
    18901 ctgcgaatcc tctgtgaaaa caaggggaat gtggttagct ccgagctgct atttcatgag
    18961 atatggggcg acgaatattt cagcaagagc aacaacacca tcaccgtgca tatccggcat
    19021 ttgcgcgaaa aaatgaacga caccattgat aatccgaaat atataaaaac ggtatggggg
    19081 gttggttata aaattgaaaa ataaaaaaaa cgactattcc aaactagaac gaaaacttta
    19141 catgtatatc gttgcaattg ttgtggtagc aattgtattc gtgttgtata ttcgttcaat
    19201 gatccgaggg aaacttgggg attggatctt aagtattttg gaaaacaaat atgacttaaa
    19261 tcacctggac gcgatgaaat tatatcaata ttccatacgg aacaatatag atatctttat
    19321 ttatgtggcg attgtcatta gtattcttat tctatgtcgc gtcatgcttt caaaattcgc
    19381 aaaatacttt gacgagataa ataccggcat tgatgtactt attcagaacg aagataaaca
    19441 aattgagctt tctgcggaaa tggatgttat ggaacaaaag ctcaacacat taaaacggac
    19501 tctggaaaag cgagagcagg atgcaaagct ggccgaacaa agaaaaaatg acgttgttat
    19561 gtacttggcg cacgatatta aaacgcccct tacatccatt atcggttatt tgagcctgct
    19621 tgacgaggct ccagacatgc cggtagatca aaaggcaaag tatgtgcata tcacgttgga
    19681 caaagcgtat cgactcgaac agctaatcga cgagtttttt gagattacac ggtataacct
    19741 acaaacgata acgctaacaa aaacgcacat agacctatac tatatgctgg tgcagatgac
    19801 cgatgaattt tatcctcagc tttccgcaca tggaaaacag gcggttattc acgcccccga
    19861 ggatctgacc gtgtccggcg accctgataa actcgcgaga gtctttaaca acattttgaa
    19921 aaacgccgct gcatacagtg aggataacag catcattgac attaccgcgg gcctctccgg
    19981 ggatgtggtg tcaatcgaat tcaagaacac tggaagcatc ccaaaagata agctagctgc
    20041 catatttgaa aagttctata ggctggacaa tgctcgttct tccgatacgg gtggcgcggg
    20101 acttggattg gcgattgcaa aagaaattat tgttcagcat ggagggcaga tttacgcgga
    20161 aagcaatgat aactatacga cgtttagggt agagcttcca gcgatgccag acttggttga
    20221 taaaaggagg tcctaagaga tgtatataat tttggctctt tgtcaaatga tgttggtaaa
    20281 gagaaatctt agaataattg gagatcaagt ggatcagttc ctcttgatct tttttagttg
    20341 aaaatcaatg cgttgccatg acgaatcatg atgcgcaatt tgaaattata aaagctacga
    20401 aagccatatg catttcgttt taacactttg atatggttgt tcagacattc aagtgggcca
    20461 tttgaataac tttgttgtaa agcatttttg atttgtggca gaaatttctg gaacgttctc
    20521 aaggtcgtct gatagccttc gggaagcatg atattattgg taagtagttc ttcaaacgat
    20581 acgtagtctc gttcctttac agcgtaaaga aagtcttgat ataactgata gcctacacgc
    20641 aaagcagggc tccctttcag taagcgatcc acaatatcgg tctctgttaa atgagctttg
    20701 aagccaggtc gccaaaggcg tcgagtataa tcaagcttgc gttcatcttt ttgaagaagt
    20761 ttccagtatc tttttaattg cttacctaat tgatagtgtt tttgttcttt gctttttaat
    20821 agttggttcg tttctttgat tcgatgattg cgaaaggtac gaccaatatg ttggacgatg
    20881 tgaaaccggt caataatcag ctgtgctttt ggaaacagct ttttaacgag cgatacataa
    20941 ggagcgtaca tatcaatcac gatccattcg accgcttcac gaatttctcg tgaaaaatga
    21001 ctaaaataac gttttaaaaa aggcagttgt cggttctcga caatgtccaa taagcgctgt
    21061 gtttgtccat ccatcatgat gaaactcata gcacctgaaa caccccgaac tgatttgaat
    21121 tcatcaaaac aaagtacctt aggtaacggt gtccgaaaag gattcaacgg acgataaaat
    21181 cgcttcataa tacggtaaac agaagagacc gatagatttt tctgagcggc gatctctgtc
    21241 attgaggtat tttttttcag acgagtcacg acagaccagc ggactttctc actgatgaaa
    21301 caatgttttt tcgcaacaga agtatctgcg acaaaggtcc gctgacaagc tttgcatttg
    21361 aagcgttgct ttttcaattc gaggtaggta cggtattcag aaacatcgtt cattaacaac
    21421 cggacggttg ttgtacccca acgcacaata tctgaagcaa tctggtgttt acagtggatg
    21481 cattcttggg ctgtataaat caagtttcca cgataaatat gacagatttg ccctttgtat
    21541 ttttcttttg tgagacaatt ttcgttaaaa gtaactgata agtctagaat atctaatgtt
    21601 tctttgataa ggtgagtgta agacatcttg attcctcctt ttgggttggt tcgccaaatt
    21661 aattctaaag gatttcaagg tgtcttttct atatgttttg gaaaataaaa aagatgctgg
    21721 tgtcatccac caacatcaaa aagtatagag ccataatttt ttaggaaaat ctcaaggtta
    21781 tctttacttt ttcttaggaa attaacaatt taatattaag aaacggctcg ttcttacacg
    21841 gtagacttaa taccgtaaga acgagccgtt ttcgttcttc agagaaagat ttgacaagat
    21901 taccattggc atccccgttt tatttggtgc ctttcacaga aagggttggt cttaattatg
    21961 aataacatcg gcattactgt ttatggatgt gagcaggatg aggcagatgc attccatgct
    22021 ctttcgcctc gctttggcgt tatggcaacg ataattaacg ccaacgtgtc ggaatccaac
