LOCUS       NZ_CP062335            20691 bp    DNA     circular CON 13-MAY-2024
DEFINITION  Staphylococcus aureus strain NAS_NP_164 plasmid unnamed, complete
            sequence.
ACCESSION   NZ_CP062335
VERSION     NZ_CP062335.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN15567966
            Assembly: GCF_022404695.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 20691)
  AUTHORS   Cella,E., Sutcliffe,C., Jubair,M., Weatherholtz,R.C., Reid,R.,
            Reid,A., Quay,D., Azarian,T.H. and Hammitt,L.
  TITLE     Carriage prevalence and genomic epidemiology of Staphylococcus
            aureus among Native Americans in the southwest US
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 20691)
  AUTHORS   Cella,E., Sutcliffe,C., Jubair,M., Weatherholtz,R.C., Reid,R.,
            Reid,A., Quay,D., Azarian,T.H. and Hammitt,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-JUL-2020) Burnett School of Biomedical Sciences,
            University of central Florida, 4111 Libra Dr, Orlando, FL 32816, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2020
            Assembly Method                   :: Uniclycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50x
            Sequencing Technology             :: Illumina MiSeq; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022404695.1-RS_2024_05_13
            Annotation Date                   :: 05/13/2024 03:55:53
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,807
            CDSs (total)                      :: 2,726
            Genes (coding)                    :: 2,648
            CDSs (with protein)               :: 2,648
            Genes (RNA)                       :: 81
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 48 of 78
            Pseudo Genes (incomplete)         :: 34 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 22 of 78
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP062335.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..20691
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="NAS_NP_164"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed"
                     /collected_by="UCF"
     gene            166..812
                     /locus_tag="IF749_RS13880"
                     /old_locus_tag="IF749_13845"
                     /pseudo=""
     CDS             166..812
                     /locus_tag="IF749_RS13880"
                     /old_locus_tag="IF749_13845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            <823..1105
                     /locus_tag="IF749_RS13885"
                     /pseudo=""
     CDS             <823..1105
                     /locus_tag="IF749_RS13885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            2317..2934
                     /gene="cadD"
                     /locus_tag="IF749_RS13890"
                     /old_locus_tag="IF749_13850"
     ARG             2318..2931
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="99.51"
                     /coverage="100.0"
     gene            2953..3300
                     /locus_tag="IF749_RS13895"
                     /old_locus_tag="IF749_13855"
     CDS             2953..3300
                     /locus_tag="IF749_RS13895"
                     /old_locus_tag="IF749_13855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119691.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNQEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            3460..3552
                     /locus_tag="IF749_RS13900"
                     /old_locus_tag="IF749_13860"
     CDS             3460..3552
                     /locus_tag="IF749_RS13900"
                     /old_locus_tag="IF749_13860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            3764..4318
                     /locus_tag="IF749_RS13905"
                     /old_locus_tag="IF749_13865"
     CDS             3764..4318
                     /locus_tag="IF749_RS13905"
                     /old_locus_tag="IF749_13865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="WP_001808186.1"
                     /translation="MSNTKIKYQIFISSTYLDLIEERQAVVEAVLNSNNIPAGMELFNS
                     SSKSQWEIITQWINESDAVILLLGSSYGTIDSEENISYTEMEYNFAKSLGKPIYVFEMN
                     KASTESAEKSKKLDEFKTKVKENRLISPNINDISELKSKVSQTLMQSVPSEIKENSGWI
                     RVQDCGKNVKKLKNWMLYKEI"
                     /name="DUF4062 domain-containing protein"
     gene            4333..4737
                     /locus_tag="IF749_RS13910"
                     /old_locus_tag="IF749_13870"
     CDS             4333..4737
                     /locus_tag="IF749_RS13910"
                     /old_locus_tag="IF749_13870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_106669568.1"
                     /translation="MKEELYKIFMYVKTFYFQHTPFDDSYIEDIENYLLNYENNPHKSF
                     MKIKVYDYKNFLKHLKNILILIKQGKKPLAQAGHFKLSFYEEDLKLLQKNYKTTLVDIK
                     GLNKHFYKECDRCLKAYNIFIEGINKHLYE"
                     /name="hypothetical protein"
