LOCUS       NZ_CP064428            43518 bp    DNA     circular CON 20-APR-2024
DEFINITION  Enterococcus faecium strain PR01996-12 plasmid unnamed_4, complete
            sequence.
ACCESSION   NZ_CP064428
VERSION     NZ_CP064428.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN16327730
            Assembly: GCF_018219325.1
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 43518)
  AUTHORS   Kinnear,C.L., Hansen,E., Morley,V.J., Tracy,K.C., Forstchen,M.,
            Read,A.F. and Woods,R.J.
  TITLE     Daptomycin treatment impacts resistance in off-target populations of
            vancomycin-resistant Enterococcus faecium
  JOURNAL   PLoS Biol 18 (12), e3000987 (2020)
   PUBMED   33332354
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43518)
  AUTHORS   Morley,V.J., Tracy,K.C., Kinnear,C.L. and Woods,R.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2020) Computational Medicine and Bioinformatics,
            University of Michigan, Palmer Commons, 100 Washtenaw Ave #2017, Ann
            Arbor, MI 48104, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 57x
            Sequencing Technology :: Illumina NovaSeq + Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018219325.1-RS_2024_04_20
            Annotation Date                   :: 04/20/2024 06:20:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,063
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 84
            rRNAs                             :: 6, 5, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 5, 6 (5S, 16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 209
            CDSs (without protein)            :: 209
            Pseudo Genes (ambiguous residues) :: 0 of 209
            Pseudo Genes (frameshifted)       :: 134 of 209
            Pseudo Genes (incomplete)         :: 66 of 209
            Pseudo Genes (internal stop)      :: 36 of 209
            Pseudo Genes (multiple problems)  :: 23 of 209
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP064428.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..43518
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /strain="PR01996-12"
                     /isolation_source="Rectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /plasmid="unnamed_4"
                     /geo_loc_name="USA: Ann Arbor, Michigan"
                     /lat_lon="42.28 N 83.72 W"
                     /collection_date="2016"
                     /collected_by="University of Michigan"
     gene            1..1041
                     /locus_tag="IUH71_RS15225"
                     /old_locus_tag="IUH71_15225"
     CDS             1..1041
                     /locus_tag="IUH71_RS15225"
                     /old_locus_tag="IUH71_15225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_000997689.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLLK
                     DRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGRVN
                     KRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTTVIA
                     KIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVDIMKE
                     DSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELESYGIDA
                     DKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFNELPTVS
                     TENWLE"
                     /name="replication initiator protein A"
     gene            complement(1657..2337)
                     /locus_tag="IUH71_RS15230"
                     /old_locus_tag="IUH71_15230"
     CDS             complement(1657..2337)
                     /locus_tag="IUH71_RS15230"
                     /old_locus_tag="IUH71_15230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_002287920.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIGADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            2483..2566
                     /locus_tag="IUH71_RS15235"
                     /old_locus_tag="IUH71_15235"
     CDS             2483..2566
                     /locus_tag="IUH71_RS15235"
                     /old_locus_tag="IUH71_15235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]; GO:0031556 - transcriptional attenuation by ribosome
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="WP_001814874.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
                     /name="23S rRNA methyltransferase attenuation leader
                     peptide"
     gene            2691..3428
                     /gene="erm(B)"
                     /locus_tag="IUH71_RS15240"
                     /old_locus_tag="IUH71_15240"
     ARG             2692..3425
                     /name="erm(B)"
                     /gene="erm(B)"
                     /gene_name="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /tool="amrfinderplus"
                     /drug_class="LINCOSAMIDE/MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            <3598..3858
                     /locus_tag="IUH71_RS15245"
                     /old_locus_tag="IUH71_15245"
                     /pseudo=""
     CDS             <3598..3858
                     /locus_tag="IUH71_RS15245"
                     /old_locus_tag="IUH71_15245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /GO_component="GO:0005694 - chromosome [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
                     /name="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            4021..>4686
                     /locus_tag="IUH71_RS15250"
                     /old_locus_tag="IUH71_15250"
                     /pseudo=""
     CDS             4021..>4686
                     /locus_tag="IUH71_RS15250"
                     /old_locus_tag="IUH71_15250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
                     /name="IS1182-like element IS1182 family transposase"
     gene            4722..4967
                     /locus_tag="IUH71_RS15255"
                     /old_locus_tag="IUH71_15255"
     CDS             4722..4967
                     /locus_tag="IUH71_RS15255"
                     /old_locus_tag="IUH71_15255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="WP_000567888.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRLL
                     LGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
                     /name="single-stranded DNA-binding protein"
     gene            5070..5939
                     /locus_tag="IUH71_RS15260"
                     /old_locus_tag="IUH71_15260"
     CDS             5070..5939
                     /locus_tag="IUH71_RS15260"
                     /old_locus_tag="IUH71_15260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing protein"
                     /protein_id="WP_000228166.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIYY
                     NSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIKRV
                     EQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETYPNA
                     LQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYCINEK
                     KAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINNFLNEE
                     SSDERKQI"
                     /name="nucleotidyltransferase domain-containing protein"
     gene            5920..6654
                     /locus_tag="IUH71_RS15265"
                     /old_locus_tag="IUH71_15265"
     CDS             5920..6654
                     /locus_tag="IUH71_RS15265"
                     /old_locus_tag="IUH71_15265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]; GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_000662263.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGKR
                     VLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDFPE
                     ESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNEKGE
                     ILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPENMMD
                     IPGMADEMRRPMMLIVSAKKKM"
                     /name="class I SAM-dependent methyltransferase"
     gene            6687..7595
                     /gene="ant(6)"
                     /locus_tag="IUH71_RS15270"
                     /old_locus_tag="IUH71_15270"
     CDS             6687..7595
                     /gene="ant(6)"
                     /locus_tag="IUH71_RS15270"
                     /old_locus_tag="IUH71_15270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="WP_048718102.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYDI
                     TYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLTLL
                     PLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNVTPY
                     VIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYISEDLW
                     EKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRDMYKKY
                     TGKTGCLDSTYAADIEERLTI"
                     /name="ant(6)"
     gene            complement(7704..8891)
                     /locus_tag="IUH71_RS15275"
                     /old_locus_tag="IUH71_15275"
     CDS             complement(7704..8891)
                     /locus_tag="IUH71_RS15275"
                     /old_locus_tag="IUH71_15275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297293.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="WP_002297293.1"
                     /translation="MYFLGIDIGKRTHVASIMNEEGKVLLKGFSFPNTTEGAESLIERM
                     VDYSGAPSDFVIGMEATGHYWLSIFSYLHESDYLIHVVNPLQTDGWRKGTEIRKRKNDI
                     IDSVLIADLMRYGSFVETVLSDENVFSLKQLSRYRTYLVGTASDFKRKIIAVLDQVFPE
                     YATIFTKQGVFGKASKELLLAFSAPIDLENISSETLAQYLAELSRNRIKAEKADQLKQA
                     ASNSFGVKFAQEAFTFQLRSMIEQLKFIESQIKETEREIKHIMDTLNSVILTIPGIGPI
                     NGATILGEIGDIQKFSNPKKLVAYAGIDASVTQSGQYEATHNVMSKRGSPYLRKALFSA
                     ALVASQCDPVFSAFYQKKVSEGKHHLTALGAVSRKLCYVIHAILTKNEPYIIVSD"
                     /name="IS110 family transposase"
     gene            9212..9754
                     /gene="sat4"
                     /locus_tag="IUH71_RS15280"
                     /old_locus_tag="IUH71_15280"
     ARG             9213..9751
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            9847..10641
                     /gene="aph(3')-IIIa"
                     /locus_tag="IUH71_RS15285"
                     /old_locus_tag="IUH71_15285"
     ARG             9848..10638
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(10784..12071)
                     /locus_tag="IUH71_RS15290"
                     /old_locus_tag="IUH71_15290"
                     /pseudo=""
     CDS             complement(10784..12071)
                     /locus_tag="IUH71_RS15290"
                     /old_locus_tag="IUH71_15290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /name="ISL3 family transposase"
     gene            12419..12961
                     /locus_tag="IUH71_RS15295"
                     /old_locus_tag="IUH71_15295"
     CDS             12419..12961
                     /locus_tag="IUH71_RS15295"
                     /old_locus_tag="IUH71_15295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="WP_002321977.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLEE
                     AGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAMYK
                     IKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPASGG
                     QEPESRMIEPVLLQSFK"
                     /name="HTH domain-containing protein"
     gene            complement(12991..13671)
                     /locus_tag="IUH71_RS15300"
                     /old_locus_tag="IUH71_15300"
     CDS             complement(12991..13671)
                     /locus_tag="IUH71_RS15300"