    22081 gccaaatccg cgcctttcaa tcaatgtatc agtgtgggac ataaatcaga gatttccgcc
    22141 tctattcttc ttgcgctgaa gagagccggt gtgaaatata tttctacccg aagcatcggc
    22201 tgcaatcata tagatacaac tgctgctaag agaatgggca tcactgtcga caatgtggcg
    22261 tactcgccgg atagcgttgc cgattatact atgatgctaa ttcttatggc agtacgcaac
    22321 gtaaaatcga ttgtgcgctc tgtggaaaaa catgatttca ggttggacag cgaccgtggc
    22381 aaggtactca gcgacatgac agttggtgtg gtgggaacgg gccagatagg caaagcggtt
    22441 attgagcggc tgcgaggatt tggatgtaaa gtgttggctt atagtcgcag ccgaagtata
    22501 gaggtaaact atgtaccgtt tgatgagttg ctgcaaaata gcgatatcgt tacgcttcat
    22561 gtgccgctca atacggatac gcactatatt atcagccacg aacaaataca gagaatgaag
    22621 caaggagcat ttcttatcaa tactgggcgc ggtccacttg tagataccta tgagttggtt
    22681 aaagcattag aaaacgggaa actgggcggt gccgcattgg atgtattgga aggagaggaa
    22741 gagtttttct actctgattg cacccaaaaa ccaattgata atcaattttt acttaaactt
    22801 caaagaatgc ctaacgtgat aatcacaccg catacggcct attataccga gcaagcgttg
    22861 cgtgataccg ttgaaaaaac cattaaaaac tgtttggatt ttgaaaggag acaggagcat
    22921 gaatagaata aaagttgcaa tactgtttgg gggttgctca gaggagcatg acgtatcggt
    22981 aaaatctgca atagagatag ccgctaacat taataaagaa aaatacgagc cgttatacat
    23041 tggaattacg aaatctggtg tatggaaaat gtgcgaaaaa ccttgcgcgg aatgggaaaa
    23101 cgacaattgc tattcagctg tactctcgcc ggataaaaaa atgcacggat tacttgttaa
    23161 aaagaaccat gaatatgaaa tcaaccatgt tgatgtagca ttttcagctt tgcatggcaa
    23221 gtcaggtgaa gatggatcca tacaaggtct gtttgaattg tccggtatcc cttttgtagg
    23281 ctgcgatatt caaagctcag caatttgtat ggacaaatcg ttgacataca tcgttgcgaa
    23341 aaatgctggg atagctactc ccgccttttg ggttattaat aaagatgata ggccggtggc
    23401 agctacgttt acctatcctg tttttgttaa gccggcgcgt tcaggctcat ccttcggtgt
    23461 gaaaaaagtc aatagcgcgg acgaattgga ctacgcaatt gaatcggcaa gacaatatga
    23521 cagcaaaatc ttaattgagc aggctgtttc gggctgtgag gtcggttgtg cggtattggg
    23581 aaacagtgcc gcgttagctg ttggcgaggt ggaccaaatc aggctgcagt acggaatctt
    23641 tcgtattcat caggaagtcg agccggaaaa aggctctgaa aacgcagtta taaccgttcc
    23701 cgcagacctt tcagcagagg agcgaggacg gatacaggaa acggcaaaaa aaatatataa
    23761 agcgctcggc tgtagaggtc tagcccgtgt ggatatgttt ttacaagata acggccgcat
    23821 tgtactgaac gaagtcaata ctctgcccgg tttcacgtca tacagtcgtt atccccgtat
    23881 gatggccgct gcaggtattg cacttcccga actgattgac cgcttgatcg tattagcgtt
    23941 aaaggggtga taagcatgga aataggattt acttttttag atgaaatagt acacggtgtt
    24001 cgttgggacg ctaaatatgc cacttgggat aatttcaccg gaaaaccggt tgacggttat
    24061 gaagtaaatc gcattgtagg gacatacgag ttggctgaat cgcttttgaa ggcaaaagaa
    24121 ctggctgcta cccaagggta cggattgctt ctatgggacg gttaccgtcc taatcgtgct
    24181 gtaaactgtt ttatgcaatg ggctgcacag ccggaaaata acctgacaaa ggaaagttat
    24241 tatcccaata ttgaccgaac tgagatgatt tcaaaaggat acgtggcttc aaaatcaagc
    24301 catagccgcg gcagtgccat tgatcttacg ctttatcgat tagacacggg tgagcttgta
    24361 ccaatgggga gccgatttga ttttatggat gaacgctctc atcatgcggc aaatggaata
    24421 tcatgcaatg aagcgcaaaa tcgcagacgt ttgcgctcca tcatggaaaa cagtgggttt
    24481 gaagcatata gcctcgaatg gtggcactat gtattaagag acgaaccata ccccaatagc
    24541 tattttgatt tccccgttaa ataaactttt aaccgttgca cggacaaact atataagcta
    24601 actctttcgg caggaaaccc gacgtatgta actggttctt agggaattta tatatagtag
    24661 atagtattga agatgtaagg cagagcgata ttgcggtcat tatctgcgtg cgctgcggca
    24721 agatagcctg ataataagac tgatcgcata gaggggtggt atttcacacc gcccattgtc
    24781 aacaggcagt tcagcctcgt taaattcagc atgggtatca cttatgaaaa ttcatctaca
    24841 ttggtgataa tagtaaatcc agtagggcga aataattgac tgtaatttac ggggcaaaac
    24901 ggcacaatct caaacgagat tgtgccgttt aaggggaaga ttctagaaat atttcatact
    24961 tccaactata tagttaagga ggagactgaa aatgaagaag ttgttttttt tattgttatt
    25021 gttattctta atatacttag gttatgacta cgttaatgaa gcactgtttt ctcaggaaaa
    25081 agtcgaattt caaaattatg atcaaaatcc caaagaacat ttagaaaata gtgggacttc
    25141 tgaaaatacc caagagaaaa caattacaga agaacaggtt tatcaaggaa atctgctatt
    25201 aatcaatagt aaatatcctg ttcgccaaga aagtgtgaag tcagatatcg tgaatttatc
