LOCUS       NZ_CP064023            33858 bp    DNA     circular CON 11-JUN-2024
DEFINITION  Escherichia coli strain EC35CM1 plasmid p35CM1-IncX4-mcr-1, complete
            sequence.
ACCESSION   NZ_CP064023
VERSION     NZ_CP064023.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN16604541
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 33858)
  AUTHORS   Leangapichart,T. and Sunde,M.
  TITLE     Co-occurrence of mcr-1, mcr-3, and blaCTX-M genes in Escherichia
            coli from pigs and humans in Thailand
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 33858)
  AUTHORS   Leangapichart,T. and Sunde,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-OCT-2020) Animal Health Welfare and Food Safety,
            Norwegian Veterinary Institute, Pb. 750 Sentrum, Oslo 0106, Norway
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method              :: Unicycler v. 0.4.8
            Genome Representation        :: Full
            Expected Final Version       :: Yes
            Genome Coverage              :: 200x
            Sequencing Technology :: Oxford Nanopore MinION; Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI RefSeq
            Annotation Name              :: GCF_030061415.1-RS_2024_06_11
            Annotation Date              :: 06/11/2024 05:14:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision :: 6.7
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 43
            CDSs (total)                 :: 43
            Genes (coding)               :: 43
            CDSs (with protein)          :: 43
            Genes (RNA)                  :: 0
            tRNAs                        :: 0
            ncRNAs                       :: 0
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP064023.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..33858
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="EC35CM1"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="p35CM1-IncX4-mcr-1"
                     /geo_loc_name="Thailand"
                     /lat_lon="16.6111414 N 102.0574847 E"
                     /collection_date="2018-12"
                     /collected_by="Thongpan Leangapichart"
     gene            1014..1880
                     /locus_tag="ISD17_RS00005"
                     /old_locus_tag="ISD17_00005"
     CDS             1014..1880
                     /locus_tag="ISD17_RS00005"
                     /old_locus_tag="ISD17_00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001473366.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_001353743.1"
                     /translation="MTTNKTSLSRLTKVRHRNELNSTLSTLPMAAKKVLFLAMCQINSK
                     NEFDDDHIFYVTVADYIKWVQVKPDAAYLALRDGSNILDTTLLKLKHDEILELSSDLGF
                     KFTKSNVPDSMNLSLTVFSTYYRNEGRVGIKFTKEAKRFLCKLIGEEKRYTTQVLLSVV
                     RLTSVNAASLYQLIRKIYSNNSRANSFEMTIDELKDELNLYTIGAGGVKDYKYPDYPAF
                     KRDVLNKSVKEIMKHTEVKNLSFVVSEKIGRKVYKLKFSYTIGYEGDTREDSEFTNMFD
                     KMYPPEN"
                     /name="replication initiation protein"
     gene            1893..2297
                     /locus_tag="ISD17_RS00010"
                     /old_locus_tag="ISD17_00010"
     CDS             1893..2297
                     /locus_tag="ISD17_RS00010"
                     /old_locus_tag="ISD17_00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012421203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_012421203.1"
                     /translation="MKDNIVDFQRIRDSMNDHSTDVANDAVYSDKKKISRFFYLLTPVR
                     YLLAASLYLVVVIPLGILAGFRFLLQFLGGIAVMGLTIAWYMGADVSSYVVLAAWIALT
                     VCGCAEQIFEWWIESRFAFRLFGIGRTPEE"
                     /name="hypothetical protein"
     gene            2432..2959
                     /locus_tag="ISD17_RS00015"
                     /old_locus_tag="ISD17_00015"
     CDS             2432..2959
                     /locus_tag="ISD17_RS00015"
                     /old_locus_tag="ISD17_00015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001473365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2726 domain-containing protein"
                     /protein_id="WP_000577043.1"
                     /translation="MIFNRNKKRDEQHNSAVVLPSAENVFSDFIKNNPALTTNAFTAIG
                     EVDCFTKVPLLSNNESEFLGILSRNIIPDYSVFPKIRLIEFVRPHGSEEAVKDLIREVQ
                     NITCDFVLKSYDETVLAVIQFGETATVRQQKKKLIIQRVCAMTGISFFEFKNTVDMMGS
                     EDFCQFLRDDEE"
                     /name="DUF2726 domain-containing protein"
     gene            complement(3111..3368)
                     /locus_tag="ISD17_RS00020"
                     /old_locus_tag="ISD17_00020"
     CDS             complement(3111..3368)
                     /locus_tag="ISD17_RS00020"
                     /old_locus_tag="ISD17_00020"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2806 domain-containing protein"
                     /protein_id="WP_223369243.1"
                     /translation="MRVFIICIFKSKNGRIGYYGTVFSVEFQSDDSSTWKLPIGTALLT
                     PIGQELMKICGSTPDIAYLNKFLNKINVEGSQVKLSIINM"
                     /name="DUF2806 domain-containing protein"
     gene            3532..5157
                     /locus_tag="ISD17_RS00025"
                     /old_locus_tag="ISD17_00025"
     CDS             3532..5157
                     /locus_tag="ISD17_RS00025"
                     /old_locus_tag="ISD17_00025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_049589868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine--lipid A transferase MCR-1.1"
                     /protein_id="WP_049589868.1"
                     /translation="MMQHTSVWYRRSVSPFVLVASVAVFLTATANLTFFDKISQTYPIA
                     DNLGFVLTIAVVLFGAMLLITTLLSSYRYVLKPVLILLLIMGAVTSYFTDTYGTVYDTT
                     MLQNALQTDQAETKDLLNAAFIMRIIGLGVLPSLLVAFVKVDYPTWGKGLMRRLGLIVA
                     SLALILLPVVAFSSHYASFFRVHKPLRSYVNPIMPIYSVGKLASIEYKKASAPKDTIYH
                     AKDAVQATKPDMRKPRLVVFVVGETARADHVSFNGYERDTFPQLAKIDGVTNFSNVTSC
                     GTSTAYSVPCMFSYLGADEYDVDTAKYQENVLDTLDRLGVSILWRDNNSDSKGVMDKLP
                     KAQFADYKSATNNAICNTNPYNECRDVGMLVGLDDFVAANNGKDMLIMLHQMGNHGPAY
                     FKRYDEKFAKFTPVCEGNELAKCEHQSLINAYDNALLATDDFIAQSIQWLQTHSNAYDV
                     SMLYVSDHGESLGENGVYLHGMPNAFAPKEQRSVPAFFWTDKQTGITPMATDTVLTHDA
                     ITPTLLKLFDVTADKVKDRTAFIR"
                     /name="phosphoethanolamine--lipid A transferase MCR-1.1"
     gene            5205..5957
                     /locus_tag="ISD17_RS00030"
                     /old_locus_tag="ISD17_00030"
     CDS             5205..5957
                     /locus_tag="ISD17_RS00030"
                     /old_locus_tag="ISD17_00030"
                     /inference="COORDINATES: protein motif:HMM:NF028536.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAP2 family protein"
                     /protein_id="WP_077250698.1"
                     /translation="MGGGVGFVMPYLSNKRLLAEMSIALVMAIVATLTLEHSQIDLMVA
                     DWFYLGMGHWMVAKQAFLPDLLLYSGLKKLLMAMLIYLLVATICRAYHEKKGNAITAKW
                     LVPVTKFRVRELAYLVLTLILVPTVVASLKAYTHVVCPVHLTIFDGTLPYLPMLDSMRN
                     TIPDKCFPAAHASSGFALFAFAFAPSLRRRRGAIIIVVMALGWAMGCYKMIIGDHFLSH
                     TVVSMMLAWAMSAGLAWVFFKKGEQSRG"
                     /name="PAP2 family protein"
     gene            complement(5946..6569)
                     /locus_tag="ISD17_RS00035"
                     /old_locus_tag="ISD17_00035"
     CDS             complement(5946..6569)
                     /locus_tag="ISD17_RS00035"
                     /old_locus_tag="ISD17_00035"
                     /inference="COORDINATES: protein motif:HMM:NF022440.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2806 domain-containing protein"
                     /protein_id="WP_223369242.1"
                     /translation="MSLIDLSLSGLSEPGTKLIEKISDAIGVLYEPTRIRKKAKAEAEA
                     KRTELISRLELEGIEKRAVERFLKRETKRQENIENITMQAAQSLSESDNVSDIDEDWIE
                     AFFRECEDISDEQMQMLWGRILSEEAKSKGSFSRRTLKLLSTISKEEANLITYFGKFVW
                     QANKLTPILFTDENGDTEGITFDKLSVLDSLGVIQQGIGYSLTS"
                     /name="DUF2806 domain-containing protein"
     gene            complement(6730..6999)
                     /locus_tag="ISD17_RS00040"
                     /old_locus_tag="ISD17_00040"
     CDS             complement(6730..6999)
                     /locus_tag="ISD17_RS00040"
                     /old_locus_tag="ISD17_00040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001086090.1"
                     /translation="MAKLELPELEQNQEVNATKFVQDAGKRPTENKTKLASFRIPNELL
                     EFIDNESKRLHRPKTKIIKAALLAYQDLDENELINLWFRADRND"
                     /name="hypothetical protein"
     gene            complement(7074..7721)
                     /locus_tag="ISD17_RS00045"
                     /old_locus_tag="ISD17_00045"
     CDS             complement(7074..7721)
                     /locus_tag="ISD17_RS00045"
                     /old_locus_tag="ISD17_00045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001694199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division plane positioning ATPase MipZ"
                     /protein_id="WP_000587671.1"
                     /translation="MIIVIGGDKGGTGKSHLATNLTVCLSQQGKRTGLVETDLNGSTKK
                     WNKRREQAGLPPVALNEAYGDISAKITKMADVAEILIIDTAGYDSTEFRTALKVADIVI
                     VPIDPLAQVEADSLQTVTKIVRDAQKINPRLAAHVLLYKCQPNTFSEQQELRDSLNSHD
                     YWLKPMKSTVSFLRAFVRAMNQGMGVHELKSNVSGASQAKAQIELLLKELEL"
                     /name="division plane positioning ATPase MipZ"
     gene            complement(8384..8479)
                     /gene="dqlB"
                     /locus_tag="ISD17_RS00050"
     CDS             complement(8384..8479)
                     /gene="dqlB"
                     /locus_tag="ISD17_RS00050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinQ-like type I toxin DqlB"
                     /protein_id="WP_021534057.1"
                     /translation="MINMLIIVLRAVVAVANALIAVLELIRQFID"
                     /name="dqlB"
     gene            complement(9225..9689)
