LOCUS       NZ_CP063335            33851 bp    DNA     circular CON 17-JUN-2023
DEFINITION  Escherichia coli strain BS74R-D plasmid pBS74R-D_3, complete
            sequence.
ACCESSION   NZ_CP063335
VERSION     NZ_CP063335.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN16387362
            Assembly: GCF_016942475.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 33851)
  AUTHORS   Moser,A.I., Campos-Madueno,E.I. and Endimiani,A.
  TITLE     Complete genome and plasmid sequences of MDR Escherichia coli
            acquired by Swiss travelers in Laos
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 33851)
  AUTHORS   Moser,A.I., Campos-Madueno,E.I. and Endimiani,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-OCT-2020) Institute for Infectious Diseases,
            University of Bern, Friedbuehlstrasse 51, Bern 3001, Switzerland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye v. 2.7.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 445x
            Sequencing Technology :: Illumina NovaSeq; Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 06/17/2023 06:02:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,200
            CDSs (total)                      :: 5,077
            Genes (coding)                    :: 4,781
            CDSs (with protein)               :: 4,781
            Genes (RNA)                       :: 123
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 90
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 296
            CDSs (without protein)            :: 296
            Pseudo Genes (ambiguous residues) :: 0 of 296
            Pseudo Genes (frameshifted)       :: 82 of 296
            Pseudo Genes (incomplete)         :: 207 of 296
            Pseudo Genes (internal stop)      :: 46 of 296
            Pseudo Genes (multiple problems)  :: 38 of 296
            Pseudo Genes (short protein)      :: 4 of 296
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP063335.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..33851
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="BS74R-D"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="pBS74R-D_3"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018"
                     /collected_by="Institute for Infectious Diseases Bern"
     gene            join(32628..33851,1..930)
                     /locus_tag="IN878_RS24605"
                     /old_locus_tag="IN878_24625"
                     /pseudo=""
     CDS             join(32628..33851,1..930)
                     /locus_tag="IN878_RS24605"
                     /old_locus_tag="IN878_24625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247728.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /name="DNA topoisomerase 3"
     gene            927..1133
                     /gene="hha"
                     /locus_tag="IN878_RS24610"
                     /old_locus_tag="IN878_24630"
     CDS             927..1133
                     /gene="hha"
                     /locus_tag="IN878_RS24610"
                     /old_locus_tag="IN878_24630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="WP_000850859.1"
                     /translation="MKTKQEWLFQLRKCTSRDTLEKVIEINRYKLPLSESEAFYSAADH
                     RRAELVMNKLYDKVPSGVWKYVH"
                     /name="hha"
     gene            1151..1615
                     /locus_tag="IN878_RS24615"
                     /old_locus_tag="IN878_24635"
     CDS             1151..1615
                     /locus_tag="IN878_RS24615"
                     /old_locus_tag="IN878_24635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293133.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS family nucleoid-associated regulatory
                     protein"
                     /protein_id="WP_001293134.1"
                     /translation="MSELTKEDEYGIISRTMMNIRSLRVFAREIDFEQLLEMQEKLNVV
                     IEERREDAEREAAERQELEAKRQQAIEYIISLGLDPESLLAPVTADTVKTRRKAKGGVR
                     KAKYRFKDENGEIREWSGNGKRPLALQKLLDEGHFMEDFLIEKTKPEQAE"
                     /name="H-NS family nucleoid-associated regulatory protein"
     gene            2359..2454
                     /gene="dqlB"
                     /locus_tag="IN878_RS26210"
     CDS             2359..2454
                     /gene="dqlB"
                     /locus_tag="IN878_RS26210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinQ-like type I toxin DqlB"
                     /protein_id="WP_021534057.1"
                     /translation="MINMLIIVLRAVVAVANALIAVLELIRQFID"
                     /name="dqlB"
     gene            3116..3763
                     /locus_tag="IN878_RS24620"
                     /old_locus_tag="IN878_24640"
     CDS             3116..3763
                     /locus_tag="IN878_RS24620"
                     /old_locus_tag="IN878_24640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001694199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division plane positioning ATPase MipZ"
                     /protein_id="WP_000587671.1"
                     /translation="MIIVIGGDKGGTGKSHLATNLTVCLSQQGKRTGLVETDLNGSTKK
                     WNKRREQAGLPPVALNEAYGDISAKITKMADVAEILIIDTAGYDSTEFRTALKVADIVI
                     VPIDPLAQVEADSLQTVTKIVRDAQKINPRLAAHVLLYKCQPNTFSEQQELRDSLNSHD
                     YWLKPMKSTVSFLRAFVRAMNQGMGVHELKSNVSGASQAKAQIELLLKELEL"
                     /name="division plane positioning ATPase MipZ"
     gene            3838..4107
                     /locus_tag="IN878_RS24625"
                     /old_locus_tag="IN878_24645"
     CDS             3838..4107
                     /locus_tag="IN878_RS24625"
                     /old_locus_tag="IN878_24645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001086090.1"
                     /translation="MAKLELPELEQNQEVNATKFVQDAGKRPTENKTKLASFRIPNELL
                     EFIDNESKRLHRPKTKIIKAALLAYQDLDENELINLWFRADRND"
                     /name="hypothetical protein"
     gene            4348..4890
                     /locus_tag="IN878_RS24630"
                     /old_locus_tag="IN878_24650"
     CDS             4348..4890
                     /locus_tag="IN878_RS24630"
                     /old_locus_tag="IN878_24650"
                     /inference="COORDINATES: protein motif:HMM:NF022440.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2806 domain-containing protein"
                     /protein_id="WP_251301857.1"
                     /translation="MLYEPTRIRKKAKAEAEAKRTELISRLELEGIEKRAVERFLKRET
                     KRQENIENITMQAAQSLSESDNVSDIDEDWIEAFFRECEDISDEQMQMLWGRILSEEAK
                     SKGSFSRRTLKLLSTISKEEANLITYFGKFVWQANKLTPILFTDENGDTEGITFDKLSV
                     LDSLGVIQQGIGYSLTS"
                     /name="DUF2806 domain-containing protein"
     gene            complement(4879..5607)
                     /locus_tag="IN878_RS24635"
                     /old_locus_tag="IN878_24655"
     CDS             complement(4879..5607)
                     /locus_tag="IN878_RS24635"
                     /old_locus_tag="IN878_24655"
                     /inference="COORDINATES: protein motif:HMM:NF028536.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAP2 family protein"
                     /protein_id="WP_072651034.1"
                     /translation="MPYLSNKRLLAEMSIALVMAIVATLTLEHSQIDLMVADWFYLGMG
                     HWMVAKQAFLPDLLLYSGLKKLLMAMLIYLLVATICRAYHEKKGNAITAKWLVPVTKFR
                     VRELAYLVLTLILVPTVVASLKAYTHVVCPVHLTIFDGTLPYLPMLDSMRNTIPDKCFP
                     AAHASSGFALFAFAFAPSLRRRRGAIIIVVMALGWAMGCYKMIIGDHFLSHTVVSMMLA
                     WAMSAGLAWVFFKKGEQSRG"
                     /name="PAP2 family protein"
     gene            complement(5679..7304)
                     /locus_tag="IN878_RS24640"
                     /old_locus_tag="IN878_24660"
     CDS             complement(5679..7304)
                     /locus_tag="IN878_RS24640"
                     /old_locus_tag="IN878_24660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_049589868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine--lipid A transferase MCR-1.1"
                     /protein_id="WP_049589868.1"
                     /translation="MMQHTSVWYRRSVSPFVLVASVAVFLTATANLTFFDKISQTYPIA
                     DNLGFVLTIAVVLFGAMLLITTLLSSYRYVLKPVLILLLIMGAVTSYFTDTYGTVYDTT
                     MLQNALQTDQAETKDLLNAAFIMRIIGLGVLPSLLVAFVKVDYPTWGKGLMRRLGLIVA
                     SLALILLPVVAFSSHYASFFRVHKPLRSYVNPIMPIYSVGKLASIEYKKASAPKDTIYH
                     AKDAVQATKPDMRKPRLVVFVVGETARADHVSFNGYERDTFPQLAKIDGVTNFSNVTSC
                     GTSTAYSVPCMFSYLGADEYDVDTAKYQENVLDTLDRLGVSILWRDNNSDSKGVMDKLP
                     KAQFADYKSATNNAICNTNPYNECRDVGMLVGLDDFVAANNGKDMLIMLHQMGNHGPAY
                     FKRYDEKFAKFTPVCEGNELAKCEHQSLINAYDNALLATDDFIAQSIQWLQTHSNAYDV
                     SMLYVSDHGESLGENGVYLHGMPNAFAPKEQRSVPAFFWTDKQTGITPMATDTVLTHDA
                     ITPTLLKLFDVTADKVKDRTAFIR"
                     /name="phosphoethanolamine--lipid A transferase MCR-1.1"
     gene            7468..7725
                     /locus_tag="IN878_RS24645"
                     /old_locus_tag="IN878_24665"
     CDS             7468..7725
                     /locus_tag="IN878_RS24645"
                     /old_locus_tag="IN878_24665"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2806 domain-containing protein"
                     /protein_id="WP_223369243.1"
                     /translation="MRVFIICIFKSKNGRIGYYGTVFSVEFQSDDSSTWKLPIGTALLT
                     PIGQELMKICGSTPDIAYLNKFLNKINVEGSQVKLSIINM"
                     /name="DUF2806 domain-containing protein"
     gene            complement(7877..8404)
                     /locus_tag="IN878_RS24650"
                     /old_locus_tag="IN878_24670"
     CDS             complement(7877..8404)
                     /locus_tag="IN878_RS24650"
