LOCUS       NZ_CP060927            24892 bp    DNA     circular CON 24-MAY-2024
DEFINITION  Escherichia coli strain EC14 plasmid pEC14-4, complete sequence.
ACCESSION   NZ_CP060927
VERSION     NZ_CP060927.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN15904658
            Assembly: GCF_022558805.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24892)
  AUTHORS   Ruan,Z.
  TITLE     Complete genome sequence of carbapenem resistant Escherichia coli
            isolates
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 24892)
  AUTHORS   Ruan,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-AUG-2020) Department of Clinical laboratory, Sir Run
            Run Shaw Hospital, School of Medicine, Zhejiang University, 3
            Qingchun East Road, Hangzhou, Zhejiang 310016, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022558805.1-RS_2024_05_24
            Annotation Date                   :: 05/24/2024 04:04:27
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,053
            CDSs (total)                      :: 4,935
            Genes (coding)                    :: 4,686
            CDSs (with protein)               :: 4,686
            Genes (RNA)                       :: 118
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 249
            CDSs (without protein)            :: 249
            Pseudo Genes (ambiguous residues) :: 0 of 249
            Pseudo Genes (frameshifted)       :: 69 of 249
            Pseudo Genes (incomplete)         :: 188 of 249
            Pseudo Genes (internal stop)      :: 34 of 249
            Pseudo Genes (multiple problems)  :: 40 of 249
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP060927.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..24892
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="EC14"
                     /isolation_source="wound"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="pEC14-4"
                     /geo_loc_name="China: Hangzhou"
                     /collection_date="2016-11-16"
                     /collected_by="Long Sun"
     gene            complement(join(24721..24892,1..>2))
                     /locus_tag="H9201_RS24990"
                     /old_locus_tag="H9201_24720"
                     /pseudo=""
     CDS             complement(join(24721..24892,1..>2))
                     /locus_tag="H9201_RS24990"
                     /old_locus_tag="H9201_24720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005220836.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /name="Tn3 family transposase"
     gene            40..600
                     /locus_tag="H9201_RS24995"
                     /old_locus_tag="H9201_24725"
     CDS             40..600
                     /locus_tag="H9201_RS24995"
                     /old_locus_tag="H9201_24725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000147566.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000147567.1"
                     /translation="MTGQRIGYIRVSTFDQNPERQLEGVKVDRAFSDKASGKDVKRPQL
                     EALISFARTGDTVVVHSMDRLARNLDDLRRIVQTLTQRGVHIEFVKEHLSFTGEDSPMA
                     NLMLSVMGAFAEFERALIRERQREGIALAKQRGAYRGRKKSLSSERIAELRQRVEAGEQ
                     KTKLAREFGISRETLYQYLRTDQ"
                     /name="recombinase family protein"
     gene            603..3554
                     /locus_tag="H9201_RS25000"
                     /old_locus_tag="H9201_24730"
     CDS             603..3554
                     /locus_tag="H9201_RS25000"
                     /old_locus_tag="H9201_24730"
                     /function="required for transposition of transposon Tn21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138064.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element TnAs3 family transposase"
                     /protein_id="WP_015344976.1"
                     /translation="MPRRSILSAAERESLLALPDSKDDLIRHYTFNDTDLSIIRQRRGP
                     ANRLGFAVQLCYLRFPGVILGVDELPFPPLLKLVADQLKVGVESWNEYGQREQTRREHL
                     SELQTVFGFRPFTMSHYRQAVQMLTELAMQTDKGIVLASALIGHLRRQSVILPALNAVE
                     RASAEAITRANRRIYDALAEPLADAHRRRLDDLLKRRDNGKTTWLAWLRQSPAKPNSRH
                     MLEHIERLKAWQALDLPTGIERLVHQNRLLKIAREGGQMTPADLAKFEPQRRYATLVAL
                     ATVTDEIIDLHDRILGKLFNAAKNKHQQQFQASGKAINAKVRLYGRIGQALIDAKQSGR
                     DAFAAIEAVMSWDSFAESVTEAQKLAQPDDFDFLHRIGESYATLRRYAPEFLAVLKLRA
                     APAAKNVLDAIEVLRGMNTDNARKLPADAPTGFIKPRWQKLVMTDAGIDRRYYELCALS
                     ELKNSLRSGDIWVQGSRQFKDFEDYLVPPEKFTSLKQSSELPLAVATDCEQYLHERLTL
                     LEAQLATVNRMAAANDLPDAIITESGLKITPLDAAVPDTAQALIDQTAMVLPHVKITEL
                     LLEVDEWTGFTRHFTHLKSGDLAKDKNLLLTTILADAINLGLTKMAESCPGTTYAKLAW
                     LQAWHTRDETYSTALAELVNAQFRHPFAGHWGDGTTSSSDGQNFRTASKAKSTGHINPK
                     YGSSPGRTFYTHISDQYAPFHTKVVNVGLRDSTYVLDGLLYHESDLRIEEHYTDTAGFT
                     DHVFALMHLLGFRFAPRIRDLGDTKLYIPKGDAAYDALKPMIGGTLNIKHVRAHWDEIL
                     RLATSIKQGTVTASLMLRKLGSYPRQNGLAVALRELGRIERTLFILDWLQSVELRRRVH
                     AGLNKGEARNALARAVFFNRLGEIRDRSFEQQRYRASGLNLVTAAIVLWNTVYLERAAH
                     ALRGNGHAVDDSLLQYLSPLGWEHINLTGDYLWRSSAKIGAGKFRPLRPLQPA"
                     /name="Tn3-like element TnAs3 family transposase"
     gene            3488..3964
                     /locus_tag="H9201_RS25005"
                     /old_locus_tag="H9201_24735"
     CDS             3488..3964
                     /locus_tag="H9201_RS25005"
                     /old_locus_tag="H9201_24735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005108951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_223171565.1"
                     /translation="MAQQRQDRRGEVQAATASATGLACFIFRFLRRPLVVCGLAWQGAG
                     IFNLPFTVMLWTIIRLIIVVSLVFITGKFGLSREFTFPAAAVGLAFSLFPVLDHIALGY
                     SAKNFYETTNFMGQTVREFGASKITVWWGSIYAKIAYASLAGLIGYGVKVATDD"
                     /name="hypothetical protein"
     gene            complement(4049..4753)
                     /locus_tag="H9201_RS25010"
                     /old_locus_tag="H9201_24740"
     CDS             complement(4049..4753)
                     /locus_tag="H9201_RS25010"
                     /old_locus_tag="H9201_24740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067784.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1006 family transposase"
                     /protein_id="WP_001067784.1"
                     /translation="MNPFHGRHFQGEIILWAVRWYCKYGISYRELQEMLAERGVNVDHT
                     TIYRWVQRYAPEIEKRLRWYWRNPTDLSSWHIDETYVKVNGRWSYLYRAVDQRGDTIDF
                     YLSSRRNTKSAYCFLGKILNNVKKWQIPQVINTDKAPTYGRALSRLKREGKCPPDLEHR
                     QIKYKNNVIECDHGKLKRIIRATLGFKSMKTAYATIKGIEVMRALRKGQASSFYYGQPQ
                     GEVCLINRVFGL"
                     /name="IS6-like element IS1006 family transposase"
     gene            <4817..5647
                     /locus_tag="H9201_RS25015"
                     /old_locus_tag="H9201_24745"
                     /pseudo=""
     CDS             <4817..5647
                     /locus_tag="H9201_RS25015"
                     /old_locus_tag="H9201_24745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001120888.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS91-like element ISVsa3 family transposase"