     gene            complement(4857..5672)
                     /locus_tag="IF749_RS13915"
                     /old_locus_tag="IF749_13875"
     CDS             complement(4857..5672)
                     /locus_tag="IF749_RS13915"
                     /old_locus_tag="IF749_13875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000164958.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYNAPAEKQTKLRNDLYSITAIIDL
                     GQKLHVVNKYGHEHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            complement(5665..7108)
                     /locus_tag="IF749_RS13920"
                     /old_locus_tag="IF749_13880"
                     /pseudo=""
     CDS             complement(5665..7108)
                     /locus_tag="IF749_RS13920"
                     /old_locus_tag="IF749_13880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Mu transposase C-terminal domain-containing
                     protein"
                     /name="Mu transposase C-terminal domain-containing protein"
     gene            complement(7080..7673)
                     /locus_tag="IF749_RS13925"
                     /old_locus_tag="IF749_13885"
     CDS             complement(7080..7673)
                     /locus_tag="IF749_RS13925"
                     /old_locus_tag="IF749_13885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690638.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            complement(7937..8317)
                     /gene="blaI"
                     /locus_tag="IF749_RS13930"
                     /old_locus_tag="IF749_13890"
     ARG             complement(7941..8317)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            complement(8307..10064)
                     /gene="blaR1"
                     /locus_tag="IF749_RS13935"
                     /old_locus_tag="IF749_13895"
     ARG             complement(8311..10064)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.56"
                     /coverage="100.0"
     gene            10171..11016
                     /gene="blaZ"
                     /locus_tag="IF749_RS13940"
                     /old_locus_tag="IF749_13900"
     ARG             10172..11013
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            11385..11993
                     /locus_tag="IF749_RS13945"
                     /old_locus_tag="IF749_13905"
     CDS             11385..11993
                     /locus_tag="IF749_RS13945"
                     /old_locus_tag="IF749_13905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002436987.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001566953.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGKSIENRPV
                     LQEALNFLRMGDRFVVESIDCLGRNYDEVIHTVNYLKDKEVQLMITSLPMMNEVVGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGQSISKIAKEVNITRQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            12407..12700
                     /locus_tag="IF749_RS13950"
                     /old_locus_tag="IF749_13910"
     CDS             12407..12700
                     /locus_tag="IF749_RS13950"
                     /old_locus_tag="IF749_13910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WP_000726502.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            12775..14709
                     /locus_tag="IF749_RS13955"
                     /old_locus_tag="IF749_13915"
     CDS             12775..14709
                     /locus_tag="IF749_RS13955"
                     /old_locus_tag="IF749_13915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WP_000713729.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTAIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLILKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTLDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            14713..15024
                     /locus_tag="IF749_RS13960"
                     /old_locus_tag="IF749_13920"
     CDS             14713..15024
                     /locus_tag="IF749_RS13960"
                     /old_locus_tag="IF749_13920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WP_000831610.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            15036..15662
                     /locus_tag="IF749_RS13965"
                     /old_locus_tag="IF749_13925"
     CDS             15036..15662
                     /locus_tag="IF749_RS13965"
                     /old_locus_tag="IF749_13925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000593103.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            15900..16529
                     /gene="mobV"
                     /locus_tag="IF749_RS13970"
                     /pseudo=""
     CDS             15900..16529
                     /gene="mobV"
                     /locus_tag="IF749_RS13970"
                     /inference="COORDINATES: protein motif:HMM:NF013258.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            16623..17168