                     /old_locus_tag="IUH71_15300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            14988..16007
                     /locus_tag="IUH71_RS15305"
                     /old_locus_tag="IUH71_15305"
     CDS             14988..16007
                     /locus_tag="IUH71_RS15305"
                     /old_locus_tag="IUH71_15305"
                     /inference="COORDINATES: protein motif:HMM:NF019371.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="WP_010729551.1"
                     /translation="MKTSNRKYKVKTVNHRIPPKKALCVINNSKVINQELKPYLSEQEM
                     IKKISKDIFLTNSDTILLEKFLKKNSYFRFSIYVKLMKNIDKVTILDVIETYKLDSFIR
                     NQLHYFVNQIEIFWKKSLSDNMCVSYEETSIFPKNQCYLDKNIYSDLKWAEDIIGHFNS
                     FFYSNQSPTFKHHHIKKNHCLPIWALFEEITFGSLTTFINQLNTEYYNNWVMSCYDNPK
                     YKKAIRSWANVIRAYRNKIAHHSRIYAFKVTDAPTIIKNDSKSYFPENNLKETQKLYLY
                     GGLYVIKHLLIYEDSMTQTLWNKFLIDLEKKIDKIPSLEKSNYGFPENWRNKLKIMIV"
                     /name="Abi family protein"
     gene            complement(16509..16925)
                     /locus_tag="IUH71_RS15310"
                     /old_locus_tag="IUH71_15310"
     CDS             complement(16509..16925)
                     /locus_tag="IUH71_RS15310"
                     /old_locus_tag="IUH71_15310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002305824.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDVNNYSEAIRFLCMSYE
                     PDTNTTTTSNQAKLNAMGKEISIMTEIMAEFADLYLKDTGVLIGTNSKVYQEVKEKIEN
                     QLNPSRRNQPKNRQKETNQTFTSGNFDPTNFLKR"
                     /name="hypothetical protein"
     gene            complement(16927..17208)
                     /locus_tag="IUH71_RS15315"
                     /old_locus_tag="IUH71_15315"
     CDS             complement(16927..17208)
                     /locus_tag="IUH71_RS15315"
                     /old_locus_tag="IUH71_15315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000353845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000353845.1"
                     /translation="MDILVRNINPKIITRIDKRCQELTTKTGKKWSRNQYLKILIENDF
                     DHELMNYKKDQFDLLFEKFIAIQAENTNILNDYVHTNNQLIETLIGGI"
                     /name="hypothetical protein"
     gene            complement(17584..18108)
                     /locus_tag="IUH71_RS15320"
                     /old_locus_tag="IUH71_15320"
     CDS             complement(17584..18108)
                     /locus_tag="IUH71_RS15320"
                     /old_locus_tag="IUH71_15320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_002305828.1"
                     /translation="MTEKTIKELAEELGVSKTAINKKVSDENRKLWFSKIGNKFVINET
                     GQKAIKSMFFNENENSNQQLVGEKTKTENHKNANQVPELEVLSLLEQQLNQKDMQLQEK
                     DEQIKQMQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENKSTTLSEETESIEKQS
                     KTEKKWWQFWQ"
                     /name="DUF536 domain-containing protein"
     gene            complement(18125..>19006)
                     /locus_tag="IUH71_RS15325"
                     /old_locus_tag="IUH71_15325"
                     /pseudo=""
     CDS             complement(18125..>19006)
                     /locus_tag="IUH71_RS15325"
                     /old_locus_tag="IUH71_15325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332718.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /name="replication initiation protein"
     gene            complement(19062..19742)
                     /locus_tag="IUH71_RS15330"
                     /old_locus_tag="IUH71_15330"
     CDS             complement(19062..19742)
                     /locus_tag="IUH71_RS15330"
                     /old_locus_tag="IUH71_15330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            <19817..19930
                     /locus_tag="IUH71_RS15335"
                     /old_locus_tag="IUH71_15335"
                     /pseudo=""
     CDS             <19817..19930
                     /locus_tag="IUH71_RS15335"
                     /old_locus_tag="IUH71_15335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /name="helix-turn-helix domain-containing protein"
     gene            20144..20839
                     /gene="vanR-A"
                     /locus_tag="IUH71_RS15340"
                     /old_locus_tag="IUH71_15340"
     ARG             20145..20836
                     /name="vanR-A"
                     /gene="vanR-A"
                     /gene_name="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            20817..21971
                     /locus_tag="IUH71_RS15345"
                     /old_locus_tag="IUH71_15345"
     CDS             20817..21971
                     /locus_tag="IUH71_RS15345"
                     /old_locus_tag="IUH71_15345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-A"
                     /protein_id="WP_002305818.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGKL
                     GDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKYFD
                     EINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVMYLA
                     HDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRYNLQT
                     ITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFNNILKN
                     AAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSSDTGGAG
                     LGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
                     /name="vancomycin resistance histidine kinase VanS-A"
     gene            complement(22069..23361)
                     /locus_tag="IUH71_RS15350"
                     /old_locus_tag="IUH71_15350"
     CDS             complement(22069..23361)
                     /locus_tag="IUH71_RS15350"
                     /old_locus_tag="IUH71_15350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1251 family transposase"
                     /protein_id="WP_000122610.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIYT
                     AQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADTSV
                     AKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTPLPK
                     VLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREAVEWI
                     VIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQKHYQLG
                     KQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQLYQDFL
                     YAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPLECLNNHI
                     KVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
                     /name="ISL3-like element IS1251 family transposase"
     gene            23693..24661
                     /locus_tag="IUH71_RS15355"
                     /old_locus_tag="IUH71_15355"
     CDS             23693..24661
                     /locus_tag="IUH71_RS15355"
                     /old_locus_tag="IUH71_15355"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="WP_001059542.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKSA
                     PFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAYSP
                     DSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKAVIE
                     RLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQRMKQ
                     GAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQFLLKL
                     QRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
                     /name="D-lactate dehydrogenase VanH-A"
     ARG             24637..25685
                     /name="vanA"
                     /gene="vanA"
                     /gene_name="glycopeptide resistance gene cluster; Van
                     ligase"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="99.71"
                     /coverage="101.75"
     ARG             24655..25682
                     /name="vanA"
                     /gene="vanA"
                     /gene_name="D-alanine--(R)-lactate ligase VanA"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="99.71"
                     /coverage="100.0"
     gene            25691..26299
                     /locus_tag="IUH71_RS15365"
                     /old_locus_tag="IUH71_15365"
     CDS             25691..26299
                     /locus_tag="IUH71_RS15365"
                     /old_locus_tag="IUH71_15365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="WP_000402348.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTYE
                     LAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRTEM
                     ISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEAQNR
                     RRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
                     /name="D-Ala-D-Ala dipeptidase VanX-A"
     gene            26727..27638
                     /gene="vanY"
                     /locus_tag="IUH71_RS15370"
                     /old_locus_tag="IUH71_15370"
     CDS             26727..27638
                     /gene="vanY"
                     /locus_tag="IUH71_RS15370"
                     /old_locus_tag="IUH71_15370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="WP_000732308.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHLE
                     NSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLLDS
                     NIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGYSEH
                     NSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIRYVGL
                     PHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNLRYEIS
                     GNNIDGVIVTVFPGSTHTNSRR"
                     /name="vanY"
     gene            27791..28276
                     /gene="vanZ-A"
                     /locus_tag="IUH71_RS15375"
                     /old_locus_tag="IUH71_15375"
     ARG             27792..28273
                     /name="vanZ-A"
                     /gene="vanZ-A"
                     /gene_name="glycopeptide resistance protein VanZ-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(28563..28892)
                     /locus_tag="IUH71_RS15380"
                     /old_locus_tag="IUH71_15380"
     CDS             complement(28563..28892)
                     /locus_tag="IUH71_RS15380"
                     /old_locus_tag="IUH71_15380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000754864.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIKI
                     FYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDILS
                     AIRVF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            29197..29526
                     /locus_tag="IUH71_RS15385"
                     /old_locus_tag="IUH71_15385"
     CDS             29197..29526
                     /locus_tag="IUH71_RS15385"
                     /old_locus_tag="IUH71_15385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000629052.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEPK
                     KEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEELA
                     AEIGL"
                     /name="hypothetical protein"
     gene            29516..29803
                     /locus_tag="IUH71_RS15390"
                     /old_locus_tag="IUH71_15390"
     CDS             29516..29803
                     /locus_tag="IUH71_RS15390"
                     /old_locus_tag="IUH71_15390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_000312841.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQK
                     TGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(30082..30645)
                     /locus_tag="IUH71_RS15395"
                     /old_locus_tag="IUH71_15395"
