LOCUS       NZ_CP063984            24185 bp    DNA     circular CON 16-JUN-2023
DEFINITION  Escherichia coli strain 25DN plasmid p25DN-A, complete sequence.
ACCESSION   NZ_CP063984
VERSION     NZ_CP063984.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN16622485
            Assembly: GCF_015290725.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24185)
  AUTHORS   Cao,G.
  TITLE     Complete genome of 25DN
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 24185)
  AUTHORS   Cao,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2020) Shandong Medicinal Biotechnology Center,
            Shandong First Medical University, 6699 Qingdao Road, Jinan 250117,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 10-2020
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 420.0x
            Sequencing Technology             :: BGI
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 06/16/2023 15:09:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,987
            CDSs (total)                      :: 4,872
            Genes (coding)                    :: 4,562
            CDSs (with protein)               :: 4,562
            Genes (RNA)                       :: 115
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 6
            Pseudo Genes (total)              :: 310
            CDSs (without protein)            :: 310
            Pseudo Genes (ambiguous residues) :: 0 of 310
            Pseudo Genes (frameshifted)       :: 171 of 310
            Pseudo Genes (incomplete)         :: 133 of 310
            Pseudo Genes (internal stop)      :: 68 of 310
            Pseudo Genes (multiple problems)  :: 54 of 310
            Pseudo Genes (short protein)      :: 4 of 310
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP063984.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..24185
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="25DN"
                     /isolation_source="LAB"
                     /db_xref="taxon:562"
                     /plasmid="p25DN-A"
                     /geo_loc_name="China:Jinan"
                     /collection_date="2017-05"
     gene            complement(join(23848..24185,1..70))
                     /locus_tag="IR210_RS24495"
                     /old_locus_tag="IR210_24500"
     CDS             complement(join(23848..24185,1..70))
                     /locus_tag="IR210_RS24495"
                     /old_locus_tag="IR210_24500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001546356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001546356.1"
                     /translation="MSLTLPLMYFQTGADLSKITHHEVHYQDGFVQQAWLQPEIQLFVV
                     CIARKKGSRREIKGGMAVLTSIPASNGAELAKALDNVMRQSDELRPLAGKDENVFIPAR
                     IGISGEEPPTEQELLSVFYQQCLKHGSWGSA"
                     /name="hypothetical protein"
     gene            complement(125..>478)
                     /locus_tag="IR210_RS24500"
                     /old_locus_tag="IR210_24505"
                     /pseudo=""
     CDS             complement(125..>478)
                     /locus_tag="IR210_RS24500"
                     /old_locus_tag="IR210_24505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015059103.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS family nucleoid-associated regulatory
                     protein"
                     /name="H-NS family nucleoid-associated regulatory protein"
     gene            complement(709..981)
                     /locus_tag="IR210_RS24505"
                     /old_locus_tag="IR210_24510"
     CDS             complement(709..981)
                     /locus_tag="IR210_RS24505"
                     /old_locus_tag="IR210_24510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001547192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000160399.1"
                     /translation="MTKHDFVSFVSGELRQGAVRFSLAFNSKGEIVLHWTNKAGIRVWR
                     ILSGNRGKKPSKANLERMSNFRRWLFDARQGMEGYTQQPEQSNLS"
                     /name="hypothetical protein"
     gene            complement(994..1143)
                     /locus_tag="IR210_RS24510"
                     /old_locus_tag="IR210_24515"
     CDS             complement(994..1143)
                     /locus_tag="IR210_RS24510"
                     /old_locus_tag="IR210_24515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000003880.1"
                     /translation="MSERILSAINDVEKGGRPVFPLMPFHVFPEYMALLRKALEKKTQK
                     RTDK"
                     /name="hypothetical protein"
     gene            complement(1229..1408)
                     /locus_tag="IR210_RS24515"
                     /old_locus_tag="IR210_24520"
     CDS             complement(1229..1408)
                     /locus_tag="IR210_RS24515"
                     /old_locus_tag="IR210_24520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_071526261.1"
                     /translation="MEREFSAKASLNRNIKFWFEQCGLSKERVIHCIDNWYDLAYPPSE
                     QEKVRTGESKKRSN"
                     /name="hypothetical protein"
     gene            complement(1451..1780)
                     /locus_tag="IR210_RS24520"
                     /old_locus_tag="IR210_24525"
     CDS             complement(1451..1780)
                     /locus_tag="IR210_RS24520"
                     /old_locus_tag="IR210_24525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000866648.1"
                     /translation="MKVLTFKNDTVSVGDIFVSSWGYEQTNVTFYQVLSVHGKKTVTVR
                     EIRANSEYTDSMVGFKTPVLNDFTGECFKRQIKDFGDELAIKIEDFETAYKTLPEEKHR
                     FSSYY"
                     /name="hypothetical protein"
     gene            complement(1873..2088)
                     /locus_tag="IR210_RS24525"
                     /old_locus_tag="IR210_24530"
     CDS             complement(1873..2088)
                     /locus_tag="IR210_RS24525"
                     /old_locus_tag="IR210_24530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001180116.1"
                     /translation="MQNKPTPEEVKNARVAAGLTLKEAADIFGYQLNSWQMKESAGKAS
                     RSLSIGEYQYLLLLANMHPSYRLVKK"
                     /name="hypothetical protein"
     gene            complement(2078..2323)
                     /locus_tag="IR210_RS24530"
                     /old_locus_tag="IR210_24535"
     CDS             complement(2078..2323)
                     /locus_tag="IR210_RS24530"
                     /old_locus_tag="IR210_24535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001550454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000356548.1"
                     /translation="MDKDKIIKKNRGNYSYVIRTMDEDGDTVFHVLKYVKTIDKTKSRK
                     TVRKLIMDEKLNLASLMLLDNWVLCDCLTKGDENAE"
                     /name="hypothetical protein"
     gene            complement(2368..2691)
                     /locus_tag="IR210_RS24535"
                     /old_locus_tag="IR210_24540"
     CDS             complement(2368..2691)
                     /locus_tag="IR210_RS24535"