                     /locus_tag="IF749_RS13975"
                     /old_locus_tag="IF749_13940"
     CDS             16623..17168
                     /locus_tag="IF749_RS13975"
                     /old_locus_tag="IF749_13940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001805533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000273005.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTDFEKYTKQIKAAQMILD
                     DYECIKSGKSLKKAEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQEREIIFKEDREDGYTL"
                     /name="hypothetical protein"
     gene            17552..18412
                     /locus_tag="IF749_RS13980"
                     /old_locus_tag="IF749_13945"
     CDS             17552..18412
                     /locus_tag="IF749_RS13980"
                     /old_locus_tag="IF749_13945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000145511.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            18499..18840
                     /locus_tag="IF749_RS13985"
                     /old_locus_tag="IF749_13950"
     CDS             18499..18840
                     /locus_tag="IF749_RS13985"
                     /old_locus_tag="IF749_13950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000761341.1"
                     /translation="MKLAEAIKEQRELKGWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRVPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(19079..19150)
                     /locus_tag="IF749_RS13990"
                     /old_locus_tag="IF749_13955"
     CDS             complement(19079..19150)
                     /locus_tag="IF749_RS13990"
                     /old_locus_tag="IF749_13955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_106873653.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGY"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            19299..19484
                     /locus_tag="IF749_RS13995"
                     /old_locus_tag="IF749_13960"
     CDS             19299..19484
                     /locus_tag="IF749_RS13995"
                     /old_locus_tag="IF749_13960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466619.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSVWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            complement(19703..20446)
                     /locus_tag="IF749_RS14000"
                     /old_locus_tag="IF749_13965"
     CDS             complement(19703..20446)
                     /locus_tag="IF749_RS14000"
                     /old_locus_tag="IF749_13965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843758.1"
                     /translation="MKSVKRLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESATEDKQKKESDNINFESKSDAQIVEILKNQINTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNAR
                     QNVDAQEKTYTTSPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAQREDVSANPND
                     NDSDIEEKSEETEPKKGFWSRLFGN"
                     /name="DUF536 domain-containing protein"
     ARG             10172..11016
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     BGC             7407..17700
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          1163..1310
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.333"
                     /coverage="100.0"
                     /evalue="2.96e-25"
     Typing          17553..18412
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(19704..20446)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          15901..16175
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="94.565"
                     /coverage="100.0"
                     /evalue="4.71e-46"
ORIGIN
        1 ttggtaataa aacgtttaga aactgtttat ttatataatt ttcgatactt agattatata
       61 atgaataata tcttagtgca agcacctaga ttattaaata aacacaaaaa atgtaagcgt
      121 tttattacct cttaccaaac taaaattcgg aaagaggttt ttattatgtc aattaaactt
      181 tacaacataa atgaggaata cagagaaaag ttttatcaaa taccgaaagt attttttaca
      241 aatcctaaat atatcaagtt atccaatgat gcaaaaatgg catggggtat tcttagagat
      301 cgtttagatt tatcaattaa aaatggttgg gttgattcta aaacaggtaa tatttatttt
      361 tattacaaaa atgaaaaccc acaaaatata ttaaattgta aaaaagataa agtaattaaa
      421 ataaagaaag aacttaattg aagccgaatt actactacaa gaaagacaag gtttaaataa
      481 gacaaataaa ctttatttag ttaaaccaga agtaacagaa gatgatattt ataaaattca
      541 aaagcaagaa aacactgttg agagcagcaa tggcaaggaa gtcggaaaaa ccgacttcaa
      601 gaagtcgata aaacagaatc taacaatact gaaataaatg atatgaatga cttgaatgat
      661 atagagtccg aaaatgaaat tagtaatcat tcaagtcaat gcaaggttat ttaatgcaaa
      721 caattttaac tgaatttgaa gaaacacatg cactttatat gcgccgtaaa aacatgaaac
      781 aatataatat ctttaatcaa tcattcaaat gattttataa caatcaaaga tacatcaaaa
      841 tatttcgtta aatcatctga ctttttaact gatagcgatg aaaaaatcaa gaaattgtca
      901 gtgatctaga aaaagatttg tatcgaaaac gtatgttaag ttatggtgga ttgcttaaat
      961 aaaaacataa aattttaaac ttagacgatg ctgaagatgg caatttaatt aatacaagtg