                     /old_locus_tag="IN878_24670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001473365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2726 domain-containing protein"
                     /protein_id="WP_000577043.1"
                     /translation="MIFNRNKKRDEQHNSAVVLPSAENVFSDFIKNNPALTTNAFTAIG
                     EVDCFTKVPLLSNNESEFLGILSRNIIPDYSVFPKIRLIEFVRPHGSEEAVKDLIREVQ
                     NITCDFVLKSYDETVLAVIQFGETATVRQQKKKLIIQRVCAMTGISFFEFKNTVDMMGS
                     EDFCQFLRDDEE"
                     /name="DUF2726 domain-containing protein"
     gene            complement(8539..8943)
                     /locus_tag="IN878_RS24655"
                     /old_locus_tag="IN878_24675"
     CDS             complement(8539..8943)
                     /locus_tag="IN878_RS24655"
                     /old_locus_tag="IN878_24675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012421203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_012421203.1"
                     /translation="MKDNIVDFQRIRDSMNDHSTDVANDAVYSDKKKISRFFYLLTPVR
                     YLLAASLYLVVVIPLGILAGFRFLLQFLGGIAVMGLTIAWYMGADVSSYVVLAAWIALT
                     VCGCAEQIFEWWIESRFAFRLFGIGRTPEE"
                     /name="hypothetical protein"
     gene            complement(8956..9192)
                     /locus_tag="IN878_RS26020"
     CDS             complement(8956..9192)
                     /locus_tag="IN878_RS26020"
                     /inference="COORDINATES: protein motif:HMM:NF013235.2"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="WP_071699791.1"
                     /translation="MKDYKYPDYPAFKRDVLNKSVKEIMKHTEVKNLSFVVSEKIGRKV
                     YKLKFSYTIGYEGDTREDSEFTNMFDKMYPPEN"
                     /name="RepB family plasmid replication initiator protein"
     gene            complement(9179..9820)
                     /locus_tag="IN878_RS24660"
                     /old_locus_tag="IN878_24680"
     CDS             complement(9179..9820)
                     /locus_tag="IN878_RS24660"
                     /old_locus_tag="IN878_24680"
                     /inference="COORDINATES: protein motif:HMM:NF013235.2"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_251301858.1"
                     /translation="MTTNKTSLSRLTKVRHRNELNSTLSTLPMAAKKVLFLAMCQINSK
                     NEFDDDHIFYVTVADYIKWVQVKPDAAYLALRDGSNILDTTLLKLKHDEILELSSDLGF
                     KFTKSNVPDSMNLSLTVFSTYYRNEGRVGIKFTKEAKRFLCKLIGEEKRYTTQVLLSVV
                     RLTSVNAASLYQLIRKIYSNNSRANSFEMTIDELKDELNLYTIGAGGEGL"
                     /name="replication initiation protein"
     gene            11234..11749
                     /locus_tag="IN878_RS24665"
                     /old_locus_tag="IN878_24685"
     CDS             11234..11749
                     /locus_tag="IN878_RS24665"
                     /old_locus_tag="IN878_24685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025391.1"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="WP_001025395.1"
                     /translation="MNIQEALNVFGLSGELTEKDIKAAYRKAALKYHPDRNPLGAELMK
                     AVNAAFDVLMANIDKINQFQSTDEHARYNYGDDLEKVLNVLSGLSGLVFEVIGNWVWIS
                     GETITHKETLKEIGCKWAAKKKQWFYRPDEHKSYWNREEHTIEEIRAKYGTTGQRRATG
                     WQRVETRA"
                     /name="J domain-containing protein"
     gene            11854..12396
                     /locus_tag="IN878_RS24670"
                     /old_locus_tag="IN878_24690"
     CDS             11854..12396
                     /locus_tag="IN878_RS24670"
                     /old_locus_tag="IN878_24690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001083906.1"
                     /translation="MNSFFEQYHPVFEVVCRILGNGWRVNKLDDCSSRIKLTSPQFKNY
                     SVHIRMEKDRFSVVGSVDSRSWRSPHHVCTLSRKRNPVDIAADIERKILVNASQEVLQA
                     IEYEKHQVEKKDEILILKGMLSQLVQLESWYGALTGFKAENGLNGKVTEQGDSYDLQIR
                     GLSIDQLVKITGYLKQL"
                     /name="hypothetical protein"
     gene            12393..12644
                     /locus_tag="IN878_RS24675"
                     /old_locus_tag="IN878_24695"
     CDS             12393..12644
                     /locus_tag="IN878_RS24675"
                     /old_locus_tag="IN878_24695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001565860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001230707.1"
                     /translation="MRKNKGDVTYFLEKEGDNYRLTKRIKARTNVKIGNKTTKITLYDA
                     VLNENELQHIDFTCAGLREDDETPVKNLIKEFMLNETR"
                     /name="hypothetical protein"
     gene            12631..12858
                     /locus_tag="IN878_RS24680"
                     /old_locus_tag="IN878_24700"
     CDS             12631..12858
                     /locus_tag="IN878_RS24680"
                     /old_locus_tag="IN878_24700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000801440.1"
                     /translation="MKPDNTPENVKKLRLKAGLTQKECSHIYGVGLRTWQKKEEVNTQN
                     SQSLSLVEFEFLLLLAGEHPEYVLCKRESK"
                     /name="hypothetical protein"
     gene            13312..13611
                     /locus_tag="IN878_RS24685"
                     /old_locus_tag="IN878_24705"
     CDS             13312..13611
                     /locus_tag="IN878_RS24685"
                     /old_locus_tag="IN878_24705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000650309.1"
                     /translation="MKCSSVFTSTTNHVFTFERVTLCTIILMHKDTGQQYVVIFTDNNK
                     IRDYKAGIVPQFGELKQSDVDLVLFYRDEYEKYFDSLKDGDECLSFKDFIECLC"
                     /name="hypothetical protein"
     gene            13702..14052
                     /locus_tag="IN878_RS24690"
                     /old_locus_tag="IN878_24710"
     CDS             13702..14052
                     /locus_tag="IN878_RS24690"
                     /old_locus_tag="IN878_24710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000854261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000854259.1"
                     /translation="MKTLKQAAMQFASDLRNNRCFKAAYNDALLELDREDLNAIVQCTF
                     LFEPKRTLAELDKLIKKIEVEEDYEFCVSLDKGKGLHEVRTFKSEREALDAYRILTLYG
                     YTVTIEKKEGND"
                     /name="hypothetical protein"
     gene            14357..14605
                     /locus_tag="IN878_RS24695"
                     /old_locus_tag="IN878_24715"
     CDS             14357..14605
                     /locus_tag="IN878_RS24695"
                     /old_locus_tag="IN878_24715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005653200.1"
                     /GO_function="GO:0003729 - mRNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family toxin"
                     /protein_id="WP_000520549.1"
                     /translation="MGKTDKLLAKFLNSKKTFEWDELVVLFSSLGYVKKEMQGSRVRFF
                     NAEINHTILMHRPHPESYIKGGTLKAIKQNLKEAGLL"
                     /name="type II toxin-antitoxin system HicA family toxin"
     gene            14602..14949
                     /locus_tag="IN878_RS24700"
                     /old_locus_tag="IN878_24720"
     CDS             14602..14949
                     /locus_tag="IN878_RS24700"
                     /old_locus_tag="IN878_24720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="WP_000681613.1"
                     /translation="MKHLKYKGYLGTVEPDFENNVLYGKLAFIRDLVTYEASTLAELEQ
                     EFKTSVDLYLQSCVEDGKEPDTPFKGVFNVRLDPELHRRVAEMAMEEDLSLNAFVNKAL
                     EKEVSNHRAGA"
                     /name="type II toxin-antitoxin system HicB family
                     antitoxin"
     gene            15310..15813
                     /gene="taxA"
                     /locus_tag="IN878_RS24705"
                     /old_locus_tag="IN878_24725"
     CDS             15310..15813
                     /gene="taxA"
                     /locus_tag="IN878_RS24705"
                     /old_locus_tag="IN878_24725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000781813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome-coupling protein TaxA"
                     /protein_id="WP_000781813.1"
                     /translation="MKMIAFRLSDDELKFAEHNAILSGFTSINAFAKHNVLNIETKPVN
                     IPVNNEPAKLVSVRLYPHEIELVKRNAALHGMSMSREIAIRVRQSLLKSEVCLYPDEVK
                     ELKKLSTAVDRVGRNIHFIIKGERFCTVNDPDFRKDVIEVIELCKQIDSKLETLTKSVV
                     NRFG"
                     /name="taxA"
     gene            15817..17046
                     /gene="taxC"
                     /locus_tag="IN878_RS24710"
                     /old_locus_tag="IN878_24730"
     CDS             15817..17046
                     /gene="taxC"
                     /locus_tag="IN878_RS24710"
                     /old_locus_tag="IN878_24730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001329504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA relaxase/nickase TaxC"
                     /protein_id="WP_001329504.1"
                     /translation="MGVYVEQEYRIKRAKGTGRDPKSPKLSGRHIHASKSAFNHKVRHG
                     ADKKAYTWTPTKEVTFKITGSGKTAAGIKNGIDYITRNGELEAYCYDGKGSEQTGKGED
                     FNREFTSTLSKGNDYSRTYRGENIDHVKNMVFSPPPEAGVSREDALKATVEFLKETYPN
                     HAFVAVYHDDKEDHPHVHVNIKLRDEETGRRLRLTKSETRKFRNGFHRKLKGMGYDVTA
                     TWKKDPERKREIERLQAENPKRLRNVYKVVDFGETSYQNKAGEKRTPFLTYETLKGGKQ
                     VTIWGKDLKNHFESEKLQPGTLIKVKKLAPTLVRSPMFNDDGTVAGYRETHRNNWQIEN
                     IALERNRERQVHERETRQPEESDVKKQLSRKHEQGHNIGFALEHGFTKDSEEHKKLRIQ
                     QERNWKGLGF"
                     /name="taxC"
     gene            17123..17416
                     /locus_tag="IN878_RS24715"
                     /old_locus_tag="IN878_24735"
     CDS             17123..17416
                     /locus_tag="IN878_RS24715"
                     /old_locus_tag="IN878_24735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134733.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]; GO:0016987 - sigma factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="WP_000134733.1"