                     /old_locus_tag="IR210_24540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001181903.1"
                     /translation="MQNYAKSVATEILRQLGGNRFIVMTGAKSFSYFDENGECGLTFRL
                     PSNFAMKGINLVKIKLDFTDTYQVKFSRVRGAEVKDISRFDNIYCDQLARLFTQETGLH
                     TVL"
                     /name="hypothetical protein"
     gene            complement(2837..3118)
                     /locus_tag="IR210_RS24540"
                     /old_locus_tag="IR210_24545"
     CDS             complement(2837..3118)
                     /locus_tag="IR210_RS24540"
                     /old_locus_tag="IR210_24545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001694627.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_000220560.1"
                     /translation="MTYELAFDRRALKEWQKLGHTIREQFKKKLAERLENPRVPAARLH
                     GHADRYKIKLRASGYRLVYQVIDEKVVLLVIAVGRRESSEVYQIADLR"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(3108..3359)
                     /locus_tag="IR210_RS24545"
                     /old_locus_tag="IR210_24550"
     CDS             complement(3108..3359)
                     /locus_tag="IR210_RS24545"
                     /old_locus_tag="IR210_24550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000121741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="WP_000121743.1"
                     /translation="MSYQILTTTAASITDLKKNPMGTVAEGEGDAVAILNRNEPAFYCV
                     PPKLYAYYRELAEDAELNAVADERMKNPEIVKVNLDDL"
                     /name="plasmid stabilization protein"
     gene            4581..5420
                     /locus_tag="IR210_RS24550"
                     /old_locus_tag="IR210_24555"
     CDS             4581..5420
                     /locus_tag="IR210_RS24550"
                     /old_locus_tag="IR210_24555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001722379.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_001546350.1"
                     /translation="MNLLSVTKKTKIRHRNEINSTFSSLPLSARRILFMAMAQIDSREE
                     LSEGATFRITAREYAFIADIDVTGAYRQLKEGAEELQASVIRIPRNQLLTAQGNQSSGH
                     TKKRGKLPSDAVRLMNLTAFCDYVESEGYIDIAFSHVIEPYITMLKDSYTTQVLISSVR
                     LADQNSNMLYQFIRKQYSSGKKTFFDIEVDVLKDELELFRIDNGEKVYLYQNFKDFNKV
                     FLQKNIEKINQYTEINHLEVKIIERVARRASKLRFSYKIDKESEGLDTRIPYGFRGA"
                     /name="replication initiation protein"
     gene            5441..6283
                     /locus_tag="IR210_RS24555"
                     /old_locus_tag="IR210_24560"
     CDS             5441..6283
                     /locus_tag="IR210_RS24555"
                     /old_locus_tag="IR210_24560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435061.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_194446392.1"
                     /translation="MEQIKLHKQGGAAVIIIPASMIENTGWEDGTLLDVLEINEALHIR
                     RKTGSGALATKSCPSLFSSTMRHVNYDKIIRYNSGLNLLVNELSFSARRFFFICLYYYF
                     ENKLESDKSLLIRADKYAEFVGVDRSVAYKQMKDAADFFSRNKKLITHCDYISNEGLLR
                     VMFSSKTINYITAIDARKYQVTELPLKSALSLQGRYSWPLYQLIKFSHLKSFTIGVDEL
                     KKEIGYIQNQKFSFFKRDGINIAIDEITERTDVKNIKCVNAERQGRRVSKVRFEIEMR"
                     /name="replication initiation protein"
     gene            6287..6730
                     /locus_tag="IR210_RS24560"
                     /old_locus_tag="IR210_24565"
     CDS             6287..6730
                     /locus_tag="IR210_RS24560"
                     /old_locus_tag="IR210_24565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001074379.1"
                     /translation="MAKIYQFPQGDERGKFREEIARERKKRFAVKTGSTFVKWLGWTWF
                     YLRLLVASVLHFISVFVLAILGAFKWAVFWLGGILCVITWYHLDHQLWTPQNLTIPVIT
                     ATWIFGLLAEPLMELLNKTMPWHKLLVPEPAGESTENSSETSQ"
                     /name="hypothetical protein"
     gene            6870..7226
                     /gene="ddp1"
                     /locus_tag="IR210_RS24565"
                     /old_locus_tag="IR210_24570"
     CDS             6870..7226
                     /gene="ddp1"
                     /locus_tag="IR210_RS24565"
                     /old_locus_tag="IR210_24570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA distortion polypeptide 3"
                     /protein_id="WP_001546351.1"
                     /translation="MKYQVREFITDKYAKAVNILKDNLKENYHVFYGVRLSEILFPASE
                     YGTDAFFKEFELINSVILPLVIFDLTQRKPMMIISFDKIPDASLLEGTNIVVLECTTLA
                     DLLTNDNIGFLYKS"
                     /name="ddp1"
     gene            complement(7223..8200)
                     /locus_tag="IR210_RS24570"
                     /old_locus_tag="IR210_24575"
     CDS             complement(7223..8200)
                     /locus_tag="IR210_RS24570"
                     /old_locus_tag="IR210_24575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6685 family protein"
                     /protein_id="WP_001269914.1"
                     /translation="MRYLTELICQLYRLTDHHKLTAATFKNLADIKLVEPTADADTILQ
                     LENIFSEYSLRYIDRDLAEILSNIITTDKNHSLDFDFNKIQSLTASKSFGCGWNKVING
                     SWFKNLYSWGEGMYPAKNLKAENISDWEDNIWHIEHEGFNPRDPINVKYYSWLDRYVAL
                     NSGGSHHAAMVVYQSVRDKLEYKREAVIEQLSINSNTVEILGQNYYSFIFQIKHPSNKT
                     ENYTSEYEFTDALKDFGQNRHTTLKPVNYVSNIKLAFIPKDALKTNSETFRNWFYSAIS
                     YGKIISLPDYLKNPAHYHTYHYSHELDSITLGNPSRKYKLRGDS"
                     /name="DUF6685 family protein"
     gene            complement(8225..8506)
                     /locus_tag="IR210_RS24575"
                     /old_locus_tag="IR210_24580"
     CDS             complement(8225..8506)
                     /locus_tag="IR210_RS24575"
                     /old_locus_tag="IR210_24580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001185482.1"
                     /translation="MALKLNRPNIDESQQPATNAETARFISGATRAPVVGKPKLMNFRL
                     SAHFEDILEAEAIRTGQSKTTVLKAALAMYNSQDENIKNHWLLESAKF"
                     /name="hypothetical protein"
     gene            complement(8604..9266)
                     /locus_tag="IR210_RS24580"
                     /old_locus_tag="IR210_24585"
     CDS             complement(8604..9266)
                     /locus_tag="IR210_RS24580"
                     /old_locus_tag="IR210_24585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division plane positioning ATPase MipZ"
                     /protein_id="WP_000516402.1"
                     /translation="MGKILLVVSDKGGVGKSTYVANTGSMLVNKGKSVIILKTDKNHDL
                     LSWNEKRTDNGLLTIPVHAAYGNVSNEIKRLSKLCEVLIVDCPGHDSQEFRSALTVSDI
                     VVTLVKPSSDFESETLTSVTEKIRTAQKANAALEPWVLFTRINSAKPRHRKAAIDLDKL
                     LRSDNIWIQPLKTRISELDVYESACNEGAGVHDVSRASSLSTAKAQIELVAQEIGIL"
                     /name="division plane positioning ATPase MipZ"
     gene            9647..10291
                     /locus_tag="IR210_RS24585"
                     /old_locus_tag="IR210_24590"
     CDS             9647..10291
                     /locus_tag="IR210_RS24585"