    25261 taaacatgac gaattaataa atggatacgg gttgcttgat agtaatattt atatgtcaaa
    25321 agaaatagca caaaaatttt cagagatggt caatgatgct gtaaagggtg gcgttagtca
    25381 ttttattatt aatagtggct atcgagactt tgatgagcaa agtgtgcttt accaagaaat
    25441 gggggctgag tatgccttac cagcaggtta tagtgagcat aattcaggtt tatcactaga
    25501 tgtaggatca agcttgacga aaatggaacg agcccctgaa ggaaagtgga tagaagaaaa
    25561 tgcttggaaa tacgggttca ttttacgtta tccagaggac aaaacagagt taacaggaat
    25621 tcaatatgaa ctatggcata ttcgctatgt tggtttacca catagtgcga ttatgaaaga
    25681 aaagaatttc gttctcgagg aatatatgga ttacctaaaa gaagaaaaaa ccatttctgt
    25741 tagtgtaaat ggggaaaaat atgagatctt ttattatcct gttactaaaa ataccaccat
    25801 tcatgtgccg actaatcttc gttatgagat atcaggaaac aatatagacg gtgtaattgt
    25861 gacagtgttt cccggatcaa cacatactaa ttcaaggagg taaggatggc ggaatgaaac
    25921 caacgaaatt aatgaacagc attattgtac tagcactttt ggggtaacgt tagcttttta
    25981 atttaaaacc cacgttaact aggacattgc tatactaatg atacaactta aacaaaagaa
    26041 ttagaggaaa ttatattggg aaaaatatta tctagaggat tgctagcttt atatttagtg
    26101 acactaatct ggttagtgtt attcaaatta caatacaata ttttatcagt atttaattat
    26161 catcaaagaa gtcttaactt gactccattt actgctactg ggaatttcag agagatgata
    26221 gataatgtta taatctttat tccatttggc ttgcttttga atgtcaattt taaagaaatc
    26281 ggatttttac ctaagtttgc ttttgtactg gttttaagtc ttacttttga aataattcaa
    26341 tttatcttcg ctattggagc gacagacata acagatgtaa ttacaaatac tgttggaggc
    26401 tttcttggac tgaaattata tggtttaagc aataagcata tgaatcaaaa aaaattagac
    26461 agagttatta tttttgtagg tatacttttg ctcgtattat tgctcgttta ccgtacccat
    26521 ttaagaataa attacgtgta agatgtctaa atcaagcaat ctgatctttc atacacataa
    26581 agatattgaa tgaattggat tagatggaaa acgggatgtg gggaaactcg cccgtaggtg
    26641 tgaagtgagg ggaaaaccgg tgataaagta aaaagcttac ctaacactat agtaacaaag
    26701 aaagcccaat tatcaatttt agtgctgagg aattggtctc tttaataaat ttccttaacg
    26761 ttgtaaatcc gcattttcct gacggtaccc ccaaactaag atttcataga tagattttct
    26821 gataacttta aaaaacacga atagcggaaa ggatgtcttc attcgctaaa gagtaataaa
    26881 ctacttttcc atcttgacgt gattttgcca ttccatgttt ttttaaaaaa cgtaaatggt
    26941 gtgacgttgt agcgacacta gcagtaagta tttctgctaa atcacagacg cacatttcct
    27001 tataggtttc taaagcatag aaaattttaa ttctagaaaa atcgctgaaa catttcccta
    27061 acacaagtaa gtttgaaaaa tctttttgat ccaatttatt ttttattcca tttacttttt
    27121 ctttatgtac gacagtcact tggcaaactt ttttcattca tctcacctca cattcaaacg
    27181 attatttgaa tgaagtatac ctatttgatc actcttttgt caatctacct taattccaat
    27241 acactattat aagcaatttc atgtattgaa gtaaacttac ttgcaagtgc gtttttgatt
    27301 ccaagttaaa aacatattat tattctacat aatttcctaa tcaaataaaa ctcctttgaa
    27361 aattgttcta aaggagtttt attattttgt atttctacta aaaatagcgt acaatgtaat
    27421 tactaagtaa ttacgaaatg taaaataatg gaggaaataa tatgattaca aaaacaagaa
    27481 aacaaggaaa ttctattatg ttaacggtcc ctaaagaatt cgatgtgccc aatggtgttg
    27541 aagtagaagc taagcttgta gagaatggta tcctttatga gtttgtagag cctaaaaaag
    27601 aattttttga ttttagtgaa gatattttgg ctgatattct ttcagaaggt tatagcaaac
    27661 aagagatctt aaaagaattt agaaatagaa aaaatgcgtt aacttctgca tttaaatcta
    27721 ttgctgaaga tactgttgca aattctaaac cgatgacaaa agaggagttg gcagcagaaa
    27781 ttggcttatg agattctacc ttctaaacac gtaataaagt atctaaaaaa attaaaagag
    27841 aaaacattaa aagaacaatt tttaacgata atttatgatg agatagcagt tcgtcctcat
    27901 tcgggagaac aaaaaacggg tgatttatca ggaatttggg ctattggatt caagtatgca
    27961 ggtacgacat atcgcgttgc atatgaaatt aaagataatg cagtgatacc tatcttacta
    28021 tgtggaacgc atgaaaattt ttatgaacaa ttaaaaaaga ttaggtaaga acccaatgtt
    28081 tcaacttgag aggatagacg acactttaaa agataatttt taacagctga gagttgtaat
    28141 accctataat tttaaaccac taacctatat atttatgaaa aatagaaaaa attaaaacgc
    28201 attttaagcc tctttcaaat taaaagcttc atccttatgc acaaagaggg cttaaaatgc
    28261 gttattttat attgtttttt agtaataata aaaaaatcac tctaattctc ccataaatat
    28321 tatagattcc taaagattaa aatagattat tccctattgt cttttaagta gcggtagagt
    28381 gttgccttgc taataccagt catttccgta atttctttta cgctataaac ctgactttta