                     /translation="MTEHDAICISALHQIFSDEEHLSEQQKDIILMYAYGYTLNEIADF
                     KGLKPSTVRKYLDSVRAELGGVSLAGIRTLVLIRTNALLVSSLSRISERGNL"
                     /name="sigma factor-like helix-turn-helix DNA-binding
                     protein"
     gene            17413..17628
                     /locus_tag="IN878_RS24720"
                     /old_locus_tag="IN878_24740"
     CDS             17413..17628
                     /locus_tag="IN878_RS24720"
                     /old_locus_tag="IN878_24740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="WP_000760375.1"
                     /translation="MKKYLLFALPFFVVGCSEEVKSVDWWGQHLTEAKQKQAECEKSGS
                     DSQNCKNVKQALFIQSQKDAPVPTFD"
                     /name="EexN family lipoprotein"
     gene            17984..18604
                     /locus_tag="IN878_RS24725"
                     /old_locus_tag="IN878_24745"
     CDS             17984..18604
                     /locus_tag="IN878_RS24725"
                     /old_locus_tag="IN878_24745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_000157549.1"
                     /translation="MASLFPALLLCAASVHPDTINDIARVESGFNPYAVAEIIPERERG
                     SYGKSVISHMPKSKEEALTVIREIENRKRRYSVGLMQITSSNFSFYSTSAEKLLDSCEN
                     LSVFEKIIVDCYKRGRSLENALSCYYTGNFSNGKRKEKEFNNTSYVERIGYTGNEKKYV
                     VPGTRSNGGEQRKNRSHNASVIWPETILKSAFVDNSHPTKVIN"
                     /name="lytic transglycosylase domain-containing protein"
     gene            18618..18944
                     /locus_tag="IN878_RS24730"
                     /old_locus_tag="IN878_24750"
     CDS             18618..18944
                     /locus_tag="IN878_RS24730"
                     /old_locus_tag="IN878_24750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_000008647.1"
                     /translation="MSFKKSVCNRISSSVTAVMQRKNKVVMAVAGATVASPAFADGFSK
                     AETLLEKVKTGLSGLSLVTVTIACLWVGYKVLFGGSTIRECSPIIIGAIVIASAAEVAS
                     MMVN"
                     /name="TrbC/VirB2 family protein"
     gene            18963..21710
                     /locus_tag="IN878_RS24735"
                     /old_locus_tag="IN878_24755"
     CDS             18963..21710
                     /locus_tag="IN878_RS24735"
                     /old_locus_tag="IN878_24755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
                     /protein_id="WP_000105985.1"
                     /translation="MSTLYKAMTRPAMYVGVPVVPLTVVAGALFLAGVYISKLIWLAIP
                     VAVFVLRMITKQDDHIFNLYFLKLKMLGNSVCNRFFGARAFLSGQYEAVEIDEFVNAMK
                     LNERITTGKYIPYSSHVDKNIVKTKNGDYVATWQLMGINFESISAEMLETIDSQVATLV
                     RSFSGLPVSFYNHSCRASFYDAFTTKSGNKYADIISDCYYGSMKKNKFKGNTLYFTLIY
                     RPDGRVEKLEKRKKSIKEKKDDINIHVKRMNEMINTFSGALDKFTCKLLGMYEENGKVF
                     SSQLSFYNYLLTGKLQKIRVTDSPVYNVLGGVDVFFNHDTGQICRIDGNKFFRSIEIKD
                     FCSETASGVFDVLQYSDADYIITHSYTSMSKSEALSTIKRAEKQLKSTEDDAVTQLQEL
                     EKAKNDIVSGDISFGYYHFTLMVMADSIRELDESVSKITADFTDLGIIPALSTMSLPAA
                     YFAQLPAVFHLRPRLSPVSNVNFVELASFHNFYQGKRDKNCWTEAVAILKTPSKQAYYL
                     NLHNSVLFKDETGEKNLANTKVIGTAGSGKTMFLSYLACSLQKYNNPETFADSAKNKKL
                     TCVFLDKDRGAELCIRMLGGEYYTVKSGEPTGWNPFALEATKRNRIFVKQLMEILCTRN
                     GERLSTRERLLISESVDAVMDFPPGEMREYGITRMLEHLMQRDDRDEQENGIILRLSQW
                     ANGQAHGWVFDNAKDTFNIQHVNNFGIDGTEFLDDPMVCAPITFYLLYRITQLLDGRRL
                     VIFLDEFWKWLQDEAFSDFVYNKLKTIRKLNGLVIPATQSPDEILKNKISRAVVEVCST
                     SIYLANPDADYNDYVEGLKLTPEEFNIVKNLDPMSRQFLIKKSSLKKGDGKSFSALATL
                     DLSGLGGYLKILSASADNLEIFESIYHEGMEPDDWVPEYLERAI"
                     /name="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
     gene            21722..22438
                     /locus_tag="IN878_RS24740"
                     /old_locus_tag="IN878_24760"
     CDS             21722..22438
                     /locus_tag="IN878_RS24740"
                     /old_locus_tag="IN878_24760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000832283.1"
                     /translation="MKRVKTLMLISLLTASFYSSAGIPVAIDASPEWAVEAARWTERLK
                     QWSETAQHYQSQIQAYKDQLATATGIRNIAAFTNELSNLQSELTNIYKQGNSYISDFTS
                     NPEGALSSQAKNLFSKYGAFDMCNTGYERNDNLCKARIVSTAASIEQGNEINKQLSSAM
                     SQIQSLSSRIEASKDIKESQDLANALQAQSLKMQAIKMQYDVWNNKNKADHEMLVTQEQ
                     EAFIKQQKEAEPLTFD"
                     /name="type IV secretion system protein"
     gene            22450..23544
                     /locus_tag="IN878_RS24745"
                     /old_locus_tag="IN878_24765"
     CDS             22450..23544
                     /locus_tag="IN878_RS24745"
                     /old_locus_tag="IN878_24765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001677777.1"
                     /GO_process="GO:0030255 - protein secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000046889.1"
                     /translation="MAQGFFVKYNSTVMDSVDKISSSYQTQFANDIMSLATVSVTLYVL
                     WKGYQILASKTQTPLQDLVWDLSKFAIIIMFITNADGYLTAATDALQGMKDGFSGGVSV
                     WQTLDNLWKSTQNLGAEIYSLDKSTYVKDQGVVGQFLIWTGSLILMAVSVVVFLTADVT
                     MKLLIITAPIFIFCLMFGFIRSMFNNWLQSLFSSILTVLFASLVIRIAMDFQGMILSHA
                     IRAAQTGNVNLVSTGAMGFMAGFLGALLVLIAKGFAVQLAGAGVEGAVQGAAMMGLGAA
                     GMATGKSLMLGGRAGLGFGLGMAGRTGMNSLSGKAGNLMGRGARTAAEWAGEKGYQALA
                     PTGALGMKARRLASLEKARARNAA"
                     /name="type IV secretion system protein"
     gene            24059..24745
                     /locus_tag="IN878_RS24750"
                     /old_locus_tag="IN878_24770"
     CDS             24059..24745
                     /locus_tag="IN878_RS24750"
                     /old_locus_tag="IN878_24770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_001290765.1"
                     /translation="MSEKIEKKIETAKSFERQLYAENERSKKNAWRVAVAASLLSLCLG
                     AAICVLVPLKEKELAIVAVGEKTGRTELITQVKQEKILQSEALGRYFVNTYITLREGYN
                     YPSLQYDYETVQLYSSNTVKDDYLRLYNSDMAPDKIYHNNGSYVAVEVISNIISDATAP
                     DKLASVRFKKTTRNFTTGQVSVSYWTARVTYRFEPEKSVKSSSRELNPLGFTVTSYQTD
                     REVRGE"
                     /name="type IV secretion system protein"
     gene            24742..25650
                     /gene="virB9"
                     /locus_tag="IN878_RS24755"
                     /old_locus_tag="IN878_24775"
     CDS             24742..25650
                     /gene="virB9"
                     /locus_tag="IN878_RS24755"
                     /old_locus_tag="IN878_24775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001299943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein VirB9"
                     /protein_id="WP_001329500.1"
                     /translation="MMKKLFIATCLLLPGLVYSAATPLPSGFDARMQTVSYNGANTTVI
                     RSKTGFLTSVVFDEGEAVISAKAGFPAGWEITTDDNVVYINPRPVVQEQEGDEGEKLKK
                     VFQPTEKEWDTNLFVRTTKRIYSLDLILLSEEKQAQPAYVVQFRYPSEIAKKNAEEVRL
                     AKEKQEKLRQKKLISESFEKADAPKNWNYFMRVNEKYDSRRIAPDFAYDNGIFTFLGFN
                     SGKVFPAPFAVRDGQEQTLAFNVETKGKYKIMVIHNVNDKFVLRYGNSVVGVVNKSFGK
                     VLTDQRNTSSPAVERVEVNND"
                     /name="virB9"
     gene            25643..26761
                     /gene="virB10"
                     /locus_tag="IN878_RS24760"
                     /old_locus_tag="IN878_24780"
     CDS             25643..26761
                     /gene="virB10"
                     /locus_tag="IN878_RS24760"
                     /old_locus_tag="IN878_24780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB10/TraB/TrbI family type IV secretion system
                     protein"
                     /protein_id="WP_000131271.1"
                     /translation="MTDMKKTDDLVDDANQSKLESKPVHDIGDIRNKNNRMRSGFLFGL
                     MAVLVIGIFALKTYKNYFADDQQKASESTGDTSISQVSKIRTGLGQNFDPVENKAIINP
                     GATGSGNTVSDGHKEVPQEGFRKYLSIPVAGQGGSQTGASGSSRTSQTSEPQEERKESK
                     ENVPGKSGMKVTAINLDPDLYIEENRLIPCALTTRFVSDVAGRISCVFTEDVWSANHHT
                     KLLEQGTKAFGRYQTGTLNHGQGRMFVMWEQLRTPDNKRIDMVNTAAAGPLGEAGIDGW
                     IDSHFWERFGGSLMLSMVQDVAAAAADNAPGKDRNVDYTENSRQAMAEMAKVALENSIN
                     IPPTMYKNQGDIITIMVGEDIDFSDIYELKVK"
                     /name="virB10"
     gene            26763..27791
                     /gene="virB11"
                     /locus_tag="IN878_RS24765"
                     /old_locus_tag="IN878_24785"
     CDS             26763..27791
                     /gene="virB11"
                     /locus_tag="IN878_RS24765"
                     /old_locus_tag="IN878_24785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401678.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_077250700.1"
                     /translation="MSGVIPVSISNKSLDFYKNQVFQSFLDIEGLTEIAVNRPGEIWTE
                     INGDWTFHNNNSVTFDFCKRFSHTLASFRGDEIGETKPLLSATLESGERVQVVFPPACE
                     RNTISITIRKPSTRQITHKEYVANGFYDYVQSGKKHRTYDDELLDLFRARNIAAFMELA
                     VAAGKTIVFAGATGSGKTTYMKSLIDFIPLNTRLITIEDAEEIKFFIHKNYVHLFYPSE
                     SGSDSGSIITAAKLIKSCLRMKPDRILLAEIKGGDAWDFVKVAGSGHSGSMTSIHAASA
                     KDAIIQMVTKCYQNRECQNLPFDVLRKIIMDSIDIVVHVGRDGVVRHMSDIYYKGAECE
                     NF"
                     /name="virB11"
     gene            27778..29640
                     /gene="taxB"
                     /locus_tag="IN878_RS24770"
                     /old_locus_tag="IN878_24790"
     CDS             27778..29640
                     /gene="taxB"
                     /locus_tag="IN878_RS24770"
                     /old_locus_tag="IN878_24790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome-coupling protein TaxB"