                     /old_locus_tag="IR210_24590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001503708.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000203201.1"
                     /translation="MTSNAPTNFVRAYLRASTAEQDASRALETIEAFARERGLIICSYY
                     IENESGSRLDRPELFRLLRDCQQNDILLIEDVDRLSRLSGEDWNTLKKMIRQKDIRVMA
                     VNVPTTWINSGMSEFDSRLFAAINDMLLDMLAAVARRDYEQRRERQKQGIEKARKDGKY
                     KGRKPNQARHDAIIRLIESGSSWTQVQKVLGCSRGTISSALKRKTGQKSSK"
                     /name="recombinase family protein"
     gene            11113..11595
                     /locus_tag="IR210_RS24590"
                     /old_locus_tag="IR210_24595"
     CDS             11113..11595
                     /locus_tag="IR210_RS24590"
                     /old_locus_tag="IR210_24595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001546353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_194446393.1"
                     /translation="MRDKTREAMRMFLGGRCYTAENLERDFLSELTRYSDERWEAPQRG
                     ARLAAAVKRYKTSEMLRFIFATIAYDPDPDLTPLAVKRLCNALFGRTGSQWLIVELFGD
                     KERQHRSNDSTLEAVEKMAARYRHAARQHWAATLDEIERVKRLYQEGIKASRKKES"
                     /name="hypothetical protein"
     gene            11933..12544
                     /locus_tag="IR210_RS24595"
                     /old_locus_tag="IR210_24600"
     CDS             11933..12544
                     /locus_tag="IR210_RS24595"
                     /old_locus_tag="IR210_24600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000016733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000016733.1"
                     /translation="MSGRITTLCTAFGVVIAAVGLYLPYKNELNAALYQREFLTGKWST
                     DAEYIINSGDLGLDKPQSIMTIQLFVDKDGSIDGEFISEGLCDAMPLTWNITFNSDSPS
                     LINFIFARKFQIRQLVNGAMDKSPVVATLKLVDEDHKHNPIVFDVVNDSTGTLPKQITL
                     AKNLPKFEENYKYLQSYCANSTEKMYEKMMPEIRNLNKGL"
                     /name="hypothetical protein"
     gene            12636..13145
                     /locus_tag="IR210_RS24600"
                     /old_locus_tag="IR210_24605"
     CDS             12636..13145
                     /locus_tag="IR210_RS24600"
                     /old_locus_tag="IR210_24605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000190058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000190051.1"
                     /translation="MATEWVDVADNAVKIGLGALITIVGGWITLKLTHCHEIRKDAIAQ
                     RLRDIDKKTDRYIDFLSSSQTLMQKYLYESCNPGSEDYTNYMRLHNIVSLTSSPELRIY
                     AFDTQSKVSQFILLRKPNEPEVIDSCRNAARNAVSVLQGAVSAELLQDKAALQDKQHAW
                     WAFWRK"
                     /name="hypothetical protein"
     gene            13251..15152
                     /locus_tag="IR210_RS24605"
                     /old_locus_tag="IR210_24610"
     CDS             13251..15152
                     /locus_tag="IR210_RS24605"
                     /old_locus_tag="IR210_24610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000407093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_194446389.1"
                     /translation="MEIVSFKVSQYRSISGEISSDNFNGLTIVGQNNSGKTNLLKAMRV
                     FFEGKFNPDLYDYEKDKPHGVKQGQTSFAVRFTFSESELDDVSEDLSQDDDDDDDDSII
                     ELGVLGGQEEPSNSISFDDGSSKQQESKPTQSRGRKLSLRDRYLQLFNMIDDSRLSSPQ
                     NEVTVHLTISNKNNYFYTVFKGYKRKPEVTSSMYTSVERRFIEKILSSFECVYIPSSKS
                     IDDIYHNLLVPYVRSEVASAMKTSVQVIHDKLLEVSEKITNEMILSGIDDCSFMIKAPP
                     SLDELFGRFEVSIKDTIENVISSKGMGLQCLSLFSSFKSISERKLTLGKKTIWMVEEPE
                     SFLHPSLGRSCNHIFKSLMDVAYVLITTHSLSFVSDEPSKIIELYKDDAGVTKDKKHEK
                     RFNAVASIRENLGVRFSDFFNISSSAVFVEGITDKQYIESILKLTSEHDELKNRWPFLR
                     SAKVDEFGGVSQLGGFLKGCYEFISKDVPVISVFDGDEAGVKERTRLQSYFGKKQIRFE
                     SNKDYISVRSGFAIEGLFPDDFISDAMETHPSWFIGGKSVDADDVIEPFKVQDNKKTNL
                     LNFFLERCRVQPICGWISRWEKVFNVIDSALRDKSESITNKKRTEDTSGNTSDHQAA"
                     /name="AAA family ATPase"
     gene            complement(15557..15736)
                     /locus_tag="IR210_RS24610"
                     /old_locus_tag="IR210_24615"
     CDS             complement(15557..15736)
                     /locus_tag="IR210_RS24610"
                     /old_locus_tag="IR210_24615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000347020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_194446390.1"
                     /translation="MDFMSILGRCLLLPFPVAMFVGCLFLGIDDRFTGMFMSFIVGCLS
                     WYITKPKTQKAEVA"
                     /name="hypothetical protein"
     gene            complement(15803..15898)
                     /gene="dqlB"
                     /locus_tag="IR210_RS25270"
     CDS             complement(15803..15898)
                     /gene="dqlB"
                     /locus_tag="IR210_RS25270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinQ-like type I toxin DqlB"
                     /protein_id="WP_000609147.1"
                     /translation="MINLLIIVLRAVVAVANALIAILELIRQFID"
                     /name="dqlB"
     gene            16663..17697
                     /locus_tag="IR210_RS24615"
                     /old_locus_tag="IR210_24620"
     CDS             16663..17697
                     /locus_tag="IR210_RS24615"
                     /old_locus_tag="IR210_24620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="WP_000973426.1"
                     /translation="MMIQSHPLLAAPLAVGDTIGFFSSSAPATVTAKNRFFRGVEFLQR
                     KGFKLVSGKLTGKTDFYRSGTIKERAQEFNELVYNPDITCIMSTIGGDNSNSLLPFLDY
                     DAIIANPKIIIGYSDTTALLAGIYAKTGLITFYGPALIPSFGEHPPLVDITYESFIKIL
                     TRKQSGIYTYTLPEKWSDESINWNENKILRPKKLYKNNCAFYGSGKVEGRVIGGNLNTL
                     TGIWGSEWMPEILNGDILFIEDSRKSIATIERLFSMLKLNRVFDKVSAIILGKHELFDC
                     AGSKRRPYEVLTEVLDGKQIPVLDGFDCSHTHPMLTLPLGVKLAIDFDNKNISITEQYL
                     STEK"
                     /name="S66 peptidase family protein"
     gene            complement(17754..19523)
                     /locus_tag="IR210_RS24620"
                     /old_locus_tag="IR210_24625"
     CDS             complement(17754..19523)
                     /locus_tag="IR210_RS24620"
                     /old_locus_tag="IR210_24625"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231998.1"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_000057520.1"
                     /translation="MAQKITPSKIVKHARELIIKGIESGENSFVIFDVDGALERLDHYR
                     CQLKSFFPNSSIAYSYKSNNLAQWCQIISGKGLYAEVCSVDEMNLAKRDGFKRIVFDGP
                     LKKTSELLKAIEIGALIEVDNIDECKRLNELCKLHKLTCRIHLRLSHYYDDNLSRFGLS
                     ESEAINLLEMLISKSEYLILDGFHLHVGSNLPNAEKICKAIIQYHELILRYMPDDGTLN
                     LGSGIPADSFSASSDNPTPCPEVFFSSIYDTIKNCFGTVCDKWNYIFEPGRHLVEDFGY
                     FIGKVISTKNRYGVKVAQTNIGINWIPSIRNWDHSFTLFHNHNHISDDKSDEYIIAGFN
                     CFECDCLFPSVILPSNLSDYLFSVRGCGAYDMQTGNQWTRNLYAVYTITNDVVNISRIH
