LOCUS       NZ_CP063521            24093 bp    DNA     circular CON 17-JUN-2023
DEFINITION  Escherichia coli strain EH01-18-02 plasmid pEH01-18-02_3, complete
            sequence.
ACCESSION   NZ_CP063521
VERSION     NZ_CP063521.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN16387489
            Assembly: GCF_016944775.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24093)
  AUTHORS   Moser,A.I., Campos-Madueno,E.I. and Endimiani,A.
  TITLE     Complete genome and plasmid sequences of MDR Escherichia coli from
            local people and environmental sources in Laos
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 24093)
  AUTHORS   Moser,A.I., Campos-Madueno,E.I. and Endimiani,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-OCT-2020) Institute for Infectious Diseases,
            University of Bern, Friedbuehlstrasse 51, Bern 3001, Switzerland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye v. 2.7.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 983x
            Sequencing Technology :: Illumina NovaSeq; Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 06/17/2023 06:20:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,803
            CDSs (total)                      :: 4,682
            Genes (coding)                    :: 4,484
            CDSs (with protein)               :: 4,484
            Genes (RNA)                       :: 121
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 12
            Pseudo Genes (total)              :: 198
            CDSs (without protein)            :: 198
            Pseudo Genes (ambiguous residues) :: 0 of 198
            Pseudo Genes (frameshifted)       :: 77 of 198
            Pseudo Genes (incomplete)         :: 123 of 198
            Pseudo Genes (internal stop)      :: 41 of 198
            Pseudo Genes (multiple problems)  :: 38 of 198
            Pseudo Genes (short protein)      :: 2 of 198
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP063521.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..24093
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="EH01-18-02"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="pEH01-18-02_3"
                     /geo_loc_name="Laos"
                     /collection_date="2018"
                     /collected_by="Institute for Infectious Diseases Bern"
     gene            80..430
                     /locus_tag="IQS16_RS23255"
                     /old_locus_tag="IQS16_23245"
     CDS             80..430
                     /locus_tag="IQS16_RS23255"
                     /old_locus_tag="IQS16_23245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000269927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_000269926.1"
                     /translation="MWTVYFGRLFDEWFEEQELALKRKVLAELKHLEEFGPSLSRPHAD
                     TVKGSRHKNMKELRIQYEGHPIRAFFAFDPIRQAIILCAGDKSNDKKFYDRMIRIADEE
                     FSTHLAELEGKK"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            427..726
                     /locus_tag="IQS16_RS23260"
                     /old_locus_tag="IQS16_23250"
     CDS             427..726
                     /locus_tag="IQS16_RS23260"
                     /old_locus_tag="IQS16_23250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_001259443.1"
                     /translation="MRTLEEVIAAQSPESQAIIKAMADEMILETGLQMMREELQLSQKQ
                     VADAMGISQPAVTQLEQRGNDLKLATLKRYVEAMGGKLSLDVELPTGKRVAFNI"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(757..1002)
                     /locus_tag="IQS16_RS23265"
                     /old_locus_tag="IQS16_23255"
     CDS             complement(757..1002)
                     /locus_tag="IQS16_RS23265"
                     /old_locus_tag="IQS16_23255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001193619.1"
                     /translation="MQTKPTPADVKEARISAGLTLKEAAEIFGYQLNTWQMKESAGKAT
                     RSLSVGEYNYLLLLAGKHPEYVLCKRDTITAEPTTV"
                     /name="hypothetical protein"
     gene            complement(992..1249)
                     /locus_tag="IQS16_RS23270"
                     /old_locus_tag="IQS16_23260"
     CDS             complement(992..1249)
                     /locus_tag="IQS16_RS23270"
                     /old_locus_tag="IQS16_23260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001350939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_244574854.1"
                     /translation="MKTDNVFFKSKGSYSYVVTVDMDNQMYMVRKYVKTYVKSCDKEQV
                     KGKKTVKKLVLDTNLTLPELLDLDNGILADLFKRGNNNAN"
                     /name="hypothetical protein"
     gene            complement(1285..1827)
                     /locus_tag="IQS16_RS23275"
                     /old_locus_tag="IQS16_23265"
     CDS             complement(1285..1827)
                     /locus_tag="IQS16_RS23275"
                     /old_locus_tag="IQS16_23265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_096950009.1"
                     /translation="MTTFSEKYQPVFEVVCRILGNGWRVNKLDNYQHRIKLTSTELRKY
                     SIIIRLERERFFIVGSVDSLVWHGNPSVCTVSLTRNPVGIANDISRKILANALDEIELL
                     GKHENALQKKQDKVQIIKGMLSQLISISPWYGALTGFNVDNGLTGKILQNGDDYEMVIR
                     GLNVDQLIKVAGFIKKL"
                     /name="hypothetical protein"
     gene            complement(1955..2488)
                     /locus_tag="IQS16_RS23280"
                     /old_locus_tag="IQS16_23270"
     CDS             complement(1955..2488)
                     /locus_tag="IQS16_RS23280"
                     /old_locus_tag="IQS16_23270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="WP_096950008.1"
                     /translation="MNIQEALNIFGLSGQLTEKDIKNAFKKAALKYHPDRNPVGAEMMK
                     AVNLAFDFLMANLDKINQYQSPEQSAIYNYGDELENVLKALYGLSGLVYEVIGNWIWIS
                     GNTIEHKEALKEIGCKWAAKKKQWFYRPEEHKSYWNREEHTIEEIRAKYGTSGKFQAGG
                     WQQVEGRARVEARA"
                     /name="J domain-containing protein"
     gene            complement(2857..3156)
                     /locus_tag="IQS16_RS23285"
                     /old_locus_tag="IQS16_23275"
     CDS             complement(2857..3156)
                     /locus_tag="IQS16_RS23285"
                     /old_locus_tag="IQS16_23275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_096950007.1"
                     /translation="MARLPYIESTTQQIFIFNTLTLCTIGLIHIETGKKYVVVFTDNNK
                     IRDYKNGVIEELGEIMQEDIELIEYYAKKYEKYFDNLKIGEESLNLKEYIECMQ"
                     /name="hypothetical protein"
     gene            complement(3230..3502)
                     /locus_tag="IQS16_RS23290"
                     /old_locus_tag="IQS16_23280"
     CDS             complement(3230..3502)
                     /locus_tag="IQS16_RS23290"
                     /old_locus_tag="IQS16_23280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001272119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_096950006.1"
                     /translation="MSAFIFRTTFKATGDQQKDAITQIEVMQEQAVKAFVSWMTSQEGT
                     EFLSTLQEITTELDALIDAVESHPPVFRKKATELEALLAHYKTLL"
                     /name="hypothetical protein"
     gene            complement(4452..5117)
                     /locus_tag="IQS16_RS23295"
                     /old_locus_tag="IQS16_23285"
     CDS             complement(4452..5117)
                     /locus_tag="IQS16_RS23295"
