LOCUS       NZ_CP061279            33310 bp    DNA     circular CON 05-JAN-2024
DEFINITION  Klebsiella pneumoniae strain AH8I plasmid pHNAH8I-mcr1, complete
            sequence.
ACCESSION   NZ_CP061279
VERSION     NZ_CP061279.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN16067814
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 33310)
  AUTHORS   Lv,L., Wan,M., Wang,C., Gao,X., Yang,Q., Partridge,S.R., Wang,Y.,
            Zong,Z., Doi,Y., Shen,J., Jia,P., Song,Q., Zhang,Q., Yang,J.,
            Huang,X., Wang,M. and Liu,J.H.
  TITLE     Emergence of a Plasmid-Encoded Resistance-Nodulation-Division Efflux
            Pump Conferring Resistance to Multiple Drugs, Including Tigecycline,
            in Klebsiella pneumoniae
  JOURNAL   mBio 11 (2), e02930-19 (2020)
   PUBMED   32127452
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33310)
  AUTHORS   Lv,l., Gao,X., Wan,M. and Liu,J.-H.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-SEP-2020) College of Veterinary Medicine; National
            Risk Assessment Laboratory for Antimicrobial Resistant of
            Microorganisms in Animals, Guangdong Provincial Key Laboratory of
            Veterinary Pharmaceutics Development and Safety Evaluation, South
            China Agricultural University, NO. 483, Wushan Road, Tianhe
            District, Guangzhou, Guangdong 510642, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 11-MAY-2018
            Assembly Method                   :: SOAPdenovo v. 2018-05-11
            Assembly Name                     :: pHNAH8I-mcr1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/05/2024 06:16:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 40
            CDSs (total)                      :: 40
            Genes (coding)                    :: 39
            CDSs (with protein)               :: 39
            Genes (RNA)                       :: 0
            tRNAs                             :: 0
            ncRNAs                            :: 0
            Pseudo Genes (total)              :: 1
            CDSs (without protein)            :: 1
            Pseudo Genes (ambiguous residues) :: 0 of 1
            Pseudo Genes (frameshifted)       :: 0 of 1
            Pseudo Genes (incomplete)         :: 1 of 1
            Pseudo Genes (internal stop)      :: 1 of 1
            Pseudo Genes (multiple problems)  :: 1 of 1
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP061279.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..33310
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="AH8I"
                     /host="chicken"
                     /db_xref="taxon:573"
                     /plasmid="pHNAH8I-mcr1"
                     /geo_loc_name="China"
                     /collection_date="2017"
     gene            complement(join(32539..33310,1..458))
                     /gene="taxC"
                     /locus_tag="ICC22_RS00005"
                     /old_locus_tag="ICC22_00005"
     CDS             complement(join(32539..33310,1..458))
                     /gene="taxC"
                     /locus_tag="ICC22_RS00005"
                     /old_locus_tag="ICC22_00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001329504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA relaxase/nickase TaxC"
                     /protein_id="WP_001329504.1"
                     /translation="MGVYVEQEYRIKRAKGTGRDPKSPKLSGRHIHASKSAFNHKVRHG
                     ADKKAYTWTPTKEVTFKITGSGKTAAGIKNGIDYITRNGELEAYCYDGKGSEQTGKGED
                     FNREFTSTLSKGNDYSRTYRGENIDHVKNMVFSPPPEAGVSREDALKATVEFLKETYPN
                     HAFVAVYHDDKEDHPHVHVNIKLRDEETGRRLRLTKSETRKFRNGFHRKLKGMGYDVTA
                     TWKKDPERKREIERLQAENPKRLRNVYKVVDFGETSYQNKAGEKRTPFLTYETLKGGKQ
                     VTIWGKDLKNHFESEKLQPGTLIKVKKLAPTLVRSPMFNDDGTVAGYRETHRNNWQIEN
                     IALERNRERQVHERETRQPEESDVKKQLSRKHEQGHNIGFALEHGFTKDSEEHKKLRIQ
                     QERNWKGLGF"
                     /name="taxC"
     gene            complement(462..965)
                     /gene="taxA"
                     /locus_tag="ICC22_RS00010"
                     /old_locus_tag="ICC22_00010"
     CDS             complement(462..965)
                     /gene="taxA"
                     /locus_tag="ICC22_RS00010"
                     /old_locus_tag="ICC22_00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000781813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome-coupling protein TaxA"
                     /protein_id="WP_000781813.1"
                     /translation="MKMIAFRLSDDELKFAEHNAILSGFTSINAFAKHNVLNIETKPVN
                     IPVNNEPAKLVSVRLYPHEIELVKRNAALHGMSMSREIAIRVRQSLLKSEVCLYPDEVK
                     ELKKLSTAVDRVGRNIHFIIKGERFCTVNDPDFRKDVIEVIELCKQIDSKLETLTKSVV
                     NRFG"
                     /name="taxA"
     gene            complement(1326..1673)
                     /locus_tag="ICC22_RS00015"
                     /old_locus_tag="ICC22_00015"
     CDS             complement(1326..1673)
                     /locus_tag="ICC22_RS00015"
                     /old_locus_tag="ICC22_00015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="WP_000681613.1"
                     /translation="MKHLKYKGYLGTVEPDFENNVLYGKLAFIRDLVTYEASTLAELEQ
                     EFKTSVDLYLQSCVEDGKEPDTPFKGVFNVRLDPELHRRVAEMAMEEDLSLNAFVNKAL
                     EKEVSNHRAGA"
                     /name="type II toxin-antitoxin system HicB family
                     antitoxin"
     gene            complement(1670..1918)
                     /locus_tag="ICC22_RS00020"
                     /old_locus_tag="ICC22_00020"
     CDS             complement(1670..1918)
                     /locus_tag="ICC22_RS00020"
                     /old_locus_tag="ICC22_00020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005653200.1"
                     /GO_function="GO:0003729 - mRNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family toxin"
                     /protein_id="WP_000520549.1"
                     /translation="MGKTDKLLAKFLNSKKTFEWDELVVLFSSLGYVKKEMQGSRVRFF
                     NAEINHTILMHRPHPESYIKGGTLKAIKQNLKEAGLL"
                     /name="type II toxin-antitoxin system HicA family toxin"
     gene            complement(2223..2573)
                     /locus_tag="ICC22_RS00025"
                     /old_locus_tag="ICC22_00025"
     CDS             complement(2223..2573)
                     /locus_tag="ICC22_RS00025"
                     /old_locus_tag="ICC22_00025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000854261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000854259.1"
                     /translation="MKTLKQAAMQFASDLRNNRCFKAAYNDALLELDREDLNAIVQCTF
                     LFEPKRTLAELDKLIKKIEVEEDYEFCVSLDKGKGLHEVRTFKSEREALDAYRILTLYG
                     YTVTIEKKEGND"
                     /name="hypothetical protein"
     gene            complement(2664..2882)
                     /locus_tag="ICC22_RS00030"
                     /old_locus_tag="ICC22_00030"
     CDS             complement(2664..2882)
                     /locus_tag="ICC22_RS00030"
                     /old_locus_tag="ICC22_00030"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_005058042.1"
                     /translation="MHKDTGQQYVVIFTDNNKIRDYKAGIVPQFGELKQSDVDLVLFYR
                     DEYEKYFDSLKDGDECLSFKDFIECLC"
                     /name="hypothetical protein"
     gene            complement(3417..3644)
                     /locus_tag="ICC22_RS00035"
                     /old_locus_tag="ICC22_00035"
     CDS             complement(3417..3644)
                     /locus_tag="ICC22_RS00035"
                     /old_locus_tag="ICC22_00035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000801440.1"
                     /translation="MKPDNTPENVKKLRLKAGLTQKECSHIYGVGLRTWQKKEEVNTQN
                     SQSLSLVEFEFLLLLAGEHPEYVLCKRESK"
                     /name="hypothetical protein"
     gene            complement(3631..3882)
                     /locus_tag="ICC22_RS00040"
                     /old_locus_tag="ICC22_00040"
     CDS             complement(3631..3882)
                     /locus_tag="ICC22_RS00040"
                     /old_locus_tag="ICC22_00040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001565860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001230707.1"
                     /translation="MRKNKGDVTYFLEKEGDNYRLTKRIKARTNVKIGNKTTKITLYDA
                     VLNENELQHIDFTCAGLREDDETPVKNLIKEFMLNETR"
                     /name="hypothetical protein"
     gene            complement(3879..4421)
                     /locus_tag="ICC22_RS00045"
                     /old_locus_tag="ICC22_00045"
     CDS             complement(3879..4421)
                     /locus_tag="ICC22_RS00045"
                     /old_locus_tag="ICC22_00045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001083906.1"
                     /translation="MNSFFEQYHPVFEVVCRILGNGWRVNKLDDCSSRIKLTSPQFKNY
                     SVHIRMEKDRFSVVGSVDSRSWRSPHHVCTLSRKRNPVDIAADIERKILVNASQEVLQA
                     IEYEKHQVEKKDEILILKGMLSQLVQLESWYGALTGFKAENGLNGKVTEQGDSYDLQIR
                     GLSIDQLVKITGYLKQL"
                     /name="hypothetical protein"
     gene            complement(4526..5041)
                     /locus_tag="ICC22_RS00050"
                     /old_locus_tag="ICC22_00050"
     CDS             complement(4526..5041)
                     /locus_tag="ICC22_RS00050"
                     /old_locus_tag="ICC22_00050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025391.1"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="WP_001025395.1"
                     /translation="MNIQEALNVFGLSGELTEKDIKAAYRKAALKYHPDRNPLGAELMK
                     AVNAAFDVLMANIDKINQFQSTDEHARYNYGDDLEKVLNVLSGLSGLVFEVIGNWVWIS
                     GETITHKETLKEIGCKWAAKKKQWFYRPDEHKSYWNREEHTIEEIRAKYGTTGQRRATG