     1021 atgaagataa aatagcaaat gaagaagaaa aggcacattc gattacggca attttgaaaa
     1081 gcaaaattat tatttaaggc attagtgata actgatgtct ttttttatta cttttttgta
     1141 aaaaaagtgc tgtcttattt ttgtgacaaa tgctgtatgt agtgtcacaa aagtgtgaca
     1201 cttgagcttt ttatgacccc acacaaaaac attttcgaag ccttgaaata tctggctttg
     1261 ccagatcccc cattcattga tggggacaaa tttcccttat gctcttacgg agattttaga
     1321 gttaaattaa aatttctaag tttttgataa gaaaagccct gcaggaattt agaagaacgt
     1381 ggggaagttt taaagaattt tatgctaatt tttaatttgc atgtaaatgg gcagtgtcta
     1441 aaaaatagtt attgtttttg ctcaaatttt tgtttttgaa aatagcatat atttatttgg
     1501 ctcatatttg cgttttaaaa gcgtatataa gttttagata taaaactata tgaatcaccc
     1561 ctaaatcttt aaaatgccct cttaaaattc aaaataaggg cataaaaaat aaaagccccc
     1621 cccagataaa gtgaggtagc tttttctttc gacgccgtat cgtcgatgta attcaaaaaa
     1681 gttatgggct ataaatctac atcacttttt caagaatgta gtagcaatat tcaacgcaaa
     1741 ttaattttta taactgctcg gaatatctca agccgtttct ttaattttga aataaaaaaa
     1801 tcgacgaagg tcgattacgt ttttgcacat gtcgatttat ccgacgtata agtgcgccct
     1861 tacgggattt aactagatta taacgacgaa ttttagacct gtaaagcaat aacaattagg
     1921 tctaccaggt agataaagtg tacaaagtag aaccgaaaaa gttatttatt ttgaagattt
     1981 ttcgtagata taatttgcta ataaacttcc taaaactgaa taaagaaaaa tagttaaact
     2041 catgtaatca ctccataatt ctgaagtgtc tccatgtcta cgcatagaca cgcatttatg
     2101 ccgagaaaat ttattgtgcg ttgagaagaa cccttaacta aacttgcaga cgaatgtcgg
     2161 catagcgtga gctattaagc cgaccattcg acaagttttg ggattgttaa gggttccgag
     2221 gctcaacgtc aataaagcaa ttggaataaa gcacctatga ttatttaaaa atataagtta
     2281 taatacattc aaaaatattt ttgaatgagg tgtattatga ttcaaacggt tgttgctgct
     2341 gctgttcttt atattgctac agcagttgat ttattagtaa ttttattaat attttttgct
     2401 agagcaaaga ctagaaaaga atatagaaat atttatgttg gtcaatattt agggtctatt
     2461 attttaatat tagttagttt gtttttagct tttgtattaa attatgttcc agaaaagtgg
     2521 atattaggtt tattgggttt aataccaatt tatcttggaa ttaaagtggc tatttatgat
     2581 gattgtgaag gagaaaagag agctaaaaaa gaattgaatg aaaaaggatt gtctaaatta
     2641 gttggtacgg ttgcaattgt tacgatagca agttgtggcg ccgataatat tggtttattt
     2701 gttccgtatt ttgtgacatt aagtgttact aatttattac ttactctgtt tgtcttttta
     2761 attttaattt tcttcttggt gtttactgca caaaaattag ctaatatccc aggaattgga
     2821 gaaattgttg agaaatttag tcgttggatt atggctatca tttatatagc tttaggttta
     2881 tttattatta ttgaaaatga cactattcaa acaattttag gatttatatt ttaatttagg
     2941 gtgtgatttt atatgagtta tgaaaatact tgtgatgtga tctgtgtaca tgaggataaa
     3001 gttaacaatg ctttaagttt tttagaagat gataaatcta agaaattact taacatttta
     3061 gaaaaaattt gtgatgagaa gaaattgaaa atcatattat ctttgattaa agaagatgag
     3121 ttgtgtgttt gtgatatttc tttgatattg aaaatgagtg ttgcttcaac ttcacatcat
     3181 ttaaggcttt tatataaaaa tgaggtactt gatttttata aagatggaaa gatggcatat
     3241 tattttatta aagacgatga aataagagag tttttctcta aaaatcagga gggtttttga
     3301 aacgagtttc ttcttgtctt gatactataa aaaacaaagt tatataacat aagacgactt
     3361 atcggaagtt atctatcatc gtatattcgg agatgatata atatacaggt cgcctatctc
     3421 tcaggcgtca attcagacgc agagaggagg tgcattactt tgctaatcat tttcgttcac
     3481 atcatagcac cagtcatcag tggctgtgct gttgcgtatt atacttattg gcttagtaaa
     3541 cgcaacaaat aattaatagg cgactttata agccagcatc gaaaaaatcc ccacactatt
     3601 gcagtagtgt ggggattggt gcattaattg ttaatcattt tcgttatcta gattataaca
     3661 ctggttagta gaggaatgca aaaagataat attttaagta gtctttttgg atattatcat
     3721 atgatatatt tatgtaaatt gattttttat taaaggagca tatatgagta atactaaaat
     3781 taaatatcaa atttttattt catcaactta tttagattta atagaagagc gtcaagcagt
     3841 agtagaagca gttttaaaca gtaataatat tccagcaggt atggaacttt ttaactcaag
     3901 tagtaaaagc caatgggaaa taataacaca atggatcaat gaatcagatg cagtgatatt
     3961 attgttaggt tctagttatg gaacaattga tagtgaagaa aatattagct atacagaaat
     4021 ggagtacaat tttgctaaat ctttaggtaa acctatatat gtttttgaga tgaataaagc
     4081 atctaccgaa tccgcggaaa agtctaaaaa attagatgag tttaagacaa aagttaaaga
     4141 aaatagacta attagtccaa atattaatga tatttcggaa ttaaaaagta aagtatctca
     4201 gactttaatg caaagtgtac ctagtgaaat taaagaaaat agtggatgga taagagtaca
     4261 ggattgtggt aaaaatgtaa aaaaattaaa aaattggatg ctatacaaag agatttagat
     4321 acatatgatt ttttgaaaga agaactttat aaaatattca tgtatgtaaa aactttttat
     4381 ttccagcaca caccatttga tgatagttat attgaagata tagaaaacta cctgctaaat
     4441 tatgaaaata atccacataa atcattcatg aaaataaaag tttatgatta taaaaacttt
     4501 ttaaaacatt taaaaaacat attgatttta attaaacaag gaaaaaagcc attagctcaa
     4561 gccggtcatt ttaaattaag cttttacgaa gaggatttaa aattgttaca aaaaaattat
     4621 aagactacgc tagtcgatat taaaggattg aataaacatt tttataagga atgtgatagg
     4681 tgcttaaaag catataatat ttttattgag ggtataaata aacatttata tgaatgatat
     4741 aagtacaccc taatcataca tatataattg ttgtcacttt actcgatata tgagaatgac
     4801 tttacctaat aaatgagaaa agcaacgcac tatattaaaa tgcgttgctt tttctattat
     4861 cgaataccta taactaaact atctctagct gtttctacaa cttctgtact tattttatct
     4921 aaaccattta tatccataat tctgtctatc tgcgcaaata aacgatgaat cagcctaaaa