     CDS             complement(30082..30645)
                     /locus_tag="IUH71_RS15395"
                     /old_locus_tag="IUH71_15395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000017403.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAVR
                     PQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTPHG
                     RLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQVYS
                     VKEITEMTGISKATLYRYLKDNRE"
                     /name="recombinase family protein"
     gene            31288..32241
                     /locus_tag="IUH71_RS15400"
                     /old_locus_tag="IUH71_15400"
     CDS             31288..32241
                     /locus_tag="IUH71_RS15400"
                     /old_locus_tag="IUH71_15400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="WP_002287760.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNFL
                     KCGGTALEYFEQYKENKRRCGRTEIIFPAEEKEYIEKRSTEGWTPDVIIGRAERTFSCS
                     VSTLYRRFKTGEFNVLHLPMQGKRKPNGYKEKRGKQAFKRNISERKKDYVVFEEEFGHL
                     EGDTIVGIHHKSAVITLVERLSKAIIALKPEGRKAVDIENSINEWLQSVPKNLFKSITF
                     DCGKEFSNWKSISNTNDIDIYFADPGTPSQRGLNEHSNGLLRKDGLPKEMDFNQVNQGF
                     ISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA"
                     /name="IS30 family transposase"
     gene            32219..33694
                     /locus_tag="IUH71_RS15405"
                     /old_locus_tag="IUH71_15405"
     CDS             32219..33694
                     /locus_tag="IUH71_RS15405"
                     /old_locus_tag="IUH71_15405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="WP_000443455.1"
                     /translation="MESFVSLNLTNNTSKKNQPKDIKDIVDTRMYKERDDLNYTLIINK
                     DGNYSWRPLVLLHPILYVDLVNCLTKEDHWEELKKRFSEFKKDKNINCYSIPVEASKGS
                     KRTDLGETILNWWEYFEQKSLAQNIKYQYCMFTDIADCYPSIYTHSITWAMYGKEKVKN
                     DENKCSGSLGDKIDKKISGMQHNQTNGIPQGSVLMDFVAEIVLGYVDLRLSKELKKLEN
                     LKDYKVLRYRDDYRIFSNNRNDLEQIMKVLSEVLYDLNFKLNSSKTKLSDDIIIDSIKK
                     DKLYWEEIKASIRMNATNLDGDREIRYSINLQKHLLEIKKLADKHPNSGQLKKALSEFN
                     KERIIKITSKPNDLLPLIGILVDIMINNPGSLPQCVLIIGQLLNFENESKAREIVEMII
                     NKYALKPNTEFMMIWFQRLTTIFGEMFDSVLSSEFVSKIKDPVSNQMFSVDWLNEDAKK
                     SFYEGTIKDEEKYIKMSKKIYITEFDDFNDYPF"
                     /name="RNA-directed DNA polymerase"
     gene            34032..>34172
                     /locus_tag="IUH71_RS15410"
                     /old_locus_tag="IUH71_15410"
                     /pseudo=""
     CDS             34032..>34172
                     /locus_tag="IUH71_RS15410"
                     /old_locus_tag="IUH71_15410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002961986.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit M
                     N-terminal domain-containing protein"
                     /name="type I restriction-modification system subunit M
                     N-terminal domain-containing protein"
     gene            complement(34231..34911)
                     /locus_tag="IUH71_RS15415"
                     /old_locus_tag="IUH71_15415"
     CDS             complement(34231..34911)
                     /locus_tag="IUH71_RS15415"
                     /old_locus_tag="IUH71_15415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(35029..35709)
                     /locus_tag="IUH71_RS15420"
                     /old_locus_tag="IUH71_15420"
     CDS             complement(35029..35709)
                     /locus_tag="IUH71_RS15420"
                     /old_locus_tag="IUH71_15420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            35910..36089
                     /locus_tag="IUH71_RS15425"
                     /old_locus_tag="IUH71_15425"
     CDS             35910..36089
                     /locus_tag="IUH71_RS15425"
                     /old_locus_tag="IUH71_15425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001120991.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLLI
                     AQEKAGFEVPALKK"
                     /name="hypothetical protein"
     gene            36220..36489
                     /locus_tag="IUH71_RS15430"
                     /old_locus_tag="IUH71_15430"
     CDS             36220..36489
                     /locus_tag="IUH71_RS15430"
                     /old_locus_tag="IUH71_15430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /GO_component="GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="WP_000388479.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKRD
                     YDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
                     /name="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
     gene            36482..36739
                     /locus_tag="IUH71_RS15435"
                     /old_locus_tag="IUH71_15435"
     CDS             36482..36739
                     /locus_tag="IUH71_RS15435"
                     /old_locus_tag="IUH71_15435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /GO_process="GO:0008219 - cell death [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="WP_000588503.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLGK
                     PEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
                     /name="Txe/YoeB family addiction module toxin"
     gene            37198..38202
                     /locus_tag="IUH71_RS15440"
                     /old_locus_tag="IUH71_15440"
     CDS             37198..38202
                     /locus_tag="IUH71_RS15440"
                     /old_locus_tag="IUH71_15440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000455809.1"
                     /translation="MEYKFNLNLKEVLPTQGTININGQDNDDDIVIKKIEFIDSDINVF
                     FYSKEKLADFSNIAEMIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACEI
                     GVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRNKL
                     VHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNKSQITL
                     SKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD"
                     /name="hypothetical protein"
     gene            complement(38367..38981)
                     /locus_tag="IUH71_RS15445"
                     /old_locus_tag="IUH71_15445"
     CDS             complement(38367..38981)
                     /locus_tag="IUH71_RS15445"
                     /old_locus_tag="IUH71_15445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001261742.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRPV
                     FQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGNPL
                     LDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQRRL
                     VYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
                     /name="recombinase family protein"
     gene            39431..40756
                     /locus_tag="IUH71_RS15450"
                     /old_locus_tag="IUH71_15450"
     CDS             39431..40756
                     /locus_tag="IUH71_RS15450"
                     /old_locus_tag="IUH71_15450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="WP_000969590.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRAD
                     NTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNIFR
                     RYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIATVG
                     VGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRLNQMG
                     IMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQVLPRD
                     YTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKIPITDNT
                     KELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEENLDKIIDK
                     IRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
                     /name="Y-family DNA polymerase"
     gene            40749..41099
                     /locus_tag="IUH71_RS15455"
                     /old_locus_tag="IUH71_15455"
     CDS             40749..41099
                     /locus_tag="IUH71_RS15455"
                     /old_locus_tag="IUH71_15455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000568378.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTEE
                     IAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIRHI
                     EFYQDNKWSRLE"
                     /name="hypothetical protein"
     gene            41096..41275
                     /locus_tag="IUH71_RS15460"
                     /old_locus_tag="IUH71_15460"
     CDS             41096..41275
                     /locus_tag="IUH71_RS15460"
                     /old_locus_tag="IUH71_15460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001021554.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAAA
                     GYHNFRFYIFPLYI"
                     /name="hypothetical protein"
     gene            41411..41701
                     /locus_tag="IUH71_RS15465"
                     /old_locus_tag="IUH71_15465"
     CDS             41411..41701
                     /locus_tag="IUH71_RS15465"
                     /old_locus_tag="IUH71_15465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000026576.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITRQ
                     RRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
                     /name="hypothetical protein"
     gene            42069..42857
                     /locus_tag="IUH71_RS15470"
                     /old_locus_tag="IUH71_15470"
     CDS             42069..42857
                     /locus_tag="IUH71_RS15470"
                     /old_locus_tag="IUH71_15470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302898.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA]"
                     /GO_process="GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000101106.1"
                     /translation="MARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVDIDPQGN
                     ATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAEREFTQVGSE
                     HRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLKGLIKLSET
                     IETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKTYIRRTITVD
                     EAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
                     /name="AAA family ATPase"
     gene            42844..43170
                     /locus_tag="IUH71_RS15475"
                     /old_locus_tag="IUH71_15475"
     CDS             42844..43170
                     /locus_tag="IUH71_RS15475"
                     /old_locus_tag="IUH71_15475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000796719.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKDQ
                     GSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLAKK
                     QNKI"
                     /name="hypothetical protein"
     ARG             23694..24658
                     /name="vanH-A"
                     /gene="vanH-A"
                     /gene_name="D-lactate dehydrogenase VanH-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             25692..26296
                     /name="vanX-A"
                     /gene="vanX-A"
                     /gene_name="D-Ala-D-Ala dipeptidase VanX-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             20818..21968
                     /name="vanS-A"
                     /gene="vanS-A"
                     /gene_name="vancomycin resistance histidine kinase VanS-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             26728..27635