                     WQRVETRA"
                     /name="J domain-containing protein"
     gene            6456..7322
                     /locus_tag="ICC22_RS00055"
                     /old_locus_tag="ICC22_00060"
     CDS             6456..7322
                     /locus_tag="ICC22_RS00055"
                     /old_locus_tag="ICC22_00060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001473366.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_001353743.1"
                     /translation="MTTNKTSLSRLTKVRHRNELNSTLSTLPMAAKKVLFLAMCQINSK
                     NEFDDDHIFYVTVADYIKWVQVKPDAAYLALRDGSNILDTTLLKLKHDEILELSSDLGF
                     KFTKSNVPDSMNLSLTVFSTYYRNEGRVGIKFTKEAKRFLCKLIGEEKRYTTQVLLSVV
                     RLTSVNAASLYQLIRKIYSNNSRANSFEMTIDELKDELNLYTIGAGGVKDYKYPDYPAF
                     KRDVLNKSVKEIMKHTEVKNLSFVVSEKIGRKVYKLKFSYTIGYEGDTREDSEFTNMFD
                     KMYPPEN"
                     /name="replication initiation protein"
     gene            7335..7739
                     /locus_tag="ICC22_RS00060"
                     /old_locus_tag="ICC22_00065"
     CDS             7335..7739
                     /locus_tag="ICC22_RS00060"
                     /old_locus_tag="ICC22_00065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012421203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_012421203.1"
                     /translation="MKDNIVDFQRIRDSMNDHSTDVANDAVYSDKKKISRFFYLLTPVR
                     YLLAASLYLVVVIPLGILAGFRFLLQFLGGIAVMGLTIAWYMGADVSSYVVLAAWIALT
                     VCGCAEQIFEWWIESRFAFRLFGIGRTPEE"
                     /name="hypothetical protein"
     gene            7875..8402
                     /locus_tag="ICC22_RS00065"
                     /old_locus_tag="ICC22_00070"
     CDS             7875..8402
                     /locus_tag="ICC22_RS00065"
                     /old_locus_tag="ICC22_00070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001473365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2726 domain-containing protein"
                     /protein_id="WP_000577043.1"
                     /translation="MIFNRNKKRDEQHNSAVVLPSAENVFSDFIKNNPALTTNAFTAIG
                     EVDCFTKVPLLSNNESEFLGILSRNIIPDYSVFPKIRLIEFVRPHGSEEAVKDLIREVQ
                     NITCDFVLKSYDETVLAVIQFGETATVRQQKKKLIIQRVCAMTGISFFEFKNTVDMMGS
                     EDFCQFLRDDEE"
                     /name="DUF2726 domain-containing protein"
     gene            complement(8793..9539)
                     /locus_tag="ICC22_RS00070"
                     /old_locus_tag="ICC22_00075"
     CDS             complement(8793..9539)
                     /locus_tag="ICC22_RS00070"
                     /old_locus_tag="ICC22_00075"
                     /inference="COORDINATES: protein motif:HMM:NF028536.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAP2 family protein"
                     /protein_id="WP_104772353.1"
                     /translation="MGGGVGFVMPYLSNKRLLAEMSIALVMAIVATLTLEHSQINLMVA
                     DWFYLGMGHWMVAKQAFLPDLLLYSGLKKLLMAMLIYLLVATICRAYHEKKGNAITAKW
                     LVPVTKFRVRELAYLVLTLILVPTVVASLKAYTHVVCPVHLTIFDGTLPYLPMLDSMRN
                     TIPDKCFPAAHASSGFALFAFAFAPSLRRRRGAIIIVVMALGWAMGCYKMIIGDHFLSH
                     TVVSMMLAWAMSAGLAWVFFKKGEQV"
                     /name="PAP2 family protein"
     gene            complement(9587..11212)
                     /locus_tag="ICC22_RS00075"
                     /old_locus_tag="ICC22_00080"
     CDS             complement(9587..11212)
                     /locus_tag="ICC22_RS00075"
                     /old_locus_tag="ICC22_00080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_049589868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine--lipid A transferase MCR-1.1"
                     /protein_id="WP_049589868.1"
                     /translation="MMQHTSVWYRRSVSPFVLVASVAVFLTATANLTFFDKISQTYPIA
                     DNLGFVLTIAVVLFGAMLLITTLLSSYRYVLKPVLILLLIMGAVTSYFTDTYGTVYDTT
                     MLQNALQTDQAETKDLLNAAFIMRIIGLGVLPSLLVAFVKVDYPTWGKGLMRRLGLIVA
                     SLALILLPVVAFSSHYASFFRVHKPLRSYVNPIMPIYSVGKLASIEYKKASAPKDTIYH
                     AKDAVQATKPDMRKPRLVVFVVGETARADHVSFNGYERDTFPQLAKIDGVTNFSNVTSC
                     GTSTAYSVPCMFSYLGADEYDVDTAKYQENVLDTLDRLGVSILWRDNNSDSKGVMDKLP
                     KAQFADYKSATNNAICNTNPYNECRDVGMLVGLDDFVAANNGKDMLIMLHQMGNHGPAY
                     FKRYDEKFAKFTPVCEGNELAKCEHQSLINAYDNALLATDDFIAQSIQWLQTHSNAYDV
                     SMLYVSDHGESLGENGVYLHGMPNAFAPKEQRSVPAFFWTDKQTGITPMATDTVLTHDA
                     ITPTLLKLFDVTADKVKDRTAFIR"
                     /name="phosphoethanolamine--lipid A transferase MCR-1.1"
     gene            complement(11386..12015)
                     /locus_tag="ICC22_RS00080"
                     /old_locus_tag="ICC22_00085"
     CDS             complement(11386..12015)
                     /locus_tag="ICC22_RS00080"
                     /old_locus_tag="ICC22_00085"
                     /inference="COORDINATES: protein motif:HMM:NF022440.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2806 domain-containing protein"
                     /protein_id="WP_223424520.1"
                     /translation="MSLIDLSLSGLSEPGTKLIEKISDAIGVLYEPTRIRKKAKAEAEA
                     KRTELISRLELEGIEKRAVERFLKRETKRQENIENITMQAAQSLSESDNVSDIDEDWIE
                     AFFRECEDISDEQMQMLWGRILSEEAKSKGSFSRRTLKLLSTISKEEANLITYFGKFVW
                     QANKLTPILFTDENGDTEGITFDKLSVLDSLGVIQQGIGYSLRYKL"
                     /name="DUF2806 domain-containing protein"
     gene            complement(12176..12445)
                     /locus_tag="ICC22_RS00085"
                     /old_locus_tag="ICC22_00090"
     CDS             complement(12176..12445)
                     /locus_tag="ICC22_RS00085"
                     /old_locus_tag="ICC22_00090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001086090.1"
                     /translation="MAKLELPELEQNQEVNATKFVQDAGKRPTENKTKLASFRIPNELL
                     EFIDNESKRLHRPKTKIIKAALLAYQDLDENELINLWFRADRND"
                     /name="hypothetical protein"
     gene            complement(12520..13167)
                     /locus_tag="ICC22_RS00090"
                     /old_locus_tag="ICC22_00095"
     CDS             complement(12520..13167)
                     /locus_tag="ICC22_RS00090"
                     /old_locus_tag="ICC22_00095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001694199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division plane positioning ATPase MipZ"
                     /protein_id="WP_000587671.1"
                     /translation="MIIVIGGDKGGTGKSHLATNLTVCLSQQGKRTGLVETDLNGSTKK
                     WNKRREQAGLPPVALNEAYGDISAKITKMADVAEILIIDTAGYDSTEFRTALKVADIVI
                     VPIDPLAQVEADSLQTVTKIVRDAQKINPRLAAHVLLYKCQPNTFSEQQELRDSLNSHD
                     YWLKPMKSTVSFLRAFVRAMNQGMGVHELKSNVSGASQAKAQIELLLKELEL"
                     /name="division plane positioning ATPase MipZ"
     gene            complement(13830..13925)
                     /gene="dqlB"
                     /locus_tag="ICC22_RS00200"
     CDS             complement(13830..13925)
                     /gene="dqlB"
                     /locus_tag="ICC22_RS00200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinQ-like type I toxin DqlB"
                     /protein_id="WP_021534057.1"
                     /translation="MINMLIIVLRAVVAVANALIAVLELIRQFID"
                     /name="dqlB"
     gene            complement(14708..15412)
                     /locus_tag="ICC22_RS00095"
                     /old_locus_tag="ICC22_00100"
     CDS             complement(14708..15412)
                     /locus_tag="ICC22_RS00095"
                     /old_locus_tag="ICC22_00100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(15499..15963)
                     /locus_tag="ICC22_RS00100"
                     /old_locus_tag="ICC22_00105"
     CDS             complement(15499..15963)
                     /locus_tag="ICC22_RS00100"
                     /old_locus_tag="ICC22_00105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293133.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0030527 - structural constituent of chromatin [Evidence
                     IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS family nucleoid-associated regulatory
                     protein"
                     /protein_id="WP_001293134.1"
                     /translation="MSELTKEDEYGIISRTMMNIRSLRVFAREIDFEQLLEMQEKLNVV
                     IEERREDAEREAAERQELEAKRQQAIEYIISLGLDPESLLAPVTADTVKTRRKAKGGVR
                     KAKYRFKDENGEIREWSGNGKRPLALQKLLDEGHFMEDFLIEKTKPEQAE"
                     /name="H-NS family nucleoid-associated regulatory protein"
     gene            complement(15981..16187)
                     /gene="hha"
                     /locus_tag="ICC22_RS00105"
                     /old_locus_tag="ICC22_00110"
     CDS             complement(15981..16187)
                     /gene="hha"
                     /locus_tag="ICC22_RS00105"
                     /old_locus_tag="ICC22_00110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="WP_000850859.1"
                     /translation="MKTKQEWLFQLRKCTSRDTLEKVIEINRYKLPLSESEAFYSAADH
                     RRAELVMNKLYDKVPSGVWKYVH"
                     /name="hha"
     gene            complement(16184..18337)
                     /locus_tag="ICC22_RS00110"
                     /old_locus_tag="ICC22_00115"
     CDS             complement(16184..18337)
                     /locus_tag="ICC22_RS00110"
                     /old_locus_tag="ICC22_00115"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247728.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="WP_001235745.1"
                     /translation="MRLFIAEKPAVANDIVKALGGNFTRHDGWFESDNAIVTNCFGHII
                     ESQPPENYNPEYKAWKVETLPLRLYPVKYQPVESAAKQVKTILELIRRGDVTEIVHAGD
