LOCUS       NZ_CP062367            27068 bp    DNA     circular CON 13-MAY-2024
DEFINITION  Staphylococcus aureus strain NAS_AN_123 plasmid pSAP046A, complete
            sequence.
ACCESSION   NZ_CP062367
VERSION     NZ_CP062367.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN15567930
            Assembly: GCF_022405355.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 27068)
  AUTHORS   Cella,E., Sutcliffe,C., Jubair,M., Weatherholtz,R.C., Reid,R.,
            Reid,A., Quay,D., Azarian,T.H. and Hammitt,L.
  TITLE     Carriage prevalence and genomic epidemiology of Staphylococcus
            aureus among Native Americans in the southwest US
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 27068)
  AUTHORS   Cella,E., Sutcliffe,C., Jubair,M., Weatherholtz,R.C., Reid,R.,
            Reid,A., Quay,D., Azarian,T.H. and Hammitt,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-JUL-2020) Burnett School of Biomedical Sciences,
            University of central Florida, 4111 Libra Dr, Orlando, FL 32816, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2020
            Assembly Method                   :: Uniclycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50x
            Sequencing Technology             :: Illumina MiSeq; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022405355.1-RS_2024_05_13
            Annotation Date                   :: 05/13/2024 04:02:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,999
            CDSs (total)                      :: 2,917
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 55 of 97
            Pseudo Genes (incomplete)         :: 46 of 97
            Pseudo Genes (internal stop)      :: 18 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP062367.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..27068
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="NAS_AN_123"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pSAP046A"
                     /collected_by="UCF"
     gene            complement(join(26456..27068,1..269))
                     /locus_tag="IF713_RS14820"
                     /old_locus_tag="IF713_14770"
                     /pseudo=""
     CDS             complement(join(26456..27068,1..269))
                     /locus_tag="IF713_RS14820"
                     /old_locus_tag="IF713_14770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581923.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0000155 - phosphorelay sensor kinase activity [Evidence
                     IEA]; GO:0004673 - protein histidine kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="sensor histidine kinase"
     gene            complement(266..>643)
                     /locus_tag="IF713_RS14825"
                     /old_locus_tag="IF713_14775"
                     /pseudo=""
     CDS             complement(266..>643)
                     /locus_tag="IF713_RS14825"
                     /old_locus_tag="IF713_14775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834602.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /name="response regulator transcription factor"
     gene            complement(701..1375)
                     /locus_tag="IF713_RS14830"
                     /old_locus_tag="IF713_14780"
     CDS             complement(701..1375)
                     /locus_tag="IF713_RS14830"
                     /old_locus_tag="IF713_14780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            1849..3315
                     /gene="msr(A)"
                     /locus_tag="IF713_RS14835"
                     /old_locus_tag="IF713_14785"
     ARG             1850..3312
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="99.8"
                     /coverage="100.0"
     gene            3414..4313
                     /locus_tag="IF713_RS14840"
                     /old_locus_tag="IF713_14790"
     CDS             3414..4313
                     /locus_tag="IF713_RS14840"
                     /old_locus_tag="IF713_14790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000196697.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            4799..5407
                     /locus_tag="IF713_RS14845"
                     /old_locus_tag="IF713_14795"
     CDS             4799..5407
                     /locus_tag="IF713_RS14845"
                     /old_locus_tag="IF713_14795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583528.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            5653..5991
                     /locus_tag="IF713_RS14850"
                     /old_locus_tag="IF713_14800"
     CDS             5653..5991
                     /locus_tag="IF713_RS14850"
                     /old_locus_tag="IF713_14800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001049146.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            5996..6181
                     /locus_tag="IF713_RS14855"
                     /old_locus_tag="IF713_14805"
     CDS             5996..6181
                     /locus_tag="IF713_RS14855"
                     /old_locus_tag="IF713_14805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000797248.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(6408..7151)
                     /locus_tag="IF713_RS14860"
                     /old_locus_tag="IF713_14810"
     CDS             complement(6408..7151)
                     /locus_tag="IF713_RS14860"
                     /old_locus_tag="IF713_14810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            7577..8560
                     /locus_tag="IF713_RS14865"
                     /old_locus_tag="IF713_14815"
     CDS             7577..8560
                     /locus_tag="IF713_RS14865"
                     /old_locus_tag="IF713_14815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001181107.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            <8580..8869
                     /locus_tag="IF713_RS14870"
                     /old_locus_tag="IF713_14820"
                     /pseudo=""
     CDS             <8580..8869
                     /locus_tag="IF713_RS14870"
                     /old_locus_tag="IF713_14820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            9416..9565