                     /name="vanY-A"
                     /gene="vanY-A"
                     /gene_name="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="99.67"
                     /coverage="100.0"
     ARG             6688..7583
                     /name="ant(6)-Ia"
                     /gene="ant(6)-Ia"
                     /gene_name="aminoglycoside nucleotidyltransferase
                     ANT(6)-Ia"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="99.01"
     ARG             23694..24661
                     /name="vanH gene in vanA cluster"
                     /gene="vanH gene in vanA cluster"
                     /gene_name="vanH; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             20145..20839
                     /name="vanR gene in vanA cluster"
                     /gene="vanR gene in vanA cluster"
                     /gene_name="glycopeptide resistance gene cluster; vanR"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             26728..27638
                     /name="vanY gene in vanA cluster"
                     /gene="vanY gene in vanA cluster"
                     /gene_name="vanY; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="99.67"
                     /coverage="100.0"
     ARG             25692..26299
                     /name="vanX gene in vanA cluster"
                     /gene="vanX gene in vanA cluster"
                     /gene_name="vanX; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="99.5"
                     /coverage="100.0"
     ARG             27792..28276
                     /name="vanZ gene in vanA cluster"
                     /gene="vanZ gene in vanA cluster"
                     /gene_name="vanZ; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             20818..21972
                     /name="vanS gene in vanA cluster"
                     /gene="vanS gene in vanA cluster"
                     /gene_name="vanS; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="100.0"
                     /coverage="94.79"
     ARG             9225..9754
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="99.43"
                     /coverage="97.78"
     ARG             6688..7595
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="100.0"
                     /coverage="109.42"
     ARG             2692..3428
                     /name="ErmB"
                     /gene="ErmB"
                     /gene_name="Erm 23S ribosomal RNA methyltransferase"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; lincosamide antibiotic;
                     streptogramin antibiotic; streptogramin A antibiotic;
                     streptogramin B antibiotic"
                     /identity="98.37"
                     /coverage="98.79"
     Typing          2..1041
                     /name="rep_cluster_889"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(18130..19007)
                     /name="rep_cluster_1093"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.351"
                     /coverage="99.0"
                     /evalue="0.0"
ORIGIN
        1 atgaatgatt ttaattatta caaatcaaaa gaaatttatc gtgaaaaata ttatcaaatg
       61 cctaaggtat tttttactaa cgaaaaatac atggatctat caaatgatgc aaaaattgct
      121 tatatgctac ttaaagatcg atttgattat tcagtcaaaa ataactgggt agattctgat
      181 gataatatat ttttcatatt cacagttgaa gaattaatga aattgttaca atgccgcgaa
      241 ggtaaagtat ctaaaatcaa aaaggaatta gaaaaagcag gtcttctgaa acagaagaga
      301 ggaagagtaa ataaacgtga cggtaagatt gaatccatgc ctaatttatt gtacttaggc
      361 aagccagaag taacgaatca agacgtcttt aaaatcatgg aagaggaaga caatactgat
      421 accaccgtaa ttgcgaaaat cgcaaatacg gcaaaaccgc gagaaatcaa tgataccacc
      481 gtaattgcga aaatcgcaaa tacggcaaaa tccagtcata tcaaggactc aaccgtaatt
      541 gcgaaaatcg cagacaatct attctattct aattctatag acactaatag acacataata
      601 gacactgaaa ctgatcagtt acaaaatcaa gttttactag ataacttcgt cgacatcatg
      661 aaagaggaca gtataaatac atttgtacca gaaaatgtat taaacttgat aaaaacattt
      721 tctagtactt acgaagacgc tcaaaaaacc gtccaaacta ttcataatgc aaagaaaaaa
      781 gctgaagaat tagagcaaac agttgttgtt tatgaagaac tggaatctta tggaattgat
      841 gctgacaaag gattatatat gactttgctg aaagcttatc aaaaacaaaa aactgaaaaa
      901 gtaaacaatt tgcagaatct aattttcgtt tatgtaaaaa attggtttgt cgaaaaagct
      961 attgcggcaa agcttgcaaa cgaacaaaga gaaacattta acgaattacc aacagttagt
     1021 acggaaaatt ggctagagta gttgataaaa agcgatcact ataaaaatga tcaattttaa
     1081 attagaactt ttttatgatt ttaattttat tacaaatgtt acaaataaat agctattatt
     1141 ccggagtttt tagattaaaa gtttatgaaa acaatcacaa acgtaggttt taaagtcata
     1201 atcgttagat attttagtta tttttcattc aaaaaaatag ggaactagtg tttgcatatg
     1261 tgcttttttg agttataata attcatgaag agaggtaatt cacttatttc cccaagctga
     1321 aaagcctgat attacttctt ttcaggcagt gctgctaata ttcaattaca cttttttgta
     1381 tatttttagt tgttttaaat ttaattgtct gatatgcttg tgatgaattg attttcgttc
     1441 tgcacttttg gacgataaat tgtgataatt gaaaatacaa aaaaaagaaa ggcccctgta
     1501 aggctcggga gactggtaat ctccgtcagt gtcctacagg aaagcattaa gatgacgcct
     1561 taatgcgtgc ccttcagtgt tacggtatta cccgcaacgg acggttctgt tgcaaagttt
     1621 taaataaaga ataaaatccc ttacggtatc tatgatttaa gctgggattc ccaataatac
     1681 cttgatttca gtacagaccg aaaacccgaa gagagtgcct tcttttcggg ttttcttata
     1741 taatcctcga atggcttcca tgcctttaat cgtggtagag gcagtgcgta aacttcgata
     1801 gaatttattg cgtctcttta ctggacgatg gtcttgttca atcaaattat tcaggtattt
     1861 aatggtacga tgttctgtcc cttgataaaa gccgtattct tttagtttct taaaggcact
     1921 tgtaatagag ggggctttat ctgtgactac aaccttcggt tcatcaaact gcttcactaa
     1981 ccgcttaaga aaagcatagg ctgcttgtgt gtcccgtttt ttacgtaacc aaatatccaa
     2041 ggttaaacca tctgcaccga tggctcgata caaataatgc cattttcctt taattttgat
     2101 gtacgtttca tccattttcc atgaataaaa ggatttttta tttttctttt tccaaatttg
     2161 atagagtagt ttgccatatt cttgcaccca acgataaatc gtcgtatgag aaacgttaat
     2221 gccacgatca tataagattt cttgaacttc acgatagcta aggttataac gaagatagta
     2281 gcccacggct acaataatca catcctgctg aaattgcttt cctttaaaat gattcatcgt
     2341 cattcctcct gctatctttt tctattattc taccttattt gatagtagat ttaaaacttt
     2401 gcaacagaac cattttgtgt ataataggaa ttgaagttaa attagatgct aaaaatttgt
     2461 aattaagaag gagggattcg tcatgttggt attccaaatg cgtaatgtag ataaaacatc
     2521 tactgttttg aaacagacta aaaacagtga ttacgcagat aaataaatac gttagattaa
     2581 ttcctaccag tgactaatct tatgactttt taaacagata actaaaatta caaacaaatc
     2641 gtttaacttc tgtatttatt tacagatgta ataacttcag gagtgattac atgaacaaaa
     2701 atataaaata ttctcaaaac tttttaacga gtgaaaaagt actcaaccaa ataataaaac
     2761 aattgaattt aaaagaaacc gataccgttt acgaaattgg aacaggtaaa gggcatttaa
     2821 cgacgaaact ggctaaaata agtaaacagg taacgtctat tgaattagac agtcatctat
     2881 tcaacttatc gtcagaaaaa ttaaaactga acattcgtgt cactttaatt caccaagata
     2941 ttctacagtt tcaattccct aacaaacaga ggtataaaat tgttgggagt attccttacc
     3001 atttaagcac acaaattatt aaaaaagtgg tttttgaaag ccatgcgtct gacatctatc
     3061 tgattgttga agaaggattc tacaagcgta ccttggatat tcaccgaaca ctagggttgc
     3121 tcttgcacac tcaagtctcg attcagcaat tgcttaagct gccagcggaa tgctttcatc
     3181 ctaaaccaaa agtaaacagt gtcttaataa aacttacccg ccataccaca gatgttccag
     3241 ataaatattg gaagctatat acgtactttg tttcaaaatg ggtcaatcga gaatatcgtc
     3301 aactgtttac taaaaatcag tttcatcaag caatgaaaca cgccaaagta aacaatttaa
     3361 gtaccgttac ttatgagcaa gtattgtcta tttttaatag ttatctatta tttaacggga
     3421 ggaaataatt ctatgagtcg cttttttaaa tttggaaagt tacacgttac taaagggaat
     3481 ggagataaat tattagatat actactgaca gcttccaaga agctaaagag gtccctagcg
     3541 cctacgggga atttgtatcg ataaggggta caaattccca ctaagcgctc gggacccctt
     3601 gtaggaaaat gtcctaagtg tggcaacaat attgtattaa aaaaatcgtt ttatggttgt
     3661 tcaaattatc ctgaatgtaa gtttacttta gctgaacatt ttagaaagaa aaaactaacc
     3721 aaaacgaatg taaaagaatt actggaggga aaagaaaccc tggtaaaagg aatcaaaaac
     3781 aaagagaaaa agccctacaa tgccgttgta aaaattgggg aaaagggata tattgatttt
     3841 atctcttttt caaaataaac atggggctga cccaaaagta gctcctatat gaaaaataga
     3901 ggtctttcca tttagatagt agtggaaaga cctctattta tcttttgaaa gtgaatacaa
     3961 aaataaagca cactctgcta taatataggt gattaatcca tttgagagag gtgctttatc
     4021 atgtatcaaa attataccat aaaccaactt tgtttgccta tagatcttga aattaaatta
     4081 gaagaaaatg attttgctca tgccattgtg cagtttgttg actctattcc cgatgaagtc
     4141 tttcttcctt attatcaatc tatgggtaga ccccaatatc atcctcgtat gctactttcc
     4201 attattcttt gtgcctatat tcaaggggtt tattcgggcc gccaaataca aaatatgctg
     4261 atagatagta ttcggatgcg ctacttatct caagagcaat tccctaactt tcgtactatt
     4321 aatcgttttc gcgttcatcc gattatgaac gatattctag atcattcatt tgttcaattt
     4381 cgtgagctac tggttcaaag tggcttaatc agtggcagtg ctctatacat tgatggtaca
     4441 aaaattgaag cggatgcgaa taaatactct ttcgtttgga aaaaaagtat tttaaagtat
     4501 aaggatagcc ttgatcaaaa agcccttgaa aactaccaac aaatggtgga aacaaaaatc
     4561 ttacctgagt taatagatga tttaaaggat gaactttcta tagaagagat tgaaaggatt
     4621 cgtcaatctt tggaagaaaa ggaaaatcaa ttaattgaag cgattgacca aaccgaaaca
     4681 gtagaagggg gctgacccat tattaataag gagtggacaa catgattgat gtaaatgagc
     4741 tattggaaga agctattaga gaaactgaaa atctaaatga tggcgaagtt tttcttgtta
     4801 aagatttatt caagggatat gtggggaata ggatacccag aaaggatcga cttctgcttg
     4861 gaacgttatt tttaaaccat gttagcaaaa tgaatggtaa tttaaaggct attgaaaaga
     4921 cttcatctaa tcagcagagg tataaaaaga caattgataa gttttaacta tcttttgtga
     4981 aattaaaaaa attataaata tgttgagtag aagcaaaaga tttggcttgg aatttttaca
     5041 gcagtgaatc gataaaagga gcatgcttga tggtagataa tattattaaa tcagtagcag
     5101 agaaattatc ctctctgtct tatatagaag gtattgtttt aggtggttca cgtgcaaggg
     5161 gcacccatac agaggattcg gatatagata tcggcatcta ttacaattca gaatcatttg
     5221 acataaatac tattaatcaa ttcgctacaa agctggatga tgagcataga aataaccttg
     5281 ttgtacctcc cggagcatgg ggtgattgga ttaatggcgg cggatggtta gtcataaacg
     5341 ggtatcatgt ggatttaatt ttacgtgata ttaaacgtgt ggaacaaata atgaaagata
     5401 cagagcacgg aattgttact gccaattatc agactgggca tccccatggt tatattagtg
     5461 caatgtatcg aggagaatta gcgattagca aaatactata tgctaagaat gaaagcttat
     5521 gcgaattaaa aaaacaggca gaaacttatc ccaatgcttt gcagaaaagt ttagttaact
     5581 tttttatgtt tgaagcaggg ttctctttaa tgtttgtaaa agcaaattcg ggaacagacg
     5641 ataaatatta tattgcgggt catgtttttc gtatagtttc atgtttaaat caagtgttat
     5701 ttgcatgtaa taatgcttat tgtatcaacg aaaagaaagc tataaaactg cttgaaactt
     5761 ttgaacataa acctgaaaaa tataccgaga aggtaaatca tatttttgaa gtactcggta
     5821 tctcactttt tgaatgctac gacatgaccg agaagcttta taatgaagtg aatgaaattg
     5881 tatcggagat aaataacttt ttaaacgagg agagttcaga tgaaagaaaa caaatatgat
     5941 gataatatat tttttcaaaa atacagtcaa atgagtcgct cgcagaaagg actggctggt
     6001 gcgggagaat gggagacttt gaaaaagatg ctacctgatt ttaagggtaa gcgtgtgctt
     6061 gatttaggat gcggctatgg atggcactgt atatatgcga tggaaaacgg tgcttcctct
     6121 gtagtaggtg ttgatatttc tcataaaatg ctcgaagtag caaaaggaaa aacccatttt
     6181 ccacagattg aatatgaatg ctgtgccata gaagatgtgg atttcccaga ggagagcttt
     6241 gatgtaatac taagttcgct tgcgtttcat tatgtagcag actatgagaa tttaataaaa
     6301 aagatatata ggatgctgaa ggctggtggc aatttagttt ttacagttga acatcctgtt
     6361 tttactgctc atggaacaca agactggtat tataacgaaa aaggagaaat actgcatttc
     6421 ccggtggaca attattatta tgagggcaaa cggacagcta tgtttttgga agaaaaggtt
     6481 acaaaatatc atagaacact gaccacatat ctaaatacac tgctttcaaa tagttttata
     6541 ataaatcaga ttgtggagcc acagccgcca gagaacatga tggatattcc ggggatggcg
     6601 gatgaaatgc gacgcccaat gatgctgatt gtatcggcaa aaaagaagat gtaataatat
     6661 agaaaaaata aacgaggagt atgtaaatga gatcagaaaa agaaatgatg gatttagtac