                     PDDEGQLLVDEVLEYAGNTKPVKRVLINDNTLPAVKKALANLKDNRDFKGLYLKALARS
                     VADAVYGFSMTRAYTIPAKARGYQGVLSVGRVQTPVLGLIVNRTRANQNHKSSFYYTMT
                     GVFQRGADVIRANWKPGEFAPLTDRKLLDKAWADGTAASLAGKPATVEAAATDDKKTAA
                     PLPFNLVRLQQYMNKKFKMTAQKTLDITQQLREKYKAITYNRSDCSYLSDEQFSEAPQV
                     IDALKSVFPQSLDIDSARKSKAFNSAKVTAHTAIIPTASVPDVNALSTDERNVYLAIAQ
                     HYLVQFMPEKAYQEVSVAIQCGDESFYARARKTTDSGFEAFLGAETTDEGESEDNDDSA
                     FELLCKIRTGETLTTKEVIVNEKKTTPPPLFTEASLLAALVRVADFVTDPTIKKLLKDK
                     DKDKKDEHGGIGTPATRAAILETLKKRNYITLEKGKLIPTDTGYALIDALPGIAVNPDM
                     TALWSEKQAAIENGDLTVEQFINDLYGELTGMISDVDLGEMKIEPAAPAGQFQRLDSPC
                     PSCGKHIVIRPKGYFCTGCEFKIWSEFSGKKITQAQAEKLVKSGKTDLIKGFKKKSGGT
                     YDTVLVLEDKKTGKLGFPARAKK"
                     /name="type IA DNA topoisomerase"
     gene            complement(18342..18914)
                     /locus_tag="ICC22_RS00115"
                     /old_locus_tag="ICC22_00120"
     CDS             complement(18342..18914)
                     /locus_tag="ICC22_RS00115"
                     /old_locus_tag="ICC22_00120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001198960.1"
                     /translation="MQYALFDGFERKFLLDALEFGVLKDWKENPVKELPDIDESAHPFH
                     ICYGGYLLNPGVSDSDISRKIKDQAGFWLAAIDDTRMDCHSIAYYDIHTLPLISCGHQK
                     IVPFAALIKADECIISKIASYSGFAVTAFLRIKEWDIATNILNREGIFAFNGCERRFRV
                     VSKDNWQHTVSEERAIRCAKRLIQCKG"
                     /name="hypothetical protein"
     gene            complement(18918..>19112)
                     /locus_tag="ICC22_RS00120"
                     /old_locus_tag="ICC22_00125"
                     /pseudo=""
     CDS             complement(18918..>19112)
                     /locus_tag="ICC22_RS00120"
                     /old_locus_tag="ICC22_00125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517490.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /name="ATP-binding protein"
     gene            complement(19225..19530)
                     /locus_tag="ICC22_RS00125"
                     /old_locus_tag="ICC22_00130"
     CDS             complement(19225..19530)
                     /locus_tag="ICC22_RS00125"
                     /old_locus_tag="ICC22_00130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001350475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_001350475.1"
                     /translation="MTGKNRVVLPALLALGLISTNANASDPCASVLCLYGKAVGQGGGS
                     ECRSAEKDFFNILKKKKGSIRWSKTFDARKAFLNQCSTADPAAISKIMSKFGRVRG"
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            complement(19514..19936)
                     /locus_tag="ICC22_RS00130"
                     /old_locus_tag="ICC22_00135"
     CDS             complement(19514..19936)
                     /locus_tag="ICC22_RS00130"
                     /old_locus_tag="ICC22_00135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001353737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="WP_015059903.1"
                     /translation="MMKKLVFLLISILAGCSSPPEPTPVQFEKANEVINPSLPYVPDFH
                     GVIKSDVSGKGWVYEITSLSGVQARTPTFYYALAHADRIVVTTHDAGLWFRIRDLLKME
                     GATAVVEWRNEKSFLPEQVKIVFIKAQNEVKNDWKK"
                     /name="cag pathogenicity island Cag12 family protein"
     gene            complement(19945..21807)
                     /gene="taxB"
                     /locus_tag="ICC22_RS00135"
                     /old_locus_tag="ICC22_00140"
     CDS             complement(19945..21807)
                     /gene="taxB"
                     /locus_tag="ICC22_RS00135"
                     /old_locus_tag="ICC22_00140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome-coupling protein TaxB"
                     /protein_id="WP_170324155.1"
                     /translation="MKTFNKSQSVFIFAVMLVAAWFAGSFIFFVLYFSQIKNLKPLKAV
                     FRSIDAYRMDIFTDSLTLSVVTTDIRVLAFVALGAGFVVSLIIPVAALIKLNEKKENIF
                     GDARFATINDIRESNSFTLDGDEKDGIIVGIKDKKIIRYVGAAFSAMGAGTRAGKGAGI
                     VITNLMKYWWSVIILDPKRECFNITSLIRKVILGHEVYKFDPFSSVTHRFNPLYYVSMG
                     TSEGFNQLENLSLIIYPYKTDGADAGSYLNKTAGGVFKSYAVALWFMIKNDKAGLKTLD
                     IEPVFSMSKINQLFERAEPEHLLSFMNDIRSELRGKDKTLADIGVAGLKAFIEMEDKTK
                     AQLKSNFLNGLSPFANPNVANATDGNDFDLRQVRKKRMTIYFCISGDNARLAEKITNIF
                     FQLAIQVNLEKMPTDDPEIKHDCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQV
                     GSQLEEIYSYAGSKTLLASAPCKIVYSASDVKDARELSEAMGTRTVTIGSKSKSRSRGG
                     TSRSESESLIERPLVTTNELLTLKFSEEILAMKGENPIRCEKAFYYLNEYFFGDFVKVA
                     PELANIFPRKKGKLVMPPQKVFENEIVAKGYLVVKDVPDLDKAA"
                     /name="taxB"
     gene            complement(21794..22822)
                     /gene="virB11"
                     /locus_tag="ICC22_RS00140"
                     /old_locus_tag="ICC22_00145"
     CDS             complement(21794..22822)
                     /gene="virB11"
                     /locus_tag="ICC22_RS00140"
                     /old_locus_tag="ICC22_00145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401678.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_000017226.1"
                     /translation="MSGVIPVSISNKSLDFYKNQVFQSFLDIEGLTEIAVNRPGEIWTE
                     INGDWTFHNNDSVTFDFCKRFSHTLASFRGDEIGETKPLLSATLESGERVQVVFPPACE
                     RNTISITIRKPSTRQITHKEYVANGFYDYVQSGKKHRTYDDELLDLFRARNIAAFMELA
                     VAAGKTIVFAGATGSGKTTYMKSLIDFIPLNTRLITIEDAEEIKFFIHKNYVHLFYPSE
                     SGSDSGSIITAAKLIKSCLRMKPDRILLAEIKGGDAWDFVKVAGSGHSGSMTSIHAASA
                     KDAIIQMVTKCYQNRECQNLPFDVLRKIIMDSIDIVVHVGRDGVVRHMSDIYYKGAECE
                     NF"
                     /name="virB11"
     gene            complement(22824..23942)
                     /gene="virB10"
                     /locus_tag="ICC22_RS00145"
                     /old_locus_tag="ICC22_00150"
     CDS             complement(22824..23942)
                     /gene="virB10"
                     /locus_tag="ICC22_RS00145"
                     /old_locus_tag="ICC22_00150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB10/TraB/TrbI family type IV secretion system
                     protein"
                     /protein_id="WP_000131271.1"
                     /translation="MTDMKKTDDLVDDANQSKLESKPVHDIGDIRNKNNRMRSGFLFGL
                     MAVLVIGIFALKTYKNYFADDQQKASESTGDTSISQVSKIRTGLGQNFDPVENKAIINP
                     GATGSGNTVSDGHKEVPQEGFRKYLSIPVAGQGGSQTGASGSSRTSQTSEPQEERKESK
                     ENVPGKSGMKVTAINLDPDLYIEENRLIPCALTTRFVSDVAGRISCVFTEDVWSANHHT
                     KLLEQGTKAFGRYQTGTLNHGQGRMFVMWEQLRTPDNKRIDMVNTAAAGPLGEAGIDGW
                     IDSHFWERFGGSLMLSMVQDVAAAAADNAPGKDRNVDYTENSRQAMAEMAKVALENSIN
                     IPPTMYKNQGDIITIMVGEDIDFSDIYELKVK"
                     /name="virB10"
     gene            complement(23935..24843)
                     /gene="virB9"
                     /locus_tag="ICC22_RS00150"
                     /old_locus_tag="ICC22_00155"
     CDS             complement(23935..24843)
                     /gene="virB9"
                     /locus_tag="ICC22_RS00150"
                     /old_locus_tag="ICC22_00155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001299943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein VirB9"
                     /protein_id="WP_001329500.1"
                     /translation="MMKKLFIATCLLLPGLVYSAATPLPSGFDARMQTVSYNGANTTVI
                     RSKTGFLTSVVFDEGEAVISAKAGFPAGWEITTDDNVVYINPRPVVQEQEGDEGEKLKK
                     VFQPTEKEWDTNLFVRTTKRIYSLDLILLSEEKQAQPAYVVQFRYPSEIAKKNAEEVRL
                     AKEKQEKLRQKKLISESFEKADAPKNWNYFMRVNEKYDSRRIAPDFAYDNGIFTFLGFN
                     SGKVFPAPFAVRDGQEQTLAFNVETKGKYKIMVIHNVNDKFVLRYGNSVVGVVNKSFGK
                     VLTDQRNTSSPAVERVEVNND"
                     /name="virB9"
     gene            complement(24840..25526)
                     /locus_tag="ICC22_RS00155"
                     /old_locus_tag="ICC22_00160"
     CDS             complement(24840..25526)
                     /locus_tag="ICC22_RS00155"
                     /old_locus_tag="ICC22_00160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_001290765.1"
                     /translation="MSEKIEKKIETAKSFERQLYAENERSKKNAWRVAVAASLLSLCLG
                     AAICVLVPLKEKELAIVAVGEKTGRTELITQVKQEKILQSEALGRYFVNTYITLREGYN
                     YPSLQYDYETVQLYSSNTVKDDYLRLYNSDMAPDKIYHNNGSYVAVEVISNIISDATAP
                     DKLASVRFKKTTRNFTTGQVSVSYWTARVTYRFEPEKSVKSSSRELNPLGFTVTSYQTD
                     REVRGE"
                     /name="type IV secretion system protein"
     gene            complement(25865..26014)
                     /locus_tag="ICC22_RS00160"
                     /old_locus_tag="ICC22_00165"
     CDS             complement(25865..26014)
                     /locus_tag="ICC22_RS00160"
                     /old_locus_tag="ICC22_00165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012421205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_227648764.1"
                     /translation="MSLNWILVFVDKHITSGWSRKRKLITQLVILITGITLFKVLGGIS
                     QSWL"
                     /name="hypothetical protein"
     gene            complement(26041..27135)
                     /locus_tag="ICC22_RS00165"
                     /old_locus_tag="ICC22_00170"
     CDS             complement(26041..27135)
                     /locus_tag="ICC22_RS00165"
                     /old_locus_tag="ICC22_00170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001677777.1"
                     /GO_process="GO:0030255 - protein secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000046889.1"
