LOCUS       NZ_CP061129             7395 bp    DNA     circular CON 09-DEC-2023
DEFINITION  Salmonella enterica subsp. enterica serovar Typhimurium strain S304
            plasmid pS304_3, complete sequence.
ACCESSION   NZ_CP061129
VERSION     NZ_CP061129.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN15962523
            Assembly: GCF_015697825.1
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica subsp. enterica serovar Typhimurium (Salmonella
            typhimurium)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhimurium
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 7395)
  AUTHORS   Hua,X. and Yu,Y.
  TITLE     Plasmid dynamics of mcr-1-positive Salmonella spp. in a general
            hospital in China
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7395)
  AUTHORS   Hua,X. and Yu,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-SEP-2020) Sir Run Run Shaw Hospital, Zhejiang
            University, Qingchundong 3 RD, Hangzhou, Zhejiang 310016, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 01-JUN-2020
            Assembly Method                   :: other: Unicycler v. 0.4.8
            Assembly Name                     :: S304
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 12/09/2023 11:57:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,200
            CDSs (total)                      :: 5,077
            Genes (coding)                    :: 4,934
            CDSs (with protein)               :: 4,934
            Genes (RNA)                       :: 123
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 15
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 41 of 143
            Pseudo Genes (incomplete)         :: 115 of 143
            Pseudo Genes (internal stop)      :: 21 of 143
            Pseudo Genes (multiple problems)  :: 31 of 143
            Pseudo Genes (short protein)      :: 1 of 143
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP061129.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..7395
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhimurium"
                     /mol_type="genomic DNA"
                     /strain="S304"
                     /serovar="Typhimurium"
                     /isolation_source="stool"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90371"
                     /plasmid="pS304_3"
                     /geo_loc_name="China:Hangzhou"
                     /lat_lon="30.2 N 120.2 E"
                     /collection_date="2015-05"
                     /collected_by="Xiaoting Hua"
     gene            complement(join(6580..7395,1..1668))
                     /locus_tag="IBY93_RS26115"
     CDS             complement(join(6580..7395,1..1668))
                     /locus_tag="IBY93_RS26115"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA transfer
                     family protein"
                     /protein_id="WP_025769090.1"
                     /translation="MKKNIQAGIFFVTMLLPVWHAAAETFTRCHPNETVWAMIQDEQLK
                     NIARLQETKRCQAVNDTYDQWRQNFQAMGDAENAIRSARDNQNWNAVKSTFDNIAPQIN