     6721 tttctttagc agaacaggat gaacgtattc gaattgtgac ccttgagggg tcacgcgcaa
     6781 atattaatat acctaaagat gaatttcagg attatgatat tacatatttt gtaagtgata
     6841 tagaaccgtt tatatctaat gatgactggc ttaatcaatt tgggaatata ataatgatgc
     6901 aaaagccgga ggatatggaa ttattcccac ctgaagaaaa gggattttcc tatcttatgc
     6961 tatttgatga ttacaataaa attgatctta ccttattgcc cttggaagag ttagataatt
     7021 acctaaaggg cgataaatta ataaaggttc taattgataa agattgtaga attaaaaggg
     7081 acatagttcc gactgatata gattatcatg taagaaagcc aagcgcaagg gagtatgatg
     7141 attgctgcaa tgaattttgg aatgtaacac cttatgttat taaaggattg tgccgtaagg
     7201 aaattttatt tgctattgat cattttaatc agattgttcg ccatgagctg ctgagaatga
     7261 tatcatggaa ggtcggcatc gaaacaggct ttaaattaag tgtaggcaag aactataagt
     7321 ttattgaaag gtatatatcc gaggatttgt gggagaaact tttgtccacc taccggatgg
     7381 attcctatga aaacatatgg gaagcattat ttctatgcca tcaattgttc agggcggtat
     7441 ccggtgaggt ggcggaaagg cttcattatg cctatccgga gtatgatagg aatataacaa
     7501 aatataccag ggacatgtat aaaaaataca ctggtaaaac cggctgcctg gatagcacat
     7561 atgccgctga tatagaagag agactaacta tatagagtca agtaaaaatt agccaaatca
     7621 aaaaatattt tataacagat aattccgaaa aaagggtaca acaaataagc ttcttaccat
     7681 tagttttttt gaatgttcaa tagctaatca gaaacaatta tataaggctc gtttttagtc
     7741 aaaatagcat gaatcacgta acaaagctta cgagaaaccg cacctaaggc agttagatga
     7801 tgttttcctt cggaaacttt tttctggtaa aacgcactaa aaacaggatc acattgagaa
     7861 gctactaaag ccgccgaaaa caaggctttt cgcaaatatg gagaccctcg tttactcata
     7921 acattatgcg ttgcctcata ttgccctgat tgtgtcacgg aagcgtctat cccagcgtaa
     7981 gcaacgagtt ttttcgggtt agaaaatttt tgaatatctc cgatctcacc aagaatagtc
     8041 gcaccgttta taggaccaat tccaggaatt gtgagaataa cagaatttaa agtgtccatt
     8101 atgtgcttga tttctctttc cgtttccttt atttggcttt caatgaattt taattgttca
     8161 atcattgaac gtagttggaa ggtgaacgct tcttgagcaa attttactcc aaaggagtta
     8221 gaagctgctt gcttcaattg gtccgctttt tctgccttga ttcggttcct gcttaactca
     8281 gctaagtatt gggccaaagt ttctgaggaa atgttttcta agtcgatcgg ggcactaaac
     8341 gccagcaata actctttaga agcttttccg aaaacgccct gcttggtaaa aatcgtcgcg
     8401 tattctggaa agacttgatc caatacggct ataatttttc ttttgaagtc gctcgctgta
     8461 cctactaaat aagttcggta acgagaaagt tgtttcaaag aaaaaacatt ttcatcggat
     8521 aagaccgttt cgacaaatga gccatagcgc attaagtcag caatcaaaac agaatcaata
     8581 atatcgtttt ttcgtttccg tatttctgta cctttacgcc atccgtctgt ttgaagggga
     8641 ttcacaacgt gaatcaaata atctgattcg tgaaggtatg aaaagatgga cagccaatag
     8701 tgccccgtgg cttccatccc tataacaaag tcactgggtg ctccggaata gtcgaccatt
     8761 cgctcaatta atgactctgc tccttcagtg gtgttaggaa atgaaaaacc ttttagtaat
     8821 acctttcctt cctcgttcat gatagaagca acgtgagtgc gtttaccgat atcaatgcct
     8881 aaaaagtaca tgtatatctg acctttcaaa aaaagaattt tggattgaaa tccactcaac
     8941 tgaaaagcgt cactaccttg tacgagatac ggagtaaagt aaggactttc aacatctaac
     9001 tcatacgcaa tccacttatc agagagagga gccagtctct cgagtgcggg ttcaatggcc
     9061 caagggggga acggcttagc ctctcaatcc aataaatata ttatctcaaa agaaatgagt
     9121 taataccaaa ttaaaataac gatggttcat agggttatcc aatcaaaacc ggaaggttaa
     9181 aaccctaact ctaatataca aggcgggaac agtgattaca gaaatgaaag cagggcacct
     9241 gaaagatatc gataaaccca gcgaaccatt tgaggtgata ggtaagatta taccgaggta
     9301 tgaaaacgag aattggacct ttacagaatt actctatgaa gcgccatatt taaaaagcta
     9361 ccaagacgaa gaggatgaag aggatgagga ggcagattgc cttgaatata ttgacaatac
     9421 tgataagata atatatcttt actaccaaga cgataaatgc gtcggaaaag ttaaactgcg
     9481 aaaaaattgg aaccggtacg cttatataga agatatcgcc gtatgtaagg atttcagggg
     9541 gcaaggcata ggcagcgcgc ttatcaatat atctatagaa tgggcaaagc ataaaaactt
     9601 gcatggacta atgcttgaaa cccaggacaa taaccttata gcttgtaaat tctatcataa
     9661 ttgtggtttc aaaatcggct ccgtcgatac tatgttatac gccaactttg aaaacaactt
     9721 tgaaaaagct gttttctggt atttaaggtt ttagaatgca aggaacagtg aattggagtt
     9781 cgtcttgtta taattagctt cttggggtat ctttaaatac tgtagaaaag aggaaggaaa
     9841 taataaatgg ctaaaatgag aatatcaccg gaattgaaaa aactgatcga aaaataccgc
     9901 tgcgtaaaag atacggaagg aatgtctcct gctaaggtat ataagctggt gggagaaaat
     9961 gaaaacctat atttaaaaat gacggacagc cggtataaag ggaccaccta tgatgtggaa
    10021 cgggaaaagg acatgatgct atggctggaa ggaaagctgc ctgttccaaa ggtcctgcac
    10081 tttgaacggc atgatggctg gagcaatctg ctcatgagtg aggccgatgg cgtcctttgc
    10141 tcggaagagt atgaagatga acaaagccct gaaaagatta tcgagctgta tgcggagtgc
    10201 atcaggctct ttcactccat cgacatatcg gattgtccct atacgaatag cttagacagc
    10261 cgattagccg aattggatta cttactgaat aacgatctgg ccgatgtgga ttgcgaaaac
    10321 tgggaagaag acactccatt taaagatccg cgcgagctgt atgatttttt aaagacggaa
    10381 aagcccgaag aggaacttgt cttttcccac ggcgacctgg gagacagcaa catctttgtg
    10441 aaagatggca aagtaagtgg ctttattgat cttgggagaa gcggcagggc ggacaagtgg
    10501 tatgacattg ccttctgcgt ccggtcgatc agggaggata tcggggaaga acagtatgtc
    10561 gagctatttt ttgacttact ggggatcaag cctgattggg agaaaataaa atattatatt
    10621 ttactggatg aattgtttta gtacctagat ttagatgtct aaaaagcttt aactacaagc
    10681 tttttagaca tctaatcttt tctggctctt tgtcaaatga tgttggtaaa gagaaatctt
    10741 agaataattg gagatcaagt ggatcagttc ctcttgatct tttttagttg aaaatcaatg
    10801 cgttgccatg acgaatcatg atgcgcaatt tgaaattata aaagctacga aagccatatg
    10861 catttcgttt taacactttg atatggttgt tcagacattc aagtgggcca tttgaataac
    10921 tttgttgtaa agcatttttg atttgtggca gaaatttctg gaacgttctc aaggtcgtct
    10981 gatagccttc gggaagcatg atattattgg taagtagttc ttcaaacgat acgtagtctc
    11041 gttcctttac agcgtaaaga aagtcttgat ataactgata gcctacacgc aaagcagggc
    11101 tccctttcag taagcgatcc acaatatcgg tctctgttaa atgagctttg aagccaggtc
    11161 gccaaaggcg tcgagtataa tcaagcttgc gttcatcttt tgaagaagtt tccagtatct
    11221 ttttaattgc ttacctaatt gatagtgttt ttgttctttg ctttttaata gttggttcgt
    11281 ttctttgatt cgatgattgc gaaaggtacg accaatatgt tggacgatgt gaaaccggtc
    11341 aataatcagc tgtgcttttg gaaacagctt tttaacgagc gatacataag gagcgtacat
    11401 atcaacacga tccattcgac cgcttcacga atttctcgtg aaaaatgact aaaataacgt
    11461 tttaaaaagg cagttgtcgg ttctcgacaa tgtccaataa gcgctgtgtt tgtccatcca
    11521 tcatgatgaa actcatagca cctgaaacac cccgaactga tttgaattca tcaaaacaaa
    11581 gtaccttagg taacggtgtc cgaaaaggat tcaacggacg ataaaatcgc ttcataatac
    11641 ggtaaacaga agagaccgat agatttttct gagcggcgat ctctgtcatt gaggtatttt
    11701 tttcagacga gtcacgacag accagcggac tttctcactg atgaaacaat gtttttcgca
    11761 acagaagtat ctgcgacaaa ggtccgctga caagctttgc atttgaagcg ttgctttttc
    11821 aattcgaggt aggtacggta ttcagaaaca tcgttcatta acaaccggac ggttgttgta
    11881 ccccaacgca caatatctga agcaatctgg tgtttacagt ggatgcattc ttgggctgta
    11941 taaatcaagt ttccacgata aatatgacag atttgccctt tgtatttttc ttttgtgaga
    12001 caattttcgt taaaagtaac tgataagtct agaatatcta atgtttcttt gataaggtga
    12061 gtgtaagaca tcttgattcc tccttttggg ttggttcgcc aaattaattc taaaggattt
    12121 caaggtgtct tttctatatg ttttggaaaa taaaaaagat gctggtgtca tccaccaaca
    12181 tcaaaaagta tagagcctct tttctgaagt acatccgcaa ctgtccatac tctgatgttt
    12241 tatatctttt ctaaaagttc gctagataga gttctatatt agagatgtaa agagttttgg
    12301 tgaagaggtt tgtgagtatg gcttttataa ccagggtgca atgagaagca ctaacagcag
    12361 ctagcttaag aacgcatagg atatactttt tatggaagtc acagaggagg aataaaattt
    12421 gaacaggatt aacagagtaa cctctattct tattcagctg caatcaaaaa aaataattcc
    12481 tgccaaagaa attgcacagc gatttaatat aagcttaagg acagtttaca gagatatccg
    12541 gacacttgaa gaagccggaa taccaattgg atctgaggcc ggaaaaggat attttcttgt
    12601 agagggcttc ctacttccgc cggtaatgtt tacagcggcg gaagtgggtg cattgattac
    12661 agcagggaaa tttttaaatt gccatggaga tgaatcattt ataaaggatt ttgattcagc
    12721 tatgtataaa atcaaatcta ttttgaagca tggtgaaaaa aactatgcac aggagttgga
    12781 gaacagtatt aacgtgtaca gcacatctgg acagaaaaat acattggcgg ataacgttat
    12841 tgcagcaatt cagactgcaa tctgcaataa aagggtaata tcaattcaat atcctgcatc
    12901 aggagggcaa gaaccggaaa gcagaatgat agagccggtt ctgttgcaaa gttttaaata
    12961 aagaataaaa tcccttacgg tatctatgat ttaagctggg attcccaata ataccttgat
    13021 ttcagtacag accgaaaacc cgaagagagt gccttctttt cgggttttct tatataatcc
    13081 tcgaatggct tccatgcctt taatcgtggt agaggcagtg cgtaaacttc gatagaattt
    13141 attgcgtctc tttactggac gatggtcttg ttcaatcaaa ttattcaggt atttaatggt
    13201 acgatgttct gtcccttgat aaaagccgta ttcttttagt ttcttaaagg cacttgtaat
    13261 agagggggct ttatctgtga ctacaacctt cggttcatca aactgcttca ctaaccgctt
    13321 aagaaaagca taggctgctt gtgtgtcccg ttttttacgt aaccaaatat ccaaggttaa
    13381 accatctgca tcgatggctc gatacaaata atgccatttt cctttaattt tgatgtacgt
    13441 ttcatccatt ttccatgaat aaaaggattt tttatttttc tttttccaaa tttgatagag
    13501 tagtttgcca tattcttgca cccaacgata aatcgtcgta tgagaaacgt taatgccacg
    13561 atcatataag atttcttgaa cttcacgata gctaaggtta taacgaagat agtagcccac
    13621 ggctacaata atcacatcct gctgaaattg ctttccttta aaatgattca tcgtcattcc
    13681 tcctgctatc tttttctatt attctacctt atttgatagt agatttaaaa ctttgcaaca
    13741 gaaccctata gagaagaata aattcatttc tactgacgta aatttgcgta aaggaatcgt
    13801 atttaattca tggtggtatt tcacaatttc atttgccata aaatcctcct tcaagattaa
    13861 ctacttaaca aaattataaa gagctttcta ataggggtca agcccctaat taaagacccc
    13921 taaaaacaga caaaaagacc cccaaaaaca aacaaaaaga cccctaaaaa cagacaaaaa
    13981 gacccctaaa aacagacaaa aagaccccca aaagattctg cacaccttgg gagagtaagc
    14041 atacagccga cggtaaagag gtttaaaaag aggtttaaaa agagattata aaagaggaga
    14101 ggggcaaaat ttcccgccta aaaattttct gcttttttag ccaaacaggt tcgcgaattt
    14161 tactaaactg ggaaacttgc tccctctggt cgctaaaaag gtgtgaggga aaaacaccct
    14221 cacattgtac ctgcgcagtc gcctaaaggc tcctttgcta aaaacgttgt ttaaagagat
    14281 ttttttagag gctctgcgcg ctcgtttaag ccgttttaag acagtttagt atggataacc
    14341 cttatcttgt tcttaaagca ccttacaggc ggtcagggca agccctaaca acccttaaag
    14401 agcataaaac catcctaaaa ttcgatttaa tctgtcttat ctatgttctt gtatatttta
    14461 tataccttgg gtagtaaaac gtctgaaaac gcaaataaga gcgtatgaaa caaaacaata
    14521 agcaaccgat tcagcagaat tccggaggag ccattttcgt acgttagcaa aaaagtgctg
    14581 ttgctaaaag ctgcttgcgg tgcggagcga acaaggtctc ctagagcgag acgtgtacaa
    14641 acaagcttac aaattcgtga aaggcaccgg ttttgcgcca tttccaagca aaaaaaggtc
    14701 tatcgagcaa gctcgataga ccgatcgcat ttagcccccc gcattctaac agggggggaa
    14761 taatgtgaaa aattatggta gtaatgcttg atatataggc atttcttttg gttgcacact
    14821 taaaaaaaat cacgattttg acaactaaat ttttaaataa aaaagcttta cagtttaatt
    14881 caaatgtgtt ttaatatatc tatcagtact tgccacgcct ctgatttaat atcatgcgca
    14941 ttatggtagg gctttttttt tatatttttt taagaaagaa gattcttatg aagacatcaa
    15001 atagaaaata taaagttaaa acagttaatc atagaattcc acctaaaaag gcattatgtg
    15061 taattaataa ttccaaagta attaatcaag agttaaaacc atatttatcc gagcaagaaa
    15121 tgataaaaaa aataagtaaa gatatttttt taacaaattc cgatacaatt ttattagaaa
    15181 agtttttaaa gaaaaatagt tattttcgat ttagtattta tgttaaatta atgaaaaata
    15241 tagataaagt tactattcta gatgttattg aaacgtacaa attagattca ttcattcgta
    15301 atcaattgca ttattttgtg aatcaaatag aaattttttg gaaaaaatct ctttcagata
    15361 atatgtgcgt ttcttatgaa gaaactagca tatttccgaa gaatcagtgt tatttggata
    15421 aaaatattta ttcagatttg aaatgggctg aagatataat tggtcatttt aatagttttt
    15481 tttattcaaa tcaaagtccc acttttaaac atcatcatat aaaaaaaaat cattgtttac
    15541 caatatgggc tttatttgaa gaaataacat ttggtagttt aacaacattt attaatcaac
    15601 ttaatacaga gtattataat aattgggtca tgagctgtta tgataatcct aaatacaaaa
    15661 aagctatacg aagttgggca aacgtaatta gagcttatag aaataagata gctcatcatt
    15721 caagaatata tgcatttaaa gttactgacg ctccaacaat cataaaaaat gattccaaaa
    15781 gttattttcc tgaaaataac ttaaaagaaa cccaaaagtt atatttgtat ggaggattat
    15841 acgttataaa acatctgtta atatatgaag atagcatgac acaaacttta tggaataaat
    15901 ttctaataga tttagaaaaa aagatcgata aaatcccttc cttagaaaaa tccaattatg