                     /translation="MAQGFFVKYNSTVMDSVDKISSSYQTQFANDIMSLATVSVTLYVL
                     WKGYQILASKTQTPLQDLVWDLSKFAIIIMFITNADGYLTAATDALQGMKDGFSGGVSV
                     WQTLDNLWKSTQNLGAEIYSLDKSTYVKDQGVVGQFLIWTGSLILMAVSVVVFLTADVT
                     MKLLIITAPIFIFCLMFGFIRSMFNNWLQSLFSSILTVLFASLVIRIAMDFQGMILSHA
                     IRAAQTGNVNLVSTGAMGFMAGFLGALLVLIAKGFAVQLAGAGVEGAVQGAAMMGLGAA
                     GMATGKSLMLGGRAGLGFGLGMAGRTGMNSLSGKAGNLMGRGARTAAEWAGEKGYQALA
                     PTGALGMKARRLASLEKARARNAA"
                     /name="type IV secretion system protein"
     gene            complement(27147..27863)
                     /locus_tag="ICC22_RS00170"
                     /old_locus_tag="ICC22_00175"
     CDS             complement(27147..27863)
                     /locus_tag="ICC22_RS00170"
                     /old_locus_tag="ICC22_00175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000832283.1"
                     /translation="MKRVKTLMLISLLTASFYSSAGIPVAIDASPEWAVEAARWTERLK
                     QWSETAQHYQSQIQAYKDQLATATGIRNIAAFTNELSNLQSELTNIYKQGNSYISDFTS
                     NPEGALSSQAKNLFSKYGAFDMCNTGYERNDNLCKARIVSTAASIEQGNEINKQLSSAM
                     SQIQSLSSRIEASKDIKESQDLANALQAQSLKMQAIKMQYDVWNNKNKADHEMLVTQEQ
                     EAFIKQQKEAEPLTFD"
                     /name="type IV secretion system protein"
     gene            complement(27875..30622)
                     /locus_tag="ICC22_RS00175"
                     /old_locus_tag="ICC22_00180"
     CDS             complement(27875..30622)
                     /locus_tag="ICC22_RS00175"
                     /old_locus_tag="ICC22_00180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
                     /protein_id="WP_000105985.1"
                     /translation="MSTLYKAMTRPAMYVGVPVVPLTVVAGALFLAGVYISKLIWLAIP
                     VAVFVLRMITKQDDHIFNLYFLKLKMLGNSVCNRFFGARAFLSGQYEAVEIDEFVNAMK
                     LNERITTGKYIPYSSHVDKNIVKTKNGDYVATWQLMGINFESISAEMLETIDSQVATLV
                     RSFSGLPVSFYNHSCRASFYDAFTTKSGNKYADIISDCYYGSMKKNKFKGNTLYFTLIY
                     RPDGRVEKLEKRKKSIKEKKDDINIHVKRMNEMINTFSGALDKFTCKLLGMYEENGKVF
                     SSQLSFYNYLLTGKLQKIRVTDSPVYNVLGGVDVFFNHDTGQICRIDGNKFFRSIEIKD
                     FCSETASGVFDVLQYSDADYIITHSYTSMSKSEALSTIKRAEKQLKSTEDDAVTQLQEL
                     EKAKNDIVSGDISFGYYHFTLMVMADSIRELDESVSKITADFTDLGIIPALSTMSLPAA
                     YFAQLPAVFHLRPRLSPVSNVNFVELASFHNFYQGKRDKNCWTEAVAILKTPSKQAYYL
                     NLHNSVLFKDETGEKNLANTKVIGTAGSGKTMFLSYLACSLQKYNNPETFADSAKNKKL
                     TCVFLDKDRGAELCIRMLGGEYYTVKSGEPTGWNPFALEATKRNRIFVKQLMEILCTRN
                     GERLSTRERLLISESVDAVMDFPPGEMREYGITRMLEHLMQRDDRDEQENGIILRLSQW
                     ANGQAHGWVFDNAKDTFNIQHVNNFGIDGTEFLDDPMVCAPITFYLLYRITQLLDGRRL
                     VIFLDEFWKWLQDEAFSDFVYNKLKTIRKLNGLVIPATQSPDEILKNKISRAVVEVCST
                     SIYLANPDADYNDYVEGLKLTPEEFNIVKNLDPMSRQFLIKKSSLKKGDGKSFSALATL
                     DLSGLGGYLKILSASADNLEIFESIYHEGMEPDDWVPEYLERAI"
                     /name="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
     gene            complement(30641..30967)
                     /locus_tag="ICC22_RS00180"
                     /old_locus_tag="ICC22_00185"
     CDS             complement(30641..30967)
                     /locus_tag="ICC22_RS00180"
                     /old_locus_tag="ICC22_00185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_000008647.1"
                     /translation="MSFKKSVCNRISSSVTAVMQRKNKVVMAVAGATVASPAFADGFSK
                     AETLLEKVKTGLSGLSLVTVTIACLWVGYKVLFGGSTIRECSPIIIGAIVIASAAEVAS
                     MMVN"
                     /name="TrbC/VirB2 family protein"
     gene            complement(30981..31601)
                     /locus_tag="ICC22_RS00185"
                     /old_locus_tag="ICC22_00190"
     CDS             complement(30981..31601)
                     /locus_tag="ICC22_RS00185"
                     /old_locus_tag="ICC22_00190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_000157549.1"
                     /translation="MASLFPALLLCAASVHPDTINDIARVESGFNPYAVAEIIPERERG
                     SYGKSVISHMPKSKEEALTVIREIENRKRRYSVGLMQITSSNFSFYSTSAEKLLDSCEN
                     LSVFEKIIVDCYKRGRSLENALSCYYTGNFSNGKRKEKEFNNTSYVERIGYTGNEKKYV
                     VPGTRSNGGEQRKNRSHNASVIWPETILKSAFVDNSHPTKVIN"
                     /name="lytic transglycosylase domain-containing protein"
     gene            complement(31957..32172)
                     /locus_tag="ICC22_RS00190"
                     /old_locus_tag="ICC22_00195"
     CDS             complement(31957..32172)
                     /locus_tag="ICC22_RS00190"
                     /old_locus_tag="ICC22_00195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="WP_000760375.1"
                     /translation="MKKYLLFALPFFVVGCSEEVKSVDWWGQHLTEAKQKQAECEKSGS
                     DSQNCKNVKQALFIQSQKDAPVPTFD"
                     /name="EexN family lipoprotein"
     gene            complement(32169..32462)
                     /locus_tag="ICC22_RS00195"
                     /old_locus_tag="ICC22_00200"
     CDS             complement(32169..32462)
                     /locus_tag="ICC22_RS00195"
                     /old_locus_tag="ICC22_00200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134733.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]; GO:0016987 - sigma factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="WP_060598542.1"
                     /translation="MTEHDAICISGLHQIFSDEEHLSEQQKDIILMYAYGYTLNEIADF
                     KGLKPSTVRKYLDSVRAELGGVSLAGIRTLVLIRTNALLVSSLSRISERGNL"
                     /name="sigma factor-like helix-turn-helix DNA-binding
                     protein"
     ARG             complement(9591..11212)
                     /name="mcr-1.1"
                     /gene="mcr-1.1"
                     /gene_name="phosphoethanolamine--lipid A transferase
                     MCR-1.1"
                     /tool="amrfinderplus"
                     /drug_class="COLISTIN"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          6451..7322
                     /name="IncX4"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(4..458)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="99.0"
                     /evalue="1.0499999999999999e-94"
     Typing          complement(32543..33309)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.609"
                     /coverage="99.0"
                     /evalue="8.469999999999999e-168"
     Typing          complement(19949..21807)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="98.71"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(23939..24843)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.669"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(24844..25526)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.4399999999999998e-137"
     Typing          complement(26069..27135)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.719"
                     /coverage="99.0"
                     /evalue="2.69e-172"
ORIGIN
        1 gtagctttca gagcgtcttc cctgcttact ccagcttctg gtggtggtga aaagaccatg
       61 tttttcacat gatcgatgtt ttctccacga tatgtcctgg agtaatcatt tcctttagat
      121 aaagttgaag taaactccct attaaagtct tctcctttcc ctgtttgctc tgaacctttt
      181 ccatcataac agtaagcctc aagttcacca ttacgggtaa tgtaatcaat accatttttg
      241 atgcctgcgg ctgttttacc tgagccagtg attttaaaag tgacttcttt tgtaggtgtc
      301 caggtatatg ctttcttgtc cgcaccatgt ctgactttat gattaaaagc cgatttactg
      361 gcatgtatat gtcttcccga taacttagga gatttcggat cacgcccagt ccctttagcg
      421 cgtttaatac ggtattcctg ttctacatac acacccataa atcacccaaa tctgttaaca
      481 acactcttgg ttaacgtttc aagttttgaa tcaatttgct tacacagttc aatcacttca
      541 ataacgtctt ttctgaaatc tggatcgtta accgtacaga atctttcacc ttttatgata
      601 aaatgaatgt tgcgaccaac acgatctaca gcagttgata gttttttaag ttccttaact
      661 tcatcagggt aaagacagac ttcactcttt aacaaagact gacgcacacg aatagcaatt
      721 tctctgctca tgctcatgcc gtgaagagca gcattacgtt taacaagttc tatttcatga
      781 gggtaaagac gcactgatac cagctttgct ggttcattat taactgggat gttaacaggc
      841 ttggtttcaa tattaagcac gttatgctta gcaaaagcat tgatactggt aaatccactt
      901 aaaatagcgt tatgttctgc aaattttaac tcatcatcac ttagcctgaa cgctatcatc
      961 ttcataagtc accccaacag agcctgcggc aggcacaggc aaaaacatcg tttttggaca
     1021 atctgattca aatgttaaca tttgacatcg gattgtctat cctgcattga ttgtaccata
     1081 tgtggcactg tgcctggcta taaaatcgtc gctgcatatg tccagatttc gttgctgaaa
     1141 gattctttcg tcttcgacca tcaggcaaac gtatagctga aagatttgtg aaagaaaaaa
     1201 caggcctggc agggctggga attgttacgg ctgaagccgt aacgcttttt aagtcctcgc
     1261 tgcgctgcgg ggcttccggc gcaaagcgcc tcccatgccc ttacagggca taaaaacaag
     1321 ggcaattaag cccctgcgcg atgattgctg acttcttttt ccagagcctt attaacaaag
     1381 gcattcaacg ataaatcttc ttccatcgcc atttctgcta cccgacgatg cagttctgga
     1441 tcaagcctga cgttaaacac gcctttaaac ggggtatcag gttcctttcc atcctccaca
     1501 caagactgta aatacagatc aacagatgtt ttaaactcct gttccagttc agctaatgta
     1561 gaagcctcat aagttaccag gtcccgaata aacgccagtt ttccatacag gacattattt
     1621 tcaaaatcgg gttcaaccgt gcctaaatat cctttatatt ttaaatgttt cataataatc
     1681 cagcctcttt cagattctgt ttaattgctt tcagcgtacc acctttgata taactttccg
     1741 gatgtggacg atgcattaat atggtgtgat tgatttcagc attgaaaaac cgcactcttg
     1801 acccctgcat ttcctttttg acatatccca aagaggaaaa caaaacgacc agttcatccc
     1861 attcaaacgt ttttttactg tttaaaaact ttgccagtag cttatctgtt ttccccataa
     1921 atccatcccc tatagatatg caactaatta tagttacaca tggcattttt gtcaaaaaat
     1981 acaaaggggc agaaagcccc tttttttatt taaaacattt catacccttg caagtagttt
     2041 aaccaccacc ggaattgatc ccattcgcta aatttcattg ccggaattct ggtttcccag
     2101 cctttgacaa gggaatcagc aagctgtacg atctgccgcg ttgacattta aaaacctcat