                     SLHALAEKNSSLLGAGNILALFGGDLNYLYQNAGLVAPASADGLTDNVSQMLTEPDKQV
                     KAAGIAQQLVYQTRVRAQSFIQGVAQNAGNEAQKEYREQSDKIVEDKAHNFKGDSVEGY
                     FGGFLARISQVYAPVLLFLIIVGIIGALTARRVRLDAFTASVKAVMAAVVPAVALALML
                     IFMPFLPSWVLYTAALAGTFAIYSRSKQILGGLASRCGRFPTLASGLRWMGGFVSGIDA
                     DRKQETGAASVNPASHHTHGSSRWGTAAEMRENNHLLPTEKQAGFTLARELSPPPGVDG
                     KFCFTGHVVTVAPTGSGKGIGAVIPNLLTYQGSALVFDPKGENAEVTGRRRREMGQSVH
                     VIDPFGITSGIKESVNILDRLDVTSPDCVAESAVLAESLVVSEKGGDSNHFDESARTLL
                     QGLMLHVSGLPDESRRNLAELRRLITSDEENLLALLADMAASEDVAFGIPARAANTLMG
                     MADRERGSVLSTARKNTAFLDDPRIAAALSHSDFNLSAIKAEPMTVYLVLPANRIAANT
                     RFIRLFIGSVISAVTESKAKPAHNVAFILDEFNVLGYMKSIEDAVSLLRGYGLSFWVFL
                     QDLSQLKSAYPKWQTFLANSAKTFYGTDDYDTAKYVSDTLGKSTVEFETQNSGRNSGSG
                     VSGGGGSMNRGRSSGSSQQFAGRELLTPDEVMRLGPTRPIVILKGEYPYQLTRINYLTD
                     PEYAGMADPNPYYSA"
                     /name="type IV secretory system conjugative DNA transfer
                     family protein"
     gene            complement(1716..2018)
                     /locus_tag="IBY93_RS25745"
                     /old_locus_tag="IBY93_25730"
     CDS             complement(1716..2018)
                     /locus_tag="IBY93_RS25745"
                     /old_locus_tag="IBY93_25730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008451932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_023139325.1"
                     /translation="MAKSRAEKLEELRQKEAQIKAQIQQLKQREQTEERKKDTRRKILI
                     GGAVLAKIKRGEWNYHQLVSLLDNELKNDRDRALFDEMGLKAVDARKESFNPGNK"
                     /name="hypothetical protein"
     gene            2178..4001
                     /gene="mobQ"
                     /locus_tag="IBY93_RS25750"
                     /old_locus_tag="IBY93_25735"
     CDS             2178..4001
                     /gene="mobQ"
                     /locus_tag="IBY93_RS25750"
                     /old_locus_tag="IBY93_25735"
                     /inference="COORDINATES: protein motif:HMM:NF015354.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobQ family relaxase"
                     /protein_id="WP_023139326.1"
                     /translation="MAIFHLSVKTISRSAGRSATAAIAYRTGSRIVDERTGITHDYTRK
                     SGVEHSEIFLPQNSPGWASNRETLWNAVEQKENRRNSTVAREFELAFPAELDGKQRLDL
                     LREFCSSLVERHGMAVDAAIHAPGKEGDQRNYHAHVLCSTRRLSEEGFKDKTRELDDFK
                     SGEVNYWRSAWSEMTNRHLEKAGRSERIDHRSLEAQRESAISQGDSAKAAELDRVPTIH
                     IGYAAAQMEKRGIETERGNEHRQIILRNAEIQPLSRAIQLIENWRATHDNNSRAGHGSI
                     APVPARDTGRDRRGVRTAQSNTGRAGAVPPPSARGRLRNLSELDMVRFGERSEMLLPGN
                     VSRDVEHQRTDRNQPLRRENTVTSKPKRPEIIRLEWQRLRRDKLTFVHDKAGRIAARGA
                     AQVERQRQKISSHERQRPEQPSGLIGMFKRSAYEQAASTWQTIKNGLDRRLVQLKNRLG
                     FVRGYMRKSGAYEMSTPGERLADQLAAKENPILAGQIKSLNAQKNAEDMAAYRTRVQSR