                     RRELDFRKYDVSLTPSGIKVNDEITLLYPALKYAEELYLLINQNKINFIKSMAWPAFVN
                     NISDSVSFIEQSMIDNQNEKALILFIKYKTKIAGVVSFNIIDHANKTAYIGYWLGANFQ
                     GKGIVTNAINKLIQEYGDSGVIKRFVIKCIVDNKKSNATALRCGFTLEGVLQKAEILNG
                     VSYDQNIYSKVIG"
                     /name="GNAT family N-acetyltransferase"
     gene            complement(19508..20311)
                     /locus_tag="IR210_RS24625"
                     /old_locus_tag="IR210_24630"
     CDS             complement(19508..20311)
                     /locus_tag="IR210_RS24625"
                     /old_locus_tag="IR210_24630"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152798.1"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]; GO:1904047 - S-adenosyl-L-methionine
                     binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_000152799.1"
                     /translation="MTIKHAEELTEEVILNMNYPDFVALMQQDNTPPGAEYTIDYWIKH
                     GCINKKSHLLDLACSTGFSSRECFKKEGASAEGIDISESAVMVANEKAKKLKANNLLKY
                     YVADACDLPFEDNSFTHVLGGCNFAFIQNRLIALNETHRCLNHMGSMCISNFYYRRKIS
                     DKLINDVYNAINFRPNPLWTLEYWHQFFSERFTLVSEENHEMESQSEDELKADIYDYIF
                     NRNEFTKGLNGSLQNVFFERFLKIRRPLNIQRDYQGVTLQIWRKK"
                     /name="class I SAM-dependent methyltransferase"
     gene            complement(20308..21522)
                     /locus_tag="IR210_RS24630"
                     /old_locus_tag="IR210_24635"
     CDS             complement(20308..21522)
                     /locus_tag="IR210_RS24630"
                     /old_locus_tag="IR210_24635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001090465.1"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="WP_194446391.1"
                     /translation="MNTANILSVNYGAYNAIRMLIGVYHAAFLISTGVTISQLAVLQIV
                     FSVTVLILDFPLSVIADRFYRKQVVVSGVFFTILFYPLCIQSPDMLALVFSEIFYAIGI
                     CCISGAIEGWVLSALDGRNEKFTLCAHLCERVSSFGGVITGAVGILVVYFYDSYKSGYI
                     VSFFLMFVVFIVFLCVKTNGSGGEKEARDSIIKQAKESIGLITGSYNGTYFLSITCMFT
                     IGIQVIYHFWQPIMLSGESIGSLSKRELITLLMCHIGAFSMQYIANYLMPKIDVRCKLY
                     ILVCTLCSFLSSIACILLFMLITDNKVVLGVAIFSIIHGMISTIPVGAQNIFISRLNGN
                     YKNIISGALGLVSLSCRVASISVLGVISVLPGNMPVTTYIFISAIACVLCGCLFLMWSF
                     KKEMV"
                     /name="MFS transporter"
     gene            complement(21519..22646)
                     /locus_tag="IR210_RS24635"
                     /old_locus_tag="IR210_24640"
     CDS             complement(21519..22646)
                     /locus_tag="IR210_RS24635"
                     /old_locus_tag="IR210_24640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="WP_000417394.1"
                     /translation="MEKYKCPLNATLYRVAYKSYLRGLFMDYILGRYVKIARYGSGGLV
                     GGGGKEQYVENLALWENIIKTAYCFITPSSYTAALETANIPEKDFSNCFRFLKENFFII
                     PGEYNNSTENNRYSRNFLHYQSYGANPVLVQDKLKNAKVVILGCGGIGNHVSVILATSG
                     IGEIILIDNDQIENTNLTRQVLFSEDDVGKNKTEVIKRELLKRNSEISVSEIALNINDY
                     TDLHKVPEADIWVVSADHPFNLINWVNKYCVRANQPYINAGYVNDIAVFGPLYVPGKTG
                     CYECQKVVADLYGSEKENIDHKIKLINSRFKPATFAPVNNVAAALCAADVIKFIGKYSE
                     PLSLNKRIGIWSDEIKIHSQNMGRSPVCSVCGNRM"
                     /name="ThiF family adenylyltransferase"
     gene            complement(23127..23591)
                     /locus_tag="IR210_RS24640"
                     /old_locus_tag="IR210_24645"
     CDS             complement(23127..23591)
                     /locus_tag="IR210_RS24640"
                     /old_locus_tag="IR210_24645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001443073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001443073.1"
                     /translation="MNMTARNAGLSFRSPDDDDSHRTRYSELQQAFDFYNQRLFDGELP
                     ECLITFQRVTQDLFQGKFALSWFDRFSVQVEQQKEMAAVIEQWRETIAQAHQNAEPGLI
                     LKRCCQCHRRTGAMITICLLRLLRTSQKGTKSNISVGVWCCCLGEVRTEY"
                     /name="hypothetical protein"
     BGC             11519..24185
                     /name="RRE-containing"
                     /gene="RRE-containing"
                     /tool="antismash"
     Typing          6288..6733
                     /name="IncX1"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="94.855"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 cttcatgatg tgtgattttg ctgagatctg cacctgtctg gaaatacatt aatggtaatg
       61 tcagactcaa aacatcctcc tgtttatcaa aaaagtctcc tgcgtaaacc agaggcttat
      121 tatattaatg ttcgtcgcca gcagagctgg aagcatcttt tttgatgata aactcatcaa
      181 gagagcgacc gcctgccagt gcttcagcaa tcggttttgg tgcacgccca cgaccagacc
      241 agtatttcgt ttcaccattt tcttcaaatt gatacttggg cggcgctttt ggtaacgttt
      301 ttttacgtgt ttttggcgca tcttcggtaa tgccaagcag ttcttccggt gagaaaccct
      361 ctccggcgat taactgaagc agttcctgac gtttccgttc acgctctgct cgttcagccg
      421 cttcacgttc agcatcttca cgacgttctt caataacaac gttgagcttt tcctgcatcg
      481 ccgtgaatct ggcgccgctc ataaatagtg cttgagcatc aacaaaaatg caaaaaggct
      541 gatgttgtca tggctgaaca tacgtacgtc tgcgaccgga aacccgatca atgcggtaag
      601 gacagtgccg tcaggttcgc tacgcgaacg gtctggcagg aagcgcaagc gcagtcccgc
      661 gcaatatatc agaaagcacc tcccgaaata cgggagggct tcggctattc agctaaggtt
      721 gctctgttca ggttgctgag tgtagccttc catgccctga cgggcatcaa aaagccagcg
      781 ccggaagtta ctcattcttt caaggttagc tttgcttggt tttttgccac gattaccact
      841 taatatccgc cagactcgta ttcctgcttt attagtccag tgcagaacaa tttctccttt
      901 gctgttaaaa gcaagagaaa agcgtacagc gccttgccgc aattctccac tgacaaagga
      961 cacaaaatca tgttttgtca taaagcctcc ggtttattta tctgttctct tttgtgtctt
     1021 tttttccagt gcttttctga gtaatgccat atactcagga aagacatgga atggcatcaa
     1081 agggaaaacc ggacgcccac ccttttcaac gtcatttatt gctgataata tgcgttccga
     1141 cattttattc ctcgcaatag aatcaggtgt cacggtatca ggttgcccca caacctgata
     1201 ccatctttat ctttacttta ttaacttctc aattgcttct ttttttgctt tctcctgttc
     1261 taactttctc ctgttctgat ggtgggtatg caaggtcata ccagttatca atacaatgaa
     1321 taactctttc tttagataat ccacattgct caaaccaaaa ttttatattt cggtttaatg
     1381 atgcttttgc gctaaactct ctttccattt tcagaccttt actaaaaggg ggaatatccc
     1441 ccctgattaa ttagtagtaa gaagaaaatc gatgtttttc ttccggtaga gttttatacg
     1501 cagtttcaaa atcttcgatt ttgattgcca gctcatcacc aaaatctttt atctgacgct
     1561 taaaacattc accagtaaaa tcatttaaaa cgggagtttt aaagccgacc attgaatcgg
     1621 tatattctga attggcgcga atctcgcgaa cggtgacggt ttttttaccg tgaacagaaa
     1681 gaacctggta gaaggttaca ttggtttgct catagcccca tgatgataca aagatatcac
     1741 caacagagac agtatcattt ttaaaagtta atactttcat ttttagctcc cgcccagctt
     1801 gggctctgga tgaaagagaa cctgtttccc tttcctgtgt tttattatac ctgcatttgc
     1861 aggtatggca agttattttt ttaccagcct gtaagacgga tgcatatttg ctaataacaa
     1921 taaatactga tattcaccaa tagataaaga acgactggcc ttacctgcac tttctttcat
     1981 ctgccaggaa ttcagttgat aaccaaaaat atcagcagct tctttaagag taagacctgc
     2041 cgcaacccgc gcattcttta cttcttcagg tgtaggttta ttctgcattt tcatcccctt