                     /name="IS91-like element ISVsa3 family transposase"
     gene            5678..6562
                     /locus_tag="H9201_RS25020"
                     /old_locus_tag="H9201_24750"
     CDS             5678..6562
                     /locus_tag="H9201_RS25020"
                     /old_locus_tag="H9201_24750"
                     /inference="COORDINATES: protein motif:HMM:NF023271.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3363 domain-containing protein"
                     /protein_id="WP_001447541.1"
                     /translation="MLRSQRRGRDPPCWLSEKEPLVGKRRVNFQRCWLPVSRIGLHRRG
                     VERVNCGPKLLDLGEKGVYSSYTCRVPGGDYEGYVDAHVRRLEALRRAGIVERIDADQW
                     RIPDDLVSRAAAHDAGRDSQASVRVLSPVDLNKQIGSDGATWLDRRLIHGETADLAPTG
                     FGQQVREAMDQRREHHIEQGDATRSRDSRVFYRRNLLAILREREVAGVGSDMALSKGLP
                     FRAATDGESVSGKFTGTVHLSSGKFAVVEKSHEFTLVPWRPIIDRQLGREVMGIVQGGS
                     VSWQLGRQRGLER"
                     /name="DUF3363 domain-containing protein"
     gene            6779..7993
                     /gene="floR"
                     /locus_tag="H9201_RS25025"
                     /old_locus_tag="H9201_24755"
     ARG             6780..7990
                     /name="floR"
                     /gene="floR"
                     /gene_name="chloramphenicol/florfenicol efflux MFS
                     transporter FloR"
                     /tool="amrfinderplus"
                     /drug_class="PHENICOL"
                     /identity="99.75"
                     /coverage="100.0"
     gene            8021..8326
                     /locus_tag="H9201_RS25030"
                     /old_locus_tag="H9201_24760"
     CDS             8021..8326
                     /locus_tag="H9201_RS25030"
                     /old_locus_tag="H9201_24760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001255015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_001255015.1"
                     /translation="MRRTNHRNLVNVGILSGRIPLISLVQFIAVAEHLNFRHAAKALGI
                     SQSSVSARVKALEDNLGVLLFERHARGVRLTDAGRHFMERVTAGVDQLDHAVKTAE"
                     /name="LysR family transcriptional regulator"
     gene            8438..>8827
                     /locus_tag="H9201_RS25035"
                     /old_locus_tag="H9201_24765"
                     /pseudo=""
     CDS             8438..>8827
                     /locus_tag="H9201_RS25035"
                     /old_locus_tag="H9201_24765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001120888.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="transposase zinc-binding domain-containing
                     protein"
                     /name="transposase zinc-binding domain-containing protein"
     gene            complement(<8807..9544)
                     /locus_tag="H9201_RS25040"
                     /old_locus_tag="H9201_24770"
                     /pseudo=""
     CDS             complement(<8807..9544)
                     /locus_tag="H9201_RS25040"
                     /old_locus_tag="H9201_24770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001120888.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="transposase zinc-binding domain-containing
                     protein"
                     /name="transposase zinc-binding domain-containing protein"
     gene            complement(9755..9979)
                     /locus_tag="H9201_RS25045"
                     /old_locus_tag="H9201_24775"
     CDS             complement(9755..9979)
                     /locus_tag="H9201_RS25045"
                     /old_locus_tag="H9201_24775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000743213.1"
                     /translation="MKKPNQDDEPFFITEEIAAEMIAGGYEFELPPIPCTIRLRDVLER
                     MTDAELALQPGEIADQERERCRRKPCSTS"
                     /name="hypothetical protein"
     gene            complement(9976..10713)
                     /locus_tag="H9201_RS25050"
                     /old_locus_tag="H9201_24780"
     CDS             complement(9976..10713)
                     /locus_tag="H9201_RS25050"
                     /old_locus_tag="H9201_24780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001370723.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001446887.1"
                     /translation="MRRTKPVAAPMVARVYLRVSTDAQDLERQEAITTAAKAAGYYVAG
                     IYREKASGARADRPELLRMIGDLQPGEVVIAEKIDRISRLPLPEAERLVASIQAKGASL
                     AVPGVVDLSDLAAEAQGVAKIVLEAVQIMLFRLALQMARDDYEDRRERQRQGIELARQA
                     GRYKGRRADPKRRAQVVALRKSGYSINKTAELAGYSAAQVKRIWAEVSQAEAKQHGAFV
                     EDALTEADALAAVGQDERQEERA"
                     /name="recombinase family protein"
     gene            complement(11199..11339)
                     /locus_tag="H9201_RS25055"
                     /old_locus_tag="H9201_24785"
     CDS             complement(11199..11339)
                     /locus_tag="H9201_RS25055"
                     /old_locus_tag="H9201_24785"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001044210.1"
                     /translation="MNKTKGCLIANFATVPRDEQQHQEQKHVEKKQQQIEQRPRRAARI
                     G"
                     /name="hypothetical protein"
     gene            complement(11345..12049)
                     /locus_tag="H9201_RS25060"
                     /old_locus_tag="H9201_24790"
     CDS             complement(11345..12049)
                     /locus_tag="H9201_RS25060"
                     /old_locus_tag="H9201_24790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(12182..12424)
                     /locus_tag="H9201_RS25065"
                     /old_locus_tag="H9201_24795"
     CDS             complement(12182..12424)
                     /locus_tag="H9201_RS25065"
                     /old_locus_tag="H9201_24795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000008708.1"
                     /translation="MSFKPTPEEVKQARIKAGFTQQEAAKRFGFSLSAWQAKETSGKTS
                     RGLAAGTYELLLLLADEHPDYQLVKREKNQNKETK"
                     /name="hypothetical protein"
     gene            complement(12414..12683)
                     /locus_tag="H9201_RS25070"
                     /old_locus_tag="H9201_24800"
     CDS             complement(12414..12683)
                     /locus_tag="H9201_RS25070"
                     /old_locus_tag="H9201_24800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001006718.1"
                     /translation="MNEVLSDRKNKGNVTYRIVVSEDATRLFIELEKLMKVRSKEADKK
                     TTKKVVFHKSFYYEEFCNVKDEIDDPILLQFYTDTIVKVLNHEF"
                     /name="hypothetical protein"
     gene            complement(12692..13240)
                     /locus_tag="H9201_RS25075"
                     /old_locus_tag="H9201_24805"
     CDS             complement(12692..13240)
                     /locus_tag="H9201_RS25075"
                     /old_locus_tag="H9201_24805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001178641.1"
                     /translation="MQNDKFFERYQPVFEIVCRILGNGWRVNLLDDCQYRIKLTSPQYK
                     NYSIHIRMEKGRLVIIGSVDSRSWRSPYHTCTVSPERNPVEIAADIEKKILTDAFENVE
                     KAMEYERQLQKKREQTQILKGMLSRLIRLDSWHGTLTGFKVENGLDGNVSERGGGFEMV