                     KQEKADMKLETIEELKQRGDARRDKADKAERAELEKASHQASLQNETIGEETKELESGE
                     KEKLSKRDQVLEKFKAKFERDKQNERGGRGR"
                     /name="mobQ"
     gene            4144..4563
                     /locus_tag="IBY93_RS25755"
                     /old_locus_tag="IBY93_25740"
     CDS             4144..4563
                     /locus_tag="IBY93_RS25755"
                     /old_locus_tag="IBY93_25740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000063058.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HigA family addiction module antitoxin"
                     /protein_id="WP_113398076.1"
                     /translation="MSEEQRRRGFMKAEASLRLEGIDPSGIPRYESIKARVISGEITYE
                     QGRAEILAFHTGKCAEPTTAGEMLAEEFLKPLNMSQGELAQATGIPEHHIDDIISNRRR
                     LSAEEPYKLAEQFQTDKDFWLNLQALHDAWLTHQK"
                     /name="HigA family addiction module antitoxin"
     gene            complement(4724..5077)
                     /locus_tag="IBY93_RS26120"
     CDS             complement(4724..5077)
                     /locus_tag="IBY93_RS26120"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_227664254.1"
                     /translation="MITQLKGRKIALVSFCWYELICTQMNGNQFSQEKKVKGSKPSIWS
                     ITEGEVIMATINLSLLEHDCGEAAREALLSGVPVYYADETTPENCVIKEYPDGRRELVS
                     FMTGMEKLVGANT"
                     /name="hypothetical protein"
     gene            complement(5466..5606)
                     /locus_tag="IBY93_RS25765"
                     /old_locus_tag="IBY93_25750"
     CDS             complement(5466..5606)
                     /locus_tag="IBY93_RS25765"
                     /old_locus_tag="IBY93_25750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_071994383.1"
                     /translation="MQEPPVQPDCCAFPGNYRLESNPGRHDKAPLAAAIGNWKFAENLF
                     S"
                     /name="replication initiation protein"
     gene            5965..6327
                     /locus_tag="IBY93_RS25770"
                     /old_locus_tag="IBY93_25755"
     CDS             5965..6327
                     /locus_tag="IBY93_RS25770"
                     /old_locus_tag="IBY93_25755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019105480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="entry exclusion protein 1"
                     /protein_id="WP_113398075.1"
                     /translation="MAWHSVSQAQNMTGKSRRTLYRDMASGRLSWRTNASGHRELETSE
                     LIRVYGEIKKDGTAERHIVAQPDDTVPSRVMMDELRALRQEVSDLKSMLLRLEHKPEKP
                     PEVAAPWWRFWQKKST"
                     /name="entry exclusion protein 1"
     Typing          complement(5498..5865)
                     /name="rep_cluster_2370"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="90.566"
                     /coverage="85.0"
                     /evalue="8.49e-135"
ORIGIN
        1 catatcggcc agcagggcta acaggttttc ttcatcactg gtgatcagtc gacgtagttc
       61 cgcgagatta cgtcgggact catccggtaa tccggaaaca tgcagcatca ggccctgtaa
      121 cagggtccgg gctgattcat caaaatgatt actgtcacca cctttctctg ataccacaag