                     /old_locus_tag="IQS16_23285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001312457.1"
                     /GO_process="GO:0006276 - plasmid maintenance [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepA family replication protein"
                     /protein_id="WP_251326763.1"
                     /translation="MAKQSPCYNVVSRKRRRFLNRWIKSLTTVAGRIKIKNELRRRIRH
                     NRYWVNEANKFGIEALCELMLAILDDLDLRSWETRHNLETLAERAGLVTRSDAGHKSIS
                     RASRGCDRLVWLNAIITEKAPFNPYDARCACKHIEVTEDFFAILGIPLKLVYRERARLL
                     KADPDEVIYSGDARLIAIRVQNWTRKAAAGLARMKAKRDAARQRKKEYYADPPTPIPA"
                     /name="RepA family replication protein"
     gene            complement(5744..6109)
                     /locus_tag="IQS16_RS23300"
                     /old_locus_tag="IQS16_23290"
     CDS             complement(5744..6109)
                     /locus_tag="IQS16_RS23300"
                     /old_locus_tag="IQS16_23290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248966.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000248966.1"
                     /translation="MVPKRLKEARMEAGLSQEKLSQLLGVAEGINTRSRFSSYEVGRTE
                     PPFKLVKKIAELLDYPENYFYTEDDDFAKAVLDFHRKRTSPELNPNYDSEVEARRMASK
                     LDNVKKIVAQLNEYLKE"
                     /name="helix-turn-helix transcriptional regulator"
     gene            6363..6812
                     /locus_tag="IQS16_RS23305"
                     /old_locus_tag="IQS16_23295"
     CDS             6363..6812
                     /locus_tag="IQS16_RS23305"
                     /old_locus_tag="IQS16_23295"
                     /inference="COORDINATES: protein motif:HMM:NF014417.2"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination NusG
                     family protein"
                     /protein_id="WP_024192530.1"
                     /translation="MNAWYLLYCNNNDLDRIAYRCKTMNVVAFCPRYIKFTPRKDCNAV
                     RKEEKVLFPNYLFLHFDVNVTHTSAITSIPGAIGFVSFGSTICTVPEKVVIAIKCAKIL
                     ALNPDDDSIECRNIGSDLLAEIQRISSIISPLERQTAFSRLLQNQ"
                     /name="transcription termination/antitermination NusG
                     family protein"
     gene            6889..7101
                     /locus_tag="IQS16_RS23310"
                     /old_locus_tag="IQS16_23300"
     CDS             6889..7101
                     /locus_tag="IQS16_RS23310"
                     /old_locus_tag="IQS16_23300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001133545.1"
                     /translation="MPNPIGQAKSTAVIYIGKKRYETLAKHARDISYVAEVNIRPSAFL
                     QYMIDKLSNEAHNEMLKELMSKEDK"
                     /name="hypothetical protein"
     gene            7102..7308
                     /locus_tag="IQS16_RS23315"
                     /old_locus_tag="IQS16_23305"
     CDS             7102..7308
                     /locus_tag="IQS16_RS23315"
                     /old_locus_tag="IQS16_23305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001125884.1"
                     /translation="MPKPTYNVYVTQEVPTDENGGKNTYWTKVGAAFAHNGKPGLNIML
                     VPGIAVSGKLVLLEPKEDAPQGN"
                     /name="hypothetical protein"
     gene            7324..8028
                     /locus_tag="IQS16_RS23320"
                     /old_locus_tag="IQS16_23310"
     CDS             7324..8028
                     /locus_tag="IQS16_RS23320"
                     /old_locus_tag="IQS16_23310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_000953547.1"
                     /translation="MLSTVSFMAVAMQCAATVHPSTSLDVARVESGFNPYAIAEIIPKR
                     ERQPGDKGFISHMPKTKEDALSIVKQIEAKGRRYSVGLMQITSTNFNSYAVTAADLFNP
                     CTNLSVFEKIITDCYQRGGTLKRALSCYYSGNFTTGQQPEAALSRTSYIQRIGYSPEKP
                     RYVVPGTRDDIATQSAILNATPVEAPARPRVVWPGAIVRGVPAQLRQKKADTVYYPAQV
                     IRGNRFSTEKED"
                     /name="lytic transglycosylase domain-containing protein"
     gene            8032..8328
                     /locus_tag="IQS16_RS23325"
                     /old_locus_tag="IQS16_23315"
     CDS             8032..8328
                     /locus_tag="IQS16_RS23325"
                     /old_locus_tag="IQS16_23315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_044862966.1"
                     /translation="MFNKLKAICSRASAYILTPLVSVVSPVFAADGFSRANTIMEKVSN
                     GLHGLAAVTITVAVIWIGYKTLWKGESLSQCGYIIIGGILIGGGSEIGALLMS"
                     /name="TrbC/VirB2 family protein"
     gene            8341..11085
                     /locus_tag="IQS16_RS23330"
                     /old_locus_tag="IQS16_23320"
     CDS             8341..11085
                     /locus_tag="IQS16_RS23330"
                     /old_locus_tag="IQS16_23320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB3 family type IV secretion system protein"
                     /protein_id="WP_137536720.1"
                     /translation="MAKLLKAMKRPAALWGVPMVPLLTVVGVTIIVAIWTSIALLLLLP
                     IEFLVMKSLTRNEPLRFNLIAVWLRVRGNPVANRLFGATAFMPVEHNAVDIQEFIDAMK
                     LNQCATIKKYIPYSSHIHPNVVRSLNSDFFCTWELTGTPFDCESDETLQFGTNQLHGLI
                     RSFEGFPVTFYVHNSREQFTDSLHKVSGNPYADTVSERYYASLNKRPFRRNRLFVTICY
                     RPFASLDKANRKRMKDGQKLKEIDSALLEVLEIKSTLDTALSRYGAHALGTFTENEAVF
                     SSQLAFYEYLLTHQWRKVRVTRTPAYNVMGNVALYFSAESGQINHVNGTQYFRGLEVKE
                     FSEETATGMTDSLLYAPCDYVITQSYTCMSREEAKKAIKRTRRLMMSADDDAVSQRLDL
                     DVALDLLTSGKIAYGKHHLSIMVFSPSLESLIADTNEISNALNNIGITPVPAEISLSAA
                     YMAQLPGNYNLRPRAGELSSLNFVELASLHNFYPGKRDKAPWGDAMALVRTPSGDGYYL
                     NLHNTLADKDEFNEKNPASTCILGTNGSGKTMLMTFLQINQQKYNRDDSFSPDARTKRL
                     TTVYLDKDRGAEINIRALGGKYYRVFSGEPTGWNPFALPATKRNINFIKQLMKILCTRN
                     GATITPRDERRLNDAVNAVMSDEPQYRVYGITRMLENLPEPATREAQENGLSIRLSQWA
                     RGGEFGWVFDNEHDTFDISNCDNFGIDGTEFLDDPNVCAPISFYLLYRITSLLDGRRLV
                     IFMDEFWKWLRDPVFKDFAYNKLKTIRKLNGMLVVGTQSPAEIIKDEIAPAVIEQCGTQ
                     ILAANPSADRSHYVDGMKFEPEVFDVIKGLDPQARQYVVVKNQFRRGDTKRFAARITLD
                     LSGIGRYTKVMSGDAPNLEIFESLYQEGMKPSDWLDSYLAKAL"
                     /name="VirB3 family type IV secretion system protein"
     gene            11100..11804
                     /locus_tag="IQS16_RS23335"
                     /old_locus_tag="IQS16_23325"
     CDS             11100..11804
                     /locus_tag="IQS16_RS23335"
                     /old_locus_tag="IQS16_23325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_032173316.1"
                     /translation="MKRFRPLILAVLIASPIVNAAGIPVFDATARLENIRQWTKEANQW
                     LQTVQHYKDQLQAYQKQLETVTGIRDIQAFVNQAKSLKADLDKLRKPGQALNDLLLSGG
                     SSGQFDELYNKYKIFDNCNAEQSKSYANTCRQEVINKAIQIEQTNEVQTQIGEMLGEIN
                     ELSDRVANAKDMKEAQDLANSIQLKSVMLNTLTTQWEMNVKAAEKREKMLAEERRKKWN
                     QQQLNAPEIMFN"
                     /name="type IV secretion system protein"
     gene            11816..12043
                     /locus_tag="IQS16_RS23340"
                     /old_locus_tag="IQS16_23330"
     CDS             11816..12043
                     /locus_tag="IQS16_RS23340"
                     /old_locus_tag="IQS16_23330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="WP_096950015.1"