                     IRGLSVDQLIKVAGFIKQL"
                     /name="hypothetical protein"
     gene            complement(13314..13829)
                     /locus_tag="H9201_RS25080"
                     /old_locus_tag="H9201_24810"
     CDS             complement(13314..13829)
                     /locus_tag="H9201_RS25080"
                     /old_locus_tag="H9201_24810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025391.1"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="WP_001025387.1"
                     /translation="MNIQEALNIFGLSGDLTEKDIKAAYRKAALKYHPDRNPLGAELMK
                     AVNAAFDFLMANIDKINQFQSTDENARYNYGEDLEKVLNTLSGLTGIVYEVIGNWVWIS
                     GETITHKETLKEIGCKWAAKKKQWFYRPEEHKSYWNREEHTIEEIRAKYGSTGQRRATG
                     WQQVETRA"
                     /name="J domain-containing protein"
     gene            complement(14179..14460)
                     /locus_tag="H9201_RS25085"
                     /old_locus_tag="H9201_24815"
     CDS             complement(14179..14460)
                     /locus_tag="H9201_RS25085"
                     /old_locus_tag="H9201_24815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001694627.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_000220561.1"
                     /translation="MTYELAFDRRALKEWQKLGHTIREQFKKKLAERLENPRVPAARLH
                     GHADRYKIKLRASGYRLVYQVIDEKVVLLVIAVGRRESSEVYQIADMR"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(14450..14701)
                     /locus_tag="H9201_RS25090"
                     /old_locus_tag="H9201_24820"
     CDS             complement(14450..14701)
                     /locus_tag="H9201_RS25090"
                     /old_locus_tag="H9201_24820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000121741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="WP_000121743.1"
                     /translation="MSYQILTTTAASITDLKKNPMGTVAEGEGDAVAILNRNEPAFYCV
                     PPKLYAYYRELAEDAELNAVADERMKNPEIVKVNLDDL"
                     /name="plasmid stabilization protein"
     gene            15936..16775
                     /locus_tag="H9201_RS25095"
                     /old_locus_tag="H9201_24825"
     CDS             15936..16775
                     /locus_tag="H9201_RS25095"
                     /old_locus_tag="H9201_24825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001722379.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_001352874.1"
                     /translation="MNLLSVTKKTKIRHRNEINSTFSSLPLSARRILFMAMAQIDSREE
                     LSEGATFRITAREYAFIADIDVTGAYRQLKEGAEELQASVIRIPRNQLLTAQGNQSSGH
                     TKKRGKLPSDAVRLMNLTAFCDYVESEGYIDIAFSHVIEPYITMLKDSYTTQVLISSVR
                     LADQNSNMLYQFIRKQYSSGKKTFFDIEVDVLKDELELFRIDNGEKVYLYQNFKDFNKV
                     FLQKNIEKINQYTEINHLEVKIVERVARRASKLRFSYKIDKESEGLDTRIPYGFRGA"
                     /name="replication initiation protein"
     gene            16796..17638
                     /locus_tag="H9201_RS25100"
                     /old_locus_tag="H9201_24830"
     CDS             16796..17638
                     /locus_tag="H9201_RS25100"
                     /old_locus_tag="H9201_24830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435061.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000435064.1"
                     /translation="MEQIKLHKQGGAAVIIIPASMIENTGWEDGTLLEVLEINETLHIR
                     RKTESGALATKACPSLFSSTMRHVNYDKIIRYNSGLNLLVNELSFSARRVFFICLYYYF
                     ENKLESDKSLLIRADKYAEFVGVERSVAYKQMKDAADFFSRNKNLITHCDYISNEGLLR
                     VMFSSKTINYITAIDSRKYQVTELPLKSALSLQGRYSWPLYQLIKFSHLKSFTIGVDEL
                     KKEIGYIQNQKFSFFKRDGINIAIDEITERTDVKNIKCVNAERQGRRVSKVRFEIEMR"
                     /name="replication initiation protein"
     gene            17642..18088
                     /locus_tag="H9201_RS25105"
                     /old_locus_tag="H9201_24835"
     CDS             17642..18088
                     /locus_tag="H9201_RS25105"
                     /old_locus_tag="H9201_24835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001074384.1"
                     /translation="MAKIYQFPQGEERAKFRKEIARERKKRFAVKTGSTFVKWLGWGWF
                     YLRLLAASVLHFIFVFVLAILGAFKWAVFWLGGILCVITWYHLDHQLWTPQNLTIPVIT
                     ATWILGLLAEPLMELLNKTMPWHKLLVPEPADESTENSSEISQQ"
                     /name="hypothetical protein"
     gene            18225..18581
                     /gene="ddp1"
                     /locus_tag="H9201_RS25110"
                     /old_locus_tag="H9201_24840"
     CDS             18225..18581
                     /gene="ddp1"
                     /locus_tag="H9201_RS25110"
                     /old_locus_tag="H9201_24840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001694624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA distortion polypeptide 3"
                     /protein_id="WP_001714234.1"
                     /translation="MKYQVRKFITDKYAKAVNILKDNLKEHYHVFYGVRLSEILFPAGE
                     YGSEQFFSDFEKINSILLPLLVFDLKTDVPVIVISLDDVSYCDVLNEIDIDFMKCNSLA
                     ELLTSDKLDALFKD"
                     /name="ddp1"
     gene            complement(18602..19462)
                     /locus_tag="H9201_RS25115"
                     /old_locus_tag="H9201_24845"
     CDS             complement(18602..19462)
                     /locus_tag="H9201_RS25115"
                     /old_locus_tag="H9201_24845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001714235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6685 family protein"
                     /protein_id="WP_063122221.1"
                     /translation="MMNIVNTIEFMVKDINKYLDDITLNAITVDGKTILKLEDMSNKNI
                     SPRLEKILRKLIKIEVEHIHNFDFSKLQSLENSKSFEHLPAKSKNPSCYRDLYSWGKGM
                     RHTEKLRAEDESDWKKNIQHIEEEGFRRNRPIEITYYTWLDRYFVSNNGGSHHAALVVW
                     QSVRDKLEYKREANITKLSIDKVSIKKLNSDYWSFILNFRYQTNINTLFNLFNSLVSKH
                     TDMLEPSHYHGNYRLFFVPKSQLKMNKYAFEYWYRNSVKNKKIIALPEYLENPLQFHTG
                     GILIQ"
                     /name="DUF6685 family protein"
     gene            complement(19480..19767)
                     /locus_tag="H9201_RS25120"
                     /old_locus_tag="H9201_24850"
     CDS             complement(19480..19767)
                     /locus_tag="H9201_RS25120"
                     /old_locus_tag="H9201_24850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001722376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcxB family protein"
                     /protein_id="WP_227636918.1"
                     /translation="MKKIMRSNHSSEIKDQELMLRLKINRSYIEQVMKIGSSRVFWNNI
                     KKTYRKQGFLFIQTKENRCIIIPERVFKNEEETEKLYNFVKEKIAQNTME"
                     /name="YcxB family protein"
     gene            complement(19856..20029)
                     /locus_tag="H9201_RS25125"
                     /old_locus_tag="H9201_24855"
     CDS             complement(19856..20029)
                     /locus_tag="H9201_RS25125"
                     /old_locus_tag="H9201_24855"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="WP_215249975.1"
                     /translation="MEKTEASKLIKEHEKQENIEPYGYILLIKKAALLVLSFAALFDFI
                     ILLFDYSSPKSP"