    15961 gttttccgga aaattggaga aacaagttaa aaataatgat tgtttaattg ttatttaaat
    16021 tgttagtaga cataatgtac atactaccaa gtagcccctg gatcaaccga tccaggggaa
    16081 gactttgtga ttttcaattg gtctatctaa aacatctttt taaaagcttg attcttcgct
    16141 gttggctttt ttcgattctt tgtgaatatt cagtgattat ttttttacta cttgttattt
    16201 tccgagggat ttgttaaaag tttaatagcg tttctcagta agggacgtcg ttttttcatt
    16261 ttcctatgta tggactgctc gaacgagcag ccttttttta ttccagggaa cgtcctattc
    16321 tttgagtttc catgctattg aataaccggg acttagggat tagggcagcg ccccaaaatg
    16381 aaaaaagaaa aatccgcttc tgcgaattct tctttttttt cgcaagttgg taccaacttg
    16441 caaatcttgc tggaagaccg atccctaaaa agaaatcgag gaattttttt gtttttcggt
    16501 ttcttttttt atctttttag aaagtttgtt gggtcaaaat ttccagaagt aaaggtttga
    16561 ttggtttctt tttgacgatt tttgggttga tttcgtcggg aaggattgag ttgattttca
    16621 attttttctt tcacttcttg atatacttta gaatttgtac cgataagaac accagtatct
    16681 tttagatata aatcagcaaa ttctgccatg atttctgtca tgatagaaat ttcttttccc
    16741 atggcattga gttttgcttg gttactggtt gtggttgtat tggtatcagg ttcataactc
    16801 atacataaaa agcgaatggc ttctgaataa ttgttaacgt ctggattttt ttcgatgatg
    16861 gaatctaaaa cgtcaacgtg actgggataa agggttacgt gtttttgaac agaagttttt
    16921 ctcatgttat attcctccga taagtgtttc aatgagttgg ttgtttgtgt gaacatagtc
    16981 atttagtatg ttcgtatttt ctgcttgaat ggcaataaat ttttcgaata ataaatcgaa
    17041 ttgatctttt ttgtaattca taagttcgtg gtcaaaatcg ttttcgatta aaatttttag
    17101 gtattgattt cgactccatt ttttgcccgt tttggttgtt agttcctgac aacgtttatc
    17161 tattcttgta ataattttgg gattgatatt tcgaactaaa atgtccatgg aaattttcct
    17221 ttcgtatcag tgtataattt atgtatatca tacaaatata gtatttgtat agctattttt
    17281 cgccaaaaca ctatacatag cctagccaca atggcaaaaa agtgatagca aatttttttc
    17341 tgagaaacgt gataggcaca gcttatctag cacctttcgt aagaaagtga taccacgttt
    17401 ccttatgctc tttcaaaatt cagaaaaatc agctgtaaaa cgagtgcagt ccgagtaaga
    17461 ttcaacgaaa aaacggggat tggggcgcca ccaaaatatc gcaacatggg cccatgttgc
    17521 tctgctcgca aaagaaaaaa gaagaataaa accagcaatt tttattaatt taaattgctg
    17581 gttttattgc cagaattgcc accatttttt ctccgtcttt gattgttttt ctatcgattc
    17641 tgtttcttca gaaagagtcg ttgatttatt ttccgaagat tcttccgtat aagtcaactg
    17701 tagttgttcc tgcagtttct cgatttgttg gttggcttgc agggtgagtt gttgttgttg
    17761 gtcgagtaat ttttgcattt gttttatttg ctcgtctttt tcttgtagtt gcatatcttt
    17821 ttgatttaac tgttgttcta ggagagaaag gacttctaat tcgggaactt ggttggcgtt
    17881 tttgtggttt tcggttttag ttttttcgcc aactagttgt tgatttgagt tttcgttttc
    17941 gttaaaaaac attgatttta tagccttttg tccggtttca ttaatcacaa acttgtttcc
    18001 gattttcgaa aaccaaagtt ttcgattttc gtcagaaact tttttgttaa ttgctgtttt
    18061 actaactcct aattcttcag caagttcttt gattgttttt tctgtcataa aatctaaaaa
    18121 cccctcaatc tttgaataag ttttgaagat tgtctaataa gtcttttttt agttctgaag
    18181 gaatatcgga atttatctct gatttttgtg cattattttc tttattttgg gtattttgtt
    18241 ctctttctaa cttttctaac tgttgtaaaa gttccaattt tcgcttttgt tctttgattt
    18301 tttcttgtaa tgaagtaggt gctttttcag attgaacttg ttggttagct agttctaatg
    18361 ctttgttttg ttcttctttt gttggggcat gtttgttaaa gtcgtctgat ttttttatct
    18421 caggtttaaa tgtaaattga tagccaatga caggctttcc ccgtcctttt ccgtatctct
    18481 tttggattgt cagacctttg aagattgcgg ttagttcttg gcgaataggc tttataattt
    18541 ttttatttat atcactttct ctataacttt tagggatatc aagtaattca tgaaagtctt
    18601 cttttgaaaa ataggcaatt cctttggttc tgtattgttt taataatcta aacatggttt
    18661 tggaataact gctttctaat tcattgaatt gttggagaga atatcgaacc cattcttcaa
    18721 gattattaag taagggtaag gctttctcat ggacttgtat ttcagcaaaa ggaatatcag
    18781 cttttccatc gattttaaat tgattaaata aaacaaatcg ttcacgttgc aaaccgtcag
    18841 cacttcttct accaaaacgt aaatccatta atttgtcata cgttgtttct aaatcatcta
    18901 tgaatcgaac atttgcagtt gctttataat tgcttaaatc ttttaattgt tcgaatgtaa
    18961 attgtacttt tttatcgcct acgtcacgca ttctagatac tatagagggt tctgttgcaa
    19021 agttttaaat aaagaataaa atcccttacg gtatctatga tttaagctgg gattcccaat
    19081 aataccttga tttcagtaca gaccgaaaac ccgaagagag tgccttcttt tcgggttttc
    19141 ttatataatc ctcgaatggc ttccatgcct ttaatcgtgg tagaggcagt gcgtaaactt
    19201 cgatagaatt tattgcgtct ctttactgga cgatggtctt gttcaatcaa attattcagg
    19261 tatttaatgg tacgatgttc tgtcccttga taaaagccgt attcttttag tttcttaaag
    19321 gcacttgtaa tagagggggc tttatctgtg actacaacct tcggttcatc aaactgcttc
    19381 actaaccgct taagaaaagc ataggctgct tgtgtgtccc gttttttacg taaccaaata
    19441 tccaaggtta aaccatctgc atcgatggct cgatacaaat aatgccattt tcctttaatt
    19501 ttgatgtacg tttcatccat tttccatgaa taaaaggatt ttttattttt ctttttccaa
    19561 atttgataga gtagtttgcc atattcttgc acccaacgat aaatcgtcgt atgagaaacg
    19621 ttaatgccac gatcatataa gatttcttga acttcacgat agctaaggtt ataacgaaga
    19681 tagtagccca cggctacaat aatcacatcc tgctgaaatt gctttccttt aaaatgattc
    19741 atcgtcattc ctcctgctat ctttttctat tattctacct tatttgatag tagatttaaa
    19801 actttgcaac agaaccaatt atgcggtaaa gctatataaa gaaggaaata tgactgtaaa
    19861 tcaaatttgt gaaattacta atgtatctag ggcttcatta tacaggaaat tatcagaagt
    19921 gaataattag ccattctgta ttccgctaat gggcaatatt tttaaagaag aaaaggaaac
    19981 tataaaatat taacagcctc ctagcgatgc cgaaaagccc tttgataaaa aaagaatcat
    20041 catcttaaga aattcttagt catttattat gtaaatgctt ataaattcgg ccctataatc
    20101 tgataaatta ttaagggcaa acttatgtga aagggtgata actatgagcg ataaaatact
    20161 tattgtggat gatgaacatg aaattgccga tttggttgaa ttatacttaa aaaacgagaa
    20221 ttatacggtt ttcaaatact ataccgccaa agaagcattg gaatgtatag acaagtctga
    20281 gattgacctt gccatattgg acatcatgct tcccggcaca agcggcctta ctatctgtca
    20341 aaaaataagg gacaagcaca cctatccgat tatcatgctg accgggaaag atacagaggt
    20401 agataaaatt acagggttaa caatcggcgc ggatgattat ataacgaagc cctttcgccc
    20461 actggagtta attgctcggg taaaggccca gttgcgccga tacaaaaaat tcagtggagt
    20521 aaaggagcag aacgaaaatg ttatcgtcca ctccggcctt gtcattaatg ttaacaccca
    20581 tgagtgttat ctgaacgaga agcagttatc ccttactccc accgagtttt caatactgcg
    20641 aatcctctgt gaaaacaagg ggaatgtggt tagctccgag ctgctatttc atgagatatg
    20701 gggcgacgaa tatttcagca agagcaacaa caccatcacc gtgcatatcc ggcatttgcg
    20761 cgaaaaaatg aacgacacca ttgataatcc gaaatatata aaaacggtat ggggggttgg
    20821 ttataaaatt gaaaaataaa aaaaacgact attccaaact agaacgaaaa ctttacatgt
    20881 atatcgttgc aattgttgtg gtagcaattg tattcgtgtt gtatattcgt tcaatgatcc
    20941 gagggaaact tggggattgg atcttaagta ttttggaaaa caaatatgac ttaaatcacc
    21001 tggacgcgat gaaattatat caatattcca tacggaacaa tatagatatc tttatttatg
    21061 tggcgattgt cattagtatt cttattctat gtcgcgtcat gctttcaaaa ttcgcaaaat
    21121 actttgacga gataaatacc ggcattgatg tacttattca gaacgaagat aaacaaattg
    21181 agctttctgc ggaaatggat gttatggaac aaaagctcaa cacattaaaa cggactctgg
    21241 aaaagcgaga gcaggatgca aagctggccg aacaaagaaa aaatgacgtt gttatgtact
    21301 tggcgcacga tattaaaacg ccccttacat ccattatcgg ttatttgagc ctgcttgacg
    21361 aggctccaga catgccggta gatcaaaagg caaagtatgt gcatatcacg ttggacaaag
    21421 cgtatcgact cgaacagcta atcgacgagt tttttgagat tacacggtat aacctacaaa
    21481 cgataacgct aacaaaaacg cacatagacc tatactatat gctggtgcag atgaccgatg
    21541 aattttatcc tcagctttcc gcacatggaa aacaggcggt tattcacgcc cccgaggatc
    21601 tgaccgtgtc cggcgaccct gataaactcg cgagagtctt taacaacatt ttgaaaaacg
    21661 ccgctgcata cagtgaggat aacagcatca ttgacattac cgcgggcctc tccggggatg
    21721 tggtgtcaat cgaattcaag aacactggaa gcatcccaaa agataagcta gctgccatat
    21781 ttgaaaagtt ctataggctg gacaatgctc gttcttccga tacgggtggc gcgggacttg
    21841 gattggcgat tgcaaaagaa attattgttc agcatggagg gcagatttac gcggaaagca
    21901 atgataacta tacgacgttt agggtagagc ttccagcgat gccagacttg gttgataaaa
    21961 ggaggtccta agagatgtat ataattttgg ctctttgtca aatgatgttg gtaaagagaa
    22021 atcttagaat aattggagat caagtggatc agttcctctt gatctttttt agttgaaaat
    22081 caatgcgttg ccatgacgaa tcatgatgcg caatttgaaa ttataaaagc tacgaaagcc
    22141 atatgcattt cgttttaaca ctttgatatg gttgttcaga cattcaagtg ggccatttga
    22201 ataactttgt tgtaaagcat ttttgatttg tggcagaaat ttctggaacg ttctcaaggt
    22261 cgtctgatag ccttcgggaa gcatgatatt attggtaagt agttcttcaa acgatacgta
    22321 gtctcgttcc tttacagcgt aaagaaagtc ttgatataac tgatagccta cacgcaaagc
    22381 agggctccct ttcagtaagc gatccacaat atcggtctct gttaaatgag ctttgaagcc
    22441 aggtcgccaa aggcgtcgag tataatcaag cttgcgttca tctttttgaa gaagtttcca
    22501 gtatcttttt aattgcttac ctaattgata gtgtttttgt tctttgcttt ttaatagttg
    22561 gttcgtttct ttgattcgat gattgcgaaa ggtacgacca atatgttgga cgatgtgaaa
    22621 ccggtcaata atcagctgtg cttttggaaa cagcttttta acgagcgata cataaggagc
    22681 gtacatatca atcacgatcc attcgaccgc ttcacgaatt tctcgtgaaa aatgactaaa
    22741 ataacgtttt aaaaaaggca gttgtcggtt ctcgacaatg tccaataagc gctgtgtttg
    22801 tccatccatc atgatgaaac tcatagcacc tgaaacaccc cgaactgatt tgaattcatc
    22861 aaaacaaagt accttaggta acggtgtccg aaaaggattc aacggacgat aaaatcgctt
    22921 cataatacgg taaacagaag agaccgatag atttttctga gcggcgatct ctgtcattga
    22981 ggtatttttt ttcagacgag tcacgacaga ccagcggact ttctcactga tgaaacaatg
    23041 ttttttcgca acagaagtat ctgcgacaaa ggtccgctga caagctttgc atttgaagcg
    23101 ttgctttttc aattcgaggt aggtacggta ttcagaaaca tcgttcatta acaaccggac
    23161 ggttgttgta ccccaacgca caatatctga agcaatctgg tgtttacagt ggatgcattc
    23221 ttgggctgta taaatcaagt ttccacgata aatatgacag atttgccctt tgtatttttc
    23281 ttttgtgaga caattttcgt taaaagtaac tgataagtct agaatatcta atgtttcttt
    23341 gataaggtga gtgtaagaca tcttgattcc tccttttggg ttggttcgcc aaattaattc
    23401 taaaggattt caaggtgtct tttctatatg ttttggaaaa taaaaaagat gctggtgtca
    23461 tccaccaaca tcaaaaagta tagagccata attttttagg aaaatctcaa ggttatcttt
    23521 actttttctt aggaaattaa caatttaata ttaagaaacg gctcgttctt acacggtaga
    23581 cttaataccg taagaacgag ccgttttcgt tcttcagaga aagatttgac aagattacca
    23641 ttggcatccc cgttttattt ggtgcctttc acagaaaggg ttggtcttaa ttatgaataa
    23701 catcggcatt actgtttatg gatgtgagca ggatgaggca gatgcattcc atgctctttc
    23761 gcctcgcttt ggcgttatgg caacgataat taacgccaac gtgtcggaat ccaacgccaa
    23821 atccgcgcct ttcaatcaat gtatcagtgt gggacataaa tcagagattt ccgcctctat
    23881 tcttcttgcg ctgaagagag ccggtgtgaa atatatttct acccgaagca tcggctgcaa
    23941 tcatatagat acaactgctg ctaagagaat gggcatcact gtcgacaatg tggcgtactc
    24001 gccggatagc gttgccgatt atactatgat gctaattctt atggcagtac gcaacgtaaa
    24061 atcgattgtg cgctctgtgg aaaaacatga tttcaggttg gacagcgacc gtggcaaggt
    24121 actcagcgac atgacagttg gtgtggtggg aacgggccag ataggcaaag cggttattga
    24181 gcggctgcga ggatttggat gtaaagtgtt ggcttatagt cgcagccgaa gtatagaggt
    24241 aaactatgta ccgtttgatg agttgctgca aaatagcgat atcgttacgc ttcatgtgcc
    24301 gctcaatacg gatacgcact atattatcag ccacgaacaa atacagagaa tgaagcaagg
    24361 agcatttctt atcaatactg ggcgcggtcc acttgtagat acctatgagt tggttaaagc
    24421 attagaaaac gggaaactgg gcggtgccgc attggatgta ttggaaggag aggaagagtt
    24481 tttctactct gattgcaccc aaaaaccaat tgataatcaa tttttactta aacttcaaag
    24541 aatgcctaac gtgataatca caccgcatac ggcctattat accgagcaag cgttgcgtga
    24601 taccgttgaa aaaaccatta aaaactgttt ggattttgaa aggagacagg agcatgaata
    24661 gaataaaagt tgcaatactg tttgggggtt gctcagagga gcatgacgta tcggtaaaat
    24721 ctgcaataga gatagccgct aacattaata aagaaaaata cgagccgtta tacattggaa
    24781 ttacgaaatc tggtgtatgg aaaatgtgcg aaaaaccttg cgcggaatgg gaaaacgaca
    24841 attgctattc agctgtactc tcgccggata aaaaaatgca cggattactt gttaaaaaga
    24901 accatgaata tgaaatcaac catgttgatg tagcattttc agctttgcat ggcaagtcag
    24961 gtgaagatgg atccatacaa ggtctgtttg aattgtccgg tatccctttt gtaggctgcg
    25021 atattcaaag ctcagcaatt tgtatggaca aatcgttgac atacatcgtt gcgaaaaatg
    25081 ctgggatagc tactcccgcc ttttgggtta ttaataaaga tgataggccg gtggcagcta