      181 gctttcggcc agaactgcag attcagcgac gcaatccggg ctggtcacat cgagacgatc
      241 cagaatgttc actgattctt ttatgccgct ggttatgccg aatgggtcaa ttacgtggac
      301 gctctgaccc atttcacgac ggcggcgacc tgtcacctcg gcgttttccc cttttggatc
      361 aaagacaagc gctgaacctt gataagtcag aagattggga attactgcgc caatcccttt
      421 tccgctgccc gtaggggcaa cagtcacaac gtgcccggtg aaacagaatt ttccatccac
      481 tccgggcggt ggggacagtt ctcgtgccag ggtgaatccg gcttgctttt ccgttggtaa
      541 caggtggtta ttttcccgca tttctgcagc ggttccccag cgtgatgagc cgtgagtgtg
      601 atgtgaggcc gggttgacgg atgccgcgcc cgtttcctgc tttctgtcag catcgatgcc
      661 agacacaaaa ccgcccatcc agcgaagccc ggaggccagt gtggggaaac gcccacagcg
      721 agaggccagc cctccaagaa tttgtttact gcgggaataa atggcgaatg ttccggccag
      781 cgctgccgtg tacaataccc atgatggtag gaaaggcatg aatatcagca tcagcgccag
      841 tgctactgca ggtaccactg cggccataac tgctttcact gatgccgtga aagcatccag
      901 ccttacccgc cgtgcggtaa gtgcaccaat aataccaacg atgataagga acagcagaac
      961 tggagcatat acctggctta tccgggcaag aaagccgccg aaatatcctt ccacgctgtc
     1021 acctttaaaa ttatgggctt tatcctcgac aatcttatct gattgctcac gatactcttt
     1081 ctgggcttcg ttaccggcgt tctgtgccac gccttggata aaactctgtg cccgaacccg
     1141 agtctgataa accagctgtt gcgcgatacc tgcagctttg acctgtttat ccggttcagt
     1201 cagcatttga ctgacgttat ctgtcagtcc gtcagcgctg gccggggcaa cgagccctgc
     1261 attctggtac aggtaattca gatcgccgcc gaaaagcgcc aggatgttac ccgcgcccaa
     1321 taacgatgaa tttttttctg ccagtgcatg caggctatta atctggggag caatgttatc
     1381 gaacgtggat tttacggcgt tccagttctg attatcgcgg gcgctgcgga tggcgttttc
     1441 tgcatctccc atcgcctgga aattttggcg ccactggtca taagtgtcat taacggcctg
     1501 acaccgcttt gtttcctgta gtctggcgat gttttttagc tgctcatcct ggatcattgc
     1561 ccagacagtc tcatttggat ggcagcgggt gaatgtttcg gccgctgcat gccatactgg
     1621 caatagcatt gtgacgaaga aaatcccggc ctgtatattt tttttcatgc taaatctcct
     1681 gatctgattc atcatccgag aataagtaat tggcgtcact tattaccggg gttaaaagat
     1741 tcttttctgg cgtcaaccgc ctttaaaccc atttcatcaa atagtgcccg gtctctgtca
     1801 tttttcagct cattgtccag aagactcacc agctgatgat aattccattc cccacgcttt
     1861 atttttgcga gtacggcacc accgattagg atttttcgtc gggtatcctt cttgcgttct
     1921 tctgtctgct ctctttgctt taattgctga atttgcgcct ttatctgagc ttctttctga
     1981 cgcaactctt ccaacttttc cgctcttgat tttgccatta ttcacctctt tgattcaaat
     2041 ttgaacgata actccattgc tgatatattt caacccgaag cgaaagcaaa gggcgcactt
     2101 atgcaaactc ttcgagtttg cgtgcggcag ggttaaaacc ctgcacccaa ggtcaaagga
     2161 aaaacaggaa tactaaattg gcaatttttc atcttagcgt taagacaata agccgtagtg
     2221 ctggccgttc ggccactgcg gcaattgctt atcgtacagg ttcaagaatt gttgatgagc
     2281 gaactgggat tacccacgac tacacccgta aatcaggcgt cgagcattca gagatttttc
     2341 tccctcaaaa ctcaccaggt tgggcgagta atcgggagac tctctggaat gcagttgaac
     2401 agaaagaaaa ccgtcgtaat tcaaccgttg ccagagaatt tgaactcgca tttcctgccg
     2461 agcttgacgg aaaacagcgt ctcgatctgc ttcgtgagtt ttgttcttca ctggttgagc
     2521 gtcacggaat ggcagtggat gccgctatcc atgctccggg taaagagggt gaccagcgta