                     /translation="MKKIILFTFISGLMALTSGCKEEAKTTKWYREHPDELKVVYAECQ
                     KTGSASENCKHANEAHWQIQQLNAPEISFN"
                     /name="EexN family lipoprotein"
     gene            12053..13123
                     /locus_tag="IQS16_RS23345"
                     /old_locus_tag="IQS16_23335"
     CDS             12053..13123
                     /locus_tag="IQS16_RS23345"
                     /old_locus_tag="IQS16_23335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_024187435.1"
                     /translation="MMAGIFSSVEKNIIGGITDATNGLMMSYSSMMMGLAATSATIYIM
                     WRGYQTLAGKLSTPMEDVMWDIMRMAIILSFVANINGYLDGVIDAVNGIKEGFSSSTSI
                     WQLLDTLWNSARVLGKTLHDLDNSEFIKEEGTIAELFVWGGVFVLMIITAFVSMIAEIM
                     ILLLGITAPIFIFCLMYGFLRPMFNNWLQNIFAAILTIMFSALALRIVIGFLTSRMSEA
                     VTQASKANIVELGAQVCLAGVCAAILVYMSAKLAGALAGASATATMQGAAALGIGAAAY
                     GAGKMLKEAGKVLPKEVASPSNKGLGDPQSRIVFNAADARKHAIEQMIARNEARMLTDQ
                     SAPKLPPSIKRLPPPR"
                     /name="type IV secretion system protein"
     gene            13172..13315
                     /locus_tag="IQS16_RS23350"
                     /old_locus_tag="IQS16_23340"
     CDS             13172..13315
                     /locus_tag="IQS16_RS23350"
                     /old_locus_tag="IQS16_23340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016157224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000825481.1"
                     /translation="MKRLIALALLCVLSGCAQKSKSLPPAFSGQGSPVNTPQIIAELTT
                     HD"
                     /name="hypothetical protein"
     gene            13308..13991
                     /locus_tag="IQS16_RS23355"
                     /old_locus_tag="IQS16_23345"
     CDS             13308..13991
                     /locus_tag="IQS16_RS23355"
                     /old_locus_tag="IQS16_23345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000139289.1"
                     /translation="MTEQKLIADSRSFEQQMIDRDKRATKAGFLVGGAGLLIAILSLIA
                     IVIMLPLKQTTVELYTVDNHTGRVEHVTRASKTALTAEEAYQKAMAANYVKLRERYVYP
                     ALQDDYETVQIYNSPQVNDDYLALYAGKNAPDKVYNNAAHTVKIEIISEQITNATAPDK
                     VATVRYKKIIRRMADNSIRNEYWDARFTFHSDPEKEMSDVEREINPFGFTVTSWQTDRE
                     IRGGE"
                     /name="type IV secretion system protein"
     gene            13991..14896
                     /gene="virB9"
                     /locus_tag="IQS16_RS23360"
                     /old_locus_tag="IQS16_23350"
     CDS             13991..14896
                     /gene="virB9"
                     /locus_tag="IQS16_RS23360"
                     /old_locus_tag="IQS16_23350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein VirB9"
                     /protein_id="WP_044862969.1"
                     /translation="MKKLTLITLIIMLNSQAWAAATPQASRYDARIQQVIYNPQNVTVV
                     NTKPGFMTTLVFDNDEAVISASPGFDEAWEARADANRVNIRPVALTQGAPGEDGNTTQV
                     VIPPNSRDWHTNMLIVTNKRLYNVELNVIDEKSPQQPAYLVSYRYPGDERNRANKEAAA
                     RQKEWEQKQEQAQIQKALRTAQTPRNWDYTKYPGKDSYSIEPDFAYDDGRFTFIGFSPN
                     KSVPSVTKEQNGQEYVVNSSIQRKGNFTVLVIQEITPRLVLRSGDAVVGLKNNGFGKVH
                     ATDNSTVSDKVERVEKTDNT"
                     /name="virB9"
     gene            14938..16188
                     /gene="virB10"
                     /locus_tag="IQS16_RS23365"
                     /old_locus_tag="IQS16_23355"
     CDS             14938..16188
                     /gene="virB10"
                     /locus_tag="IQS16_RS23365"
                     /old_locus_tag="IQS16_23355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000129038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB10/TraB/TrbI family type IV secretion system
                     protein"
                     /protein_id="WP_044862970.1"
                     /translation="MTDENKSPSTEEEKPVTTPDQDDIATLEREARAKREAELQASQDD
                     EQENSLQPAVNKLKKRQKGKATAFLAICAVALIGLTWGGNWVYQNFLKQEDGEKTKEVT
                     PPKKTNDYRKRTDLGMATNESENSTDGEQIVGQDNTGNVSGTAGQMKTFEPPQLNKASF
                     LVRRNNTASPQNQVKTRQQEMILAAENNATQPTDSTATTTQHGTASQAISPATVRRIPY
                     NPDLYIPENTVIPCSMDYRFVSDRAGRIRCTVAKDIWSASGNTKLIEKGTTATGIYQTG
                     ITQGQGRAFIMMTKLRTRQRPYLDIPLIDTNAAGELGESGVDGWIDTHFWERFGGALMV
                     GMIPDIGAWASNNAGKKDRNTDYTENSRQAMADMARTTLENSINIPPTLYKNQGEIINL
                     ITGQDIDFSNIYTLRMK"
                     /name="virB10"
     gene            16192..17217
                     /gene="virB11"
                     /locus_tag="IQS16_RS23370"
                     /old_locus_tag="IQS16_23360"
     CDS             16192..17217
                     /gene="virB11"
                     /locus_tag="IQS16_RS23370"
                     /old_locus_tag="IQS16_23360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125556.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_044862971.1"
                     /translation="MTVKNISLDRYKQRFFSEYLELPGLTEIAVNRPGELWTKIDGVWG
                     QHTVDLKFDDCYNFARCLAKHHNDNIEDIKPGLSATLESGERCQVVVPPACERDTISIT
                     IRKPSKIQIPHQAYIDSGFYNRVTGIEKASTHNEELIELYKSKNIPLFMEKCVEYGKTL
                     AVAGETSTGKTTYMKMLIQYIPVHLRITTIEDNPEIIFYKHKNYVHLFYPSESSDEKGS
                     VVTPAALIRWNYRMNPDRILLTEVRGGEAWDFLKITGSGHEGSMTSIHAGSAHEAIDGF
                     ITRCTENPQCAQLPYSFLLRKVLDSLDVVVSIDLDGNIRRMNDIYFRPLHRNQYYEEMK
                     V"
                     /name="virB11"
     gene            17214..17612
                     /locus_tag="IQS16_RS23375"
                     /old_locus_tag="IQS16_23365"
     CDS             17214..17612
                     /locus_tag="IQS16_RS23375"
                     /old_locus_tag="IQS16_23365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="WP_096950014.1"
                     /translation="MIKHILVTVLVTLITGCSSPPPPVPVEWNKKPVSLNDKLPEWKPN
                     SLIIKSPVINDKWTLSIRSQDFNKEDWMPSVFYAIAHSTQITVATKSGADYFSAKNWLY
                     HHGANGVIIYHPITNCLTCNETTIYFSR"
                     /name="cag pathogenicity island Cag12 family protein"
     gene            17642..17941
                     /locus_tag="IQS16_RS23380"
                     /old_locus_tag="IQS16_23370"
     CDS             17642..17941
                     /locus_tag="IQS16_RS23380"
                     /old_locus_tag="IQS16_23370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_044862972.1"
                     /translation="MKKIAAITMFVLTTATPVYSYAADPCEVVLCMYGKATGNSGGGEC
                     RSAEKAFFNIIKKKKGSIRWSKTFDARKAFLNQCSSADPAAISKIMSKFGRVRG"
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            17944..18159
                     /locus_tag="IQS16_RS23385"
                     /old_locus_tag="IQS16_23375"
     CDS             17944..18159
                     /locus_tag="IQS16_RS23385"
                     /old_locus_tag="IQS16_23375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_044862973.1"
                     /translation="MNTDENMVFYLTNSDLVYSYAHKIVHSIPSGMKGKFITSIGETIE
                     DLKRRHPDIILITESEALALQSERKN"
                     /name="hypothetical protein"
     gene            18187..18492
                     /locus_tag="IQS16_RS23390"
                     /old_locus_tag="IQS16_23380"
     CDS             18187..18492
                     /locus_tag="IQS16_RS23390"