     2161 tcagttttga ttgtcgataa cgtgatcagg ttggtggaac aacctgatca caccttgaat
     2221 agtcagtcat taccctcctt cttttctata gttactgtgt atccgtaaag agtcaaaatg
     2281 cgataagcat ccaacgcctc acgctcactt ttaaatgttc tgacttcgtg taatccttta
     2341 cctttatcaa gggatacaca aaactcataa tcttcttcta cttctatctt tttaattaat
     2401 ttatcaagtt cggctaatgt tcgttttggc tcaaaaagaa atgtgcattg tacaatggcg
     2461 tttaaatctt cccgatcaag ctctaacaga gcatcattat aagcagcttt aaaacagcga
     2521 ttattacgca gatcagatgc aaactgcatt gcggcttgtt ttaacgtttt catgaatttc
     2581 ccttgcattg atgttaatag acaatttcag aatcaatatt gaaatttcca gaaaatgcag
     2641 ggatgcccct gcattcataa tgcttaacaa agacactcaa taaaatcttt aaaactcaag
     2701 cattcatcgc catcttttaa tgaatcaaaa tatttttcat attcgtccct gtagaaaagg
     2761 actaaatcaa catcactctg cttaagttcg ccaaactgag gaacaattcc ggctttatag
     2821 tcacgaattt tattgttatc agtaaatatg acaacatact gttgtccagt atccttatgc
     2881 ataaggataa tagtgcaaag cgttactcgt tcgaatgtga aaacatgatt agtggttgaa
     2941 gtaaaaacag atgagcattt cattttaaat ctcctgccct gctgggctat tgtgagaggg
     3001 gccattcccc tttcgatgaa acaataatac gacctttaag tcgtatttgc aagttttctc
     3061 ccgttttttt actcgataag tgattgttat cacgtttttt aatccgcgta agcggatgga
     3121 aggggcgaac gaaaatacca gggcagcaca ggagccacat cgccccgaag cgcggcgcag
     3181 ccgctgacga acgtaccagg gtgcacaggc catcccttca ccctgcaaag cccaactgac
     3241 cagcaggcca tgattatgct gatttgcgcc gcagaatgcc gcagttagcg cgagcgcaag
     3301 cgagtttacc ccgccctggt gcattgcagc atggcggggc gctgtactgc gcgtgtgagc
     3361 gtcagcgagc tacgagcgca actccaggta ctaatataaa accatcacag gtcattttat
     3421 tttgactccc ttttgcagag cacgtattca ggatgttctc ctgcaagtaa caaaagaaac
     3481 tcaaactcaa ccagtgacag actttgactg ttttgagtat taacttcctc ttttttctgc
     3541 caggttctta gcccaacacc ataaatatga ctgcattcct tttgtgttaa tcctgctttt
     3601 aaacgtaatt tttttacatt ttcaggtgta ttatcgggtt tcatttaaca taaactcctt
     3661 aattaaattc ttaactggcg tctcatcgtc ttcccttaat ccggcacacg taaaatcaat
     3721 atgttgtaat tcattctcat tcagtacagc atcatacaat gtaattttcg tagttttgtt
     3781 cccgatttta acatttgttc tggcttttat cctttttgta agcctgtaat tgtcaccttc
     3841 tttttcaaga aaataagtca catcaccttt attttttctc ataactgttt caaataccct
     3901 gtaattttaa caagttgatc tatactcaag ccccgaatct gtaaatcata actgtcgccc
     3961 tgttcggtga ctttaccgtt caatccgttt tcagctttaa agcctgtcaa tgccccatac
     4021 cagctttcaa gctggacaag ttgcgataac atacctttca ggatcagaat ttcgtccttt
     4081 ttttccacct ggtgtttctc atactcaatc gcctgtaaca cctcctgcga agcatttacc
     4141 agaatttttc gctcgatatc ggctgcaata tcaacgggat tccgttttct ggataacgtg
     4201 caaacatgat gcggactacg ccaggaacga ctatccacac tccccaccac agaaaagcgg
     4261 tctttttcca tccgaatatg cacagagtaa tttttaaact gcggtgacgt cagttttata
     4321 cgagacgaac aatcatcaag tttgttcacg cgccagccgt tccccaggat acggcagaca
     4381 acttcaaaga cagggtgata ttgttcaaaa aaagagttca tctgtttccc tttttgctac
     4441 gtggctgctg ttcccgtctt tttgggttcg atgccccaaa agacgggctg gctataatat
     4501 cgggggcttc tcgcccccgt tctggttacg ctctggtttc cacgcgttgc caccctgtcg
     4561 ccctgcgctg tccggttgta ccgtattttg cgcggatttc ttctatcgtg tgttcttcac
     4621 gattccagta acttttatgt tcgtctggac gataaaacca ttgttttttc tttgccgccc
     4681 atttacaccc gatttctttt aaagtttcct tatgtgtaat ggtttctcca ctaatccaga
     4741 cccagttacc tatcacttca aataccagac cagataaacc agaaagaacg tttaatactt
     4801 tttccaggtc atcaccgtaa ttatatcgtg catgttcatc agtgctctgg aactgattta
     4861 ttttatcaat atttgccatc aatacatcaa aagctgcatt taccgctttc atcagttcag
     4921 cccctaacgg gttacgatct ggatgatatt ttaaagcggc ttttctgtat gctgctttga
     4981 tatctttttc agttaattcg ccggataatc caaaaacgtt taatgcttcc tggatattca
     5041 tttttttaat ctcctgccct gctgggctat tgtgagaggg gccattcccc tttcgatgaa
     5101 acaataatac gacctttaag tcgtatttgc aagttttctc ccgttttttt actcgataag
     5161 tgattgttat cacgtttttt aatccgcgta agcggatgga aggggcgaac gaaaatacca
     5221 gggcagcaca ggagccacat cgccccgaag cgcggcgcag ccgctgacga acgtaccagg
     5281 gtgcacaggc catcccttca ccctgcaaag cccaactgac cagcaggcca tgattatgct
     5341 gatttgcgcc gcagaatgcc gcagttagcg cgagcgcaag cgagtttacc ccgccctggt
     5401 gcattgcagc atggcggggc gctgtactgc gcgtgtgagc gttagcgaac tacgggcgca
     5461 atgcaggaga actaacagaa cctccctaaa acgctctgaa tcgcatttta agcgattttt
     5521 ttcatttcgc atggttttcc tcatggttgt atcgaacgaa gcggcagagc gcgattcagg
     5581 gcttcttagt ggaagatcca aaaaggatca aataacggat catatgatct gaatctctct
     5641 ggttttgaga aaggagatac cgctcgccgc agccgaacgg caggagcgta gcgactgagt
     5701 gagcgaggaa gcggaatttt tgcgatgtga cattaggatc agtacgcacg aatattatat
     5761 ttatttcaat aagttaaagt taactaggga caaatttatg gtcttgaaaa ttgagataca
     5821 taaggcatca aatatttttt tgatgatttt atgttattga aagttatgag ttttaatgat
     5881 tgatgatgtt tgttttagct tgcgggtaat aatcatcagg ggacagattt atggtaagga
     5941 accatcatcg ttgctggttt tgttgagtta tccacagttc ctgaatattc gcacgcatta
     6001 aaagccttat cttttcttgt ttttcttaaa aacttaaaaa cttagagtag ctctaattta
     6061 ttgattttaa gcgtgttttt tgtctaaaca tgagagcttc ctcggttaaa catgataact
     6121 tcctcggtta aacatgagag cttcctcggt taaacatgag agcttcctcg gttaaacatg
     6181 agagcttcct cggttaaaca tgagagcttc ctcggtgata tccacaaaat gtgtcataag
     6241 aatactaatt cgttgttctt tctggtgaat ctattttgaa tctgttgtta atctgccttg
     6301 aatccagtgt ggattttgag catggattac ctttgtgaga taaatcacag atatgaaaca
     6361 tgagaagata ctcggttaaa catgatattg attgtgttgt aatatcatgt ttctggtgtt
     6421 aaagtctgat tatcaagagt gttggaacaa tgagaatgac gacaaataag acttcccttt
     6481 ctcgcttaac aaaagtgaga catcgaaatg aattgaattc aacgctgtca acattgccta
     6541 tggctgctaa aaaagtctta tttttagcca tgtgccagat aaactctaaa aatgaattcg
     6601 atgatgatca catattttat gtgacagttg ccgattacat taaatgggtt caggttaagc
     6661 ctgatgcggc ttatcttgct ttgagggatg gctctaatat attagatacg acgcttctta
     6721 agctgaaaca tgatgaaata ttagaactga gtagtgattt gggatttaag ttcactaaaa
     6781 gtaatgtacc tgattcaatg aatttgagtc tgactgtttt ttctacttat tacaggaatg
     6841 aaggtagagt ggggatcaag tttacgaaag aagcgaaaag atttttatgt aaacttattg
     6901 gtgaagaaaa acgttataca acgcaagttt tattatctgt tgttcgactg acaagtgtta
     6961 atgctgcatc actatatcaa ctcattcgta aaatatatag taataattct cgcgcgaata
     7021 gttttgaaat gacaatagat gaacttaaag atgaattgaa tctttataca ataggggcgg
     7081 ggggggtgaa ggattataag tatccagatt atcctgcttt taaaagagat gttcttaata
     7141 aatcagtaaa agaaatcatg aaacatacgg aagtaaagaa cttaagtttc gtagtttcag
     7201 aaaaaattgg gagaaaagtt tataaattaa agttctctta tacaattggt tatgagggcg
     7261 ataccaggga agactcagag tttactaata tgtttgataa aatgtaccca cctgaaaatt
     7321 gaggtcataa caatatgaag gataatatcg tagattttca aagaatcagg gacagcatga
     7381 atgatcattc aaccgatgtt gcaaatgatg ccgtttattc tgacaaaaag aaaatatcca
     7441 ggttctttta tctgctgaca cctgtcagat accttctggc tgcttccctt tatctggttg
     7501 ttgttattcc attggggatt cttgcgggat ttcgtttctt gttgcagttt ttaggcggta
     7561 tcgcagtgat gggtttaact atcgcctggt acatgggtgc agatgtcagt agttacgttg
     7621 ttcttgctgc atggatcgcc ttaactgttt gtggttgcgc agagcagatt tttgaatggt
     7681 ggatcgaaag ccgttttgcg ttccgtcttt ttggtatcgg gagaacgccg gaagaatgag
     7741 cgccgatctt acagacagta aagaacaatg caggatagac aatccgatgt caaatgttaa
     7801 catttgacat cggattgtcc aaaaacgatg tttttgcctg tgcctgccgc aggctctttt
     7861 aaaaggaata tgaaatgata tttaaccgta ataaaaaacg agatgaacaa cataattctg
     7921 ctgttgtttt gccatcagct gaaaatgtat tctctgattt tattaagaac aatccagctt
     7981 tgacaaccaa tgcttttaca gccattgggg aggttgattg ttttactaaa gtacccttac
     8041 tctcaaataa tgaatcagag tttttaggca ttctttcacg taatattata cctgattatt
     8101 ccgtttttcc caaaatacgg ctcattgaat ttgttcgtcc tcatggtagc gaggaagctg
     8161 taaaagattt aatccgtgaa gtgcagaata taacctgtga ttttgtcctg aaatcatatg
     8221 atgaaacagt cctggctgtt atccagtttg gtgaaaccgc aaccgtcaga cagcaaaaga
     8281 aaaaactgat tatccagcgc gtgtgtgcta tgacaggaat ttcttttttc gaatttaaaa
     8341 acactgtcga tatgatgggg agcgaagatt tttgtcagtt cctgcgggat gatgaagagt
     8401 aattaaaaat aagcccacat atttgcgggc ttaacaggct ctttattagt acttgctgca
     8461 tttgtgatta ctggcaacac agttttcact gggcagtttt tgcggtcgct tttaattatg
     8521 gttagtggaa ctcagacagg taactcgacc tctttacata ttaataattg atagttttac
     8581 ctggcttcct tcaacattta ttttgttgag gaatttattt aaatacgcaa tatctggagt
     8641 ggaaccgcat attttcatca attcttgacc gataggcgta agtaaagccg ttcctattgg
     8701 tagtttccag gttgatgaat catcgctttg aaactcaact gaaaaaaccg ttccgtaata
     8761 accgatacga ccgtttttac ttttaaagcc gattaaactt gttcaccctt cttaaaaaac
     8821 acccacgcaa gccctgccga catcgcccac gcaagcatca tcgacaccac cgtatggctc
     8881 aaaaaatgat cgccaataat catcttatag cagcccatcg cccagcccaa tgccatcacc
     8941 acgatgatga tcgcaccacg acggcggcgc aaacttggcg caaacgcaaa ggcaaacagc
     9001 gcaaatccgc tactggcatg cgccgcagga aagcacttat caggaatggt gttacgcata
     9061 ctatcaagca tcggcaaata cggcagcgta ccatcaaaaa tcgtcaaatg cacagggcag
     9121 accacatgag tatatgcctt caatgacgcg acaactgtcg gcactaggat caaagtcagc
     9181 accagatacg caagctcacg cacgcgaaat tttgtcactg ggacaagcca cttggcagtg
     9241 atagcattgc cctttttctc atgataagca cggcaaatgg tcgcaaccag caagtagatc
     9301 agcatcgcca tcagcagctt ttttagtcca gaatacagta gcaaatctgg caaaaaagct
     9361 tgcttggcaa ccatccaatg ccccataccc agataaaacc aatcagcgac catcagatta
     9421 atctgactgt gctcaagggt cagcgtggca acgatcgcca tgacaagagc gatactcatc
     9481 tcagcaagta ggcgtttatt tgataaatac ggcataacaa accccacccc accgcccata
     9541 atacgaatgg agtgtgcggt gggtttggaa aaaatacagg gagaaatcag cggatgaatg
     9601 cggtgcggtc tttgactttg tccgcggtga catcaaacag ctttaataat gtcggcgtga
     9661 tcgcgtcatg ggtcaggacg gtatcggttg ccattggcgt gatgccagtt tgcttatccg
     9721 tccagaaaaa tgcaggcaca ctgcgctgtt cttttggtgc aaaggcattt ggcataccat
     9781 gtagatagac accgttctca cccagacttt cgccatgatc gctgacatac agcattgaga
     9841 catcataggc attgctgtgc gtctgcagcc actggatact ttgagcgatg aaatcatcgg
     9901 tggcaagcaa ggcattgtca taagcattga tcaaggactg atgttcgcac ttggcaagct