     2581 attatcatgc tcatgtttta tgcagtaccc gccgactgtc ggaggaaggt ttcaaggata
     2641 agacccgtga acttgatgat tttaagagcg gcgaagtcaa ctactggcgt tctgcatggt
     2701 cagaaatgac gaaccgtcat ctggaaaaag ctggccgttc agagcgtatt gaccatcgtt
     2761 cacttgaggc gcaacgggaa tcagctattt ctcaggggga ttccgccaag gcagcggagc
     2821 tggatcgggt tccgactatt catatcggtt acgcagctgc gcagatggaa aagcgcggca
     2881 tagagaccga acgaggcaat gaacatcgcc agataatatt gcgtaatgct gaaatccagc
     2941 cgctttcacg ggcaattcag ctgattgaaa actggagggc aacccatgac aacaacagca
     3001 gagcaggaca tggaagcatt gctccagtcc ctgcacgaga cacagggcga gataggagag
     3061 gagtccgcac cgctcagtcc aacactggcc gcgctggagc cgtcccgccg cccagcgcaa
     3121 ggggtcgcct gcgcaacctg tccgaactcg atatggttcg cttcggagaa cgaagtgaga
     3181 tgttattgcc gggcaatgta tctcgtgacg tggagcacca gagaaccgac agaaatcagc
     3241 ctctgcgacg ggaaaacact gtaaccagca agccaaagcg accggaaatt atccggcttg
     3301 aatggcaacg tttacgccgg gataagctga ctttcgttca cgataaggcc ggacggattg
     3361 ccgcccgtgg ggcggcacag gttgaacgcc agagacaaaa aatatcctca catgagcgac
     3421 aaagaccaga acagcccagc ggcctgatag gaatgtttaa gcgcagcgcc tatgaacagg
     3481 ccgccagtac ctggcagacc atcaaaaatg gtctcgatcg tcgtctggtg caactgaaaa
     3541 atcggcttgg ctttgtcaga ggctacatgc gcaagtctgg cgcttacgaa atgtctacgc
     3601 cgggagaacg gctggccgac cagctggccg cgaaagaaaa tccgatcctg gctgggcaga
     3661 taaaatcgct caatgctcag aagaacgcgg aagatatggc cgcataccgt acccgcgtac
     3721 agtcccgcaa acaggagaaa gctgatatga agctggaaac tatcgaagaa ctcaaacagc
     3781 gtggtgatgc ccggagagat aaagccgaca aagccgaacg tgcagagctg gaaaaagcgt
     3841 ctcatcaggc ttcactgcag aatgaaacga tcggcgaaga gacaaaagaa ctggagtccg
     3901 gagagaaaga gaaactcagc aagcgtgatc aggttctgga gaagtttaaa gcaaaattcg
     3961 agagggataa gcagaatgaa cgtggtggcc gtgggcgtta gcggtatgca acacagcgcc
     4021 aaccatgctg catacctgac ccggccagac tgatcaggcg tcttttcggg ctgaaagcat
     4081 tgtactggtt aacagtattt catgacatat gaggtacgcc tgatattgac atatgaggta
     4141 gatatgagtg aagaacagcg caggcgtggc ttcatgaagg ctgaggcaag cctgagactg
     4201 gaaggtatag atcccagcgg aatcccccgc tacgagtcga ttaaagcgag agttatttcg
     4261 ggtgagataa cctatgagca gggacgagct gaaattctgg ctttccatac cgggaagtgt
     4321 gcggagccga caactgcggg ggaaatgctc gcagaggaat ttttaaaacc tctgaacatg
     4381 tctcaggggg aactggcgca ggctacagga attcctgagc atcatatcga tgatattatc
     4441 agtaaccgcc gtcgcctcag tgctgaggag ccttacaagc tggccgaaca gttccagacc
     4501 gataaagatt tctggctcaa cctgcaggct ttgcatgacg catggctgac gcaccagaaa
     4561 tagcagccag gggcgcgatt agatatataa tgttccagtc taatgtagga tgttccatgc
     4621 aggtcagagt attaaaaata aagccccgtc cttaccaggc ggggctttat tttttcctgc
     4681 ccctcaagtg tcataatggt tctgaaatcc ggacatccaa aaatcatgta ttagccccaa
     4741 cgagtttctc cataccagtc atgaagctca ccagttccct gcggccatcc ggatattctt
     4801 tgataacgca gttttctggt gtcgtctcat cggcgtaata gacaggaacg ccgctgagaa
     4861 gagcttcgcg ggcggcttcg ccgcagtcat gttccagtag tgatagatta atggtcgcca
     4921 tgatgacttc tccttcggta atactccaaa tggatggttt tgaccctttg accttctttt