                     /old_locus_tag="IQS16_23380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_044862974.1"
                     /translation="MLKEDMFINNIHSRNQDRIHVKRVFDDISNKANRGCGLYYEIYQA
                     KLMRGLIEHTVKLKSSDANKLISYAASQGYEITEDRYNAAIKAEDECLTEITRAQV"
                     /name="hypothetical protein"
     gene            19302..21029
                     /locus_tag="IQS16_RS23395"
                     /old_locus_tag="IQS16_23385"
     CDS             19302..21029
                     /locus_tag="IQS16_RS23395"
                     /old_locus_tag="IQS16_23385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615560.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA transfer
                     family protein"
                     /protein_id="WP_001068080.1"
                     /translation="MNPHLMQKLNGIADAFSIFLLWLQNSPVILSLLAGLTLPFIFNLP
                     REERKNAPFWLKSVACVSIFFFIFGTMSPLSIHGLSYLFDVLDPNTLLRIPLWIITILF
                     TLAGLAFHLTARRLLAGEIDSLKHRMIKKSKLERNTRTDVRKVKELLPDSIEYNPLDYI
                     DLKKGVFIGLDKDDQPQYITIKEFQKQHAAIIGTTGSGKGITASVLLYQAILLGEAVFV
                     EDPKDDEWAVHVLREACKKAGKKFVVINLNRTNHQLDLLADISHEQLEELFNAGFSLSK
                     KGEAADFYRIADRRAARNVAAIHKTGMTLYDLFNDDNVKSIGEDAPAFLGELEEIALVN
                     SVNAKNGFSLKEIFDNGGCCYIIGSTRNQKIISAQRMILTRLIQIAETRDRINTTPRVV
                     AIFLDELKYHISRPTMEGLGTARDKSVHIFMAFQAIDDLRDCPSDLNGDSVIGAVIENA
                     KFKLIYKIQNPETAEWAAKMTGSILVDDEMRKVRTDLSLTEKVDTDRMIRQAESYYVDS
                     NMFLNLPERVGFVFTSKDLPKATKMSHIPANKETIELLSFETEQIEQHNNNDVPSSGL"
                     /name="type IV secretory system conjugative DNA transfer
                     family protein"
     gene            21039..21773
                     /gene="mobC"
                     /locus_tag="IQS16_RS23400"
                     /old_locus_tag="IQS16_23390"
     CDS             21039..21773
                     /gene="mobC"
                     /locus_tag="IQS16_RS23400"
                     /old_locus_tag="IQS16_23390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000905147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_044862975.1"
                     /translation="MLIHDFYERKRISANNMLCLLNFLKDETYSDFHIIKRKLGFTKKS
                     RNPVYKLLNKALKEGFIIKHEIPSSKRKLTVWGITMQGLAMVVKADDITFPSYFEPSKL
                     KYWTLEHRLLNQRVRISLESKGATEWINGDSAAFIARYSGCSHRPDGVIKQPTGAIMAI
                     ETERTMKTRARYISIINSHLTARDKGNWHYALYVMPDTKSKESLIRLFDSIKTVMRNNT
                     PVPFDEKNREMFIFRTIDELEQ"
                     /name="mobC"
     gene            21777..22256
                     /locus_tag="IQS16_RS23405"
                     /old_locus_tag="IQS16_23395"
     CDS             21777..22256
                     /locus_tag="IQS16_RS23405"
                     /old_locus_tag="IQS16_23395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="WP_096950013.1"
                     /translation="MKILIIFALYILSPSLYANAADIQGKVIRVLDGDTIEILQNKTPV
                     RIRLANIDAPEKKQAYGRWSTDQLKSLIAGQSVRVTYSHNDRYGRIIGRVFTTGGSEAN
                     RFMVQSGAAWVYEHYNTDNALADLQQEARSQKRGLWADPNPVPPWEWRHKYKVTK"
                     /name="thermonuclease family protein"
     gene            22253..22624
                     /locus_tag="IQS16_RS23410"
                     /old_locus_tag="IQS16_23400"
     CDS             22253..22624
                     /locus_tag="IQS16_RS23410"
                     /old_locus_tag="IQS16_23400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_096950012.1"
                     /translation="MNDCFGCMHPYPAGHWFYSLQDLLTPLLENPLFYVFSFFFAGMIG
                     AIISRITKLIKTMKHGNNKKISIDNYDQIEIERYMTNEEVGRLVINFMKRTNGEPLLIV
                     FPEYDNGDDNDDKNTRCVK"
                     /name="hypothetical protein"
     gene            22593..22856
                     /locus_tag="IQS16_RS23415"
                     /old_locus_tag="IQS16_23405"
     CDS             22593..22856
                     /locus_tag="IQS16_RS23415"
                     /old_locus_tag="IQS16_23405"
                     /inference="COORDINATES: protein motif:HMM:NF022090.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilI type IV pilus biogenesis protein"
                     /protein_id="WP_096950011.1"
                     /translation="MTIKILVVSNDGHEKLIDLSPVNDLAKITKSLRTSENRMVCVIQD
                     NNRILRWDRNYASRAKNHWRKVAPDRFEILGTVEHIHYVGKC"
                     /name="PilI type IV pilus biogenesis protein"
     gene            complement(22888..23121)
                     /locus_tag="IQS16_RS23420"
                     /old_locus_tag="IQS16_23410"
     CDS             complement(22888..23121)
                     /locus_tag="IQS16_RS23420"
                     /old_locus_tag="IQS16_23410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011998900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_044862978.1"
                     /translation="MANVPPKPRNNKGEPPSLEDTQHGFNPTRKNADGRKAQLNLYVDM
                     EVKREFRSIAAANDMKHGELLEAYQEFWKKHH"
                     /name="hypothetical protein"
     gene            complement(23161..23808)
                     /locus_tag="IQS16_RS23425"
                     /old_locus_tag="IQS16_23415"
     CDS             complement(23161..23808)
                     /locus_tag="IQS16_RS23425"
                     /old_locus_tag="IQS16_23415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214917.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_000214917.1"
                     /translation="MTVAIALVNGKGGVKKSSMSRAIATEYTKADWKVLGLDMDVDQGS
                     FLDWGQRRLRYKVEPPVTIQGCGTVSQAKKHIESGIWDLVVIDSAAYATKSLLSLAEIV
                     DLLVLPSGFSVDDLRTTVTTVNALRNKGHSTNKMAVVFVGVSESESEYRTALEYLKPCG
                     VQVINGAIPFMTSFSQAQDKGLALTESPFPGPRQKADEVVQGVIDLLTKLSQ"
                     /name="ParA family protein"
     Typing          21040..21770
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="98.77"
                     /coverage="100.0"
                     /evalue="1.66e-162"
     Typing          8342..11082
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="87.637"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          13309..13988
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="85.903"
                     /coverage="100.0"
                     /evalue="3.85e-119"
ORIGIN
        1 aaatagtccc gtttcccttg aaattataag ctgtagctta tacaatcatc tataagctat
       61 aacttatagg aaaagggaca tgtggactgt ttattttggc agattatttg atgaatggtt
      121 tgaagagcag gaactagccc taaaacgaaa agtgctggct gaacttaaac atcttgaaga
      181 gtttggcccc tctctttcac ggccacatgc agatacagtg aaagggtcac gtcataagaa
      241 tatgaaggaa ctacgtatac aatatgaggg acacccaatc agggcattct ttgcatttga
      301 tccaattaga caagcaatca ttctttgcgc tggcgacaaa agtaatgata agaaatttta
      361 cgacagaatg attcgtattg ctgacgaaga attttccact cacttagccg aactggaggg
      421 caaaaaatga gaacattaga agaagtaatt gcggctcaat cacctgaaag tcaggcgatc
      481 atcaaagcta tggctgatga gatgattctg gaaacagggc tgcaaatgat gcgtgaagaa
      541 ttgcagcttt cacaaaaaca ggttgctgat gcaatgggaa tcagtcagcc cgctgtaact
      601 caactggaac agcgcggaaa tgatttgaag ctggcaacgt taaagcgtta cgttgaagct
      661 atgggaggaa agttgagcct agatgttgaa ctccctaccg gaaagcgagt ggcctttaac
      721 atttagtaga aaaggggcga aaagcccctt ttggggtcag acagtggttg gttctgcggt