                     /locus_tag="ISD17_RS00055"
                     /old_locus_tag="ISD17_00050"
     CDS             complement(9225..9689)
                     /locus_tag="ISD17_RS00055"
                     /old_locus_tag="ISD17_00050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293133.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0030527 - structural constituent of chromatin [Evidence
                     IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS family nucleoid-associated regulatory
                     protein"
                     /protein_id="WP_001293134.1"
                     /translation="MSELTKEDEYGIISRTMMNIRSLRVFAREIDFEQLLEMQEKLNVV
                     IEERREDAEREAAERQELEAKRQQAIEYIISLGLDPESLLAPVTADTVKTRRKAKGGVR
                     KAKYRFKDENGEIREWSGNGKRPLALQKLLDEGHFMEDFLIEKTKPEQAE"
                     /name="H-NS family nucleoid-associated regulatory protein"
     gene            complement(9707..9913)
                     /gene="hha"
                     /locus_tag="ISD17_RS00060"
                     /old_locus_tag="ISD17_00055"
     CDS             complement(9707..9913)
                     /gene="hha"
                     /locus_tag="ISD17_RS00060"
                     /old_locus_tag="ISD17_00055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="WP_000850859.1"
                     /translation="MKTKQEWLFQLRKCTSRDTLEKVIEINRYKLPLSESEAFYSAADH
                     RRAELVMNKLYDKVPSGVWKYVH"
                     /name="hha"
     gene            complement(9910..12063)
                     /locus_tag="ISD17_RS00065"
                     /old_locus_tag="ISD17_00060"
     CDS             complement(9910..12063)
                     /locus_tag="ISD17_RS00065"
                     /old_locus_tag="ISD17_00060"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247728.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="WP_001235745.1"
                     /translation="MRLFIAEKPAVANDIVKALGGNFTRHDGWFESDNAIVTNCFGHII
                     ESQPPENYNPEYKAWKVETLPLRLYPVKYQPVESAAKQVKTILELIRRGDVTEIVHAGD
                     PDDEGQLLVDEVLEYAGNTKPVKRVLINDNTLPAVKKALANLKDNRDFKGLYLKALARS
                     VADAVYGFSMTRAYTIPAKARGYQGVLSVGRVQTPVLGLIVNRTRANQNHKSSFYYTMT
                     GVFQRGADVIRANWKPGEFAPLTDRKLLDKAWADGTAASLAGKPATVEAAATDDKKTAA
                     PLPFNLVRLQQYMNKKFKMTAQKTLDITQQLREKYKAITYNRSDCSYLSDEQFSEAPQV
                     IDALKSVFPQSLDIDSARKSKAFNSAKVTAHTAIIPTASVPDVNALSTDERNVYLAIAQ
                     HYLVQFMPEKAYQEVSVAIQCGDESFYARARKTTDSGFEAFLGAETTDEGESEDNDDSA
                     FELLCKIRTGETLTTKEVIVNEKKTTPPPLFTEASLLAALVRVADFVTDPTIKKLLKDK
                     DKDKKDEHGGIGTPATRAAILETLKKRNYITLEKGKLIPTDTGYALIDALPGIAVNPDM
                     TALWSEKQAAIENGDLTVEQFINDLYGELTGMISDVDLGEMKIEPAAPAGQFQRLDSPC
                     PSCGKHIVIRPKGYFCTGCEFKIWSEFSGKKITQAQAEKLVKSGKTDLIKGFKKKSGGT
                     YDTVLVLEDKKTGKLGFPARAKK"
                     /name="type IA DNA topoisomerase"
     gene            complement(12068..12643)
                     /locus_tag="ISD17_RS00070"
                     /old_locus_tag="ISD17_00065"
     CDS             complement(12068..12643)
                     /locus_tag="ISD17_RS00070"
                     /old_locus_tag="ISD17_00065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001199074.1"
                     /translation="MQYALVDALERKFLLDALEFGVLKDWKENPVKELPDIDESVHPFH
                     VCYGGYLLNPGVSDSDISRKIKDQTGFWLAAIDDTRMDCHSIAYYDIHTLPLILCGHQK
                     IVPFAALIKADECIISKIASYSGFAVTAFLRIKDQDIATNILNREGIFAFNGCERRFRQ
                     PVSEDNWQQAVSEERAIRCANRLIQCKG"
                     /name="hypothetical protein"
     gene            complement(12749..13153)
                     /locus_tag="ISD17_RS00075"
                     /old_locus_tag="ISD17_00070"
     CDS             complement(12749..13153)
                     /locus_tag="ISD17_RS00075"
                     /old_locus_tag="ISD17_00070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001576899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001218543.1"
                     /translation="MALSPKEKKELQQRFEKQLLPDLDMSFELNGEVYKFNFDKNESGD
                     YIDSFTQAVWGGYQDAEEWEKYGKHQETELPECPEPVEGWCDCDKCKSMIFHKEKNIYV
                     CLSCHKQTEPFLPIDWNSNDYDWLPYEDEY"
                     /name="hypothetical protein"
     gene            complement(13169..13663)
                     /locus_tag="ISD17_RS00080"
                     /old_locus_tag="ISD17_00075"
     CDS             complement(13169..13663)
                     /locus_tag="ISD17_RS00080"
                     /old_locus_tag="ISD17_00075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001215543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="WP_001215680.1"
                     /translation="MRHFLKALSFVVSLLPATLCAAEIQGKVIRVLDGDTIEIKTLPAK
                     IVVYEVPIRVRLINIDAPEKKQPFGRWSTSQLKTLVAGKQVTVSYSHKDRYGRIIGHVF
                     TTNGTDASRFMVQSGAAWVYERYNVDESLPALQREAQEQKRGLWADANPVPPWEWRYKH
                     N"
                     /name="thermonuclease family protein"
     gene            complement(13660..13968)
                     /locus_tag="ISD17_RS00085"
                     /old_locus_tag="ISD17_00080"
     CDS             complement(13660..13968)
                     /locus_tag="ISD17_RS00085"
                     /old_locus_tag="ISD17_00080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000647576.1"
                     /translation="MKARSVRVAGIEIIDSVKTVAFVFTETLLFMVWFSAIVYGLYRVV
                     IVLWDDPLKPQSLMEFLNFIVELYSYVLPSLAVIAVALIAVLSICKILSAIWEGRKQ"
                     /name="hypothetical protein"
     gene            complement(14071..14325)
                     /locus_tag="ISD17_RS00090"
                     /old_locus_tag="ISD17_00085"
     CDS             complement(14071..14325)
                     /locus_tag="ISD17_RS00090"
                     /old_locus_tag="ISD17_00085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000415096.1"
                     /translation="MEKQTTDLLNVIKTGHSGSIAGNPAHALDDKTMNAIIHNYVATIV
                     LGKAGNCKETPLTKYCSRTMPERISVEEINEFKIYPELF"
                     /name="hypothetical protein"
     gene            complement(14331..14636)
                     /locus_tag="ISD17_RS00095"
                     /old_locus_tag="ISD17_00090"
     CDS             complement(14331..14636)
                     /locus_tag="ISD17_RS00095"
                     /old_locus_tag="ISD17_00090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000147044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_000147044.1"
                     /translation="MTGKNRVVLPALLALGLISTNANASDPCASVLCLYGKAVGQGGGS
                     ECRSAEKDFFNILKKKKGSIRWSKTFDARKAFLNQCSTADPAAISKIMSKFGKVKG"
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            complement(14620..15042)
                     /locus_tag="ISD17_RS00100"
                     /old_locus_tag="ISD17_00095"
     CDS             complement(14620..15042)
                     /locus_tag="ISD17_RS00100"
                     /old_locus_tag="ISD17_00095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001353737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="WP_015059903.1"
                     /translation="MMKKLVFLLISILAGCSSPPEPTPVQFEKANEVINPSLPYVPDFH
                     GVIKSDVSGKGWVYEITSLSGVQARTPTFYYALAHADRIVVTTHDAGLWFRIRDLLKME
                     GATAVVEWRNEKSFLPEQVKIVFIKAQNEVKNDWKK"
                     /name="cag pathogenicity island Cag12 family protein"
     gene            complement(15051..16913)
                     /gene="taxB"
                     /locus_tag="ISD17_RS00105"
                     /old_locus_tag="ISD17_00100"
     CDS             complement(15051..16913)
                     /gene="taxB"
                     /locus_tag="ISD17_RS00105"
                     /old_locus_tag="ISD17_00100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome-coupling protein TaxB"
                     /protein_id="WP_170324155.1"
                     /translation="MKTFNKSQSVFIFAVMLVAAWFAGSFIFFVLYFSQIKNLKPLKAV
                     FRSIDAYRMDIFTDSLTLSVVTTDIRVLAFVALGAGFVVSLIIPVAALIKLNEKKENIF
                     GDARFATINDIRESNSFTLDGDEKDGIIVGIKDKKIIRYVGAAFSAMGAGTRAGKGAGI
                     VITNLMKYWWSVIILDPKRECFNITSLIRKVILGHEVYKFDPFSSVTHRFNPLYYVSMG
                     TSEGFNQLENLSLIIYPYKTDGADAGSYLNKTAGGVFKSYAVALWFMIKNDKAGLKTLD
                     IEPVFSMSKINQLFERAEPEHLLSFMNDIRSELRGKDKTLADIGVAGLKAFIEMEDKTK
                     AQLKSNFLNGLSPFANPNVANATDGNDFDLRQVRKKRMTIYFCISGDNARLAEKITNIF
                     FQLAIQVNLEKMPTDDPEIKHDCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQV
                     GSQLEEIYSYAGSKTLLASAPCKIVYSASDVKDARELSEAMGTRTVTIGSKSKSRSRGG
                     TSRSESESLIERPLVTTNELLTLKFSEEILAMKGENPIRCEKAFYYLNEYFFGDFVKVA
                     PELANIFPRKKGKLVMPPQKVFENEIVAKGYLVVKDVPDLDKAA"
                     /name="taxB"
     gene            complement(16900..17928)
                     /gene="virB11"
                     /locus_tag="ISD17_RS00110"
                     /old_locus_tag="ISD17_00105"
     CDS             complement(16900..17928)
                     /gene="virB11"
                     /locus_tag="ISD17_RS00110"
                     /old_locus_tag="ISD17_00105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401678.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_077250700.1"
                     /translation="MSGVIPVSISNKSLDFYKNQVFQSFLDIEGLTEIAVNRPGEIWTE
                     INGDWTFHNNNSVTFDFCKRFSHTLASFRGDEIGETKPLLSATLESGERVQVVFPPACE
                     RNTISITIRKPSTRQITHKEYVANGFYDYVQSGKKHRTYDDELLDLFRARNIAAFMELA
                     VAAGKTIVFAGATGSGKTTYMKSLIDFIPLNTRLITIEDAEEIKFFIHKNYVHLFYPSE
                     SGSDSGSIITAAKLIKSCLRMKPDRILLAEIKGGDAWDFVKVAGSGHSGSMTSIHAASA
                     KDAIIQMVTKCYQNRECQNLPFDVLRKIIMDSIDIVVHVGRDGVVRHMSDIYYKGAECE
                     NF"
                     /name="virB11"
     gene            complement(17930..19048)
                     /gene="virB10"
                     /locus_tag="ISD17_RS00115"