                     /locus_tag="IF713_RS14875"
                     /old_locus_tag="IF713_14825"
     CDS             9416..9565
                     /locus_tag="IF713_RS14875"
                     /old_locus_tag="IF713_14825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000695366.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(9733..10425)
                     /locus_tag="IF713_RS14880"
                     /old_locus_tag="IF713_14830"
     CDS             complement(9733..10425)
                     /locus_tag="IF713_RS14880"
                     /old_locus_tag="IF713_14830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            10535..10729
                     /locus_tag="IF713_RS14885"
                     /old_locus_tag="IF713_14835"
     CDS             10535..10729
                     /locus_tag="IF713_RS14885"
                     /old_locus_tag="IF713_14835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            11845..12462
                     /gene="cadD"
                     /locus_tag="IF713_RS14890"
                     /old_locus_tag="IF713_14840"
     ARG             11846..12459
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            12481..12828
                     /locus_tag="IF713_RS14895"
                     /old_locus_tag="IF713_14845"
     CDS             12481..12828
                     /locus_tag="IF713_RS14895"
                     /old_locus_tag="IF713_14845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            12985..13077
                     /locus_tag="IF713_RS14900"
                     /old_locus_tag="IF713_14850"
     CDS             12985..13077
                     /locus_tag="IF713_RS14900"
                     /old_locus_tag="IF713_14850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(13249..14220)
                     /locus_tag="IF713_RS14905"
                     /old_locus_tag="IF713_14855"
     CDS             complement(13249..14220)
                     /locus_tag="IF713_RS14905"
                     /old_locus_tag="IF713_14855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_000481279.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            14344..14763
                     /locus_tag="IF713_RS14910"
                     /old_locus_tag="IF713_14860"
     CDS             14344..14763
                     /locus_tag="IF713_RS14910"
                     /old_locus_tag="IF713_14860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            complement(15289..16134)
                     /gene="blaZ"
                     /locus_tag="IF713_RS14915"
                     /old_locus_tag="IF713_14865"
     ARG             complement(15293..16134)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            16241..17998
                     /gene="blaR1"
                     /locus_tag="IF713_RS14920"
                     /old_locus_tag="IF713_14870"
     ARG             16242..17995
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            17988..18368
                     /gene="blaI"
                     /locus_tag="IF713_RS14925"
                     /old_locus_tag="IF713_14875"
     ARG             17989..18365
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            18632..19210
                     /locus_tag="IF713_RS14930"
                     /old_locus_tag="IF713_14880"
     CDS             18632..19210
                     /locus_tag="IF713_RS14930"
                     /old_locus_tag="IF713_14880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690637.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(19433..19618)
                     /locus_tag="IF713_RS14935"
                     /old_locus_tag="IF713_14885"
     CDS             complement(19433..19618)
                     /locus_tag="IF713_RS14935"
                     /old_locus_tag="IF713_14885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001037130.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            19880..20554
                     /locus_tag="IF713_RS14940"
                     /old_locus_tag="IF713_14890"
     CDS             19880..20554
                     /locus_tag="IF713_RS14940"
                     /old_locus_tag="IF713_14890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105991.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(20723..21294)
                     /locus_tag="IF713_RS14945"
                     /old_locus_tag="IF713_14895"
                     /pseudo=""
     CDS             complement(20723..21294)
                     /locus_tag="IF713_RS14945"
                     /old_locus_tag="IF713_14895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /name="HTH domain-containing protein"
     gene            complement(21570..22364)
                     /gene="aph(3')-IIIa"
                     /locus_tag="IF713_RS14950"
                     /old_locus_tag="IF713_14900"
     ARG             complement(21574..22364)
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(22457..22987)
                     /gene="sat4"
                     /locus_tag="IF713_RS14955"
                     /old_locus_tag="IF713_14905"
     ARG             complement(22461..22987)
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="97.78"
                     /coverage="100.0"
     gene            complement(22984..>23619)
                     /locus_tag="IF713_RS14960"
                     /old_locus_tag="IF713_14910"
                     /pseudo=""
     CDS             complement(22984..>23619)
                     /locus_tag="IF713_RS14960"
                     /old_locus_tag="IF713_14910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251744.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="aminoglycoside 6-adenylyltransferase"
     gene            complement(23760..24434)
                     /locus_tag="IF713_RS14965"
                     /old_locus_tag="IF713_14915"
     CDS             complement(23760..24434)
                     /locus_tag="IF713_RS14965"
                     /old_locus_tag="IF713_14915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105956.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(<24491..24667)