      781 gatcgtatcc cttttacaaa gaacatattc agggtgtttt ccagccaaca acaataagta
      841 gttatattca cctacagata aagaccttgt agctttacct gcgctttctt tcatttgcca
      901 agtatttaac tgatagccaa aaatttcggc agcttcctta agcgttaaac ctgcggaaat
      961 tctcgcctct ttaacatctg ccggagttgg tttagtttgc attgttatta cctcttttaa
     1021 ataaatcagc cagaatacca ttatcaagat ccaataattc tggcaatgta agattcgtat
     1081 cgagcaccaa ttttttaact gtctttttcc ctttaacttg ctctttatca caagatttca
     1141 catatgtctt aacatacttt ctgaccatat acatctgatt atccatatct actgtaacaa
     1201 cataagagta actaccctta cttttaaaga aaacattatc agttttcata aacaacccca
     1261 tataaaattc acatcaacac tttgttatag tttttttata aaaccagcca ctttgataag
     1321 ttgatcaaca ttaagccctc tgataaccat ttcataatca tcaccatttt gtagtatttt
     1381 tcctgtaagc ccattatcca cattaaatcc cgttaatgcc ccataccaag gggatataga
     1441 aatcaactgt gataacatcc ctttgattat ttgtacttta tcttgttttt tctgtaatgc
     1501 gttctcatgc ttcccgagca attcaatttc atctagtgca ttagctagga ttttccgaga
     1561 tatatcatta gcaataccaa caggattgcg tgtaagagat accgtacaga cggaaggatt
     1621 accgtgccat acaagactat caacactacc aacgataaaa aatctttcac gctccagacg
     1681 aataatgatg gagtatttac gaagttctgt agaagtcagt ttaatacgat gctgataatt
     1741 atccagttta ttaacacgcc aaccgttccc cagaatacgg catacaactt caaagactgg
     1801 ctgatatttt tctgaaaatg ttgtcatgtt ttcacatcct ttactgcgct aacatagcca
     1861 gcaattgcag agtatcagct actcaatcct tttcgggttc gatgcccgaa aaggattgct
     1921 ggcgaggata cagggggctt acgcccccgt ttcgttatgc tctggcttca actcttgccc
     1981 tgccttcaac ttgttgccat cctccggcct ggaattttcc gcttgtgcca tattttgcgc
     2041 ggatttcctc tatcgtgtgc tcttcacggt tccagtaact tttatgttct tctggacgat
     2101 aaaaccattg ttttttcttt gccgcccatt tacaccctat ttcttttaat gcttctttgt
     2161 gctcgatagt atttccacta atccaaatcc agttaccaat aacctcataa actaaaccag
     2221 acaaaccgta aagagccttt aaaacatttt ctagttcatc accatagtta tatattgcac
     2281 tttgttcagg actttggtat tgattaatct tatcaagatt cgccattaaa aaatcgaatg
     2341 ctaaattaac cgccttcatc atttcggcac ctaccggatt gcggtcagga tgatatttta
     2401 atgcagcttt tttaaaggcg tttttgatgt ctttttcagt caactgacca gacaagccaa
     2461 aaatatttaa tgcttcttgg atattcattt tgtagctccc gcccctgtgg ggctaagatg
     2521 agagggaaac catttccctc tcgatgattt aattatacct tcaactgcag gtattgcaag
     2581 ttttttagct ctattttgaa aaaattataa ttactgtcag gacatcaaca ttatttaaaa
     2641 catttcatat ccctgtaaat aatttaacca ccacctgaat tgatcccaat ccgtaaattt
     2701 cattgctggg attctcgttt cccatccttt gacaagtgaa tccgcaagtt gtacgatctg
     2761 gcctgttgac atttgaacac ctctctattg ttttgagtgt cgataaagtg atcaggttgc
     2821 tcgaccaacc tgatcactcc tttatagaat atatggctat tgcatacatt ctatatattc
     2881 tttaagattc aaagactcct cacctatttt taaattatca aaatactttt catatttttt
     2941 agcataatac tcaatcagtt caatatcttc ttgcataatt tcccctaact cttctattac
     3001 accattttta taatctcgaa tcttattgtt atcggtaaat actacaacat attttttacc
     3061 agtctctata tgaattaatc caatagtaca aagtgtcaaa gtattaaaaa taaaaatctg
     3121 ttgcgtggtt gattcaatat aaggtaagcg agccattttt aaattccacc tgctttagat
     3181 ttggagtaaa taaagagcca tataacgggg caattgcccc gttgaggact tacagcaacg
     3241 ttttgtaatg ggctaaaagc gcttccagtt cagtcgcttt ctttctgaaa acagggggat
     3301 gggactctac cgcatcaatc agtgcgtcaa gttctgttgt gatttcctgc aaagtactta
     3361 aaaattctgt accctcctgg ctggtcatcc aggaaacaaa ggcttttact gcctgttcct
     3421 gcataacttc aatttgggta atagcgtctt tttgctgatc accagttgct ttaaatgtgg
     3481 ttctaaaaat aaatgcactc attttaatct cccgcccctg tggggctaag tggaaaggga
     3541 accatttccc tttcgatgat tttattatac ctgcatacgc aggtattgca actatttttc
     3601 actatttgaa ctgaaaaatt ttccaccact cacctttaat tccttcgcgt atgtgctcaa
     3661 ttcagcaagg gcactattcc gcttcctcac ccactcgctc actaacgttc ggtcgctagg
     3721 gttgcggcga gcggatctac ttccctaggg ttgtacaccg gaaacgccga aatttccgat
     3781 ttccaaactg acccccaaca ggaacctttt tgtgattttt cgcgatcata ttgttagcag
     3841 ttagttaagt tatgctcgat ggtgggaaga tgccgcgtta gcggcatgta aggcgcgaaa
     3901 tacagtttca tagaatcaca aatgccaggg cgcgccgata cccctaacca agggctttca
     3961 ggtcactagg aaccgcgtca gccccctgct aagccaaaat tgcacgggac ttacagctat
     4021 tcaggtggta ggtggtcgta gaccgtcgat gttacagcga tgataggtga gtgattgttc
     4081 gttcttgatg attggatacg gtgctttcaa tgccccgacg cttgcgaggg gtgctacctt
     4141 tgaggcgctt gcgccgatgt ttttcagtta tccacttgtt aaaggggata acagtaatgt
     4201 ttttcttttt tgcttctctt ttagtacgta agtaactaaa agagaagcaa aagagtaatt
     4261 gcggcatatc gtttgcactt tatttatgat tatccacaac ctgtacatcg tttaccctct
     4321 ggccataacc tatggctgct ctttcctgag catgggaaac ggaaaacacc tcacgttgag
     4381 actgtttttt gtacagagtt ttattacgga cgtgacgata taccgcccat aaggcggtaa
     4441 gttagccagc atcaggccgg aataggggta ggtggatctg cgtaatattc ttttttgcgt
     4501 tgtcgagctg cgtcgcgttt tgctttcatc ctggctaatc cggctgccgc tttccgcgtc
     4561 cagttctgga ctctgatagc tataagtctg gcatcaccgg agtaaatcac ttcatcagga
     4621 tctgccttta acagcctggc tcgttcccga taaaccagtt ttaacggaat gccaaggatg
     4681 gcaaagaaat cctcggttac ttcaatgtgt ttacaggcac accgtgcatc atacgggtta
     4741 aacggagcct tctctgtaat gatggcattc aaccaaacca ggcgatcaca accacgactg
     4801 gcgcgagaaa tggatttatg tcccgcatcg ctgcgtgtaa ccagtccggc acgttcggca
     4861 agcgtttcaa ggttatgcct ggtttcccac gagcgtaaat cgagatcgtc cagaatagct
     4921 aacatcaatt cgcaaagagc ctctatgcca aacttgttag cctcattaac ccaatagcgg
     4981 ttatgccgga tacggcgacg gagttcgttt ttgattttga tacgccctgc gaccgtcgtc
     5041 agcgatttaa tccagcgatt gaggaaacgg cgtcgcttac gcgacacaac gttatagcat
     5101 ggactttgtt ttgccacccc tgacggcgat atgcggggga ttaaggagtt gttcttttca
     5161 gccaccaccg cccgcactta ttgccggaca gaggtcttgt attgagaaat gcatttgcta
     5221 taatcctttg caggcaccag cctgctttgg accccctgat tatcttcttg gaccggcaaa
     5281 atcgaagaga gatatcaggg ggttgttgca ttcagggggg ttaaaatgct tccccccttc
     5341 ccctggacgc tgttacggga acgtcccacc caaaaatccg taaaaaccgc acgaaaatag
     5401 catgaaccca ttcgaagatc aattcatcca caaaagatcc cgccgattac cttcctattt
     5461 ttctttaaac ttcatctggt tatataactc ttaacaaaat tgagattaaa taccgtacag
     5521 cacataactc atgatattaa tgctaatgta cgcatacatt agcattaata tcgaaaaaaa
     5581 aatcggcgac aacaaacgga aaaataaagg attttgataa aaatatgtaa gagtatttac
     5641 cgctcgccac aaccctagcg accgaacgtt agtgagcgag tgggtgagga agcggaaaag
     5701 cgacttgacc aaatggagca catacgcact gatgcctacg cactcattcc tttagatatt
     5761 catttaattg agcaactatt ttttttacgt tatccagctt agatgccatt cttcttgctt
     5821 ctacttccga atcgtaatta gggtttagct ctggactcgt acgttttcgg tgaaaatcaa
     5881 gaacagcctt tgcaaaatca tcgtcttctg tatagaaata attttcagga taatcaagaa
     5941 gttctgcgat tttttttaca agtttaaaag gtggttcagt tctgcctacc tcgtagcttg
     6001 aaaatcgaga tcgagtgtta ataccttccg ctacaccaag aagttgagat aatttttctt
     6061 gagataatcc agcctccatc ctcgcttctt tcagtcgttt aggcaccata atacaacctc
     6121 ccttttttgg gaatcccatc ttacagggcg ttacaggcct caaagtcaac ataatgaatc
     6181 agggttgatt ttgaatcgag caatgctatt atttctttag attcttgata ttgacacgca
     6241 agaatagctg tataaaatca caactgtgta tttttacagt taacacttaa tgagtacgtc
     6301 aacctaagcc cggcaactta ggacggcgga aaatgggggc ttgtgtccgt aaggtgacgc
     6361 ttatgaatgc atggtatctt ttatactgta ataacaacga cttagatcgt attgcatatc
     6421 gttgtaaaac tatgaacgtt gtagctttct gtccgagata cataaagttc acacctcgga
     6481 aagattgcaa cgcagtgcgc aaggaagaaa aagttttatt tcctaactac ctcttcctcc
     6541 attttgatgt gaatgtcaca cacacgtcag caataacctc tattccaggt gcaattggct