                     /old_locus_tag="ISD17_00110"
     CDS             complement(17930..19048)
                     /gene="virB10"
                     /locus_tag="ISD17_RS00115"
                     /old_locus_tag="ISD17_00110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB10/TraB/TrbI family type IV secretion system
                     protein"
                     /protein_id="WP_000131271.1"
                     /translation="MTDMKKTDDLVDDANQSKLESKPVHDIGDIRNKNNRMRSGFLFGL
                     MAVLVIGIFALKTYKNYFADDQQKASESTGDTSISQVSKIRTGLGQNFDPVENKAIINP
                     GATGSGNTVSDGHKEVPQEGFRKYLSIPVAGQGGSQTGASGSSRTSQTSEPQEERKESK
                     ENVPGKSGMKVTAINLDPDLYIEENRLIPCALTTRFVSDVAGRISCVFTEDVWSANHHT
                     KLLEQGTKAFGRYQTGTLNHGQGRMFVMWEQLRTPDNKRIDMVNTAAAGPLGEAGIDGW
                     IDSHFWERFGGSLMLSMVQDVAAAAADNAPGKDRNVDYTENSRQAMAEMAKVALENSIN
                     IPPTMYKNQGDIITIMVGEDIDFSDIYELKVK"
                     /name="virB10"
     gene            complement(19041..19949)
                     /gene="virB9"
                     /locus_tag="ISD17_RS00120"
                     /old_locus_tag="ISD17_00115"
     CDS             complement(19041..19949)
                     /gene="virB9"
                     /locus_tag="ISD17_RS00120"
                     /old_locus_tag="ISD17_00115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001299943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein VirB9"
                     /protein_id="WP_001329500.1"
                     /translation="MMKKLFIATCLLLPGLVYSAATPLPSGFDARMQTVSYNGANTTVI
                     RSKTGFLTSVVFDEGEAVISAKAGFPAGWEITTDDNVVYINPRPVVQEQEGDEGEKLKK
                     VFQPTEKEWDTNLFVRTTKRIYSLDLILLSEEKQAQPAYVVQFRYPSEIAKKNAEEVRL
                     AKEKQEKLRQKKLISESFEKADAPKNWNYFMRVNEKYDSRRIAPDFAYDNGIFTFLGFN
                     SGKVFPAPFAVRDGQEQTLAFNVETKGKYKIMVIHNVNDKFVLRYGNSVVGVVNKSFGK
                     VLTDQRNTSSPAVERVEVNND"
                     /name="virB9"
     gene            complement(19946..20632)
                     /locus_tag="ISD17_RS00125"
                     /old_locus_tag="ISD17_00120"
     CDS             complement(19946..20632)
                     /locus_tag="ISD17_RS00125"
                     /old_locus_tag="ISD17_00120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_001290765.1"
                     /translation="MSEKIEKKIETAKSFERQLYAENERSKKNAWRVAVAASLLSLCLG
                     AAICVLVPLKEKELAIVAVGEKTGRTELITQVKQEKILQSEALGRYFVNTYITLREGYN
                     YPSLQYDYETVQLYSSNTVKDDYLRLYNSDMAPDKIYHNNGSYVAVEVISNIISDATAP
                     DKLASVRFKKTTRNFTTGQVSVSYWTARVTYRFEPEKSVKSSSRELNPLGFTVTSYQTD
                     REVRGE"
                     /name="type IV secretion system protein"
     gene            complement(20971..21120)
                     /locus_tag="ISD17_RS00130"
                     /old_locus_tag="ISD17_00125"
     CDS             complement(20971..21120)
                     /locus_tag="ISD17_RS00130"
                     /old_locus_tag="ISD17_00125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012421205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_227648764.1"
                     /translation="MSLNWILVFVDKHITSGWSRKRKLITQLVILITGITLFKVLGGIS
                     QSWL"
                     /name="hypothetical protein"
     gene            complement(21147..22241)
                     /locus_tag="ISD17_RS00135"
                     /old_locus_tag="ISD17_00130"
     CDS             complement(21147..22241)
                     /locus_tag="ISD17_RS00135"
                     /old_locus_tag="ISD17_00130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001677777.1"
                     /GO_process="GO:0030255 - protein secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000046889.1"
                     /translation="MAQGFFVKYNSTVMDSVDKISSSYQTQFANDIMSLATVSVTLYVL
                     WKGYQILASKTQTPLQDLVWDLSKFAIIIMFITNADGYLTAATDALQGMKDGFSGGVSV
                     WQTLDNLWKSTQNLGAEIYSLDKSTYVKDQGVVGQFLIWTGSLILMAVSVVVFLTADVT
                     MKLLIITAPIFIFCLMFGFIRSMFNNWLQSLFSSILTVLFASLVIRIAMDFQGMILSHA
                     IRAAQTGNVNLVSTGAMGFMAGFLGALLVLIAKGFAVQLAGAGVEGAVQGAAMMGLGAA
                     GMATGKSLMLGGRAGLGFGLGMAGRTGMNSLSGKAGNLMGRGARTAAEWAGEKGYQALA
                     PTGALGMKARRLASLEKARARNAA"
                     /name="type IV secretion system protein"
     gene            complement(22253..22969)
                     /locus_tag="ISD17_RS00140"
                     /old_locus_tag="ISD17_00135"
     CDS             complement(22253..22969)
                     /locus_tag="ISD17_RS00140"
                     /old_locus_tag="ISD17_00135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000832283.1"
                     /translation="MKRVKTLMLISLLTASFYSSAGIPVAIDASPEWAVEAARWTERLK
                     QWSETAQHYQSQIQAYKDQLATATGIRNIAAFTNELSNLQSELTNIYKQGNSYISDFTS
                     NPEGALSSQAKNLFSKYGAFDMCNTGYERNDNLCKARIVSTAASIEQGNEINKQLSSAM
                     SQIQSLSSRIEASKDIKESQDLANALQAQSLKMQAIKMQYDVWNNKNKADHEMLVTQEQ
                     EAFIKQQKEAEPLTFD"
                     /name="type IV secretion system protein"
     gene            complement(22981..25728)
                     /locus_tag="ISD17_RS00145"
                     /old_locus_tag="ISD17_00140"
     CDS             complement(22981..25728)
                     /locus_tag="ISD17_RS00145"
                     /old_locus_tag="ISD17_00140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231857.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
                     /protein_id="WP_000105985.1"
                     /translation="MSTLYKAMTRPAMYVGVPVVPLTVVAGALFLAGVYISKLIWLAIP
                     VAVFVLRMITKQDDHIFNLYFLKLKMLGNSVCNRFFGARAFLSGQYEAVEIDEFVNAMK
                     LNERITTGKYIPYSSHVDKNIVKTKNGDYVATWQLMGINFESISAEMLETIDSQVATLV
                     RSFSGLPVSFYNHSCRASFYDAFTTKSGNKYADIISDCYYGSMKKNKFKGNTLYFTLIY
                     RPDGRVEKLEKRKKSIKEKKDDINIHVKRMNEMINTFSGALDKFTCKLLGMYEENGKVF
                     SSQLSFYNYLLTGKLQKIRVTDSPVYNVLGGVDVFFNHDTGQICRIDGNKFFRSIEIKD
                     FCSETASGVFDVLQYSDADYIITHSYTSMSKSEALSTIKRAEKQLKSTEDDAVTQLQEL
                     EKAKNDIVSGDISFGYYHFTLMVMADSIRELDESVSKITADFTDLGIIPALSTMSLPAA
                     YFAQLPAVFHLRPRLSPVSNVNFVELASFHNFYQGKRDKNCWTEAVAILKTPSKQAYYL
                     NLHNSVLFKDETGEKNLANTKVIGTAGSGKTMFLSYLACSLQKYNNPETFADSAKNKKL
                     TCVFLDKDRGAELCIRMLGGEYYTVKSGEPTGWNPFALEATKRNRIFVKQLMEILCTRN
                     GERLSTRERLLISESVDAVMDFPPGEMREYGITRMLEHLMQRDDRDEQENGIILRLSQW
                     ANGQAHGWVFDNAKDTFNIQHVNNFGIDGTEFLDDPMVCAPITFYLLYRITQLLDGRRL
                     VIFLDEFWKWLQDEAFSDFVYNKLKTIRKLNGLVIPATQSPDEILKNKISRAVVEVCST
                     SIYLANPDADYNDYVEGLKLTPEEFNIVKNLDPMSRQFLIKKSSLKKGDGKSFSALATL
                     DLSGLGGYLKILSASADNLEIFESIYHEGMEPDDWVPEYLERAI"
                     /name="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
     gene            complement(25747..26073)
                     /locus_tag="ISD17_RS00150"
                     /old_locus_tag="ISD17_00145"
     CDS             complement(25747..26073)
                     /locus_tag="ISD17_RS00150"
                     /old_locus_tag="ISD17_00145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_000008647.1"
                     /translation="MSFKKSVCNRISSSVTAVMQRKNKVVMAVAGATVASPAFADGFSK
                     AETLLEKVKTGLSGLSLVTVTIACLWVGYKVLFGGSTIRECSPIIIGAIVIASAAEVAS
                     MMVN"
                     /name="TrbC/VirB2 family protein"
     gene            complement(26087..26707)
                     /locus_tag="ISD17_RS00155"
                     /old_locus_tag="ISD17_00150"
     CDS             complement(26087..26707)
                     /locus_tag="ISD17_RS00155"
                     /old_locus_tag="ISD17_00150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_000157549.1"
                     /translation="MASLFPALLLCAASVHPDTINDIARVESGFNPYAVAEIIPERERG
                     SYGKSVISHMPKSKEEALTVIREIENRKRRYSVGLMQITSSNFSFYSTSAEKLLDSCEN
                     LSVFEKIIVDCYKRGRSLENALSCYYTGNFSNGKRKEKEFNNTSYVERIGYTGNEKKYV
                     VPGTRSNGGEQRKNRSHNASVIWPETILKSAFVDNSHPTKVIN"
                     /name="lytic transglycosylase domain-containing protein"
     gene            complement(27063..27278)
                     /locus_tag="ISD17_RS00160"
                     /old_locus_tag="ISD17_00155"
     CDS             complement(27063..27278)
                     /locus_tag="ISD17_RS00160"
                     /old_locus_tag="ISD17_00155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="WP_000760375.1"
                     /translation="MKKYLLFALPFFVVGCSEEVKSVDWWGQHLTEAKQKQAECEKSGS
                     DSQNCKNVKQALFIQSQKDAPVPTFD"
                     /name="EexN family lipoprotein"
     gene            complement(27275..27568)
                     /locus_tag="ISD17_RS00165"
                     /old_locus_tag="ISD17_00160"
     CDS             complement(27275..27568)
                     /locus_tag="ISD17_RS00165"
                     /old_locus_tag="ISD17_00160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134733.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]; GO:0016987 - sigma factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="WP_000134733.1"
                     /translation="MTEHDAICISALHQIFSDEEHLSEQQKDIILMYAYGYTLNEIADF
                     KGLKPSTVRKYLDSVRAELGGVSLAGIRTLVLIRTNALLVSSLSRISERGNL"
                     /name="sigma factor-like helix-turn-helix DNA-binding
                     protein"
     gene            complement(27645..28874)
                     /gene="taxC"
                     /locus_tag="ISD17_RS00170"
                     /old_locus_tag="ISD17_00165"
     CDS             complement(27645..28874)
                     /gene="taxC"
                     /locus_tag="ISD17_RS00170"
                     /old_locus_tag="ISD17_00165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001329504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA relaxase/nickase TaxC"
                     /protein_id="WP_001329504.1"