    25141 cgtttaccta tcctgttttt gttaagccgg cgcgttcagg ctcatccttc ggtgtgaaaa
    25201 aagtcaatag cgcggacgaa ttggactacg caattgaatc ggcaagacaa tatgacagca
    25261 aaatcttaat tgagcaggct gtttcgggct gtgaggtcgg ttgtgcggta ttgggaaaca
    25321 gtgccgcgtt agctgttggc gaggtggacc aaatcaggct gcagtacgga atctttcgta
    25381 ttcatcagga agtcgagccg gaaaaaggct ctgaaaacgc agttataacc gttcccgcag
    25441 acctttcagc agaggagcga ggacggatac aggaaacggc aaaaaaaata tataaagcgc
    25501 tcggctgtag aggtctagcc cgtgtggata tgtttttaca agataacggc cgcattgtac
    25561 tgaacgaagt caatactctg cccggtttca cgtcatacag tcgttatccc cgtatgatgg
    25621 ccgctgcagg tattgcactt cccgaactga ttgaccgctt gatcgtatta gcgttaaagg
    25681 ggtgataagc atggaaatag gatttacttt tttagatgaa atagtacacg gtgttcgttg
    25741 ggacgctaaa tatgccactt gggataattt caccggaaaa ccggttgacg gttatgaagt
    25801 aaatcgcatt gtagggacat acgagttggc tgaatcgctt ttgaaggcaa aagaactggc
    25861 tgctacccaa gggtacggat tgcttctatg ggacggttac cgtcctaatc gtgctgtaaa
    25921 ctgttttatg caatgggctg cacagccgga aaataacctg acaaaggaaa gttattatcc
    25981 caatattgac cgaactgaga tgatttcaaa aggatacgtg gcttcaaaat caagccatag
    26041 ccgcggcagt gccattgatc ttacgcttta tcgattagac acgggtgagc ttgtaccaat
    26101 ggggagccga tttgatttta tggatgaacg ctctcatcat gcggcaaatg gaatatcatg
    26161 caatgaagcg caaaatcgca gacgtttgcg ctccatcatg gaaaacagtg ggtttgaagc
    26221 atatagcctc gaatggtggc actatgtatt aagagacgaa ccatacccca atagctattt
    26281 tgatttcccc gttaaataaa cttttaaccg ttgcacggac aaactatata agctaactct
    26341 ttcggcagga aacccgacgt atgtaactgg ttcttaggga atttatatat agtagatagt
    26401 attgaagatg taaggcagag cgatattgcg gtcattatct gcgtgcgctg cggcaagata
    26461 gcctgataat aagactgatc gcatagaggg gtggtatttc acaccgccca ttgtcaacag
    26521 gcagttcagc ctcgttaaat tcagcatggg tatcacttat gaaaattcat ctacattggt
    26581 gataatagta aatccagtag ggcgaaataa ttgactgtaa tttacggggc aaaacggcac
    26641 aatctcaaac gagattgtgc cgtttaaggg gaagattcta gaaatatttc atacttccaa
    26701 ctatatagtt aaggaggaga ctgaaaatga agaagttgtt ttttttattg ttattgttat
    26761 tcttaatata cttaggttat gactacgtta atgaagcact gttttctcag gaaaaagtcg
    26821 aatttcaaaa ttatgatcaa aatcccaaag aacatttaga aaatagtggg acttctgaaa
    26881 atacccaaga gaaaacaatt acagaagaac aggtttatca aggaaatctg ctattaatca
    26941 atagtaaata tcctgttcgc caagaaagtg tgaagtcaga tatcgtgaat ttatctaaac
    27001 atgacgaatt aataaatgga tacgggttgc ttgatagtaa tatttatatg tcaaaagaaa
    27061 tagcacaaaa attttcagag atggtcaatg atgctgtaaa gggtggcgtt agtcatttta
    27121 ttattaatag tggctatcga gactttgatg agcaaagtgt gctttaccaa gaaatggggg
    27181 ctgagtatgc cttaccagca ggttatagtg agcataattc aggtttatca ctagatgtag
    27241 gatcaagctt gacgaaaatg gaacgagccc ctgaaggaaa gtggatagaa gaaaatgctt
    27301 ggaaatacgg gttcatttta cgttatccag aggacaaaac agagttaaca ggaattcaat
    27361 atgaactatg gcatattcgc tatgttggtt taccacatag tgcgattatg aaagaaaaga
    27421 atttcgttct cgaggaatat atggattacc taaaagaaga aaaaaccatt tctgttagtg
    27481 taaatgggga aaaatatgag atcttttatt atcctgttac taaaaatacc accattcatg
    27541 tgccgactaa tcttcgttat gagatatcag gaaacaatat agacggtgta attgtgacag
    27601 tgtttcccgg atcaacacat actaattcaa ggaggtaagg atggcggaat gaaaccaacg
    27661 aaattaatga acagcattat tgtactagca cttttggggt aacgttagct ttttaattta
    27721 aaacccacgt taactaggac attgctatac taatgataca acttaaacaa aagaattaga
    27781 ggaaattata ttgggaaaaa tattatctag aggattgcta gctttatatt tagtgacact
    27841 aatctggtta gtgttattca aattacaata caatatttta tcagtattta attatcatca
    27901 aagaagtctt aacttgactc catttactgc tactgggaat ttcagagaga tgatagataa
    27961 tgttataatc tttattccat ttggcttgct tttgaatgtc aattttaaag aaatcggatt
    28021 tttacctaag tttgcttttg tactggtttt aagtcttact tttgaaataa ttcaatttat
    28081 cttcgctatt ggagcgacag acataacaga tgtaattaca aatactgttg gaggctttct
    28141 tggactgaaa ttatatggtt taagcaataa gcatatgaat caaaaaaaat tagacagagt
    28201 tattattttt gtaggtatac ttttgctcgt attattgctc gtttaccgta cccatttaag
    28261 aataaattac gtgtaagatg tctaaatcaa gcaatctgat ctttcataca cataaagata
    28321 ttgaatgaat tggattagat ggaaaacggg atgtggggaa actcgcccgt aggtgtgaag
    28381 tgaggggaaa accggtgata aagtaaaaag cttacctaac actatagtaa caaagaaagc
    28441 ccaattatca attttagtgc tgaggaattg gtctctttaa taaatttcct taacgttgta
    28501 aatccgcatt ttcctgacgg tacccccaaa ctaagatttc atagatagat tttctgataa
    28561 ctttaaaaaa cacgaatagc ggaaaggatg tcttcattcg ctaaagagta ataaactact
    28621 tttccatctt gacgtgattt tgccattcca tgttttttta aaaaacgtaa atggtgtgac
    28681 gttgtagcga cactagcagt aagtatttct gctaaatcac agacgcacat ttccttatag
    28741 gtttctaaag catagaaaat tttaattcta gaaaaatcgc tgaaacattt ccctaacaca
    28801 agtaagtttg aaaaatcttt ttgatccaat ttatttttta ttccatttac tttttcttta
    28861 tgtacgacag tcacttggca aacttttttc attcatctca cctcacattc aaacgattat
    28921 ttgaatgaag tatacctatt tgatcactct tttgtcaatc taccttaatt ccaatacact
    28981 attataagca atttcatgta ttgaagtaaa cttacttgca agtgcgtttt tgattccaag
    29041 ttaaaaacat attattattc tacataattt cctaatcaaa taaaactcct ttgaaaattg
    29101 ttctaaagga gttttattat tttgtatttc tactaaaaat agcgtacaat gtaattacta
    29161 agtaattacg aaatgtaaaa taatggagga aataatatga ttacaaaaac aagaaaacaa
    29221 ggaaattcta ttatgttaac ggtccctaaa gaattcgatg tgcccaatgg tgttgaagta
    29281 gaagctaagc ttgtagagaa tggtatcctt tatgagtttg tagagcctaa aaaagaattt
    29341 tttgatttta gtgaagatat tttggctgat attctttcag aaggttatag caaacaagag
    29401 atcttaaaag aatttagaaa tagaaaaaat gcgttaactt ctgcatttaa atctattgct
    29461 gaagatactg ttgcaaattc taaaccgatg acaaaagagg agttggcagc agaaattggc
    29521 ttatgagatt ctaccttcta aacacgtaat aaagtatcta aaaaaattaa aagagaaaac
    29581 attaaaagaa caatttttaa cgataattta tgatgagata gcagttcgtc ctcattcggg
    29641 agaacaaaaa acgggtgatt tatcaggaat ttgggctatt ggattcaagt atgcaggtac
    29701 gacatatcgc gttgcatatg aaattaaaga taatgcagtg atacctatct tactatgtgg
    29761 aacgcatgaa aatttttatg aacaattaaa aaagattagg taagaaccca atgtttcaac
    29821 ttgagaggat agacgacact ttaaaagata atttttaaca gctgagagtt gtaataccct
    29881 ataattttaa accactaacc tatatattta tgaaaaatag aaaaaattaa aacgcatttt
    29941 aagcctcttt caaattaaaa gcttcatcct tatgcacaaa gagggcttaa aatgcgttat
    30001 tttatattgt tttttagtaa taataaaaaa atcactctaa ttctcccata aatattatag
    30061 attcctaaag attaaaatag attattccct attgtctttt aagtagcggt agagtgttgc
    30121 cttgctaata ccagtcattt ccgtaatttc ttttacgcta taaacctgac ttttatacaa
    30181 ttttactgct cgatcaacat ctttctggtt cactcgtgga cggccacctt tacgacctct
    30241 cgcacgtgca cttttcaaac cttctttggt acgttcaaca attaaatcac gttcgaactg
    30301 actaaatgct tggaagacag tcatcattaa gcgtccgtga ggcgtgctgg tatcgaagtt
    30361 ttctttcaag ctcaccagct taacatggtg ttcttcaaaa taggtaacaa ggtcaatcaa
    30421 atcctttgta ctacgaccca atcgagaaaa actttctaca attaccgtat ctcccggacg
    30481 aattttatct tttaaacgat ttagttgggg acgaaccgct ttggttcccg tcattttctc
    30541 agttaggatt tcattacaat tttgttcatt gagtaagtct aattgacgat ttagttcttg
    30601 tgaacgtgta ctcactcggg cataaccata aatgtatcca ctcatgcttt tcttcctttc
    30661 gtactttaat tctggcttga ttgtatcata aaagggagtt atagatacat agttaatgca
    30721 acaagttatg atacaaaata tgacctcttt tatttaataa aagaggtcat ttcattttgt
    30781 ctcataatcg attgtttttg atacgagtgt gtatacgaaa taaacaaaaa aatcttaagt
    30841 aaatttctag atacctaatt taatcctaac tagtgtatcc taaagttaat aacgagttta
    30901 tcacaatgaa aattataaaa tgctcccata ttagatataa catgcaatat ttgaattaga
    30961 actacaaaat ttattcgttt tataaagtaa ataatgttga gatactaagg aatagaatat
    31021 tataaggaat tgagctgaat gtattggata aaaaaagaat aactttatta gagatggact
    31081 ataaaaatgc tcgtaatttt cttctgaagt ctgaaagcta tttgaatgct cagctaccag
    31141 aatatattag ttttgacgaa actttaaaat ctgctaaaaa agttttaact tcgccgtttg
    31201 tataattaag cgagacaaat aaaaaagcca tttatgttac actcaaattg taatacccgc
    31261 taaagcatac aaggagagtg aacataaatg acttataccc atcttacacc aaacgagctt
    31321 gtaatgatag aagcatattt tcatcaagaa actccggttg ctatcgttgc gaagcagctt
    31381 aaacgtggac gccaaacaat ttacaatgtc tataactttc tcaaatgtgg tggaacagca
    31441 cttgaatact ttgaacaata caaagaaaat aagcgacgtt gtgggagaac cgaaatcatt
    31501 tttcctgctg aggaaaaaga atacattgaa aaaagatcaa ctgaaggttg gaccccagac
    31561 gtcattattg gccgtgcaga gcgaaccttc tcttgttcag taagtaccct ctatcgccgg
    31621 tttaagacgg gagaattcaa tgttttacat ttaccgatgc aaggaaaacg aaaaccaaat
    31681 ggttataagg aaaaacgtgg aaaacaggca ttcaaaagaa atatttctga acgtaaaaaa
    31741 gattatgtcg ttttcgaaga agaatttgga catttagagg gtgatacgat tgtcggcatc
    31801 caccataaaa gtgccgtcat cacactcgtt gagcgacttt caaaagccat tatcgccttg
    31861 aaaccagaag gccgtaaggc agttgatatt gaaaattcga ttaatgaatg gcttcaatcc
    31921 gtacccaaaa atcttttcaa atcaattacc tttgattgtg gaaaagaatt ctctaattgg
    31981 aaaagtatta gtaatacgaa tgatattgat atttatttcg cagacccagg aacgccttcc
    32041 caacggggat taaatgaaca ttcaaacgga ctcctccgaa aagatggact accaaaagaa
    32101 atggacttca accaagtcaa tcaaggattc atctcatccg ttgcgtccaa aagaaaccat
    32161 atccctagaa aatcactaaa ttaccaaaca ccattagaag tttttttgag ttacgtaaat
    32221 ggaaagtttt gtctcgctta atttgacaaa taatacttca aaaaaaaacc aaccgaaaga
    32281 tataaaagat attgtagata cacgaatgta taaagaacgt gatgacttaa actatacgct
    32341 tattatcaat aaagatggaa actattcatg gcgtcctctc gttctactac atcctattct
    32401 atatgtagat ttggttaatt gtctcactaa agaagaccat tgggaggagt taaaaaagag
    32461 gtttagtgaa tttaaaaaag ataaaaatat taactgttat tctatacctg ttgaagcttc
    32521 caaaggttca aaaaggacag atcttggtga aacaatacta aactggtggg aatattttga
    32581 acaaaaaagc ttagctcaga atattaaata ccaatattgc atgtttactg acatcgctga
    32641 ttgttatcca tcaatttata ctcactctat aacatgggcc atgtatggta aagaaaaagt
    32701 taaaaatgat gaaaataagt gttcgggctc acttggcgat aaaatagata aaaaaatatc
    32761 tggaatgcaa cacaatcaaa caaatggtat ccctcagggt tccgttctta tggattttgt
    32821 agcagagatc gttctagggt atgttgattt gagattatcg aaagaattaa aaaaattaga
    32881 aaatttaaaa gattacaaag tactcagata tagagatgat tatagaatat tttcaaataa
    32941 tcgtaatgat ttggaacaaa ttatgaaagt gttatcagaa gtcttatatg atttaaattt
    33001 taagttaaat tctagtaaaa caaaattatc agatgatatt atcatagatt ctatcaaaaa
    33061 agataagctc tattgggaag aaattaaggc aagtataaga atgaatgcca caaacttaga
    33121 tggtgataga gaaattcgtt atagtataaa tttacaaaaa catttattgg aaataaaaaa
    33181 gttagcagat aagcatccta attcaggcca attgaaaaaa gcactttctg agtttaataa
    33241 agaacgcatt attaaaatca cttcaaagcc gaacgatctt ttaccactta ttggtatcct
    33301 ggtagatatc atgataaata acccgggttc tttgccgcag tgtgtcttaa ttatagggca
    33361 gttattaaat ttcgaaaatg agagtaaggc tagagaaata gttgaaatga ttataaacaa
    33421 atatgcttta aagccaaata ctgaatttat gatgatatgg tttcaaagat tgaccaccat
    33481 ttttggagaa atgtttgata gtgttttatc atccgaattt gtatctaaaa tcaaagatcc
    33541 tgtctctaat cagatgtttt ctgtagactg gctaaatgaa gatgctaaga aatcttttta
    33601 tgaagggacc attaaagacg aagagaaata tattaaaatg agtaagaaaa tatatattac
    33661 tgaatttgat gattttaatg attatccttt ttaagtgaaa atttagaatg aatataaaaa
    33721 acattacaat ctaatttttt taaaaaaatg ttatatcgga agtaatctct tgatttctat
    33781 actataagat aagaaaacca ctatttaaca aggttattcg aaccttattt taagttactt
    33841 attatttaat gtatcgaaaa aggtgaaata ggtttgttat aataagaatt aagtaagaca
    33901 tgaattgtct aagcaaatgt agcttatcca tttcattaaa atacatatgg tgaaaaaaca
    33961 agttcaaata gtaactaatt ttttaaaaaa ctgatttata aaaaatacaa cacgaatgag
    34021 gaaaataacc aatgacagaa caaatcgaaa aaaattcaaa aagcttatat caggcactgt
    34081 ggaattccgc agatatcctg cgttcaaaaa tggacgctaa tgaatacaag agctatttac
    34141 taggcttggt cttttataaa tacttatccg acaacaggtt ctgttgcaaa gttttaaata
    34201 aagaataaaa tcccttacgg tatctatgat ttaagctggg attcccaata ataccttgat
    34261 ttcagtacag accgaaaacc cgaagagagt gccttctttt cgggttttct tatataatcc