     4981 ttcccttttg taattttaat aatcgtcgtt attgcctcat aatcagtaaa gtcttcgagt
     5041 tttaaatcaa atcctaagtc ttgccactta tattctaata tatgatgcgt ctcatcttta
     5101 cttagattat caaattcatg cgcaaaacct atacgcgaat atagttgagg ataacgagat
     5161 agttttttct ctatacccgg cataccaata aatatcattg ctaaattatg ttcatcataa
     5221 atagctctta attgctctaa atgttgcact ttaaggcgat caatctcatc tactataatt
     5281 aaatcaatat atttaaacat atcactataa tgtttactat gttcatgtcc atacttattt
     5341 acaacatgta atttttgacc caaatcaatg attgcagtaa tactatataa atcattcctt
     5401 aatttagttt gtttttctgc tggtgcatta taaaatattt tatccaccga tagtatgtca
     5461 tcggtcgttt tactagctaa atcttcccaa cctctatggt taacttgttt ttcaatagta
     5521 tcccaatttg tgtaatacct agacgataaa gtttttccga caccaggttg accataacat
     5581 ataccaatat actgatattt aatacaagca tcacaaaatt cagcaaagcg tttatactct
     5641 ttcgtttcaa tgaaattttg atttttagtc attacgatat ctctttaatt ttttgacgtt
     5701 tttagtcgtt tcttgaggtg aataaccaca atttttttct tccttaatta attccgtggt
     5761 acttggacta gcaatatttt gttttaagtg ttttcttctc tgactacgag cgtgctgtat
     5821 gtcttttata tctatggagt aatcagctat ttctggacat atagcagtac aaagaaattc
     5881 atctctataa aacacacgta tttcagccat atcatttggg ttataacgaa tcagtacata
     5941 ttcacctaca taagcttcta gattagtatt actgtatcga aaaccttgaa aatgaatgcc
     6001 atctgaatga acttttctag atttaggtat ttccaacaat aataaatcaa gttgttctaa
     6061 gctacttggc atattaggga aaaagtgatt actattccaa tgactgatag gcgtggtatg
     6121 aatagtacta tgttcttttt gattataatc ttcaattaaa aagtaacgta atttttcttc
     6181 aaaattgtga aaatttatta gattactagg agtatcatta ttgtttatat atccaggcag
     6241 ttgttctaag aaagtttgat taactgtctg aaagaatcgt tctatttttc cacgaccacg
     6301 aggaacacca actttcgaaa acatcaagtt aattttcaaa tcaatagcga cttgttccat
     6361 atgatgtgaa gtaaagtcac ttccatgatc tgtgtagaat ttttcgggta taccacacac
     6421 tggccaattg gtatcatttt tattccatat tgcttggtgt agtgttaatg ctgtgttttg
     6481 agcattgggg ggcatcaaaa cttaagaaat agcctgcaat tgcacgacta tagtcatcca
     6541 taataatagt tagccatggt ctattgatat tacctttttg gtctaatata aagatatcta
     6601 gcaaagtatg gtctgcttgc catatttcat tgggtctcga ggattctcta atttgtatta
     6661 aatcgtactt attttgatag tatttttcac cctgatgaga gaaatcaata acagacttag
     6721 gcatcgcttt aataacacta taaatttgtt tataacttgg tatatcaaaa ttattttctt
     6781 tacagtaatt agtgattttc ctatgaattg tggctatact atttctttta ttcataagcg
     6841 caaggcgttc aatttcatca attatctttg gttctatttt acgtgttcct ttatcagctc
     6901 ttgtcgcata gattagtcct ttaagtcctt gttctttata tgacttattc cacctataaa
     6961 gggtgcttaa cgcaatccct ttacttttag aaatacttga taaagattgt tcgcctagga
     7021 taaaaggttt tataatattg tacttttgag tagctttttt acgtttggct tcagaaaaat
     7081 tagttagata cttctccttg tttttcatct tccttgtcct ccaatttatt gaggtaacga
     7141 taaattgttg tacgtgaaac atgccactgt tctgcaattg tcttaattgg cgtgccatta
     7201 tcataaaggg tcttaagtaa gtttaaatct ttttgattta atttttctgg tctgcctcca
     7261 tatcggcctc tagcacgtgc tgcaattcgg ccagctgaag aacgctctaa aattaaatta
     7321 cgttcaaatt ctgcaaatgc tgcgaataaa tgaaataata attgtccagt tgaacttgat
     7381 ttatccattg ttatattttc ttctaaacta tggaaactta cacctcgttc gttaagctca
     7441 ttaactaatg tgattaaatc ctccatatta cgtcccaatc tatctaatct ccaaacaaca
     7501 atcgtatctc ctgacctcgc aaattcaatt gctttatcta aaccaggtct tttacttttt
     7561 gaaccactca tatggtcatt aaatatcttt tcacaaccat atgtatttaa tcgatcctcc
     7621 tgtaaattta aattttgtaa tccagttgaa actcttgcat aacctatttt caaaatacaa
     7681 acctcctata tacatcttca gtgtaccata acttaattac aaggtctttt atgaacatag
     7741 attttttgtt gggtttttga acacataatc ctatgtaatt cttacttatt tagacataaa
     7801 agaagagtgt acagaaaatg gttattttct gtacactctc atctttaata atatatttta
     7861 aatgtcatta acaaaactaa tttaataaga gtcaagcata gtttacatat gtattatgtt
     7921 tgaaacatac ctctaattac tttttactaa tatcatttaa aatatctcgc aattcttcaa
     7981 tttctttgtt atttaattct tcatttttcg caaaattcaa cactaaactt ttcatatccc
     8041 ctccatacag tttattaaga aaggttttag cagttttcat tttaatatcg tcttctttaa
     8101 tatttgatga gtaaaaataa atattttctg atttgtatcg ttttataatc tcttttttat
     8161 atagtcttgt gattaatgtt ctaatcgttt tatcactaac ttctttatat ttttgaattt
     8221 caactacaat ttcattagct gatactgatt ttttatccca tattatattc ataacatccc
     8281 attcagccat agatatttca acttgcttat tggccattta aaacacccat tccttttaat
     8341 attttttcac ttattaattc agcatttttc ccagacgggt ttccatctga taaatgtgta
     8401 gcaaaataat acttatcatg atttgtaatt acgtaaccta caaaccaccc attattatac
     8461 ttcccgttta ctatacctgt acctgttttc ccatacagtt catacttttc atttttctta
     8521 atcaataatg aagaagataa ttgattcttt gcttttttac taaaatggtt attttgttcc
     8581 atcatatttt taaaaactat tacttgttca agattagata ttttcaaact atcttccatc
     8641 caatagcttt tataacttcc caaattttca ttaccataat ttaattgctt gagttgagcc
     8701 gcagtatagt tctttggtat ttgattacta atacgttcga agtaccaatt aactgaattt
     8761 tgcattgctg tatttaaatc ttgttcctta ttccaagact cgaaaagata atgtttatga
     8821 ttccatgaca tacgtgaatt tttatcactt ataatatgac ggtcaagtcc aaacagtgct