                     /protein_id="WP_170324155.1"
                     /translation="MKTFNKSQSVFIFAVMLVAAWFAGSFIFFVLYFSQIKNLKPLKAV
                     FRSIDAYRMDIFTDSLTLSVVTTDIRVLAFVALGAGFVVSLIIPVAALIKLNEKKENIF
                     GDARFATINDIRESNSFTLDGDEKDGIIVGIKDKKIIRYVGAAFSAMGAGTRAGKGAGI
                     VITNLMKYWWSVIILDPKRECFNITSLIRKVILGHEVYKFDPFSSVTHRFNPLYYVSMG
                     TSEGFNQLENLSLIIYPYKTDGADAGSYLNKTAGGVFKSYAVALWFMIKNDKAGLKTLD
                     IEPVFSMSKINQLFERAEPEHLLSFMNDIRSELRGKDKTLADIGVAGLKAFIEMEDKTK
                     AQLKSNFLNGLSPFANPNVANATDGNDFDLRQVRKKRMTIYFCISGDNARLAEKITNIF
                     FQLAIQVNLEKMPTDDPEIKHDCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQV
                     GSQLEEIYSYAGSKTLLASAPCKIVYSASDVKDARELSEAMGTRTVTIGSKSKSRSRGG
                     TSRSESESLIERPLVTTNELLTLKFSEEILAMKGENPIRCEKAFYYLNEYFFGDFVKVA
                     PELANIFPRKKGKLVMPPQKVFENEIVAKGYLVVKDVPDLDKAA"
                     /name="taxB"
     gene            29649..30071
                     /locus_tag="IN878_RS24775"
                     /old_locus_tag="IN878_24795"
     CDS             29649..30071
                     /locus_tag="IN878_RS24775"
                     /old_locus_tag="IN878_24795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001353737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="WP_015059903.1"
                     /translation="MMKKLVFLLISILAGCSSPPEPTPVQFEKANEVINPSLPYVPDFH
                     GVIKSDVSGKGWVYEITSLSGVQARTPTFYYALAHADRIVVTTHDAGLWFRIRDLLKME
                     GATAVVEWRNEKSFLPEQVKIVFIKAQNEVKNDWKK"
                     /name="cag pathogenicity island Cag12 family protein"
     gene            30055..30360
                     /locus_tag="IN878_RS24780"
                     /old_locus_tag="IN878_24800"
     CDS             30055..30360
                     /locus_tag="IN878_RS24780"
                     /old_locus_tag="IN878_24800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000147044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_000147044.1"
                     /translation="MTGKNRVVLPALLALGLISTNANASDPCASVLCLYGKAVGQGGGS
                     ECRSAEKDFFNILKKKKGSIRWSKTFDARKAFLNQCSTADPAAISKIMSKFGKVKG"
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            30366..30620
                     /locus_tag="IN878_RS24785"
                     /old_locus_tag="IN878_24805"
     CDS             30366..30620
                     /locus_tag="IN878_RS24785"
                     /old_locus_tag="IN878_24805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000415096.1"
                     /translation="MEKQTTDLLNVIKTGHSGSIAGNPAHALDDKTMNAIIHNYVATIV
                     LGKAGNCKETPLTKYCSRTMPERISVEEINEFKIYPELF"
                     /name="hypothetical protein"
     gene            30723..31031
                     /locus_tag="IN878_RS24790"
                     /old_locus_tag="IN878_24810"
     CDS             30723..31031
                     /locus_tag="IN878_RS24790"
                     /old_locus_tag="IN878_24810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000647576.1"
                     /translation="MKARSVRVAGIEIIDSVKTVAFVFTETLLFMVWFSAIVYGLYRVV
                     IVLWDDPLKPQSLMEFLNFIVELYSYVLPSLAVIAVALIAVLSICKILSAIWEGRKQ"
                     /name="hypothetical protein"
     gene            31028..31522
                     /locus_tag="IN878_RS24795"
                     /old_locus_tag="IN878_24815"
     CDS             31028..31522
                     /locus_tag="IN878_RS24795"
                     /old_locus_tag="IN878_24815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001215543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="WP_001215680.1"
                     /translation="MRHFLKALSFVVSLLPATLCAAEIQGKVIRVLDGDTIEIKTLPAK
                     IVVYEVPIRVRLINIDAPEKKQPFGRWSTSQLKTLVAGKQVTVSYSHKDRYGRIIGHVF
                     TTNGTDASRFMVQSGAAWVYERYNVDESLPALQREAQEQKRGLWADANPVPPWEWRYKH
                     N"
                     /name="thermonuclease family protein"
     gene            31538..31942
                     /locus_tag="IN878_RS24800"
                     /old_locus_tag="IN878_24820"
     CDS             31538..31942
                     /locus_tag="IN878_RS24800"
                     /old_locus_tag="IN878_24820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001576899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001218543.1"
                     /translation="MALSPKEKKELQQRFEKQLLPDLDMSFELNGEVYKFNFDKNESGD
                     YIDSFTQAVWGGYQDAEEWEKYGKHQETELPECPEPVEGWCDCDKCKSMIFHKEKNIYV
                     CLSCHKQTEPFLPIDWNSNDYDWLPYEDEY"
                     /name="hypothetical protein"
     gene            32048..32623
                     /locus_tag="IN878_RS24805"
                     /old_locus_tag="IN878_24825"
     CDS             32048..32623
                     /locus_tag="IN878_RS24805"
                     /old_locus_tag="IN878_24825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001199074.1"
                     /translation="MQYALVDALERKFLLDALEFGVLKDWKENPVKELPDIDESVHPFH
                     VCYGGYLLNPGVSDSDISRKIKDQTGFWLAAIDDTRMDCHSIAYYDIHTLPLILCGHQK
                     IVPFAALIKADECIISKIASYSGFAVTAFLRIKDQDIATNILNREGIFAFNGCERRFRQ
                     PVSEDNWQQAVSEERAIRCANRLIQCKG"
                     /name="hypothetical protein"
     ARG             complement(5683..7304)
                     /name="mcr-1.1"
                     /gene="mcr-1.1"
                     /gene_name="phosphoethanolamine--lipid A transferase
                     MCR-1.1"
                     /tool="amrfinderplus"
                     /drug_class="COLISTIN"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          complement(8957..9826)
                     /name="IncX4"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.771"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          15818..17043
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.511"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          22451..23517
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.719"
                     /coverage="99.0"
                     /evalue="2.6999999999999997e-172"
     Typing          24060..24742
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.4399999999999998e-137"
     Typing          24743..25647
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.669"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          27779..29637
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="98.71"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 aaagcatacc aggaagtatc ggttgccatt cagtgtggtg atgagtcgtt ctatgcccgt
       61 gccagaaaaa caactgacag cggatttgag gcgtttcttg gcgcggaaac cacagacgaa
      121 ggtgaatcag aagataatga tgattccgct tttgaactgc tctgtaaaat tcgcacagga
      181 gaaacactga cgacaaaaga agttattgtt aatgagaaga aaacaacacc gccgccgtta
      241 ttcaccgaag cctccttgct tgctgcgctt gttcgtgtcg cggattttgt cactgatcca
      301 acaattaaaa aattgttgaa ggataaggat aaagacaaaa aagatgaaca tggtggcatt
      361 ggtacgccag ctacccgcgc aaccattctg gaaacgctga agaaaagaaa ctatatcacg
      421 ctggaaaaag ggaaacttat tcctactgat accggatatg cgcttattga tgccctgcct
      481 ggtatagcgg ttaatcctga tatgacagca ttatggtctg aaaagcaggc tgccatagaa
      541 aatggcgacc tgacggttga acagtttatt aatgatctgt acggtgaact gacaggcatg
      601 atttctgatg ttgacctggg cgagatgaag attgaacccg ctgcgccagc agaggcggtt
      661 tcaacgcctg gactctccct gcccttcctg tggtaaacat attgttatca ggccgaaagg
      721 ttatttctgt accggatgtg aatttaaaat ctggagtgag ttttctggta agaaaatcac
      781 ccaggcacag gccgaaaaac tggttaaatc agggaaaacc gatttgatta agggatttaa
      841 aagaaaagtg gtggaacgta tgatacagtt cttgtccttg aggataagaa aacagggaag
      901 ctgggttttc cggcaagggc taagaagtga aaacaaagca ggaatggctt tttcagttaa
      961 gaaaatgtac atcaagagat actcttgaaa aagttattga gattaaccgt tacaaactgc
     1021 ctttatcaga atcagaggca ttttattctg ccgcagatca tcgccgagca gaactggtga
     1081 tgaataaact ttatgataag gtgccttccg gcgtctggaa gtacgtacac taaataagag
     1141 gattaattat atgagcgaac tgactaaaga agatgaatac ggcattatca gccgtactat
     1201 gatgaatatt cgttcattgc gtgtttttgc ccgtgagatt gattttgagc agttgctcga
     1261 aatgcaggaa aagctcaacg ttgttattga agaacgtcgt gaagatgctg aacgtgaagc
     1321 ggctgaacgc caggaacttg aagccaaacg tcagcaggcc attgaataca tcatatcttt
     1381 aggtcttgat cccgaatcac tccttgctcc tgtaacagca gatacagtaa aaaccaggcg
     1441 gaaagccaaa ggcggagtaa gaaaggctaa ataccgcttt aaggatgaaa atggcgagat
     1501 cagagaatgg tctggtaatg gcaagcgtcc gcttgcttta cagaagctgc ttgatgaggg
     1561 gcatttcatg gaagatttcc tcattgagaa aactaagccg gaacaggcag aataacccgc
     1621 caggtataca tcacacagac atacacatag gtatgtctgt gtgacatacc tatgtacagt
     1681 gccagatggc gttgctacgt gaaaaataac ctaccctacc cctgcttttt tcgcagattt
     1741 tacgtagcac accgttgcta tagcattcat ctaaaaagct gaatgtcctt ttctgtcgct
     1801 gttgcatttt aattcactga aaaatattga gtaatgaaaa tgccggtaac gcgtcaagct
     1861 gttggccaac gcgacaggca gtattggaag caacaaaaaa aatgaaagaa aaatccctca
     1921 aatgaaggag aaaaaacgga actacagccg aacgacaggc acaaaaaacc cgactggtaa
     1981 tcgggctttt tgcgttttcc agtcttgagt tggtggctct gaccggagaa ggttactcta
     2041 cacctaacgt ttacatttta ttcactatgg tgctgtaaag caactaaatg tggttaagga
     2101 accacattta gtggtgtaac aggtgttttg tgtagcgtat aatcagtcag ttagtcatgt
     2161 agttggcttg caatcctgct gttcccgtat ctgcgggtat gaacgatttt aaagtcctgg
     2221 ctggataaac aggtggtgct gtattcggtg ctctggcagg aggaggtcac tctacaccta
     2281 acaatgcgag agagccgttg tgacaggcag tgtatgagca agcaacggtg atttcctcca
     2341 gttttactgg agaaacggat gattaatatg ttaatcatcg ttctcagagc tgtggtcgcc
     2401 gttgcaaacg cgctgattgc agttctggaa ctgatccgcc aattcatcga ttgatgacaa
     2461 cggaaacgta actaagggca ggaagtgaac cgcttcctgc cctttaacaa aaaggaggat
     2521 ttatggattt tatgagcatt ttggggcgct gtttacttct tcctttccct gttgcgatgt