     6601 tcgtaagttt cggttccaca atatgtactg taccggaaaa agtcgttatc gctattaaat
     6661 gcgccaagat actggcgcta aatcctgatg atgattccat agagtgccgt aacatcggta
     6721 gtgacctact ggcagaaatt caacgcatat cttcaatcat ctcaccgtta gaacgtcaaa
     6781 cggccttctc caggctttta cagaatcagt aaaccagacc ttcattcctt ctccagccgt
     6841 accgctgtgc ttttgcacac ggatatttca tacaggagct ataaactcat gccgaaccct
     6901 ataggccagg ctaaatctac agccgttatt tacatcggca aaaaacgcta tgaaacactg
     6961 gcaaaacacg ccagagatat aagttatgtt gcggaggtaa atattcgtcc aagtgccttt
     7021 ttgcagtaca tgatcgacaa attaagtaat gaagctcaca acgaaatgtt gaaagagcta
     7081 atgtcaaaag aggataaata aatgcccaaa cccacctata acgtatacgt cacacaggaa
     7141 gttcccactg acgaaaacgg cggtaaaaat acctactgga ccaaggttgg cgcggcattc
     7201 gcgcataacg ggaaaccagg actgaatatt atgctcgttc ctggtattgc tgtttccggc
     7261 aagctggtac tactcgaacc taaagaagac gccccacaag gaaactaatt tagcgagggt
     7321 actatgcttt ccaccgtttc atttatggcg gtggctatgc agtgtgccgc cacagttcac
     7381 ccctccacat ctctggatgt tgcgcgggtc gagtctggtt ttaatcccta cgctattgct
     7441 gagatcatcc ccaaacgtga acgccagcca ggcgacaagg gctttatctc acatatgcca
     7501 aaaactaagg aggatgcatt aagcatcgtc aaacagatag aggcaaaagg tcgtcgctat
     7561 tctgttggtc tgatgcaaat cacaagtaca aattttaata gttacgccgt aacggctgct
     7621 gacctgttca acccgtgcac aaatctttct gtttttgaaa agatcatcac tgattgctac
     7681 cagcgaggcg gcacactgaa acgggcgctg agttgttatt actctggaaa ttttactaca
     7741 ggacaacaac cagaagctgc gttatccaga accagttaca tacagcgaat tggttactca
     7801 cctgaaaagc cccgctatgt cgttcctgga accagggatg atatcgcaac tcaatcggcc
     7861 attctgaatg caacacccgt tgaagctccg gcacgccctc gcgttgtctg gcctggcgca
     7921 atcgtgcgcg gggttcctgc tcaactgcgc cagaaaaagg cagataccgt ttattacccc
     7981 gcacaagtta tacgcggaaa cagattttca actgaaaaag aggattaacc gatgtttaac
     8041 aaattaaagg ccatttgcag ccgcgcatct gcttatattc tgactccgtt agtaagtgtt
     8101 gtcagtccag ttttcgcggc tgacggtttt agccgagcaa ataccatcat ggaaaaggtt
     8161 tcgaatggtc tgcatggtct ggcagccgtc accatcaccg tcgctgtgat ctggattggc
     8221 tataagactc tgtggaaagg cgaaagcctg tcgcagtgcg gttacatcat cattggcggc
     8281 attttaattg gcggaggcag tgaaattggc gctctgctaa tgagctaaga ggccgaacat
     8341 atggcaaagc tgcttaaggc gatgaaacgt ccggcggcgc tgtggggggt gccaatggtg
     8401 cccctgctga ctgtcgtggg cgtgacaatt attgttgcta tctggacttc catagcccta
     8461 cttctcctcc tccctattga gtttctggtt atgaaatcac tgaccagaaa tgaacctctg
     8521 agatttaacc tgatagctgt ctggctaagg gtaaggggta atccggtagc aaaccgttta
     8581 tttggcgcaa ccgcatttat gcctgttgaa cataatgctg ttgatatcca ggagtttatc
     8641 gatgcgatga agctaaacca atgtgccacc ataaaaaaat acattcctta ctcgtcacat
     8701 attcacccta atgttgtccg ttcactgaat agcgattttt tctgtacctg ggaactgaca
     8761 ggaacgccgt ttgattgtga atctgacgag acactacagt tcggtacaaa ccagttgcac
     8821 gggctaatac gctcatttga aggctttccg gttacatttt atgtacataa cagccgtgaa
     8881 cagtttacgg actcactgca taaggtttca ggaaatcctt acgcggatac cgtgagcgaa
     8941 cgctattacg catcactgaa taaaaggcca ttccgacgta accgcctgtt tgtgaccatc
     9001 tgctatcgtc cgtttgccag tctggataag gcaaaccgta aacgtatgaa agacggtcag
     9061 aagctaaaag agatagacag cgcattactt gaagtgctgg aaatcaaaag tacgctggat
     9121 acagccttat cccgttatgg tgctcacgcg ctcggtactt tcaccgaaaa cgaggctgta
     9181 ttctcgtccc aactggcatt ttatgaatac cttctcacgc atcaatggcg aaaagtcaga
     9241 gttacacgta cccccgctta caacgtaatg ggaaatgttg cgctgtactt ctccgccgaa
     9301 tcagggcaaa taaatcatgt taatggcacg caatatttcc gtggtctgga ggtaaaagag
     9361 ttttcggaag aaaccgcaac gggcatgaca gactccttac tgtacgcgcc gtgcgattat
     9421 gtgattacac aatcctatac ctgcatgtcc cgtgaggaag cgaaaaaggc gattaagcgc
     9481 acccgacgac tgatgatgag tgctgatgat gatgctgtat ctcaacgtct ggatctcgat
     9541 gtggcgcttg acctgctcac ctccggtaaa atcgcctacg gtaaacatca tttatcaatt
     9601 atggtgtttt cgccgtcact ggaaagcctg attgcagaca caaacgagat cagcaatgca
     9661 cttaacaata tcgggataac ccctgttcct gctgaaatct cattgtctgc ggcctatatg
     9721 gctcaattac caggcaatta caatctgcgg ccacgagctg gagagctgag tagcctgaac
     9781 tttgttgaac tggcatcact tcataatttc tatccaggaa aacgcgacaa agccccgtgg
     9841 ggtgacgcga tggcactggt gcgaaccccg tcaggtgatg gctactatct gaatctgcat
     9901 aacactctgg cagataaaga cgagttcaac gaaaaaaacc ctgcaagtac ctgcattctg
     9961 ggtacaaacg gttcaggtaa aacaatgctg atgacgtttt tacaaatcaa tcagcaaaaa
    10021 tataaccgtg atgacagctt ttcaccggat gccaggacta aacgactaac cacagtttac
    10081 ctcgataaag accgtggtgc tgaaatcaat attcgcgcac ttggaggaaa gtactacagg
    10141 gtattcagcg gtgagccaac aggctggaac ccatttgctc tgccagccac taagcgaaac
    10201 atcaatttca ttaagcaact gatgaaaatc ctttgcaccc gcaacggtgc aaccataacg
    10261 ccacgtgatg aacgtcgcct caatgatgct gtaaatgccg tcatgagtga tgagcctcaa
    10321 tatcgcgtct acggcataac ccgaatgctg gagaacctac cggaaccggc aacgcgtgaa
    10381 gcgcaagaaa acggcctgag tatccgtctt tcacagtggg cgcgcggtgg tgaatttggt
    10441 tgggtgtttg ataacgaaca cgacactttc gatatcagca actgcgataa tttcggaatt
    10501 gacggaactg aatttctgga tgacccgaat gtctgcgctc ctatctcgtt ttatctgctg
    10561 taccggataa ccagcctgct ggatggcaga cgacttgtta ttttcatgga tgaattctgg
    10621 aagtggttac gcgaccctgt atttaaagat tttgcgtata acaagctgaa aactatccga
    10681 aaactgaacg gtatgctggt tgttggcacg caatcgccag cggaaataat caaggatgag
    10741 atagctccgg cagttattga gcaatgtggt actcaaatac tggccgccaa cccaagcgca
    10801 gatcgctctc attacgtgga tggaatgaaa tttgaaccag aagtgtttga tgtcattaaa
    10861 ggacttgatc cacaggcgcg gcagtatgtc gttgtcaaaa atcagttccg ccgtggagat
    10921 acaaaacgct ttgcagcccg tatcacgctg gacctgtctg gtatcggcag atacacaaaa
    10981 gtaatgagcg gcgatgcacc caacctggaa atattcgaat cactctatca ggagggaatg
    11041 aagcccagcg actggctgga ttcctacctg gctaaagcac tataaccaag gagatatcga
    11101 tgaaaagatt tcgccccctt attctggcgg ttcttattgc cagcccgata gtaaacgctg
    11161 ctggtatacc cgtgtttgat gcaacagcca gactggagaa tattcgccag tggacaaaag
    11221 aagccaatca atggctacag acggtacaac actataaaga ccagctacag gcgtatcaaa
    11281 aacaactgga aacagttaca ggcatccgtg acattcaggc attcgttaat caggccaaaa
    11341 gccttaaagc tgacctggat aaactacgta agccagggca agccctgaac gatttgctct
    11401 tatccggcgg ttcttctggc caatttgatg aactgtacaa caaatacaag attttcgata
    11461 actgcaatgc tgaacaatca aaaagttatg ccaatacatg cagacaagag gtcatcaaca
    11521 aagcaataca aatcgaacaa accaatgaag tacaaaccca gattggtgag atgcttggtg
    11581 aaatcaacga attatcagac cgtgtagcaa atgccaaaga tatgaaagag gcccaagact
    11641 tagcaaacag tattcagtta aaatctgtga tgctaaatac gctcacgacc caatgggaaa
    11701 tgaacgtaaa agcggcagag aagcgtgaaa agatgcttgc tgaggaacgc cgtaagaaat
    11761 ggaatcagca gcaattaaac gcaccagaaa taatgtttaa ttagcaggtg acttaatgaa
    11821 gaaaatcatt ttatttacat ttatttcagg cctgatggcg ttaacttcag gatgcaagga
    11881 agaagctaaa acaacaaaat ggtatcgtga acatcctgat gaactcaaag ttgtttatgc
    11941 tgaatgccag aaaacaggca gcgcatctga aaactgcaaa catgccaatg aagctcactg
    12001 gcaaattcaa caattaaatg cacctgaaat aagtttcaac taaagggcgt ttatcatggc
    12061 cggtatattt tcttctgtcg aaaaaaatat catcggtggg ataactgacg cgactaatgg
    12121 tttgatgatg tcttattcgt caatgatgat ggggctggcg gctacgtcag ccactatcta
    12181 cattatgtgg cgaggatatc aaaccttagc ggggaagctg tctacaccaa tggaagatgt
    12241 tatgtgggat ataatgagga tggctatcat tttatccttt gtagcaaaca ttaacggata
    12301 tcttgatggt gtcattgatg ctgtaaatgg aataaaagaa ggtttttcca gtagcacaag
    12361 catctggcaa ttacttgata ctctatggaa cagcgcaaga gttttaggta aaacgttaca