                     /translation="MGVYVEQEYRIKRAKGTGRDPKSPKLSGRHIHASKSAFNHKVRHG
                     ADKKAYTWTPTKEVTFKITGSGKTAAGIKNGIDYITRNGELEAYCYDGKGSEQTGKGED
                     FNREFTSTLSKGNDYSRTYRGENIDHVKNMVFSPPPEAGVSREDALKATVEFLKETYPN
                     HAFVAVYHDDKEDHPHVHVNIKLRDEETGRRLRLTKSETRKFRNGFHRKLKGMGYDVTA
                     TWKKDPERKREIERLQAENPKRLRNVYKVVDFGETSYQNKAGEKRTPFLTYETLKGGKQ
                     VTIWGKDLKNHFESEKLQPGTLIKVKKLAPTLVRSPMFNDDGTVAGYRETHRNNWQIEN
                     IALERNRERQVHERETRQPEESDVKKQLSRKHEQGHNIGFALEHGFTKDSEEHKKLRIQ
                     QERNWKGLGF"
                     /name="taxC"
     gene            complement(28878..29381)
                     /gene="taxA"
                     /locus_tag="ISD17_RS00175"
                     /old_locus_tag="ISD17_00170"
     CDS             complement(28878..29381)
                     /gene="taxA"
                     /locus_tag="ISD17_RS00175"
                     /old_locus_tag="ISD17_00170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000781813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome-coupling protein TaxA"
                     /protein_id="WP_000781813.1"
                     /translation="MKMIAFRLSDDELKFAEHNAILSGFTSINAFAKHNVLNIETKPVN
                     IPVNNEPAKLVSVRLYPHEIELVKRNAALHGMSMSREIAIRVRQSLLKSEVCLYPDEVK
                     ELKKLSTAVDRVGRNIHFIIKGERFCTVNDPDFRKDVIEVIELCKQIDSKLETLTKSVV
                     NRFG"
                     /name="taxA"
     gene            complement(29742..30089)
                     /locus_tag="ISD17_RS00180"
                     /old_locus_tag="ISD17_00175"
     CDS             complement(29742..30089)
                     /locus_tag="ISD17_RS00180"
                     /old_locus_tag="ISD17_00175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="WP_000681613.1"
                     /translation="MKHLKYKGYLGTVEPDFENNVLYGKLAFIRDLVTYEASTLAELEQ
                     EFKTSVDLYLQSCVEDGKEPDTPFKGVFNVRLDPELHRRVAEMAMEEDLSLNAFVNKAL
                     EKEVSNHRAGA"
                     /name="type II toxin-antitoxin system HicB family
                     antitoxin"
     gene            complement(30086..30334)
                     /locus_tag="ISD17_RS00185"
                     /old_locus_tag="ISD17_00180"
     CDS             complement(30086..30334)
                     /locus_tag="ISD17_RS00185"
                     /old_locus_tag="ISD17_00180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005653200.1"
                     /GO_function="GO:0003729 - mRNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family toxin"
                     /protein_id="WP_000520549.1"
                     /translation="MGKTDKLLAKFLNSKKTFEWDELVVLFSSLGYVKKEMQGSRVRFF
                     NAEINHTILMHRPHPESYIKGGTLKAIKQNLKEAGLL"
                     /name="type II toxin-antitoxin system HicA family toxin"
     gene            complement(30639..30989)
                     /locus_tag="ISD17_RS00190"
                     /old_locus_tag="ISD17_00185"
     CDS             complement(30639..30989)
                     /locus_tag="ISD17_RS00190"
                     /old_locus_tag="ISD17_00185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000854261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000854259.1"
                     /translation="MKTLKQAAMQFASDLRNNRCFKAAYNDALLELDREDLNAIVQCTF
                     LFEPKRTLAELDKLIKKIEVEEDYEFCVSLDKGKGLHEVRTFKSEREALDAYRILTLYG
                     YTVTIEKKEGND"
                     /name="hypothetical protein"
     gene            complement(31080..31298)
                     /locus_tag="ISD17_RS00195"
                     /old_locus_tag="ISD17_00190"
     CDS             complement(31080..31298)
                     /locus_tag="ISD17_RS00195"
                     /old_locus_tag="ISD17_00190"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_005058042.1"
                     /translation="MHKDTGQQYVVIFTDNNKIRDYKAGIVPQFGELKQSDVDLVLFYR
                     DEYEKYFDSLKDGDECLSFKDFIECLC"
                     /name="hypothetical protein"
     gene            complement(31833..32060)
                     /locus_tag="ISD17_RS00200"
                     /old_locus_tag="ISD17_00195"
     CDS             complement(31833..32060)
                     /locus_tag="ISD17_RS00200"
                     /old_locus_tag="ISD17_00195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000801440.1"
                     /translation="MKPDNTPENVKKLRLKAGLTQKECSHIYGVGLRTWQKKEEVNTQN
                     SQSLSLVEFEFLLLLAGEHPEYVLCKRESK"
                     /name="hypothetical protein"
     gene            complement(32047..32298)
                     /locus_tag="ISD17_RS00205"
                     /old_locus_tag="ISD17_00200"
     CDS             complement(32047..32298)
                     /locus_tag="ISD17_RS00205"
                     /old_locus_tag="ISD17_00200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001565860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001230707.1"
                     /translation="MRKNKGDVTYFLEKEGDNYRLTKRIKARTNVKIGNKTTKITLYDA
                     VLNENELQHIDFTCAGLREDDETPVKNLIKEFMLNETR"
                     /name="hypothetical protein"
     gene            complement(32295..32837)
                     /locus_tag="ISD17_RS00210"
                     /old_locus_tag="ISD17_00205"
     CDS             complement(32295..32837)
                     /locus_tag="ISD17_RS00210"
                     /old_locus_tag="ISD17_00205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001083906.1"
                     /translation="MNSFFEQYHPVFEVVCRILGNGWRVNKLDDCSSRIKLTSPQFKNY
                     SVHIRMEKDRFSVVGSVDSRSWRSPHHVCTLSRKRNPVDIAADIERKILVNASQEVLQA
                     IEYEKHQVEKKDEILILKGMLSQLVQLESWYGALTGFKAENGLNGKVTEQGDSYDLQIR
                     GLSIDQLVKITGYLKQL"
                     /name="hypothetical protein"
     gene            complement(32942..33457)
                     /locus_tag="ISD17_RS00215"
                     /old_locus_tag="ISD17_00210"
     CDS             complement(32942..33457)
                     /locus_tag="ISD17_RS00215"
                     /old_locus_tag="ISD17_00210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025391.1"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="WP_001025395.1"
                     /translation="MNIQEALNVFGLSGELTEKDIKAAYRKAALKYHPDRNPLGAELMK
                     AVNAAFDVLMANIDKINQFQSTDEHARYNYGDDLEKVLNVLSGLSGLVFEVIGNWVWIS
                     GETITHKETLKEIGCKWAAKKKQWFYRPDEHKSYWNREEHTIEEIRAKYGTTGQRRATG
                     WQRVETRA"
                     /name="J domain-containing protein"
     ARG             3533..5154
                     /name="mcr-1.1"
                     /gene="mcr-1.1"
                     /gene_name="phosphoethanolamine--lipid A transferase
                     MCR-1.1"
                     /tool="amrfinderplus"
                     /drug_class="COLISTIN"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          1009..1880
                     /name="IncX4"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(27649..28874)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.511"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(15055..16913)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="98.71"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(19045..19949)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.669"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(19950..20632)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.4399999999999998e-137"
     Typing          complement(21175..22241)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.719"
                     /coverage="99.0"
                     /evalue="2.6999999999999997e-172"
ORIGIN
        1 tagcgaacta cgggcgcaat gcaggagaac taacagaacc tccctaaaac gctctgaatc
       61 gcattttaag cgattttttt catttcgcat ggttttcctc atggttgtat cgaacgaagc
      121 ggcagagcgc gattcagggc ttcttagtgg aagatccaaa aaggatcaaa taacggatca
      181 tatgatctga atctctctgg ttttgagaaa ggagataccg ctcgccgcag ccgaacggca
      241 ggagcgtagc gactgagtga gcgaggaagc ggaatttttg cgatgtgaca ttaggatcag
      301 tacgcacgaa tattatattt atttcaataa gttaaagtta actagggaca aatttatggt
      361 cttgaaaatt gagatacata aggcatcaaa tatttttttg atgattttat gttattgaaa
      421 gttatgagtt ttaatgattg atgatgtttg ttttagcttg cgggtaataa tcatcggggg
      481 acagatttat ggtaaggaac catcatcgtt gctggttttg ttgagttatc cacagttcct
      541 gaatattcgc acgcattaaa agccttatct tttcttgttt ttcttaaaaa cttaaaaact
      601 tagagtagct ctaatttatt gattttaagc gtgttttttg tctaaacatg agagcttcct
      661 cggttaaaca tgataacttc ctcggttaaa catgagagct tcctcggtta aacatgagag
      721 cttcctcggt taaacatgag agcttcctcg gttaaacatg agagcttcct cggtgatatc
      781 cacaaaatgt gtcataagaa tactaattcg ttgttctttc tggtgaatct attttgaatc
      841 tgttgttaat ctgccttgaa tccagtgtgg attttgagca tggattacct ttgtgagata
      901 aatcacagat atgaaacatg agaagatact cggttaaaca tgatattgat tgtgttgtaa
      961 tatcatgttt ctggtgttaa agtctgatta tcaagagtgt tggaacaatg agaatgacga
     1021 caaataagac ttccctttct cgcttaacaa aagtgagaca tcgaaatgaa ttgaattcaa
     1081 cgctgtcaac attgcctatg gctgctaaaa aagtcttatt tttagccatg tgccagataa
     1141 actctaaaaa tgaattcgat gatgatcaca tattttatgt gacagttgcc gattacatta
     1201 aatgggttca ggttaagcct gatgcggctt atcttgcttt gagggatggc tctaatatat
     1261 tagatacgac gcttcttaag ctgaaacatg atgaaatatt agaactgagt agtgatttgg
     1321 gatttaagtt cactaaaagt aatgtacctg attcaatgaa tttgagtctg actgtttttt
     1381 ctacttatta caggaatgaa ggtagagtgg ggatcaagtt tacgaaagaa gcgaaaagat
     1441 ttttatgtaa acttattggt gaagaaaaac gttatacaac gcaagtttta ttatctgttg
     1501 ttcgactgac aagtgttaat gctgcatcac tatatcaact cattcgtaaa atatatagta
     1561 ataattctcg cgcgaatagt tttgaaatga caatagatga acttaaagat gaattgaatc
     1621 tttatacaat aggggcgggg ggggtgaagg attataagta tccagattat cctgctttta
     1681 aaagagatgt tcttaataaa tcagtaaaag aaatcatgaa acatacggaa gtaaagaact
     1741 taagtttcgt agtttcagaa aaaattggga gaaaagttta taaattaaag ttctcttata
     1801 caattggtta tgagggcgat accagggaag actcagagtt tactaatatg tttgataaaa