                     /locus_tag="IF713_RS14970"
                     /old_locus_tag="IF713_14920"
                     /pseudo=""
     CDS             complement(<24491..24667)
                     /locus_tag="IF713_RS14970"
                     /old_locus_tag="IF713_14920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499250.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016311 - dephosphorylation [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /name="undecaprenyl-diphosphate phosphatase"
     gene            complement(24681..25418)
                     /locus_tag="IF713_RS14975"
                     /old_locus_tag="IF713_14925"
     CDS             complement(24681..25418)
                     /locus_tag="IF713_RS14975"
                     /old_locus_tag="IF713_14925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="WP_000369394.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            complement(25411..26340)
                     /locus_tag="IF713_RS14980"
                     /old_locus_tag="IF713_14930"
     CDS             complement(25411..26340)
                     /locus_tag="IF713_RS14980"
                     /old_locus_tag="IF713_14930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000793446.1"
                     /translation="MKNLNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAG
                     KTTTIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTIN
                     AKILGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPT
                     NGLDPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYED
                     LKKKNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLN
                     NIDVFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     ARG             3415..4310
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             1850..3315
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.16"
                     /coverage="100.0"
     ARG             3415..4313
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             complement(22458..22975)
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="97.16"
                     /coverage="95.56"
     ARG             complement(15290..16134)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     ARG             complement(23282..23583)
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     Typing          8926..9073
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(6409..7151)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          7578..8560
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          8692..8861
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.605"
                     /coverage="91.0"
                     /evalue="1.04e-65"
ORIGIN
        1 gactctaact cactttggta gttaataaag tcattacgaa gtttatggtt ttcgattctt
       61 aaatcttcgt tctgttcctg tagtgtttat tcttttttaa agttcatgta atggataccc
      121 cagtaaatca ttgaaacaaa caatacaata cctagaccaa tcatatatgc ttgcatcggc
      181 acattataca tgaataatat aaagtagaat aaagcacaag taaggatgac aatataaatt
      241 tcacgttgga ttgatttcaa gaaattcata cgtcacctac acgatatccg acatttttct
      301 tcgtttcgat aaaatctgta agtcctagtt tttgtagctt tttgcgtaaa cgtgtaatgt
      361 tgacagcaag cgtattgtca tcaatgaagt gttctgattc ccagcatttt tcgattaacg
      421 cattacgact gacgaatttg cccttgttct ggaataagct atgcatgatt tgcaattcag
      481 tgtgtgtcag gtctatggtt tcttcattaa atttaagctt tgctgcatca agtagtaact
      541 cgcaatcatc tactgttaaa ttattaactt gagtggtgaa atcatacgtg cggcgtaata
      601 gtgcttgaat cttagtaatt gtaacagtca tattaaatgg ctggttctgt tgcaaagtaa
      661 aaaatatagc taatcactaa tatatcatgt cagtgttcgt ttaacttgct agcatgatgc
      721 taatttcgtg gcatggggaa aatccgtaga tctgaagaga cctacggttc tttttatata
      781 gagcgtaaat acattcaata ccttttaaag tattctttgc cgtattgata ctttgatatc
      841 ttgtctttct tactttaata tgacggtgat cttgctcaat gaggttattc agatatttcg
      901 atgtacaatg acagtcaggt ttaagtttaa aagctttaat tattttagcc attgctgcct
      961 tcgttgaagg tgcctgatct gtaactacct tttgaggctt accaaattgt ttaatgagac
     1021 gtttgataaa cgcatatgct gaatgattat ctcgttgctt acgcaaccaa atatctaatg
     1081 tatgtccctc tgtatcaatg gcacgatata aatagctcca ttttcctttt attttgatat
     1141 acgtctcatc aatacgccat ttgtaataag cttttttatg ctttttcttc caaatttgat
     1201 ataaaattgg ggcatattct tgaacccaac ggtagatcgt tgaatgatga acgtttacac
     1261 cacgttctct taatatttca gatatatcac gatagctcaa tgcatatctt agatagtagc
     1321 caacggctac agtgataaca tccttgttaa attgtttata tctgaaatag ttcatacaga
     1381 agactccttt ttgttaaaat tatattataa attcaacttt gcaacagaac cgtattttat
     1441 gagtacactc taaattaagg agatgtataa tcaatctaaa attgtatttt tatacttttg
     1501 ttatataatc tttctactta gagatatatt gtaaaaaaac caacaaaatg ttatattaac
     1561 attactattt tatcgatgaa ggaggattaa aatgacagct tctatgagac tcaaataaac
     1621 ctttttgaat acaaaactaa attaattcaa aaaggcttgt ccgcaataca cactcatagg
     1681 atgacttatg tcatttttta tccttcgata ggaataataa acgctttcaa atactaaaac
     1741 atcataataa atttttaagt gtttgaaagt gtaatgtgaa tgagacggga gtagcctgtc
     1801 tcattttttt gcgtacacgt cctttaaata tacaaggagt gtataaatat ggaacaatat
     1861 acaattaaat ttaaccaaat caatcataaa ttgacagatt tacgatcact taacatcggt
     1921 catctttacg cttaccaatt tgaaaaaata gcacttattg ggggtaatgg tactggcaaa
     1981 accacattac taaatatgat tgctcaaaaa acaaaaccag aatctggaac agttgaaacg
     2041 gttggcgaaa ttcaatattt tgaacagctt aacatggatg tggaaaatga ttttaacacg
     2101 ttagacggta gtttaatgag tgaactccat atacctatgc atacaaccga cagtatgagt
     2161 ggtggtgaaa aagcaaaata taaattagct aatgtcatat caaattatag tccgatatta
     2221 cttttagatg aacctacaaa tcacttggat aaaattggta aagattatct gaaaaatatt
     2281 ttaaaatatt actatggtac tttaattata gtaagtcatg atagagcact tatagaccaa
     2341 attgctgaca caatttggga tatacaagaa gatggcacaa taagagtgtt taaaggtaat
     2401 tacacacagt atcaaaatca atatgaacaa gaacagttag aacaacaacg tcaatatgaa
     2461 cagtatataa gtgaaaaaca aagattgtcc caagccagta aagctaaacg aaatcaagcg
     2521 caacaaatgg cacaagcatc atcaaaacaa aaaaacaaaa gtatagcacc agatcgttta
     2581 agtgcatcaa aacaaaaagg cgcggttgag aaggctgctc aaaaacaagc taagcatatt