    28441 tacaatttta ctgctcgatc aacatctttc tggttcactc gtggacggcc acctttacga
    28501 cctctcgcac gtgcactttt caaaccttct ttggtacgtt caacaattaa atcacgttcg
    28561 aactgactaa atgcttggaa gacagtcatc attaagcgtc cgtgaggcgt gctggtatcg
    28621 aagttttctt tcaagctcac cagcttaaca tggtgttctt caaaataggt aacaaggtca
    28681 atcaaatcct ttgtactacg acccaatcga gaaaaacttt ctacaattac cgtatctccc
    28741 ggacgaattt tatcttttaa acgatttagt tggggacgaa ccgctttggt tcccgtcatt
    28801 ttctcagtta ggatttcatt acaattttgt tcattgagta agtctaattg acgatttagt
    28861 tcttgtgaac gtgtactcac tcgggcataa ccataaatgt atccactcat gcttttcttc
    28921 ctttcgtact ttaattctgg cttgattgta tcataaaagg gagttataga tacatagtta
    28981 atgcaacaag ttatgataca aaatatgacc tcttttattt aataaaagag gtcatttcat
    29041 tttgtctcat aatcgattgt ttttgatacg agtgtgtata cgaaataaac aaaaaaatct
    29101 taagtaaatt tctagatacc taatttaatc ctaactagtg tatcctaaag ttaataacga
    29161 gtttatcaca atgaaaatta taaaatgctc ccatattaga tataacatgc aatatttgaa
    29221 ttagaactac aaaatttatt cgttttataa agtaaataat gttgagatac taaggaatag
    29281 aatattataa ggaattgagc tgaatgtatt ggataaaaaa agaataactt tattagagat
    29341 ggactataaa aatgctcgta attttcttct gaagtctgaa agctatttga atgctcagct
    29401 accagaatat attagttttg acgaaacttt aaaatctgct aaaaaagttt taacttcgcc
    29461 gtttgtataa ttaagcgaga caaataaaaa agccatttat gttacactca aattgtaata
    29521 cccgctaaag catacaagga gagtgaacat aaatgactta tacccatctt acaccaaacg
    29581 agcttgtaat gatagaagca tattttcatc aagaaactcc ggttgctatc gttgcgaagc
    29641 agcttaaacg tggacgccaa acaatttaca atgtctataa ctttctcaaa tgtggtggaa
    29701 cagcacttga atactttgaa caatacaaag aaaataagcg acgttgtggg agaaccgaaa
    29761 tcatttttcc tgctgaggaa aaagaataca ttgaaaaaag atcaactgaa ggttggaccc
    29821 cagacgtcat tattggccgt gcagagcgaa ccttctcttg ttcaataagt accctctatc
    29881 gccggtttaa gacgggagaa ttcaatgttt tacatttacc gatgcaagga aaacgaaaac
    29941 caaatggtta taaggaaaaa cgtggaaaac aggcattcaa aagaaatatt tctgaacgta
    30001 aaaaagatta tgtcgttttc gaagaagaat ttggacattt agagggtgat acgattgtcg
    30061 gcatccacca taaaagtgcc gtcatcacac tcgttgagcg actttcaaaa gccattatcg
    30121 tcttgaaacc agaaggccgt aaggcagttg atattgaaaa ttcgattaat gaatggcttc
    30181 aatccgtacc caaaaatctt ttcaaatcaa ttacctttga ttgtggaaaa gaattctcta
    30241 attggaaaag tattagtaat acgaatgata ttgatattta tttcgcagac ccaggaacgc
    30301 cttcccaacg gggattaaat gaacattcaa acggactcct ccgaaaagat ggactaccaa
    30361 aagaaatgga cttcaaccaa gtcaatcaag gattcatctc atccgttgcg tccaaaagaa
    30421 accatatccc tagaaaatca ctaaattacc aaacaccatt agaagttttt ttgagttacg
    30481 taaatggaaa gttttgtctc gcttaatttg acaaataata cttcaaaaaa aaaccaaccg
    30541 aaagatataa aagatattgt agatacacga atgtataaag aacgtgatga cttaaactat
    30601 acgcttatta tcaataaaga tggaaactat tcatggcgtc ctctcgttct actacatcct
    30661 attctatatg tagatttggt taattgtctc actaaagaag accattggga ggagttaaaa
    30721 aagaggttta gtgaatttaa aaaagataaa aatattaact gttattctat acctgttgaa
    30781 gcttccaaag gttcaaaaag gacagatctt ggtgaaacaa tactaaactg gtgggaatat
    30841 tttgaacaaa aaagcttagc tcagaatatt aaataccaat attgcatgtt tactgacatc
    30901 gctgattgtt atccatcaat ttatactcac tctataacat gggccatgta tggtaaagaa
    30961 aaagttaaaa atgatgaaaa taagtgttcg ggctcacttg gcgataaaat agataaaaaa
    31021 atatctggaa tgcaacacaa tcaaacaaat ggtatccctc agggttccgt tcttatggat
    31081 tttgtagcag agatcgttct agggtatgtt gatttgagat tatcgaaaga attaaaaaaa
    31141 ttagaaaatt taaaagatta caaagtactc agatatagag atgattatag aatattttca
    31201 aataatcgta atgatttgga acaaattatg aaagtgttat cagaagtctt atatgattta
    31261 aattttaagt taaattctag taaaacaaaa ttatcagatg atattatcat agattctatc
    31321 aaaaaagata agctctattg ggaagaaatt aaggcaagta taagaatgaa tgccacaaac
    31381 ttagatggtg atagagaaat tcgttatagt ataaatttac aaaaacattt attggaaata
    31441 aaaaagttag cagataagca tcctaattca ggccaattga aaaaagcact ttctgagttt
    31501 aataaagaac gcattattaa aatcacttca aagccgaacg atcttttacc acttattggt
    31561 atcctggtag atatcatgat aaataacccg ggttctttgc cgcagtgtgt cttaattata