     1861 tgtacccacc tgaaaattga ggtcataaca atatgaagga taatatcgta gattttcaaa
     1921 gaatcaggga cagcatgaat gatcattcaa ccgatgttgc aaatgatgcc gtttattctg
     1981 acaaaaagaa aatatccagg ttcttttatc tgctgacacc tgtcagatac cttctggctg
     2041 cttcccttta tctggttgtt gttattccat tggggattct tgcgggattt cgtttcttgt
     2101 tgcagttttt aggcggtatc gcagtgatgg gtttaactat cgcctggtac atgggtgcag
     2161 atgtcagtag ttacgttgtt cttgctgcat ggatcgcctt aactgtttgt ggttgcgcag
     2221 agcagatttt tgaatggtgg atcgaaagcc gttttgcgtt ccgtcttttt ggtatcggga
     2281 gaacgccgga agaatgagcg ccgatcttac agacagtaaa gaacaatgca ggatagacaa
     2341 tccgatgtca aatgttaaca tttgaatcag attgtccaaa aacgatgttt ttgcctgtgc
     2401 ctgccgcagg ctcttttaaa aggaatatga aatgatattt aaccgtaata aaaaacgaga
     2461 tgaacaacat aattctgctg ttgttttgcc atcagctgaa aatgtattct ctgattttat
     2521 taagaacaat ccagctttga caaccaatgc ttttacagcc attggggagg ttgattgttt
     2581 tactaaagta cccttactct caaataatga atcagagttt ttaggcattc tttcacgtaa
     2641 tattatacct gattattccg tttttcccaa aatacggctc attgaatttg ttcgtcctca
     2701 tggtagcgag gaagctgtaa aagatttaat ccgtgaagtg cagaatataa cctgtgattt
     2761 tgtcctgaaa tcatatgatg aaacagtcct ggctgttatc cagtttggtg aaaccgcaac
     2821 cgtcagacag caaaagaaaa aactgattat ccagcgcgtg tgtgctatga caggaatttc
     2881 ttttttcgaa tttaaaaaca ctgtcgatat gatggggagc gaagattttt gtcagttcct
     2941 gcgggatgat gaagagtaat taaaaataag cccacatatt tgcgggctta acaggctctt
     3001 tattagtact tgctgcattt gtgattactg gcaacacagt tttcactggg cagtttttgc
     3061 ggtcgctttt aattatggtt agtggaactc agacaggtaa ctcgacctct ttacatatta
     3121 ataattgata gttttacctg gcttccttca acatttattt tgttgaggaa tttatttaaa
     3181 tacgcaatat ctggagtgga accgcatatt ttcatcaatt cttgaccgat aggcgtaagt
     3241 aaagccgttc ctattggtag tttccaggtt gatgaatcat cgctttgaaa ctcaactgaa
     3301 aaaaccgttc cgtaataacc gatacgaccg tttttacttt taaagataca aattataaat
     3361 actctcaagt gtatattcag tatgggattg cgcaatgatt gcctaataaa atttctgaaa
     3421 tatttctgta tcgcataatt ttttatatca gataaattgt actggatttc ttaaaaaatt
     3481 gcagtataat tgccgcaatt atcccaccgt ttattttttg agtagtttct catgatgcag
     3541 catacttctg tgtggtatcg acgctcggtc agtccgtttg ttcttgtggc gagtgttgcc
     3601 gttttcttga ccgcgaccgc caatcttacc ttttttgata aaatcagcca aacctatccc
     3661 atcgcggaca atctcggctt tgtgctgacg atcgctgtcg tgctctttgg cgcgatgcta
     3721 ctgatcacca cgctgttatc atcgtatcgc tatgtgctaa agcctgtgtt gattttgcta
     3781 ttaatcatgg gcgcggtgac cagttatttt actgacactt atggcacggt ctatgatacg
     3841 accatgctcc aaaatgccct acagaccgac caagccgaga ccaaggatct attaaacgca
     3901 gcgtttatca tgcgtatcat tggtttgggt gtgctaccaa gtttgcttgt ggcttttgtt
     3961 aaggtggatt atccgacttg gggcaagggt ttgatgcgcc gattgggctt gatcgtggca
     4021 agtcttgcgc tgattttact gcctgtggtg gcgttcagca gtcattatgc cagtttcttt
     4081 cgcgtgcata agccgctgcg tagctatgtc aatccgatca tgccaatcta ctcggtgggt
     4141 aagcttgcca gtattgagta taaaaaagcc agtgcgccaa aagataccat ttatcacgcc
     4201 aaagacgcgg tacaagcaac caagcctgat atgcgtaagc cacgcctagt ggtgttcgtc
     4261 gtcggtgaga cggcacgcgc cgatcatgtc agcttcaatg gctatgagcg cgatactttc
     4321 ccacagcttg ccaagatcga tggcgtgacc aattttagca atgtcacatc gtgcggcaca
     4381 tcgacggcgt attctgtgcc gtgtatgttc agctatctgg gcgcggatga gtatgatgtc
     4441 gataccgcca aataccaaga aaatgtgctg gatacgctgg atcgcttggg cgtaagtatc
     4501 ttgtggcgtg ataataattc ggactcaaaa ggcgtgatgg ataagctgcc aaaagcgcaa
     4561 tttgccgatt ataaatccgc gaccaacaac gccatctgca acaccaatcc ttataacgaa
     4621 tgccgcgatg tcggtatgct cgttggctta gatgactttg tcgctgccaa taacggcaaa
     4681 gatatgctga tcatgctgca ccaaatgggc aatcacgggc ctgcgtattt taagcgatat
     4741 gatgaaaagt ttgccaaatt cacgccagtg tgtgaaggta atgagcttgc caagtgcgaa
     4801 catcagtcct tgatcaatgc ttatgacaat gccttgcttg ccaccgatga tttcatcgct
     4861 caaagtatcc agtggctgca gacgcacagc aatgcctatg atgtctcaat gctgtatgtc
     4921 agcgatcatg gcgaaagtct gggtgagaac ggtgtctatc tacatggtat gccaaatgcc
     4981 tttgcaccaa aagaacagcg cagtgtgcct gcatttttct ggacggataa gcaaactggc
     5041 atcacgccaa tggcaaccga taccgtcctg acccatgacg cgatcacgcc gacattatta
     5101 aagctgtttg atgtcaccgc ggacaaagtc aaagaccgca ccgcattcat ccgctgattt
     5161 ctccctgtat tttttccaaa cccaccgcac actccattcg tattatgggc ggtggggtgg
     5221 ggtttgttat gccgtattta tcaaataaac gcctacttgc tgagatgagt atcgctcttg
     5281 tcatggcgat cgttgccacg ctgacccttg agcacagtca gattgatctg atggtcgctg
     5341 attggtttta tctgggtatg gggcattgga tggttgccaa gcaagctttt ttgccagatt
     5401 tgctactgta ttctggacta aaaaagctgc tgatggcgat gctgatctac ttgctggttg
     5461 cgaccatttg ccgtgcttat catgagaaaa agggcaatgc tatcactgcc aagtggcttg
     5521 tcccagtgac aaaatttcgc gtgcgtgagc ttgcgtatct ggtgctgact ttgatcctag
     5581 tgccgacagt tgtcgcgtca ttgaaggcat atactcatgt ggtctgccct gtgcatttga
     5641 cgatttttga tggtacgctg ccgtatttgc cgatgcttga tagtatgcgt aacaccattc
     5701 ctgataagtg ctttcctgcg gcgcatgcca gtagcggatt tgcgctgttt gcctttgcgt
     5761 ttgcgccaag tttgcgccgc cgtcgtggtg cgatcatcat cgtggtgatg gcattgggct
     5821 gggcgatggg ctgctataag atgattattg gcgatcattt tttgagccat acggtggtgt
     5881 cgatgatgct tgcgtgggcg atgtcggcag ggcttgcgtg ggtgtttttt aagaagggtg
     5941 aacaatcaag aggttaaact ataaccaatg ccttgttgaa taacgcctaa ggagtctaaa
     6001 accgaaagtt tatcgaaagt tataccttca gtatctccat tctcatcggt aaataaaatt
     6061 ggagtgagtt tgtttgcctg ccaaacaaac tttccaaaat aagtaataag gttcgcttct
     6121 tctttgctta tagtggataa tagttttaag gttctacgac taaacgaacc ttttgacttt
     6181 gcttcttcgg ataaaattct tccccaaagc atttgcattt gttcgtcact aatatcctca
     6241 cactccctga agaaagcctc tatccaatct tcgtcaatat cagaaacatt atcactctca
     6301 gatagacttt gtgctgcttg cattgttata ttttcaatgt tttcctgtcg tttcgtttca
     6361 cgtttgagaa aacgctcaac tgcccgtttt tctattccct caagctctaa cctagaaatt
     6421 agctctgtgc gtttagcttc agcttcagcc ttcgcttttt tcctgattct tgtaggttca
     6481 taaagcacac caatagcatc acttattttt tcaataagtt ttgttcctgg ttctgataat
     6541 cctgataaac ttaaatcgat aaggctcatc tagtgctcct aaatacccgt gcaacaactg
     6601 tacaagggta ttttattgca agagtaacta aaaatgaatc acaactacat ttaaaagtga
     6661 tgaagttagt acattcagat aagtatctaa aagaaaatga taaagagttt attgggccac
     6721 ttgctatgat taatcatttc tgtcagctct gaaccacaaa ttaatgagtt cgttttcgtc
     6781 cagatcctga taagccagta atgctgcttt gattattttt gtcttgggac gatgcagtct
     6841 tttcgattcg ttatcaatga attcaagcaa ttcattcggt atgcggaatg aagccagttt
     6901 tgttttgttc tctgtggggc gttttcctgc gtcctgaaca aattttgtgg cgttcacttc
     6961 ctggttttgt tctagttctg gtagttccag ctttgccatg atgtaccttc taatctgatt
     7021 gtttcacact aatgtatatc atgatgatgt acattagtgt atgtcactat gatttacagt
     7081 tccagttctt tcagcaagag ttcgatttgt gcttttgcct ggctggcacc gctaacatta
     7141 ctttttaact cgtgaacccc cattccctga ttcattgctc ttacaaaggc ccggagaaaa
     7201 gaaaccgtgc ttttcattgg tttaagccag taatcatggc tgttgagaga gtctcttaat
     7261 tcttgttgtt cactgaacgt atttggctgg catttataca ggagcacatg tgcagccagc
     7321 ctgggattta ttttttgcgc atccctgaca atttttgtca cagtctgaag actgtctgct
     7381 tccacctggg caagcgggtc gatcgggaca atcacaatgt ctgcaacttt tagtgcagtt
     7441 ctgaactccg tgctgtcata tccggcagta tctataatga ggatttctgc tacatctgcc
     7501 atttttgtta ttttggcact gatgtcgcca taggcttcat ttaatgcgac gggcggtaat
     7561 ccggcctgtt ctctgcgttt attccatttt ttggtcgagc cattcaggtc tgtttcaaca
     7621 agccccgttc tctttccctg ttgtgagagg caaacagtta agttggttgc cagatgtgat
     7681 ttacctgtac cgcctttatc accaccgatt acgataatca tagtacccct tgtatgtcac
     7741 agtgatttac tcatgtgtat ttctatgtga tgtacgcatg cgtatgtcac atggacatac
     7801 tatagtgtat gtcacaatga attacaatga tgtacatcat gaagaaatac attattgtat
     7861 gtcagtgtga tgtacccgtt ggttggtcac ttgaaagcaa aagtgacagc gttactttcg
     7921 gtatcctccc ttgctgcgaa accttgtggc aatacagcaa tgagtatgtt tagttacaac
     7981 attcaaaatt aagcgattag attccgcccg tacgggcggg gcgcgccact ttctgtagtg
     8041 gggaggggca gggaggttat gtttgctgga tgagcggagg atggaatgag ctattagaat
     8101 gttgtaacta aagggtatcc caattaaagg ccacttacgc ggcctttgtc tgtcggttct
     8161 tcggtctggt gacataccac gataaacatc ccacagcaac actcataagc attccggata
     8221 agcgatcatc gatgccagga aacaggcaac cgacaaacat cgcaacaggg aaaggaagaa
     8281 gtaaacagcg ccccaaaatg ctcataaaat ccataaatcc tccttttttg ttaaagggca
     8341 ggaagcggtt cacttcctgc ccttagttac gtttccgttg tcatcaatcg atgaattggc
     8401 ggatcagttc cagaactgca atcagcgcgt ttgcaacggc gaccacagct ctgagaacga
     8461 tgattaacat attaatcatc cgtttctcca gtaaaactgg aggaaatcac cgttgcttgc
     8521 tcatacactg cctgtcacaa cggctctctc gcattgttag gtgtagagtg acctcctcct
     8581 gccagagcac cgaatacagc accacctgtt tatccagcca ggactttaaa atcgttcata
     8641 cccgcagata cgggaacagc aggattgcaa gccaactaca tgactaactg actgattata
     8701 cgctacacaa aacacccgtt acaccactaa atgtggttcc ttaaccacat ttagttgctt
     8761 tacagcacca tagtgaataa aatgtaaacg ttaggtgtag agtaaccttc tccggtcaga
     8821 gccaccaact caagactgga aaacgcaaaa aagcccgatt accagtcggg tttttttgtg
     8881 cctgtcgttc ggctgtagtt ccgttttttc tccttcattt gagggatttt tctttcattt
     8941 tttttgttgc ttccaatact gcctgtcgcg ttggccaaca gcttgacgcg ttaccggcat
     9001 tttcattact caatattttt cagtgaatta aaatgcaaca gcgacagaaa aggacattca
     9061 gctttttaga tgaatgctat agcaacggtg tgctacgtaa aatctgcgaa aaaagcaggg
     9121 gtagggtagg ttatttttca cgtagcaacg ccatctggca ctgtacatag gtatgtcaca
     9181 cagacatacc tatgtgtatg tctgtgtgat gtatacctgg cgggttattc tgcctgttcc
     9241 ggcttagttt tctcaatgag gaaatcttcc atgaaatgcc cctcatcaag cagcttctgt
     9301 aaagcaagcg gacgcttgcc attaccagac cattctctga tctcgccatt ttcatcctta
     9361 aagcggtatt tagcctttct tactccgcct ttggctttcc gcctggtttt tactgtatct
     9421 gctgttacag gagcaaggag tgattcggga tcaagaccta aagatatgat gtattcaatg
     9481 gcctgctgac gtttggcttc aagttcctgg cgttcagccg cttcacgttc agcatcttca
     9541 cgacgttctt caataacaac gttgagcttt tcctgcattt cgagcaactg ctcaaaatca
     9601 atctcacggg caaaaacacg caatgaacga atattcatca tagtacggct gataatgccg
     9661 tattcatctt ctttagtcag ttcgctcata taattaatcc tcttatttag tgtacgtact
     9721 tccagacgcc ggaaggcacc ttatcataaa gtttattcat caccagttct gctcggcgat
     9781 gatctgcggc agaataaaat gcctctgatt ctgataaagg cagtttgtaa cggttaatct