     2641 gaaaaaagaa tggaacattt ggaagaagtt gaaaaaccac aaagttatca tgaattcaat
     2701 ttcccacaaa ataaaattta tgatatccat aataattatc caatcattgc acaaaatcta
     2761 acattggtta aaggaagtca aaaactgcta acacaagtac gattccaaat accatatggc
     2821 aaaaatatag cgctcgtagg tgcaaatggt gtaggtaaga caactttact tgaagctatt
     2881 taccaccaaa tagagggaat tgattgttct cctaaagtgc aaatggcata ctatcgtcaa
     2941 cttgcttatg aagacatgcg tgacgtttca ttattgcaat atttaatgga tgaaacggat
     3001 tcatcagaat cattcagtag agctatttta aataacttgg gtttaaatga agcacttgat
     3061 cgttcttgta atgttttgag tggtggggaa agaacgaaat tatcgttagc agtattattt
     3121 tcaacgaaag cgaatatgtt aattttggat gaaccaacta attttttaga tattaaaaca
     3181 ttagaagcat tagaaatgtt tatgaataaa tatcctggaa tcattttgtt tacatcacat
     3241 gatacaaggt ttgttaaaca tgtatcagat aaaaaatggg aattaacagg acaatctctt
     3301 catgatataa cttaaaaact atacactaat ttatattgaa tattaggttc atttatatca
     3361 atataaaaaa tacgttcaca agaaaaatat aatagaaata aggatccaat aaaatgactc
     3421 gacataatga aattattaaa tgtgcagaaa aatatcaatt acacatccaa cctcaaacaa
     3481 tctcattgaa tgaatcggga cttgattttc aagttgcatt tggaaaagat aaacatggag
     3541 tagaatgggt tttgagacta ccaagaagac ctgacgttta taaacgaaca aaacccgaaa
     3601 aacaaacggt agacttctta cagaagaatg tttcatttga aataccgaag tggaaagtac
     3661 atgcaaaaga ccttattgct tacccaaaac ttacaggtaa acccgcagcc acaatagatc
     3721 cagaaataca aaattatgta tgggaaattg aacacaaacc attaccagaa aactttatta
     3781 acacattagc tgaaacactc gtagatttac acaacatacc agaagaaaac attaacgttc
     3841 agcatataaa tatcaaaacc atacaagaaa taaaaaatga ctttcaaaga agaatgaata
     3901 aagttaaaga aacttatggc gtatcagatg aattatggaa cagatggaaa caatggttag
     3961 aaaacgacga actatggcct cgacatgcga ccatgataca tggggactta catccaggac
     4021 atataatggt agataaccaa gcaaacgtca caggtctcat agactggact gaagcaaccc
     4081 actccgaccc atcaatggac tttataggac accatcgtgt attcgacgac gaaggattag
     4141 agcaacttat aacagcatac ggtaaagctg gaggtgaaat atggccacga atgaaagagc
     4201 atataataga actcaatgca gtattcccaa tgtttatcgc tgagtttgct atggaatcag
     4261 gagaatcggc gtatgaaacg atggcattga aagagttagg tatgaaagag tagaacttat
     4321 attaaaagag gcccatttta aagacgaagg caatcctgat gaaattttaa aactgcgttt
     4381 aattagtgat ggtctttggt tttctataat gtattaaata tctggacatg gaacaaatgc
     4441 aacaaatgga aagaatcgtt ttcgaaattt ctaactcctt aaatcaggag gataaataaa
     4501 cggtcatttt cattgaaagc acttatataa atttcatcaa ttttaatacc taccgtaaat
     4561 acatttcata agtattaaac agatgattaa aatttttagt taatttaaat atttatgata
     4621 gagatgacct tcaaatgaac ggttctgtta caaagaaaaa atctatattt atttttagta
     4681 agttttaatt atagatatgt acactttgag tacaccctaa ccatacaaaa agaattgttg
     4741 aaattataac aattaaaacg tatgattagg gtgtatattt attatggagt gaagatgaat
     4801 gattataggt tatgcgagag tatcatcgat agatcaaaat ttagaaagac aattggataa
     4861 tttaaagacg tttggtgtgg agaaaatctt tacagagaaa cagtcgggaa agtcagtgga
     4921 aaatagacct gtatttcaag aagcactcaa ttttgtcaga atgggagatc gattcgttgt
     4981 ggaatctatt gatcgtttag gacgtaacta tgatgaaatt attgaaactg tgaattattt
     5041 aaaagaaaaa gacgttcagt taatgattac cagcttacct atgatgaatg aagtaattgg
     5101 caatccatta ctggataagt ttatgaaaga tttaatcatt caaatattag caatggtttc
     5161 agaacaagag agaaatgaaa gtaaacgtcg acaagcgcaa gggattcaag ttgcgaagga
     5221 aaaaggcgta tataaagggc gccctttact ttattcacca aatgctaaag acccacagaa
     5281 acgtgttatt tatcatcgcg tggtggaaat gttagaagaa ggcaaagcga ttagtaagat
     5341 tgcgaaagaa gttaatatca caagacaaac agtttataga attaaacatg ataagggatt
     5401 atcttgataa attgattgtc aatgcaaatg agcgtctctc acagtgtctc aaattccata
     5461 acatattatt gaattgagat tttaataatt atacaagaaa aaagagtacg agttcgcagc
     5521 tttctatata gtaattgttt tactaataag gtgttttaaa atatattata atgtaaaaag
     5581 tatttgacat ttgtatcaaa aatatttaca ctcataaatg tcaaatactt tttacattta
     5641 tgaggtgtta taatgaattt aattcctttt attattattt taattttttc ttgtttatgg
     5701 acggctataa ctaacaaata tttaccttca gaaacattag ataaaaaagg acaacaagat
     5761 cgatacgatg aaagacaacg taaaatgttt attgaaatac tggctaaaag ttttatttgg
     5821 attgtatatt gtatgttatt tacactagtg cttaaattta caggtttgtc accaagtatt
     5881 gaaggatctt ggttttctca atatccagaa attttcttta taattgtagc actatttctt
     5941 atgctgttta attactatac tacaaataaa aaatatacat ctaaaggtta aattaatgaa
     6001 aaatagaatt agagaatata gaaaacaaaa aggaatttct caagaaactt taagtaaaga
     6061 attaaaagtg tctaggcaaa ctattaatgc aatagaaaac aataaatatg atcctacatt
     6121 gacattagca tttaagttgg caagattgtt tgatacaact gtggatgaat tattttctta
     6181 accattcatt tatcacaaaa agagagtgcg aattcgcact ctctttttgt gtagtagtac
     6241 tattaaattt tgtctcaata acgaacgttt ataacgcaat catgatgaga gtattaatac
     6301 agttaattat ttgaaatact ttagtttaca taatcgatga ttaccagaag ttctcactat
     6361 ataaaagaca ctaaaatttt ataactttta gtgcctaatc aattatttta gctaccaaac
     6421 aaacgactcc aaaacccctt tttaggttcc gtttcttcac tcttttcttc tatatcacta
     6481 tcattgtcat ttagattagc tggaacgtct tctttttttg cttcttcacc ttgtgtactt
     6541 tcgtcgcttt gacttccaga tatatcctta tattgaatct ctgtttcttt agtttcttcc
     6601 tgatctctgt taatatttac aggattagta gtatatgttt tttcttgtgc atcaacgttt
     6661 tgtctagtgt tagtagatgt atcaaaggga taattaaggt gtttttcttt ttctaattga
     6721 ttttctaatt tttgaatctt tttattactc tctaatgcca gaacttgctg attttcaagc
     6781 aattttgatc tttcttgcaa ctcttttctg taaaattcaa ttgttgtttc atgacgactt
     6841 tcttgttttt caatttgatt atttaaagta tcaatctgat ttttaaggat ttctactatt
     6901 tgagcatcgc ttttcgattc aaaattaata ttatccgacc cttttttttg tttgtcttca
     6961 gtagtacttt caaaaccata tttcttttta ttttcattta ctctttgaat gattttttct
     7021 atatcggtat cttctttaat aaacgaagtg ttttcctgtt ttattgtctc tatattcaat
     7081 cgcttaatat tattaaaaat cgtttgctta ctaaccccta attcttcact caactttttc
     7141 acacttttca tatcatcaac cctttataaa atgtttataa acccttgata aaatattata
     7201 agcttataat gcttaataat aaagtgatta ataaataaaa ataaacatcc atcaaccttt
     7261 ttatcaaggg tttatgaaag gtttatgata tttatcaagg gtttataaac ccttgataaa
     7321 gctatatttt cccttttata agtttattta aagtgctata ataaacttaa tataacaaaa
     7381 accccaacta ctggtaatag tcggggtttg gtaataaaac gtttagaaac tgtttattta
     7441 tataattttc gatacttgta ttatataatg aataatatct tagtgcaagc acctaaatca
     7501 ttaaataaat gtaaagctaa ataaaaacgt tttattacct cttaccaaac taaaatatgg