     2581 ttgtcggttg cctgtttcct ggcatcgatg atcgcttatc cggaatgctt atgagtgttg
     2641 ctgtgggatg tttatcgtgg tatgtcacca gaccgaagaa ccgacagaca aaggccgcgt
     2701 aagtggcctt taattgggat accctttagt tacaacattc taatagctca ttccatcctc
     2761 cgctcatcca gcaaacataa cctccctgcc cctccccact acagaaagtg gcgcgccccg
     2821 cccgtacggg cggaatctaa tcgcttaatt ttgaatgttg taactaaaca tactcattgc
     2881 tgtattgcca caaggtttcg cagcaaggga ggataccgaa agtaacgctg tcacttttgc
     2941 tttcaagtga ccaaccaacg ggtacatcac actgacatac aataatgtat ttcttcatga
     3001 tgtacatcat tgtaattcat tgtgacatac actatagtat gtccatgtga catacgcatg
     3061 cgtacatcac atagaaatac acatgagtaa atcactgtga catacaaggg gtactatgat
     3121 tatcgtaatc ggtggtgata aaggcggtac aggtaaatca catctggcaa ccaacttaac
     3181 tgtttgcctc tcacaacagg gaaagagaac ggggcttgtt gaaacagacc tgaatggctc
     3241 gaccaaaaaa tggaataaac gcagagaaca ggccggatta ccgcccgtcg cattaaatga
     3301 agcctatggc gacatcagtg ccaaaataac aaaaatggca gatgtagcag aaatcctcat
     3361 tatagatact gccggatatg acagcacgga gttcagaact gcactaaaag ttgcagacat
     3421 tgtgattgtc ccgatcgacc cgcttgccca ggtggaagca gacagtcttc agactgtgac
     3481 aaaaattgtc agggatgcgc aaaaaataaa tcccaggctg gctgcacatg tgctcctgta
     3541 taaatgccag ccaaatacgt tcagtgaaca acaagaatta agagactctc tcaacagcca
     3601 tgattactgg cttaaaccaa tgaaaagcac ggtttctttt ctccgggcct ttgtaagagc
     3661 aatgaatcag ggaatggggg ttcacgagtt aaaaagtaat gttagcggtg ccagccaggc
     3721 aaaagcacaa atcgaactct tgctgaaaga actggaactg taaatcatag tgacatacac
     3781 taatgtacat catcatgata tacattagtg tgaaacaatc agattagaag gtacatcatg
     3841 gcaaagctgg aactaccaga actagaacaa aaccaggaag tgaacgccac aaaatttgtt
     3901 caggacgcag gaaaacgccc cacagagaac aaaacaaaac tggcttcatt ccgcataccg
     3961 aatgaattgc ttgaattcat tgataacgaa tcgaaaagac tgcatcgtcc caagacaaaa
     4021 ataatcaaag cagcattact ggcttatcag gatctggacg aaaacgaact cattaatttg
     4081 tggttcagag ctgacagaaa tgattaatca tagcaagtgg cccaataaac tctttatcat
     4141 tttcttttag atacttatct gaatgtacta acttcatcac ttttaaatgt agttgtgatt
     4201 catttttagt tactcttgca ataaaatacc cttgtacagt tgttgcacgg gtatttagga
     4261 gcactagatg agccttatcg atttaagttt atcaggatta tcagaaccag gaacaaaact
     4321 tattgaaaaa taagtgatgc tattggtgtg ctttatgaac ctacaagaat caggaaaaaa
     4381 gcgaaggctg aagctgaagc taaacgcaca gagctaattt ctaggttaga gcttgaggga
     4441 atagaaaaac gggcagttga gcgttttctc aaacgtgaaa cgaaacgaca ggaaaacatt
     4501 gaaaatataa caatgcaagc agcacaaagt ctatctgaga gtgataatgt ttctgatatt
     4561 gacgaagatt ggatagaggc tttcttcagg gagtgtgagg atattagtga cgaacaaatg
     4621 caaatgcttt ggggaagaat tttatccgaa gaagcaaagt caaaaggttc gtttagtcgt
     4681 agaaccttaa aactattatc cactataagc aaagaagaag cgaaccttat tacttatttt
     4741 ggaaagtttg tttggcaggc aaacaaactc actccaattt tatttaccga tgagaatgga
     4801 gatactgaag gtataacttt cgataaactt tcggttttag actccttagg cgttattcaa
     4861 caaggcattg gttatagttt aacctcttga ttgttcaccc ttcttaaaaa acacccacgc
     4921 aagccctgcc gacatcgccc acgcaagcat catcgacacc accgtatggc tcaaaaaatg
     4981 atcgccaata atcatcttat agcagcccat cgcccagccc aatgccatca ccacgatgat
     5041 gatcgcacca cgacggcggc gcaaacttgg cgcaaacgca aaggcaaaca gcgcaaatcc
     5101 gctactggca tgcgccgcag gaaagcactt atcaggaatg gtgttacgca tactatcaag
     5161 catcggcaaa tacggcagcg taccatcaaa aatcgtcaaa tgcacagggc agaccacatg
     5221 agtatatgcc ttcaatgacg cgacaactgt cggcactagg atcaaagtca gcaccagata
     5281 cgcaagctca cgcacgcgaa attttgtcac tgggacaagc cacttggcag tgatagcatt
     5341 gccctttttc tcatgataag cacggcaaat ggtcgcaacc agcaagtaga tcagcatcgc
     5401 catcagcagc ttttttagtc cagaatacag tagcaaatct ggcaaaaaag cttgcttggc
     5461 aaccatccaa tgccccatac ccagataaaa ccaatcagcg accatcagat caatctgact
     5521 gtgctcaagg gtcagcgtgg caacgatcgc catgacaaga gcgatactca tctcagcaag
     5581 taggcgttta tttgataaat acggcataac aaaccccacc ccaccgccca taatacgaat
     5641 ggagtgtgcg gtgggtttgg aaaaaataca gggagaaatc agcggatgaa tgcggtgcgg
     5701 tctttgactt tgtccgcggt gacatcaaac agctttaata atgtcggcgt gatcgcgtca
     5761 tgggtcagga cggtatcggt tgccattggc gtgatgccag tttgcttatc cgtccagaaa
     5821 aatgcaggca cactgcgctg ttcttttggt gcaaaggcat ttggcatacc atgtagatag
     5881 acaccgttct cacccagact ttcgccatga tcgctgacat acagcattga gacatcatag
     5941 gcattgctgt gcgtctgcag ccactggata ctttgagcga tgaaatcatc ggtggcaagc
     6001 aaggcattgt cataagcatt gatcaaggac tgatgttcgc acttggcaag ctcattacct
     6061 tcacacactg gcgtgaattt ggcaaacttt tcatcatatc gcttaaaata cgcaggcccg
     6121 tgattgccca tttggtgcag catgatcagc atatctttgc cgttattggc agcgacaaag
     6181 tcatctaagc caacgagcat accgacatcg cggcattcgt tataaggatt ggtgttgcag
     6241 atggcgttgt tggtcgcgga tttataatcg gcaaattgcg cttttggcag cttatccatc
     6301 acgccttttg agtccgaatt attatcacgc cacaagatac ttacgcccaa gcgatccagc
     6361 gtatccagca cattttcttg gtatttggcg gtatcgacat catactcatc cgcgcccaga
     6421 tagctgaaca tacacggcac agaatacgcc gtcgatgtgc cgcacgatgt gacattgcta
     6481 aaattggtca cgccatcgat cttggcaagc tgtgggaaag tatcgcgctc atagccattg
     6541 aagctgacat gatcggcgcg tgccgtctca ccgacgacga acaccactag gcgtggctta
     6601 cgcatatcag gcttggttgc ttgtaccgcg tctttggcgt gataaatggt atcttttggc
     6661 gcactggctt ttttatactc aatactggca agcttaccca ccgagtagat tggcatgatc
     6721 ggattgacat agctacgcag cggcttatgc acgcgaaaga aactggcata atgactgctg
     6781 aacgccacca caggcagtaa aatcagcgca agacttgcca cgatcaagcc caatcggcgc
     6841 atcaaaccct tgccccaagt cggataatcc accttaacaa aagccacaag caaacttggt
     6901 agcacaccca aaccaatgat acgcatgata aacgctgcgt ttaatagatc cttggtctcg
     6961 gcttggtcgg tctgtagggc attttggagc atggtcgtat catagaccgt gccataagtg
     7021 tcagtaaaat aactggtcac cgcgcccatg attaatagca aaatcaacac aggctttagc
     7081 acatagcgat acgatgataa cagcgtggtg atcagtagca tcgcgccaaa gagcacgaca
     7141 gcgatcgtca gcacaaagcc gagattgtcc gcgatgggat aggtttggct gattttatca
     7201 aaaaaggtaa gattggcggt cgcggtcaag aaaacggcaa cactcgccac aagaacaaac
     7261 ggactgaccg agcgtcgata ccacacagaa gtatgctgca tcatgagaaa ctactcaaaa
     7321 aataaacggt gggataattg cggcaattat actgcaattt tttaagaaat ccagtacaat
     7381 ttatctgata taaaaaatta tgcgatacag aaatatttca gaaattttat taggcaatca
     7441 ttgcgcaatc ccatactgaa tatacacttg agagtattta taatttgtat ctttaaaagt
     7501 aaaaacggtc gtatcggtta ttacggaacg gttttttcag ttgagtttca aagcgatgat
     7561 tcatcaacct ggaaactacc aataggaacg gctttactta cgcctatcgg tcaagaattg
     7621 atgaaaatat gcggttccac tccagatatt gcgtatttaa ataaattcct caacaaaata
     7681 aatgttgaag gaagccaggt aaaactatca attattaata tgtaaagagg tcgagttacc
     7741 tgtctgagtt ccactaacca taattaaaag cgaccgcaaa aactgcccag tgaaaactgt
     7801 gttgccagta atcacaaatg cagcaagtac taataaagag cctgttaagc ccgcaaatat
     7861 gtgggcttat ttttaattac tcttcatcat cccgcaggaa ctgacaaaaa tcttcgctcc
     7921 ccatcatatc gacagtgttt ttaaattcga aaaaagaaat tcctgtcata gcacacacgc
     7981 gctggataat cagttttttc ttttgctgtc tgacggttgc ggtttcacca aactggataa
     8041 cagccaggac tgtttcatca tatgatttca ggacaaaatc acaggttata ttctgcactt
     8101 cacggattaa atcttttaca gcttcctcgc taccatgagg acgaacaaat tcaatgagcc
     8161 gtattttggg aaaaacggaa taatcaggta taatattacg tgaaagaatg cctaaaaact
     8221 ctgattcatt atttgagagt aagggtactt tagtaaaaca atcaacctcc ccaatggctg
     8281 taaaagcatt ggttgtcaaa gctggattgt tcttaataaa atcagagaat acattttcag
     8341 ctgatggcaa aacaacagca gaattatgtt gttcatctcg ttttttatta cggttaaata
     8401 tcatttcata ttccttttaa aagagcctgc ggcaggcaca ggcaaaaaca tcgtttttgg
     8461 acaatctgat tcaaatgtta acatttgaca tcggattgtc tatcctgcat tgttctttac
     8521 tgtctgtaag atcggcgctc attcttccgg cgttctcccg ataccaaaaa gacggaacgc
     8581 aaaacggctt tcgatccacc attcaaaaat ctgctctgcg caaccacaaa cagttaaggc
     8641 gatccatgca gcaagaacaa cgtaactact gacatctgca cccatgtacc aggcgatagt
     8701 taaacccatc actgcgatac cgcctaaaaa ctgcaacaag aaacgaaatc ccgcaagaat
     8761 ccccaatgga ataacaacaa ccagataaag ggaagcagcc agaaggtatc tgacaggtgt
     8821 cagcagataa aagaacctgg atattttctt tttgtcagaa taaacggcat catttgcaac
     8881 atcggttgaa tgatcattca tgctgtccct gattctttga aaatctacga tattatcctt
     8941 catattgtta tgacctcaat tttcaggtgg gtacatttta tcaaacatat tagtaaactc
     9001 tgagtcttcc ctggtatcgc cctcataacc aattgtataa gagaacttta atttataaac
     9061 ttttctccca attttttctg aaactacgaa acttaagttc tttacttccg tatgtttcat
     9121 gatttctttt actgatttat taagaacatc tcttttaaaa gcaggataat ctggatactt
     9181 ataatccttc accccccgcc cctattgtat aaagattcaa ttcatcttta agttcatcta
     9241 ttgtcatttc aaaactattc gcgcgagaat tattactata tattttacga atgagttgat
     9301 atagtgatgc agcattaaca cttgtcagtc gaacaacaga taataaaact tgcgttgtat
     9361 aacgtttttc ttcaccaata agtttacata aaaatctttt cgcttctttc gtaaacttga
     9421 tccccactct accttcattc ctgtaataag tagaaaaaac agtcagactc aaattcattg
     9481 aatcaggtac attactttta gtgaacttaa atcccaaatc actactcagt tctaatattt
     9541 catcatgttt cagcttaaga agcgtcgtat ctaatatatt agagccatcc ctcaaagcaa
     9601 gataagccgc atcaggctta acctgaaccc atttaatgta atcggcaact gtcacataaa
     9661 atatgtgatc atcatcgaat tcatttttag agtttatctg gcacatggct aaaaataaga
     9721 cttttttagc agccataggc aatgttgaca gcgttgaatt caattcattt cgatgtctca
     9781 cttttgttaa gcgagaaagg gaagtcttat ttgtcgtcat tctcattgtt ccaacactct
     9841 tgataatcag actttaacac cagaaacatg atattacaac acaatcaata tcatgtttaa
     9901 ccgagtatct tctcatgttt catatctgtg atttatctca caaaggtaat ccatgctcaa
     9961 aatccacact ggattcaagg cagattaaca acagattcaa aatagattca ccagaaagaa
    10021 caacgaatta gtattcttat gacacatttt gtggatatca ccgaggaagc tctcatgttt
    10081 aaccgaggaa gctctcatgt ttaaccgagg aagctctcat gtttaaccga ggaagctctc
    10141 atgtttaacc gaggaagtta tcatgtttaa ccgaggaagc tctcatgttt agacaaaaaa
    10201 cacgcttaaa atcaataaat tagagctact ctaagttttt aagtttttaa gaaaaacaag
    10261 aaaagataag gcttttaatg cgtgcgaata ttcaggaact gtggataact caacaaaacc
    10321 agcaacgatg atggttcctt accataaatc tgtcccccga tgattattac ccgcaagcta