    34321 tcgaatggct tccatgcctt taatcgtggt agaggcagtg cgtaaacttc gatagaattt
    34381 attgcgtctc tttactggac gatggtcttg ttcaatcaaa ttattcaggt atttaatggt
    34441 acgatgttct gtcccttgat aaaagccgta ttcttttagt ttcttaaagg cacttgtaat
    34501 agagggggct ttatctgtga ctacaacctt cggttcatca aactgcttca ctaaccgctt
    34561 aagaaaagca taggctgctt gtgtgtcccg ttttttacgt aaccaaatat ccaaggttaa
    34621 accatctgca tcgatggctc gatacaaata atgccatttt cctttaattt tgatgtacgt
    34681 ttcatccatt ttccatgaat aaaaggattt tttatttttc tttttccaaa tttgatagag
    34741 tagtttgcca tattcttgca cccaacgata aatcgtcgta tgagaaacgt taatgccacg
    34801 atcatataag atttcttgaa cttcacgata gctaaggtta taacgaagat agtagcccac
    34861 ggctacaata atcacatcct gctgaaattg ctttccttta aaatgattca tcgtcattcc
    34921 tcctgctatc tttttctatt attctacctt atttgatagt agatttaaaa ctttggttct
    34981 gttgcaaagt tttaaataaa gaataaaatc ccttacggta tctatgattt aagctgggat
    35041 tcccaataat accttgattt cagtacagac cgaaaacccg aagagagtgc cttcttttcg
    35101 ggttttctta tataatcctc gaatggcttc catgccttta atcgtggtag aggcagtgcg
    35161 taaacttcga tagaatttat tgcgtctctt tactggacga tggtcttgtt caatcaaatt
    35221 attcaggtat ttaatggtac gatgttctgt cccttgataa aagccgtatt cttttagttt
    35281 cttaaaggca cttgtaatag agggggcttt atctgtgact acaaccttcg gttcatcaaa
    35341 ctgcttcact aaccgcttaa gaaaagcata ggctgcttgt gtgtcccgtt ttttacgtaa
    35401 ccaaatatcc aaggttaaac catctgcatc gatggctcga tacaaataat gccattttcc
    35461 tttaattttg atgtacgttt catccatttt ccatgaataa aaggattttt tatttttctt
    35521 tttccaaatt tgatagagta gtttgccata ttcttgcacc caacgataaa tcgtcgtatg
    35581 agaaacgtta atgccacgat catataagat ttcttgaact tcacgatagc taaggttata
    35641 acgaagatag tagcccacgg ctacaataat cacatcctgc tgaaattgct ttcctttaaa
    35701 atgattcatc gtcattcctc ctgctatctt tttctattat tctaccttat ttgatagtag
    35761 atttaaaact ttgcaacaga acctttttgg caatactggt attttgtttg atcttttggc
    35821 gctttgtatt agcccttgtg agtctactat tcaagatgat tgcagccata tttttcatag
    35881 ggttatttcg atgaaaggag agagtactaa tgccaattgc aataggaaat aaacggttac
    35941 ccgttacgtt ggatgaaaag agacaaaaag aattgcagca actaaagcag aagtacggca
    36001 aaagtgaatc caggattatg tgtattgcgt tagatttatt gattgcccaa gaaaaagcag
    36061 gatttgaggt accagcactc aaaaagtgac gtcacttttt atcctaaaaa ctaaaagtga
    36121 tagcactttt aattataaga agttagaata ttaatcattt gcttaattgt acaatataat
    36181 gtacaattgt tttatagaaa taaataaggg gtgaaaggaa tggaagcagt agcttattca
    36241 aatttccgcc aaaatttacg tagttatatg aaacaagtta atgaggatgc tgaaacactt
    36301 attgtaacaa gtaaagatgt agaagataca gttgttgtat tatcaaaaag agattatgat
    36361 tctatgcaag aaacgttgag aacactttct aataattacg tcatggaaaa aattcgtcga
    36421 ggagatgaac aattctccaa aggtgcattt aaaacacatg acttaatcga ggttgaatct
    36481 gatgattaag gcttggtctg atgatgcttg ggatgattat ctttattggc atgagcaagg
    36541 aaacaaaagc aatataaaaa agattaacaa gttaataaaa gatatcgatc gttccccctt
    36601 tgctggatta ggaaaacctg agccattaaa gcatgattta tctggaaaat ggtccagaag
    36661 aattacagat gaacatagac tgatatatag agttgaaaat gaaacgatat ttatttattc
    36721 tgcaaaagat cactattaac caatcggaag taaggaaagg gtcagaaact taaaagtttt
    36781 tgatccttat tttatttacc ctagtcattt aaaaagctaa tatagcttag tgttgattgt
    36841 tattaatgaa tgtgtttgtt acgcgtatta cggatataag gttagtaaaa tcatttctaa
    36901 agttgaggaa aagtaaatat aaatggctta aatttcaaca atttgaagtt gaatagatat
    36961 gttataatac tattgtagtg tgggatgtta gttactaaag gatgacgctt atatatatga
    37021 ctgaatagaa taagcaatag gtttaataat ctattttaaa ttttttgtac tagttttagt
    37081 taattagcaa aaacaacaaa aataaacttc tcatagaatt tagctaaaaa ttaatgattt
    37141 atttacatat taaatttgga tacagttaag taatttttat atattggagg agaagtaatg
    37201 gaatataaat ttaacttgaa tttgaaagaa gtactcccca ctcagggaac aataaacata
    37261 aatggtcaag ataatgatga cgatatagta ataaaaaaaa tagaatttat tgattctgat
    37321 ataaatgttt ttttttattc taaagaaaaa ttagctgatt ttagcaatat tgctgaaatg
    37381 attgaacgtt taaaagattt tatgatcagt gtttgggatg tagcgatgct tgctgacgaa
    37441 tcaaattata cttcgagcat atacagatta gaagatagta attggataga aatttcatta
    37501 gagttaaaga cacttcctaa ttccgttaac tatataatta gagatataac ttctgaagct
    37561 caacaattag ttaattacat gcatggacac gaaagtatcc ccttttctct tatactcctt
    37621 aaaagaagta aaaatatatc aaatactaga gataggttta tttcgataat tacagcctgt
    37681 gaaatagggg taaaggaatt ttatcaacaa gagaaacctg atttaactct aatatttgag
    37741 aatttacaat ctccccctgt agacaaatta ttagggagca tgtttaaagg gtactttaat
    37801 attgagtttc cgaaagaaat aagaaaggaa attaaaaatt tcatagaaaa acgtaataaa
    37861 ttggttcatt ctcctcaagg aagtaaacca actatagaag aatgttttga atgttatatg
    37921 gcagtgctaa aaacatttaa ttttttttat aaaattaatg atagctttat gtatagagat
    37981 ttttatgaag aatctataga attgactcca acggaaccaa ataaatctca aatcactttg
    38041 tcaaaggagc tagagagaaa agtagagtct caagaactag ctataggaat tagtataacc
    38101 aatgtgtcga catacaaaga attatacgaa gctaaatcac aagataataa ggattttgta
    38161 gaaaatatag ataaggaacc aacaaataca gtaggggatt aacgtaaata agtgaagatt
    38221 atattaacag actctttatt tagttaagta aaaaatggtt tgttggaatt ttatgcttta
    38281 tctgttctga gtaagactta attttataga tagtaattat atgtaggaaa ttaaagatga
    38341 gaagataata aaagcagcat gatcaactat ttgtcattga ccatgctgtc tttttttatt
    38401 ctatacacgg tttgtctcgt aacattgtag tctttagcaa tcttagcaat cgcaacacca
    38461 tttttaagat cttcaacgat gcttttgtaa acaaggcgac gttggggatc ttttgcgtct
    38521 gcactgtata atttgggccg ccctttgtag acgccgtttg cttttgcgat cttaattcct
    38581 tgtgcctggc gacgtttcga ttcagtccgt tcttgttcag cgatcatggc caaaatttgg
    38641 atgatcagat ccttaatgaa tttatccagg agaggattgc caattgcttc agccatgatc
    38701 ggtaaactag taatgatcag cttcacattt ttcttcttca agtaattgac tgaagcgatg
    38761 atctcgtcat aatttcttcc aagtcgatca atagcttcca caataaaaat atcttgatct
    38821 cggacgtaat ctaatgcttc ttggaaaaca ggtcgatgag taatcgttgc gccagattgt
    38881 ttctcgatga aaattctctc tgcaccgaat tttttcattt cttcaatctg gcgttgttca
    38941 ttttgatcga tcgatgagac acgtatgtat gcaactctca aaacttttac ctactttctg
    39001 caactattta aaatacaccc taatcataca cgaggaagcc atatttttca atgttatacc
    39061 agtgtctatt tagggtaaac cttatataga caaaaactaa tgatggagga aatagtatga
    39121 gaattttttg taagtgtcta ctgataactt attctcaaat gttgtaagga ttttattcat
    39181 ttgttaatat taaagaacgg aactccaaaa aagtccgtac tctaatttgc agtctctcac
    39241 tcttttagag tgagagtttt tattagattt tcaaattaat tagtaaagtg atagaataaa
    39301 ttgatcatac aaatcaaaag aagaagcagg gtgatagcat acctatgctt ctttttttat
    39361 gtatttagct atttcttctt tacaatatcg aacatatgtt tgtataatgt gaaagaatgg
    39421 agtgttattt atgatggatt attcaaaaga gccagtaaat gattactttt taatcgatat
    39481 gaaaagcttt tacgcaagtg tcgaatgtat agaaagaaat ttagatccat taacaacaga
    39541 acttgttgtt atgagtcgag ctgataatac tggttcagga ttgatattag cttcttctcc
    39601 tgaagcaaaa aagcggtatg gtattacaaa tgtgagtaga ccacgtgact taccacaacc
    39661 atttcctaaa acactacacg ttgttccacc acgtatgaac ctatatatca agcgaaatat
    39721 gcaggtaaat aatattttca gaagatatgt ggctgatgaa gatctactga tttactcgat
    39781 cgatgaatca atcttaaaag tgacccgatc actgaatctt tttacgactg aaggaacacg
    39841 aagtcaacgg agaaagaagc tggctcaaat gatccaggag aatattaaag aagagctagg
    39901 attgattgct acagtaggtg tcggagataa tccccttttg gctaaactag ccttagacaa
    39961 cgaagcaaag cataatgaag gatttgttgc ggaatggacg tacgaaaacg ttcctgaaaa
    40021 agtatggaat attcctgaaa tgacggactt ttggggaatt ggctctcgaa tgaaaaaaag
    40081 actcaatcag atggggatta tgagcattag agatcttgct aactggaatc cttatacgat
    40141 taagaataga ctaggtgtga ttggcttaca gctgtacttc catgctaatg ggatcgatcg
    40201 aacagatata gcaatcccac cagaaccgac aaaggaaaaa tcatatggaa attcacaagt
    40261 gttaccacga gattatacta gaagaaatga aatcgagctg gtggtaaaag aaatggcgga
    40321 acaagtagcg atacgcatta ggcagcataa ctgtaaaaca ggttgtgtcc atttacacat
    40381 tggcacgtcg atcttagaaa cgagaccagg gttttcacac cagatgaaga tccctatcac
    40441 agataataca aaggaattgc agaattattg tcttttcttg tttgataagt attatgaagg
    40501 acaagaagta aggcatgttg gaataaccta tagcaagctt gtgtacaccg attcgcttca
    40561 gctggattta tttagtgatc cacaaaagca aattgacgaa gaaaatttag ataaaattat
    40621 tgacaagatt cggcaaaaat atggttttac gtcgattgta catgcttctt caatgttaga
    40681 aggcgctaga agcattacta gaagcacact tgttggtggt catgcgggcg gaaatggggg
    40741 aattaaaaat gattgattac aatgatcgtg gacgtttaaa gtgggcaggg ttttatttat
    40801 ctgatcatac tgaagaaatt gatgccgaca atgaacaacg aaccagtcaa aatttagcaa
    40861 aagaacaaat gacgactgaa gagattgcgg aagtattgaa cgctgcagtc ataaaaaata
    40921 gatcagtatc tattcaaaaa gaagaacgaa acgctgaagg atactatcca gaagatatca
    40981 ttggcaagat cttaggtagt gatgagctgg ggatctacgt tggaaaagac aaaattcact
    41041 acgacgaaat acgtcatatc gaattttacc aggataataa atggagtcga ttagaatgaa
    41101 cattatccag caatatgagc taaagtatat aacctttgat cagctatcag aagagatttg
    41161 gggttatggc caacgtttga taaatgaggt tggtgttgag cgcttctctt tctatgtaga
    41221 agctgcagca ggttatcata attttaggtt ttatatcttc ccgttatata tataaggtat
    41281 tttacggatt ctatagagtt atctctatga atcctttttt gtttttacaa ataggagtag
    41341 atactagaat aatgcgtgtg ttaaactatt attgcaaacg caataataaa agaaagtagg
    41401 cttacgcacc atgtctatca atacatttgt ttactcgcac ccgatcaatg tttacattat
    41461 caagaattta ggaatcactg tagaacaatt ttgtgagtta tatgcctacc cacaaggaac
    41521 ggttgcaagc tggataaccc gacaacgtag aataaaatca ttacctgctt cattcgttta
    41581 tgatttaagc ctggcctcta gtttaaacat gtctgatgtt tatgaaaagc tcctgtcttt
    41641 agaaaaagaa tatgattcct tcaagattaa acatgataaa aaaataaaaa aacatatata
    41701 atatcaatca caattgtata atattacgat atcttaatat catgatatcg taatattgtt
    41761 tttttctaag aaaatgcact ataagaaggg aattattagt aacaatatag acagtttagt
    41821 aatgtttaaa ttattctagt tgctgctcgc aaaacatatt tcttatcatt aataaaaaat
    41881 tttaaagtaa taaaaagtga ttattttaat ttcgaataac atatgaataa tctttatatc
    41941 cgaaccgata tatatcttta aaacaaaata atcacacaat attacaatat aatgcatata
    42001 cgatattgca atatcacaat attatgatat aattatatta taatataaga tgaatggggg
    42061 atattttaat ggcaagaata ttgtcagtag ccaatcaaaa aggtggagtt tctaaaacta
    42121 cgactagcgt taatttagca gcatgtttga aatttgttta cggtaaaaat gtacttttag
    42181 tggacattga tcctcaggga aatgctacag ataatgtagg tttcgatata gatggaacaa
    42241 accaacctac aatttatgaa gtattaaaag gggaggctga cattacagat gctattctgg
    42301 actataaagg aattgatgtt ttgccagccg acatagccct ttcttctgca gagagggaat
    42361 ttactcaagt aggaagtgaa cacaggctta aaagagtact tcaaccaatc aaggacaact
    42421 atgattatat tataattgat tgtccaccaa gtttaggaat gcttacagtc aacgcattta
    42481 ctgtttctga tgaaattatc attccagttg aagctgcgta tttctcatta aaaggactaa
    42541 taaagttaag tgaaactatt gaaacggtaa aagaatatac gaacgacaag cttgaagtac
    42601 gaggagttct atttactaag tataataagc gttataacat ttctaaagaa atgacgtctg
    42661 cagcaaccga aatttctaga gtcattggtg caaaaatttt caaaacttat attcgtagga
    42721 caataaccgt tgacgaagcg caagctgctg gatcagatct aatcaatttt aataaaccct
    42781 caacagctga agatgactat aaagcattta cagaagaata tttaaaagaa gttggtgatt
    42841 ttgatggcag aagataatcg cagtcaagct gcagtaagta gattactagg aaataaaaat
    42901 aaaaagaatt ttaaatcaaa agaagtagaa gaaatcgaat taaccaagaa aaatataagt
    42961 aaagtcataa aagatcaagg aagtagtgta agaacagcag atagcattcg tataaatcca
    43021 attctaatgt cagcactcaa atattggacg actattgctg aatcagacaa aagtaaacca
    43081 gacgttatag aagatgcgct attaaagtcc atacctgaag aatacttgat tgaaggatat
    43141 aaactagcaa agaaacaaaa taaaatttaa tttacattca atatcacgat atcataatat
    43201 cgtgatattt tttttataaa aatcagtagt atcaaagctg ataagtcgct tatcttcata
    43261 ttgtaatatt acgatatcgt gatataatat tattgtaata tcgtgatata gttactatga
    43321 gcttaaacct tgaaatagag cggtttgctt taatttattt tttaaggtaa actaaaaaaa
    43381 gataaaaaaa gactactgct ttaacaaagt ttggcgactt atcagcagta gaaaaatata
    43441 tagtggatag atatatttgt ttaattcatt gtaacatagt tttgaacaaa acgctatcct
    43501 acagaaagag gattggct
//