     7561 aaagaggttt tttgtcatgc aaaatcaata ttttacagtg caagaaaatt acaaagaaag
     7621 attttatcaa atccctaaag tattctttac cagtgaaaat tataaaaatc taactaatga
     7681 tatgaaaata gcctatgcta tcttacgtga tcgcttaaat ttatctatta aaaatagctg
     7741 ggttgatgaa gatggtaaca tttactttgt ttattcaaat gaaaagctaa tggaaatctt
     7801 aaattgtaaa aaagaaaagt taacaaaaat aaaaaaaggg ttagaaaacg atggtctact
     7861 cattcaaaaa cgacgtggtt taaataaacc aaatattcta tatttaatga aacctattgt
     7921 cacagaacgt gatatttaca aaatagaaaa agaagaaaac gatgttgaac cttacggcga
     7981 gaaggaagtt cgaaaatcga acgtccagaa gttcgaaaat cgaacgtcca gaagttcgaa
     8041 aatcgaacgt ccagaagttc gaaaatcgaa cactaatgat actgacttta atgacattga
     8101 ctttaatgat actgagaata atgatatgaa tgacttgaat gatataaagt acaaaaatga
     8161 aattagtaat cattcaaatc attcaaatca atttacacat aattttgatg ataaagaaat
     8221 gctattgcaa gaattcccag aacaactaac taattattta ttaaaatatg attatagaga
     8281 tttagaaatc ataaaggctg ttattcttaa agcaaaaaaa tcatttaatt caaggcatga
     8341 agatatgcat tacatgttag aggacattga ggatgaaata ttaacttctt taaaaagact
     8401 taaaaaagct atacatgata ggggagttaa aggccaaaag gaaacaatca agtcaatgca
     8461 agcttattta atgcaaacaa ttctaactga acttgaagaa acacatgccc tttatatgcg
     8521 ccgtaaaaac atgaaacaat ataatatctt taatcaataa ttcaaatgat tttataacac
     8581 tcgaagagac atcaaaatat tccgttaaat catctgactt tttaactgat gacgacgaaa
     8641 aaaatcaaga aattgtaagt gatttagaaa aaggtttgta tcgaaaacgt atgttaagtt
     8701 atggtggatt gcttaaacaa aagcataaaa ttttaaactt agacgatgcc gaagatggta
     8761 atttgattaa tacaagtgat gaagataaaa cgacagacga agaaaaaaag cacattcaat
     8821 taccgcaatt tggaatttcg aaaagcaaaa ttattattta agacattagt gataactgat
     8881 gtcttttttt attgtttttc tgtaaaaaag tgctgtctta tttttgtgac aaatgctgta
     8941 tgtagtgtca caaaagtgtg acactacagc tttgtatgat atcactttaa aataacttaa
     9001 aacccttgga atgtctggcc ttgccagatc tatcattttt gaatgatagc aaatttccct
     9061 tatgctctta cggagatttt agagttaaat taaaatttct aagtttttga taagaaaagc
     9121 cctgcaggaa tttagaaaaa catggggaag ttttaaagta ttttatgcta atttttaaat
     9181 ttgcatgtaa atgggcagta tctaaaaaat tagtcactga ttttgctgaa atttttgttt
     9241 gtgaaattag catatattta tttggctcat atttgcgttt taagagactg tatagatttt
     9301 taagtacaaa acctatatga tttgcctcta agtcttcaaa atgcctctta aaatccaaaa
     9361 taaaagtgtt taatattgta ataaggattg ctatttttat aaaaggagag atatcatgaa
     9421 gattaaaact ttcgctactt ttactcatcg tcaattagat aaacaagtta ataggttttt
     9481 aaagaatgat attcatgtat tagaaattca aacacacagt aattggttat atatttcagc
     9541 tattgttttt tatgaggata aataaggaac atcgtattta tgccgaaaaa atttattgat
     9601 gttgagaaga acccttaact aaacttgcag acgaatgtcg gcatagcgtg agctattaag
     9661 ccgaccattc gacaagtttt gggattgtta agggttccga ggctcaacgt caataaaaca
     9721 attggaataa aatcaaccta cagagcatcc agctgcaaat gcagttccgc aaactgcttc
     9781 acatacaccg ccggctattg gatttacgat tgcccatact ccacagtagt gagcacatgc
     9841 ataaagtcca gccatactac aagcgaatgc tttgccgttc catttgaatc ctgcatatgt
     9901 taccggtctg tttttatcaa ctttttcagc cttatattca acgtaatttt tgttaataag
     9961 tatttttccc tctttgtttt cagtcatact tcttttttcg gcaatgaatt ttgtgatttt
    10021 tttgttgtag ttatcatata ttgtttcaga aactacaatt tcttttgttt tttcattttt
    10081 ataagcgtta ttagctatgt agccatatgc atttttatca tttgcttctg tagctagata
    10141 ttttaattta gaatttttgt cttctagctt tattttttta aatccttctt ttttcatttg
    10201 cttttcgaat ttttgcatat cttcattttt attttgcaat tgttctagaa aacttatttc
    10261 tttcttggtc atttgtgata cttcgatgtt tttgcttttc aatttttctt tttgattttc
    10321 tagtaaagaa cttttttgtt cttcatttgc gtaagcatta gaaaaattcg cgctaaatac
    10381 cagtaggaac aaggaaatta ttgaaaataa ttttataatt ttcatttgat acctccaaga
    10441 taataagata ttttaattgt ataagtaagc gctttataaa atcaatattt attttaatat
    10501 atttataaac atatttttga aaggagtcta ttttatgaat gaaaatttag aaaaatatat
    10561 aaaaagtttg ccacttttag gtttgttaat tagtattttg ttaattgttt tattcttttt
    10621 tattttagat gttgatgaag atttattcgt ggttttttta tactgtttat tgcctttgat
    10681 agttaatttg tctatttatg gtttttatgt ttttgttaaa agaaagtaag attatgaata
    10741 attttgtttt taatttgtat gctttgaggg ggttggaaaa cggtaggtgt atagattaga
    10801 tttcttgttt ttttgaaacg agtgtgaacg agtttcttct tgtcttgatt tttgataaaa
    10861 acgccctaca ggaatttaga aaaacgtggg gaagttttaa agaattttat gctaattttt
    10921 aatttgcatg taaatgggca gtgtctaaaa atagttattg tttttgctca aatttttgtt
    10981 tttgaaaata gcatatattt atttggctca tatttgcgtt ttaaaagcat atataagttt
    11041 tagatataaa actatatgaa tcacccctaa atctttaaaa tgccctctta aaattcaaaa
    11101 taagggcata aaaaataaaa gctaccccag ataaagtgag gtagcttttt ctttcatacg
    11161 gtctatttat ttttctttcg acgccgtatc gtcgatgtaa ttcaaaaaag ttatgggcta
    11221 taaatctaca tcactttttc aagaatgtag tagcaatatt caacgcaaat taatttttat
    11281 aactgctcgg aatatctcaa gccgtttctt taattttgaa ataaaaaaat cgacgaaggt
    11341 cgattacgtt tttgcacatg tcgatttatc cgacgtataa gtgcgccctt acgggattta
    11401 actagattat aacgacgaat tttagacctg taaagcaata acaattaggt ctaccaggta
    11461 gataaagtgt acaaagtaga accgaaaaag ttatttattt tgaagatttt tcgtagatat
    11521 aatttgctaa taaacttcct aaaactgaat aaagaaaaat agttaaactc atgtaatcac
    11581 tccataattc tgaagtgtct ccatgtctac gcatagacac gcatttatgc cgaaaaaatt
    11641 tattgatgtt gagaagaacc cttaactaaa cttgcagacg aatgtcggca tagcgtgagc
    11701 tattaagccg accattcgac aagttttggg attgttaagg gttccgaggc tcaacgtcaa
    11761 taaagcaatt ggaataaagc acctatgatt atttaaaaat ataagttata atacattcaa
    11821 aaatattttt gaatgaggtg tattatgatt caaacggttg ttgctgctgc tgttctttat
    11881 attgctacag cagttgattt attagtaatt ttattaatat tttttgctag agcaaagact
    11941 agaaaagaat atagagatat ttatgttggt caatatttag ggtctattat tttaatatta
    12001 gttagtttgt ttttagcttt tgtattaaat tatgttccag aaaagtggat attaggttta
    12061 ttgggtttaa taccaattta tcttggaatt aaagtggcta tttatgatga ttgtgaagga
    12121 gaaaagagag ctaaaaaaga attgaatgaa aaaggattgt ctaaattagt tggtacggtt
    12181 gcaattgtta cgatagcaag ttgtggcgcc gataatattg gtttatttgt tccgtatttt
    12241 gtgacattaa gtgttactaa tttattactt actctgtttg tctttttaat tttaattttc
    12301 ttcttggtgt ttactgcaca aaaattagct aatattccag gaattggaga aattgttgag
    12361 aaatttagtc gttggattat ggctattatt tatatagctt taggtttatt tattattatt