    10381 aaacaaacat catcaatcat taaaactcat aactttcaat aacataaaat catcaaaaaa
    10441 atatttgatg ccttatgtat ctcaattttc aagaccataa atttgtccct agttaacttt
    10501 aacttattga aataaatata atattcgtgc gtactgatcc taatgtcaca tcgcaaaaat
    10561 tccgcttcct cgctcactca gtcgctacgc tcctgccgtt cggctgcggc gagcggtatc
    10621 tcctttctca aaaccagaga gattcagatc atatgatccg ttatttgatc cttttggatc
    10681 ttccactaag aagccctgaa tcgcgctctg ccgcttcgtt cgatacaacc atgaggaaaa
    10741 ccatgcgaaa tgaaaaaaat cgcttaaaat gcgattcaga gcgttttagg gaggttctgt
    10801 tagttctcct gcattgcgcc cgtagttcgc taacgctcac acgcgcagta cagcgccccg
    10861 ccatgctgca atgcaccagg gcggggtaaa ctcgcttgcg ctcgcgctaa ctgcggcatt
    10921 ctgcggcgca aatcagcata atcatggcct gctggtcagt tgggctttgc agggtgaagg
    10981 gatggcctgt gcaccctggt acgttcgtca gcggctgcgc cgcgcttcgg ggcgatgtgg
    11041 ctcctgtgct gccctggtat tttcgttcgc cccttccatc cgcttacgcg gattaaaaaa
    11101 cgtgataaca atcacttatc gagtaaaaaa acgggagaaa acttgcaaat acgacttaaa
    11161 ggtcgtatta ttgtttcatc gaaaggggaa tggcccctct cacaatagcc cagcagggca
    11221 ggagattaaa aaaatgaata tccaggaagc attaaacgtt tttggattat ccggcgaatt
    11281 aactgaaaaa gatatcaaag cagcatacag aaaagccgct ttaaaatatc atccagatcg
    11341 taacccgtta ggggctgaac tgatgaaagc ggtaaatgca gcttttgatg tattgatggc
    11401 aaatattgat aaaataaatc agttccagag cactgatgaa catgcacgat ataattacgg
    11461 tgatgacctg gaaaaagtat taaacgttct ttctggttta tctggtctgg tatttgaagt
    11521 gataggtaac tgggtctgga ttagtggaga aaccattaca cataaggaaa ctttaaaaga
    11581 aatcgggtgt aaatgggcgg caaagaaaaa acaatggttt tatcgtccag acgaacataa
    11641 aagttactgg aatcgtgaag aacacacgat agaagaaatc cgcgcaaaat acggtacaac
    11701 cggacagcgc agggcgacag ggtggcaacg cgtggaaacc agagcgtaac cagaacgggg
    11761 gcgagaagcc cccgatatta tagccagccc gtcttttggg gcatcgaacc caaaaagacg
    11821 ggaacagcag ccacgtagca aaaagggaaa cagatgaact ctttttttga acaatatcac
    11881 cctgtctttg aagttgtctg ccgtatcctg gggaacggct ggcgcgtgaa caaacttgat
    11941 gattgttcgt ctcgtataaa actgacgtca ccgcagttta aaaattactc tgtgcatatt
    12001 cggatggaaa aagaccgctt ttctgtggtg gggagtgtgg atagtcgttc ctggcgtagt
    12061 ccgcatcatg tttgcacgtt atccagaaaa cggaatcccg ttgatattgc agccgatatc
    12121 gagcgaaaaa ttctggtaaa tgcttcgcag gaggtgttac aggcgattga gtatgagaaa
    12181 caccaggtgg aaaaaaagga cgaaattctg atcctgaaag gtatgttatc gcaacttgtc
    12241 cagcttgaaa gctggtatgg ggcattgaca ggctttaaag ctgaaaacgg attgaacggt
    12301 aaagtcaccg aacagggcga cagttatgat ttacagattc ggggcttgag tatagatcaa
    12361 cttgttaaaa ttacagggta tttgaaacag ttatgagaaa aaataaaggt gatgtgactt
    12421 attttcttga aaaagaaggt gacaattaca ggcttacaaa aaggataaaa gccagaacaa
    12481 atgttaaaat cgggaacaaa actacgaaaa ttacattgta tgatgctgta ctgaatgaga
    12541 atgaattaca acatattgat tttacgtgtg ccggattaag ggaagacgat gagacgccag
    12601 ttaagaattt aattaaggag tttatgttaa atgaaacccg ataatacacc tgaaaatgta
    12661 aaaaaattac gtttaaaagc aggattaaca caaaaggaat gcagtcatat ttatggtgtt
    12721 gggctaagaa cctggcagaa aaaagaggaa gttaatactc aaaacagtca aagtctgtca
    12781 ctggttgagt ttgagtttct tttgttactt gcaggagaac atcctgaata cgtgctctgc
    12841 aaaagggagt caaaataaaa tgacctgtga tggttttata ttagtacctg gagttgcgct
    12901 cgtagctcgc tgacgctcac acgcgcagta cagcgccccg ccatgctgca atgcaccagg
    12961 gcggggtaaa ctcgcttgcg ctcgcgctaa ctgcggcatt ctgcggcgca aatcagcata
    13021 atcatggcct gctggtcagt tgggctttgc agggtgaagg gatggcctgt gcaccctggt
    13081 acgttcgtca gcggctgcgc cgcgcttcgg ggcgatgtgg ctcctgtgct gccctggtat
    13141 tttcgttcgc cccttccatc cgcttacgcg gattaaaaaa cgtgataaca atcacttatc
    13201 gagtaaaaaa acgggagaaa acttgcaaat acgacttaaa ggtcgtatta ttgtttcatc
    13261 gaaaggggaa tggcccctct cacaatagcc cagcagggca ggagatttaa aatgaaatgc
    13321 tcatctgttt ttacttcaac cactaatcat gttttcacat tcgaacgagt aacgctttgc
    13381 actattatcc ttatgcataa ggatactgga caacagtatg ttgtcatatt tactgataac
    13441 aataaaattc gtgactataa agccggaatt gttcctcagt ttggcgaact taagcagagt
    13501 gatgttgatt tagtcctttt ctacagggac gaatatgaaa aatattttga ttcattaaaa
    13561 gatggcgatg aatgcttgag ttttaaagat tttattgagt gtctttgtta agcattatga
    13621 atgcaggggc atccctgcat tttctggaaa tttcaatatt gattctgaaa ttgtctatta
    13681 acatcaatgc aagggaaatt catgaaaacg ttaaaacaag ccgcaatgca gtttgcatct
    13741 gatctgcgta ataatcgctg ttttaaagct gcttataatg atgctctgtt agagcttgat
    13801 cgggaagatt taaacgccat tgtacaatgc acatttcttt ttgagccaaa acgaacatta
    13861 gccgaacttg ataaattaat taaaaagata gaagtagaag aagattatga gttttgtgta
    13921 tcccttgata aaggtaaagg attacacgaa gtcagaacat ttaaaagtga gcgtgaggcg
    13981 ttggatgctt atcgcatttt gactctttac ggatacacag taactataga aaagaaggag
    14041 ggtaatgact gactattcaa ggtgtgatca ggttgttcca ccaacctgat cacgttatcg
    14101 acaatcaaaa ctgaatgagg tttttaaatg tcaacgcggc agatcgtaca gcttgctgat
    14161 tcccttgtca aaggctggga aaccagaatt ccggcaatga aatttagcga atgggatcaa
    14221 ttccggtggt ggttaaacta cttgcaaggg tatgaaatgt tttaaataaa aaaaggggct
    14281 ttctgcccct ttgtattttt tgacaaaaat gccatgtgta actataatta gttgcatatc
    14341 tataggggat ggatttatgg ggaaaacaga taagctactg gcaaagtttt taaacagtaa
    14401 aaaaacgttt gaatgggatg aactggtcgt tttgttttcc tctttgggat atgtcaaaaa
    14461 ggaaatgcag gggtcaagag tgcggttttt caatgctgaa atcaatcaca ccatattaat
    14521 gcatcgtcca catccggaaa gttatatcaa aggtggtacg ctgaaagcaa ttaaacagaa
    14581 tctgaaagag gctggattat tatgaaacat ttaaaatata aaggatattt aggcacggtt
    14641 gaacccgatt ttgaaaataa tgtcctgtat ggaaaactgg cgtttattcg ggacctggta
    14701 acttatgagg cttctacatt agctgaactg gaacaggagt ttaaaacatc tgttgatctg
    14761 tatttacagt cttgtgtgga ggatggaaag gaacctgata ccccgtttaa aggcgtgttt
    14821 aacgtcaggc ttgatccaga actgcatcgt cgggtagcag aaatggcgat ggaagaagat
    14881 ttatcgttga atgcctttgt taataaggct ctggaaaaag aagtcagcaa tcatcgcgca
    14941 ggggcttaat tgcccttgtt tttatgccct gtaagggcat gggaggcgct ttgcgccgga
    15001 agccccgcag cgcagcgagg acttaaaaag cgttacggct tcagccgtaa caattcccag
    15061 ccctgccagg cctgtttttt ctttcacaaa tctttcagct atacgtttgc ctgatggtcg
    15121 aagacgaaag aatctttcag caacgaaatc tggacatatg cagcgacgat tttatagcca
    15181 ggcacagtgc cacatatggt acaatcaatg caggatagac aatccgatgt caaatgttaa
    15241 catttgaatc agattgtcca aaaacgatgt ttttgcctgt gcctgccgca ggctctgttg
    15301 gggtgactta tgaagatgat agcgttcagg ctaagtgatg atgagttaaa atttgcagaa
    15361 cataacgcta ttttaagtgg atttaccagt atcaatgctt ttgctaagca taacgtgctt
    15421 aatattgaaa ccaagcctgt taacatccca gttaataatg aaccagcaaa gctggtatca
    15481 gtgcgtcttt accctcatga aatagaactt gttaaacgta atgctgctct tcacggcatg
    15541 agcatgagca gagaaattgc tattcgtgtg cgtcagtctt tgttaaagag tgaagtctgt
    15601 ctttaccctg atgaagttaa ggaacttaaa aaactatcaa ctgctgtaga tcgtgttggt
    15661 cgcaacattc attttatcat aaaaggtgaa agattctgta cggttaacga tccagatttc
    15721 agaaaagacg ttattgaagt gattgaactg tgtaagcaaa ttgattcaaa acttgaaacg
    15781 ttaaccaaga gtgttgttaa cagatttggg tgatttatgg gtgtgtatgt agaacaggaa
    15841 taccgtatta aacgcgctaa agggactggg cgtgatccga aatctcctaa gttatcggga
    15901 agacatatac atgccagtaa atcggctttt aatcataaag tcagacatgg tgcggacaag
    15961 aaagcatata cctggacacc tacaaaagaa gtcactttta aaatcactgg ctcaggtaaa
    16021 acagccgcag gcatcaaaaa tggtattgat tacattaccc gtaatggtga acttgaggct
    16081 tactgttatg atggaaaagg ttcagagcaa acagggaaag gagaagactt taatagggag
    16141 tttacttcaa ctttatctaa aggaaatgat tactccagga catatcgtgg agaaaacatc
    16201 gatcatgtga aaaacatggt cttttcacca ccaccagaag ctggagtaag cagggaagac
    16261 gctctgaaag ctacggtaga atttcttaaa gagacttatc caaaccatgc tttcgttgcc
    16321 gtataccatg atgataaaga agatcatcct catgtacatg ttaatattaa acttcgtgat
    16381 gaagaaacag gaagaagatt aagacttact aaatctgaaa ccaggaagtt cagaaacggt
    16441 tttcatagaa aactgaaagg tatgggatat gatgttaccg ctacctggaa aaaagatccc
    16501 gaacgtaaac gggagattga gcgattacag gctgaaaatc cgaaaagact ccggaatgtt
    16561 tacaaggtgg tggattttgg ggagacttca tatcagaata aggcagggga aaaacgaaca
    16621 cctttcctca cttatgaaac tttaaaaggt ggaaaacagg ttacgatttg gggtaaagac
    16681 ctgaaaaatc atttcgagtc tgaaaagctc cagccaggaa cgcttatcaa agtaaaaaaa
    16741 ctggctccta cgcttgtacg tagtccaatg tttaatgatg atggaactgt tgcaggctac
    16801 agggaaacgc atcgcaataa ctggcagatt gaaaatattg cccttgagcg gaacagagaa
    16861 cgtcaggttc atgagcgtga aaccaggcag ccggaagaga gcgacgttaa aaagcagcta
    16921 tccagaaaac atgagcaagg tcacaatatc gggtttgctc ttgaacacgg gtttacaaag
    16981 gattcagaag aacataaaaa actaagaata cagcaagaga ggaactggaa aggcctggga
    17041 ttttaatttg attttggcgc aggtgaacaa agcggctact ttgctcacct gctgatcaca
    17101 acaacctacg agggaggtta tcatgactga gcatgatgct atctgcattt ctgcacttca
    17161 tcaaattttt agtgatgaag aacatttgag tgagcaacaa aaagacatta ttctgatgta
    17221 cgcttatggc tataccctga atgaaattgc tgatttcaaa ggactaaagc cttcaactgt
    17281 cagaaaatat ctcgattctg taagagctga actgggaggt gtctcgttgg cagggatcag
    17341 aacactggta ctcattcgga ctaatgccct tctcgtgtca agtctttcca ggatcagtga
    17401 gagggggaat ttatgaaaaa atatctgctt tttgctttgc cgttcttcgt tgttggttgt
    17461 agtgaagaag taaaaagtgt ggattggtgg gggcagcatc ttacggaagc taaacaaaag
    17521 caggcagagt gtgagaagtc tggctctgat tctcagaact gtaagaatgt taaacaagca
    17581 ttgtttattc agtctcagaa ggatgctcca gtccctacat tcgattaact aatgtttcaa
    17641 tcatactaga gcgcccatat gggcgctttt ttttgcatga tcacacgaat cataatatga
    17701 ccattttgtc aatgttattt gatcgtattg ttgagcattg ttattttgcg aatcatgttc
    17761 gcatctaaaa caaatccaaa acacacttat agtggattga ttaaatgaag gagaaatcag
    17821 ataagtcatc ggaaaaaggg gtttatgtca cgataaaact cgatcccagg ttgaatgcat
    17881 ttatcgaaga gaaaacgaaa acatctttgc ttagtaagag gaagcaaatt atttacttat
    17941 taatgcagag tatgcgtatt gatggatata tggagcgtta gctatggcgt ctttattccc
    18001 agccttgttg ctgtgtgcgg cgtcagttca tccggatacg ataaatgata ttgcacgggt
    18061 cgagagtggc ttcaatcctt atgctgtggc tgaaattatt cctgaaaggg aacgcggtag
    18121 ctatggcaaa agtgttatca gtcatatgcc caaaagtaag gaggaagctc taacagttat
    18181 cagagaaatt gaaaacagaa aaagacgtta ttctgtcgga ttgatgcaga ttaccagcag