     2101 ttgtcagaca atcacacaaa acccaattat ccagaagcat caatgatgcc aggttgagtt
     2161 tttcgtccat tatcaatttt cttactgttt tcctgctttt agttttatca atcgtcttaa
     2221 catattttaa gacgtgaaaa accgtatccc catcttcatc catcgttctg attacatagg
     2281 agtaattacc tctgtttttc ttaattatct tatctttatc catattattc ctcataacaa
     2341 aaaaaggggc ttaatgcccc tttttatcta taacacggta tgtaaccctg tttcctgtgt
     2401 aaataaacgc gctaactgat cacaatagat attatcgaat cttgaaatat ctttaacttc
     2461 agcaccacgt acacgagaaa atttcacctg gtacgtatca gtaaaatcca gtttaatttt
     2521 tactaagttg atgcctttca ttgcaaaatt tgacggcaaa cggaaagtta acccacactc
     2581 accgttttca tcaaagtaag aaaaactttt agcaccagtc ataacaataa aacgattacc
     2641 accaagttga cgtaaaatct ctgtggctac agatttagcg tagttttgca tttttaacct
     2701 cccgcccact ttgggctctg gatgaaagag aacctgtttc cctttcttgt gttttattat
     2761 acctgcattt gcaggtattg caaattttta atgctctcgc tctgactgta aacagtcaat
     2821 catttgatga ttaatcttag cgcaaatctg cgatctgata gacttcgctg ctttcccttc
     2881 ttccaacggc aataacgagt aaaacgactt tctcatcaat gacttgatat acaagtctgt
     2941 agccagatgc acgaagttta attttatagc gatcagcatg accatgtaac cgggctgcgg
     3001 gtacgcgtgg attttccagc cgttctgcca gtttcttttt gaattgttca cggatggtgt
     3061 ggccgagttt ctgccattcc ttcagtgctc tacggtcaaa agccagttca taggtcatcc
     3121 aggttaacct tcacaatttc cgggtttttc atgcgctcat cagcaacagc gtttaactca
     3181 gcatcttcag cgagttcccg atagtaggcg taaagttttg gtggaacgca atagaacgcc
     3241 ggttcgtttc ggttcaggat cgcaacagcg tccccttcac cttcagctac ggttcccata
     3301 ggattttttt tcaggtcagt aatactggcc gctgtggttg tcagaatttg atagctcata
     3361 agccctccgc ttgtctcatt ggcataatag catctttaaa agcactctta aaagtgctta
     3421 tgttgagaaa aacatcagaa caggtgagat atggctcttt ccgacatcgc cttaaaacgc
     3481 tctgtaacgc gttctgagcg ttttttcccg tttcgttgta gtcagctacg gtttaacggc
     3541 ttttaacgcc gctcaacgct ttttagcggc cttgttgcta tgatccggat aggagttcaa
     3601 tcttgatcaa aatttcctca aggcaacgac tgttttgtaa ataccctcta aaacgcgctg
     3661 tatcgcattc tgagcgattt tttcgatttc acatggattt tcttatggtt gtactgaacg
     3721 aagctgcaga aagcgattca gggcttctca gtggaagatc caaaaaggat caatcaacgg
     3781 atcgtatgat ctgaactctt ctggttttga gaaaggagac accgctcgcc gcagccgaac
     3841 gaccgagcgt agcgagttag tgagcgagga agcggaacag cacagggata acatcaggca
     3901 attacgcaca gtggttaaaa agcgagcata ttgtttttat gtgtggttgt cctggttcag
     3961 agtgatctgt cctctgggtt tacgcaaagt tatccacagg cactgtaaat tttttgtttt
     4021 gagcagagtt atccacagtt tttttgtgtt tttttgctta ttaaacttct tgtttttaag
     4081 atcttaaatg tagatcggta gatctacttt aagatcttta acttacttta acttattctg
     4141 caaacattgt gccagctttt ttatcaataa tttcattaag ataggtgttg ttttttgtcg
     4201 cctcaaaatg aaaggtggat gggtacgcac tgaaaggtgg atgggtacgc actgtaattt
     4261 tcatgaaagg tggatggctg cgcactgaaa ggtggatggg tacgcactga aaggtggatg
     4321 ggtacgcatt ttactgtttt tattcagata ttcatctctt tgcatcttca tttctttagt
     4381 tctttatagc gttccaatcc aacggtaaaa gttaaaaggt ggatacctgc gcatttctat
     4441 catattgaat ataaatgata aaaattcttt catgtgatct gtgttttggt ggaaatgtat
     4501 aaggtggata aaccacttta cacatttccg cttttgtggt tatgatttca ccatcaggac
     4561 ttaaaaaaca caggtaatgt atgaacttac tgagcgttac aaagaaaaca aaaattcgcc
     4621 acagaaatga aattaacagc acattctcat cgttgccttt gtctgccaga agaattttgt
     4681 ttatggctat ggcgcagatt gattcacgtg aagagttatc tgagggagca acctttcgta
     4741 ttacggctcg ggaatatgca tttatcgctg atattgatgt aacaggtgct taccggcagt
     4801 taaaagaggg ggcagaagaa cttcaggcta gtgttattcg cattcctcga aatcaacttc
     4861 tcacagctca gggcaatcaa agctctggac atacgaagaa gagaggtaaa ttaccttctg
     4921 atgcagtcag gcttatgaac ctgactgcgt tttgtgatta tgttgaaagt gaaggatata
     4981 ttgatattgc tttttcacat gtcattgagc catatatcac gatgttaaag gattcttaca
     5041 ctactcaggt tttgatatcg tctgtaagac tcgctgatca aaattcaaat atgctttatc
     5101 agtttatcag gaaacaatac agcagtggta aaaagacatt tttcgacatt gaagtagatg
     5161 tattaaagga tgaacttgaa ttattcagaa tagataatgg cgaaaaagtt tacctttatc
     5221 agaattttaa ggattttaat aaggtttttc tgcaaaaaaa cattgaaaaa ataaatcaat
     5281 atacagagat taatcatctc gaagttaaaa ttattgagag agtcgcaaga agagcatcaa
     5341 agctaagatt ttcgtataaa atagataaag aaagcgaagg acttgatacc agaataccgt
     5401 atggtttcag aggtgcttaa tatataaagg taaatacact atggagcaaa taaaattaca
     5461 taaacaaggt ggtgcggcag taattatcat tcctgccagt atgatagaaa ataccggatg
     5521 ggaagatgga accttattgg atgtactaga aataaatgag gctcttcata taagaagaaa
     5581 gacaggatca ggagctttag ctactaaatc ttgtccttct cttttttcat ctactatgag
     5641 gcatgttaac tacgataaaa tcattagata taatagcgga ttaaatctgt tagttaatga
     5701 actgtcattt tcggcaagaa ggttcttttt tatttgttta tattattact ttgaaaataa
     5761 acttgaatcg gataagtcgc tattgatccg ggctgataag tatgcagaat ttgttggtgt
     5821 tgatcgttct gtcgcatata agcaaatgaa ggatgcagca gatttctttt caagaaataa
     5881 aaaattaatt acacattgtg actatatttc gaatgaggga ttgcttcgtg ttatgttttc
     5941 gtctaagacg ataaattata ttacagcgat agacgcccgt aaatatcagg ttaccgagct
     6001 tcctctaaaa tctgctttgt ctcttcaagg aagatactca tggcctttat atcaactgat
     6061 aaaatttagc catcttaaat ctttcactat aggtgtagat gaacttaaga aagaaatagg
     6121 ttatattcaa aatcaaaagt tttctttctt taaaagagat ggaatcaata tagctattga
     6181 tgaaataaca gaaaggacag atgttaaaaa cattaaatgt gttaatgctg aaaggcaggg
     6241 tagaagagtc agcaaagtcc gttttgagat cgaaatgagg taactcatgg ctaaaatcta
     6301 tcaattcccc caaggggacg aacgcggtaa attcagggaa gaaatcgcca gagaacgtaa
     6361 gaaacgtttt gcggtgaaaa cagggagcac ttttgttaag tggcttggat ggacctggtt
     6421 ttatcttcgt cttctggtcg ccagtgtttt acattttatc tctgtttttg tgttagccat
     6481 tcttggcgcg tttaaatggg ctgtgttctg gctgggtggc attctgtgtg tcataacctg
     6541 gtatcatctc gatcaccagt tatggacgcc acaaaatctg actataccgg tgattacggc
     6601 aacctggatt tttggtctgt tggctgaacc gctgatggag ctgctcaaca aaaccatgcc
     6661 ctggcacaag ttactggttc ccgaacctgc gggcgaaagc acagagaaca gcagcgagac
     6721 gagccagtaa tgacgctact tagtcgttat gccagcccct gccttttcac tgcgatgcag
     6781 gatagggcaa acaccgcaaa atgacgtctc tgacgccatt ccgcaacgtt tgcccggtga
     6841 cctacagtcg gttcttgtcg gagaatttta tgaaatatca ggtgagagaa tttattactg
     6901 ataaatatgc gaaggctgtt aatattttaa aggataacct taaagaaaac taccatgttt
     6961 tttatggtgt gagattaagt gagattcttt ttccagccag tgagtatggc actgatgctt
     7021 tctttaaaga gtttgaatta attaacagtg taatacttcc attagtaatc tttgatttaa
     7081 cacaacgcaa gccaatgatg attatcagct tcgataagat acctgatgcc agtttgttgg
     7141 aaggaacaaa tattgtggtt cttgaatgta ctaccctcgc cgatcttctg acaaatgata
     7201 acattggttt tttatataaa agctaagaat ctcctctcag tttatatttt ctgcttgggt
     7261 tgccaagtgt tatcgagtct agttcatgtg agtaatgata tgtatgataa tgtgctggat
     7321 ttttcagata atcagggagt gatattattt tcccgtagct aattgcagaa taaaaccagt
     7381 tgcggaatgt ctcgctgttt gtttttaaag catctttggg aataaatgct aattttatgt
     7441 tagaaacgta attaacaggt ttaagtgtgg tatgcctatt ttgtccaaag tcttttaaag
     7501 catctgtaaa ttcatattct gatgtataat tttctgtctt attactaggg tgttttatct
     7561 ggaatatgaa tgaatagtag ttctggccaa gtatttcaac ggtgtttgaa tttatgctca