    12421 gaaaatgaca ctattcaaac aattttagga tttatatttt aatttagggt gtgattttat
    12481 atgagttatg aaaatacttg tgatgtgatc tgtgtacatg aggataaagt taacaatgct
    12541 ttaagttttt tagaagatga taaatctaag aaattactta acattttaga aaaaatttgt
    12601 gatgagaaga aattgaaaat catattatct ttgattaaag aagatgagtt gtgtgtttgt
    12661 gatatttctt tgatattgaa aatgagtgtt gcttcaactt cacatcattt aaggctttta
    12721 tataaaaatg aggtacttga tttttataaa gatggaaaga tggcatatta ttttattaaa
    12781 gacgatgaaa taagagagtt tttctctaaa aatcatgagg gtttttgaaa cgagtttctt
    12841 cttgtcttga tactataaaa aacaaagtta tataacataa gacgacttat cggaagtaga
    12901 tatgcttgta tattcacaga tggtataata atagagtcgc ctatctctca ggcgtcaatt
    12961 gacgaagaga ggaggtgcat tactttgcta atcattttcg ttcacatcat agcaccagtc
    13021 atcagtggct gtgctgttgc gtattatact tattggctta gtaaacgcaa caaataatta
    13081 ataggcgact ttataagcca gcatcgaaaa aatccccaca ctactgcaat agtgtgggga
    13141 ttggtgcatt aattgttaat cattttcgtt atataaatta taacactggt tagtagagaa
    13201 atgcaaaatg attgaattaa tagtaaatgt attaatgaat actcacactt atacttttaa
    13261 aatagttctt cctaaatgtt gtccttttaa aagctgatct atcgttttat agaattcttc
    13321 aaatccaatt tcattgtata gaagtgaatt tcctatattc cattcatttg ctaacttact
    13381 ccatatatct tcacggatat tatgatcaac atatacagaa tcaatgccaa ttaatttaat
    13441 acctctaaga ataaacggta atatattagc gttaagtgaa tttcctgcta catttccaca
    13501 tacagtagca acaccttgat aatttagacg ttttaaaccg tataatgtta cattactccc
    13561 cactgtatct aagaaataat caaaaatacc ttttttaagc ggtttattat catcttcaat
    13621 tattattact tgttttgcac ctaatttttt tgcgatttct atttgctttt cttttcttac
    13681 gatagcagtg atattttcat atccaatttt atgtaaaatt tgtatagcaa cactgcccac
    13741 accacctgta gccccagaca ctaaaatttc aggttgtgat ttgatattca ttccatattt
    13801 ttctagttca aaaattgata atgctgccgt aaaaccggct gtgccatata ccatagactc
    13861 tttaatagac atttcttggg gaataggaac aatccactct ccaggcactt gtgcatattc
    13921 tgaaaatcca cctgtatgtg tcacgccaac atcataacca gtaactaata cattatcgcc
    13981 ttctttaaac ttatcattcg aacttgattc aacaatacct gcaaaatcta taccaggaat
    14041 cataggataa tctctaatta caccgccttt atattgtaaa gctagcatat ccttataatt
    14101 tattgaagag tataccactt ttactaatac atcacccttc gataaatgag attcatcaac
    14161 tttttctact ttataactaa catttgatgc actttttctc actactaccg cattgaacat
    14221 ttattagcct tctttcacaa ttgttttgta gaagtatgtt tttgttgcaa aactattttc
    14281 ctacaaaact tatcatgata tgataagcga gtcaatacta atgatttaag agaggtttta
    14341 gttgtggaat tagataattg tataaattat ttgttgagta cttctcagaa tagagttttt
    14401 aaacatttta aaagtttatt aagtccctat aatattactc cagcagaata tggtgttttg
    14461 aattgcttga ttaatagtaa tttgaataca cctaaagcga ttggtaatac tttaaattta
    14521 gaaccttcaa caatatctgg aatattagat aagatgtcca aaaaggatct aataacacgt
    14581 caaactgata atgaaaatag aagaactgtg ctaataaaca gtacaaataa agcaaaagac
    14641 ttatggccaa cattagaaaa gaaagcctat caacttaata atcattactt cgctaattta
    14701 actaatgaag aaactgtagt gtttaaaaag atattactaa agataaataa aactacgttt
    14761 taatttttac gttataaaaa agttgaagtg cgaattataa tcgagtaaat ataaatgata
    14821 gcttagctta attatatatt aaagccaact atacttttat tcccgaaaaa cctactatcc
    14881 aaatttctaa gatactttag cctctataat aaacatattg taatataatt tatgtattat
    14941 ttaggtttac cctaatcgaa caataaaaaa tacttgtaaa atgctattgt cactttgctt
    15001 gatatatgag aattatttaa ccttataaat gagaaaaaag caacgcactt taaataagat
    15061 acgttgcttt ttcgattgat gaacacctat aattaaacta ttcatctatt atttatgatt
    15121 ttttgtatat acaatatttc tagtttgtta aagagaatta agaaaataaa tctcgaaaat
    15181 aataaaggga aaatcagttt ttgatatcaa aattatacat gtcaacgata atacaaaata
    15241 taatacaaac tataagatgt tatcagtatt tattatgcat ttagaatatt aaaattcctt
    15301 cattacactc ttggcggttt cacttatcaa cttatcattt ggcttatcac ttttattgtc
    15361 tttattcgta aaaatgacta aaacaatagg ttcagattgg cccttaggat aaacaaaagc
    15421 aacatcattt ctagaagcat atgttattgc ttgaccactt ttatcagcaa ccttatagtc
    15481 ttttggaaca ccatctttaa ttaaagtgtc tccgttttta ttattaaaca ttaaatcaag
    15541 taagaaattt ttattttttt tgcttaattt tccatttgcg ataagtttat ttaaagtctt
    15601 gccgaaagca gcaggcgttg aagtatcttt tttgctcttt ggtgaatagt aatttaattc
    15661 tatctcatat ctaactggat ttgttacttt atctcctagt tcttttagac gttgtttaac
    15721 ttttttgatt ccaccgattt cttttataat tttattgttt gctgtattat cactatatgt
    15781 cattgaagcc tcaataagtt cttttaaagt gatatctttt cctacatatt tttctaaaat
    15841 aggagaataa gcaactatat catctttgtt aatatgtact tttttattta acttattata
    15901 aggtacttgt tctaacaaaa tagcactatt tatcgctttt gaagtcgaag cataggcaaa
    15961 tctcttatct gaattaaatt ttacttcctt accactttta gtatttaaag cataaacacc
    16021 aatatgagca ttatattttt tttctaaatc atttaactct ttggcatgtg aactgtttga
    16081 attacatgca cttaaaacta aagcaattac aattaaaaat attaactttt tcaaaataaa
    16141 ccctccgata ttacagttgt aatttttata aatcaataat attacaattg taatattgat
    16201 gtcaattgtt tattataaat atttgaaaga aggtgtcaaa atggctaaat tactaataat
    16261 gagcgtagta agcttttgtt ttatatttct attgttagta ttttttaggt acatattaaa
    16321 acgctatttt aattatagtt taaattataa agtttggtat ctaactatgc ttgctggatt
    16381 aattcctttt atcccaatta aattctcttt tataaaattt aataatgtga ataatcaagc
    16441 gcccacagtt gaaagtaagt cacacgattt gaaccataac ataaatacca ccaaacctat
    16501 tcaagagttc acaacagata tccataagtt taattgggat tcaattgata atatctgcac
    16561 agttatttgg atagttttag ttattatttt aagttttaaa tttttgaaag ccttattata
    16621 tcttaaatat ttaaagaaac agtcacttta tctaaacgaa aatgaaaaaa ataaaataga
    16681 tacgatactt ttcaaccatc aatataaaaa aaatattgtg attcgaaaag cagaggctat
    16741 tcaatctcca ataacttttt ggtatgggaa atatattatt ttgattccta gttcatattt
    16801 taaaagtgta attgataaaa gactaaaata tataatactg catgaatatg ctcatgctaa
    16861 aaatagagat actttacatt taattatctt taatatcttc tctattatta tgagttacaa
    16921 tccattagta catattgtaa aaagaaagat aattcatgac aatgaagtag aagccgatag
    16981 atttgtcctt aataatatta acaaaaatga atttaaaact tatgcggaat ctattatgga
    17041 ctccgtatta aaaaccccat tttccaacaa aaatatatta agccattcat ttaatggtaa
    17101 aaaatcatta ctcaaaagta gattaattaa tataaaagaa gccgatctga aaaagcagtc
    17161 aaaattaatt ctaattttta tttgtatttt tacttttttt atcatgataa ttcaaagcca
    17221 gtttttaatg gggcaatcct taactgatta taattataaa aagcccttac aaagcgatta