    18241 taatttttct ttttattcca cgtccgcaga aaaactcctt gattcgtgtg aaaacttgtc
    18301 tgttttcgaa aagattatcg tggattgtta taaacgaggg aggagcctgg agaatgcgct
    18361 tagttgttac tatacaggaa attttagtaa cggtaagcga aaagaaaaag aatttaataa
    18421 tacaagttat gttgagcgaa ttggttatac agggaacgaa aaaaaatatg ttgtaccagg
    18481 tacaagaagc aacgggggag aacagcgaaa aaatcgttca cacaatgcgt cagttatctg
    18541 gcccgaaacc attctgaaat ctgcttttgt tgataactca catccaacaa aagttattaa
    18601 ttaacaggac ttataaaatg tcatttaaga aatcagtatg taatcgtatc agttcatctg
    18661 tcactgctgt aatgcagcgt aaaaataagg tagttatggc agtcgccggg gcaacagttg
    18721 catcaccggc ctttgcggat ggattttcaa aagcggaaac actgctggaa aaggttaaaa
    18781 cagggcttag tggcctttca ctggtcacgg tgactattgc ctgtctgtgg gtcggctaca
    18841 aggttctgtt tggtggaagc acgattcgtg aatgctcacc tatcatcatc ggggcaattg
    18901 ttatcgccag tgcggctgaa gttgcatcaa tgatggttaa ctaataaagc ggggacgata
    18961 gtatgtctac actttataaa gcgatgacac gccctgctat gtatgtgggt gttcctgtcg
    19021 tccctcttac tgtggttgca ggggcgttat ttctggcggg ggtttatatc agcaagctga
    19081 tctggctggc tattcctgtc gcggtttttg ttctcagaat gatcactaaa caggacgacc
    19141 acatttttaa cctttacttt cttaagctga aaatgctcgg aaactcagtg tgtaatcgtt
    19201 tttttggcgc acgagcgttc ctctccggac aatatgaagc tgttgaaatt gatgagtttg
    19261 ttaatgccat gaaactgaat gagcgaatca ctactggtaa atatataccc tattcaagcc
    19321 atgttgataa aaatattgtc aaaacaaaga acggtgatta tgtagcgaca tggcaactga
    19381 tggggattaa ctttgagtca atctctgcgg agatgttaga aactattgac tcacaggttg
    19441 ccactcttgt tcgttcattt tccggactgc ccgtttcatt ttataaccat tcatgcaggg
    19501 cgagttttta tgatgccttt accacaaaat caggtaataa atatgctgat ataatatcag
    19561 attgttacta tggttcgatg aagaaaaata aattcaaggg gaacactctt tactttacgc
    19621 tgatctacag accagatggg cgtgtagaaa aactggaaaa acgcaaaaaa agtattaaag
    19681 aaaagaaaga tgatattaac attcatgtga agagaatgaa tgaaatgatt aatacattct
    19741 ctggcgctct tgataaattt acctgtaaac ttcttggtat gtatgaggag aacggaaagg
    19801 tattttcttc tcaactgtca ttctataatt atcttctgac agggaagttg caaaaaatca
    19861 gagtcactga ttctccggtg tataacgttc ttggtggagt ggatgtattt tttaatcatg
    19921 ataccggaca gatatgccgc attgatggaa ataaattctt tcgttctatt gaaattaaag
    19981 atttctgtag tgagactgca tccggtgttt ttgatgtgct ccagtattct gatgctgact
    20041 atattattac gcattcatat acatccatga gcaaatcaga agcattgagt accattaaac
    20101 gtgcggaaaa acagttaaag agtacagaag atgatgcggt tactcaattg caggaactgg
    20161 aaaaggcaaa aaatgatatt gtgtccggtg atatatcctt tggttactac catttcacgc
    20221 taatggtaat ggcggacagt atcagggagc ttgacgaatc tgtaagtaaa attacggcag
    20281 actttactga cctgggcatt attccggcat tgtcaaccat gtcattgcca gcggcatatt
    20341 ttgcccaact tccggcggtt tttcatttaa ggccgcgttt atctccggta tcgaatgtaa
    20401 attttgttga actggcatca ttccataatt tctaccaggg gaaacgcgat aaaaactgct
    20461 ggacagaagc ggttgctatt ctcaaaacac caagcaaaca ggcgtattat ctgaatttac
    20521 ataactcagt actgtttaaa gatgaaacag gtgaaaagaa tcttgctaat actaaagtta
    20581 taggaacggc gggttcaggt aagacaatgt ttctgtcata tcttgcctgt tcattacaga
    20641 aatacaataa ccccgaaact tttgctgatt ctgcaaaaaa taagaagtta acgtgtgtct
    20701 ttcttgataa ggacagaggg gctgaattat gtatccgaat gcttggtggg gaatattaca
    20761 ccgtaaaaag cggtgagccg acaggatgga atccttttgc tctggaggca acaaaacgta
    20821 accgtatttt tgtcaagcaa ctgatggaga ttctgtgtac cagaaatggt gaaagattat
    20881 cgacaagaga aagattgctt attagcgaaa gtgttgatgc tgtgatggat tttcctcctg
    20941 gcgaaatgcg ggaatatggc attaccagaa tgcttgagca tcttatgcag agagatgatc
    21001 gggatgagca ggagaacggg attatccttc gtttgtccca atgggctaat ggtcaggctc
    21061 atggctgggt ttttgataat gctaaagaca cattcaatat tcagcatgtc aataattttg
    21121 gcattgatgg caccgagttt cttgatgatc cgatggtatg tgcaccaatt actttctatc
    21181 tgctgtatcg cattacgcag cttctggacg gtcggcgtct tgttatcttc ctggatgagt
    21241 tctggaaatg gctacaggat gaagcattca gcgactttgt ctataacaag ctgaaaacaa
    21301 ttcgtaagct gaacgggctg gttattccgg caactcagtc tccggatgaa atactgaaga
    21361 ataagatttc acgggctgtg gttgaagtat gcagcaccag tatttatctg gctaaccctg
    21421 atgccgatta caatgattat gtggaagggc ttaagctgac accagaagaa tttaatattg
    21481 ttaaaaatct tgatccaatg tcgagacagt tcctgattaa aaaaagcagt cttaaaaagg
    21541 gggatggtaa atcattttca gcacttgcga cactcgattt atcgggactt ggtggatatc
    21601 tgaaaatatt gtctgccagt gcagataatc tggaaatttt tgaaagtatt tatcatgaag
    21661 gaatggagcc tgatgactgg gttcctgaat atctcgaacg ggcaatctga caggtgaatt
    21721 tatgaaacgt gtaaaaacat tgatgctgat atcattattg acggcttcat tttatagtag
    21781 cgcaggaatt ccggttgcta ttgatgccag tccggaatgg gctgttgaag ccgcaagatg
    21841 gacagaacga ctcaaacaat ggtccgaaac tgcgcaacat tatcagagtc agattcaggc
    21901 atataaagac cagttagcca cggcaacagg tataaggaat attgcggcat tcacaaatga
    21961 actaagtaat ctacaatcag aactgacaaa tatttataag caggggaaca gttatatttc
    22021 tgattttacc agtaatcccg aaggtgcatt gagcagccag gctaaaaatc tgttcagcaa
    22081 gtatggagcc ttcgatatgt gtaatacggg ctatgaacgt aatgataatc tctgtaaagc
    22141 acggattgtg tcaacggctg ccagtattga acagggaaat gagatcaata agcagttatc
    22201 aagtgcaatg tctcagattc agagtttaag tagccgaatt gaggcttcaa aggatatcaa
    22261 agaatcccag gatttggcta acgcattaca ggcgcagtcg ttaaaaatgc aggcgataaa
    22321 aatgcagtat gatgtctgga ataataaaaa taaagcagat catgagatgt tggtcacaca
    22381 agaacaagag gcctttatta aacagcagaa agaagctgaa ccattaactt ttgattaaaa
    22441 ggtggatata tggctcaggg gtttttcgtt aaatataatt ctaccgttat ggattcggta
    22501 gataaaatca gctccagtta tcaaacacaa tttgctaatg atattatgtc gttagcgacg
    22561 gtatcggtta cgttatatgt actatggaaa ggatatcaaa tacttgccag taaaactcag
    22621 acgcccttgc aggatttagt atgggatcta tcaaaatttg caatcataat catgtttata
    22681 actaatgcgg atgggtattt aactgcggct actgatgcgt tgcaaggcat gaaagatggt
    22741 ttttctggag gggtgagtgt ctggcaaact ttagataact tatggaaaag tacgcaaaat
    22801 cttggtgcgg aaatatactc tttagataaa tcaacatatg ttaaagatca aggtgtagtt
    22861 ggtcagtttt taatatggac tggctcgctt attttaatgg ctgttagtgt ggttgttttt
    22921 ttaacagcag atgtaacgat gaaactcctg attattacag caccgatatt tatcttttgt
    22981 ctcatgtttg gttttattcg gagcatgttt aataattggt tacaatcgtt attctccagt
    23041 attctgacag ttctatttgc cagtttagtg attcggatag caatggattt tcaagggatg
    23101 atcctttccc atgctattcg tgctgcacaa acagggaatg taaatcttgt atctacaggt
    23161 gctatgggct ttatggctgg gtttttgggg gctttattgg ttcttatagc taaaggtttt
    23221 gctgtccagt tagcaggtgc aggtgttgaa ggtgctgttc agggcgcagc catgatgggg
    23281 ctgggtgctg ctggtatggc tactggtaag tctctgatgc ttggcggtcg tgctggttta
    23341 ggttttggct tagggatggc cggaagaacg ggcatgaatt ctttatcagg gaaagcaggg
    23401 aatctgatgg ggcgtggtgc gcgaacagcc gctgaatggg cgggtgaaaa gggatatcag
    23461 gcgctggctc cgacaggtgc tttggggatg aaggcgagaa gacttgcatc cctggaaaaa
    23521 gcacgagcga ggaacgccgc atgaaaataa tgaaacgttt tttttatgtg atgtccctga
    23581 actggatact ggtgttcgtt gataaacata tcacctccgg atggagcagg aagagaaagc
    23641 taataaccca gcttgttatt ttaatcacgg gaattacctt atttaaggtc ttaggtggaa
    23701 tcagtcagag ctggttgtga catgcttcat tattttgtca tgatacttta ttttgtccta
    23761 atccttcttt taggagtgtt tacctgcttc gcaggaataa gacttggttt agggcttgcg
    23821 gggaaatgga gaaagggtat ggatcttcgc tttttgcttc ttattggtgg gattcttttt
    23881 cttcatcttg gcctttatct cttaaaggtg ttcgtgaacg cttaataagg tgaatttatg
    23941 cgatgtgtga ttcttttgtt tttcctgttt cagatttccg gatgtaccac aaggaataac
    24001 cttccttctg atgtttccgg cgaactggaa cccattaacc acagccaggt aatcagttat
    24061 gagtgaaaaa atcgaaaaga agattgagac agctaaatcc ttcgaaagac aactctatgc
    24121 agaaaatgaa cggtctaaga aaaatgcatg gcgtgttgca gtggcagcat cattactgtc
    24181 cttatgtctt ggggctgcaa tttgtgttct tgtgccatta aaagaaaaag agcttgctat
    24241 tgtggctgtt ggcgaaaaaa caggccgtac agaactgatt actcaggtta aacaggaaaa
    24301 gatcctgcaa tctgaagcac ttgggcggta ttttgtaaac acgtatatta ctttacgtga
    24361 aggttataat tatccgtctc ttcagtatga ttatgagact gtacagctat atagctcgaa
    24421 tacagtaaag gacgattatc ttcgtctgta taacagcgat atggctcctg ataaaattta
    24481 tcataataac ggttcttacg ttgcggttga ggtcatctcc aatattattt ctgacgcaac
    24541 cgcgccagat aaactggcct ctgtgcgctt taaaaaaacg acgagaaact tcacgaccgg
    24601 acaggtttca gtttcatact ggacggctcg tgtgacatat cgttttgaac cagaaaagtc
    24661 ggttaaaagt tccagtcgtg agcttaatcc tctcggtttt actgtaacca gttaccagac
    24721 agatcgggaa gtcagggggg aatgatgaag aaattattta ttgctacatg tttattgctt
    24781 cctgggcttg tgtattcagc agcgactccg ttaccttctg gatttgatgc aaggatgcag
    24841 actgtgagtt ataacggtgc gaatacgacc gttatccggt caaagacagg atttctcaca
    24901 tcagttgttt ttgatgaagg tgaggctgtt atcagtgcaa aggctggttt tcctgccgga
    24961 tgggaaatca caaccgatga taatgttgtt tacatcaatc cgcgtcccgt tgttcaggaa
    25021 caggaaggcg atgaaggcga aaaactgaaa aaggttttcc agccaacaga aaaggaatgg
    25081 gatacgaatc tttttgtcag aacaacaaag cggatttaca gtctggatct aatccttctg
    25141 tcagaagaaa aacaagcgca acctgcttat gttgtacaat tccgctatcc atcagaaata
    25201 gcgaaaaaga atgcagaaga agtaaggctg gcaaaagaaa aacaggaaaa actcagacag
    25261 aagaaactga tttctgaaag ttttgaaaaa gccgatgcgc ctaaaaactg gaattatttc
    25321 atgcgagtca atgaaaaata tgacagtcgt cgtatcgccc ctgattttgc ttatgataat
    25381 ggcatattta cctttttagg ttttaactca gggaaagtat tcccagctcc atttgctgta
    25441 agagatggtc aggaacagac acttgctttt aatgtggaaa caaaaggcaa gtataaaatt
    25501 atggttatcc acaacgttaa tgacaaattt gttttacgct atggaaacag cgttgttggt
    25561 gttgtgaata aatctttcgg aaaagtatta accgaccaga ggaatacgtc ttctcctgcg
    25621 gtagaacgtg ttgaggtgaa taatgactga tatgaaaaaa acagatgatt tagttgatga
    25681 tgcgaatcag tcaaagctgg aaagtaaacc cgttcatgat atcggtgata tcaggaacaa
    25741 aaataatcgt atgcgttctg gctttctgtt tggtctgatg gctgtattag ttattggtat
    25801 ttttgcgctg aaaacatata aaaattattt tgcagatgac cagcagaaag catcagaatc
    25861 aacaggcgat accagcattt ctcaggtaag taaaatccgt actggtcttg gtcagaattt
    25921 tgaccctgtt gagaacaaag caattatcaa tccaggcgct actggttctg gtaatactgt
    25981 ttctgacggt cataaagaag tgccacagga ggggttcagg aaatatttgt caatacctgt