    31621 gggcagttat taaatttcga aaatgagagt aaggctagag aaatagttga aatgattata
    31681 aacaaatatg ctttaaagcc aaatactgaa tttatgatga tatggtttca aagattgacc
    31741 accatttttg gagaaatgtt tgatagtgtt ttatcatccg aatttgtatc taaaatcaaa
    31801 gatcctgtct ctaatcagat gttttctgta gactggctaa atgaagatgc taagaaatct
    31861 ttttatgaag ggaccattaa agacgaagag aaatatatta aaatgagtaa gaaaatatat
    31921 attactgaat ttgatgattt taatgattat cctttttaag tgaaaattta gaatgaatat
    31981 aaaaaacatt acaatctaat ttttttaaaa aaatgttata tcggaagtaa tctcttgatt
    32041 tctatactat aagataagaa aaccactatt taacaaggtt attcgaacct tattttaagt
    32101 tacttattat ttaatgtatc gaaaaaggtg aaataggttt gttataataa gaattaagta
    32161 agacatgaat tgtctaagca aatgtagctt atccatttca ttaaaataca tatggtgaaa
    32221 aaacaagttc aaatagtaac taatttttta aaaaactgat ttataaaaaa tacaacacga
    32281 atgaggaaaa taaccaatga cagaacaaat cgaaaaaaat tcaaaaagct tatatcaggc
    32341 actgtggaat tccgcagata tcctgcgttc aaaaatggac gctaatgaat acaagagcta
    32401 tttactaggc ttggtctttt ataaatactt atccgacaac atgctgcggt atgtctccgt
    32461 tctattggag gaagaaacgg acgacctaaa taaagcacaa gacctttacg ttgaagcatt
    32521 taaagatgca gatataaagg atgatctctt gtatgaacta aaagatgagt tttcatatac
    32581 catcgcaccc gcattgacct ttaccgcgca agtggcagcc attcatgatg gatcttttca
    32641 attagaagac ctggtacaag gtttccgtga cattgaacaa tccagcgaaa actttgagaa
    32701 cttatttgaa gacattgatc tgtattctaa aaaactgggg tcaaccccac aaaaacaaaa
    32761 taaaaccatc gcagatgtta tgaaagaatt agaagggtta aacatggcgg ggcatgctgg
    32821 cgatgtctta ggcgatgcct atgagtactt aattggccaa ttcgcatctg aatccggtaa
    32881 aaagccggtg aattctatac cccacaaccg gtcgcaaaat tgatgacaca aattgtttta
    32941 caaggaaaag aagataaaaa aggcttttct gtttacgacg cgaccatggg ttcgggctcg
    33001 ttacttttga acgctaaaaa atattcccat caaccgggaa ccatttctta tttcggacaa
    33061 gagttgaata cgtctaccta taatttggcg cgtatgaaca tgattttgca tggggttccc
    33121 attgccaacc aacacttgca taatgcggat accttggatc aagactggcc aacagaagag
    33181 ccaacgaact tcgatggggt gctcatgaac ccaccgtatt ctgcaaaatg gtcggctgat
    33241 aaaggcttct tagatgaccc acgcttctct gcctatggcg tattagcccc taaatcaaaa
    33301 gcggactttg ctttcttatt acatggctac tatcatttga aagatacggg cgtcatggcc
    33361 attgttttgc cacatggggt gctctttaga gggggcgcag aagggaagat acgcaaagcc
    33421 ttgttagaaa atggtgccat tgacaccgtc attggcttac ctgctaacat cttctttaat
    33481 acgtccattc caacgaccgt aattatcttg aagaaagacc gtgcgaaaaa agatgtgctc
    33541 tttattgatg cgtcacaaga ttttgaaaaa ataaaaacgc aaaatacgct acgagattac
    33601 catattgacg ctattttaga ggcctataaa acccgtacaa ttaaagacaa gtatgcttat
    33661 gtcgcagaat ttgatgaaat tgtggagaat gattacaact taaacattcc ccgttacgtg
    33721 gatacctttg aagaagaaga agggttctgt tgcaaagttt taaataaaga ataaaatccc
    33781 ttacggtatc tatgatttaa gctgggattc ccaataatac cttgatttca gtacagaccg
    33841 aaaacccgaa gagagtgcct tcttttcggg ttttcttata taatcctcga atggcttcca
    33901 tgcctttaat cgtggtagag gcagtgcgta aacttcgata gaatttattg cgtctcttta
    33961 ctggacgatg gtcttgttca atcaaattat tcaggtattt aatggtacga tgttctgtcc
    34021 cttgataaaa gccgtattct tttagtttct taaaggcact tgtaatagag ggggctttat
    34081 ctgtgactac aaccttcggt tcatcaaact gcttcactaa ccgcttaaga aaagcatagg
    34141 ctgcttgtgt gtcccgtttt ttacgtaacc aaatatccaa ggttaaacca tctgcatcga
    34201 tggctcgata caaataatgc cattttcctt taattttgat gtacgtttca tccattttcc
    34261 atgaataaaa ggatttttta tttttctttt tccaaatttg atagagtagt ttgccatatt
    34321 cttgcaccca acgataaatc gtcgtatgag aaacgttaat gccacgatca tataagattt
    34381 cttgaacttc acgatagcta aggttataac gaagatagta gcccacggct acaataatca
    34441 catcctgctg aaattgcttt cctttaaaat gattcatcgt cattcctcct gctatctttt
    34501 tctattattc taccttattt gatagtagat ttaaaacttt gcaacagaac cgtagcgatc
    34561 actccttctt acagcgacca tagggagcta gattggcagt ttaatatcat gcgcgaacct
    34621 gtttatttta aaaagtgggt gattttttgg cgggaaattt tgctcgcgcg cgcgcgttta
    34681 ttttatttat tttttaaaga ttttttagaa ccctttttag ggggcagttg agccttactc
    34741 tcccaacgga tacagaaggg tactaacaac tttttatctg agtactaaca actttttatc