     8881 aaataaattt tgtaagttga atcaggagaa tatctttttc tactttcttt ttcattataa
     8941 atatagtatt tgtctttctt catgctgtac ataacgaaag atccactatt tgaaccaaaa
     9001 tttttacttt catctaaaat ttggtaatcg ctttgtaagg gctttttata attataatca
     9061 gttaaggatt gccccattaa aaactggctt tgaattatca tgataaaaaa agtaaaaata
     9121 caaataaaaa ttagaattaa ttttgactgc tttttcagat cggcttcttt tatattaatt
     9181 aatctatttt tgagtaatga ttttttacca ttaaatgaat ggcttaatat atttttgttg
     9241 aaaaatgagg tttttaatac ggagtccata atagattccg cataagtttt aaattcattt
     9301 ttgttaatat tattaaggac aaatctatcg gcttctactt cattgtcatg aattatcttt
     9361 ctttttacaa tatgtactaa tggattgtaa ctcataataa tagagaagat attaaagata
     9421 attaaatgta aagtatctct atttttagca tgagcatatt catgcagtat tatatatttt
     9481 agtcttttat caattacact tttaaaatat gaactaggaa tcaaaataat atatttccca
     9541 taccaaaaag ttattggaga ttgaatagcc tctgcttttc gaatcacaat atttttttta
     9601 tattgatggt tgaaaagtat cgtatctatt ttattttttt cattttcgtt tagataaagt
     9661 gactgtttct ttaaatattt aagatataat aaggctttca aaaatttaaa acttaaaata
     9721 ataactaaaa ctatccaaat aactgtgcag atattatcaa ttgaatccca attaaactta
     9781 tggatatctg ttgcgaactc ttgaacaggt ttggtggtaa ttatgttatg gttcaagtcg
     9841 tgtgacttac tttcaactgt gggcgcttga ttattcacat tattaaattt tataaaagag
     9901 aatttaattg ggataaaagg aattaatcca gcaagcacag ttagatacca aactttataa
     9961 tttaaactat aattaaaata gcgttttaat atgtacctaa aaaatactaa caatagaaat
    10021 ataaaacaaa agcttactac actcattatt agtaatttag ccattttgac accttctttc
    10081 aaatatttat aataaacaat tgacatcaat attacaattg taatattatt gttttgtaaa
    10141 aattacaact gtaatatcgg agggtttatt ttgaaaaagt taatattttt aattgtaatg
    10201 gctttagttt taagtgcatg taattcaaac agttcacatg ccaaagagtt aaatgattta
    10261 gaaaaaaaat ataatgctca tattggtgtt tatgctttag atactaaaag tggtaaggaa
    10321 gtaaaattta attcagataa gagatttgcc tatgcttcga cttcaaaagc gataaatagt
    10381 gctattttgt tagaacaagt accttataat aagttaaata aaaaagtaca tattaacaaa
    10441 gatgatatag ttgcttattc tcctatttta gaaaaatatg taggaaaaga catcacttta
    10501 aaagaactta ttgaggcttc aatgacatat agtgataata cagcaaacaa taaaattata
    10561 aaagaaatcg gtggaatcaa aaaagttaaa caacgtctaa aagaactagg agataaagta
    10621 acaaatccag ttagatatga gatagaatta aattactatt cgccaaagag caaaaaagat
    10681 acttcaacgc ctgctgcttt cggcaagact ttaaataaac ttatcgcaaa tggaaaatta
    10741 agcaaaaaaa ataaaaattt cttacttgat ttaatgttta ataataaaaa cggagacact
    10801 ttaattaaag atggtgttcc aaaagactat aaggttgctg ataaaagtgg tcaagcaata
    10861 acatatgctt ctagaaatga tgttgctttt gtttatccta agggccaatc tgaacctatt
    10921 gttttagtca tttttacgaa taaagacaat aaaagtgata agccaaatga taagttgata
    10981 agtgaaaccg ccaagagtgt aatgaaggaa ttttaatatt ctaaatgcat aataaatact
    11041 gataacatct tatagtttgt attatatttt ctattatcgt tgacatgtat aattttgata
    11101 tcaaaacctg attttccctt tattattttc gagatttatt ttcttaattc tctttaacaa
    11161 actagaaata ttgtatatac aaaaaatcat aaataataga tgaatagttt aattataggt
    11221 gttcatcaat cgaaaaagca acgtatctta tttaaagtgc gttgcttttt tctcatttat
    11281 aaggttaaat aattctcata tatcaagcaa agtgacataa ttgttgaatt tatagtaact
    11341 gaaacgtatg attagggtgt atattaatta tgagatggaa atcaatgatt gttggctatg
    11401 cgagagtatc atcgaacgat caaaatttag aaagacaact tgaaaattta aagacgtttt
    11461 gtgctgaaaa aatatttaca gaaaaacagt ctgggaaatc tattgaaaat agaccagtac
    11521 ttcaagaagc acttaacttt ttgaggatgg gagatcggtt tgtagtagaa tccattgatt
    11581 gtttaggtcg taattatgat gaagtgattc ataccgttaa ttatttaaaa gacaaagaag
    11641 tacaattaat gattactagc ttacctatga tgaatgaagt ggttggcaat ccattactgg
    11701 ataagtttat gaaagattta attattcaaa tattagcaat ggtttcagaa caagagagaa
    11761 atgaaagtaa acgtcgacaa gcgcaaggaa ttcaagttgc gaaggaaaaa ggcgtatata
    11821 aagggcgccc cttactttat tcaccaaatg ctaaagatcc acagaaacgt attatttatc
    11881 atcgcgttgt agaaatgtta gaagaaggcc aatcaattag taaaattgcg aaagaagtaa
    11941 atataacaag gcagacgatt tacagaatta aaaacgataa tgatttgatt taataaactt
    12001 tgtttcaatg caactgagag cttctcacag cgtctcaaaa cagatgatta taatctatta
    12061 tgagttttta ataataagac aagaaaagag agcgtaaata tgctctctct ttttctcatt
    12121 aacgaatgtt tataacgcaa tcatgatgag agtattaata cagttaatta tttgaaatac
    12181 tttagtttat ataatgttga attataggta gtgaaattgt atttattata cattgtcata
    12241 tcgttgttta atgatagtta atttaaggat aatagaatta atattatata tagatgaaca
    12301 aaacaagcaa cagagcagaa aaaacacttt tagattattt ttactcattc tctattttat
    12361 ttatttttgc tataataaat aaagaatatt aaatgtaggt gtttttatga aaaagaaatt
    12421 tgtttctagt tgtattgcta gtacaatctt attcggcact ttattaggtg taacttataa
    12481 agctgaagct gcaacagtac atgtagctgg tggtgtttgg agccatggta ttggaaaaca
    12541 ttacgtatgg tcttattata gtcacaataa aagaaatcat ggttcaacag cagtagggaa
    12601 atattcatct tttagtggtg ttgctcgacc tggtgttcaa tctaaggcat ctgctccaaa
    12661 ggcttggggt ggaaacaaaa cattttatag tcttcactaa ttacatatat taattaagga
    12721 gaatagacag aattaagtaa acttaattct gtctattctc ttgaaagagg caatatgaaa
    12781 aaattcaaat tatttttaga ttttagtact ttattattaa tttcagggct attattttta