     7621 gttgttcaat aaccgcttct cttttatact ctaatttgtc tctgacagat tgatatacaa
     7681 ccattgctgc atgatgtgaa ccaccactgt ttaaagctac atatcggtca agccaagagt
     7741 aatatttaac attaatagga tcgcgagggt tgaaaccttc atgctcaatg tgccatatat
     7801 tatcctccca gtctgaaatg ttttcagctt tcaggttttt ggcgggatac atcccttccc
     7861 cccatgaata aaggtttttg aaccaactac catttattac tttgttccat ccacaaccga
     7921 aacttttcga ggcagtcaga gactgtatct tgttaaaatc aaaatccaga gagtggtttt
     7981 tatctgtagt tattatgtta ctcagaattt cagccagatc cctgtcaata tatcttagtg
     8041 agtattcgct aaatatattt tcaagctgca atatggtgtc tgcatccgct gtaggttcaa
     8101 ctaacttaat atcagcaaga tttttaaacg ttgcagcggt cagtttatgg tgatctgtca
     8161 acctgtagag ttgacagatt aattcggtta aatatctcat agataatcat ccatacttct
     8221 atggttagaa ttttgccgat tccagtaacc agtgattctt tatgttttca tcctggctgt
     8281 tgtacatcgc cagcgctgct ttgagaacgg ttgttttgct ctgccctgtt ctgatagctt
     8341 cagcttccag tatgtcctca aaatgggctg aaagtctgaa gttcatcaac tttggtttac
     8401 ccactacagg cgctctggta gcgccggaga taaaacgcgc ggtttctgcg tttgttgctg
     8461 gttgctgaga ttcatcgatg ttcggacggt ttagttttaa agccatgaca atttcccctt
     8521 gtacggtatg cattaatagt aaatatcata ctgtctttat attgtcttta caatgtaaag
     8581 atttatagat ggtattgata ttactataaa attccaattt cctgcgctac tagttcaatc
     8641 tgtgctttcg ctgttgaaag gcttgatgcc cggctaacgt catgtacccc tgccccttca
     8701 ttacaggcgc tttcatacac atccagctcg gatatccggg ttttaagagg ttgaatccag
     8761 atgttgtccg accgcagtaa tttatccaga tcaatggccg cttttctgtg gcggggtttt
     8821 gctgagttga ttctggtgaa cagcacccac ggttccaggg ctgcgttagc tttctgagcg
     8881 gtgcggattt tctctgtaac actggtcagt gtttcgcttt cgaaatcaga ggacggctta
     8941 accagtgtta ccacgatatc tgatactgtc agggcgctac ggaactcctg gctgtcgtgg
     9001 ccggggcaat cgacaatgag gacttcacac agcttactaa gtcgcttaat ttcattgctg
     9061 acgtttccgt aagctgcgtg aaccgggata gtgagtaagc cgttatctgt ccgcttttcg
     9121 ttccagctca acagatcgtg gtttttatct gtcttgagga taattaccga cttaccttta
     9181 ttgaccagca ttgagcctgt gttagccacg taggtacttt ttcctacacc acccttatct
     9241 gatacgacaa gcaagatttt acccatttga gaattcctct ctttacgatg taaagattat
     9301 gtaaagatcg tcttgtcttt acattgtgtg ttttccgtaa agatgatttt gtctttacag
     9361 tgtctttata ttacatagga tttaccatgt aaagcacaaa taaagacaat tatgtattta
     9421 tgttgtcttt atattgtaaa gattagtgtg tctttacagt gtctttatat gataaatcag
     9481 cacttgtctt tacatcatct ttatgttgta aatttccatg tgacattgtc actttatgac
     9541 cagaggtctg ttttctggtt cttttagagt gtgcctttcc tgtcgatcca ctttctggtt
     9601 cattttgggt atagttgtgt gaccttatgc gaactggttc tctaatatga cttcaaatgc
     9661 accaacaaac tttgtccgcg cttatctgag agcttcaaca gcagaacagg atgcttcgcg
     9721 tgccctggaa actatcgagg cttttgccag ggaaagaggc ctgatcattt gcagctatta
     9781 tattgagaat gaatccggct cccgtcttga ccgcccggaa ctcttccgtc ttctgagaga
     9841 ttgccagcaa aatgacattt tgcttatcga ggatgtggac agactttccc gactgtcagg
     9901 ggaagactgg aatacgttga agaaaatgat ccggcagaaa gacattcggg ttatggcggt
     9961 gaatgtgccg acgacatgga ttaattctgg tatgagtgag tttgacagcc ggttgtttgc
    10021 agccattaac gatatgctgc tggatatgct ggccgcagtt gccagaaggg actatgaaca
    10081 acgtcgggaa cgccagaaac aagggataga gaaagcaagg aaagacggta aatataaagg
    10141 gcgtaaacct aatcaagcca gacatgatgc aattatcagg ttgatagaaa gcggtagctc
    10201 ctggacacag gtacagaaag tgctagggtg cagccgtggc acaataagca gtgcgctaaa
    10261 acgtaaaacc gggcaaaaat ccagtaagta gagggggtgg ggggctaata tatctgaaag
    10321 gcaggatatt aactcaggag gttgggtgtg tggtgtttag ttaatgcatt tgaatgttgt
    10381 aactaaaata tgattttatt aaaggccggt ggtggttagc ccccggcctt agttacgtct
    10441 ccgccatcag cccatcaact ggagaaggta gcgaatcagt tcaagaagcg agattagcgc
    10501 ccccagaacg atgccgttac cgacattatc atgaatcccg ttttttcagt aagttgcagc
    10561 atacaaagta attaaaaaaa cgtcattttt tgttgatgga tgcagtagcg gtggtgcgct
    10621 acgtgaaatc tggaaaatgt tggcggggta agtgactcaa tttttaaatc tccgctcctg
    10681 ttttttgggg atgtgtcagc aattatgact tggagcaaag gtgtgtccga caacaaaaat
    10741 tctgatcaca aaaaaatttt ggacattttt tccgataatg catttttgtc catgatgaat
    10801 gaacgacagg gcagggaaag tcgcgcaaga ggcagcggac tgaatcagcc cttcacacac
    10861 aatggcacac ggaaagacac gtttgtgtct gtcccgaaga gtgtttctga aatacagggc
    10921 acgacagcga tgtatgcacg taataaattc cgtgtataaa cgacgcgctc agggggggga
    10981 atccctgata cccccgctca gtttctgcaa aagttcgctg tatggaggtt ctacgaacca
    11041 tgatatttgt ttctattgat acggcttaaa gctaatgtac gcatacatta gcattaatcc
    11101 agagaataat acatgagaga caaaaccaga gaagctatgc gtatgtttct cggtggcaga
    11161 tgttacaccg ctgaaaatct tgaaagggat ttcctttcag aactgaccag atacagcgat
    11221 gaacgctggg aagccccgca acgtggcgca cgtctggcgg cagcggtgaa gcgttacaaa
    11281 acctcggaaa tgctgcggtt tatttttgcc accatagcat atgaccctga cccggattta
    11341 acaccgctgg ccgttaaacg gttgtgcaat gcgttgtttg gcagaacggg gagccagtgg
    11401 ctgattgtgg aattattcgg ggataaggag cggcagcacc gcagcaacga cagcaccctg
    11461 gaggccgtgg aaaaaatggc tgccagatat cgtcatgcgg caagacagca ctgggcggca
    11521 acgctggacg aaattgaacg ggtaaagcgt ctgtatcagg agggaatcaa ggcatccaga
    11581 aaaaaagaga gttaactccc tccccattaa tgctagtgta cgcgtacatt agcattaaac
    11641 ctccagccac acacaaatcc acatgtttcc acccgtccgg tggttaagtt ccctgccgta
    11701 aacaccagtg aacgccgggc aggacgaaaa ggaagcgatt atcctgaata acctaggata
    11761 tgggcacata tgccggaaca gggcacagga taaaggaact aaacatatga atgttgtaac
    11821 taattgagtc taaacaaaaa aacaaaatgt ccaatatggg cgggggatta ctaaaggagg
    11881 ctattaatgt acaattggtt ataaatttta catatgaaga taagggaaaa aaatgagtgg
    11941 acgaatcaca accttatgca ctgcatttgg ggtggttatc gcagcagtgg gactttacct
    12001 accatataaa aatgaattga atgctgctct ttatcaaaga gaattcctta ccggaaaatg
    12061 gtcaacagat gctgaatata ttattaatag tggggatctt ggactagata aaccgcaatc
    12121 aattatgact atacaattat ttgttgataa agatggttct attgatggtg aatttatctc
    12181 agaaggatta tgtgatgcaa tgcctttgac gtggaatata acttttaata gtgacagtcc
    12241 atctctaatt aattttattt ttgcgagaaa attccaaatt agacaactag ttaacggggc
    12301 aatggataaa agccctgttg tagctacatt aaaattagtt gatgaagatc ataaacataa
    12361 tccgatagtg tttgatgtgg tcaacgattc taccggaacc ttacctaaac agatcacttt
    12421 agctaaaaac cttccgaaat tcgaagaaaa ctataaatac ctacagagtt attgcgctaa
    12481 ctcaactgaa aagatgtacg aaaagatgat gccagagatc aggaatttga acaaaggttt
    12541 ataacgtttc ggtgctagac agaaaatgct gtatgtccag tcagccggag aattatacta
    12601 gcgaccatga tcatcacagg aagaacgtgt aacagatggc aactgagtgg gtagatgtgg
    12661 ctgataatgc cgttaaaatt gggctgggtg cattaatcac cattgttggt ggctggatta
    12721 cactgaaatt aacacactgc cacgaaataa gaaaagatgc aatagctcag cgactgcggg
    12781 atatagataa aaaaactgac cgctatatag attttctttc ttcatcgcaa acgctaatgc
    12841 agaaatatct ttatgaatca tgtaatccag gtagcgagga ctacaccaat tatatgcggt
    12901 tacataatat tgtaagcctg acatcctccc ctgaattgcg aatctatgct tttgatactc
    12961 agtccaaagt atcgcaattt atcctgctca gaaagcccaa cgaaccagag gttattgatt
    13021 cctgtcgcaa tgccgcgaga aacgccgttt ctgtgcttca gggggcagtg agtgctgaat
    13081 tgcttcagga taaagcagca cttcaggaca aacaacatgc atggtgggct ttctggcgaa