                     /name="aminopeptidase"
     gene            complement(20414..20725)
                     /locus_tag="H9201_RS25130"
                     /old_locus_tag="H9201_24860"
     CDS             complement(20414..20725)
                     /locus_tag="H9201_RS25130"
                     /old_locus_tag="H9201_24860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000358386.1"
                     /translation="MDKKIVDALRTLLEALPEEVITEVTSKLNPSANHIPEENSKQLIA
                     KARVLNFRLTEVYKEILEAEASRTRQSKTTILKAALAAFDSLDENRKNHWLLESAKLG"
                     /name="hypothetical protein"
     gene            complement(20741..20971)
                     /locus_tag="H9201_RS25135"
                     /old_locus_tag="H9201_24865"
     CDS             complement(20741..20971)
                     /locus_tag="H9201_RS25135"
                     /old_locus_tag="H9201_24865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid partition protein ParG"
                     /protein_id="WP_000051066.1"
                     /translation="MSLEKAHTSVKKMTFGENRDLERVVTAPVSSGKIKRVNVNFDEEK
                     HTRFKAACARKGTSITDVVNQLVDNWLKENE"
                     /name="plasmid partition protein ParG"
     gene            complement(21023..21643)
                     /locus_tag="H9201_RS25140"
                     /old_locus_tag="H9201_24870"
     CDS             complement(21023..21643)
                     /locus_tag="H9201_RS25140"
                     /old_locus_tag="H9201_24870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864791.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_001376797.1"
                     /translation="MKVISFLNPKGGSGKTTAVINIATALSRSGYNIAVVDTDPQMSLT
                     NWSKAGKAAFDVFTAASEKDVYGIRKDLADYDFAIVDGAGSLSVITSAAVMVSDLVIIP
                     VTPSPLDFSAAGSVVTVLEAQAYSRKVEARFLITRKIEMATMLNVLKESIKDTGVKAFR
                     TAITQRQVYVKSILDGDSVFESSDGAAKGEIEILTKEIVRIFE"
                     /name="ParA family protein"
     gene            21936..22580
                     /locus_tag="H9201_RS25145"
                     /old_locus_tag="H9201_24875"
     CDS             21936..22580
                     /locus_tag="H9201_RS25145"
                     /old_locus_tag="H9201_24875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001503708.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001376796.1"
                     /translation="MTSNVPTSFVRAYLRASTAEQDASRALETIEAFARERDLIICSYY
                     IENESGSRLERPELFRLLRDCQQNDILLIEDVDRLSRLSGEDWNTLKKMIRQKDIRVMA
                     VNVPTTWINSGMSEFDSRLFAAINDMLLDMLAAVARRDYEQRRERQKQGIEKARKDGKY
                     KGRKPNQARHDAIIRLIESGSSWTQVQKVLGCSRGTISNALKRKTGQKSSK"
                     /name="recombinase family protein"
     gene            complement(22735..22818)
                     /gene="dinQ"
                     /locus_tag="H9201_RS25150"
                     /old_locus_tag="H9201_24880"
     CDS             complement(22735..22818)
                     /gene="dinQ"
                     /locus_tag="H9201_RS25150"
                     /old_locus_tag="H9201_24880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165328.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible type I toxin DinQ"
                     /protein_id="WP_000565612.1"
                     /translation="MIDKAIIVLGALISLLELIRYLLQLMG"
                     /name="dinQ"
     gene            complement(<23382..23495)
                     /locus_tag="H9201_RS25350"
                     /pseudo=""
     CDS             complement(<23382..23495)
                     /locus_tag="H9201_RS25350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001547191.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /name="resolvase"
     gene            23789..24580
                     /locus_tag="H9201_RS25155"
                     /old_locus_tag="H9201_24885"
     CDS             23789..24580
                     /locus_tag="H9201_RS25155"
                     /old_locus_tag="H9201_24885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_050394548.1"
                     /translation="MTKKTLAERFEVLEQEYNSVMSTKYMGTSAFSHRSQEYIDSARSN
                     NWIARAKKLLEDSYGKESDYYKDFNDTQRIAWSSNYQGLVKHYKPIFDAARDDLTYSGT
                     ASTIATKHAELDLIINILNKFPAFCRQLKQRYNERTPLEINDEYDVQDLVHALLLLHFD
                     DVRPEENSPSFAGSSSRQDFLLKKEKIVIEVKKTRRSLGANKIGEELLIDMARYRAHPD
                     CETLVCFVYDPEGWVTNPKGVIDDLEGKDTEGKTRVVIAQF"
                     /name="hypothetical protein"
     Typing          17643..18088
                     /name="IncX1"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.776"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 cggtcataga gtcttccctg acattttgca gggaattcca tgactggaca gcgcattggg
       61 tatatcaggg tcagcacctt cgaccagaac ccggaacggc aactggaagg cgtcaaggtt
      121 gatcgcgctt ttagcgacaa ggcatccggc aaggatgtca agcgtccgca actggaagcg
      181 ctgataagct tcgcccgcac cggcgacacc gtggtggtgc atagcatgga tcgcctggcg
      241 cgcaatctcg atgatttgcg ccggatcgtg caaacgctga cacaacgcgg cgtgcatatc
      301 gaattcgtca aggaacacct cagttttact ggcgaagact ctccgatggc gaacctgatg
      361 ctctcggtga tgggcgcgtt cgccgagttc gagcgcgccc tgatccgcga gcgtcagcgc
      421 gagggtattg cgctcgccaa gcaacgcggg gcttaccgtg gcaggaagaa atccctgtcg
      481 tctgagcgta ttgccgaact gcgccaacgt gtcgaggctg gcgagcaaaa gaccaagctt
      541 gctcgtgaat tcggaatcag tcgcgaaacc ctgtatcaat acttgagaac ggatcagtaa
      601 atatgccacg tcgttccatc ctgtccgccg ccgagcggga aagcctgctg gcgttgccgg
      661 actccaagga cgacctgatc cgacattaca cattcaacga taccgacctc tcgatcatcc
      721 gacagcggcg cgggccagcc aatcggctgg gcttcgcggt gcagctctgt tacctgcgct
      781 ttcccggcgt catcctgggc gtcgatgaac taccgttccc gcccttgttg aagctggtcg
      841 ccgaccagct caaggtcggc gtcgaaagct ggaacgagta cggccagcgg gagcagaccc
      901 ggcgcgagca cctgagcgag ctgcaaaccg tgttcggttt ccggcccttc accatgagcc
      961 attaccggca ggccgtccag atgctgaccg agctggcgat gcaaaccgac aaaggcatcg
     1021 tgctggccag cgccttgatc gggcacctgc ggcggcagtc ggtcattctg cccgccctca
     1081 acgccgtcga gcgggcgagt gccgaggcga tcacccgtgc taaccggcgc atctacgacg
     1141 ccttggccga accactggcg gacgcgcatc gccgccgcct cgacgatctg ctcaagcgcc
     1201 gggacaacgg caagacgacc tggttggctt ggttgcgcca gtctccggcc aagccaaatt
     1261 cgcggcatat gctggaacac atcgaacgcc tcaaggcatg gcaggcactc gatctgccta
     1321 ccggcatcga gcggctggtt caccagaacc gcctgctcaa gattgcccgc gagggcggcc
     1381 agatgacacc cgccgacctg gccaaattcg agccgcaacg gcgctacgcc actctcgtgg
     1441 cgctggccac cgtcaccgac gaaatcatcg acctgcacga ccgcatcctg ggtaagctgt
     1501 ttaacgctgc caagaataag catcagcagc agttccaggc gtcaggcaag gccatcaacg
     1561 ccaaggtacg tctgtacggg cgcatcggtc aggcgctgat cgacgccaag caatcaggcc
     1621 gcgatgcgtt tgccgccatc gaggccgtca tgtcctggga ttcctttgcc gagagcgtca
     1681 ccgaggcgca gaagctcgcg caacccgatg acttcgattt cctgcatcgc atcggcgaga
     1741 gctacgccac cctgcgccgc tatgcaccgg aattccttgc cgtgctcaag ctgcgggccg
     1801 cgcccgccgc caaaaacgtg cttgatgcca ttgaggtgct gcgcggcatg aacaccgaca
     1861 acgcccgcaa gctgccagcc gatgcaccga ccggcttcat caagccgcgc tggcagaaac
     1921 tggtgatgac cgacgccggc atcgaccggc gctactacga actgtgcgcg ctgtccgagt
     1981 tgaagaactc cctgcgctcg ggcgacatct gggtgcaggg ttcacgccag ttcaaggact