     4981 cctggctaaa ttgattgcca ttcatttgtg tgcatatcaa ttcataccaa caaaaactca
     5041 ccagtgcgat tttacggcct tttaattggg taatcatggt cttttgaggc ttagggcata
     5101 aaaacgcgct gagggcctct gaggcggttc tgctaacgga tgttatggta aatgcgagtg
     5161 accggcatgg tgactcttaa tttatttttc gacttctccc ccccctcctt gcccctacaa
     5221 ccccatggag cccatgccac ttgtcaactt cacgggtttg tcatgatctt cttgagattc
     5281 tttgtttatc gtcgtagtct cttgtcctgt aaacgaaaaa accacccggc aaggtggttt
     5341 ttcgaaggtt cagtaaaccg gcaagtttct gaaccgtggt aactggctta cgcagagcac
     5401 agcaaccaaa tctgtccttc cagtgtagcc gtactttggc gcacacttca agagcaaccg
     5461 cgtgtttagc taaacaaatt ctctgcgaac ttccagttac caatggctgc tgccagtggc
     5521 gctttgtcgt gtcttcccgg gttggactca agacgatagt taccgggaaa ggcgcagcag
     5581 tcgggctgaa cggggggttc ttgcatacag cccagcttgg agcgaacgac ctacatcgag
     5641 ctgagatacc tacagtgtga gctatgagaa agcgccacat gtcccgtaag ggaaaaaggc
     5701 ggtcaggtat ccggtaaagc gacacggtcg gaacaggaga gcgcaagagg gagcgattca
     5761 ccggaaacgg tgatgatctt tatagtcctg tcaggtttcg ccgcctctgg cttgagcgtc
     5821 tgtttttgtg atgctcgcca ggggggcgga gcctatggaa aaacgggtct gccgcttttt
     5881 tttccccttc ttgccgcgtg tcaggatgcc gttagcctgc tagagtgcag cccgtagagt
     5941 gtgtcactta atcaaggggg tgttatggca tggcacagtg tgtcacaagc acaaaacatg
     6001 acagggaaaa gtcgcagaac cctttatcgg gatatggcgt ctggccgctt gtcatggcga
     6061 actaatgcta gcggccatcg cgaacttgag acctcagagc tgatccgtgt ttatggcgag
     6121 attaaaaaag atggcacagc tgaacggcac atcgtggcac agcctgatga caccgtgccc
     6181 agtagggtca tgatggatga attgcgtgct ttacggcagg aagtttctga ccttaaatct
     6241 atgctgttaa ggcttgagca taaaccggaa aagccgcctg aagtagcggc tccgtggtgg
     6301 cgtttctggc agaaaaaatc tacttaactc ttttctcttt ttcgcggcta aagttgatta
     6361 cgttatccgg tagagtttca ggctttgtgg tcttttgtgt ctctattgtc atagcactac
     6421 gtcttctgtt ttgcgtcacc agagcccaga taaaggcaca gataaagcgg aaagagaagt
     6481 atatcggtat gcctatcaca aaggcgacgg cggttaaggc cgggagcaag acccggccaa
     6541 acatcagagc taacagtacg ccgacaacga ttccaaatat catgcgctgt agtaggggtt
     6601 aggatctgcc ataccggcgt attctgggtc tgtcagatag ttaatacggg tgagctgata
     6661 agggtattcc cctttcagaa tcacaattgg tcgggttggt ccaagcctca tgacttcgtc
     6721 aggtgtcagt aattccctcc cagcaaactg ctgacttgat ccagacgaac gaccccgatt
     6781 catggagccg ccacccccgg aaacaccgct gccagagttg cggcctgaat tctgggtttc
     6841 aaattcaacc gtcgatttac ctagggtgtc gctgacgtat tttgcagtgt catagtcgtc
     6901 tgtgccgtag aacgtcttcg ctgagttggc cagaaacgtc tgccatttag ggtaagcact
     6961 tttcagctgt gacagatcct gcaggaatac ccagaaagac agcccgtatc cgcgtaacag
     7021 gcttacggca tcctcgattg atttcatata ccccagcacg ttgaactcat cgaggatgaa
     7081 tgcgacatta tgagctggct tcgccttcga ttctgttaca gcggagatca cagaaccgat
     7141 aaacagcctt ataaatcggg tatttgctgc aatgcgatta gctggtagca cgagataaac
     7201 tgtcatcggt tcagctttga tggctgacag gttgaagtct gagtgtgaca gcgcagctgc
     7261 tatacgcggg tcgtccagaa atgctgtgtt tttacgggcg gtagacaata ctgagcctcg
     7321 ttcccggtct gccatcccca tgagcgtgtt ggccgctcgg gcggggatac cgaaagcaac
     7381 gtcttcactt gcggc
//