    12841 tttttcttca aagaaaatga agaaattata cctgaaagtt ccaatatttt aacaatctct
    12901 aattgggata aatctaacag taaatcaaaa gtgttagatg tcattgaatc aggcgccaaa
    12961 aatcaaaata tacaaataat taaatccgtt aaagattttg ataataaaaa agaatttttt
    13021 gttttcaact caaaacgaaa taattctgac tttatacgta ataaaacatc acttttaact
    13081 ccatcagatt tattaaacag agagataaaa ggaaagtatt atattattgg tgaacatttc
    13141 aatgtagaag agcttacgag tgaattaaaa aaagctggtt taacatctga agttgaatac
    13201 ataaatagaa acatattatt ttttgaatta gtcatagata atgatttatt agtgcctttc
    13261 atattcttag gcgtattata tcttttgtac ttcttatatg acagaggata taatttgaaa
    13321 ttttatgcta ttcaaaagct acatggcttt tcaactacac gcattatttt tcataatatt
    13381 catataaaaa tcatttattg gctagtactt accgctattt tctttattgc taatatatta
    13441 atcattcata tagccaattt agaattggat ttcttaatgt ttattcgtag atttatcgtg
    13501 ttgctttttg tttttgcttg tattactaca ttgctgtggc tgatttcgta tagtcttctt
    13561 ttgaagttaa gtattccatt aatcttaaaa gggaaaaaag gatataagtt ttcaatattt
    13621 atgggtacct tcaccaaatg tatcatggtg ctaatactat cttttttact ggcacaaaat
    13681 ttaaatgctt atacgaagtt aaagaatata tatgactctg aaaaaatctg gcaaaagtta
    13741 gataattact atacattaga gatttctcct aatattagaa attcagaaga aaaacaaatt
    13801 ttagaaacta atatatacaa tttaattaag aaaagcgaac aacttggtgg attgctttta
    13861 aagaataata atatagccaa tcccgataaa aacaattaca ttcctgaaaa tggcaatgtc
    13921 ttttttatca ataacaattt tctgaatttc tataaaaata taaatcatga ttttaaaatg
    13981 attgacaatc attcggataa aataaacgtg tttattcctc caaggttaca atatcaaaaa
    14041 tctgaaattc aaaaaaatca ccaaggatgg attgactttc aaaagcaaca aaacaaaaaa
    14101 gtagatgtgc aagtactgtc aaaaaacgta tctgtttttt cttttgatcg cacaactaat
    14161 ttgaaatttg ggtatctaga ttctccaata gtaatgttgt tgacacttga cgatttaaca
    14221 ggagattttt atttagctgc tgtttctcaa ggtggatatc tatttaaaga tttagataca
    14281 cttaaacagt tgcttaaaga taatcaccta gaagaagaaa ttagcggtat aactaattac
    14341 aaggattctg tgttaaatga attaaatgaa acgaaaacaa aaatgataat aacaatagtt
    14401 actattatta ttaacgtttt cattcttttg atagctactg tatttgaaac aattcaatat
    14461 tttagctgga ataaaaagca actattatta agaaaaattc atggttattc attattcagc
    14521 agtaatgtac gttatttaac aatttctatc ttactttcta ttatgttagc ttacactacg
    14581 catattttat ttggttcaaa gatattacta ttcataataa tgtctattgc tattattcaa
    14641 catttacttc aaattgctta tattaaatat cttgaaaaat actttaaaga tttaatgagg
    14701 gagatttaaa caatgaaaag aactttaatt attgtaacaa ttgtactatt aatcatcata
    14761 cttagtctgt tattggttag aaatgagcat ttagatcgtt ttaacccact gttaaaagaa
    14821 aaagtatctt atgccaaagt tccaaaagat acccaggact atagaaatat aactgtatac
    14881 tctaaaaatg gagaaaaaaa gagttataaa ttggattttt taggttatga tcctacaaaa
    14941 gaatatgtga aagtaaatca taaagggaaa tatgtgcgtt cgatagaata cattacaaaa
    15001 gatattccta gctttttaaa atgaggtgac cgatagtgat aaaacttgaa aatgtttttg
    15061 taaaaaaagg taataaaaac attttagacg gatgtaactt taattttgaa aaaggaaaat
    15121 catatgcttt agttggagaa agtggcgctg gaaaatctac tttacttaac ataatcgctg
    15181 ggttcgaaga tgtatcacaa ggaagcatat atattgaaga taagttacta aaaaagaaag
    15241 tcgattttta tagatatacg ttagggtatt tgtttcaaaa ttttgcttta cttgaaaatc
    15301 aaacaatcag tcaaaattta gatttagccc taaagttcaa aaagaataaa aaagataata
    15361 tgaacttaaa gaaagaagta ttaaaaaagg tcggcctaga tttagatatc aagagaattg
    15421 ttagttctct aagcggtggt gaacaacaaa gagtagcatt ggcaagatta atattaaaag
    15481 atccgaaaat cattttagct gatgaaccta ctgggtcact agatacgaaa aatggaaaaa
    15541 tagttattga tttattattg aagctacttg atgaaaataa aactatgatt gtcgtaacgc
    15601 atgatttaga gcttgcgaaa cgatttgatg tcatagtcaa tatttctgag cttagaagtt
    15661 aagaaatatt gataggtata gccatacata gagaaaaaac aatatgaaat atgattagtc
    15721 attacttttg agttttttaa tttaaggact ggattttcca gtcctttttt atgatgacaa
    15781 aaaacaagcc tcgcagagca cacgttttta atgacttatt tggtttttaa taagtctagt
    15841 atgttaaaac ttttctgtgt ttaggtgtta taatcatatg cagtggaagt tgatttatta
    15901 tgtcttattc aattattcga gttgttaaag tgaaatcaaa aacaaataca agaggtattc
    15961 aaagacatat tcaaagagaa aataaaaatt atgaaaatat agatattgat ttaagtaagt
    16021 catatttaaa ctatgattta gtcaatgata ctaagtttga ttttaataaa aaaattgatg
    16081 agaaaatcga aaaaaattat aaagggaaac gcaaaattag aacagatgcc attaaacata
    16141 ttgatggatt aattacatca gataatgtgt tttttaatca attatctgaa gaagagacaa
    16201 aatagttttt taagcatgct aaagcgttct tggaagaaga atacggtaaa gaaaatcttt
    16261 tatatgcgac agtacatatg gatgagataa caccacatat gcattatggc gtagttccta
    16321 ttactaaaga tggacgttta agtgcgaaag aagttgtagg taataaaaaa gcattaaccg
    16381 aattccaaga tagattcaat acgtatatta ataagcaagg ctatgattta aaacgaggaa
    16441 tttctagaca acttacaaaa gaaaaacatg atcaagttag ccgttataaa caaaaaacag
    16501 aatatcataa acaaatgcat atgcgctaga agcaaataga ggattattta aagcaagaaa
    16561 atgataaatt gatacaaaac taccaaaaat cattagatac gcttaaaaag cttctgagtg
    16621 tcatgtatga aattaaaact aaaaatgtag gtggatggtt tcataaagag aagcaagaaa
    16681 caggcaatat tgtaattact aaaactgatt ttgaaaaata cactaaacaa attaaagcag