     2041 tcgaggacta cctggtaccg cccgagaagt tcaccagcct caagcagtcc agcgaattgc
     2101 cgctggccgt ggccaccgac tgcgaacaat atctgcatga gcggctgacg ctgctggaag
     2161 cacaacttgc caccgtcaac cgcatggcgg cagccaacga cctgccggat gccatcatca
     2221 ccgagtcggg cttgaagatc acgccgctgg atgcggcggt gcccgacacc gcgcaggcgc
     2281 tgatagacca gacagccatg gtcctgccgc acgtcaagat caccgaactg ctgctcgaag
     2341 tcgatgagtg gacgggcttc acccggcact tcacgcactt gaaatcgggc gatctggcca
     2401 aggacaagaa cctgttgttg accacgatcc tggccgacgc gatcaacctg ggcctgacca
     2461 agatggccga gtcctgcccc ggcacgacct acgcgaagct cgcttggctg caagcctggc
     2521 atacccgcga cgaaacgtac tcgacagcgt tggctgaact ggtcaacgct cagtttcggc
     2581 atccctttgc cgggcactgg ggcgatggca ccacatcatc atcggacgga cagaatttcc
     2641 gaaccgctag caaggcaaag agcacggggc acatcaaccc aaaatatggc agcagcccag
     2701 gacggacttt ctacacccac atctccgacc aatacgcgcc attccacacc aaggtggtca
     2761 atgtcggcct gcgcgactca acctacgtgc tcgacggcct gctgtaccac gaatccgacc
     2821 tgcggatcga ggagcactac accgacacgg cgggcttcac cgatcacgtc ttcgccctga
     2881 tgcacctctt gggcttccgc ttcgcgccgc gcatccgcga cctgggcgac accaagctct
     2941 acatcccgaa gggcgatgcc gcctatgacg cgctcaagcc gatgatcggc ggcacgctca
     3001 acatcaagca cgtccgcgcc cattgggacg aaatcctgcg gctggccacc tcgatcaagc
     3061 agggcacggt gacggcctcg ctgatgctca ggaaactcgg cagctacccg cgccagaacg
     3121 gcttggccgt cgcgctgcgc gagttgggcc gcatcgagcg cacgctgttc atcctcgact
     3181 ggctgcaaag cgtcgagcta cgccgccgcg tgcatgccgg gctgaacaag ggcgaggcgc
     3241 gcaatgcgct ggcccgtgcc gtgttcttca accgccttgg tgaaatccgt gaccgcagtt
     3301 tcgagcagca gcgctaccgg gccagcggcc tcaacctggt gacggcggcc atcgtgctgt
     3361 ggaacacggt ctacctggag cgtgcggcgc atgcgttgcg cggcaatggt catgccgtcg
     3421 atgactcgct attgcagtac ctgtcgccac tcggctggga gcacatcaac ctgaccggtg
     3481 attacctatg gcgcagcagc gccaagatcg gcgcggggaa gttcaggccg ctacggcctc
     3541 tgcaaccggc ttagcgtgct ttattttccg ttttctgaga cgacccctag ttgtttgcgg
     3601 tcttgcgtgg cagggagcag gcatctttaa cttgcctttc acagtgatgc tatggactat
     3661 cattagatta attatcgtgg tatcgcttgt atttattact ggaaaattcg gtctatcaag
     3721 agagtttact ttccccgcag cagcagtagg tttagctttt agtttattcc ctgtccttga
     3781 tcatattgcg ttaggttatt ctgctaaaaa tttctatgaa accactaatt ttatggggca
     3841 aacggttcgg gaatttggtg ccagtaaaat tacggtctgg tggggttcga tttatgccaa
     3901 aatagcctat gctagccttg caggtttaat tggatatggt gttaaggtcg ccactgatga
     3961 ttaaaaaaga aaaaccaact tgaagttggt ttttttggca ctgttgcaaa tagagatttg
     4021 agtcgatgat gttcccttta aaaagtactt agagaccgaa aaccctgttg attagacaca
     4081 cttcaccctg aggctgacca taataaaatg acgatgcttg tcctttacgt agtgcacgca
     4141 tgacttcaat acctttaatt gtggcataag ccgtcttcat agatttgaat cctaatgtgg
     4201 ccctgatgat ccgctttagc ttgccatgat cacattcaat cacgttattt ttatacttaa
     4261 tctgcctgtg ctcaaggtct ggtggacatt taccttcccg ttttaaccgt gataaagcac
     4321 gtccatatgt gggtgcttta tccgtgttga tcacttgtgg aatttgccac ttcttcacat
     4381 tatttaaaat ttttccaaga aaacaatatg ctgatttggt attacgtcta gaagaaagat
     4441 aaaaatcaat ggtatcgcca cgttgatcga ctgcacgata cagataagac catcgtccat
     4501 tcacttttac ataggtttca tcaatatgcc acgagctcag atctgtagga ttacgccaat
     4561 accagcgtaa acgtttttct atttcaggag cataacgttg aacccaacgg taaatagtcg
     4621 tgtgatcaac attcacaccc cgttcggcca gcatttcctg cagttcacga tagctaatgc
     4681 catatttaca ataccagcgc acagcccaaa gaatgatttc gccctgaaaa tgccgaccat
     4741 ggaaaggatt catatgctgc acctttagct aaaacagtct tcagcttacc attcgtggtt
     4801 atttgcaaca gtgccgctga cgcacaccat cgcccaccgg gtgggtcgct atctggaacg
     4861 gcaaggcctg ctggaacggg atgtcgaaaa cagctatctg gcctcggatg cggtggatga
     4921 cgacccgatg acacccctgc tggggcactc gatcacttac cgtatcgctg tcggttcaca
     4981 ggcggggcga aaggtgttca ctttgcaaac tctgccgacc agtggtgatc cgttcggtga
     5041 cgggattggc aaggtagccg ggtccagcct gcacgccggc gtggcggcca gggccgatga
     5101 acgcaagaag ctcgaacggc tgtgccggta catcagccgc ccggcggtat ccgagaagcg
     5161 gctgtcgtta acacgaggcg gcaacgtgcg ctaccagctc aagacgccgt accgggacgg
     5221 caccacgcac gtcattttcg aaccattgga tttcattgca aggctggccg ccctggtacc
     5281 gaagcccaga gtcaacctaa cccgcttcca cggggtgttc gcacccaaca gtcggcaccg
     5341 ggcgttggtc acgccggcaa aacggggcag gggcaacaag gtcagggtgg ctgatgaacc
     5401 ggcaacacca gcacaacggc gagcgtcgat gacatgggcg caacggctca agcgtgtttt
     5461 caatatcgac atcgagacct gcagcggctg cggcggcgcc atgaaagtca tcgcctgcat
     5521 tgaagaccct atagtgatca agcagatcct tgatcacctg aagcacaaag ccgaaaccag
     5581 cgggaccagg gcgttacccg aaagccgggc gccaccggct gagctgctcc tgggtctgtt
     5641 tgactgacga gcctgaaggc caacgatacc aatcaaaatg ctgcgttcac agcgccgcgg
     5701 cagggatccg ccgtgctggt tgtcggaaaa ggagccgcta gtgggaaaga ggagggtaaa
     5761 ttttcagcgt tgctggctcc ccgtcagccg gattgggttg catcgcaggg gtgtcgaaag
     5821 agtcaactgc ggtccaaagc tgttggactt gggtgaaaag ggcgtttatt cttcctatac
     5881 gtgccgcgtt ccaggcggcg actatgaggg ctatgtcgat gcccatgtgc gccggctgga
     5941 ggcgctacgc cgggccggta tcgtcgagcg gatcgacgcc gaccaatggc gcatccccga
     6001 tgatctggtc agccgtgccg ccgcccatga cgccggccga gacagtcagg ccagcgttcg
     6061 cgtcctttcc ccggtcgatc tgaacaaaca gatcggatcg gacggcgcga cctggctgga
     6121 ccggcggctg atccacggcg agacggccga ccttgcgcca accggcttcg ggcaacaagt
     6181 ccgcgaagcc atggaccagc gccgcgagca ccatatcgaa cagggcgacg ccacccgcag
     6241 ccgggacagc cgcgtcttct accggcgcaa ccttctcgcc atcctgcggg agcgcgaggt
     6301 agccggcgtc ggatcggata tggctttgag taagggcctg ccgttccgcg ccgccacgga
     6361 cggcgagagc gtcagcggca agtttaccgg aaccgtgcat ctatcgagcg gcaagttcgc
     6421 cgtggtcgag aaatcccatg agttcaccct tgtcccgtgg cggccgatca tcgaccgcca
     6481 actcggccgc gaggttatgg gcatcgtgca gggcgggtcg gtgtcgtggc agttagggcg
     6541 gcagaggggg ctggaacgct gagtgcgccc atgccgcatt gcgaagcaaa agataatcgg
     6601 ataaaatgta gcaattcata ttcgtaagcg tggagtaatc agatgggaaa ttccaagtca
     6661 gcagacaagt aagccgcaac aaccagtatt gttgttgcgg cgctctgtaa ggctagtctc
     6721 atctgattgc tgacgagcag acgtcgcccg gtattcctta atcgagggtt gattcgtcat
     6781 gaccaccaca cgccccgcgt gggcctatac gctgccggca gcactgctgc tgatggctcc
     6841 tttcgacatc ctcgcttcac tggcgatgga tatttatctc cctgtcgttc cagcgatgcc
     6901 cggcatcctg aacacgacgc ccgctatgat ccaactcacg ttgagcctct atatggtgat
     6961 gctcggcgtg ggccaggtga tttttggtcc gctctcagac agaatcgggc gacggccaat
     7021 tctacttgcg ggcgcaacgg ctttcgtcat tgcgtctctg ggagcagctt ggtcttcaac
     7081 tgcaccggcc tttgtcgctt tccgtctact tcaagcagtg ggcgcgtcgg ccatgctggt
     7141 ggcgacgttc gcgacggttc gcgacgttta tgccaaccgt cctgagggtg tcgtcatcta
     7201 cggccttttc agttcgatgc tggcgttcgt gcctgcgctc ggccctatcg ccggagcatt
     7261 gatcggcgag ttcttgggat ggcaggcgat attcattact ttggctatac tggcgatgct
     7321 cgcactccta aatgcgggtt tcaggtggca cgaaacccgc cctctggatc aagtcaagac
     7381 gcgccgatct gtcttgccga tcttcgcgag tccggctttt tgggtttaca ctgtcggctt
     7441 tagcgccggt atgggcacct acttcgtctt cttctcgacg gctacccgtg tgctcatagg
     7501 ccaagcggaa tattccgaga tcggattcag ctttgccttc gccactgtcg cgcttgtaat
     7561 gatcgtgaca gcccgtttcg cgaagtcctt tgtcgccaga tggggcatcg caggatgcgt
     7621 ggcgcgtggg atggcgttgc ttgtttgcgg agcggtcctg ttggggatcg gcgaacttta
     7681 cggctcgccg tcattcctca ccttcatcct accgatgtgg gttgtcgcgg tcggtattgt