    17281 ccaaatttta gatgaaagta aaaattttgg ttcaaatagt ggatctttcg ttatgtacag
    17341 catgaagaaa gacaaatact atatttataa tgaaaaagaa agtagaaaaa gatattctcc
    17401 tgattcaact tacaaaattt atttagcact gtttggactt gaccgtcata ttataagtga
    17461 taaaaattca cgtatgtcat ggaatcataa acattatctt ttcgagtctt ggaataagga
    17521 acaagattta aatacagcaa tgcaaaattc agttaattgg tacttcgaac gtattagtaa
    17581 tcaaatacca aagaactata ctgcggctca actcaagcaa ttaaattatg gtaatgaaaa
    17641 tttgggaagt tataaaagct attggatgga agatagtttg aaaatatcta atcttgaaca
    17701 agtaatagtt tttaaaaata tgatggaaca aaataaccat tttagtaaaa aagcaaagaa
    17761 tcaattatct tcttcattat tgattaagaa aaatgaaaag tatgaactgt atgggaaaac
    17821 aggtacaggt atagtaaacg ggaagtataa taatgggtgg tttgtaggtt acgtaattac
    17881 aaatcatgat aagtattatt ttgctacaca tttatcagat ggaaacccgt ctgggaaaaa
    17941 tgctgaatta ataagtgaaa aaatattaaa aggaatgggt gttttaaatg accaataagc
    18001 aagttgaaat atctatggct gaatgggatg ttatgaatat aatatgggat aaaaaatcag
    18061 tatcagctaa tgaaattgta gttgaaattc aaaaatataa agaagttagt gataaaacga
    18121 ttagaacatt aatcacaaga ctatataaaa aagagattat aaaacgatac aaatcagaaa
    18181 atatttattt ttactcatca aatattaaag aagacgatat taaaatgaaa actgctaaaa
    18241 cctttcttaa taaactgtat ggaggggata tgaaaagttt agtgctgaat tttgcgaaaa
    18301 atgaagaatt aaataacaaa gaaattgaag aattgcgaga cattttaaat gatattagta
    18361 aaaagtaatt agaggtatgt ttcaaacata atacatatgt aaaccatact tgactcttat
    18421 taaattagtt ttgttaatga catttaaaat atattattaa agatgagagt gtccagaaaa
    18481 taaccatttt ctgtacactc ttgttttttg tctaaataag taagtattac atagaattat
    18541 gtgttcaaaa acccaacaaa aaatctatgt tcacaaaaga cctcgtaatc aagttatggt
    18601 acactaaagg tgtatatagg aggtctgtat tttgaaaata ggttatgcaa gagtttcaac
    18661 tggattacaa aatttgaatt tacaggagga tcgattaaat acatatggtt gtgaaaagat
    18721 atttaatgac catatgagtg gttcaaaaag taagcgacct ggtttagata aagcaattga
    18781 atttgcgagg tcaggagata cgattgttgt ttggagatta gatagactag gacggaacat
    18841 ggaggattta atcacgttag ttaatgaact taacgaacga ggtgtgagtt ttcatagttt
    18901 agaagaaaat ataacgatgg ataaatcaag ttctacagga caattattat ttcatttatt
    18961 cgcagcattt gcagagtttg aacgtaattt aattttagag cgatcatcag ccggtcgaat
    19021 tgcagcacgt gctagaggcc gatatggagg tagacctgaa aaattaaata aacaagattt
    19081 aaacttactt aagacacttt atgataatgg tacgccaatt aaaacaattg cagagcagtg
    19141 gcaagtttca cgtacaacta tttatcgtta tctcaataaa ttagaggcaa aagagaataa
    19201 aaacaagtag agcaactaat ctagcttact ataatgaatc tactaaataa ttttatatat
    19261 cattaacata caaagacttt gattcaatgt cactcgatgt aaaagagacg ttctgacagc
    19321 gtctaaaatc tcataatatt ttcctgttat gagattttaa taataacaca agaaaaaagc
    19381 gtacaaattc gtacgctttt ttaatataat acctgtttca ctaatgaacg ttttaagtat
    19441 cttcatcatt aactgaaact acagtaataa tactcgtcaa caatattagt atagttaaaa
    19501 tagaaagact taggactggc ataaccgaac taaaattata tttgaaatat aaaagtgcta
    19561 atgaagagag aaatgtaaaa ataataaata ccaaagacca tttttctaat ttattcattg
    19621 gcttcacctc tttgaacttt tatataatca taggagatat ttttactacg atttataaaa
    19681 aataagaaga taatcattat taaagaaacg attaatataa tgttgaatcc tatagtatca
    19741 cctaattcgt ttacaccttt gcctaatatc ggagatacaa agctttgtat taataatgaa
    19801 agagatgccc atatagtaaa tgaggttctg ttgcaaagtt gaatttatag tataatttta
    19861 acaaaaagga gtcttctgta tgaactattt cagatataaa caatttaaca aggatgttat
    19921 cactgtagct gttggctact atctaagata tgcattgagt tatcgtgata tatctgaaat
    19981 attaagggaa cgtggtgtaa acgttcatca ttcaacggtc taccgttggg ttcaagaata
    20041 tgccccaatt ttatatcaaa tttggaagaa aaagcataaa aaagcttatt acaaatggcg
    20101 tattgatgag acgtacatca aaataaaagg aaaatggagc tatttatatc gtgccattga
    20161 tgcagaggga catacattag atatttggtt gcgtaagcaa cgagataatc attcagcata
    20221 tgcgtttatc aaacgtctca ttaaacaatt tggtaaacct caaaaggtaa ttacagatca
    20281 ggcaccttca acgaaggtag caatggttaa agtaattaaa gcttttaaac ttaaacctga
    20341 ctgccattgt acatcgaaat atctgaataa cctcattgag caagatcacc gtcatattaa
    20401 agtaagaaag acaaggtatc aaagtatcaa tacagcaaag aatactttaa aaggtattga
    20461 gtgtatttac gctctatata aaaagaaccg caggtctctt cagatctacg gattttcgcc
    20521 atgccacgaa attagcatca tgctagcaag ttaagcgaac actgacatga taaattagtg
    20581 gttagctata tttttttact ttgcaacaga accagcattt gttttaatat ttgttccaaa
    20641 gagccatcat ggctttgaca gagctcttct tctatgcaaa tgcttttaat ccgatccaca
    20701 cgaaaattcc tatattcatt tcttagcctg caaaaccgat taagtaccag ttctgttcat
    20761 aaaaccccag tgatataggc tctatcattc tgctttccgg ttcttgccct cctgatgcag
    20821 gatattgaat tgatattacc cttttattgc agattgcagt ctgaattgct gcaataacgt
    20881 tatccgccaa tgtatttttc tgtccagatg tgctgtacac gttaatactg ttctccaact
    20941 cctgtgcata gtttttttca ccatgcttca aaatagattt gattttatac atagctgaat
    21001 caaaatcctt tataaatgat tcatctccat ggcaatttaa aaatttccct gctgtaatca
    21061 atgcacccac ttccgccgct gtaaacatta ccggcagaag taggaagccc tctacaagaa
    21121 aatatccttt tccggcctca gatccaattg gtattccggc ttcttcaagt gtccggatat
    21181 ctctgtaaac tgtccttaag cttatattaa atcgctgtgc aatttctttg gcaggaatta
    21241 tttttttgat tgcagctgaa taagaataga ggttactctg ttaatcctgt tcaaatttta
    21301 ttcctcctct gtgacttcca taaaaagtat atcctatgcg ttcttaagct agctgctgtt
    21361 agtgcttctc attgcaccct ggttataaaa gccatactca caaacctctt caccaaaact
    21421 ctttacatct ctaatataga actctatcta gcgaactttt agaaaagata taaaacatca
    21481 gagtatggac agttgcggat gtacttcaga aaagattaga tgtctaaaaa gcttgtagtt
    21541 aaagcttttt agacatctaa atctaggtac taaaacaatt catccagtaa aatataatat
    21601 tttattttct cccaatcagg cttgatcccc agtaagtcaa aaaatagctc gacatactgt
    21661 tcttccccga tatcctccct gatcgaccgg acgcagaagg caatgtcata ccacttgtcc
    21721 gccctgccgc ttctcccaag atcaataaag ccacttactt tgccatcttt cacaaagatg
    21781 ttgctgtctc ccaggtcgcc gtgggaaaag acaagttcct cttcgggctt ttccgtcttt
    21841 aaaaaatcat acagctcgcg cggatcttta aatggagtgt cttcttccca gttttcgcaa
    21901 tccacatcgg ccagatcgtt attcagtaag taatccaatt cggctaagcg gctgtctaag
    21961 ctattcgtat agggacaatc cgatatgtcg atggagtgaa agagcctgat gcactccgca
    22021 tacagctcga taatcttttc agggctttgt tcatcttcat actcttccga gcaaaggacg
    22081 ccatcggcct cactcatgag cagattgctc cagccatcat gccgttcaaa gtgcaggacc
    22141 tttggaacag gcagctttcc ttccagccat agcatcatgt ccttttcccg ttccacatca