    34801 tgagtactaa caacttttta tctgagtact aacaactttt tatctgagta ctaatatcct
    34861 tttgtataat aacaaccaac ctatttacga gttggttgtt aaaggttatt atttatttgt
    34921 aaggggggga agaaaggaat ggatgaaaaa acggaatggt tctgttgcaa agttttaaat
    34981 aaagaataaa atcccttacg gtatctatga tttaagctgg gattcccaat aataccttga
    35041 tttcagtaca gaccgaaaac ccgaagagag tgccttcttt tcgggttttc ttatataatc
    35101 ctcgaatggc ttccatgcct ttaatcgtgg tagaggcagt gcgtaaactt cgatagaatt
    35161 tattgcgtct ctttactgga cgatggtctt gttcaatcaa attattcagg tatttaatgg
    35221 tacgatgttc tgtcccttga taaaagccgt attcttttag tttcttaaag gcacttgtaa
    35281 tagagggggc tttatctgtg actacaacct tcggttcatc aaactgcttc actaaccgct
    35341 taagaaaagc ataggctgct tgtgtgtccc gttttttacg taaccaaata tccaaggtta
    35401 aaccatctgc accgatggct cgatacaaat aatgccattt tcctttaatt ttgatgtacg
    35461 tttcatccat tttccatgaa taaaaggatt ttttattttt ctttttccaa atttgataga
    35521 gtagtttgcc atattcttgc acccaacgat aaatcgtcgt atgagaaacg ttaatgccac
    35581 gatcatataa gatttcttga acttcacgat agctaaggtt ataacgaaga tagtagccca
    35641 cggctacaat aatcacatcc tgctgaaatt gctttccttt aaaatgattc atcgtcattc
    35701 ctcctgctat ctttttctat tattctacct tatttgatag tagatttaaa actttgcaac
    35761 agaacccgaa gaacaattgt atttggaaag tgaaacgagt caaacgaagg tcacagtcag
    35821 ccataatcgt ttagacgtgt ataaacgtcg tcctgaaacg gtaaaaaaag gaacggagct
    35881 tctacgacta gaaacagaaa aatacatcat gaatgtttac ctagaaagga gtgagctggt
    35941 cgaaaacttt gtcagctaca cgatttgcag gaaacactat tactcagaat cagaatatta
    36001 ttcaattttt gagagcatgg aattaatgga agaagaaatg gaagagctaa acagcaaaga
    36061 tgcgacgata gacgattatt accttgtatt tactagattt ttgacgtgtg gaacggaatc
    36121 tatcgtgtta atgggaatgg attatgaact cgctgtaccc gaagcatttt tgagggaata
    36181 tgtagaagaa gtagataacc caggcgacga ctggtacacg actttaactg attttttaga
    36241 cacctatact tacgacgata cagaagaaat ccaaaatgaa cttgaccgta aacgaatgcc
    36301 atatcaacga tttgaaagga aaaaaaggca ataatcattt ataccgaaaa gtgagaatgt
    36361 gtgaaataag gacaaaaaac ctagtaacta agggaatggt tcttatttcg caccaatcgc
    36421 tccaaccgcc cccgccgctt aggtggtgcg aaataagcgg gcaacacccg ataacctaag
    36481 agaaagaagg agatccatat gaataaaatc attcctctat tgttagtcct atttgttggc
    36541 gaaatactta tgcgccatgc tgcagctgtg catttaaact tcgtagtatt tttggcaata
    36601 ctggtatttt gtttgatctt ttggcgcttt gtattagccc ttgtgagtct actattcaag
    36661 atgattgcag ccatattttt catagggtta tttcgatgaa aggagagagt actaatgcca
    36721 attgcaatag gaaataaacg gttacccgtt acgttggatg aaaagagaca aaaagaattg
    36781 cagcaactaa agcagaagta cggcaaaagt gaatccagga ttatgtgtat tgcgttagat
    36841 ttattgattg cccaagaaaa agcaggattt gaggtaccag cactcaaaaa gtgacgtcac
    36901 tttttatcct aaaaactaaa agtgatagca cttttaatta taagaagtta gaatattaat
    36961 catttgctta attgtacaat ataatgtaca attgttttat agaaataaat aaggggtgaa
    37021 aggaatggaa gcagtagctt attcaaattt ccgccaaaat ttacgtagtt atatgaaaca
    37081 agttaatgag gatgctgaaa cacttattgt aacaagtaaa gatgtagaag atacagttgt
    37141 tgtattatca aaaagagatt atgattctat gcaagaaacg ttgagaacac tttctaataa
    37201 ttacgtcatg gaaaaaattc gtcgaggaga tgaacaattc tccaaaggtg catttaaaac
    37261 acatgactta atcgaggttg aatctgatga ttaaggcttg gtctgatgat gcttgggatg
    37321 attatcttta ttggcatgag caaggaaaca aaagcaatat aaaaaagatt aacaagttaa
    37381 taaaagatat cgatcgttcc ccctttgctg gattaggaaa acctgagcca ttaaagcatg
    37441 atttatctgg aaaatggtcc agaagaatta cagatgaaca tagactgata tatagagttg
    37501 aaaatgaaac gatatttatt tattctgcaa aagatcacta ttaaccaatc ggaagtaagg
    37561 aaagggtcag aaacttaaaa gtttttgatc cttattttat ttaccctagt catttaaaaa
    37621 gctaatatag cttagtgttg attgttatta atgaatgtgt ttgttacgcg tattacggat
    37681 ataaggttag taaaatcatt tctaaagttg aggaaaagta aatataaatg gcttaaattt
    37741 caacaatttg aagttgaata gatatgttat aatactattg tagtgtggga tgttagttac
    37801 taaaggatga cgcttatata tatgactgaa tagaataagc aataggttta ataatctatt
    37861 ttaaattttt tgtactagtt ttagttaatt agcaaaaaca acaaaaataa acttctcata
    37921 gaatttagct aaaaattaat gatttattta catattaaat ttggatacag ttaagtaatt