     7741 cttcacggtg tccgttaccg cgaacggcgc tttggcagag ttcgacgaca tcgcgggatc
     7801 agcggtcgcg ttctacttct gcgttcaaag cctgatagtc agcattgtcg ggacattggc
     7861 ggtggcactt ttaaacggtg acacagcgtg gcccgtgatc tgttacgcca cggcgatggc
     7921 ggtactggtt tcgttggggc tggtgctcct tcggctccgt ggggctgcca ccgagaagtc
     7981 gccagtcgtc taaccgacga ctggtagcag gcccgctccg atgcggcgca ctaaccatcg
     8041 aaacctcgtg aatgtcggta tcctgtctgg caggataccg ctcatttccc ttgttcagtt
     8101 catcgccgtc gccgagcatc tgaattttcg gcatgcggcc aaggcacttg gtatcagcca
     8161 gtcgagcgtc agcgcgcgtg tgaaagcgct ggaggataac cttggtgtcc tgctatttga
     8221 gcgccatgcg cggggcgttc ggctaacaga cgcaggcagg cacttcatgg agcgtgtcac
     8281 ggcgggtgtc gatcaactcg atcacgcagt gaagaccgcg gagtgacggg cactggctgg
     8341 caatgtctag caacggcagg catttcggct gagggtaaaa gaactttccg ctaagcgata
     8401 gactgtatgt aaacacagta ttgcaaggac gcggaacatg cctcatgtgg cggccaggac
     8461 ggccagccgg gatcgggata ctggtcgtta ccagagccac cgacccgagc aaacccttct
     8521 ctatcagatc gttgacgagt attacccggc attcgctgcg cttatggcag agcagggaaa
     8581 ggaattgccg ggctatgtgc aacgggaatt tgaagaattt ctccaatgcg ggcggctgga
     8641 gcatggcttt ctacgggttc gctgcgagtc ttgccacgcc gagcacctgg tcgctttcag
     8701 ctgtaagcgt cgcggtttct gcccgagctg tggggcgcgg cggatggccg aaagtgccgc
     8761 cttgctggtt gatgaagtac tgcctgaaca acccatgcgt cagtgggtgt tgagcttccc
     8821 gttccagcag gccttgccgt tccagatagc gacccacccg gtgggcgatg gtgtgcgtca
     8881 gctgggtgag ctctgggctg gtcggcgcct tgacccagcg gaaacgcgct gagccgtggg
     8941 attgctcgac atacacaccg tcgagaaaca gcatgtggaa gtgaacattc agattgagcg
     9001 ccgatccaaa acgctggatc agggtgaccg cgcccgtctt ggccacttgg tgggtatggc
     9061 ccgctttctt gaccaggtgc gtggcaatga cgcggtaaac gatgcccagc acccacccca
     9121 tgatctcggg ccggctggca aacaggaaac gcagctgaaa cgggaagctc aacacccact
     9181 gacgcatggg ttgttcaggc agtacttcat caaccagcaa ggcggcactt tcggccatcc
     9241 gccgcgcccc acagctcggg cagaaaccgc gacgcttaca gctgaaagcg accaggtgct
     9301 cggcgtggca agactcgcag cgaacccgta gaaagccatg ctccagccgc ccgcattgga
     9361 gaaattcttc aaattcccgt tgcacatagc ccggcaattc ctttccctgc tctgccataa
     9421 gcgcagcgaa tgccgggtaa tactcgtcaa cgatctgata gagaagggtt tgctcgggtc
     9481 ggtggctctg gtaacgacca gtatcccgat cccggctggc cgtcctggcc gccacatgag
     9541 gcatgttccg cgtccttgca atactgtgtt tacatacagt ctatcgctta gcggaaagtt
     9601 cttttaccct cagccgaaat gcctgccgtt gctagacatt gccagccagt gcccgtcact
     9661 cccactcgat tgtaaacaag cacacaaaac cctttagtga caacaatttg caagaactat
     9721 caggctcagt gccatgaaaa ataccatgac cagatcatga ggttgaacac ggcttgcgcc
     9781 ggcagcgttc acgctcctgg tcggcgatct cgcccggctg caatgctagc tcagcatcgg
     9841 tcatgcgctc cagcacgtcg cgtaggcgga tggtgcaagg aatgggcggc agctcgaact
     9901 catagccgcc ggcgatcatt tcggccgcaa tctcctcggt gatgaaaaac ggctcgtcgt
     9961 cttggttcgg cttcttcatg ccctttcctc ctggcgctca tcctggccga cagcggccag
    10021 ggcatcggct tccgtcaatg cgtcctccac gaacgcgccg tgctgcttcg cttcggcctg
    10081 gctgacctcg gcccatatcc gtttcacctg ggccgcactg tacccggcca gctcggcggt
    10141 cttgttgatg ctgtagccgg acttgcgcag cgcgacaact tgggcgcggc gcttcggatc
    10201 agcacggcgg cccttgtacc gcccggcctg gcgggccaac tcaatgcctt ggcgctggcg
    10261 ttcgcgcctg tcctcgtagt cgtcgcgggc catctgcaag gccaggcgaa aaagcatgat
    10321 ctgcacggct tccagcacga tcttggcgac gccctgggcc tcggccgcca ggtcggatag
    10381 atcgaccacg ccagggacgg ccaggcttgc gcctttggcc tgtatcgagg ccaccaggcg
    10441 ctcggcctcg ggcaaaggta ggcggctgat gcggtcgatc ttctcggcaa tgaccacctc
    10501 gccgggctgt aggtcgccga tcatgcgcag cagctcaggc cggtcggcgc gtgcgccgga
    10561 tgccttctca cggtagatgc cggcgacgta gtagccggcg gccttcgcgg ccgtagtgat
    10621 cgcctcttgg cgttccaagt cctgcgcgtc ggtgctgacg cgcagataga cccgcgccac
    10681 catcggcgcg gctactggct tcgtcctgcg catacttgcg ggctcctttg ggcatacgca
    10741 aagtgtccgg tcatgctacc cccggccaaa aaggccgtca tgcgatttat cttggccggg
    10801 tcgttattgg cgggtctaaa tggccgctcc gtggatctca tcgccagaaa tggcgatgcg
    10861 agatccaggg cagggcggcc gccatcgtca gacctggcga tggtcgacgc cggcgcgcat
    10921 cgtcggatgt ggcgatgcga gctcgaggtc ggtggccacc gccggcgacc tggtgccatc
    10981 gtcggcaatg gcgatgctgc agctcgacgt gcgcggcctg gtcgtctcgg catcgtcgga
    11041 tgcggcgatg ctcgagcgag gcgaaaaaaa accgcctcgg ggtgtccgag gcggcaagtc
    11101 tgcatgcggt tcagggagga agaaaccgcg ccggcgatca gggaggaaaa ccgcgcggcc
    11161 tgatgtgcag ctcggccact ttagccggat ttttcgactt atccgatgcg agcggcccgc
    11221 cgtgggcgct gctcgatctg ctgttgcttt ttctcgacgt gcttctgctc ctggtgctgc
    11281 tgctcgtcgc gcggcactgt tgcaaagtta gcgatgaggc agccttttgt cttattcaaa
    11341 ggccttacat ttcaaaaact ctgcttacca ggcgcatttc gcccagggga tcaccataat
    11401 aaaatgctga ggcctggcct ttgcgtagtg cacgcatcac ctcaatacct ttgatggtgg
    11461 cgtaagccgt cttcatggat ttaaatccca gcgtggcgcc gattatccgt ttcagtttgc
    11521 catgatcgca ttcaatcacg ttgttccggt acttaatctg tcggtgttca acgtcagacg
    11581 ggcaccggcc ttcgcgtttg agcagagcaa gcgcgcgacc ataggcgggc gctttatccg
    11641 tgttgatgaa tcgcgggatc tgccacttct tcacgttgtt gaggatttta cccagaaacc
    11701 ggtatgcagc tttgctgtta cgacgggagg agagataaaa atcgacagtg cggccccggc
    11761 tgtcgacggc ccggtacaga tacgcccagc ggccattgac cttcacgtag gtttcatcca
    11821 tgtgccacgg gcaaagatcg gaagggttac gccagtacca gcgcagccgt ttttccattt
    11881 caggcgcata acgctgaacc cagcggtaaa tcgtggagtg atcgacattc actccgcgtt
    11941 cagccagcat ctcctgcagc tcacggtaac tgatgccgta tttgcagtac cagcgtacgg
    12001 cccacagaat gatgtcacgc tgaaaatgcc ggcctttgaa tgggttcatg tgcagctcca
    12061 tcagcaaaag gggatgataa gtttatcacc accgactatt tgcaacagtg ccactggatc
    12121 atggtaagga actattcctg acctacaaac aaattatacc atcaaatgat ggtaatgcaa
    12181 tttatttagt ctctttattc tgattttttt ctcgctttac tagctggtaa tcgggatgtt
    12241 catcagccag gagcaaaagt aattcatacg taccagcggc tagaccgcga gatgttttgc
    12301 cggatgtttc tttggcctgc caggctgata acgaaaaacc aaaccgttta gcggcttcct
    12361 gctgcgtaaa gccagctttg atacgagctt gtttcacctc ttcaggtgtg ggtttaaaac
    12421 tcatgattta gtaccttcac aatagtatct gtatagaatt gcaataaaat tggatcatca
    12481 atttcatctt taacgttaca gaattcttca taataaaatg atttatggaa aacaaccttt
    12541 ttagttgttt ttttatccgc ttctttagag cgaactttca ttagtttttc aagttcaata
    12601 aacaaacgtg ttgcatcttc agacacaaca atcctgtatg ttacattacc tttatttttc
    12661 ctgtcgctca ggacttcatt catcttttgc ctcatagctg tttaataaac cccgctacct
    12721 ttatgagctg atccacactc aggccacgta ttaccatttc aaaaccgccg ccccgttctg
    12781 acacgttacc atctaaccca ttctcaactt taaaaccggt caatgtccca tgccagctat
    12841 caagacgtat taaacgagat agcattcctt tcagaatttg cgtttgctcc cgtttttttt
    12901 gtaactgcct ttcatattcc attgccttct ctacattttc gaaagcatct gtcaggattt
    12961 tcttttcaat atcggcggca atttctacag ggttacgttc tggcgataca gtgcaagtat
    13021 ggtaaggact tcgccaactt cgactatcta cgcttccaat gataactaac cttcccttct
    13081 ccattcgaat atgtatagag taatttttat actgaggcga ggttagtttt atcctgtact
    13141 ggcaatcatc gagcaggttt acacgccagc cgttccccag gattcgacat acgatttcaa
    13201 aaacgggttg ataccgttca aaaaacttat cgttttgcat atccctccca actgacacct
    13261 tcgttattta gtgaacatat ttataataat aaggggcttt cgcccccttc tggttacgct
    13321 ctggtttcca cttgttgcca tcccgtcgcc ctgcgctgtc cggtcgaacc atattttgcg
    13381 cggatttcct ctatcgtgtg ttcttcacgg ttccagtaac ttttatgttc ttccggacga