    22201 taggtggtcc ctttataccg gctgtccgtc atttttaaat ataggttttc attttctccc
    22261 accagcttat ataccttagc aggagacatt ccttccgtat cttttacgca gcggtatttt
    22321 tcgatcagtt ttttcaattc cggtgatatt ctcattttag ccatttatta tttccttcct
    22381 cttttctaca gtatttaaag ataccccaag aagctaatta taacaagacg aactccaatt
    22441 cactgttcct tgcattctaa aaccttaaat accagaaaac agctttttca aagttggcgt
    22501 ataacatagt atcgacggag ccgattttga aaccacaatt atgatagaat ttacaagcta
    22561 taaggttatt gtcctgggtt tcaagcatta gtccatgcaa gtttttatgc tttgcccatt
    22621 ctatagatat attgataagc gcgctgccta tgccttgccc cctgaaatcc ttacatacgg
    22681 cgatatcttc tatataagcg taccggttcc aattttttcg cagtttaact tttccgacgc
    22741 atttatcgtc ttggtagtaa agatatatta tcttatcagt attgtcaata tattcaaggc
    22801 aatctgcctc ctcatcctct tcatcctctt cgtcttggta gctttttaaa tatggcgctt
    22861 catagagtaa ttctgtaaag gtccaattct cgttttcata cctcggtata atcttaccta
    22921 tcacctcaaa tggttcgctg ggtttatcga tatctttcag gtgccctgct ttcatttctg
    22981 taatcactgt tcccgcctct cttctatatc agcggcatat gtgctatcca ggcagccggt
    23041 tttaccagtg tattttttat acatgtccct ggtatatttt gttatattcc tatcatactc
    23101 cggataggca taatgaagcc tttccgccac ctcaccggat accgccctga acaattgatg
    23161 gcatagaaat aatgcttccc atatgttttc ataggaatcc atccggtagg tggacaaaag
    23221 tttctcccac aaatcctcgg atatatacct ttcaataaac ttatagttct tgcctacact
    23281 tcatttaaag cctgtttcga tgccgacctt ccatgatatc attctcagca gctcatggcg
    23341 aacaatctga ttaaaatgat caatagcaaa taaaatttcc ttacggcaca atcctttaat
    23401 aacataaggt gttacattcc aaaattcatt gcagcaatca tcatactccc ttgcgcttgg
    23461 ctttcttaca tgataatcta tatcagtcgg aactatgtcc cttttaattc tacaatcttt
    23521 atcaattaga acctttatta atttatcgcc ctttaggtaa ttatctaact cttccaaggg
    23581 caataaggta agatcaattt tattgtaatc atcaaatagc tataatagat ttagaggtaa
    23641 agaaattaaa tacattgaag agcagaaaga ttttacaaaa gagtatttta ataaaaatga
    23701 tggttctgtt gcaaagtaaa aaatatagct aatcactaat atatcatgtc agtgttcgtt
    23761 taacttgcta gcatgatgct aatttcgtgg catggcgaaa atccgtagat ctgaagagac
    23821 ctgcggttct ttttatatag agcgtaaata cactcaatac cttttaaagt attctttgct
    23881 gtattgatac tttgatacct tgtctttctt actttaatat gacggtgatc ttgctcaatg
    23941 aggttattca gatatttcga tgtacaatgg cagtcaggtt taagtttaaa agctttaatt
    24001 actttaacca ttgctacctt cgttgaaggt gcctgatctg taattacctt ttgaggttta
    24061 ccaaattgtt taatgagacg tttgataaac gcatatgctg aatgattatc tcgttgctta
    24121 cgcaaccaaa tatctaatgt atgtccctct gtatcaatgg cacgatataa atagctccat
    24181 tttcctttta ttttgatata cgtctcatca atacgccatt tgtaataagc ttttttatgc
    24241 tttttcttcc aaatttgata taaaattggg gcatattctt gaacccaacg gtagatcgtt
    24301 gaatgatgaa cgtttacacc acgttctctt aatatttcag atatatcacg atagctcaat
    24361 gcatatctta gatagtagcc aacggctaca gtgataacat ccttgttaaa ttgtttatat
    24421 ctgaaatagt tcatacagaa gactcctttt tgttaaaatt atactataaa ttcaactttg
    24481 caacagaacc tcctaactgt attaccacct taaaagtagt tgcagacgca cttcctaaat
    24541 cgtcagcagt gtttaaccac atatcatcaa caataatcat atgacctgtt gatgatactg
    24601 gagcaaattc tgtcaaccct tcaactacac ctaaaataaa tgctttaatc tgctctataa
    24661 aacccatttt tctcctcctt ttaacttata tcagtttttt taaagtatga gaataatata
    24721 attacactga atatagatgt aacaattatg ataattaaag ataatagaaa tggataagta
    24781 ttaggtaatg ttcctctaga tatgtctcca actgcagccc aaggaaataa tcctctatgt
    24841 tcagaattag cagtcattaa atttatcaaa gtaattatta tggttaaaac aattgtggga
    24901 acataatttt taaaatatat cgacaaaata attattggtg gagataatat ccataataac
    24961 actccgccaa taacaaatgt aaagaatgaa tcaattatta aactctggct taacccttga
    25021 aaatgcaata gcatacctag cattaaagtt agcaaccatg caataacaga tagtgtttga
    25081 atccacaaga ataataatat tattttactt actaaaaaac tttctctaga tataggtata
    25141 attaataagt tttttaaagt atcttctata tattctcttc caaacaaata ggctattata
    25201 accccatata gaggaggtcc aataattagc atatgatata aactgacttc ttcaaataac
    25261 tgtttaaata caatattagg agtcggtact ttcgtccgca tactaataaa agaagctaca
    25321 accaccataa aaggtgctac gcatgtacct aaaatactta ttagaaacat atatgatctt
    25381 tttaacttaa taaattctgt acggagtaga ttatccaatt gtgccacctc ctactaagtc
    25441 ttcgaaataa gtttctagat tatcttctat cactctcatc tggaaaacat caatattgtt
    25501 taatactaat aatctattaa tttcttgttg tctatcaata tgtgaataaa ttttaaattc
    25561 gccattttct ttaattttat agtcataaat tccgaagtta gtttccaaca aacatgcaac
    25621 tttttcttca tctgatactg atatacttat aaattgtctg ttcttttttt ttaaatcttc
    25681 atacataatt tcttctaaca aaactccgtt atgaataata cccaccttgt ctactaactg
    25741 ctctatttct gacaatatat gacttgaaat taaaatggtt atatttctag attgagccag
    25801 atccttaatc aactttctaa tttcttttat gccaatagga tctaatccat tcgtcggctc
    25861 atcaagtatc aataattcgg gattgtgcaa taaagctctc gcaatcccta aacgttgctt
    25921 catacctaaa gaataatttt taaacaattt tactttttca gaagctagtc ctactatttc
    25981 taacacttct tcaattgcat tttctttttg tatacctaat attttagcat ttatagttaa
    26041 gttctcttta gctgtcaaat tactataaaa acctggcgtt tcaaccatag caccaatatt
    26101 ttttaaaatt tcagttttat tactttcgaa ctctttttca aatattttaa tattaccttt
    26161 cgtaggttta attaagccta aaagcattct tatagtagtt gttttgcctg caccatttct
    26221 tcctaaaaaa ccataaattt gtccactttc aacagttata ctcaaattat taactgctat
    26281 ctgacttcca tattgctttg ttaagttatt tatttcaatt atattattca aatttttcac
    26341 ctctggcacc tttcttagtt tgttgttacc tttatcttac gcgcgattag aaaaggctgc
    26401 ctttatctat tcttacaaaa acagccgcta atcttacaaa aatgaaagat tggagttatt
    26461 taaattgaat ggtgaatatt gaaccatcgt ttaatgtaga tgtagcactt actttatggc
    26521 ctaagcgctt tgagattgtg ctgacaatat ataaaccaat accgcttgat ttctcactta
    26581 ttctaccgtt atagcccgag aaacctttat caaagatttt cggtaaatca ctcgcattaa
    26641 tgccgatacc gttatctcgg attgataatt tctttgtatt ttcgtcaaac gtaatccaca
    26701 catctttgcc acgtgcatat tttaatgcat tgtttaatat ttgctcaatc ataattgatg
    26761 cccatttggc atctgttaat ataaccgctt cacttttctc ataatgcaac tttgtttgat
    26821 gatgaataaa ctgtatcgca taacgtttaa tcagtggtcg aattaattca tctacactca
    26881 cttccataaa gaccatgtat gtcttttggt tcatgagttt caaatagttc agtgcaagat
    26941 tcgtgtaatt atcaatttgt aagacttcat tacgcacgtt agaaatcacg tgttcatcag
    27001 gatcttcaag cagtaacttt gatgctgtaa tcggtgtctt gatttgatgc acccacatta
    27061 aaaaatat
//