    12421 tgatctagac aactccgaat ttatcaaaga ggaaggcaca attgctgaat tatttgtatg
    12481 gggtggtgtc tttgtcttaa tgattatcac agcattcgta tctatgattg cggagatcat
    12541 gatcttattg ttaggtatta ccgcaccaat atttatattt tgcctgatgt atggcttttt
    12601 acggccaatg tttaataact ggcttcaaaa tatatttgct gcaatactaa caattatgtt
    12661 ttcagcctta gctctgcgaa ttgtaattgg ttttcttaca tccagaatgt cagaagcagt
    12721 gacccaggcc agcaaagcaa acattgtaga acttggtgct caagtttgtc ttgccggagt
    12781 atgcgctgca atactggtgt acatgtccgc aaaactggct ggggcacttg caggagcaag
    12841 tgctacagcc actatgcaag gtgcggcggc tctcggcatt ggcgctgctg catacggcgc
    12901 tggaaagatg ttaaaggagg caggaaaagt attacctaaa gaagtagcaa gcccaagtaa
    12961 taaagggtta ggagatccac aatcgcgcat agtatttaac gctgctgatg cacgtaaaca
    13021 cgctatagaa caaatgatag cgcgtaatga agcgcggatg ctgacagatc aatcagcacc
    13081 aaaactaccg ccatcaatta aacgtttacc tcctccaaga taactataaa aatataatta
    13141 tatttttata gaaaaacaaa aggtacataa aatgaaacgc ttaatcgcgc tggctttgct
    13201 gtgcgtgctt tctggctgcg cacaaaaatc taaatctctg ccgcccgcat tcagcggtca
    13261 gggtagccct gtaaacacac cccaaattat cgcggagcta accacacatg actgaacaga
    13321 aattaattgc tgattcccgc tcgtttgagc agcaaatgat tgacagggat aaacgcgcca
    13381 caaaggcagg ctttctggtc ggtggagctg ggttattaat cgctatcctg tcactgatcg
    13441 cgatagtgat tatgttgcca cttaaacaaa caacagttga actctatacc gtagataatc
    13501 ataccggacg agtggaacac gttacccgtg catcaaaaac agccctgaca gcggaagaag
    13561 cctaccaaaa agctatggcc gccaattacg ttaaattacg tgaacggtac gtttatcctg
    13621 cattacagga cgattacgag acagtacaga tctacaactc accacaggta aacgacgact
    13681 acctggcact gtacgccgga aaaaacgcac cagacaaggt ttataataac gcggctcaca
    13741 ccgtgaaaat tgaaattatt tctgagcaga taacgaatgc aacagcacca gacaaagtag
    13801 ccaccgttcg ttataaaaaa ataattcgtc gcatggctga taacagtatt cgcaatgaat
    13861 actgggatgc acgtttcacc ttccattcag accctgaaaa agaaatgtca gatgttgagc
    13921 gggaaataaa cccgttcgga ttcaccgtaa caagctggca gactgaccgc gaaatcaggg
    13981 gaggcgagta atgaaaaaac tgacgttaat taccctgata ataatgctga acagccaggc
    14041 atgggccgca gctacaccac aggcgagccg ttatgatgca cgtatccagc aggtcattta
    14101 taacccgcag aatgttaccg ttgtaaacac aaaacctgga tttatgacga ctctggtttt
    14161 tgataacgat gaagctgtta tcagtgccag tcctggcttt gatgaagcat gggaagccag
    14221 agcagatgca aacagggtta acattcgtcc ggttgcgctc acacagggcg cacctggtga
    14281 agacggtaat acaacacagg ttgttatccc gccgaacagc cgtgactggc ataccaatat
    14341 gctgattgtg acaaataagc gcctgtacaa cgttgaactg aatgtcattg atgaaaaatc
    14401 gccacaacag cccgcatacc tagtgagtta ccgctatcca ggggacgaac gtaacagagc
    14461 caataaggaa gcagcagcac gtcagaaaga atgggaacaa aagcaggaac aagcccagat
    14521 tcagaaagca ctgagaaccg cacaaacccc gcgtaactgg gactacacga aatatccagg
    14581 aaaagacagt tacagcattg aacctgattt tgcctacgac gacggtcgct ttacgtttat
    14641 cggattctca cccaacaaat cagttccatc agttaccaaa gaacagaacg gccaagaata
    14701 cgtggttaac agcagtatac agcgtaaggg caattttacc gttctcgtta tccaggaaat
    14761 cacaccacgg cttgtactac gttcgggtga tgccgtagtg gggctgaaaa ataacggctt
    14821 tggaaaagta cacgcgactg ataattcaac cgtatctgac aaggtggagc gcgttgaaaa
    14881 aacagacaac acctaatcta taaaaatata attatatttt tatataagga ctcatatatg
    14941 actgacgaaa ataaatcccc ctctacggaa gaagaaaagc cagtgacgac acctgatcag
    15001 gatgatatcg ctacgctgga acgagaagcc agagcaaaac gtgaggctga attacaagca
    15061 tcacaggacg atgaacagga gaactcatta caaccagcag taaacaaact gaaaaaacgt
    15121 cagaagggga aagcaacggc ctttctggca atttgcgcag tagccctgat tggcctgaca
    15181 tggggcggta actgggtata tcaaaacttc ctgaagcaag aagatggaga gaaaacaaag
    15241 gaggttacgc cacctaaaaa aacgaatgac taccggaaac gaaccgattt aggaatggcc
    15301 accaatgagt cggaaaattc gactgatggt gagcaaattg ttggccagga taacacgggc
    15361 aatgtatccg gtactgccgg acagatgaaa acatttgagc caccacaact gaataaggcc
    15421 agtttccttg ttcgtcgtaa taatacggcc agcccccaaa atcaggtcaa aacaagacaa
    15481 caggaaatga tactggctgc ggaaaacaac gccacacagc ctacagacag tacagcaacc
    15541 acaacacaac atggcactgc atcacaggca atttcccccg cgacagtgcg aagaatcccc
    15601 tacaaccctg atttgtatat accggaaaac acagtcattc catgctctat ggattaccgc
    15661 tttgtttccg atcgcgctgg aagaatacga tgtacggtag ctaaagatat ctggagtgcc
    15721 agcggcaata caaaacttat cgagaaggga accacggcaa caggaatata ccagacggga
    15781 attacgcaag ggcaagggcg cgcttttatc atgatgacaa aattacgtac ccgacaacga
    15841 ccatatctgg atattccgct gattgatacc aacgccgctg gcgagcttgg agaatcaggt
    15901 gttgatggat ggattgatac acacttctgg gagaggtttg gcggcgcatt aatggtcggc
    15961 atgatcccag atattggcgc atgggcatca aacaatgcgg gtaaaaaaga ccgcaataca
    16021 gactatacag agaacagccg ccaggctatg gcggatatgg ctcgaaccac gctggaaaac
    16081 agcattaata ttccaccaac gctttacaag aatcagggag aaataatcaa cctaattaca
    16141 gggcaggata ttgacttctc aaatatctac acgctgagga tgaaatagaa catgacggtt
    16201 aaaaacatat ctcttgatcg ctataaacaa cgttttttta gtgaatacct ggaattacca
    16261 ggactgacag aaatagctgt taatcgtcca ggtgaactct ggacaaagat agatggcgtc
    16321 tgggggcaac ataccgttga tctgaaattt gacgattgct ataactttgc acggtgtctt
    16381 gcaaaacacc ataacgataa tatcgaggat atcaaaccag gactttctgc aacccttgaa
    16441 tcaggagaac gatgtcaggt tgtcgttcct ccggcgtgcg aacgtgacac gatctcaatc
    16501 acgatccgta aaccgtcaaa aattcaaatt ccgcatcagg catatattga tagcggtttt
    16561 tataaccgcg tcacgggcat tgaaaaagca tccacacata acgaagaact gattgaatta
    16621 tacaaatcaa aaaacattcc tttgtttatg gaaaaatgcg tggagtatgg aaaaacattg
    16681 gccgtcgcag gtgaaaccag tacgggtaaa acaacataca tgaaaatgtt gatacaatat
    16741 atacctgtcc atttacgcat aacgacgata gaagacaacc cagagataat attctacaaa
    16801 cataagaact atgttcatct gttttatcct tctgagtcat ccgatgaaaa aggatctgtt
    16861 gtaacaccag cggcgcttat acgctggaat taccggatga atccagacag aattttatta
    16921 acagaagtga ggggtggaga ggcatgggat tttctgaaaa taacggggtc aggccatgaa
    16981 ggaagtatga cctccattca tgctggttca gcacatgaag caatcgacgg ttttattacc
    17041 cgctgtaccg aaaacccaca gtgtgcgcaa ttaccatatt cattcttgct acgtaaagtt
    17101 ctcgactctc tggatgttgt tgtgagcatt gatttagatg gaaacatacg ccgtatgaat
    17161 gatatttatt tccgaccgtt acaccgcaat caatattacg aggaaatgaa agtatgataa
    17221 agcatatact ggttactgtg cttgtaacac taattaccgg atgttcctca ccgcctccac
    17281 cagtacccgt ggaatggaat aaaaagccgg tatcgcttaa cgataaactt cctgaatgga
    17341 aacccaatag cttaataata aaatctcctg ttattaatga taaatggacg ttatccatta
    17401 gatcacaaga tttcaataaa gaagattgga tgccatctgt cttttatgcc attgctcact
    17461 caacacaaat cacagtagca acaaagtcag gcgctgatta tttcagcgca aaaaactggt
    17521 tgtatcatca tggtgcaaac ggggtaatta tatatcaccc catcacaaat tgtcttacgt
    17581 gcaatgaaac aaccatctac ttttcgcgtt aacacaaata tattaaacca agggttctga
    17641 catgaaaaaa attgcagcaa taacaatgtt tgttttaaca accgccacac ctgtttactc
    17701 ttatgccgca gacccatgcg aggttgtttt atgtatgtac ggaaaagcta caggaaacag
    17761 cggaggtggc gaatgcagat cagcagaaaa agcattcttc aatattatta agaaaaagaa
    17821 aggttcaata cgatggagta aaacatttga tgcacgtaaa gcatttttaa atcagtgttc
    17881 atcagctgat cccgcagcca tatctaaaat aatgagtaag tttggtagag tccgaggtta
    17941 aatatgaata cagatgaaaa catggtattt tatctgacaa actccgatct tgtttatagc
    18001 tatgcacaca agatagtaca ctccattcca tcaggaatga aaggaaaatt catcacttct
    18061 attggtgaaa ctattgaaga tttaaagaga cgacatcctg atattattct cattacagaa
    18121 tctgaagcat tagcattgca atcggagagg aaaaattaac atattctttc agatctggag
    18181 aatcctatgt taaaagaaga tatgttcatt aataatattc attcaaggaa tcaggacaga
    18241 atccatgtaa aaagagtctt tgatgatatt agtaataaag caaacagggg atgcggacta