    13441 taaaaccatt gttttttctt tgcggcccat ttacacccga tttcttttaa cgtttcttta
    13501 tgagtaatgg tttcaccact aatccatacc caattaccaa taacttcata gacaattcca
    13561 gtcaggccgg aaagagtatt caaaactttt tccagatctt caccgtagtt gtaacgtgcg
    13621 ttttcatcag tgctttgaaa ctgattaatt ttgtcaatgt tagccatgag aaaatcaaac
    13681 gcagcgttaa ctgctttcat cagttcggca cccagtggat tacgatctgg atgatatttt
    13741 aaagccgctt ttctgtaggc cgccttgatg tccttttcag tcagatcgcc ggataaacca
    13801 aaaatgttta atgcttcctg aatattcatt tttcgctccc gcccgtttgg gctgctggaa
    13861 tctggcaggg aaccattccc aaccaacaaa ctcatcatac catcatatga tggtatggca
    13921 agttttttat gcccgtcagg gcatggaagg cgacacacca gacgccgaat agaattgcca
    13981 ttcccgaatc gccggaaaca aaccagctta attaagatca gggacatccc ccctccctgc
    14041 aaagcccatt accggactaa caacacgcaa ttagcctttc gcagttagcg cgtaagcttg
    14101 cgaacggtac gccgtgacgg tgtgtagcat ctgcgcgtct gagcggctgc agccgcgaat
    14161 tacggggcgg gtttcagttc agcgcatatc tgcaatctga taaacttcgc tgctttccct
    14221 tcttccaaca gcaataacga gtaaaacgac tttctcatca atgacttgat atacaagtct
    14281 gtagccagat gcacgaagtt tgattttata gcgatcagca tgaccatgta accgggctgc
    14341 gggtacgcgt ggattttcca gccgttctgc cagcttcttt ttgaattgtt cacggatggt
    14401 gtggccgagt ttctgccatt ccttcagtgc tctgcggtca aaagccagtt cataggtcat
    14461 ccaggttaac cttcacaatt tccgggtttt tcatgcgctc atcagcaaca gcgtttaact
    14521 cagcatcttc agcgagttcc cgatagtagg cgtaaagttt tggtggaacg caatagaacg
    14581 ccggttcgtt tcggttcagg atcgcaacag cgtccccttc accttcagct acggttccca
    14641 taggattttt tttcaggtca gtaatactgg ccgctgtggt tgtcagaatt tgatagctca
    14701 taagtcctcc gcttgtctta ttggcataat agcatcttta aaagtactct taaaagtgct
    14761 tgtgctgaga aaaacatcag aacaggtgag gtatggctct ttccgacatc gccttaaaac
    14821 gctctgtaac gcgttctgag cgttttttcc cgtttcgtta tagtcagcta cggtttaacg
    14881 gtttttaacg ccgctcaacg ctttttagcg gccttgttgc tgtgatctgt tgccatgatc
    14941 cggataggag ttcaatcttg atcaaaattt cctcaaggca acgactgttt tgtaaatacc
    15001 ctctaaaacg cgctgtatcg cattctgagc gattttttcg atttcacatg gttttcctca
    15061 tggttacatc gaacaaagcg ttagaaagcg attcagggct tctcagtgaa agatccaaaa
    15121 aggatcaatc aacggatcgt atgatctgaa ctcttctggt tttgagaaag gagacaccgc
    15181 tcgccgcagc cgaacgaccg agtgtagcga gttagtgagc gaggaagcgg aacagcacag
    15241 ggataacatc aggcaattac gcgcagtggt taaaaagcga gcatattgtt tttatgtgtg
    15301 gttgtcttgg ttcagagtga tctgtcctct gggtttacgc aaagttatcc acaggtagtg
    15361 tgaatttttt gttttgagca aagttatcca cagatttttt gtgttttttt gcttattaaa
    15421 cttcttgttt ttaagatctt aaatgtagat cggtagatct actttaagat ctttaactta
    15481 ctctaactta ttctgcaaac attgtgccag tttttttatc aataatttca ttaagatagg
    15541 tgttgttttt tgtcgcctca aaatgaaagg tggatgggta cgcactgaaa ggtggatggg
    15601 tacgcactgt aattttcatg aaaggtggat ggctgcgcac tgaaaggtgg atgggtacgc
    15661 actgaaaggt ggatgggtac gcatttttct gtttttattc agatattcgt atctttgtat
    15721 cttcatttct ttagttcttt atagtgctct aatctaacgt atgacgttaa aaggtggata
    15781 cctgcgcatt tctatcatat tgaatataaa tgataaaaat tctttcatgt gatccgtgtt
    15841 ttggtggaaa catataaggt ggataaacca ctttacatat ttccgccttt gtggttatga
    15901 tttcaccata agaacttaaa aaccaaaggt aatgtatgaa cttactgagc gttacaaaga
    15961 aaacaaaaat tcgccacaga aatgaaatta acagcacatt ctcatcgttg cctttgtctg
    16021 ccagaagaat tttgtttatg gctatggcgc agattgattc acgtgaagag ttatctgagg
    16081 gggcaacctt tcgtattacg gctcgggaat atgcatttat cgctgatatt gatgtaacag
    16141 gtgcttaccg gcagttgaaa gagggggcag aagaacttca ggccagtgtt attcgtattc
    16201 ctcgaaatca acttctcaca gctcagggca atcaaagctc tggacatacg aagaagagag
    16261 gtaaattacc ttctgatgca gtcaggctta tgaacctgac tgcgttttgt gattatgttg
    16321 aaagtgaagg atatattgat attgcttttt cacatgtcat tgagccatat atcacgatgt
    16381 taaaggattc ttacactact caggttttga tatcgtctgt aagactcgct gatcaaaatt
    16441 caaatatgct ttatcagttt atcaggaaac aatacagcag tggtaaaaag acatttttcg
    16501 acattgaagt agatgtatta aaggatgaac ttgaattatt cagaatagat aatggcgaaa
    16561 aagtttacct ttatcagaat tttaaggatt ttaataaggt ttttctgcaa aaaaatattg
    16621 aaaaaataaa tcaatataca gagattaatc atctcgaagt taaaattgtt gagagagtcg
    16681 caagaagagc atcaaagcta agattttcgt ataaaataga taaagaaagc gaaggacttg
    16741 ataccagaat accgtatggt ttcagaggtg cttaatatat aaaggtaaat acactatgga
    16801 gcaaataaaa ttacataaac aaggtggtgc ggcagtaatt atcattcctg ctagtatgat
    16861 agaaaataca ggatgggaag atggaacctt attggaggta ctagaaataa atgagactct
    16921 tcatataaga agaaagacag aatcaggagc tttagctact aaagcttgtc cttctctttt
    16981 ttcatctact atgaggcatg ttaattacga taaaatcatt agatataata gcggattaaa
    17041 tctgttagtt aatgaactgt cattttcggc aagaagggtc ttttttattt gtttatatta
    17101 ttactttgaa aataaacttg aatcggataa gtcgctattg atccgggctg ataagtatgc
    17161 agaatttgtt ggtgttgagc gttctgtcgc atataagcaa atgaaggatg cagcagattt
    17221 cttttcaaga aataaaaatt taattacaca ttgtgactat atttcgaatg agggattgct
    17281 tcgtgttatg ttttcgtcta agacgataaa ttatattaca gcgatagact cccgtaaata
    17341 tcaggttacc gagcttcctc taaaatctgc tttgtctctt caaggaagat actcatggcc
    17401 tttatatcaa ctgataaaat ttagccatct taaatctttc actataggtg tagatgaact
    17461 taagaaagaa ataggttata ttcaaaatca aaagttttct ttctttaaaa gagatggaat
    17521 caatatagct attgatgaaa taacagaaag gacagatgtt aaaaacatta aatgtgttaa
    17581 tgctgaaagg caggggagaa gagtcagcaa agtccgtttt gagatcgaaa tgaggtaact
    17641 catggctaaa atctatcaat tccctcaggg ggaagaacga gctaaattca ggaaagaaat
    17701 cgccagggag cgtaagaaac gttttgcagt gaaaacaggg agcacttttg ttaagtggct
    17761 tggctgggga tggttttatc ttcgtcttct tgccgcgagt gttttacatt ttatctttgt
    17821 ttttgtgtta gccattcttg gtgcgtttaa atgggctgtg ttctggctgg gggggatttt
    17881 gtgtgtcatc acctggtatc atctcgatca ccagttatgg acgccacaaa atctgactat
    17941 accggtgatt acggcaacct ggattttggg actgctggct gagcctctga tggagctgct
    18001 caacaaaact atgccctggc acaagttact tgttcccgaa cctgcggacg aaagcaccga
    18061 gaacagtagc gagataagcc agcaatgatg ctactcagca gttatgccag tccctgcctt
    18121 ttcactgcga tgcaggatag ggcaaacgcc gcaaaatgac gtctctgacg ccattccgca
    18181 acgtttgccc ggtgacctac agtcggttct tgttggagaa ttttatgaaa tatcaggtga
    18241 gaaaatttat tactgataaa tatgcgaagg ctgttaatat tttaaaggat aatcttaaag
    18301 aacactatca tgttttttat ggtgttagat taagtgagat tctttttcct gccggtgagt
    18361 atggctctga acaatttttt agtgattttg aaaagataaa ctcgatttta ttacctcttt
    18421 tagtgtttga tctcaaaacc gatgttcctg tgattgtcat tagccttgat gatgtcagtt
    18481 attgtgatgt tctgaacgaa atagatattg attttatgaa atgtaattcg ctggcagaat
    18541 tgcttaccag cgataagctg gatgcgttat ttaaggattg actcttatgt tccttctctg
    18601 tctactggat gagaatgccc ccggtatgaa actgaagtgg gttttctaag tactcaggta
    18661 gtgcaattat ctttttattt ttaacagaat ttctgtacca gtattcaaaa gcatacttgt
    18721 tcatctttag ctggctttta gggacaaaaa acaatctgta attgccatga taatgacttg
    18781 gttccagcat gtctgtatgc ttgctgacca ggctattgaa cagattaaat aatgtattta
    18841 tgttggtttg atatctgaag tttagtataa aagaccagta atcactattc agttttttta
    18901 tggagacttt atcaatgctg agtttagtta tattggcttc ccttttgtat tcaagtttgt
    18961 ctcgaactga ttgccagaca acaagggctg cgtgatgaga acctccatta tttgatacaa
    19021 aatacctatc aagccatgtg tagtatgtta tttcaattgg cctattacga cggaatcctt
    19081 cttcttctat atgttgtata ttctttttcc agtcggactc gtcttctgcc ctgagttttt
    19141 ctgtgtgacg cattcccttt ccccacgaat acaggtctct gtagcaacta gggtttttac