    16741 cacagatgat attagatgat tatgaatgta ttaaaagtgg gaagtcatta aaaaaagcag
    16801 agaaacaaaa tgaaagttta gttaatgaat tgactagtgt ccatatggaa aatgaaaagc
    16861 tggttgaaga atttaatgat ttagcacaac gttataatta tttgttgtca gagaatgaaa
    16921 agaaagataa agaactaaat tatacgctta agttattcaa tcaagttttt aaaatcatta
    16981 aaagtatgat gaaagaagag cgttatcata cactaataaa tcatattgat aatcatttag
    17041 acaattctaa aatacgtgaa gtaatgacga tagataacaa tgatgaacag ttctttaaga
    17101 agaaatatca agcacaagaa cgagaaatca tttttaaaga agatagagaa gatggttata
    17161 cattataaaa atagatattt aaatgcattt gtttgaggtt aattattttt taggatgaaa
    17221 aataggtagc ccccctcgaa ctttttaata tatttttata aatcttttta aaaacctttt
    17281 taggggcttg ttcagcccta gagcaacaag ggatttcaat gcctaaagga gtgtttttgc
    17341 cacataaaag gagtgttttt gccacataaa aggagtgttt ttgccacata aaaggagtgt
    17401 ttttgccaca taaaaggagt gttttaaaaa gttgtactcc ttttatggtt tgacattgat
    17461 aataaagtag tttattgtga ataaaagttt tcaaatggga gtgtatattc aaacgatact
    17521 cctttaggtt cgtaataaag ggggctgtat catgacagga gagacagttg tatataaaaa
    17581 tgaaatgaat ttagttccat taaggcgatt tacagctact gaaattaatt tattttttgc
    17641 gatgtgtaat aaattaaaag agcaagatac taatacatta cgtttgtctt ttgatgaatt
    17701 aaaaaaatta agtaattata gtccagaaac acgtaatatt aatagatttg ctaatgattt
    17761 agataatgtg tataaaaaga tgttgaattt aaccattaga tatgaagatg atgatgtaat
    17821 agaaagattc gttttattca atcattatag aatccataag cgagaacaat atctagaaat
    17881 atcaacttct tcaaatttaa aacacatatt gaattcaatt actaataatt ttacaaaatt
    17941 tgaattaaaa gaaatgacta ggcttaaatc tacatattct aaaaatatgt ttagattact
    18001 taaacaatac aaacatacag gctatttaaa aattcacatc gatgatttta aaaatcgttt
    18061 agatatacct aaatcttatc gtatgactga tattaacaaa aatgttttta aacctattat
    18121 tattgaatta ggttctatat ttaataatct tactatcaat aaaatcaaag cgaaaaaagg
    18181 gcgtaaaatt gaatggatag agttcacatt tgacgctgag aaacgcattc ataacaaacg
    18241 acaacctcaa atgtccaaga tagataaatc aagacaatat gtgaggcgtg aaaagacgcc
    18301 taaatggtta gaagaacggt catatgaaaa gcaacctcaa aaagattacg acccacaatt
    18361 agagaaagaa cgagaggatt ttttaaaaca acttgaactg aattgggaat aacgcaactt
    18421 ttcgttgcga gttggttaac taaaagtatc gtgacttttc aattatttta attatagttt
    18481 gagttaagga gtgattttat gaaattagct gaagctataa aagaacagag agaattaaaa
    18541 ggatggtctc aagaggaatt agccaatata ttaaaggttt ccagacaaag tgtttctaaa
    18601 tgggaaagtg ccaaaaacta tccttcctta gatattttga ttgctatgag cgatttattc
    18661 ggaatctctt tagagcattt aattaaagga gatgcacgtt ttaaaaaagt tattttagag
    18721 ggaaattata gagagagtaa cagggtacct tccatagttg attttcttta tgatttttgg
    18781 tggcttttct ttcctgttgc cggattttta gtttgggcca ttcattcgtt catgggttga
    18841 ttttaaaatc aaaatttaat gcacatcagg caatatgaaa aaggaaagta tttttacgac
    18901 accttgaaat gtattgataa gaatagaaga gtttacaaaa ggcaatatga aatatatact
    18961 aaaagtaaca agaatttcgt ttgtaaacgc acaaaacccc gaactattcg ccgtagttcg
    19021 gggttttgtg gtgaattggc tttaatcgtc tatattattt tttatcacgt ttatggagct
    19081 aataaccaaa taacgtaacg agacaaccac tgattgccgt tgtcatgatg tgaacaagaa
    19141 tttcattcat aaatcgcacc tcctctctac gccgaattga catctgagag atagacgacc
    19201 ttcacattat aacaaatctc tccttccatg aaataacatg aatattaata aatgttgtta
    19261 tatattaaag ataaataaat ataagggtgg gattgataat gtttggcgat caaagacaag
    19321 aagctacaaa atatgtcatt aaagaaggtt atcaagatat ttatttcctc aacaaaaacg
    19381 gggaatggta ttatttcgaa gtaagaagtg tctggcgtgg caaacatatt attagagtta
    19441 aagatggttt gttaggttgg agaaaagaaa tagtaactga ataaagatac aaaatacttg
    19501 ccaatgcaaa agaatgaaaa cgcgtcaaat caacgatgta taaaagatgc ataaaagata
    19561 atgaaagtaa aaagccataa atgccgtcat ataggcattt atggcttttt gtttggttaa
    19621 cataatcgat gattatcaga agttcaattc acataaaaaa gcacggctaa tttatgaact
    19681 tgtcgtacct ttttaattaa aattagttac caaatagacg actccaaaac ccctttttag
    19741 gttccgtttc ttcactcttt tcttctatat cactatcatt gtcatttgga ttagctgaaa
    19801 cgtcttctct ttgtgcttct tcaccttgtg tactttcgtc gctttgactt ccagatatat
    19861 ccttatattg aatctctgtt tctttagttt cttcctgatc tcggttaata tttacaggac
    19921 tagtagtata tgttttttct tgtgcatcaa cgttttgtct agcgttagta gatgtatcaa
    19981 agggataatt aaggtgtttt tctttttcta attgattttc taatttttga atctttttat
    20041 tactctctaa tgccagaact tgctgattct caagcaattt tgatctttct tgcaactctt
    20101 ttctgtaaaa ttcaattgtt gtttcatgac gactttcttg tttttcaatt tgattattta
    20161 aagtattaat ctgattttta agtatttcta ctatttgagc atcgctttta gattcaaaat
    20221 taatattatc cgactctttt ttttgtttgt cttcagtagc actttcaaaa ccatatttct
    20281 ttttattttc atttactctt tgaatgattt tttctatatc ggtatcttct ttaataaacg
    20341 aagtgttttc ctgttttatt gtctctatat tcaatctctt aatattatta aaaatcgttt
    20401 gcttactaac ccctaattct tcactcaacc tttttacact tttcatatca tcaacccttt
    20461 ataaaatgtt tataaaccct tagtaaaata ttataagctt ataacgatta ataataaagt
    20521 aatcgacaaa taaaaatata aattcgccaa cctttttatc aagggtttgt aaagggttta
    20581 tggtgtttat caaaggttta taaacctata ttttcccttt tttaagttta ttcaaagtgc
    20641 tataataacc ttaatataac aaaaacccca actactggta atagtcgggg t
//