    18301 tattatgaaa tatatcaagc gaagttaatg cgagggttaa ttgagcacac agtaaaactg
    18361 aaaagttctg atgccaataa gctgattagt tacgctgctt cacaaggtta tgaaataaca
    18421 gaagatagat ataatgctgc aataaaagcc gaggatgaat gtctgactga aataacacgg
    18481 gcacaagtct gaggcagagg attgcgtagc aacccgaagg gcggggcaaa ttcgctttgc
    18541 gaatttgggc gagtccgacg cagggcgtgg tgcagttcag gctttcttta tttctggctt
    18601 caatttcgaa gaaattgtta agacaggaat aaagaaagtg gtgcgtggac agaaaattca
    18661 atttcgaaga aattgttaat tttcaggcac cacgcccacc cgcgaacatt cgccccaagc
    18721 gaattgaagc gggccggggg gagccgcaaa aatttttccg ccccagcgag aaaaaaggca
    18781 cgcccacgtg ccggtttttg tggggggctt gccccgcaca ccgtcgggcc aggtaatatt
    18841 tcccgcccca gcgggggata ttaccgatta ggcgcgacca ccccctttaa agcagcgttc
    18901 caattttttc gagcttgcga agaaaaaata ggctaaacgc gcgtcttaaa gggggtggtc
    18961 gcgcgtagcg cgcgacggtg tgccgccttt gaccttgggg gttttggtcc ggcgtccaga
    19021 cgggccatta cccccatgtg acgtgaagga ctggcgttcc agccaggccg aaacggcaca
    19081 cgccgttgcc cgttattcgg gctttcagga gccagacgat aacttatcgg ctggattctg
    19141 aaagaacgga taacgggcat gatcgcctaa ggcgatcaca atgtttttgg cttttattgg
    19201 ggtacaacaa tggggtacag ctatggggta catcatatcc cccattactg taccccattg
    19261 ttgtacccca tagattcact ttaataatgg ggaaaacaaa tatgaatcca catctaatgc
    19321 aaaagctgaa tggtattgct gatgcctttt caatatttct gttatggcta cagaacagcc
    19381 cagtcatatt gtcattactg gcaggactaa cactaccatt tatatttaac ctaccacgag
    19441 aggaaagaaa aaacgctccc ttctggttaa aatctgttgc gtgcgtgtcc attttctttt
    19501 tcatattcgg cacaatgtca ccacttagta ttcatggtct gagctaccta tttgacgttc
    19561 tcgatcccaa tacactactt agaataccat tatggataat cacaattctc tttacactag
    19621 ccggattagc ttttcatttg accgcgcgac gattattagc aggtgaaata gacagcctga
    19681 aacacagaat gataaagaaa agcaaacttg agagaaatac aagaacagat gttcgcaaag
    19741 taaaagaatt gttgccagac agcatagaat acaatcccct agattacatt gatttgaaaa
    19801 aaggggtttt cattggctta gacaaagacg accaaccgca atatataaca ataaaagaat
    19861 ttcagaaaca acatgcagca atcataggta caacaggttc cggtaagggc attaccgcat
    19921 cggttttgct ttatcaggca attctgttag gcgaggctgt ttttgttgaa gatccaaaag
    19981 atgatgaatg ggctgtgcat gttcttaggg aagcatgtaa aaaagcagga aagaaatttg
    20041 ttgtaattaa tttaaacaga accaaccatc aacttgactt acttgctgac atatcacatg
    20101 aacaattaga agaattattt aatgcaggat ttagtctatc aaaaaaagga gaggccgcag
    20161 atttttatcg tatagctgat cgccgcgcag ccagaaatgt agccgcaatt cataaaaccg
    20221 gaatgacact gtatgattta ttcaacgatg acaacgtaaa atcaatagga gaagatgccc
    20281 cagcattttt aggtgaacta gaagaaattg ctcttgtaaa ttccgtcaat gcaaaaaatg
    20341 gattttctct taaagagatt tttgataatg gaggatgctg ctatatcatt gggtcaaccc
    20401 gaaatcaaaa aattatttct gcacaacgca tgatacttac gcgtttgatt cagatagctg
    20461 aaaccagaga cagaataaac acaactccac gtgttgttgc aatttttctt gatgagttga
    20521 aatatcatat ttcacgcccg acaatggaag gattaggtac agcacgagat aaaagcgtgc
    20581 atatatttat ggccttccag gcaatagatg atttaagaga ttgcccttct gatcttaatg
    20641 gcgattctgt aattggtgct gttattgaaa acgcaaaatt caagttaatc tataaaatcc
    20701 agaatccaga aacagcagaa tgggcagcca aaatgactgg ttcaatatta gttgacgatg
    20761 aaatgaggaa ggtgagaacc gacttatcat taacagaaaa agttgatact gaccgcatga
    20821 taagacaggc agaaagttat tatgtagaca gtaatatgtt tttaaatcta cctgaaagag
    20881 taggatttgt gttcacatca aaagatttac caaaagcaac taaaatgtct catataccag
    20941 caaacaaaga aaccattgaa ttgctatctt ttgagacaga acaaatagaa caacacaata
    21001 acaacgatgt gccttccagt ggtttatgag gttttactat gttaattcat gatttttacg
    21061 aaagaaaaag aatatcagct aacaacatgc tttgtctttt aaatttcctt aaggatgaaa
    21121 cgtattcaga ctttcacatt ataaaaagaa aattaggatt cacaaaaaaa agcagaaacc
    21181 cagtatataa attactaaac aaggctctta aagaaggttt tattatcaaa catgaaatac
    21241 catcatcaaa aagaaaatta actgtttggg gtattactat gcaaggatta gcaatggttg
    21301 taaaagccga tgacattacg ttccctagtt atttcgaacc cagcaaacta aaatactgga
    21361 ctcttgagca tcgtctttta aatcagcgag tgagaatatc tctggaaagt aaaggcgcta
    21421 ctgaatggat taacggtgat agtgcagcct tcatcgcacg ttattccggc tgttcccatc
    21481 gccctgatgg agtaataaaa caaccaactg gcgcaataat ggctattgaa acagaacgaa
    21541 caatgaaaac tcgtgctcgc tatataagca ttataaacag tcatcttacg gcaagagata
    21601 aaggaaactg gcattatgct ttgtacgtca tgcctgacac caaaagtaaa gaatcattaa
    21661 tcagactgtt cgactcaatc aaaactgtaa tgaggaataa tacacctgtg ccttttgatg
    21721 aaaaaaacag agagatgttt atttttagaa caattgatga actggaacaa tagttgatga
    21781 aaatattaat catattcgca ttatatatct tgtcgccttc actatatgcc aatgcagcgg
    21841 atatacaggg aaaagttatt cgtgtacttg acggcgatac catcgaaatt ttacagaata
    21901 aaacgccagt aaggattcgt ctggccaata ttgatgcacc ggaaaagaaa caggcttacg
    21961 gacgctggtc aactgaccaa cttaaaagcc tgattgccgg acaatccgtc agggtgacat
    22021 attcacacaa cgaccgttac ggtcgcatta tcggacgtgt attcacaaca ggcggtagtg
    22081 aagctaaccg ctttatggtg caatcgggtg ctgcatgggt gtatgagcat tacaacacag
    22141 ataacgctct ggcagatcta caacaggaag ctcgctcaca aaaacgaggt ttgtgggctg
    22201 accccaatcc cgttccaccg tgggaatgga gacataagta taaggtgaca aaatgaatga
    22261 ttgtttcggt tgtatgcatc catatcccgc cggtcactgg ttttattctt tacaggattt
    22321 acttactcca ctactggaaa atcctctttt ctacgtcttt tccttttttt tcgcgggtat
    22381 gataggtgca attatatcaa gaataaccaa attaattaaa acgatgaaac atggcaataa
    22441 caaaaaaata tcaatagata attatgacca aattgaaata gaacgctata tgacaaatga
    22501 agaggttggc agattagtaa tcaattttat gaaacgcacc aacggagaac cgttactaat
    22561 agtgttccca gaatatgaca atggagacga taatgacgat aaaaatactc gttgtgtcaa
    22621 atgacggcca tgaaaaacta attgatctaa gtccagttaa tgatttagct aaaattacaa
    22681 aatcattgcg tacatcagaa aacaggatgg tatgtgttat ccaggacaat aatcgtattc
    22741 tccgctggga cagaaactat gcctctcgtg caaaaaatca ctggcgaaag gtagctcccg
    22801 accgttttga gattttagga acagttgaac atattcatta tgttggtaag tgttaatatc
    22861 aggggacagt tcgtccccta tgccatttta atgatgcttt ttccagaatt cctggtatgc
    22921 ctccagtaac tccccgtgct tcatgtcatt agccgctgca atcgagcgga actcccgttt
    22981 aacttccata tcaacataaa ggttaagctg agcttttctc ccatcagcgt ttttacgcgt
    23041 cggattaaat ccgtgttgtg tatcctccag gcttggcggt tcgcctttgt tgttacgcgg
    23101 ttttggtggt acattagcca tcttatcacc tctataaaaa tataattata gaattatata
    23161 tcactgtgag agtttagtca gcaagtcaat aaccccttgg acaacttcgt cagctttctg
    23221 ccgtggacct ggaaaagggg attccgtcaa tgccagtcct ttatcctgtg cctggctgaa
    23281 cgaggtcata aaaggtattg cgccattgat aacctggaca ccacacggtt taagatattc
    23341 aagcgcggta cgatactcac tttcactttc actgactccg acaaaaacta cagccatctt
    23401 atttgttgag tgtcccttgt tacgtaatgc attcacggtt gtaaccgtcg ttctcaaatc
    23461 gtccacacta aaaccagacg gtaacacgag caaatcaacg atttctgcca ggctcaacag
    23521 tgatttagtt gcataagcag cactatcgat gacgactaaa tcccatatcc ccgattcaat
    23581 atgtttttta gcctgtgata ccgttccgca tccctgaata gtgacgggcg gttcaacttt
    23641 atatctcaat cgccgctgcc cccaatccag gaatgacccc tgatcaacat ccatatcaag
    23701 ccccaatacc ttccagtctg cctttgtgta ctctgtggca atagccctgc tcattgagga
    23761 ctttttcacc ccgcctttac cgttaaccag cgcaatagct accgtcatac gaccccctat
    23821 aaaaatattt ttatagaaaa atataattat agtatccgta ttggtgccaa gaattgcaac
    23881 aactatttga actacaggcg gcaagtgaag agataacttg tgaatataag gctttcacaa
    23941 ccaaattcag ccaaaacaaa aaacgatgtt ctattaacaa atatgcaaca taaaaacggt
    24001 ggaaaacgcc ctggaaaaca tgatcttttg agctgatttt gcagatccga caacgaacag
    24061 tgatccgatg gtgccgataa cgtccattat gtt
//