    19201 ttttagctgg aagatgttcg aaactcttgg agttttcaag agactggagc ttactgaaat
    19261 caaagttatg tatatgttca acttcaattt ttataagctt tctgagtatc ttttcaaggc
    19321 gaggggatat atttttattg gacatatcct caagttttaa tatagttttg ccatccactg
    19381 tgatggcgtt cagagtgata tcatccagat atttattaat gtcttttacc ataaattcga
    19441 ttgtgtttac tatattcatc attacttaat attccttttt cattccattg tgttttgtgc
    19501 tattttctct tttacaaaat tatataattt ttcggtttct tcttcatttt taaacactct
    19561 ttctgggatg atgatgcatc tgttttcttt tgtctggata aacagaaatc cttgctttcg
    19621 gtatgtcttt tttatgttat tccagaaaac cctcgaacta ccaattttca tgacttgttc
    19681 aatgtatgaa cgatttattt ttagacgtaa cattagttct tggtctttta tttctgatga
    19741 atggttactc ctcattattt ttttcattaa ataatcatat atatataaca gaccgataaa
    19801 tatagctatt agtgtaaatg taaggatgga aagaaatttt gctctttcta cataatcagg
    19861 ggcttttggg gctagagtaa tcaaacaaaa gtattataaa atcaaataat gctgcaaatg
    19921 aaagaactaa caatgctgcc ttttttataa gcaaaatata gccataaggt tctatatttt
    19981 cttgtttttc atgctctttt atcaatttgc ttgcttctgt tttttccaaa acagatagcg
    20041 tgaagttaat actgtatcta taatctgatg caatttttct tcctcgatat tatgctgtta
    20101 agcagttcta aaccagaacc agacaacaaa accaatcatc actatggtca aaagtgaatc
    20161 aattactatc cgtatgacaa acgtatgatc tccacgataa taataaacag gcggagccat
    20221 cttgcgatgt tctttataaa ttcctttttt ataggatctg tagttatcaa ataacctcca
    20281 gcatcccaat aaaagaccaa ctaatacgat gaatattctc attattattt tgcctttcct
    20341 gtcctcaatc agtaagacgg ctcgacaatc cttattccat actcacaggt aaaggcttta
    20401 ttgcttctgt gagctaacct aactttgcag attcaagcag ccaatggttt ttccggttct
    20461 cgtccaggct atcgaaagcg gccagcgccg ctttaaggat ggttgttttg ctctgtcttg
    20521 ttctgctcgc ttcggcttcc aggatttctt tatagacttc ggttagccgg aaattcagta
    20581 ctcttgcttt tgctatcaat tgcttactgt tttcttcagg aatatggttt gctgaaggat
    20641 ttagttttga tgtgacttct gttatcacct cttcaggtaa cgcttctaat agcgttctca
    20701 gcgcatcaac gattttttta tccatgatat tcctcaaatt ttattcgttc tctttgagcc
    20761 agttatctac aagctggttc accacgtcag taattgatgt acctttcctg gcgcatgcag
    20821 ccttaaaccg ggtgtgcttt tcttcatcaa aattaacgtt aacacgtttg atttttccag
    20881 atgatactgg tgctgttact actcgttcca gatctctgtt ttcaccaaag gtcatttttt
    20941 ttactgacgt atgcgctttt tcaagtgaca ttcaggctac tcctgttttt atacttattt
    21001 gattatatga gtaaatgtgt aattactcaa atattctaac tatctctttt gtaaggattt
    21061 ctatttcacc ttttgcagcg ccatcactgg attcaaacac gctgtcgcca tcaagaatcg
    21121 atttcacgta aacctgacgt tgtgtaatag ctgtacgaaa tgctttaaca ccggtgtctt
    21181 tgatactttc tttaagcaca ttcaacatgg ttgccatttc tatcttacgg gtgataagaa
    21241 agcgggcttc tactttgcgg ctgtaagcct gtgcttccag gactgtaacc acacttcctg
    21301 ctgcggagaa atccagaggg ctgggggtga cagggataat taccaggtcg cttaccataa
    21361 cggctgcgga tgtgattact gagagtgaac ctgccccgtc cacgatagca aagtcatagt
    21421 ccgccagatc ttttcgaatt ccatagacgt ctttttctga tgctgctgta aatacgtcaa
    21481 atgctgcttt gcctgctttg ctccagttcg tcaggctcat ttgtggatct gtatctacca
    21541 cagcaatgtt gtatccgctt ctgctcaacg cagtggctat gttgattacg gcagttgttt
    21601 tacctgaacc ccctttcgga ttcagaaatg agatcacttt catacttaaa tactcaattg
    21661 tgtgtctact caattactcc tgtgagtttt tgagtttacc atactctttg tatgagtaaa
    21721 ggttaatatg agtctatgta tatatgagtt aaagagtgtt tactcatatg ggtttttgtg
    21781 tgtgtgggca tttgagttta tgagtgtata gtgacaaggt cacatctact cattatttgt
    21841 tttttggttc ttttagagtg tgcctttcct gtcgatctac tttctggtgc attttgggta
    21901 tagtggtgtg accttatgtg aaccggttct gtaatatgac ttcaaatgta ccaacaagct
    21961 ttgttcgcgc ttatctgaga gcttcaacag cagaacagga tgcttcgcgt gccctggaaa
    22021 ctatcgaggc ttttgccagg gaaagagacc tgatcatttg cagctactat attgagaatg
    22081 aatccggctc ccgtcttgag cgcccggaac tttttcgtct tctgagagat tgccagcaaa
    22141 atgacatttt gcttatcgag gatgtggaca gactttcccg cctgtcaggg gaagactgga
    22201 atacgttgaa gaaaatgatc cggcagaaag acatccgggt tatggcggtg aatgtgccga
    22261 cgacatggat taattctggt atgagtgagt ttgacagccg gttgtttgca gccattaacg
    22321 atatgctgct ggatatgctg gccgcagttg ccagaaggga ctatgaacaa cgtagggaac
    22381 gccagaaaca agggatagag aaagcaagga aagacggcaa atataaaggg cgtaaaccta
    22441 atcaagccag acatgatgca attatcaggt tgatagaaag cggtagctcc tggacacagg
    22501 tacagaaagt gctagggtgc agccgtggca caatcagtaa tgcgctaaaa cgtaaaaccg
    22561 ggcagaaatc cagtaagtag aggagtaggg ggctaatata cctgcaaggc aggatattaa
    22621 ctcaggagat tgggtgtgtg gtgtttagtc aatgcatttg aatattgtaa ctaaaatatg
    22681 tttttattaa aggccggagg tggttagccc ccggccttag ttacgtttcc gccatcagcc
    22741 catcaactgg agaaggtagc gaatcagttc aagaagcgag attagtgccc ccagaacgat
    22801 gattgcttta tcaatcatcc gtttactcca ttatatggag cagactcccg atacttactc
    22861 ttacactgcc tgtcatatcg gttgttcttc ggtgttggtt gaagacagtt ccactccagc
    22921 cagagcactg acaacagcac cacctgtttt tcagccagga cttaaaatcg cttaatcctt
    22981 gcgggaaggc tggagttata acggatcaga accaaccggt gtattatacg cataagcgga
    23041 tacggttgca ttccatatca tgtagacata ttatgtctat gttggttgaa gagagttctt
    23101 ctccagtcag agccaccaac tcagggctgg aaaacacaaa aaagcccgat tacccgtcgg
    23161 gtttttttgt gcctgtcgtt tgcctgtact tccgtttttt ccccttcatt tgagggattt
    23221 ttcttttatt ttttgttgca gccaatactg ctgatcgcgt tggccaacag aacgatgccg
    23281 ttaccggcat tatcatgaat cccgtttttt cagtaagttg cagcatacaa agtaattaaa
    23341 aaaacgtcat tttttgttga tggatgcagt agcggtggtg tgctacgtga aatctggaaa
    23401 attttggcgg gtaagtgact caatttttta atctccgcac ctgtttttct ggacgtgcca
    23461 gcaattatga cctgaagcag aggtgcgtcc gacaacaaaa attccgatca ccaaaaaaaa
    23521 atttggacat tttttccgat aatgcatttt tgtccagagg aatatgaacg acagggcagg
    23581 gtgaaaagga agcggttatc ctgaataacc caggatatgg gcacatatgt cggaacaggg
    23641 caccagataa aggaacagaa catgtgaatg ttgtaactaa ttaggtatgg acagaattac
    23701 ctgaatgtcc aatgtgaacg gaagaaagcc agacatggta gaatattaaa attcacagat
    23761 attattagca tataatttgg attgcactat gacgaagaag accttagctg aaagatttga
    23821 agtgcttgaa caagagtata attctgtcat gtcgacaaaa tatatgggaa caagtgcatt
    23881 tagtcacaga agccaggaat atattgattc ggctagaagt aataactgga ttgcaagagc
    23941 aaaaaagtta cttgaagaca gttatggaaa ggaatctgat tactacaaag attttaatga
    24001 tacacaaagg attgcttggt ctagtaatta tcagggattg gttaaacatt acaaacctat
    24061 ttttgatgca gccagagacg atttaactta ctccggcacg gcatcgacta tagcaacaaa
    24121 acatgcagaa ctggatttga ttataaatat actcaataaa tttccagctt tttgtcgtca
    24181 attaaagcaa cgatacaatg aaagaacgcc gcttgagatt aatgacgagt atgatgtaca
    24241 ggatcttgtt catgctcttc tgctgctgca ttttgatgat gtcagacctg aagaaaattc
    24301 acctagcttc gcaggttcat catccagaca ggattttctt ctgaagaaag agaagattgt
    24361 cattgaagtg aagaaaactc gccgctctct aggggcaaat aaaattggag aggaactgct
    24421 cattgatatg gcccgttacc gtgcacatcc ggactgtgag acgctagtat gctttgtata
    24481 cgaccctgaa ggttgggtga ctaaccctaa aggtgtgata gacgatcttg aggggaaaga
    24541 taccgaagga aagactagag tcgtgatagc tcagttctga ttttcactat gctggacaga
    24601 atcacctgta tgtccaagtg tgcgaggaat tgtgatcgta ctacaaccag tgtcaacctt
    24661 cctataatgc cgataatctt ctataagggg gagcccgcag aattcggaaa aaatcgtacg
    24721 ctaaggtttt ccgggcatcc gtaagggccg aaacttcccg tcttccagtc tgcggctctg
    24781 ccgccagacg taatcgccgg ttaggttgat gtgctcccag cccagcggcg acaggaattg
    24841 cagcagctcg ccgtccaccg gcttgccggc ctcgaccaac ccctgggtgg cg
//