     9841 caataacttt ttcaagagta tctcttgatg tacattttct taactgaaaa agccattcct
     9901 gctttgtttt cacttcttag cccttgccgg aaaacccagc ttccctgttt tcttatcctc
     9961 aaggacaaga actgtatcat acgttccacc acttttcttt ttaaatccct taatcaaatc
    10021 ggttttccct gatttaacca gtttttcggc ctgtgcctgg gtgattttct taccagaaaa
    10081 ctcactccag attttaaatt cacatccggt acagaaataa cctttcggcc tgataacaat
    10141 atgtttacca caggaagggc agggagagtc caggcgttga aactgccctg ctggcgcagc
    10201 gggttcaatc ttcatctcgc ccaggtcaac atcagaaatc atgcctgtca gttcaccgta
    10261 cagatcatta ataaactgtt caaccgtcag gtcgccattt tctatggcag cctgcttttc
    10321 agaccataat gctgtcatat caggattaac cgctatacca ggcagggcat caataagcgc
    10381 atatccggta tcagtaggaa taagtttccc tttttccagc gtgatatagt ttcttttctt
    10441 cagcgtttcc agaatggctg cgcgggtagc tggcgtacca atgccaccat gttcatcttt
    10501 tttgtcttta tccttatcct tcaacaattt tttaattgtt ggatcagtga caaaatccgc
    10561 gacacgaaca agcgcagcaa gcaaggaggc ttcggtgaat aacggcggcg gtgttgtttt
    10621 cttctcatta acaataactt cttttgtcgt cagtgtttct cctgtgcgaa ttttacagag
    10681 cagttcaaaa gcggaatcat cattatcttc tgattcacct tcgtctgtgg tttccgcgcc
    10741 aagaaacgcc tcaaatccgc tgtcagttgt ttttctggca cgggcataga acgactcatc
    10801 accacactga atggcaaccg atacttcctg gtatgctttt tcaggcatga actgaacaag
    10861 atagtgttgt gcgatcgcca ggtaaacatt gcgctcgtcg gtgctgagtg cgttaacatc
    10921 aggcacactg gcggtcggga ttatcgcagt atgcgcagtc acctttgcac tgttaaacgc
    10981 tttgctttta cgtgcagaat caatatccag cgactgagga aagactgatt tcagggcatc
    11041 gataacctgc ggcgcttcgc tgaattgttc atctgaaaga tatgagcagt cagagcggtt
    11101 atacgtaatt gctttatatt tttcgcgtag ttgttgcgta atatccagcg ttttttgtgc
    11161 cgtcatttta aacttcttgt tcatgtattg ctggagtctg accagattaa acggcaacgg
    11221 cgcagccgtt tttttatcat cagttgctgc tgcttcaact gtagccggtt ttcctgcaag
    11281 ggatgcagcc gttccgtctg cccacgcttt atcaagtaat ttacggtctg tcagcggagc
    11341 aaattcccct ggcttccagt tcgccctgat aacatcagca ccacgctgaa agactccggt
    11401 catggtgtag taaaaactgg atttatggtt ctggttagca cgggtacgat tcacaatcag
    11461 gccaagaacg ggagtctgga cgcgcccgac agacagaacg ccctgatatc ctctggcttt
    11521 tgcaggaatg gtgtaagcac gcgtcatgga gaagccatag acggcatcag caactgaacg
    11581 cgccagcgcc ttaaggtaaa gccctttgaa atcacgatta tctttaagat ttgccagtgc
    11641 ctttttcact gccggaagcg tgttgtcgtt aatcagaacg cgctttacgg gttttgtgtt
    11701 tcctgcatat tccaggactt catcaacaag tagctgtccc tcatcatcag gatcgccagc
    11761 gtgaacaatt tcagtcacgt ctccacgtct gataagctcg agaatcgttt taacctgttt
    11821 tgctgcactt tcaacaggct gatacttcac gggataaaga cgtaaaggaa gcgtttcaac
    11881 cttccaggct ttgtattcag gattatagtt ttccggcggc tgtgattcga taatatgacc
    11941 aaaacagtta gtcacaatgg cgttatcact ttcaaaccag ccatcatggc gggtaaaatt
    12001 gccaccaagt gccttaacaa tatcatttgc tactgcgggt ttttctgcga taaaaagtct
    12061 cattttgtta tcctttacat tgaattaatc tgtttgcaca acgaatagcg cgttcttctg
    12121 atactgcctg ttgccagtta tcttcactta caggttgtct gaatctgcgc tcacagccat
    12181 taaaggcaaa aattccctca cggttaagta tattcgttgc gatatcctgg tctttaattc
    12241 tcaaaaaagc tgttacagca aaaccagaat atgaagcaat ttttgaaatg atgcattcat
    12301 cagcttttat taatgcggca aaaggaacta tcttttgatg tccacacaaa atcaaaggga
    12361 gggtgtgaat atcataataa gctattgaat gacaatccat gcgggtatca tcaatagctg
    12421 ccagccagaa tcctgtctgg tcttttattt ttctgctaat atctgaatct gaaacaccag
    12481 gatttaataa atatccacca tagcagacat ggaaggggtg aacagattca tcaatatcag
    12541 gaagttcttt taccggattt tctttccagt ccttcagaac accaaattca agagcatcca
    12601 gcaaaaattt tcgttccagc gcatcaacta atgcatattg cataataacc accaaagagt
    12661 atctgattta tataactaat gcactttcaa tagatggttg tcttttgaat aaagaacaat
    12721 ctgtattatg actgtgaagt attcagcatt agtattcatc ttcataaggt agccaatcgt
    12781 aatcgtttga gttccagtca attggaagaa atggctctgt ttgtttatgg caggagaggc
    12841 aaacataaat atttttctct ttatgaaaaa tcatcgactt acatttatca cagtcgcacc
    12901 aaccctcgac tggttcaggg cattcaggta attctgtctc ctgatgttta ccatattttt
    12961 cccattcctc ggcatcctga taacctcccc atactgcttg tgtaaaacta tcgatatagt
    13021 cacctgactc atttttatca aaattaaatt tatatacttc gccatttagt tcaaatgaca
    13081 tatcaaggtc aggtagtaat tgcttttcga agcgttgttg taactctttc ttttctttgg
    13141 gtgataaagc cataaaaacc tctatcagtt agttatgttt gtatcgccat tcccacggtg
    13201 gaaccggatt tgcatcggcc cacaaaccgc gtttttgttc ctgcgcttcc cgttgcagag
    13261 ccggtaatga ctcatccacg ttgtaacgtt catataccca tgcagcgcca gactgaacca
    13321 taaagcggct ggcatccgtg ccgttcgtcg tgaacacatg accgataatg cgtccgtagc
    13381 ggtctttatg tgaataagag actgtcacct gtttacctgc aaccagagtt ttaagctgac
    13441 tagttgacca gcgtccaaaa ggttgtttct tttcaggggc atcgatgttt atcaatcgga
    13501 ctcggatcgg aacttcatac acaacaattt ttgcgggtag tgttttaatt tctatggtgt
    13561 cgccatcgag aacgcgaata actttcccct ggatttcagc cgcacacaat gtagctggta
    13621 acagggaaac aacaaaggaa agagccttaa gaaaatgtct cattgctttc ttccctccca
    13681 tattgctgag agtattttac aaatggataa aacggcgatt aaagccactg cgataacagc
    13741 caacgaagga agtacatagc tatacaactc aactatgaaa ttaagaaatt ccatgagcga
    13801 ttgcggcttt aaaggatcat cccataaaac gataacaaca cgataaagcc catagacaat
    13861 tgccgaaaac cagaccataa acagtaaggt ttcagtaaaa acaaaagcga ccgttttaac
    13921 actatcgata atttcaattc cggcaactct cacacttctt gctttcatat acacctcatg
    13981 gattacgagg aaactaacgc ccttcggttg ttcaaccccg caaatcccgg attaaaatcc
    14041 ggaatctgcg gcgtttgccg ttatctccgt tcagaataac tctggataaa ttttaaactc
    14101 attaatttct tcaactgaaa tacgctctgg catagtcctc gaacaatact ttgtgagagg
    14161 agtttctttg cagttacctg ctttaccgag cacaatcgtt gccacgtagt tatgaatgat
    14221 ggcgttcata gtcttatcat ccagtgcatg agcaggatta ccagctattg agccagagtg
    14281 tcctgtcttg attacattca gtaaatcagt agtttgcttt tccatatcat ctacccttta
    14341 accttgccga acttactcat gatttttgat atagcagcag gatcagccgt tgaacactga
    14401 ttcagaaatg ctttacgggc atcaaaagtt ttactccagc gaatgcttcc ttttttcttt
    14461 ttcagaatat taaaaaaatc cttttcagca cttctgcatt cactccctcc accttgcccg
    14521 actgcttttc catataagca aagtaccgaa gcgcaagggt cagatgcatt agcatttgtt
    14581 gatattaatc ctaacgccag caaggctggt aaaaccactc tattttttcc agtcattttt
    14641 cacctcattt tgtgctttaa tgaaaactat ttttacctgt tcaggtaaaa aacttttctc
    14701 gtttcgccat tccacgactg ctgttgcccc ttccatcttc aacagatctc tgattcgaaa
    14761 ccacagccca gcatcatgtg ttgtcactac aatcctgtcc gcatgagcca gagcgtaata
    14821 aaacgtcggc gttctggcct gtactccgga taaggaagtg atctcataaa cccatccttt
    14881 accgctaacg tctgacttta tgacaccgtg aaaatcgggg acatatggca atgagggatt
    14941 gatcacttca tttgcctttt caaactgcac gggtgttggc tctggcggtg atgaacaacc
    15001 agcaagaatg gaaatcaata aaaacactaa cttcttcatc atgttctcct ttatgccgct
    15061 ttatcgagat caggaacatc ttttactacc agataccctt ttgcgacgat ttcattttca
    15121 aatactttct gtggaggcat aaccagcttt cctttcttcc tggggaaaat gtttgcaagt
    15181 tccggagcaa ccttcacaaa gtcaccaaag aaatactcat tgagatagta gaatgccttt
    15241 tcacaacgaa tcgggttttc tcccttcatt gccaggattt cttcactaaa tttcagtgta
    15301 agtagttcat ttgttgttac cagtggacgc tcaataaggc tttctgattc agatctcgat
    15361 gttcctccac gactacgact tttgcttttc gaaccgatag ttactgttcg tgtccccatc
    15421 gcttctgata actcccgcgc atctttaaca tcagaagcgg aataaacaat tttgcagggt
    15481 gcacttgcca gtaatgtttt actgcctgca taactgtaga tttcctcaag ctgagagccg
    15541 acctggtaaa caatcaacaa tttcagcttg taaccagcaa tgagaccaga tttactcttg
    15601 atgtaatcta cagcaccaat tgacgggaat tcatccagta gaaaaaggca gtcatgcttt
    15661 atttccggat catccgttgg catcttttca agattcacct gtatagcaag ctgaaagaaa
    15721 atatttgtta ttttttcagc caacctggca ttatcaccag aaatacagaa ataaattgtc
    15781 atccgctttt tccgcacctg ccgcaaatca aaatcatttc catcagtagc atttgccaca
    15841 ttggggttag caaacggtga taatccatta agaaagttgc ttttgagttg tgcttttgtt
    15901 ttatcctcca tctcaatgaa tgccttaagg ccagcgacac caatatcagc aagcgttttg
    15961 tctttccccc ttaattctga acgaatatca ttcatgaatg aaagaagatg ttcgggttct
    16021 gcacgctcaa aaagctgatt aattttagac attgagaaga caggctcaat atcaagcgtt
    16081 tttagtccag ccttatcatt cttaatcata aaccataaag cgacagcata agatttaaaa
    16141 acaccacccg ccgtcttatt aagatagcta ccagcatccg caccatctgt cttatagggg
    16201 taaataatca acgaaagatt ttcaagctga ttaaaacctt cactcgttcc catgctgaca
    16261 taatacaaag ggttaaagcg gtgcgttacc gaactaaagg gatcaaattt ataaacctca
    16321 tgacctaaaa tcaccttcct gataagactg gtgatattaa aacactccct ttttggatcg
    16381 agaataataa cactccacca gtacttcata agattagtga tgactatacc agcaccttta
    16441 ccagcccttg ttccggctcc catagcactg aatgctgctc ccacatagcg tatgattttc
    16501 ttgtctttta taccaacgat aatcccgtct ttttcgtcac cgtcaagcgt gaaactgtta
    16561 gactcacgaa tatcattaat tgttgcaaat cgcgcatcac cgaaaatatt ttctttcttc
    16621 tcgttcagtt ttatcaacgc cgcaacaggg atgataagag acacgacaaa tcctgctcca
    16681 agtgcaacaa aggctaaaac tctgatatcc gtagtcacaa cagataaagt aaggctgtct
    16741 gtaaaaatat ccatcctgta cgcatcaatg gatctgaaca cagccttcaa tggtttcaga
    16801 ttctttatct ggctgaagta aagcacaaag aaaataaatg aacctgcaaa ccatgccgca
    16861 acaagcataa cagcgaatat aaaaacagat tgcgacttat taaaagtttt cacattcagc
    16921 ccctttgtaa tagatgtcgc tcatatgcct gacaacacca tccctgccta catgaacaac
    16981 aatatcaata ctgtccataa tgattttacg aagaacatca aaaggaagat tctgacattc
    17041 tctgttctga taacattttg tcaccatctg aatgatggca tcttttgccg aggccgcgtg
    17101 aatggacgtc atgcttccac tgtgaccaga accagcaact ttcacaaaat cccaggcatc
    17161 gccaccttta atttccgcca gtaaaattct gtcaggtttc atcctcaaac aggatttgat
    17221 taatttcgct gctgttatga tagagccgga atcactgccg gattccgaag ggtaaaaaag
    17281 atgcacataa tttttatgga taaaaaattt gatttcctct gcatcttcaa tcgtaatcag
    17341 ccgtgtattc aatggtatga aatcgataag actcttcata taagttgttt taccggaacc
    17401 cgttgctccg gcaaatacaa tggttttccc tgctgctacg gcaagctcca taaaagcagc
    17461 gatatttctc gctctgaata aatcaagaag ctcatcatcg tatgtcctgt gtttttttcc
    17521 tgactggaca taatcataaa aaccgttcgc cacatattct ttatgtgtta tctgccgtgt
    17581 cgatggttta cgtatagtga ttgaaatagt atttctctca catgcaggag gaaaaacgac
    17641 ctgtacacgt tctcctgatt ccagtgttgc tgaaagtaat ggcttggtct cgccgatttc
    17701 atctccccga aatgatgcca gcgtatgaga aaaacgttta caaaaatcaa aggtcacact
    17761 gttattatta tggaatgtcc agtcaccatt aatttccgtc cagatttcac caggacggtt
    17821 gacagcaatt tctgttagcc cttcaatatc aagaaaagac tggaatactt gatttttata