    13141 aataaagcag aacagtggag gaagagccat ttctccaagt agcgaaggac agttaaagcc
    13201 ttgggaaaaa atgtcgataa tccgagcaac attctatcgt aggaagaaaa atggaaatag
    13261 tatcatttaa agtttctcag tataggtcta tttcagggga gatatcctct gataacttta
    13321 atggattaac cattgttggg caaaacaaca gtggtaaaac aaacctatta aaagctatga
    13381 gggttttttt tgaaggaaaa tttaatcctg acttatatga ctatgaaaaa gataagccac
    13441 atggtgttaa gcaaggacaa actagttttg ctgtaagatt tactttttct gaaagtgagc
    13501 tagatgatgt ctctgaggat ttgagccaag acgatgatga tgacgatgat gactcgatta
    13561 ttgaacttgg tgttttaggg gggcaagaag aacctagtaa ttctatttca tttgatgatg
    13621 gcagctctaa acaacaagaa tcaaaaccaa ctcaatcaag aggcagaaag ctaagtttga
    13681 gagatagata tttgcagcta tttaacatga ttgatgactc caggttaagt tcacctcaaa
    13741 acgaagtgac cgtacatctg acaatatcta ataaaaacaa ttacttctac actgtcttta
    13801 aaggttacaa gaggaaacct gaagtaactt cctccatgta tacatctgtt gaaagaaggt
    13861 tcatagaaaa aatactttct agttttgagt gtgtgtatat accatcgtca aaaagtattg
    13921 atgatatata tcataatcta ttagttccat atgttaggag tgaagtagct tcagccatga
    13981 aaacatcggt tcaagtgatt catgataaac tgttggaagt gtctgaaaag ataacaaatg
    14041 aaatgattct aagcggtata gatgactgta gctttatgat taaagctccg ccatctcttg
    14101 atgagttatt tggtcgcttt gaggtttcaa taaaagatac tattgagaat gtgatatcga
    14161 gtaaaggtat ggggctacaa tgcttatctt tattttcttc atttaaatct atttcagaga
    14221 gaaaacttac tctaggtaag aaaacgattt ggatggttga ggagcctgag tctttcttgc
    14281 atccctcatt aggccggtca tgtaatcaca ttttcaaatc actgatggat gttgcttatg
    14341 ttcttattac aactcattcc ttatcatttg tcagtgatga gccaagtaag atcattgagt
    14401 tatataaaga tgacgccggt gttacaaaag ataaaaagca tgaaaaaaga tttaatgcag
    14461 ttgcaagcat aagagaaaat cttggggtca gattttctga tttctttaac atatcaagta
    14521 gtgcagtttt cgttgaaggt atcaccgaca aacaatatat agaatcaata ttgaaattga
    14581 catctgaaca tgatgagtta aagaacagat ggccttttct gaggagtgct aaagttgatg
    14641 agtttggtgg agtcagtcaa cttggaggat tcttgaaagg gtgctacgag tttatttcta
    14701 aagatgtccc cgtaatatct gtttttgacg gtgatgaagc tggggtcaaa gaaagaacca
    14761 gattacaaag ctactttggt aaaaaacaaa ttagatttga gtcaaataaa gactatattt
    14821 ctgtaagaag tggttttgct attgaaggcc tcttccctga cgatttcatt tctgacgcaa
    14881 tggaaaccca tccgtcgtgg tttatcggag gaaaatctgt tgatgccgat gatgtaattg
    14941 aaccattcaa agtgcaagat aataaaaaaa ctaacttatt aaatttcttc ctggaaagat
    15001 gtcgtgttca acctatatgc ggttggattt ctcggtggga aaaggtgttt aacgtcatag
    15061 actcagcctt gcgagataaa agtgaatcca tcacaaacaa aaaacgaacc gaagatactt
    15121 ccggtaacac ttcagatcat caagctgcat aatcgattgt gtacaccaag gttgtacata
    15181 cacctgatta atcaagagtg agaccataac aagcctatat cagataacag ccctcttcat
    15241 aagagggctg tctttttcgc gggcatcgta cttgggtttc acttggaaaa tggaaaacat
    15301 cctacgctaa gagcgttttt taaacaaccg gcttgttggt ttttacgaga tactgtgcag
    15361 ttgaaggaac aagataaagg aattaaagac cctttagtac catactttca tgaaattttc
    15421 ccatattttc ttttagatcg tgcaacagcg aaaagacgta ggaattggct tgattagccg
    15481 caatactatt tctggacaga atgagtgtat atccaagtcg ggcgaggaat taaacggggg
    15541 gcgtaaaaaa ggccgcttac gcgacctcag ccttttgcgt ttttggcttg gtgatatacc
    15601 acgatagaca accgacaata aaactcatga acattccagt aaaacgatca tcaatgccta
    15661 gaaacaggca accgacaaac atcgcaacag ggaaaggaag aagtaaacag cgccccaaaa
    15721 tgctcataaa atccataaat cctcctttgt taaagggcag gaagcggttc acttcctgcc
    15781 cttagttacg tttccgctgt catcagtcga tgaactggcg aatcagttcc agaattgcaa
    15841 tcagcgcgtt tgcaacggcg accacagccc tgagaacgat gattaacaaa ttaatcatcc
    15901 gtttctccag taaaactgga ggaaatcacc gttgcttact catacactgc ctgtcacaac
    15961 ggctctctcg cattgttagg tgtagagtga cctcctcctg ccagagcacc gaatacagca
    16021 ccacctgttt atccagccag gactttaaaa tcgttcatac ccgcagatac gggaagagca
    16081 ggattgcaag tcaactgcat gactaactga ctgattatac gctacacaaa acacccgtta
    16141 caccactaaa tgtggttcct taaccacatt tagttgcttt acagcaccat agtgaataaa
    16201 atgtaaacgt taggtgtaga gtaaccttct ccagtcagag ccaccaactc agggctggaa
    16261 aacacaaaaa agcccgatta ccagtcgggt ttttttgtgc ctgtcgttca gctgtacttc
    16321 cgttttttcc ccttcatttg agggattttt ctttcatttt ttgttgcgac caatactgct
    16381 gatcgcgttg gccaacagat caataccgtt atcggcgttt tcatgaatcc atttttttca
    16441 gtaagttgca gcacaacaga tgattaaaaa agctatcagt ttttttgatg gatacagtag
    16501 tggcggtgcg ctacgtgaaa tctgaggctt ttcggggggg attggacgag aaaatttacg
    16561 agagaacact gcgattttca aaaaaagccc ataaactgaa agtgctactg acatatctca
    16621 aaacgggttc attttgacac taaatggaaa ggaaaaatcc tcatgatgat acaatctcat
    16681 ccactactgg ccgctcccct ggcagtagga gatacaattg gtttcttttc atcatctgct
    16741 ccggcaacag ttactgcaaa aaatcgtttt tttcggggag ttgagtttct tcagagaaag
    16801 ggatttaagc tggtatcagg gaagcttacc ggtaaaacag atttttatcg ttcaggtact
    16861 attaaagaaa gagctcaaga atttaatgag ttagtctaca atcctgatat tacctgtata
    16921 atgtcaacga tcggtggaga taacagtaat tcactactac cgtttctgga ctatgatgct
    16981 atcattgcaa accccaaaat tatcataggt tactcagata caactgcttt attagcagga
    17041 atatatgcaa aaacagggtt aataacattc tatggaccag ctcttattcc ttcgtttggt
    17101 gaacatccac ctcttgtgga tataacatat gaatcattta ttaaaatact aacaagaaaa
    17161 caatcaggaa tatataccta cacattacct gaaaagtgga gtgatgagag cataaactgg
    17221 aatgaaaaca agatattaag gcctaagaag ctatataaaa acaactgtgc cttttatggt
    17281 tccggaaaag ttgaggggcg tgtaattgga ggaaatctaa atactttgac aggtatatgg
    17341 gggagtgaat ggatgcctga aattcttaat ggagatatat tgtttattga ggacagtcgg
    17401 aaaagcattg caacaattga acgattattc tctatgctaa agcttaatcg cgtgtttgat
    17461 aaagttagtg caataatact cgggaaacat gagctttttg attgtgcagg aagtaaacgc
    17521 agaccatatg aagtattaac agaggtatta gatgggaaac agattcctgt actggatgga
    17581 tttgattgtt cacatacaca tccaatgcta actcttccac ttggtgtaaa attagctatt
    17641 gactttgaca acaaaaatat atctataaca gaacaatatc tatctaccga gaaataaata
    17701 ttatcatctc acagacataa acaaaatggc gtagaatact acgccataca gtattaacca
    17761 attacttttg aataaatatt ttgatcgtat gatacaccgt tgagtatttc tgctttttgc
    17821 agaacacctt ctaaggtgaa gccacacctc aatgccgtgg cattactttt tttattatca
    17881 acaatacatt ttataacaaa tctttttata acgcccgaat ccccatactc ctgtatcagt
    17941 ttatttatag cattggttac aatccccttc ccctgaaagt tagcacctaa ccaatagcca
    18001 atatatgctg ttttattggc atggtcaata atattaaacg atacaacgcc agctatctta
    18061 gttttgtatt taataaagag gattaatgct ttttcattct ggttatcaat cattgattgc
    18121 tcaatgaaag aaacagaatc agaaatgtta ttaacaaacg ctggccatgc catgctttta
    18181 atgaaattta ttttgttttg attaatgagc aaatataact cttcagcgta ttttaacgct
    18241 ggatacaata atgtaatttc atcatttact tttattcctg atggcgtaag agatacatca
    18301 tacttccgga aatcaagttc tcttctgtga atccttgata tattaacaac atcatttgtt
    18361 atggtatata cagcataaag attacgcgtc cactggtttc ctgtttgcat atcataagca
    18421 ccacaccctc gaacagaaaa taaataatca gataagttac tgggaagaat aactgaagga
    18481 aacaagcaat cacattcaaa gcaattgaat ccagcaataa tatactcatc agatttatca
    18541 tctgaaatat ggttatgatt atgaaacaat gtaaatgaat ggtcccaatt tctgatcgaa
    18601 ggtatccagt ttataccaat gttagtttga gcaactttaa caccatacct gtttttagta