    26041 tgctggtcag ggagggagtc agactggcgc gagtggcagc agcaggacat cgcagacatc
    26101 agagccacag gaagaaagga aagaatcaaa agaaaatgtg cctggtaaat caggaatgaa
    26161 agtaactgcg attaatctcg atcctgatct ctatattgag gaaaacaggc ttataccgtg
    26221 tgctttaacc acacgctttg tttctgatgt tgcaggtcgt atcagttgtg tttttacaga
    26281 agatgtatgg agtgctaatc accacacaaa attactggaa cagggaacta aggcttttgg
    26341 tcgttaccag accggaacgc tgaatcatgg acagggcaga atgttcgtta tgtgggagca
    26401 gttgcggacg cctgataata aacgaatcga tatggtaaat acagcagcag ctggtcccct
    26461 gggagaagcg ggcattgatg gatggatcga ttctcacttc tgggagcgtt ttggtggttc
    26521 tcttatgctc agtatggttc aggatgtagc ggcggcggcg gcggataatg cacctggtaa
    26581 agatcgtaat gtggattata ccgaaaactc acgacaggca atggctgaaa tggctaaagt
    26641 cgcacttgag aattcgataa atattcctcc aacaatgtat aaaaaccagg gtgacataat
    26701 cactattatg gtcggggaag acattgattt ttctgatatc tatgagttaa aggtaaaata
    26761 gtatgagtgg cgttattcct gtcagcatta gcaataaatc gctcgatttt tataaaaatc
    26821 aagtattcca gtcttttctt gatattgaag ggctaacaga aattgctgtc aaccgtcctg
    26881 gtgaaatctg gacggaaatt aatggtgact ggacattcca taataataac agtgtgacct
    26941 ttgatttttg taaacgtttt tctcatacgc tggcatcatt tcggggagat gaaatcggcg
    27001 agaccaagcc attactttca gcaacactgg aatcaggaga acgtgtacag gtcgtttttc
    27061 ctcctgcatg tgagagaaat actatttcaa tcactatacg taaaccatcg acacggcaga
    27121 taacacataa agaatatgtg gcgaacggtt tttatgatta tgtccagtca ggaaaaaaac
    27181 acaggacata cgatgatgag cttcttgatt tattcagagc gagaaatatc gctgctttta
    27241 tggagcttgc cgtagcagca gggaaaacca ttgtatttgc cggagcaacg ggttccggta
    27301 aaacaactta tatgaagagt cttatcgatt tcataccatt gaatacacgg ctgattacga
    27361 ttgaagatgc agaggaaatc aaatttttta tccataaaaa ttatgtgcat cttttttacc
    27421 cttcggaatc cggcagtgat tccggctcta tcataacagc agcgaaatta atcaaatcct
    27481 gtttgaggat gaaacctgac agaattttac tggcggaaat taaaggtggc gatgcctggg
    27541 attttgtgaa agttgctggt tctggtcaca gtggaagcat gacgtccatt cacgcggcct
    27601 cggcaaaaga tgccatcatt cagatggtga caaaatgtta tcagaacaga gaatgtcaga
    27661 atcttccttt tgatgttctt cgtaaaatca ttatggacag tattgatatt gttgttcatg
    27721 taggcaggga tggtgttgtc aggcatatga gcgacatcta ttacaaaggg gctgaatgtg
    27781 aaaactttta ataagtcgca atctgttttt atattcgctg ttatgcttgt tgcggcatgg
    27841 tttgcaggtt catttatttt ctttgtgctt tacttcagcc agataaagaa tctgaaacca
    27901 ttgaaggctg tgttcagatc cattgatgcg tacaggatgg atatttttac agacagcctt
    27961 actttatctg ttgtgactac ggatatcaga gttttagcct ttgttgcact tggagcagga
    28021 tttgtcgtgt ctcttatcat ccctgttgcg gcgttgataa aactgaacga gaagaaagaa
    28081 aatattttcg gtgatgcgcg atttgcaaca attaatgata ttcgtgagtc taacagtttc
    28141 acgcttgacg gtgacgaaaa agacgggatt atcgttggta taaaagacaa gaaaatcata
    28201 cgctatgtgg gagcagcatt cagtgctatg ggagccggaa caagggctgg taaaggtgct
    28261 ggtatagtca tcactaatct tatgaagtac tggtggagtg ttattattct cgatccaaaa
    28321 agggagtgtt ttaatatcac cagtcttatc aggaaggtga ttttaggtca tgaggtttat
    28381 aaatttgatc cctttagttc ggtaacgcac cgctttaacc ctttgtatta tgtcagcatg
    28441 ggaacgagtg aaggttttaa tcagcttgaa aatctttcgt tgattattta cccctataag
    28501 acagatggtg cggatgctgg tagctatctt aataagacgg cgggtggtgt ttttaaatct
    28561 tatgctgtcg ctttatggtt tatgattaag aatgataagg ctggactaaa aacgcttgat
    28621 attgagcctg tcttctcaat gtctaaaatt aatcagcttt ttgagcgtgc agaacccgaa
    28681 catcttcttt cattcatgaa tgatattcgt tcagaattaa gggggaaaga caaaacgctt
    28741 gctgatattg gtgtcgctgg ccttaaggca ttcattgaga tggaggataa aacaaaagca
    28801 caactcaaaa gcaactttct taatggatta tcaccgtttg ctaaccccaa tgtggcaaat
    28861 gctactgatg gaaatgattt tgatttgcgg caggtgcgga aaaagcggat gacaatttat
    28921 ttctgtattt ctggtgataa tgccaggttg gctgaaaaaa taacaaatat tttctttcag
    28981 cttgctatac aggtgaatct tgaaaagatg ccaacggatg atccggaaat aaagcatgac
    29041 tgcctttttc tactggatga attcccgtca attggtgctg tagattacat caagagtaaa
    29101 tctggtctca ttgctggtta caagctgaaa ttgttgattg tttaccaggt cggctctcag
    29161 cttgaggaaa tctacagtta tgcaggcagt aaaacattac tggcaagtgc accctgcaaa
    29221 attgtttatt ccgcttctga tgttaaagat gcgcgggagt tatcagaagc gatggggaca
    29281 cgaacagtaa ctatcggttc gaaaagcaaa agtcgtagtc gtggaggaac atcgagatct
    29341 gaatcagaaa gccttattga gcgtccactg gtaacaacaa atgaactact tacactgaaa
    29401 tttagtgaag aaatcctggc aatgaaggga gaaaacccga ttcgttgtga aaaggcattc
    29461 tactatctca atgagtattt ctttggtgac tttgtgaagg ttgctccgga acttgcaaac
    29521 attttcccca ggaagaaagg aaagctggtt atgcctccac agaaagtatt tgaaaatgaa
    29581 atcgtcgcaa aagggtatct ggtagtaaaa gatgttcctg atctcgataa agcggcataa
    29641 aggagaacat gatgaagaag ttagtgtttt tattgatttc cattcttgct ggttgttcat
    29701 caccgccaga gccaacaccc gtgcagtttg aaaaggcaaa tgaagtgatc aatccctcat
    29761 tgccatatgt ccccgatttt cacggtgtca taaagtcaga cgttagcggt aaaggatggg
    29821 tttatgagat cacttcctta tccggagtac aggccagaac gccgacgttt tattacgctc
    29881 tggctcatgc ggacaggatt gtagtgacaa cacatgatgc tgggctgtgg tttcgaatca
    29941 gagatctgtt gaagatggaa ggggcaacag cagtcgtgga atggcgaaac gagaaaagtt
    30001 ttttacctga acaggtaaaa atagttttca ttaaagcaca aaatgaggtg aaaaatgact
    30061 ggaaaaaata gagtggtttt accagccttg ctggcgttag gattaatatc aacaaatgct
    30121 aatgcatctg acccttgcgc ttcggtactt tgcttatatg gaaaagcagt cgggcaaggt
    30181 ggagggagtg aatgcagaag tgctgaaaag gattttttta atattctgaa aaagaaaaaa
    30241 ggaagcattc gctggagtaa aacttttgat gcccgtaaag catttctgaa tcagtgttca
    30301 acggctgatc ctgctgctat atcaaaaatc atgagtaagt tcggcaaggt taaagggtag
    30361 atgatatgga aaagcaaact actgatttac tgaatgtaat caagacagga cactctggct
    30421 caatagctgg taatcctgct catgcactgg atgataagac tatgaacgcc atcattcata
    30481 actacgtggc aacgattgtg ctcggtaaag caggtaactg caaagaaact cctctcacaa
    30541 agtattgttc gaggactatg ccagagcgta tttcagttga agaaattaat gagtttaaaa
    30601 tttatccaga gttattctga acggagataa cggcaaacgc cgcagattcc ggattttaat
    30661 ccgggatttg cggggttgaa caaccgaagg gcgttagttt cctcgtaatc catgaggtgt
    30721 atatgaaagc aagaagtgtg agagttgccg gaattgaaat tatcgatagt gttaaaacgg
    30781 tcgcttttgt ttttactgaa accttactgt ttatggtctg gttttcggca attgtctatg
    30841 ggctttatcg tgttgttatc gttttatggg atgatccttt aaagccgcaa tcgctcatgg
    30901 aatttcttaa tttcatagtt gagttgtata gctatgtact tccttcgttg gctgttatcg
    30961 cagtggcttt aatcgccgtt ttatccattt gtaaaatact ctcagcaata tgggagggaa
    31021 gaaagcaatg agacattttc ttaaggctct ttcctttgtt gtttccctgt taccagctac
    31081 attgtgtgcg gctgaaatcc aggggaaagt tattcgcgtt ctcgatggcg acaccataga
    31141 aattaaaaca ctacccgcaa aaattgttgt gtatgaagtt ccgatccgag tccgattgat
    31201 aaacatcgat gcccctgaaa agaaacaacc ttttggacgc tggtcaacta gtcagcttaa
    31261 aactctggtt gcaggtaaac aggtgacagt ctcttattca cataaagacc gctacggacg
    31321 cattatcggt catgtgttca cgacgaacgg cacggatgcc agccgcttta tggttcagtc
    31381 tggcgctgca tgggtatatg aacgttacaa cgtggatgag tcattaccgg ctctgcaacg
    31441 ggaagcgcag gaacaaaaac gcggtttgtg ggccgatgca aatccggttc caccgtggga
    31501 atggcgatac aaacataact aactgataga ggtttttatg gctttatcac ccaaagaaaa
    31561 gaaagagtta caacaacgct tcgaaaagca attactacct gaccttgata tgtcatttga
    31621 actaaatggc gaagtatata aatttaattt tgataaaaat gagtcaggtg actatatcga
    31681 tagttttaca caagcagtat ggggaggtta tcaggatgcc gaggaatggg aaaaatatgg
    31741 taaacatcag gagacagaat tacctgaatg ccctgaacca gtcgagggtt ggtgcgactg
    31801 tgataaatgt aagtcgatga tttttcataa agagaaaaat atttatgttt gcctctcctg
    31861 ccataaacaa acagagccat ttcttccaat tgactggaac tcaaacgatt acgattggct
    31921 accttatgaa gatgaatact aatgctgaat acttcacagt cataatacag attgttcttt
    31981 attcaaaaga caaccatcta ttgaaagtgc attagttata taaatcagat actctttggt
    32041 ggttattatg caatatgcat tagttgatgc gctggaacga aaatttttgc tggatgctct
    32101 tgaatttggt gttctgaagg actggaaaga aaatccggta aaagaacttc ctgatattga
    32161 tgaatctgtt caccccttcc atgtctgcta tggtggatat ttattaaatc ctggtgtttc
    32221 agattcagat attagcagaa aaataaaaga ccagacagga ttctggctgg cagctattga
    32281 tgatacccgc atggattgtc attcaatagc ttattatgat attcacaccc tccctttgat
    32341 tttgtgtgga catcaaaaga tagttccttt tgccgcatta ataaaagctg atgaatgcat
    32401 catttcaaaa attgcttcat attctggttt tgctgtaaca gcttttttga gaattaaaga
    32461 ccaggatatc gcaacgaata tacttaaccg tgagggaatt tttgccttta atggctgtga
    32521 gcgcagattc agacaacctg taagtgaaga taactggcaa caggcagtat cagaagaacg
    32581 cgctattcgt tgtgcaaaca gattaattca atgtaaagga taacaaaatg agacttttta
    32641 tcgcagaaaa acccgcagta gcaaatgata ttgttaaggc acttggtggc aattttaccc
    32701 gccatgatgg ctggtttgaa agtgataacg ccattgtgac taactgtttt ggtcatatta
    32761 tcgaatcaca gccgccggaa aactataatc ctgaatacaa agcctggaag gttgaaacgc
    32821 ttcctttacg tctttatccc gtgaagtatc agcctgttga aagtgcagca aaacaggtta
    32881 aaacgattct cgagcttatc agacgtggag acgtgactga aattgttcac gctggcgatc
    32941 ctgatgatga gggacagcta cttgttgatg aagtcctgga atatgcagga aacacaaaac
    33001 ccgtaaagcg cgttctgatt aacgacaaca cgcttccggc agtgaaaaag gcactggcaa
    33061 atcttaaaga taatcgtgat ttcaaagggc tttaccttaa ggcgctggcg cgttcagttg
    33121 ctgatgccgt ctatggcttc tccatgacgc gtgcttacac cattcctgca aaagccagag
    33181 gatatcaggg cgttctgtct gtcgggcgcg tccagactcc cgttcttggc ctgattgtga
    33241 atcgtacccg tgctaaccag aaccataaat ccagttttta ctacaccatg accggagtct
    33301 ttcagcgtgg tgctgatgtt atcagggcga actggaagcc aggggaattt gctccgctga
    33361 cagaccgtaa attacttgat aaagcgtggg cagacggaac ggctgcatcc cttgcaggaa
    33421 aaccggctac agttgaagca gcagcaactg atgataaaaa aacggctgcg ccgttgccgt
    33481 ttaatctggt cagactccag caatacatga acaagaagtt taaaatgacg gcacaaaaaa
    33541 cgctggatat tacgcaacaa ctacgcgaaa aatataaagc aattacgtat aaccgctctg
    33601 actgctcata tctttcagat gaacaattca gcgaagcgcc gcaggttatc gatgccctga
    33661 aatcagtctt tcctcagtcg ctggatattg attctgcacg taaaagcaaa gcgtttaaca
    33721 gtgcaaaggt gactgcgcat actgcgataa tcccgaccgc cagtgtgcct gatgttaacg
    33781 cactcagcac cgacgagcgc aatgtttacc ttgcgatcgc acaacactat cttgttcagt
    33841 tcatgcctga a
//