    37981 tttatatatt ggaggagaag taatggaata taaatttaac ttgaatttga aagaagtact
    38041 ccccactcag ggaacaataa acataaatgg tcaagataat gatgacgata tagtaataaa
    38101 aaaaatagaa tttattgatt ctgatataaa tgtttttttt tattctaaag aaaaattagc
    38161 tgattttagc aatattgctg aaatgattga acgtttaaaa gattttatga tcagtgtttg
    38221 ggatgtagcg atgcttgctg acgaatcaaa ttatacttcg agcatataca gattagaaga
    38281 tagtaattgg atagaaattt cattagagtt aaagacactt cctaattccg ttaactatat
    38341 aattagagat ataacttctg aagctcaaca attagttaat tacatgcatg gacacgaaag
    38401 tatccccttt tctcttatac tccttaaaag aagtaaaaat atatcaaata ctagagatag
    38461 gtttatttcg ataattacag cctgtgaaat aggggtaaag gaattttatc aacaagagaa
    38521 acctgattta actctaatat ttgagaattt acaatctccc cctgtagaca aattattagg
    38581 gagcatgttt aaagggtact ttaatattga gtttccgaaa gaaataagaa aggaaattaa
    38641 aaatttcata gaaaaacgta ataaattggt tcattctcct caaggaagta aaccaactat
    38701 agaagaatgt tttgaatgtt atatggcagt gctaaaaaca tttaattttt tttataaaat
    38761 taatgatagc tttatgtata gagattttta tgaagaatct atagaattga ctccaacgga
    38821 accaaataaa tctcaaatca ctttgtcaaa ggagctagag agaaaagtag agtctcaaga
    38881 actagctata ggaattagta taaccaatgt gtcgacatac aaagaattat acgaagctaa
    38941 atcacaagat aataaggatt ttgtagaaaa tatagataag gaaccaacaa atacagtagg
    39001 ggattaacgt aaataagtga agattatatt aacagactct ttatttagtt aagtaaaaaa
    39061 tggtttgttg gaattttatg ctttatctgt tctgagtaag acttaatttt atagatagta
    39121 attatatgta ggaaattaaa gatgagaaga taataaaagc agcatgatca actatttgtc
    39181 attgaccatg ctgtcttttt ttattctata cacggtttgt ctcgtaacat tgtagtcttt
    39241 agcaatctta gcaatcgcaa caccattttt aagatcttca acgatgcttt tgtaaacaag
    39301 gcgacgttgg ggatcttttg cgtctgcact gtataatttg ggccgccctt tgtagacgcc
    39361 gtttgctttt gcgatcttaa ttccttgtgc ctggcgacgt ttcgattcag tccgttcttg
    39421 ttcagcgatc atggccaaaa tttggatgat cagatcctta atgaatttat ccaggagagg
    39481 attgccaatt gcttcagcca tgatcggtaa actagtaatg atcagcttca catttttctt
    39541 cttcaagtaa ttgactgaag cgatgatctc gtcataattt cttccaagtc gatcaatagc
    39601 ttccacaata aaaatatctt gatctcggac gtaatctaat gcttcttgga aaacaggtcg
    39661 atgagtaatc gttgcgccag attgtttctc gatgaaaatt ctctctgcac cgaatttttt
    39721 catttcttca atctggcgtt gttcattttg atcgatcgat gagacacgta tgtatgcaac
    39781 tctcaaaact tttacctact ttctgcaact atttaaaata caccctaatc atacacgagg
    39841 aagccatatt tttcaatgtt ataccagtgt ctatttaggg taaaccttat atagacaaaa
    39901 actaatgatg gaggaaatag tatgagaatt ttttgtaagt gtctactgat aacttattct
    39961 caaatgttgt aaggatttta ttcatttgtt aatattaaag aacggaactc caaaaaagtc
    40021 cgtactctaa tttgcagtct ctcactcttt tagagtgaga gtttttatta gattttcaaa
    40081 ttaattagta aagtgataga ataaattgat catacaaatc aaaagaagaa gcagggtgat
    40141 agcataccta tgcttctttt tttatgtatt tagctatttc ttctttacaa tatcgaacat
    40201 atgtttgtat aatgtgaaag aatggagtgt tatttatgat ggattattca aaagagccag
    40261 taaatgatta ctttttaatc gatatgaaaa gcttttacgc aagtgtcgaa tgtatagaaa
    40321 gaaatttaga tccattaaca acagaacttg ttgttatgag tcgagctgat aatactggtt
    40381 caggattgat attagcttct tctcctgaag caaaaaagcg gtatggtatt acaaatgtga
    40441 gtagaccacg tgacttacca caaccatttc ctaaaacact acacgttgtt ccaccacgta
    40501 tgaacctata tatcaagcga aatatgcagg taaataatat tttcagaaga tatgtggctg
    40561 atgaagatct actgatttac tcgatcgatg aatcaatctt aaaagtgacc cgatcactga
    40621 atctttttac gactgaagga acacgaagtc aacggagaaa gaagctggct caaatgatcc
    40681 aggagaatat taaagaagag ctaggattga ttgctacagt aggtgtcgga gataatcccc
    40741 ttttggctaa actagcctta gacaacgaag caaagcataa tgaaggattt gttgcggaat
    40801 ggacgtacga aaacgttcct gaaaaagtat ggaatattcc tgaaatgacg gacttttggg
    40861 gaattggctc tcgaatgaaa aaaagactca atcagatggg gattatgagc attagagatc
    40921 ttgctaactg gaatccttat acgattaaga atagactagg tgtgattggc ttacagctgt
    40981 acttccatgc taatgggatc gatcgaacag atatagcaat cccaccagaa ccgacaaagg
    41041 aaaaatcata tggaaattca caagtgttac cacgagatta tactagaaga aatgaaatcg
    41101 agctggtggt aaaagaaatg gcggaacaag tagcgatacg cattaggcag cataactgta