    18661 ctaataactt tccctataaa gtagccaaag tcttcgacca gatgtctccc tggttcaaaa
    18721 atatagttcc atttatcaca tacagtaccg aagcaatttt ttattgtatc atatatcgat
    18781 gagaaaaata cctccggaca tggagttggg ttatcactgg atgctgagaa agaatctgca
    18841 ggtatcccac taccaagatt aagagtgcca tcatctggca tatacctaag aatcaactca
    18901 tgatactgta taatagcttt acatattttt tccgcattgg gtagattaga gccaacatgt
    18961 aaatggaacc cgtctaaaat gagatactct gacttactga tcaacatctc cagtaaatta
    19021 atagcctcac tttcagataa gccaaatctt gataaattat catcatagta atgcgataat
    19081 ctcaaatgaa ttctacatgt cagcttatgc aacttacata gttcattaag tcttttacat
    19141 tcatcaatat tgtcaacttc aattaatgcc ccaatctcta ttgcctttaa tagttcactc
    19201 gtttttttta aagggccatc aaaaacaatc cgcttaaaac cgtctctttt ggcgaggttc
    19261 atttcatcaa cagagcacac ctctgcatac aaacctttac ctgagataat ctggcaccat
    19321 tgtgccagat tatttgactt atatgaatat gcgatactac tgttggggaa aaaactctta
    19381 agttgacacc tgtaatgatc cagacgctcc agagctccat ctacatcaaa aatgacaaat
    19441 gagttttcgc ccgattcaat ccccttaata attaactccc gggcatgttt aacaatttta
    19501 gatggtgtta ttttttgcgc catatttgca atgtaactcc ctgataatct ctttggatat
    19561 ttaatggtct gcgtattttt aaaaatcttt caaaaaatac attctgaagt gaaccattca
    19621 aaccttttgt aaactcattt ctattgaaaa tgtaatcata aatatcggct tttaactcat
    19681 cttcactttg agattccatc tcatggtttt cttctgaaac aagagtaaat ctttcagaaa
    19741 aaaactgatg ccagtattcc aaagtccaca aaggattggg tctgaaattt attgcattat
    19801 atacatcatt gataagttta tctgatattt tacgcctgta ataaaaattt gaaatgcaca
    19861 tgcttcccat gtggtttaaa catcgatgag tttcattcaa agctattaac cgattttgta
    19921 taaatgcaaa attacatcca ccgagaacat gtgtaaaaga gttatcttca aatggtaaat
    19981 cacaagcatc agctacataa tatttcaata aattattagc cttaagcttt tttgcctttt
    20041 catttgcgac cattacagct gattcagata tatcaatacc ctctgcagat gcaccttctt
    20101 ttttgaagca ttcacgtgaa ctaaaacccg tggaacatgc taaatctaat aggtgagact
    20161 ttttgttaat acatccatgc ttgatccagt agtctatggt gtactctgct ccaggaggag
    20221 tgttatcctg ttgcatcaga gcaacaaaat cagggtaatt catatttaaa ataacttctt
    20281 ccgtcaattc ttcagcatgt ttaatcgtca taccatctcc tttttaaagg accacattaa
    20341 gaacaaacaa ccgcacagta cacatgcaat tgcagagata aatatataag tggtgacagg
    20401 catattacct ggtaatacag atataactcc caacacagaa atggaagcaa cacgacatga
    20461 aagagaaaca agaccaagag ctcccgaaat aatattctta taattgccat taagtctgct
    20521 tatgaatata ttctgtgctc caacaggtat tgttgaaatc atcccatgga ttatagagaa
    20581 aatagctacg ccgagaacaa ccttattatc tgttattaac ataaatagta aaatacaggc
    20641 gattgaacta agaaatgaac ataatgtaca aacaagtata taaagtttac accttacatc
    20701 tatctttggc ataagatagt ttgctatata ttgcattgaa aatgcaccaa tatgacacat
    20761 cagtaaagtt ataagctctc tttttgataa tgagccaata ctttccccag atagcataat
    20821 tggctgccaa aaatgataaa ttacctgtat accaattgta aacatacatg ttatagataa
    20881 aaaatatgtc ccattataac ttcctgttat caatccaata ctctcttttg cctgtttaat
    20941 aatactatct cgtgcttctt tttcacctcc actgccatta gttttcacac ataaaaaaac
    21001 gataaagaca acaaacatca agaagaacga tactatatag ccagatttat aagaatcata
    21061 gaagtagaca actaatattc caacagcacc agttatcaca cccccaaagg aagataccct
    21121 ttcgcataaa tgagcacata aggtaaactt ttcatttcta ccatccagag cacttaacac
    21181 ccatccctct atagccccag atatacaaca aataccaatg gcataaaata tttcagaaaa
    21241 aaccaatgcc agcatatcag gagactgaat acaaagaggg taaaataata tagtaaaaaa
    21301 tacgccacta actacaacct gtttcctgta aaatctgtct gcaatgacag ataaaggaaa
    21361 atcaagaatc agcactgtca cagaaaaaac gatctgtaaa acagcaagtt gagatatagt
    21421 gacacctgta gatataagaa atgctgcatg gtagacacca attaacatac gtatagcatt
    21481 ataagctcca tagttcacag ataaaatatt tgcagtattc acattctatt tccacacaca
    21541 gagcaaacag gcgaacggcc catattttgg gaatgtattt ttatttcatc tgaccagatg
    21601 cctattcttt tattaagtga taatggctcg gagtattttc caatgaactt aattacgtct
    21661 gccgcacata atgcagcggc aacattattc acaggtgcaa atgttgccgg tttaaatctg
    21721 ctattgatta gcttaatctt atgatcaatg ttttcctttt ctgaaccata tagatctgcc
    21781 acgacttttt ggcactcata acatcctgtt ttaccaggaa catataatgg accaaagact
    21841 gcaatatcat taacataccc agcatttata tagggctgat ttgctctaac gcaatattta
    21901 ttaacccagt taatcagatt aaatggatga tctgcagaaa caacccatat atcagcttct
    21961 ggtaccttat gaagatcagt gtaatcgttt atattcaaag cgatttcaga caccgaaatt
    22021 tcagagtttc tttttaataa ctcgcgtttt ataacttctg ttttattttt accgacatca
    22081 tcctctgaaa ataaaacctg ccttgtcaaa tttgtatttt ctatttgatc attatcaatt
    22141 agtataattt cgccaatacc agacgttgcg agtataacag acacatgatt tcctataccc
    22201 ccacaaccaa gaattactac cttagcattt tttagtttat cttgcacaag aacaggatta
    22261 gcaccataac tttgataatg taaaaagtta cgagagtaac gattattctc agtagagtta
    22321 ttatactcgc caggtataat aaagaaattt tccttaagga acctaaagca attagagaaa
    22381 tctttttcag gtatattggc cgtttccaac gctgcagtat aactcgatgg ggttatgaaa
    22441 caatatgcgg tttttataat attttcccaa agcgctaaat tctcaacata ttgctccttt
    22501 ccgcctccac caactaatcc accgctcccg tatcgagcaa ttttgacata gcgacccaat
    22561 atataatcca taaataaacc tcgcagataa cttttgtatg ccaccctgta cagggtggca
    22621 tttaatggac atttatattt ttccattagt ttgcattacc agtacgcatt ttacgcctcc
    22681 tattactgtg attaattcac aagtgttttt atcactataa aaaacaatat tccttataaa
    22741 aatatacaaa catagattta tttcacaaaa aaagaacagc acaatcatat tatttgcgat
    22801 tctacatttt tattctaaaa tttattaatt tatatattta gacataaata accatacaga
    22861 atataatcat ctgcgtttaa atcattttgt aataaatatg ctattatgca ataaaagaat
    22921 ttgatacatc catcgttcat tacattggaa accaataatc ctgattacca gtcacgttga
    22981 gaagccgctc aatgagcggt ggtgcgctac gtgaaatctg agttttttcg ggtgggattg
    23041 gacacgagaa cttatgagaa agcatcagga aatacaatga aaatagagat taattttcga
    23101 tgaaaggcag ctcgcaatcg ccgcattcaa tattcagtcc ggacttctcc cagacagcag
    23161 caccacaccc cgacactgat atttgacttt gttccttttt ggcttgttct caaaagccgc
    23221 aacaaacaga tcgttatcat tgctcccgtt ctacggtgac actgacagca ccgcttcaat
    23281 atcaatcccg gttcagcatt ttgatgtgcc tgagcaatag tttcccgcca ttgttcgatg
    23341 acggcggcca tctctttttg ttgttcaacc tggacagaga agcgatcaaa ccagctcaaa
    23401 gcaaatttcc cctgaaacag atcctgtgtg acgcgctgga acgtaatcag acactcgggg
    23461 agttcaccgt caaaaaggcg ctggttatag aaatcaaacg cctgttgtag ctcgctgtag
    23521 cgcgttctgt ggctatcgtc atcatcagga ctcctgaaag acaacccagc atttcgcgcc
    23581 gtcatattca ttgccacttt ctgcaataaa cacgttatct tcagtatcta ccgctatcac
    23641 tctggggcgc tcatgctgag gggcgcggtg aatatttttc cagcaataca cctctccgtc
    23701 ccaaatcaga atcacacccg aatcagcgtg ccccgggttg tgctgacgcc atcccctggc
    23761 aatatcaagc ccagggagag catcgagcgc gtaatattgc tggcaagaaa ggtaagcagg
    23821 gggtatccct gctttatgta acagaaatca agcactgccc catgagccat gtttcaggca
    23881 ttgctggtaa aagacactta gaagctcttg ctctgttggc ggttcttcgc cagaaattcc
    23941 aattctggct gggataaata cgttttcgtc tttccctgcc agtggccgca attcatcaga
    24001 ctggcgcata acgttatcca acgcttttgc caactccgct ccattgctgg ccggaatact
    24061 ggtcagaacg gccattccac ctttaatctc gcgacgggag ccttttttcc tggcgataca
    24121 cacaacaaat agttgtattt caggttgcaa ccatgcctgc tgaacaaagc cgtcctgata
    24181 gtgca
//