     9961 cattaccttc acacactggc gtgaatttgg caaacttttc atcatatcgc ttaaaatacg
    10021 caggcccgtg attgcccatt tggtgcagca tgatcagcat atctttgccg ttattggcag
    10081 cgacaaagtc atctaagcca acgagcatac cgacatcgcg gcattcgtta taaggattgg
    10141 tgttgcagat ggcgttgttg gtcgcggatt tataatcggc aaattgcgct tttggcagct
    10201 tatccatcac gccttttgag tccgaattat tatcacgcca caagatactt acgcccaagc
    10261 gatccagcgt atccagcaca ttttcttggt atttggcggt atcgacatca tactcatccg
    10321 cgcccagata gctgaacata cacggcacag aatacgccgt cgatgtgccg cacgatgtga
    10381 cattgctaaa attggtcacg ccatcgatct tggcaagctg tgggaaagta tcgcgctcat
    10441 agccattgaa gctgacatga tcggcgcgtg ccgtctcacc gacgacgaac accactaggc
    10501 gtggcttacg catatcaggc ttggttgctt gtaccgcgtc tttggcgtga taaatggtat
    10561 cttttggcgc actggctttt ttatactcaa tactggcaag cttacccacc gagtagattg
    10621 gcatgatcgg attgacatag ctacgcagcg gcttatgcac gcgaaagaaa ctggcataat
    10681 gactgctgaa cgccaccaca ggcagtaaaa tcagcgcaag acttgccacg atcaagccca
    10741 atcggcgcat caaacccttg ccccaagtcg gataatccac cttaacaaaa gccacaagca
    10801 aacttggtag cacacccaaa ccaatgatac gcatgataaa cgctgcgttt aatagatcct
    10861 tggtctcggc ttggtcggtc tgtagggcat tttggagcat ggtcgtatca tagaccgtgc
    10921 cataagtgtc agtaaaataa ctggtcaccg cgcccatgat taatagcaaa atcaacacag
    10981 gctttagcac atagcgatac gatgataaca gcgtggtgat cagtagcatc gcgccaaaga
    11041 gcacgacagc gatcgtcagc acaaagccga gattgtccgc gatgggatag gtttggctga
    11101 ttttatcaaa aaaggtaaga ttggcggtcg cggtcaagaa aacggcaaca ctcgccacaa
    11161 gaacaaacgg actgaccgag cgtcggtacc acacagaagt atgctgcatc atgagaaact
    11221 actcaaaaaa taaacggtgg gataattgcg gcaatcatac tgcaattttt taagaaatcc
    11281 agtacaattt atctgatata aaaaattatg cgatacagaa atatttcaga aattttatta
    11341 ggcaatcatt gcgcaatccc atactgaata tacacttgag agtatttata atttgtatct
    11401 taaactataa ccaatgcctt gttgaataac gcctaaggag tctaaaaccg aaagtttatc
    11461 gaaagttata ccttcagtat ctccattctc atcggtaaat aaaattggag tgagtttgtt
    11521 tgcctgccaa acaaactttc caaaataagt aataaggttc gcttcttctt tgcttatagt
    11581 ggataatagt tttaaggttc tacgactaaa cgaacctttt gactttgctt cttcggataa
    11641 aattcttccc caaagcattt gcatttgttc gtcactaata tcctcacact ccctgaagaa
    11701 agcctctatc caatcttcgt caatatcaga aacattatca ctctcagata gactttgtgc
    11761 tgcttgcatt gttatatttt caatgttttc ctgtcgtttc gtttcacgtt tgagaaaacg
    11821 ctcaactgcc cgtttttcta ttccctcaag ctctaaccta gaaattagct ctgtgcgttt
    11881 agcttcagct tcagccttcg cttttttcct gattcttgta ggttcataaa gcacaccaat
    11941 agcatcactt attttttcaa taagttttgt tcctggttct gataatcctg ataaacttaa
    12001 atcgataagg ctcatctagt gctcctaaat acccgtgcaa caactgtaca agggtatttt
    12061 attgcaagag taactaaaaa tgaatcacaa ctacatttaa aagtgatgaa gttagtacat
    12121 tcagataagt atctaaaaga aaatgataaa gagtttattg ggccacttgc tatgattaat
    12181 catttctgtc agctctgaac cacaaattaa tgagttcgtt ttcgtccaga tcctgataag
    12241 ccagtaatgc tgctttgatt atttttgtct tgggacgatg cagtcttttt gattcgttat
    12301 caatgaattc aagcaattca ttcggtatgc ggaatgaagc cagttttgtt ttgttctctg
    12361 tggggcgttt tcctgcgtcc tgaacaaatt ttgtggcgtt cacttcctgg ttttgttcta
    12421 gttctggtag ttccagcttt gccatgatgt accttctaat ctgattgttt cacactaatg
    12481 tatatcatga tgatgtacat tagtgtatgt cactatgatt tacagttcca gttctttcag
    12541 caagagttcg atttgtgctt ttgcctggct ggcaccgcta acattacttt ttaactcgtg
    12601 aacccccatt ccctgattca ttgctcttac aaaggcccgg agaaaagaaa ccgtgctttt
    12661 cattggttta agccagtaat catggctgtt gagagagtct cttaattctt gttgttcact
    12721 gaacgtattt ggctggcatt tatacaggag cacatgtgca gccagcctgg gatttatttt
    12781 ttgcgcatcc ctgacaattt ttgtcacagt ctgaagactg tctgcttcca cctgggcaag
    12841 cgggtcgatc gggacaatca caatgtctgc aacttttagt gcagttctga actccgtgct
    12901 gtcatatccg gcagtatcta taatgaggat ttctgctaca tctgccattt ttgttatttt
    12961 ggcactgatg tcgccatagg cttcatttaa tgcgacgggc ggtaatccgg cctgttctct
    13021 gcgtttattc cattttttgg tcgagccatt caggtctgtt tcaacaagcc ccgttctctt
    13081 tccctgttgt gagaggcaaa cagttaagtt ggttgccaga tgtgatttac ctgtaccgcc
    13141 tttatcacca ccgattacga taatcatagt accccttgta tgtcacagtg atttactcat
    13201 gtgtatttct atgtgatgta cgcatgcgta tgtcacatgg acatactata gtgtatgtca
    13261 caatgaatta caatgatgta catcatgaag aaatacatta ttgtatgtca gtgtgatgta
    13321 cccgttggtt ggtcacttga aagcaaaagt gacagcgtta ctttcggtat cctcccttgc
    13381 tgcgaaacct tgtggcaata cagcaatgag tatgtttagt tacaacattc aaaattaagc
    13441 gattagattc cgcccgtacg ggcggggcgc gccactttct gtagtgggga ggggcaggga
    13501 ggttatgttt gctggatgag cggaggatgg aatgagctat tagaatgttg taactaaagg
    13561 gtatcccaat taaaggccac ttacgcggcc tttgtctgtc ggttcttcgg tctggtgaca
    13621 taccacgata aacatcccac agcaacactc ataagcattc cggataagcg atcatcgatg
    13681 ccaggaaaca ggcaaccgac aaacatcgca acagggaaag gaagaagtaa acagcgcccc
    13741 aaaatgctca taaaatccat aaatcctcct tttttgttaa agggcaggaa gcggttcact
    13801 tcctgccctt agttacgttt ccgttgtcat caatcgatga attggcggat cagttccaga
    13861 actgcaatca gcgcgtttgc aacggcgacc acagctctga gaacgatgat taacatatta
    13921 atcatccgtt tctccagtaa aactggagga aatcaccgtt gcttgctcat acactgcctg
    13981 tcacaacggc tctctcgcat tgttaggtgt agagtgacct cctcctgcca gagcaccgaa
    14041 tacagcacca cctgtttatc cagccaggac tttaaaatcg ttcatacccg cagatacggg
    14101 aacagcagga ttgcaagcca actacatgac taactgactg attatacgct acacaaaaca
    14161 cccgttacac cactaaatgt ggttccttaa ccacatttag ttgctttaca gcaccatagt
    14221 gaataaaatg taaacgttag gtgtagagta accttctccg gtcagagcca ccaactcaag
    14281 actggaaaac gcaaaaaagc ccgattacca gtcgggtttt tttgtgcctg tcgttcggct
    14341 gtagttccgt tttttctcct tcatttgagg gatttttctt tcattttttt tgttgcttcc
    14401 aatactgcct gtcgcgttgg ccaacagctt gacgcgttac cggcattttc attactcaat
    14461 atttttcagt gaattaaaat gcaacagcga cagaaaagga cattcagctt tttagatgaa
    14521 tgctatagca acggtgtgct acgtaaaatc tgcgaaaaaa gcaggggtag ggtaggttat
    14581 ttttcacgta gcaacgccat ctggcactgt acataggtat gtcacacaga catacctatg
    14641 tgtatgtctg tgtgaggcac tgttgcaaag ttagcgatga ggcagccttt tgtcttattc
    14701 aaaggcctta catttcaaaa actctgctta ccaggcgcat ttcgcccagg ggatcaccat
    14761 aataaaatgc tgaggcctgg cctttgcgta gtgcacgcat cacctcaata cctttgatgg
    14821 tggcgtaagc cgtcttcatg gatttaaatc ccagcgtggc gccgattatc cgtttcagtt
    14881 tgccatgatc gcattcaatc acgttgttcc ggtacttaat ctgtcggtgt tcaacgtcag
    14941 acgggcaccg gccttcgcgt ttgagcagag caagcgcgcg accataggcg ggcgctttat
    15001 ccgtgttgat gaatcgtggg atctgccact tcttcacgtt gttgaggatt ttacccagaa
    15061 accggtatgc agctttgctg ttacgacggg aggagagata aaaatcgaca gtgcggcccc
    15121 ggctgtcgac ggcccggtac agatacgccc agcggccatt gaccttcacg taggtttcat
    15181 ccatgtgcca cgggcaaaga tcggaagggt tacgccagta ccagcgcagc cgtttttcca
    15241 tttcaggcgc ataacgctga acccagcggt aaatcgtgga gtgatcgaca ttcactccgc
    15301 gttcagccag catctcctgc agctcacggt aactgatgcc gtatttgcag taccagcgta
    15361 cggcccacag aatgatgtca cgctgaaaat gccggccttt gaatgggttc atgtgcagct
    15421 ccatcagcaa aaggggatga taagtttatc accaccgact atttgcaaca gtgccctgtg
    15481 tgatgtatac ttggcgggtt attctgcctg ttccggctta gttttctcaa tgaggaaatc
    15541 ttccatgaaa tgcccctcat caagcagctt ctgtaaagca agcggacgct tgccattacc
    15601 agaccattct ctgatctcgc cattttcatc cttaaagcgg tatttagcct ttcttactcc
    15661 gcctttggct ttccgcctgg tttttactgt atctgctgtt acaggagcaa ggagtgattc
    15721 gggatcaaga cctaaagata tgatgtattc aatggcctgc tgacgtttgg cttcaagttc
    15781 ctggcgttca gccgcttcac gttcagcatc ttcacgacgt tcttcaataa caacgttgag
    15841 cttttcctgc atttcgagca actgctcaaa atcaatctca cgggcaaaaa cacgcaatga
    15901 acgaatattc atcatagtac ggctgataat gccgtattca tcttctttag tcagttcgct
    15961 catataatta atcctcttat ttagtgtacg tacttccaga cgccggaagg caccttatca
    16021 taaagtttat tcatcaccag ttctgctcgg cgatgatctg cggcagaata aaatgcctct
    16081 gattctgata aaggcagttt gtaacggtta atctcaataa ctttttcaag agtatctctt
    16141 gatgtacatt ttcttaactg aaaaagccat tcctgctttg ttttcacttc ttagcccttg
    16201 ccggaaaacc cagcttccct gttttcttat cctcaaggac aagaactgta tcatacgttc
    16261 caccactttt ctttttaaat cccttaatca aatcggtttt ccctgattta accagttttt
    16321 cggcctgtgc ctgggtgatt ttcttaccag aaaactcact ccagatttta aattcacatc
    16381 cggtacagaa ataacctttc ggcctgataa caatatgttt accacaggaa gggcagggag
    16441 agtccaggcg ttgaaactgc cctgctggcg cagcgggttc aatcttcatc tcgcccaggt
    16501 caacatcaga aatcatgcct gtcagttcac cgtacagatc attaataaac tgttcaaccg
    16561 tcaggtcgcc attttctatg gcagcctgct tttcagacca taatgctgtc atatcaggat
    16621 taaccgctat accaggcagg gcatcaataa gcgcatatcc ggtatcagta ggaataagtt
    16681 tccctttttc cagcgtgata tagtttcttt tcttcagcgt ttccagaatg gctgcgcggg
    16741 tagctggcgt accaatgcca ccatgttcat cttttttgtc tttatcctta tccttcaaca
    16801 attttttaat tgttggatca gtgacaaaat ccgcgacacg aacaagcgca gcaagcaagg
    16861 aggcttcggt gaataacggc ggcggtgttg ttttcttctc attaacaata acttcttttg
    16921 tcgtcagtgt ttctcctgtg cgaattttac agagcagttc aaaagcggaa tcatcattat
    16981 cttctgattc accttcgtct gtggtttccg cgccaagaaa cgcctcaaat ccgctgtcag
    17041 ttgtttttct ggcacgggca tagaacgact catcaccaca ctgaatggca accgatactt
    17101 cctggtatgc tttttcaggc atgaactgaa caagatagtg ttgtgcgatc gccaggtaaa
    17161 cattgcgctc gtcggtgctg agtgcgttaa catcaggcac actggcggtc gggattatcg
    17221 cagtatgcgc agtcaccttt gcactgttaa acgctttgct tttacgtgca gaatcaatat
    17281 ccagcgactg aggaaagact gatttcaggg catcgataac ctgcggcgct tcgctgaatt
    17341 gttcatctga aagatatgag cagtcagagc ggttatacgt aattgcttta tatttttcgc
    17401 gtagttgttg cgtaatatcc agcgtttttt gtgccgtcat tttaaacttc ttgttcatgt
    17461 attgctggag tctgaccaga ttaaacggca acggcgcagc cgttttttta tcatcagttg
    17521 ctgctgcttc aactgtagcc ggttttcctg caagggatgc agccgttccg tctgcccacg
    17581 ctttatcaag taatttacgg tctgtcagcg gagcaaattc ccctggcttc cagttcgccc
    17641 tgataacatc agcaccacgc tgaaagactc cggtcatggt gtagtaaaaa ctggatttat
    17701 ggttctggtt agcacgggta cgattcacaa tcaggccaag aacgggagtc tggacgcgcc