    41161 aaacaggttg tgtccattta cacattggca cgtcgatctt agaaacgaga ccagggtttt
    41221 cacaccagat gaagatccct atcacagata atacaaagga attgcagaat tattgtcttt
    41281 tcttgtttga taagtattat gaaggacaag aagtaaggca tgttggaata acctatagca
    41341 agcttgtgta caccgattcg cttcagctgg atttatttag tgatccacaa aagcaaattg
    41401 acgaagaaaa tttagataaa attattgaca agattcggca aaaatatggt tttacgtcga
    41461 ttgtacatgc ttcttcaatg ttagaaggcg ctagaagcat tactagaagc acacttgttg
    41521 gtggtcatgc gggcggaaat gggggaatta aaaatgattg attacaatga tcgtggacgt
    41581 ttaaagtggg cagggtttta tttatctgat catactgaag aaattgatgc cgacaatgaa
    41641 caacgaacca gtcaaaattt agcaaaagaa caaatgacga ctgaagagat tgcggaagta
    41701 ttgaacgctg cagtcataaa aaatagatca gtatctattc aaaaagaaga acgaaacgct
    41761 gaaggatact atccagaaga tatcattggc aagatcttag gtagtgatga gctggggatc
    41821 tacgttggaa aagacaaaat tcactacgac gaaatacgtc atatcgaatt ttaccaggat
    41881 aataaatgga gtcgattaga atgaacatta tccagcaata tgagctaaag tatataacct
    41941 ttgatcagct atcagaagag atttggggtt atggccaacg tttgataaat gaggttggtg
    42001 ttgagcgctt ctctttctat gtagaagctg cagcaggtta tcataatttt aggttttata
    42061 tcttcccgtt atatatataa ggtattttac ggattctata gagttatctc tatgaatcct
    42121 tttttgtttt tacaaatagg agtagatact agaataatgc gtgtgttaaa ctattattgc
    42181 aaacgcaata ataaaagaaa gtaggcttac gcaccatgtc tatcaataca tttgtttact
    42241 cgcacccgat caatgtttac attatcaaga atttaggaat cactgtagaa caattttgtg
    42301 agttatatgc ctacccacaa ggaacggttg caagctggat aacccgacaa cgtagaataa
    42361 aatcattacc tgcttcattc gtttatgatt taagcctggc ctctagttta aacatgtctg
    42421 atgtttatga aaagctcctg tctttagaaa aagaatatga ttccttcaag attaaacatg
    42481 ataaaaaaat aaaaaaacat atataatatc aatcacaatt gtataatatt acgatatctt
    42541 aatatcatga tatcgtaata ttgttttttt ctaagaaaat gcactataag aagggaatta
    42601 ttagtaacaa tatagacagt ttagtaatgt ttaaattatt ctagttgctg ctcgcaaaac
    42661 atatttctta tcattaataa aaaattttaa agtaataaaa agtgattatt ttaatttcga
    42721 ataacatatg aataatcttt atatccgaac cgatatatat ctttaaaaca aaataatcac
    42781 acaatattac aatataatgc atatacgata ttgcaatatc acaatattat gatataatta
    42841 tattataata taagatgaat gggggatatt ttaatggcaa gaatattgtc agtagccaat
    42901 caaaaaggtg gagtttctaa aactacgact agcgttaatt tagcagcatg tttgaaattt
    42961 gtttacggta aaaatgtact tttagtggac attgatcctc agggaaatgc tacagataat
    43021 gtaggtttcg atatagatgg aacaaaccaa cctacaattt atgaagtatt aaaaggggag
    43081 gctgacatta cagatgctat tctggactat aaaggaattg atgttttgcc agccgacata
    43141 gccctttctt ctgcagagag ggaatttact caagtaggaa gtgaacacag gcttaaaaga
    43201 gtacttcaac caatcaagga caactatgat tatattataa ttgattgtcc accaagttta
    43261 ggaatgctta cagtcaacgc atttactgtt tctgatgaaa ttatcattcc agttgaagct
    43321 gcgtatttct cattaaaagg actaataaag ttaagtgaaa ctattgaaac ggtaaaagaa
    43381 tatacgaacg acaagcttga agtacgagga gttctattta ctaagtataa taagcgttat
    43441 aacatttcta aagaaatgac gtctgcagca accgaaattt ctagagtcat tggtgcaaaa
    43501 attttcaaaa cttatattcg taggacaata accgttgacg aagcgcaagc tgctggatca
    43561 gatctaatca attttaataa accctcaaca gctgaagatg actataaagc atttacagaa
    43621 gaatatttaa aagaagttgg tgattttgat ggcagaagat aatcgcagtc aagctgcagt
    43681 aagtagatta ctaggaaata aaaataaaaa gaattttaaa tcaaaagaag tagaagaaat
    43741 cgaattaacc aagaaaaata taagtaaagt cataaaagat caaggaagta gtgtaagaac
    43801 agcagatagc attcgtataa atccaattct aatgtcagca ctcaaatatt ggacgactat
    43861 tgctgaatca gacaaaagta aaccagacgt tatagaagat gcgctattaa agtccatacc
    43921 tgaagaatac ttgattgaag gatataaact agcaaagaaa caaaataaaa tttaatttac
    43981 attcaatatc acgatatcat aatatcgtga tatttttttt ataaaaatca gtagtatcaa
    44041 agctgataag tcgcttatct tcatattgta atattacgat atcgtgatat aatattattg
    44101 taatatcgtg atatagttac tatgagctta aaccttgaaa tagagcggtt tgctttaatt
    44161 tattttttaa ggtaaactaa aaaaagataa aaaaagacta ctgctttaac aaagtttggc
    44221 gacttatcag cagtagaaaa atatatagtg gatagatata tttgtttaat tcattgtaac
    44281 atagttttga acaaaacgct atcctacaga aagaggattg gct
//