    17881 aaaatcgagc gatttattgc taatgctgac aggaataacg ccactcatac tattttacct
    17941 ttaactcata gatatcagaa aaatcaatgt cttccccgac cataatagtg attatgtcac
    18001 cctggttttt atacattgtt ggaggaatat ttatcgaatt ctcaagtgcg actttagcca
    18061 tttcagccat tgcctgtcgt gagttttcgg tataatccac attacgatct ttaccaggtg
    18121 cattatccgc cgccgccgcc gctacatcct gaaccatact gagcataaga gaaccaccaa
    18181 aacgctccca gaagtgagaa tcgatccatc catcaatgcc cgcttctccc aggggaccag
    18241 ctgctgctgt atttaccata tcgattcgtt tattatcagg cgtccgcaac tgctcccaca
    18301 taacgaacat tctgccctgt ccatgattca gcgttccggt ctggtaacga ccaaaagcct
    18361 tagttccctg ttccagtaat tttgtgtggt gattagcact ccatacatct tctgtaaaaa
    18421 cacaactgat acgacctgca acatcagaaa caaagcgtgt ggttaaagca cacggtataa
    18481 gcctgttttc ctcaatatag agatcaggat cgagattaat cgcagttact ttcattcctg
    18541 atttaccagg cacattttct tttgattctt tcctttcttc ctgtggctct gatgtctgcg
    18601 atgtcctgct gctgccactc gcgccagtct gactccctcc ctgaccagca acaggtattg
    18661 acaaatattt cctgaacccc tcctgtggca cttctttatg accgtcagaa acagtattac
    18721 cagaaccagt agcgcctgga ttgataattg ctttgttctc aacagggtca aaattctgac
    18781 caagaccagt acggatttta cttacctgag aaatgctggt atcgcctgtt gattctgatg
    18841 ctttctgctg gtcatctgca aaataatttt tatatgtttt cagcgcaaaa ataccaataa
    18901 ctaatacagc catcagacca aacagaaagc cagaacgcat acgattattt ttgttcctga
    18961 tatcaccgat atcatgaacg ggtttacttt ccagctttga ctgattcgca tcatcaacta
    19021 aatcatctgt ttttttcata tcagtcatta ttcacctcaa cacgttctac cgcaggagaa
    19081 gacgtattcc tctggtcggt taatactttt ccgaaagatt tattcacaac accaacaacg
    19141 ctgtttccat agcgtaaaac aaatttgtca ttaacgttgt ggataaccat aattttatac
    19201 ttgccttttg tttccacatt aaaagcaagt gtctgttcct gaccatctct tacagcaaat
    19261 ggagctggga atactttccc tgagttaaaa cctaaaaagg taaatatgcc attatcataa
    19321 gcaaaatcag gggcgatacg acgactgtca tatttttcat tgactcgcat gaaataattc
    19381 cagtttttag gcgcatcggc tttttcaaaa ctttcagaaa tcagtttctt ctgtctgagt
    19441 ttttcctgtt tttcttttgc cagccttact tcttctgcat tctttttcgc tatttctgat
    19501 ggatagcgga attgtacaac ataagcaggt tgcgcttgtt tttcttctga cagaaggatt
    19561 agatccagac tgtaaatccg ctttgttgtt ctgacaaaaa gattcgtatc ccattccttt
    19621 tctgttggct ggaaaacctt tttcagtttt tcgccttcat cgccttcctg ttcctgaaca
    19681 acgggacgcg gattgatgta aacaacatta tcatcggttg tgatttccca tccggcagga
    19741 aaaccagcct ttgcactgat aacagcctca ccttcatcaa aaacaactga tgtgagaaat
    19801 cctgtctttg accggataac ggtcgtattc gcaccgttat aactcacagt ctgcatcctt
    19861 gcatcaaatc cagaaggtaa cggagtcgct gctgaataca caagcccagg aagcaataaa
    19921 catgtagcaa taaataattt cttcatcatt cccccctgac ttcccgatct gtctggtaac
    19981 tggttacagt aaaaccgaga ggattaagct cacgactgga acttttaacc gacttttctg
    20041 gttcaaaacg atatgtcaca cgagccgtcc agtatgaaac tgaaacctgt ccggtcgtga
    20101 agtttctcgt cgttttttta aagcgcacag aggccagttt atctggcgcg gttgcgtcag
    20161 aaataatatt ggagatgacc tcaaccgcaa cgtaagaacc gttattatga taaattttat
    20221 caggagccat atcgctgtta tacagacgaa gataatcgtc ctttactgta ttcgagctat
    20281 atagctgtac agtctcataa tcatactgaa gagacggata attataacct tcacgtaaag
    20341 taatatacgt gtttacaaaa taccgcccaa gtgcttcaga ttgcaggatc ttttcctgtt
    20401 taacctgagt aatcagttct gtacggcctg ttttttcgcc aacagccaca atagcaagct
    20461 ctttttcttt taatggcaca agaacacaaa ttgcagcccc aagacataag gacagtaatg
    20521 atgctgccac tgcaacacgc catgcatttt tcttagaccg ttcattttct gcatagagtt
    20581 gtctttcgaa ggatttagct gtctcaatct tcttttcgat tttttcactc ataactgatt
    20641 acctggctgt ggttaatggg ttccagttcg ccggaaacat cagaaggaag gttattcctt
    20701 gtggtacatc cggaaatctg aaacaggaaa aacaaaagaa tcacacatcg cataaattca
    20761 ccttattaag cgttcacgaa cacctttaag agataaaggc caagatgaag aaaaagaatc
    20821 ccaccaataa gaagcaaaaa gcgaagatcc ataccctttc tccatttccc cgcaagccct
    20881 aaaccaagtc ttattcctgc gaagcaggta aacactccta aaagaaggat taggacaaaa
    20941 taaagtatca tgacaaaata atgaagcatg tcacaaccag ctctgactga ttccacctaa
    21001 gaccttaaat aaggtaattc ccgtgattaa aataacaagc tgggttatta gctttctctt
    21061 cctgctccat ccggaggtga tatgtttatc aacgaacacc agtatccagt tcagggacat
    21121 cacataaaaa aaacgtttca ttattttcat gcggcgttcc tcgctcgtgc tttttccagg
    21181 gatgcaagtc ttctcgcctt catccccaaa gcacctgtcg gagccagcgc ctgatatccc
    21241 ttttcacccg cccattcagc ggctgttcgc gcaccacgcc ccatcagatt ccctgctttc
    21301 cctgataaag aattcatgcc cgttcttccg gccatcccta agccaaaacc taaaccagca
    21361 cgaccgccaa gcatcagaga cttaccagta gccataccag cagcacccag ccccatcatg
    21421 gctgcgccct gaacagcacc ttcaacacct gcacctgcta actggacagc aaaaccttta
    21481 gctataagaa ccaataaagc ccccaaaaac ccagccataa agcccatagc acctgtagat
    21541 acaagattta cattccctgt ttgtgcagca cgaatagcat gggaaaggat catcccttga
    21601 aaatccattg ctatccgaat cactaaactg gcaaatagaa ctgtcagaat actggagaat
    21661 aacgattgta accaattatt aaacatgctc cgaataaaac caaacatgag acaaaagata
    21721 aatatcggtg ctgtaataat caggagtttc atcgttacat ctgctgttaa aaaaacaacc
    21781 acactaacag ccattaaaat aagcgagcca gtccatatta aaaactgacc aactacacct
    21841 tgatctttaa catatgttga tttatctaaa gagtatattt ccgcaccaag attttgcgta
    21901 cttttccata agttatctaa agtttgccag acactcaccc ctccagaaaa accatctttc
    21961 atgccttgca acgcatcagt agccgcagtt aaatacccat ccgcattagt tataaacatg
    22021 attatgattg caaattttga tagatcccat actaaatcct gcaagggcgt ctgagtttta
    22081 ctggcaagta tttgatatcc tttccatagt acatataacg taaccgatac cgtcgctaac
    22141 gacataatat cattagcaaa ttgtgtttga taactggagc tgattttatc taccgaatcc
    22201 ataacggtag aattatattt aacgaaaaac ccctgagcca tatatccacc ttttaatcaa
    22261 aagttaatgg ttcagcttct ttctgctgtt taataaaggc ctcttgttct tgtgtgacca
    22321 acatctcatg atctgcttta tttttattat tccagacatc atactgcatt tttatcgcct
    22381 gcatttttaa cgactgcgcc tgtaatgcgt tagccaaatc ctgggattct ttgatatcct
    22441 ttgaagcctc aattcggcta cttaaactct gaatctgaga cattgcactt gataactgct
    22501 tattgatctc atttccctgt tcaatactgg cagccgttga cacaatccgt gctttacaga
    22561 gattatcatt acgttcatag cccgtattac acatatcgaa ggctccatac ttgctgaaca
    22621 gatttttagc ctggctgctc aatgcacctt cgggattact ggtaaaatca gaaatataac
    22681 tgttcccctg cttataaata tttgtcagtt ctgattgtag attacttagt tcatttgtga
    22741 atgccgcaat attccttata cctgttgccg tggctaactg gtctttatat gcctgaatct
    22801 gactctgata atgttgcgca gtttcggacc attgtttgag tcgttctgtc catcttgcgg
    22861 cttcaacagc ccattccgga ctggcatcaa tagcaaccgg aattcctgcg ctactataaa
    22921 atgaagccgt caataatgat atcagcatca atgtttttac acgtttcata aattcacctg
    22981 tcagattgcc cgttcgagat attcaggaac ccagtcatca ggctccattc cttcatgata
    23041 aatactttca aaaatttcca gattatctgc actggcagac aatattttca gatatccacc
    23101 aagtcccgat aaatcgagtg tcgcaagtgc tgaaaatgat ttaccatccc cctttttaag
    23161 actgcttttt ttaatcagga actgtctcga cattggatca agatttttaa caatattaaa
    23221 ttcttctggt gtcagcttaa gcccttccac ataatcattg taatcggcat cagggttagc
    23281 cagataaata ctggtgctgc atacttcaac cacagcccgt gaaatcttat tcttcagtat
    23341 ttcatccgga gactgagttg ccggaataac cagcccgttc agcttacgaa ttgttttcag
    23401 cttgttatag acaaagtcgc tgaatgcttc atcctgtagc catttccaga actcatccag
    23461 gaagataaca agacgccgac cgtccagaag ctgcgtaatg cgatacagca gatagaaagt
    23521 aattggtgca cataccatcg gatcatcaag aaactcggtg ccatcaatgc caaaattatt
    23581 gacatgctga atattgaatg tgtctttagc attatcaaaa acccagccat gagcctgacc
    23641 attagcccat tgggacaaac gaaggataat cccgttctcc tgctcatccc gatcatctct
    23701 ctgcataaga tgctcaagca ttctggtaat gccatattcc cgcatttcgc caggaggaaa
    23761 atccatcaca gcatcaacac tttcgctaat aagcaatctt tctcttgtcg ataatctttc
    23821 accatttctg gtacacagaa tctccatcag ttgcttgaca aaaatacggt tacgttttgt
    23881 tgcctccaga gcaaaaggat tccatcctgt cggctcaccg ctttttacgg tgtaatattc
    23941 cccaccaagc attcggatac ataattcagc ccctctgtcc ttatcaagaa agacacacgt
    24001 taacttctta ttttttgcag aatcagcaaa agtttcgggg ttattgtatt tctgtaatga
    24061 acaggcaaga tatgacagaa acattgtctt acctgaaccc gccgttccta taactttagt
    24121 attagcaaga ttcttttcac ctgtttcatc tttaaacagt actgagttat gtaaattcag
    24181 ataatacgcc tgtttgcttg gtgttttgag aatagcaacc gcttctgtcc agcagttttt
    24241 atcgcgtttc ccctggtaga aattatggaa tgatgccagt tcaacaaaat ttacattcga
    24301 taccggagat aaacgcggcc ttaaatgaaa aaccgccgga agttgggcaa aatatgccgc
    24361 tggcaatgac atggttgaca atgccggaat aatgcccagg tcagtaaagt ctgccgtaat
    24421 tttacttaca gattcgtcaa gctccctgat actgtccgcc attaccatta gcgtgaaatg
    24481 gtagtaacca aaggatatat caccggacac aatatcattt tttgcctttt ccagttcctg
    24541 caattgagta accgcatcat cttctgtact ctttaactgt ttttccgcac gtttaatggt
    24601 actcaatgct tctgatttgc tcatggatgt atatgaatgc gtaataatat agtcagcatc
    24661 agaatactgg agcacatcaa aaacaccgga tgcagtctca ctacagaaat ctttaatttc
    24721 aatagaacga aagaatttat ttccatcaat gcggcatatc tgtccggtat catgattaaa
    24781 aaatacatcc actccaccaa gaacgttata caccggagaa tcagtgactc tgattttttg
    24841 caacttccct gtcagaagat aattatagaa tgacagttga gaagaaaata cctttccgtt
    24901 ctcctcatac ataccaagaa gtttacaggt aaatttatca agagcgccag agaatgtatt
    24961 aatcatttca ttcattctct tcacatgaat gttaatatca tctttctttt ctttaatact
    25021 ttttttgcgt ttttccagtt tttctacacg cccatctggt ctgtagatca gcgtaaagta
    25081 aagagtgttc cccttgaatt tatttttctt catcgaacca tagtaacaat ctgatattat
    25141 atcagcatat ttattacctg attttgtggt aaaggcatca taaaaactcg ccctgcatga
    25201 atggttataa aatgaaacgg gcagtccgga aaatgaacga acaagagtgg caacctgtga
    25261 gtcaatagtt tctaacatct ccgcagagat tgactcaaag ttaatcccca tcagttgcca
    25321 tgtcgctaca taatcaccgt tctttgtttt gacaatattt ttatcaacat ggcttgaata
    25381 gggtatatat ttaccagtag tgattcgctc attcagtttc atggcattaa caaactcatc
    25441 aatttcaaca gcttcatatt gtccggagag gaacgctcgt gcgccaaaaa aacgattaca
    25501 cactgagttt ccgagcattt tcagcttaag aaagtaaagg ttaaaaatgt ggtcgtcctg
    25561 tttagtgatc attctgagaa caaaaaccgc gacaggaata gccagccaga tcagcttgct
    25621 gatataaacc cccgccagaa ataacgcccc tgcaaccaca gtaagaggga cgacaggaac
    25681 acccacatac atagcagggc gtgtcatcgc tttataaagt gtagacatac tatcgtcccc
    25741 gctttattag ttaaccatca ttgatgcaac ttcagccgca ctggcgataa caattgcccc
    25801 gatgatgata ggtgagcatt cacgaatcgt gcttccacca aacagaacct tgtagccgac