    17761 cgacagacag aacgccctga tatcctctgg cttttgccgg aatggtgtac gcacgtgtca
    17821 tagagaagcc atagacggca tcggcaactg accgcgccaa cgccttaagg taaagtcctt
    17881 tgaaatcacg attgtcttta agatttgcca gtgccttttt cactgccgga agcgtgttgt
    17941 cgttaatcag aacgcgcttt acgggttttg tgttgcctgc atattccagg acttcatcaa
    18001 ccagtagctg tccctcatca tcaggatcgc cagcgtgaac aatttcagtc acgtctccac
    18061 gtctgataag ttcgagaatc gttttaacct gttttgctgc actttcaaca ggctgatact
    18121 tcacgggata aagacgtaaa ggaagcgttt caaccttcca ggctttgtat tcaggattat
    18181 agttttccgg cggttgtgat tcgataatat gaccaaaaca gttagtcaca atggcgttat
    18241 cactttcaaa ccagccatca tggcgggtaa aattgccacc aagtgcctta acaatatcat
    18301 ttgctactgc gggtttttct gcgataaaaa gtctcatttt gttatccttt acattgaatt
    18361 aatcttttgg cacaacggat agcgcgttct tccgatactg tatgttgcca gttatcttta
    18421 cttactactc tgaatctgcg ctcacagcca ttaaaggcaa aaattccctc acggttaagt
    18481 atattagttg caatatccca ctctttaatt ctcaaaaagg ctgttacagc aaaaccagaa
    18541 tacgaagcaa tttttgaaat gatgcattca tcagctttta ttaacgcggc aaaaggaact
    18601 atcttttgat gaccacacga aatcagaggg agtgtgtgaa tatcataata agctattgaa
    18661 tgacaatcca tgcgggtatc atcaatagct gccagccaga atcctgcctg gtcttttatt
    18721 tttctgctaa tatctgaatc tgaaacacca gggtttaata aatatccacc ataacagata
    18781 tggaaggggt gagcagattc atcaatatca ggaagttctt ttaccggatt ttctttccag
    18841 tccttcagaa caccgaattc aagagcatcc agcaaaaact ttcgttcaaa tccatcaaac
    18901 aatgcatatt gcatgtgtta atcctccagg taacttaaat agtcaggttg tgccccgttc
    18961 tttttataaa gttcttccct ttcctctata tcttcatctg cttcctgaac gctcagatcg
    19021 agggttcctt tcaaaaaggc acgagcattt tttattacat ccacttatgc actaccagca
    19081 gataagcaca ataaaatagc tataatagat ttggttactt tcatttctaa cctcagtgat
    19141 tgtaactaat catcacattt cgttggcgcg aaatgtgata cttgcagtac cctgataccc
    19201 gttggcgcgg ttatcaggtt ttaattaacc tctgacacga ccaaacttac tcatgatttt
    19261 tgatatagca gcaggatcag ccgttgaaca ctgattcaga aatgctttac gggcatcaaa
    19321 agttttactc cagcgaatgc ttcctttttt ctttttcaga atattaaaaa aatccttttc
    19381 agcacttctg cattcactcc ctccaccttg cccgactgct tttccatata agcaaagtac
    19441 cgaagcgcaa gggtcagatg cattagcatt tgttgatatt aatcctaacg ccagcaaggc
    19501 tggtaaaacc actctatttt ttccagtcat ttttcacctc attttgtgct ttaatgaaaa
    19561 ctatttttac ctgttcaggt aaaaaacttt tctcgtttcg ccattccacg actgctgttg
    19621 ccccttccat cttcaacaga tctctgattc gaaaccacag cccagcatca tgtgttgtca
    19681 ctacaatcct gtccgcatga gccagagcgt aataaaacgt cggcgttctg gcctgtactc
    19741 cggataagga agtgatctca taaacccatc ctttaccgct aacgtctgac tttatgacac
    19801 cgtgaaaatc ggggacatat ggcaatgagg gattgatcac ttcatttgcc ttttcaaact
    19861 gcacgggtgt tggctctggc ggtgatgaac aaccagcaag aatggaaatc aataaaaaca
    19921 ctaacttctt catcatgttc tcctttatgc cgctttatcg agatcaggaa catcttttac
    19981 taccagatac ccttttgcga cgatttcatt ttcaaatact ttctgtggag gcataaccag
    20041 ctttcctttc ttcctgggga aaatgtttgc aagttccgga gcaaccttca caaagtcacc
    20101 aaagaaatac tcattgagat agtagaatgc cttttcacaa cgaatcgggt tttctccctt
    20161 cattgccagg atttcttcac taaatttcag tgtaagtagt tcatttgttg ttaccagtgg
    20221 acgctcaata aggctttctg attcagatct cgatgttcct ccacgactac gacttttgct
    20281 tttcgaaccg atagttactg ttcgtgtccc catcgcttct gataactccc gcgcatcttt
    20341 aacatcagaa gcggaataaa caattttgca gggtgcactt gccagtaatg ttttactgcc
    20401 tgcataactg tagatttcct caagctgaga gccgacctgg taaacaatca acaatttcag
    20461 cttgtaacca gcaatgagac cagatttact cttgatgtaa tctacagcac caattgacgg
    20521 gaattcatcc agtagaaaaa ggcagtcatg ctttatttcc ggatcatccg ttggcatctt
    20581 ttcaagattc acctgtatag caagctgaaa gaaaatattt gttatttttt cagccaacct
    20641 ggcattatca ccagaaatac agaaataaat tgtcatccgc tttttccgca cctgccgcaa
    20701 atcaaaatca tttccatcag tagcatttgc cacattgggg ttagcaaacg gtgataatcc
    20761 attaagaaag ttgcttttga gttgtgcttt tgttttatcc tccatctcaa tgaatgcctt
    20821 aaggccagcg acaccaatat cagcaagcgt tttgtctttc ccccttaatt ctgaacgaat
    20881 atcattcatg aatgaaagaa gatgttcggg ttctgcacgc tcaaaaagct gattaatttt
    20941 agacattgag aagacaggct caatatcaag cgtttttagt ccagccttat cattcttaat
    21001 cataaaccat aaagcgacag cataagattt aaaaacacca cccgccgtct tattaagata
    21061 gctaccagca tccgcaccat ctgtcttata ggggtaaata atcaacgaaa gattttcaag
    21121 ctgattaaaa ccttcactcg ttcccatgct gacataatac aaagggttaa agcggtgcgt
    21181 taccgaacta aagggatcaa atttataaac ctcatgacct aaaatcacct tcctgataag
    21241 actggtgata ttaaaacact ccctttttgg atcgagaata ataacactcc accagtactt
    21301 cataagatta gtgatgacta taccagcacc tttaccagcc cttgttccgg ctcccatagc
    21361 actgaatgct gctcccacat agcgtatgat tttcttgtct tttataccaa cgataatccc
    21421 gtctttttcg tcaccgtcaa gcgtgaaact gttagactca cgaatatcat taattgttgc
    21481 aaatcgcgca tcaccgaaaa tattttcttt cttctcgttc agttttatca acgccgcaac
    21541 agggatgata agagacacga caaatcctgc tccaagtgca acaaaggcta aaactctgat
    21601 atccgtagtc acaacagata aagtaaggct gtctgtaaaa atatccatcc tgtacgcatc
    21661 aatggatctg aacacagcct tcaatggttt cagattcttt atctggctga agtaaagcac
    21721 aaagaaaata aatgaacctg caaaccatgc cgcaacaagc ataacagcga atataaaaac
    21781 agattgcgac ttattaaaag ttttcacatt cagccccttt gtaatagatg tcgctcatat
    21841 gcctgacaac accatccctg cctacatgaa caacaatatc aatactgtcc ataatgattt
    21901 tacgaagaac atcaaaagga agattctgac attctctgtt ctgataacat tttgtcacca
    21961 tctgaatgat ggcatctttt gccgaggccg cgtgaatgga cgtcatgctt ccactgtgac
    22021 cagaaccagc aactttcaca aaatcccagg catcgccacc tttaatttcc gccagtaaaa
    22081 ttctgtcagg tttcatcctc aaacaggatt tgattaattt cgctgctgtt atgatagagc
    22141 cggaatcact gccggattcc gaagggtaaa aaagatgcac ataattttta tggataaaaa
    22201 atttgatttc ctctgcatct tcaatcgtaa tcagccgtgt attcaatggt atgaaatcga
    22261 taagactctt catataagtt gttttaccgg aacccgttgc tccggcaaat acaatggttt
    22321 tccctgctgc tacggcaagc tccataaaag cagcgatatt tctcgctctg aataaatcaa
    22381 gaagctcatc atcgtatgtc ctgtgttttt ttcctgactg gacataatca taaaaaccgt
    22441 tcgccacata ttctttatgt gttatctgcc gtgtcgatgg tttacgtata gtgattgaaa
    22501 tagtatttct ctcacatgca ggaggaaaaa cgacctgtac acgttctcct gattccagtg
    22561 ttgctgaaag taatggcttg gtctcgccga tttcatctcc ccgaaatgat gccagcgtat
    22621 gagaaaaacg tttacaaaaa tcaaaggtca cactgtcatt attatggaat gtccagtcac
    22681 cattaatttc cgtccagatt tcaccaggac ggttgacagc aatttctgtt agcccttcaa
    22741 tatcaagaaa agactggaat acttgatttt tataaaaatc gagcgattta ttgctaatgc
    22801 tgacaggaat aacgccactc atactatttt acctttaact catagatatc agaaaaatca
    22861 atgtcttccc cgaccataat agtgattatg tcaccctggt ttttatacat tgttggagga
    22921 atatttatcg aattctcaag tgcgacttta gccatttcag ccattgcctg tcgtgagttt
    22981 tcggtataat ccacattacg atctttacca ggtgcattat ccgccgccgc cgccgctaca
    23041 tcctgaacca tactgagcat aagagaacca ccaaaacgct cccagaagtg agaatcgatc
    23101 catccatcaa tgcccgcttc tcccagggga ccagctgctg ctgtatttac catatcgatt
    23161 cgtttattat caggcgtccg caactgctcc cacataacga acattctgcc ctgtccatga
    23221 ttcagcgttc cggtctggta acgaccaaaa gccttagttc cctgttccag taattttgtg
    23281 tggtgattag cactccatac atcttctgta aaaacacaac tgatacgacc tgcaacatca
    23341 gaaacaaagc gtgtggttaa agcacacggt ataagcctgt tttcctcaat atagagatca
    23401 ggatcgagat taatcgcagt tactttcatt cctgatttac caggcacatt ttcttttgat
    23461 tctttccttt cttcctgtgg ctctgatgtc tgcgatgtcc tgctgctgcc actcgcgcca
    23521 gtctgactcc ctccctgacc agcaacaggt attgacaaat atttcctgaa cccctcctgt
    23581 ggcacttctt tatgaccgtc agaaacagta ttaccagaac cagtagcgcc tggattgata
    23641 attgctttgt tctcaacagg gtcaaaattc tgaccaagac cagtacggat tttacttacc
    23701 tgagaaatgc tggtatcgcc tgttgattct gatgctttct gctggtcatc tgcaaaataa
    23761 tttttatatg ttttcagcgc aaaaatacca ataactaata cagccatcag accaaacaga
    23821 aagccagaac gcatacgatt atttttgttc ctgatatcac cgatatcatg aacgggttta
    23881 ctttccagct ttgactgatt cgcatcatca actaaatcat ctgttttttt catatcagtc
    23941 attattcacc tcaacacgtt ctaccgcagg agaagatgta ttcctctggt cggttaatac
    24001 ttttccgaaa gatttattca caacaccaac aacgctgttt ccatagcgta aaacaaattt
    24061 gtcattaacg ttgtggataa ccataatttt atacttgcct tttgtttcca cattaaaagc
    24121 aagtgtctgt tcctgaccat ctcttacagc aaatggagct gggaatactt tccctgagtt
    24181 aaaacctaaa aaggtaaata tgccattatc ataagcaaaa tcaggggcga tacgacgact
    24241 gtcatatttt tcattgactc gcatgaaata attccagttt ttaggcgcat cggctttttc
    24301 aaaactttca gaaatcagtt tcttctgtct gagtttttcc tgtttttctt ttgccagcct
    24361 tacttcttct gcattctttt tcgctatttc tgatggatag cggaattgta caacataagc
    24421 aggttgcgct tgtttttctt ctgacagaag gattagatcc agactgtaaa tccgctttgt
    24481 tgttctgaca aaaagattcg tatcccattc cttttctgtt ggctggaaaa cctttttcag
    24541 tttttcgcct tcatcgcctt cctgttcctg aacaacggga cgcggattga tgtaaacaac
    24601 attatcatcg gttgtgattt cccatccggc aggaaaacca gcctttgcac tgataacagc
    24661 ctcaccttca tcaaaaacaa ctgatgtgag aaatcctgtc tttgaccgga taacggtcgt
    24721 attcgcaccg ttataactca cagtctgcat ccttgcatca aatccagaag gtaacggagt
    24781 cgctgctgaa tacacaagcc caggaagcaa taaacatgta gcaataaata atttcttcat
    24841 cattcccccc tgacttcccg atctgtctgg taactggtta cagtaaaacc gagaggatta
    24901 agctcacgac tggaactttt aaccgacttt tctggttcaa aacgatatgt cacacgagcc
    24961 gtccagtatg aaactgaaac ctgtccggtc gtgaagtttc tcgtcgtttt tttaaagcgc
    25021 acagaggcca gtttatctgg cgcggttgcg tcagaaataa tattggagat gacctcaacc
    25081 gcaacgtaag aaccgttatt atgataaatt ttatcaggag ccatatcgct gttatacaga
    25141 cgaagataat cgtcctttac tgtattcgag ctatatagct gtacagtctc ataatcatac
    25201 tgaagagacg gataattata accttcacgt aaagtaatat acgtgtttac aaaataccgc
    25261 ccaagtgctt cagattgcag gatcttttcc tgtttaacct gagtaatcag ttctgtacgg
    25321 cctgtttttt cgccaacagc cacaatagca agctcttttt cttttaatgg cacaagaaca
    25381 caaattgcag ccccaagaca taaggacagt aatgatgctg ccactgcaac acgccatgca
    25441 tttttcttag accgttcatt ttctgcatag agttgtcttt cgaaggattt agctgtctca
    25501 atcttctttt cgattttttc actcataact gattacctgg ctgtggttaa tgggttccag