    25861 ccacagacag gcaatagtca ccgtgaccag tgaaaggcca ctaagccctg ttttaacctt
    25921 ttccagcagt gtttccgctt ttgaaaatcc atccgcaaag gccggtgatg caactgttgc
    25981 cccggcgact gccataacta ccttattttt acgctgcatt acagcagtga cagatgaact
    26041 gatacgatta catactgatt tcttaaatga cattttataa gtcctgttaa ttaataactt
    26101 ttgttggatg tgagttatca acaaaagcag atttcagaat ggtttcgggc cagataactg
    26161 acgcattgtg tgaacgattt tttcgctgtt ctcccccgtt gcttcttgta cctggtacaa
    26221 catatttttt ttcgttccct gtataaccaa ttcgctcaac ataacttgta ttattaaatt
    26281 ctttttcttt tcgcttaccg ttactaaaat ttcctgtata gtaacaacta agcgcattct
    26341 ccaggctcct ccctcgttta taacaatcca cgataatctt ttcgaaaaca gacaagtttt
    26401 cacacgaatc aaggagtttt tctgcggacg tggaataaaa agaaaaatta ctgctggtaa
    26461 tctgcatcaa tccgacagaa taacgtcttt ttctgttttc aatttctctg ataactgtta
    26521 gagcttcctc cttacttttg ggcatatgac tgataacact tttgccatag ctaccgcgtt
    26581 ccctttcagg aataatttca gccacagcat aaggattgaa gccactctcg acccgtgcaa
    26641 tatcatttat cgtatccgga tgaactgacg ccgcacacag caacaaggct gggaataaag
    26701 acgccatagc taacgctcca tatatccatc aatacgcata ctctgcatta ataagtaaat
    26761 aatttgcttc ctcttactaa gcaaagatgt tttcgttttc tcttcgataa atgcattcaa
    26821 cctgggatcg agttttatcg tgacataaac ccctttttcc gatgacttat ctgatttctc
    26881 cttcatttaa tcaatccact ataagtgtgt tttggatttg ttttagatgc gaacatgatt
    26941 cgcaaaataa caatgctcaa caatacgatc aaataacatt gacaaaatgg tcatattatg
    27001 attcgtgtga tcatgcaaaa aaaagcgccc atatgggcgc tctagtatga ttgaaacatt
    27061 agttaatcga atgtagggac tggagcatcc ttctgagact gaataaacaa tgcttgttta
    27121 acattcttac agttctgaga atcagagcca gacttctcac actctgcctg cttttgttta
    27181 gcttccgtaa gatgctgccc ccaccaatcc acacttttta cttcttcact acaaccaaca
    27241 acgaagaacg gcaaagcaaa aagcagatat tttttcataa attccccctc tcactgatcc
    27301 tggaaagact tgacacgaga agggcattag tccgaatgag taccagtgtt ctgatccctg
    27361 ccaacgagac acctcccagt tcagctctta cagaatcgag atattttctg acagttgaag
    27421 gctttagtcc tttgaaatca gcaatttcat tcagggtata gccataagcg tacatcagaa
    27481 taatgtcttt ttgttgctca ctcaaatgtt cttcatcact aaaaatttga tgaagtgcag
    27541 aaatgcagat agcatcatgc tcagtcatga taacctccct cgtaggttgt tgtgatcagc
    27601 aggtgagcaa agtagccgct ttgttcacct gcgccaaaat caaattaaaa tcccaggcct
    27661 ttccagttcc tctcttgctg tattcttagt tttttatgtt cttctgaatc ctttgtaaac
    27721 ccgtgttcaa gagcaaaccc gatattgtga ccttgctcat gttttctgga tagctgcttt
    27781 ttaacgtcgc tctcttccgg ctgcctggtt tcacgctcat gaacctgacg ttctctgttc
    27841 cgctcaaggg caatattttc aatctgccag ttattgcgat gcgtttccct gtagcctgca
    27901 acagttccat catcattaaa cattggacta cgtacaagcg taggagccag tttttttact
    27961 ttgataagcg ttcctggctg gagcttttca gactcgaaat gatttttcag gtctttaccc
    28021 caaatcgtaa cctgttttcc accttttaaa gtttcataag tgaggaaagg tgttcgtttt
    28081 tcccctgcct tattctgata tgaagtctcc ccaaaatcca ccaccttgta aacattccgg
    28141 agtcttttcg gattttcagc ctgtaatcgc tcaatctccc gtttacgttc gggatctttt
    28201 ttccaggtag cggtaacatc atatcccata cctttcagtt ttctatgaaa accgtttctg
    28261 aacttcctgg tttcagattt agtaagtctt aatcttcttc ctgtttcttc atcacgaagt
    28321 ttaatattaa catgtacatg aggatgatct tctttatcat catggtatac ggcaacgaaa
    28381 gcatggtttg gataagtctc tttaagaaat tctaccgtag ctttcagagc gtcttccctg
    28441 cttactccag cttctggtgg tggtgaaaag accatgtttt tcacatgatc gatgttttct
    28501 ccacgatatg tcctggagta atcatttcct ttagataaag ttgaagtaaa ctccctatta
    28561 aagtcttctc ctttccctgt ttgctctgaa ccttttccat cataacagta agcctcaagt
    28621 tcaccattac gggtaatgta atcaatacca tttttgatgc ctgcggctgt tttacctgag
    28681 ccagtgattt taaaagtgac ttcttttgta ggtgtccagg tatatgcttt cttgtccgca
    28741 ccatgtctga ctttatgatt aaaagccgat ttactggcat gtatatgtct tcccgataac
    28801 ttaggagatt tcggatcacg cccagtccct ttagcgcgtt taatacggta ttcctgttct
    28861 acatacacac ccataaatca cccaaatctg ttaacaacac tcttggttaa cgtttcaagt
    28921 tttgaatcaa tttgcttaca cagttcaatc acttcaataa cgtcttttct gaaatctgga
    28981 tcgttaaccg tacagaatct ttcacctttt atgataaaat gaatgttgcg accaacacga
    29041 tctacagcag ttgatagttt tttaagttcc ttaacttcat cagggtaaag acagacttca
    29101 ctctttaaca aagactgacg cacacgaata gcaatttctc tgctcatgct catgccgtga
    29161 agagcagcat tacgtttaac aagttctatt tcatgagggt aaagacgcac tgataccagc
    29221 tttgctggtt cattattaac tgggatgtta acaggcttgg tttcaatatt aagcacgtta
    29281 tgcttagcaa aagcattgat actggtaaat ccacttaaaa tagcgttatg ttctgcaaat
    29341 tttaactcat catcacttag cctgaacgct atcatcttca taagtcaccc caacagagcc
    29401 tgcggcaggc acaggcaaaa acatcgtttt tggacaatct gattcaaatg ttaacatttg
    29461 acatcggatt gtctatcctg cattgattgt accatatgtg gcactgtgcc tggctataaa
    29521 atcgtcgctg catatgtcca gatttcgttg ctgaaagatt ctttcgtctt cgaccatcag
    29581 gcaaacgtat agctgaaaga tttgtgaaag aaaaaacagg cctggcaggg ctgggaattg
    29641 ttacggctga agccgtaacg ctttttaagt cctcgctgcg ctgcggggct tccggcgcaa
    29701 agcgcctccc atgcccttac agggcataaa aacaagggca attaagcccc tgcgcgatga
    29761 ttgctgactt ctttttccag agccttatta acaaaggcat tcaacgataa atcttcttcc
    29821 atcgccattt ctgctacccg acgatgcagt tctggatcaa gcctgacgtt aaacacgcct
    29881 ttaaacgggg tatcaggttc ctttccatcc tccacacaag actgtaaata cagatcaaca
    29941 gatgttttaa actcctgttc cagttcagct aatgtagaag cctcataagt taccaggtcc
    30001 cgaataaacg ccagttttcc atacaggaca ttattttcaa aatcgggttc aaccgtgcct
    30061 aaatatcctt tatattttaa atgtttcata ataatccagc ctctttcaga ttctgtttaa
    30121 ttgctttcag cgtaccacct ttgatataac tttccggatg tggacgatgc attaatatgg
    30181 tgtgattgat ttcagcattg aaaaaccgca ctcttgaccc ctgcatttcc tttttgacat
    30241 atcccaaaga ggaaaacaaa acgaccagtt catcccattc aaacgttttt ttactgttta
    30301 aaaactttgc cagtagctta tctgttttcc ccataaatcc atcccctata gatatgcaac
    30361 taattatagt tacacatggc atttttgtca aaaaatacaa aggggcagaa agcccctttt
    30421 tttatttaaa acatttcata cccttgcaag tagtttaacc accaccggaa ttgatcccat
    30481 tcgctaaatt tcattgccgg aattctggtt tcccagcctt tgacaaggga atcagcaagc
    30541 tgtacgatct gccgcgttga catttaaaaa cctcattcag ttttgattgt cgataacgtg
    30601 atcaggttgg tggaacaacc tgatcacacc ttgaatagtc agtcattacc ctccttcttt
    30661 tctatagtta ctgtgtatcc gtaaagagtc aaaatgcgat aagcatccaa cgcctcacgc
    30721 tcacttttaa atgttctgac ttcgtgtaat cctttacctt tatcaaggga tacacaaaac
    30781 tcataatctt cttctacttc tatcttttta attaatttat caagttcggc taatgttcgt
    30841 tttggctcaa aaagaaatgt gcattgtaca atggcgttta aatcttcccg atcaagctct
    30901 aacagagcat cattataagc agctttaaaa cagcgattat tacgcagatc agatgcaaac
    30961 tgcattgcgg cttgttttaa cgttttcatg aatttccctt gcattgatgt taatagacaa
    31021 tttcagaatc aatattgaaa tttccagaaa atgcagggat gcccctgcat tcataatgct
    31081 taacaaagac actcaataaa atctttaaaa ctcaagcatt catcgccatc ttttaatgaa
    31141 tcaaaatatt tttcatattc gtccctgtag aaaaggacta aatcaacatc actctgctta
    31201 agttcgccaa actgaggaac aattccggct ttatagtcac gaattttatt gttatcagta
    31261 aatatgacaa catactgttg tccagtatcc ttatgcataa ggataatagt gcaaagcgtt
    31321 actcgttcga atgtgaaaac atgattagtg gttgaagtaa aaacagatga gcatttcatt
    31381 ttaaatctcc tgccctgctg ggctattgtg agaggggcca ttcccctttc gatgaaacaa
    31441 taatacgacc tttaagtcgt atttgcaagt tttctcccgt ttttttactc gataagtgat
    31501 tgttatcacg ttttttaatc cgcgtaagcg gatggaaggg gcgaacgaaa ataccagggc
    31561 agcacaggag ccacatcgcc ccgaagcgcg gcgcagccgc tgacgaacgt accagggtgc
    31621 acaggccatc ccttcaccct gcaaagccca actgaccagc aggccatgat tatgctgatt
    31681 tgcgccgcag aatgccgcag ttagcgcgag cgcaagcgag tttaccccgc cctggtgcat
    31741 tgcagcatgg cggggcgctg tactgcgcgt gtgagcgtca gcgagctacg agcgcaactc
    31801 caggtactaa tataaaacca tcacaggtca ttttattttg actccctttt gcagagcacg
    31861 tattcaggat gttctcctgc aagtaacaaa agaaactcaa actcaaccag tgacagactt
    31921 tgactgtttt gagtattaac ttcctctttt ttctgccagg ttcttagccc aacaccataa
    31981 atatgactgc attccttttg tgttaatcct gcttttaaac gtaatttttt tacattttca
    32041 ggtgtattat cgggtttcat ttaacataaa ctccttaatt aaattcttaa ctggcgtctc
    32101 atcgtcttcc cttaatccgg cacacgtaaa atcaatatgt tgtaattcat tctcattcag
    32161 tacagcatca tacaatgtaa ttttcgtagt tttgttcccg attttaacat ttgttctggc
    32221 ttttatcctt tttgtaagcc tgtaattgtc accttctttt tcaagaaaat aagtcacatc
    32281 acctttattt tttctcataa ctgtttcaaa taccctgtaa ttttaacaag ttgatctata
    32341 ctcaagcccc gaatctgtaa atcataactg tcgccctgtt cggtgacttt accgttcaat
    32401 ccgttttcag ctttaaagcc tgtcaatgcc ccataccagc tttcaagctg gacaagttgc
    32461 gataacatac ctttcaggat cagaatttcg tccttttttt ccacctggtg tttctcatac
    32521 tcaatcgcct gtaacacctc ctgcgaagca tttaccagaa tttttcgctc gatatcggct
    32581 gcaatatcaa cgggattccg ttttctggat aacgtgcaaa catgatgcgg actacgccag
    32641 gaacgactat ccacactccc caccacagaa aagcggtctt tttccatccg aatatgcaca
    32701 gagtaatttt taaactgcgg tgacgtcagt tttatacgag acgaacaatc atcaagtttg
    32761 ttcacgcgcc agccgttccc caggatacgg cagacaactt caaagacagg gtgatattgt
    32821 tcaaaaaaag agttcatctg tttccctttt tgctacgtgg ctgctgttcc cgtctttttg
    32881 ggttcgatgc cccaaaagac gggctggcta taatatcggg ggcttctcgc ccccgttctg
    32941 gttacgctct ggtttccacg cgttgccacc ctgtcgccct gcgctgtccg gttgtaccgt
    33001 attttgcgcg gatttcttct atcgtgtgtt cttcacgatt ccagtaactt ttatgttcgt
    33061 ctggacgata aaaccattgt tttttctttg ccgcccattt acacccgatt tcttttaaag
    33121 tttccttatg tgtaatggtt tctccactaa tccagaccca gttacctatc acttcaaata
    33181 ccagaccaga taaaccagaa agaacgttta atactttttc caggtcatca ccgtaattat
    33241 atcgtgcatg ttcatcagtg ctctggaact gatttatttt atcaatattt gccatcaata
    33301 catcaaaagc tgcatttacc gctttcatca gttcagcccc taacgggtta cgatctggat
    33361 gatattttaa agcggctttt ctgtatgctg ctttgatatc tttttcagtt aattcgccgg
    33421 ataatccaaa aacgtttaat gcttcctgga tattcatttt tttaatctcc tgccctgctg
    33481 ggctattgtg agaggggcca ttcccctttc gatgaaacaa taatacgacc tttaagtcgt
    33541 atttgcaagt tttctcccgt ttttttactc gataagtgat tgttatcacg ttttttaatc
    33601 cgcgtaagcg gatggaaggg gcgaacgaaa ataccagggc agcacaggag ccacatcgcc
    33661 ccgaagcgcg gcgcagccgc tgacgaacgt accagggtgc acaggccatc ccttcaccct
    33721 gcaaagccca actgaccagc aggccatgat tatgctgatt tgcgccgcag aatgccgcag
    33781 ttagcgcgag cgcaagcgag tttaccccgc cctggtgcat tgcagcatgg cggggcgctg
    33841 tactgcgcgt gtgagcgt
//