    25561 ttcgccggaa acatcagaag gaaggttatt ccttgtggta catccggaaa tctgaaacag
    25621 gaaaaacaaa agaatcacac atcgcataaa ttcaccttat taagcgttca cgaacacctt
    25681 taagagataa aggccaagat gaagaaaaag aatcccacca ataagaagca aaaagcgaag
    25741 atccataccc tttctccatt tccccgcaag ccctaaacca agtcttattc ctgcgaagca
    25801 ggtaaacact cctaaaagaa ggattaggac aaaataaagt atcatgacaa aataatgaag
    25861 catgtcacaa ccagctctga ctgattccac ctaagacctt aaataaggta attcccgtga
    25921 ttaaaataac aagctgggtt attagctttc tcttcctgct ccatccggag gtgatatgtt
    25981 tatcaacgaa caccagtatc cagttcaggg acatcacata aaaaaaacgt ttcattattt
    26041 tcatgcggcg ttcctcgctc gtgctttttc cagggatgca agtcttctcg ccttcatccc
    26101 caaagcacct gtcggagcca gcgcctgata tcccttttca cccgcccatt cagcggctgt
    26161 tcgcgcacca cgccccatca gattccctgc tttccctgat aaagaattca tgcccgttct
    26221 tccggccatc cctaagccaa aacctaaacc agcacgaccg ccaagcatca gagacttacc
    26281 agtagccata ccagcagcac ccagccccat catggctgcg ccctgaacag caccttcaac
    26341 acctgcacct gctaactgga cagcaaaacc tttagctata agaaccaata aagcccccaa
    26401 aaacccagcc ataaagccca tagcacctgt agatacaaga tttacattcc ctgtttgtgc
    26461 agcacgaata gcatgggaaa ggatcatccc ttgaaaatcc attgctatcc gaatcactaa
    26521 actggcaaat agaactgtca gaatactgga gaataacgat tgtaaccaat tattaaacat
    26581 gctccgaata aaaccaaaca tgagacaaaa gataaatatc ggtgctgtaa taatcaggag
    26641 tttcatcgtt acatctgctg ttaaaaaaac aaccacacta acagccatta aaataagcga
    26701 gccagtccat attaaaaact gaccaactac accttgatct ttaacatatg ttgatttatc
    26761 taaagagtat atttccgcac caagattttg cgtacttttc cataagttat ctaaagtttg
    26821 ccagacactc acccctccag aaaaaccatc tttcatgcct tgcaacgcat cagtagccgc
    26881 agttaaatac ccatccgcat tagttataaa catgattatg attgcaaatt ttgatagatc
    26941 ccatactaaa tcctgcaagg gcgtctgagt tttactggca agtatttgat atcctttcca
    27001 tagtacatat aacgtaaccg ataccgttgc taacgacata atatcattag caaattgtgt
    27061 ttgataactg gagctgattt tatctaccga atccataacg gtagaattat atttaacgaa
    27121 aaacccctga gccatatatc caccttttaa tcaaaagtta atggttcagc ttctttctgc
    27181 tgtttaataa aggcctcttg ttcttgtgtg accaacatct catgatctgc tttattttta
    27241 ttattccaga catcatactg catttttatc gcctgcattt ttaacgactg cgcctgtaat
    27301 gcgttagcca aatcctggga ttctttgata tcctttgaag cctcaattcg gctacttaaa
    27361 ctctgaatct gagacattgc acttgataac tgcttattga tctcatttcc ctgttcaata
    27421 ctggcagccg ttgacacaat ccgtgcttta cagagattat cattacgttc atagcccgta
    27481 ttacacatat cgaaggctcc atacttgctg aacagatttt tagcctggct gctcaatgca
    27541 ccttcgggat tactggtaaa atcagaaata taactgttcc cctgcttata aatatttgtc
    27601 agttctgatt gtagattact tagttcattt gtgaatgccg caatattcct tatacctgtt
    27661 gccgtggcta actggtcttt atatgcctga atctgactct gataatgttg cgcagtttcg
    27721 gaccattgtt tgagtcgttc tgtccatctt gcggcttcaa cagcccattc cggactggca
    27781 tcaatagcaa ccggaattcc tgcgctacta taaaatgaag ccgtcaataa tgatatcagc
    27841 atcaatgttt ttacacgttt cataaattca cctgtcagat tgcccgttcg agatattcag
    27901 gaacccagtc atcaggctcc attccttcat gataaatact ttcaaaaatt tccagattat
    27961 ctgcactggc agacaatatt ttcagatatc caccaagtcc cgataaatcg agtgtcgcaa
    28021 gtgctgaaaa tgatttacca tccccctttt taagactgct ttttttaatc aggaactgtc
    28081 tcgacattgg atcaagattt ttaacaatat taaattcttc tggtgtcagc ttaagccctt
    28141 ccacataatc attgtaatcg gcatcagggt tagccagata aatactggtg ctgcatactt
    28201 caaccacagc ccgtgaaatc ttattcttca gtatttcatc cggagactga gttgccggaa
    28261 taaccagccc gttcagctta cgaattgttt tcagcttgtt atagacaaag tcgctgaatg
    28321 cttcatcctg tagccatttc cagaactcat ccaggaagat aacaagacgc cgaccgtcca
    28381 gaagctgcgt aatgcgatac agcagataga aagtaattgg tgcacatacc atcggatcat
    28441 caagaaactc ggtgccatca atgccaaaat tattgacatg ctgaatattg aatgtgtctt
    28501 tagcattatc aaaaacccag ccatgagcct gaccattagc ccattgggac aaacgaagga
    28561 taatcccgtt ctcctgctca tcccgatcat ctctctgcat aagatgctca agcattctgg
    28621 taatgccata ttcccgcatt tcgccaggag gaaaatccat cacagcatca acactttcgc
    28681 taataagcaa tctttctctt gtcgataatc tttcaccatt tctggtacac agaatctcca
    28741 tcagttgctt gacaaaaata cggttacgtt ttgttgcctc cagagcaaaa ggattccatc
    28801 ctgtcggctc accgcttttt acggtgtaat attccccacc aagcattcgg atacataatt
    28861 cagcccctct gtccttatca agaaagacac acgttaactt cttatttttt gcagaatcag
    28921 caaaagtttc ggggttattg tatttctgta atgaacaggc aagatatgac agaaacattg
    28981 tcttacctga acccgccgtt cctataactt tagtattagc aagattcttt tcacctgttt
    29041 catctttaaa cagtactgag ttatgtaaat tcagataata cgcctgtttg cttggtgttt
    29101 tgagaatagc aaccgcttct gtccagcagt ttttatcgcg tttcccctgg tagaaattat
    29161 ggaatgatgc cagttcaaca aaatttacat tcgataccgg agataaacgc ggccttaaat
    29221 gaaaaaccgc cggaagttgg gcaaaatatg ccgctggcaa tgacatggtt gacaatgccg
    29281 gaataatgcc caggtcagta aagtctgccg taattttact tacagattcg tcaagctccc
    29341 tgatactgtc cgccattacc attagcgtga aatggtagta accaaaggat atatcaccgg
    29401 acacaatatc attttttgcc ttttccagtt cctgcaattg agtaaccgca tcatcttctg
    29461 tactctttaa ctgtttttcc gcacgtttaa tggtactcaa tgcttctgat ttgctcatgg
    29521 atgtatatga atgcgtaata atatagtcag catcagaata ctggagcaca tcaaaaacac
    29581 cggatgcagt ctcactacag aaatctttaa tttcaataga acgaaagaat ttatttccat
    29641 caatgcggca tatctgtccg gtatcatgat taaaaaatac atccactcca ccaagaacgt
    29701 tatacaccgg agaatcagtg actctgattt tttgcaactt ccctgtcaga agataattat
    29761 agaatgacag ttgagaagaa aatacctttc cgttctcctc atacatacca agaagtttac
    29821 aggtaaattt atcaagagcg ccagagaatg tattaatcat ttcattcatt ctcttcacat
    29881 gaatgttaat atcatctttc ttttctttaa tacttttttt gcgtttttcc agtttttcta
    29941 cacgcccatc tggtctgtag atcagcgtaa agtaaagagt gttccccttg aatttatttt
    30001 tcttcatcga accatagtaa caatctgata ttatatcagc atatttatta cctgattttg
    30061 tggtaaaggc atcataaaaa ctcgccctgc atgaatggtt ataaaatgaa acgggcagtc
    30121 cggaaaatga acgaacaaga gtggcaacct gtgagtcaat agtttctaac atctccgcag
    30181 agattgactc aaagttaatc cccatcagtt gccatgtcgc tacataatca ccgttctttg
    30241 ttttgacaat atttttatca acatggcttg aatagggtat atatttacca gtagtgattc
    30301 gctcattcag tttcatggca ttaacaaact catcaatttc aacagcttca tattgtccgg
    30361 agaggaacgc tcgtgcgcca aaaaaacgat tacacactga gtttccgagc attttcagct
    30421 taagaaagta aaggttaaaa atgtggtcgt cctgtttagt gatcattctg agaacaaaaa
    30481 ccgcgacagg aatagccagc cagatcagct tgctgatata aacccccgcc agaaataacg
    30541 cccctgcaac cacagtaaga gggacgacag gaacacccac atacatagca gggcgtgtca
    30601 tcgctttata aagtgtagac atactatcgt ccccgcttta ttagttaacc atcattgatg
    30661 caacttcagc cgcactggcg ataacaattg ccccgatgat gataggtgag cattcacgaa
    30721 tcgtgcttcc accaaacaga accttgtagc cgacccacag acaggcaata gtcaccgtga
    30781 ccagtgaaag gccactaagc cctgttttaa ccttttccag cagtgtttcc gcttttgaaa
    30841 atccatccgc aaaggccggt gatgcaactg ttgccccggc gactgccata actaccttat
    30901 ttttacgctg cattacagca gtgacagatg aactgatacg attacatact gatttcttaa
    30961 atgacatttt ataagtcctg ttaattaata acttttgttg gatgtgagtt atcaacaaaa
    31021 gcagatttca gaatggtttc gggccagata actgacgcat tgtgtgaacg attttttcgc
    31081 tgttctcccc cgttgcttct tgtacctggt acaacatatt ttttttcgtt ccctgtataa
    31141 ccaattcgct caacataact tgtattatta aattcttttt cttttcgctt accgttacta
    31201 aaatttcctg tatagtaaca actaagcgca ttctccaggc tcctccctcg tttataacaa
    31261 tccacgataa tcttttcgaa aacagacaag ttttcacacg aatcaaggag tttttctgcg
    31321 gacgtggaat aaaaagaaaa attactgctg gtaatctgca tcaatccgac agaataacgt
    31381 ctttttctgt tttcaatttc tctgataact gttagagctt cctccttact tttgggcata
    31441 tgactgataa cacttttgcc atagctaccg cgttcccttt caggaataat ttcagccaca
    31501 gcataaggat tgaagccact ctcgacccgt gcaatatcat ttatcgtatc cggatgaact
    31561 gacgccgcac acagcaacaa ggctgggaat aaagacgcca tagctaacgc tccatatatc
    31621 catcaatacg catactctgc attaataagt aaataatttg cttcctctta ctaagcaaag
    31681 atgttttcgt tttctcttcg ataaatgcat tcaacctggg atcgagtttt atcgtgacat
    31741 aaaccccttt ttccgatgac ttatctgatt tctccttcat ttaatcaatc cactataagt
    31801 gtgttttgga tttgttttag atgcgaacat gattcgcaaa ataacaatgc tcaacaatac
    31861 gatcaaataa cattgacaaa atggtcatat tatgattcgt gtgatcatgc aaaaaaaagc
    31921 gcccatatgg gcgctctagt atgattgaaa cattagttaa tcgaatgtag ggactggagc
    31981 atccttctga gactgaataa acaatgcttg tttaacattc ttacagttct gagaatcaga
    32041 gccagacttc tcacactctg cctgcttttg tttagcttcc gtaagatgct gcccccacca
    32101 atccacactt tttacttctt cactacaacc aacaacgaag aacggcaaag caaaaagcag
    32161 atattttttc ataaattccc cctctcactg atcctggaaa gacttgacac gagaagggca
    32221 ttagtccgaa tgagtaccag tgttctgatc cctgccaacg agacacctcc cagttcagct
    32281 cttacagaat cgagatattt tctgacagtt gaaggcttta gtcctttgaa atcagcaatt
    32341 tcattcaggg tatagccata agcgtacatc agaataatgt ctttttgttg ctcactcaaa
    32401 tgttcttcat cactaaaaat ttgatgaagt ccagaaatgc agatagcatc atgctcagtc
    32461 atgataacct ccctcgtagg ttgttgtgat cagcaggtga gcaaagtagc cgctttgttc
    32521 acctgcgcca aaatcaaatt aaaatcccag gcctttccag ttcctctctt gctgtattct
    32581 tagtttttta tgttcttctg aatcctttgt aaacccgtgt tcaagagcaa acccgatatt
    32641 gtgaccttgc tcatgttttc tggatagctg ctttttaacg tcgctctctt ccggctgcct
    32701 ggtttcacgc tcatgaacct gacgttctct gttccgctca agggcaatat tttcaatctg
    32761 ccagttattg cgatgcgttt ccctgtagcc tgcaacagtt ccatcatcat taaacattgg
    32821 actacgtaca agcgtaggag ccagtttttt tactttgata agcgttcctg gctggagctt
    32881 ttcagactcg aaatgatttt tcaggtcttt accccaaatc gtaacctgtt ttccaccttt
    32941 taaagtttca taagtgagga aaggtgttcg tttttcccct gccttattct gatatgaagt
    33001 ctccccaaaa tccaccacct tgtaaacatt ccggagtctt ttcggatttt cagcctgtaa
    33061 tcgctcaatc tcccgtttac gttcgggatc ttttttccag gtagcggtaa catcatatcc
    33121 catacctttc agttttctat gaaaaccgtt tctgaacttc ctggtttcag atttagtaag
    33181 tcttaatctt cttcctgttt cttcatcacg aagtttaata ttaacatgta catgaggatg
    33241 atcttcttta tcatcatggt atacggcaac gaaagcatgg tttggataag tctctttaag
    33301 aaattctacc
//
